-
An efficient enantiospecific synthesis of neuroactive glutamate analogs
査読
Tsukamoto Shuntaro, Itagaki Hiyori, Morokuma Kenji, Miyako Kei, Ishikawa Yuichi, Sakai Ryuichi, Oikawa Masato
Heterocycles
101
(
1
)
91
-
98
2020年
-
Photoremovable NPEC group compatible with Ns protecting group in polyamine synthesis
査読
MIYAHARA Masayoshi, SHIOZAKI Hiroki, TUKADA Hideyuki, ISHIKAWA Yuichi, OIKAWA Masato
Tetrahedron Letters
59
4259
-
4262
2018年10月
-
Studies on Aculeines: Synthetic Strategy to the Fully Protected Protoaculeine B, the N‐Terminal Amino Acid of Aculeine B
査読
SHIOZAKI Hiroki, Miyahara Masayoshi, OTSUKA Kazunori, MIYAKO Kei, HONDA Akito, TAKASAKI Yuichi, TAKAMIZAWA Satoshi, TSUKADA Hideyuki, ISHIKAWA Yuichi, SAKAI Ryuichi, OIKAWA Masato
Org. Lett.
20
3403
-
3407
2018年5月
-
Prins reaction using trioxane for trisubstituted, cis-fused hexahydro-2h-furo [3,2-b] pyran derivative
査読
Oriel Hlokoane, Hiyori Itagaki, Manami Chiba, Taiki Noda, Yuichi Takasaki, Kei Miyako, Ryuichi Sakai, Yuichi Ishikawa, Masato Oikawa
Heterocycles
96
(
3
)
453
-
460
2018年
-
A monocyclic neodysiherbaine analog: Synthesis and evaluation
査読
Koichi Fukushima, Yuichi Ishikawa, Ryuichi Sakai, Masato Oikawa
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
26
(
21
)
5164
-
5167
2016年11月
-
Synthetic study of strongylophorines: stereoselective construction of the characteristic lactone bridge
査読
Yuya Oikawa, Daiki Uchiyama, Takuya Shirasawa, Masato Oikawa, Yuichi Ishikawa
TETRAHEDRON LETTERS
57
(
35
)
3949
-
3951
2016年8月
-
Three-Component, Diastereoselective Prins−Ritter Reaction for cis- Fused 4‐Amidotetrahydropyrans toward a Precursor for Possible Neuronal Receptor Ligands
査読
Chiba, M, Ishikawa, Y, Sakai, R, Oikawa, M
ACS Comb. Sci.
18
(
7
)
399
-
404
2016年7月
-
Studies directed toward synthesis of taepeenin D: construction of the C4 stereogenic center and the CD benzofuran rings
査読
Yuichiro Nakazawa, Meri Nagatomo, Tsuyoshi Oikawa, Masato Oikawa, Yuichi Ishikawa
TETRAHEDRON LETTERS
57
(
24
)
2628
-
2630
2016年6月
-
Asymmetric Organocatalytic Cyclopropanation on Chiral Menthyl Acrylate for the Synthesis of (–)-trans-2-Aminomethylcyclopropanecarboxylic Acid [(–)-TAMP]
査読
Sugeno, Y, Ishikawa, Y, Oikawa, M
Synlett
25
(
7
)
987
-
990
2014年4月
-
First enantioselective total synthesis of (-)-dysibetaine CPa and absolute configurations of natural product
査読
Michihiro Sakai, Yuichi Ishikawa, Satoshi Takamizawa, Masato Oikawa
TETRAHEDRON LETTERS
54
(
44
)
5911
-
5912
2013年10月
-
A Synthesis of (–)-cis-2-Aminomethylcyclopropanecarboxylic Acid [(–)-CAMP]
査読
Oikawa, M, Sugeno, Y, Ishikawa, Y, Tukada, H
Synlett
24
(
7
)
886
-
888
2013年4月
-
Studies on an (S)‐2-Amino-3-(3-hydroxy-5-methyl-4- isoxazolyl)propionic Acid (AMPA) Receptor Antagonist IKM-159: Asymmetric Synthesis, Neuroactivity, and Structural Characterization
査読
Juknaite, L, Sugamata, Y, Tokiwa, K, Ishikawa, Y, Takamizawa, S, Eng, A, Sakai, R, Pickering, D. S, Frydenvang, K, Swanson, G. T, Kastrup, J. S, Oikawa, M
J. Med. Chem.
56
(
6
)
2283
-
2293
2013年3月
-
Biology- and diversity-oriented domino reactions for synthesis of AMPA receptor antagonist IKM-159 and analogs
査読
Oikawa M, Kasori Y, Katayama L, Murakami E, Oikawa Y, Ishikawa Y
Synthesis
45
3106
-
3117
2013年
-
1-Hydroxy-2-methyl-2-propyl Isocyanide (HMPI) as a New Convertible Isocyanide for the Ugi Four-Component-Coupling Reaction
査読
Oikawa Masato, Sugamata Yutaro, Chiba Manami, Fukushima Koichi, Ishikawa Yuichi
Synlett
24
(
15
)
2014
-
2018
2013年
-
Total Synthesis of (±)-Dysibetaine CPa and Analogs
査読
Oikawa, M, Sasaki, S, Sakai, M, Ishikawa, Y, Sakai, R
Eur. J. Org. Chem.
2012
(
29
)
5789
-
5802
2012年10月
-
Synthesis and biological evaluation of molecular probes based on the 9-methylstreptimidone derivative DTCM-glutarimide
査読
Eisuke Ota, Masatoshi Takeiri, Miyuki Tachibana, Yuichi Ishikawa, Kazuo Umezawa, Shigeru Nishiyama
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
22
(
1
)
164
-
167
2012年1月
-
Total Syntheses of Amphidinolides B, G, and H
査読
Akihiro Hara, Ryo Morimoto, Yuki Iwasaki, Tsuyoshi Saitoh, Yuichi Ishikawa, Shigeru Nishiyama
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
51
(
39
)
9877
-
9880
2012年
-
Design and synthesis of biotinylated DHMEQ for direct identification of its target NF-kappa B components
査読
Tsuyoshi Saitoh, Masatoshi Takeiri, Yuko Gotoh, Yuichi Ishikawa, Kazuo Umezawa, Shigeru Nishiyama
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
21
(
21
)
6293
-
6296
2011年11月
-
Inhibition of macrophage activation and suppression of graft rejection by DTCM-glutarimide, a novel piperidine derived from the antibiotic 9-methylstreptimidone
査読
Masatoshi Takeiri, Miyuki Tachibana, Ayumi Kaneda, Ayumi Ito, Yuichi Ishikawa, Shigeru Nishiyama, Ryoichi Goto, Kenichiro Yamashita, Susumu Shibasaki, Gentaro Hirokata, Michitaka Ozaki, Satoru Todo, Kazuo Umezawa
INFLAMMATION RESEARCH
60
(
9
)
879
-
888
2011年9月
-
Synthesis of the C7-26 Fragment of Amphidinolides G and H
査読
Akihiro Hara, Ryo Morimoto, Yuichi Ishikawa, Shigeru Nishiyama
ORGANIC LETTERS
13
(
15
)
4036
-
4039
2011年8月
-
Synthesis of Key Fragments of Amphidinolide Q – A Cytotoxic 12-membered Macrolide
査読
Kawa, K, Hara, A, Ishikawa, Y, Nishiyama, S
Molecules.
16
(
7
)
5422
-
5436
2011年7月
-
A synthetic approach to carbazoles using electrochemically generated hypervalent iodine oxidant
査読
Daichi Kajiyama, Keisuke Inoue, Yuichi Ishikawa, Shigeru Nishiyama
TETRAHEDRON
66
(
52
)
9779
-
9784
2010年12月
-
A new NF-kappa B inhibitor based on the amino-epoxyquinol core of DHMEQ
査読
Tsuyoshi Saitoh, Chika Shimada, Masatoshi Takeiri, Mitsuhiro Shiino, Shigeru Ohba, Rika Obata, Yuichi Ishikawa, Kazuo Umezawa, Shigeru Nishiyama
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
20
(
19
)
5638
-
5642
2010年10月
-
Electrochemical construction of the diaryl ethers: a synthetic approach to o-methylthalibrine
査読
Yu Naito, Takamasa Tanabe, Yuki Kawabata, Yuichi Ishikawa, Shigeru Nishiyama
TETRAHEDRON LETTERS
51
(
36
)
4776
-
4778
2010年9月
-
A Novel Approach to Indoloditerpenes by Nazarov Photocyclization: Synthesis and Biological Investigations of Terpendole E Analogues
査読
Fatima Churruca, Manolis Fousteris, Yuichi Ishikawa, Margarete von Wantoch Rekowski, Candide Hounsou, Thomas Surrey, Athanassios Giannis
ORGANIC LETTERS
12
(
9
)
2096
-
2099
2010年5月
-
Synthesis of Tetrahydropyrroloiminoquinone Alkaloids Based on Electrochemically Generated Hypervalent Iodine Oxidative Cyclization
査読
Keisuke Inoue, Yuichi Ishikawa, Shigeru Nishiyama
ORGANIC LETTERS
12
(
3
)
436
-
439
2010年2月
-
Efficient synthesis of (±)-parasitenone, a novel inhibitor of NF-kB
査読
Saitoh, T, Suzuki, E, Takasugi, A, Obata, R, Ishikawa, Y, Umezawa, K, Nishiyama, S
Bioorg. Med. Chem. Lett.
19
(
18
)
5383
-
5386
2009年9月
-
A synthetic study on gymnastatins F and Q: the tandem Michael and aldol reaction approach
査読
Kyoko Murayama, Takamasa Tanabe, Yuichi Ishikawa, Kensuke Nakamura, Shigeru Nishiyama
TETRAHEDRON LETTERS
50
(
26
)
3191
-
3194
2009年7月
-
Total synthesis of (±)-megistophylline I
査読
Nishihama, Y, Ishikawa, Y, Nishiyama, S
Tetrahedron Lett.
50
(
23
)
2801
-
2804
2009年6月
-
Synthesis and biological evaluation on novel analogs of 9-methylstreptimidone, an inhibitor of NF-kappa B
査読
Yuichi Ishikawa, Miyuki Tachibana, Chino Matsui, Rika Obata, Kazuo Umezawa, Shigeru Nishiyama
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
19
(
6
)
1726
-
1728
2009年3月
-
Synthesis of a spiroacetal moiety of antitumor antibiotic ossamycin by anodic oxidation
査読
Eriko Honjo, Noriki Kutsumura, Yuichi Ishikawa, Shigeru Nishiyama
TETRAHEDRON
64
(
40
)
9495
-
9506
2008年9月
-
Synthesis and biological assessment of hemiacetal spiro derivatives towards development of efficient chemotherapeutic agent
査読
Takahisa Ogamino, Sayo Ohnishi, Yuichi Ishikawa, Takeshi Sugai, Rika Obata, Shigeru Nishiyama
SCIENCE AND TECHNOLOGY OF ADVANCED MATERIALS
7
(
2
)
175
-
183
2006年3月
-
The first total synthesis of SB87-Cl and pestalone, novel bioactive benzophenone natural products
査読
D Iijima, D Tanaka, M Hamada, T Ogamino, Y Ishikawa, S Nishiyama
TETRAHEDRON LETTERS
45
(
28
)
5469
-
5471
2004年7月
-
The first total synthesis and absolute stereochemistry of plakortone G from the Jamaican sponge Plakortis sp.
査読
S Kowashi, T Ogamino, J Kamei, Y Ishikawa, S Nishiyama
TETRAHEDRON LETTERS
45
(
22
)
4393
-
4396
2004年5月
-
Synthesis of the BCD ring system of azaspiracid: Construction of the trispiro ring structure by the thioether approach
査読
Yuichi Ishikawa, Shigeru Nishiyama
Tetrahedron Letters
45
(
2
)
351
-
354
2004年1月
-
Synthesis of (±)-pyrano-naphthoquinone derivatives, a Cdc25A phosphatase inhibitor
査読
Shimbashi, A, Ishikawa, Y, Nishiyama, S
Tetrahedron Lett.
45
(
5
)
939
-
941
2004年1月
-
Electrochemical synthesis of spiroisoxazole derivatives and its application to natural products
査読
T Ogamino, Y Ishikawa, S Nishiyama
HETEROCYCLES
61
73
-
+
2003年12月
-
Biological Activities of α-Mangostin Derivatives against Acidic Sphingomyelinase
査読
Hamada, M, Iikubo, K, Ishikawa, Y, Ikeda, A, Umezawa, K, Nishiyama, S
Bioorg. Med. Chem. Lett.
13
(
19
)
3151
-
3153
2003年10月
-
The first direct synthesis of α-mangostin, a potent inhibitor of the acidic sphingomyelinase
査読
Iikubo, K, Ishikawa, Y, Ando, N, Umezawa, K, Nishiyama, S
Tetrahedron Lett.
43
(
2
)
291
-
293
2002年1月
-
(+)-3-{(4S,5S)-5-[1,1-dimethyl-2-(phenylthio)ethyl]-2,2-dimethyl-1,3-dioxolan-4-yl}prop-2-yn-1-ol
査読
H Hosomi, S Ohba, K Ohmori, T Obitsu, Y Ogawa, Y Ishikawa, S Yamamura, S Nishiyama
ACTA CRYSTALLOGRAPHICA SECTION C-CRYSTAL STRUCTURE COMMUNICATIONS
56
E142
-
E143
2000年4月
-
(-)-(3S)-4-(2-{[4,4-dimethoxy-6-(benzyloxymethyl) perhydropyran-2-yl]methyl}-1,3-dithian-2-yl)-4-methyl-3-(1,1,2,2-tetramethyl-1-silapropoxy)-pentan-1-ol
査読
H Hosomi, S Ohba, K Ohmori, T Obitsu, Y Ogawa, Y Ishikawa, S Yamamura, S Nishiyama
ACTA CRYSTALLOGRAPHICA SECTION C-CRYSTAL STRUCTURE COMMUNICATIONS
56
E140
-
E141
2000年4月
-
Total synthesis of bryostatin 3
査読
K Ohmori, Y Ogawa, T Obitsu, Y Ishikawa, S Nishiyama, S Yamamura
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
39
(
13
)
2290
-
2294
2000年
