担当区分：責任著者   記述言語：英語   掲載種別：研究論文（学術雑誌）  

添付ファイル： s12663-024-02397-w.pdf

researchmap

担当区分：筆頭著者,　最終著者   記述言語：英語   掲載種別：研究論文（学術雑誌）  

添付ファイル： MFT.pdf

researchmap

担当区分：筆頭著者,　責任著者   記述言語：英語   掲載種別：研究論文（学術雑誌）  

researchmap

担当区分：責任著者   記述言語：英語   掲載種別：研究論文（学術雑誌）  

researchmap

担当区分：筆頭著者,　責任著者   記述言語：英語   掲載種別：研究論文（学術雑誌）  

researchmap

記述言語：英語   掲載種別：研究論文（学術雑誌）  

添付ファイル： j.sjcm.20241304.11.pdf

researchmap

担当区分：筆頭著者,　責任著者   記述言語：英語   掲載種別：研究論文（学術雑誌）  

添付ファイル： 1-s2.0-S1991790224002095-main.pdf

researchmap

担当区分：責任著者   記述言語：英語   掲載種別：研究論文（学術雑誌）  

添付ファイル： 1-s2.0-S1991790224002277-main.pdf

researchmap

担当区分：責任著者   記述言語：英語   掲載種別：研究論文（学術雑誌）  

添付ファイル： sugiyama-et-al-2022-submandibular-gland-mucocele-masquerading-as-plunging-ranula.pdf

researchmap

担当区分：責任著者   記述言語：英語   掲載種別：研究論文（学術雑誌）  

添付ファイル： ishikawa-et-al-2022-a-submandibular-mass-with-cystic-component.pdf

researchmap

担当区分：責任著者   記述言語：英語   掲載種別：研究論文（学術雑誌）  

添付ファイル： 1-s2.0-S1991790223003859-main.pdf

researchmap

担当区分：筆頭著者,　責任著者   記述言語：英語   掲載種別：研究論文（学術雑誌）  

添付ファイル： 1-s2.0-S1991790223003896-main.pdf

researchmap

担当区分：筆頭著者,　責任著者   記述言語：英語   掲載種別：研究論文（学術雑誌）  

添付ファイル： JOMSMP.pdf

researchmap

担当区分：責任著者   記述言語：英語   掲載種別：研究論文（学術雑誌）  

添付ファイル： 67_JPR_D_22_00225.pdf

researchmap

担当区分：筆頭著者,　責任著者   記述言語：英語   掲載種別：研究論文（学術雑誌）  

添付ファイル： Intraoral approach SMG flap.pdf

researchmap

記述言語：英語   掲載種別：研究論文（学術雑誌）  

添付ファイル： Oral Science International - 2023 - Koizumi.pdf

researchmap

担当区分：責任著者   記述言語：英語   掲載種別：研究論文（学術雑誌）  

添付ファイル： Midline mucocele.pdf

researchmap

担当区分：責任著者   記述言語：英語   掲載種別：研究論文（学術雑誌）  

添付ファイル： Pathological fractures.pdf

researchmap

担当区分：責任著者   記述言語：英語   掲載種別：研究論文（学術雑誌）  

添付ファイル： BCA palate.pdf

researchmap

担当区分：責任著者   記述言語：英語   掲載種別：研究論文（学術雑誌）  

添付ファイル： Simple method anglewider.pdf

researchmap

担当区分：筆頭著者,　責任著者   記述言語：英語   掲載種別：研究論文（学術雑誌）  

添付ファイル： Endoscope IVRO.pdf

researchmap

担当区分：責任著者   記述言語：英語   掲載種別：研究論文（学術雑誌）  

添付ファイル： Transantral apicoectomy.pdf

researchmap

担当区分：責任著者   記述言語：英語   掲載種別：研究論文（学術雑誌）  

添付ファイル： Compression method ND.pdf

researchmap

担当区分：責任著者   記述言語：英語   掲載種別：研究論文（学術雑誌）  

researchmap

担当区分：筆頭著者,　責任著者   記述言語：英語   掲載種別：研究論文（学術雑誌）  

添付ファイル： Endoscopically-assisted intraoral resection of osteochondroma of the mandibular condyle with a piezoelectric surgical device (1).pdf

researchmap

記述言語：英語   掲載種別：研究論文（学術雑誌）  

添付ファイル： 1-s2.0-S1010518223001506-main.pdf

researchmap

担当区分：責任著者   記述言語：英語   掲載種別：研究論文（学術雑誌）  

researchmap

記述言語：英語   掲載種別：研究論文（学術雑誌）  

添付ファイル： ijms-24-15618.pdf

researchmap

記述言語：英語   掲載種別：研究論文（学術雑誌）  

添付ファイル： a_novel_orthognathic_surgery_with_a.41.pdf

researchmap

担当区分：筆頭著者,　責任著者   記述言語：英語   掲載種別：研究論文（学術雑誌）  

添付ファイル： 1-s2.0-S1991790223002088-main.pdf

researchmap

担当区分：筆頭著者,　責任著者   記述言語：英語   掲載種別：研究論文（学術雑誌）  

添付ファイル： 1-s2.0-S1991790223002271-main.pdf

researchmap

記述言語：英語   掲載種別：研究論文（学術雑誌）  

添付ファイル： 67_JPR_D_22_00225.pdf

researchmap

担当区分：筆頭著者,　責任著者   記述言語：英語   掲載種別：研究論文（学術雑誌）  

添付ファイル： 1-s2.0-S2772906023000420-main.pdf

researchmap

担当区分：筆頭著者,　責任著者   記述言語：英語   掲載種別：研究論文（学術雑誌）  

添付ファイル： s12262-022-03595-x.pdf

researchmap

記述言語：英語   掲載種別：研究論文（学術雑誌）  

添付ファイル： biomimetics-08-00376.pdf

researchmap

担当区分：筆頭著者,　責任著者   記述言語：英語   掲載種別：研究論文（学術雑誌）  

添付ファイル： Metastatic angiosarcoma.pdf

researchmap

記述言語：英語   掲載種別：研究論文（学術雑誌）  

添付ファイル： 090030288.pdf

researchmap

担当区分：筆頭著者,　責任著者   記述言語：英語   掲載種別：研究論文（学術雑誌）  

添付ファイル： s12262-022-03431-2.pdf

researchmap

担当区分：筆頭著者,　責任著者   記述言語：英語   掲載種別：研究論文（学術雑誌）  

添付ファイル： Mucocele.pdf

researchmap

担当区分：筆頭著者,　責任著者   記述言語：英語   掲載種別：研究論文（学術雑誌）  

添付ファイル： Multiple_Schwannomas_Arising_in_the_Midline_Space.105.pdf

researchmap

担当区分：筆頭著者,　責任著者   記述言語：英語   掲載種別：研究論文（学術雑誌）  

添付ファイル： Huge_Submandibular_Gland_Mucocele_With_Diagnostic.82.pdf

researchmap

担当区分：筆頭著者,　責任著者   記述言語：英語   掲載種別：研究論文（学術雑誌）  

添付ファイル： 1-s2.0-S1879729622000059-main.pdf

researchmap

記述言語：英語   掲載種別：研究論文（学術雑誌）  

添付ファイル： Clinical_Anatomy_of_Feeding_Artery_of_the.68.pdf

researchmap

担当区分：筆頭著者,　責任著者   記述言語：英語   掲載種別：研究論文（学術雑誌）  

添付ファイル： 1-s2.0-S1879729622000072-main.pdf

researchmap

担当区分：筆頭著者,　責任著者   記述言語：英語   掲載種別：研究論文（学術雑誌）  

添付ファイル： 1-s2.0-S1879729621002635-main.pdf

researchmap

担当区分：責任著者   記述言語：英語   掲載種別：研究論文（学術雑誌）  

添付ファイル： SLNB.pdf

researchmap

担当区分：筆頭著者,　責任著者   記述言語：英語   掲載種別：研究論文（学術雑誌）  

添付ファイル： Schwannoma molar.pdf

researchmap

担当区分：筆頭著者,　責任著者   記述言語：英語   掲載種別：研究論文（学術雑誌）  

添付ファイル： Intraoral_Styloidectomy_Using_an_Endoscope_With.51.pdf

researchmap

担当区分：責任著者   記述言語：英語   掲載種別：研究論文（学術雑誌）  

添付ファイル： 1-s2.0-S2468785521001919-main.pdf

researchmap

担当区分：筆頭著者,　責任著者   記述言語：英語   掲載種別：研究論文（学術雑誌）  

添付ファイル： Anatomical_Relationship_Between_the_Lingual_Nerve.56.pdf

researchmap

記述言語：英語   掲載種別：研究論文（学術雑誌）  

添付ファイル： lrb.2021.0040 (1).pdf

researchmap

記述言語：英語   掲載種別：研究論文（学術雑誌）  

researchmap

担当区分：筆頭著者,　責任著者   記述言語：英語   掲載種別：研究論文（学術雑誌）  

添付ファイル： Dermoid cyst.pdf

researchmap

担当区分：責任著者   記述言語：英語   掲載種別：研究論文（学術雑誌）  

添付ファイル： Malignant transformation.pdf

researchmap

担当区分：筆頭著者,　責任著者   記述言語：英語   掲載種別：研究論文（学術雑誌）  

添付ファイル： Lipoma.pdf

researchmap

担当区分：責任著者   記述言語：英語   掲載種別：研究論文（学術雑誌）  

添付ファイル： 0145561320937080.pdf

researchmap

担当区分：責任著者   記述言語：英語   掲載種別：研究論文（学術雑誌）  

添付ファイル： 0145561320935838.pdf

researchmap

記述言語：英語   掲載種別：研究論文（学術雑誌）  

添付ファイル： 10.1177_2050313x211048279.pdf

researchmap

担当区分：責任著者   記述言語：英語   掲載種別：研究論文（学術雑誌）  

添付ファイル： dmfr.20200333.pdf

researchmap

担当区分：責任著者   記述言語：英語   掲載種別：研究論文（学術雑誌）  

添付ファイル： Sugiyama2021_Article_SentinelLymphNodeMappingOfClin.pdf

researchmap

担当区分：責任著者   記述言語：英語   掲載種別：研究論文（学術雑誌）  

添付ファイル： 1-s2.0-S1991790220302002-main.pdf

researchmap

担当区分：責任著者   記述言語：日本語   掲載種別：研究論文（学術雑誌）  

添付ファイル： 1-s2.0-S2212555820301629-main.pdf

researchmap

記述言語：英語   掲載種別：研究論文（学術雑誌）  

添付ファイル： Temporomandibular joint stability after two types of maxillary impaction surgery in patients with skeletal class II open bite due to condylar.pdf

researchmap

記述言語：英語   掲載種別：研究論文（学術雑誌）  

添付ファイル： s13256-020-02584-6.pdf

researchmap

担当区分：責任著者   記述言語：英語   掲載種別：研究論文（学術雑誌）  

添付ファイル： 1-s2.0-S2212555820301812-main.pdf

researchmap

記述言語：英語   掲載種別：研究論文（学術雑誌）  

添付ファイル： Yanagida2021_.pdf

researchmap

担当区分：責任著者   記述言語：英語   掲載種別：研究論文（学術雑誌）  

添付ファイル： 1-s2.0-S2212555820302118-main.pdf

researchmap

担当区分：筆頭著者,　責任著者   記述言語：英語   掲載種別：研究論文（学術雑誌）  

添付ファイル： PA.pdf

researchmap

担当区分：責任著者   記述言語：英語   掲載種別：研究論文（学術雑誌）  

添付ファイル： Delayed infection.pdf

researchmap

担当区分：筆頭著者,　責任著者   記述言語：英語   掲載種別：研究論文（学術雑誌）  

添付ファイル： Iwai2021_Article_ActinomycoticOsteomyelitisWith.pdf

researchmap

担当区分：責任著者   記述言語：英語   掲載種別：研究論文（学術雑誌）  

添付ファイル： Minamiyama2021_Article_SchwannomaArisingFromTheSublin.pdf

researchmap

担当区分：責任著者   記述言語：英語   掲載種別：研究論文（学術雑誌）  

添付ファイル： Oncocytoma.pdf

researchmap

担当区分：筆頭著者,　責任著者   記述言語：英語   掲載種別：研究論文（学術雑誌）  

researchmap

担当区分：筆頭著者,　責任著者   記述言語：英語   掲載種別：研究論文（学術雑誌）  

添付ファイル： 1-s2.0-S2468785520300458-main.pdf

researchmap

担当区分：筆頭著者,　責任著者   記述言語：英語   掲載種別：研究論文（学術雑誌）  

researchmap

記述言語：英語   掲載種別：研究論文（学術雑誌）  

researchmap

担当区分：責任著者   記述言語：英語   掲載種別：研究論文（学術雑誌）  

添付ファイル： 1-s2.0-S2212555820301344-main.pdf

researchmap

記述言語：英語   掲載種別：研究論文（学術雑誌）  

researchmap

担当区分：筆頭著者,　責任著者   記述言語：英語   掲載種別：研究論文（学術雑誌）  

添付ファイル： Oral stings.pdf

researchmap

記述言語：英語   掲載種別：研究論文（学術雑誌）  

researchmap

担当区分：責任著者   記述言語：英語   掲載種別：研究論文（学術雑誌）  

researchmap

記述言語：英語   掲載種別：研究論文（学術雑誌）  

添付ファイル： 1-s2.0-S0901502719314110-main.pdf

researchmap

担当区分：責任著者   記述言語：英語   掲載種別：研究論文（学術雑誌）  

researchmap

記述言語：英語   掲載種別：研究論文（学術雑誌）  

添付ファイル： 1-s2.0-S175161611931313X-main.pdf

researchmap

担当区分：責任著者   記述言語：英語   掲載種別：研究論文（学術雑誌）  

添付ファイル： 1-s2.0-S1010518220300159-main.pdf

researchmap

記述言語：英語   掲載種別：研究論文（学術雑誌）  

添付ファイル： ijms-21-00660.pdf

researchmap

記述言語：英語   掲載種別：研究論文（学術雑誌）  

添付ファイル： s40644-019-0258-9.pdf

researchmap

記述言語：英語   掲載種別：研究論文（学術雑誌）  

添付ファイル： 1-s2.0-S2212555819300985-main.pdf

researchmap

記述言語：英語   掲載種別：研究論文（学術雑誌）  

添付ファイル： SwallowingFunctionInAdvancedTo.pdf

researchmap

記述言語：英語   掲載種別：研究論文（学術雑誌）  

添付ファイル： article.pdf

researchmap

記述言語：英語   掲載種別：研究論文（学術雑誌）  

添付ファイル： Hemangiopericytoma.pdf

researchmap

記述言語：英語   掲載種別：研究論文（学術雑誌）  

添付ファイル： Head Neck - 2019 - Hayashi - Prognostic factors and treatment outcomes of advanced maxillary gingival squamous cell.pdf

researchmap

記述言語：英語   掲載種別：研究論文（学術雑誌）  

添付ファイル： Limphoedema.pdf

DOI： 10.1038/s41598-019-44735-w

PubMed

researchmap

記述言語：英語   掲載種別：研究論文（学術雑誌）  

添付ファイル： Int J Radiat Res-v17n2p283-en.pdf

researchmap

記述言語：英語   掲載種別：研究論文（学術雑誌）  

AIM: We aimed to retrospectively investigate the outcomes and pathological effects of retrograde superselective intra-arterial chemoradiotherapy (IACRT) combined with hyperthermia on metastatic lymph nodes of patients with oral squamous cell carcinoma. PATIENTS AND METHODS: Patients with lymph node metastasis from oral cancer were treated with IACRT using cisplatin plus docetaxel combined with hyperthermia prior to surgical removal 8 weeks after completion of IACRT and hyperthermia. The locoregional control and overall survival rates were calculated using the Kaplan-Meier method. RESULTS: A total of 35 patients received the combination therapy of whom 26 received it as definitive treatment and in the rest, it was administered as preoperative treatment. The 5-year locoregional control and overall survivaI rates were 95.6% and 80.2% in the definitive-treatment group, and 100% and 66.6% in the preoperative-treatment group, respectively. CONCLUSION: The combination therapy provided good outcomes in patients with lymph node metastases from advanced oral cancer.

DOI： 10.21873/anticanres.13250

PubMed

researchmap

記述言語：英語   掲載種別：研究論文（学術雑誌）  

We herein report a case of squamous cell carcinoma of the buccal mucosa with N3 cervical lymph node metastasis in a 63-year-old man. The patient was treated with combination therapy comprising radiotherapy (2 Gy/day, total of 70 Gy), superselective intra-arterial chemotherapy via a superficial temporal artery (docetaxel, total of 70 mg/m2 and cisplatin, total of 175 mg/m2), cetuximab (initial dose of 400 mg/m2 with subsequent weekly doses of 250 mg/m2 intravenously), and four sessions of hyperthermia for cervical lymph node metastases. The patient responded well to the therapy, with a complete response of the primary tumor. Radical neck dissection was performed with reconstructive surgery, including resection of the overlying skin. A pathologic complete response was achieved for the N3 and all other cervical lymph node metastases. The patient showed no evidence of recurrence in the 3 years following treatment. Based on the findings in the present case, the use of retrograde superselective intra-arterial chemoradiotherapy combined with hyperthermia and cetuximab seems to be a promising modality for patients with N3 cervical lymph node metastasis of oral cancer.

添付ファイル： Sakuma2019_Article_RetrogradeSuperselectiveIntra-.pdf

DOI： 10.1007/s11282-018-0319-y

PubMed

researchmap

記述言語：英語   掲載種別：研究論文（学術雑誌）  

添付ファイル： 40036_CE[Ra1]_F(KM)_PF1(AB_SL)_PN(SL).pdf

researchmap

記述言語：英語   掲載種別：研究論文（学術雑誌）  

添付ファイル： CRT mandible.pdf

researchmap

記述言語：英語   掲載種別：研究論文（学術雑誌）  

添付ファイル： Airway.pdf

DOI： 10.2147/TCRM.S180797

PubMed

researchmap

記述言語：英語   掲載種別：研究論文（学術雑誌）  

添付ファイル： Dentigerous cyst.pdf

researchmap

記述言語：英語   掲載種別：研究論文（学術雑誌）  

researchmap

記述言語：英語   掲載種別：研究論文（学術雑誌）  

添付ファイル： medicina-54-00052.pdf

researchmap

記述言語：英語   掲載種別：研究論文（学術雑誌）  

添付ファイル： Implant failure.pdf

researchmap

記述言語：英語   掲載種別：研究論文（学術雑誌）  

添付ファイル： Solitary osteoma.pdf

researchmap

記述言語：英語   掲載種別：研究論文（学術雑誌）  

Introduction: Although chemoradiotherapy (CRT) for oral squamous cell carcinoma (SCC) has been shown to preserve organ function and improve cosmetic results, site-specific data, especially mandible, are limited. The aim of this study was to evaluate the predictability of 18F-fluorodeoxyglucose positron emission tomography/computed tomography (FDG-PET/CT) on response to super-selective intra-arterial CRT for advanced SCC of the mandible. Methods: Fifteen patients with advanced SCC of the mandible underwent super-selective intra-arterial CRT followed by radical resection. Maximum standardized uptake value (SUVmax) of the mandibular lesion was evaluated with FDG-PET/CT before and after CRT. The SUVmax before and after CRT was defined as pre-SUVmax and post-SUVmax, respectively. The difference between pre- and post-SUVmax was calculated as SUVmax reduction rate to evaluate treatment response of the mandibular lesion. Each SUVmax reduction rate and surgical specimen of the corresponding lesion was analyzed to evaluate an accuracy of the modality for predicting pathological response. Results: The median of pre-SUVmax was significantly lower than that of post-SUVmax (p = 0.001). Of the 15 patients, 6 had a pathological complete response (pCR) and 9 had a non-pCR. Neither pCR patients nor non-pCR patients showed significant difference of the median of SUVmax between pre- and post-CRT (pre-CRT p = 0.099 post-CRT p =0.074). The SUVmax reduction rate in patients with pCR was significantly higher than that with non-pCR (p = 0.002). Receiver operating characteristic analysis revealed that the optimal cut-off point of the reduction rate was 64.7%, with 83% sensitivity and 100% specificity. Conclusions: These results concluded that SUVmax reduction rate can predict pathological complete response of preoperative super-selective intra-arterial CRT for advanced SCC of the mandible.

添付ファイル： PET Mandible.pdf

DOI： 10.1016/j.jbo.2018.02.001

PubMed

researchmap

担当区分：責任著者   記述言語：英語   掲載種別：研究論文（学術雑誌）   出版者・発行元：Blackwell Publishing Ltd  

Oral surgeons rarely experience accidental displacement of a mandibular impacted third molar into adjacent anatomical spaces as a complication. As any displaced third molar or its root is commonly removed at the time of displacement or within several weeks of the extraction, delayed removal several years after initial extraction is extremely rare. We report here accidental displacement of a mandibular third molar root into the sublingual space and a 5-year delay in its removal. A 42-year-old woman presented to our department with pain and swelling in the lingual aspect of the left mandible. Computed tomography revealed a 15 × 11 × 9 mm lesion, with a similar density to that of the surrounding bone and involving the lingual cortex of the left mandible. A yellowish-white hard tissue lesion was protruding from the lingual mucosa of the left mandibular ramus. The patient had undergone removal of a left impacted mandibular third molar at a private dental clinic 5 years earlier and we diagnosed the lesion as a remnant third molar root. The patient had not been informed by her dentist of accidental displacement of the tooth into the sublingual space after crown removal. After complete alleviation of inflammation, the patient underwent intraoral removal of the root under general anaesthesia. After elevating the lingual mucoperiosteal flap from the mandibular ramus to the premolar region, the root was easily removed using an elevator and forceps. Her postoperative course was uneventful and there were no complications such as lingual nerve injury.

添付ファイル： Yamashita_et_al-2018-Oral_Surgery.pdf

DOI： 10.1111/ors.12303

Scopus

researchmap

担当区分：責任著者   記述言語：英語   掲載種別：研究論文（学術雑誌）   出版者・発行元：Elsevier Ltd  

Osteomas are benign, slow-growing osteogenic tumors that consist of compact or cancellous bone. They sometimes arise from the craniomaxillofacial region. Among the peripheral, central, and extraskeletal types, peripheral osteomas arise from the periosteum, usually as unilateral, pedunculated, mushroom-like masses. Here, we report an unusual peripheral osteoma arising from the lateral surface of the mandibular ramus. A 57-year-old woman with a mass at the left mandibular ramus was referred to us. The hard and immobile mass had been growing for 15 years, and she had facial asymmetry. She had no trismus, temporomandibular joint dysfunction, previous facial trauma, or infection. Computed tomography showed a mushroom-like lesion (21.1 × 13.4 × 13.1 mm) arising from the lateral surface of the left mandibular ramus. Clinical diagnosis was peripheral osteoma. The lesion was removed using rotary instruments and a chisel through an intraoral approach under general anesthesia. The lesion had intruded into the masseter muscle. Pathological diagnosis was compact osteoma. The postoperative course was uneventful and there has been no recurrence 1.5 years after surgery.

添付ファイル： 1-s2.0-S2212555818300115-main.pdf

DOI： 10.1016/j.ajoms.2018.02.004

Scopus

researchmap

記述言語：英語   掲載種別：研究論文（学術雑誌）  

添付ファイル： honda k.pdf

researchmap

記述言語：英語   掲載種別：研究論文（学術雑誌）  

OBJECTIVES: To evaluate the therapeutic results and rate of organ preservation in patients with squamous cell carcinoma of the tongue treated with retrograde superselective intra-arterial chemoradiotherapy. MATERIALS AND METHODS: Between June 2006 and June 2015, 118 patients with tongue cancer were treated with intra-arterial chemoradiotherapy. Treatment consisted of radiotherapy (total 50-70 Gy) and daily concurrent intra-arterial chemotherapy (docetaxel, total 50-70 mg/m2; cisplatin, total 125-175 mg/m2) for 5-7 weeks. Locoregional control and overall survival rates were calculated by the Kaplan-Meier method. Cox's proportional hazards model was used for both univariate and multivariate analyses. RESULTS: The median follow-up for all patients was 38.5 months (range, 3-129 months). After intra-arterial chemoradiotherapy, primary site complete response was achieved in 113 (95.8%) of 118 cases. Three-year locoregional control and overall survival rates were 80.3% and 81.5%, respectively. Grade 3 or 4 toxicities included neutropenia in 16.1% and mucositis in 87.3%. Grade 3 toxicities included anemia in 12.7%, thrombocytopenia in 3.4%, nausea/vomiting in 3.4%, dermatitis in 45.7%, dysphagia in 74.6%, and fever in 2.5% of patients. Late toxicity consisting of grade 3 osteoradionecrosis of the jaw occurred in 4.2% of patients. On univariate analysis, T stage and overall stage were significantly associated with locoregional control, and N stage and overall stage were significantly associated with overall survival. On multivariate analysis, the only significant predictor of overall survival was overall stage classification. CONCLUSION: Retrograde superselective intra-arterial chemoradiotherapy for tongue cancer provided good overall survival and locoregional control.

添付ファイル： CRT.pdf

DOI： 10.1016/j.oraloncology.2018.02.002

PubMed

researchmap

担当区分：筆頭著者,　責任著者   記述言語：英語   掲載種別：研究論文（学術雑誌）  

添付ファイル： fish bone.pdf

DOI： 10.1016/j.anl.2017.03.010

PubMed

researchmap

記述言語：英語   掲載種別：研究論文（学術雑誌）  

添付ファイル： The_Holographic_Human_for_Surgical_Navigation_using_Microsoft_HoloLens.pdf

researchmap

記述言語：英語   掲載種別：研究論文（学術雑誌）   出版者・発行元：Society of Hard Tissue Regenerative Biology  

This study aimed to evaluate the mechanical stress on resected mandibular bone against occlusal force using dental implant without any bone grafting by finite element analysis to reduce the risk of the bone fracture. A model of marginal resection of the symphysis of the mandible, in which the bone height of the region was 5, 10 or 15 mm, was prepared. Two, four, or six implant-supported fixed prostheses (superstructure) or overdenture were set up in the model and loaded with 500N of occlusal force. The von Mises stress on the resected region was the highest when two implants were bilaterally placed at positions closest to the resected region. The von Mises stress value on the resected region could be high enough to induce the bone fracture. The mechanical stress was reduced up to &lt
50 % by adding implant at posterior position and connecting all implants. The presence of superstructure on 4 or 6 implants significantly decreased the von Mises stress when the residual bone height was 10 or 15 mm. Use of 6 implants showed no significant advantage at the stress reduction compared to use of 4 implants. When the residual bone height was 5 mm, reinforcement of the residual bone or bone graft should be considered to avoid the bone fracture. Although the present results were obtained under restrictive conditions, the number of implant, implant position, and prostheses style could reduce the von Mises stress and the risk of bone fracture on the resected region.

添付ファイル： 27_11.pdf

DOI： 10.2485/jhtb.27.11

Scopus

researchmap

記述言語：英語   掲載種別：研究論文（学術雑誌）   出版者・発行元：LIPPINCOTT WILLIAMS & WILKINS  

Free tissue transfer is the preferred reconstruction option inmost major head and neck reconstructions. The pectoralis major muscle musculocutaneous (PMMC) flap is commonly used in salvage of necrotic free flaps and is the first choice for patients who are not candidates for free flaps. The lateral thoracic artery (LTA), which is thought to contribute to blood perfusion of the inferior and lateral mammary area, is not preserved in a conventionally harvested PMMC flap. With regard to blood supply, it has been suggested that the LTA should be preserved, in addition to the pectoral branch of the thoracoacromial artery, when a skin island is designed in the lower chest to attain a pedicle length sufficient for head and neck reconstruction. However, an effect on hemodynamic improvement using the LTA has not been shown quantitatively. In this study, we examined 8 patients with oral cancer who underwent reconstruction procedures with a bipedicle PMMC flap that included the LTA, in addition to the thoracoacromial artery. Intraoperative indocyanine green angiography was performed to examine circulation to the PMMC flap with or without LTA clamping after harvesting. After image processing, data were analyzed using a new quantitative perfusion assessment system with parameters that we recently established for assessment of peripheral arterial disease of the lower limbs. All patients had good clinical courses with whole-flap survival, no vascular insufficiency of the skin island, and no fistula formation. Intraoperative indocyanine green angiography showed an increased inflow rate into the skin island in an LTA-declamped condition in all cases, implying that the preserved LTA increased the blood supply to skin islands in the pectoralis major muscle. We conclude that preserving the LTA in a PMMC flap can increase blood perfusion and stabilize the vascularity of the flap, making the reconstruction more effective and reliable than with use of a conventionally harvested flap. Therefore, it is worthwhile to preserve the LTA as a major contributor to a lateral and distal PMMC flap.

添付ファイル： ICG PMMC.pdf

DOI： 10.1097/SAP.0000000000001123

Web of Science

PubMed

researchmap

記述言語：英語   掲載種別：研究論文（学術雑誌）   出版者・発行元：ELSEVIER SCIENCE BV  

The external jugular vein (EJV) is often utilized as a recipient vein in the head and neck during microsurgical reconstruction or for central venous catheterization. However, there are few studies about its anatomical variations. Knowledge of these variations is important for clinicians as well as surgeons. We report here an empty fenestration of the EJV, an extremely rare variant, observed during modified radical neck dissection. (C) 2017 Anatomical Society of India. Published by Elsevier, a division of RELX India, Pvt. Ltd. All rights reserved.

添付ファイル： Fenestration.pdf

DOI： 10.1016/j.jasi.2017.10.005

Web of Science

researchmap

記述言語：英語   掲載種別：研究論文（学術雑誌）  

添付ファイル： dentistry-oraldisorders-therapy87.pdf

researchmap

担当区分：責任著者   記述言語：英語   掲載種別：研究論文（学術雑誌）   出版者・発行元：Elsevier Ltd  

Objective As the first step in sialendoscopy, the orifice of the salivary duct is progressively dilated using different sized salivary probes before the sialendoscope is inserted. However, the procedure can be challenging as surgeons may lose the duct orifice and find it difficult to re-identify after each probe change. To overcome this problem, we previously reported a simple technique using a guidewire, but a more cost-effective and time-saving approach is needed. We describe a modified method for simple dilatation of the papilla orifice to introduce the sialendoscope easily into the ductal lumen. Methods A 24 G angiocatheter and a 0.5-mm-diameter salivary or lacrimal probe is prepared preoperatively. The tip of the angiocatheter (3.3–0.7 mm outer diameter) is cut and the probe is threaded into the tapered catheter. On identifying the duct orifice by pressing the salivary gland, they are inserted together into the duct orifice. Only the catheter is advanced into the duct along the probe to dilate the orifice. The orifice can be easily dilated without losing the papilla entrance. After removing the catheter, a sialoendoscope can be inserted easily into the duct. Results We performed more than 100 procedures using this modified method and the sialendoscope could be inserted into the duct within 10 s after probe insertion into the orifice. Conclusion This method offers simple dilatation of the papilla orifice to introduce the sialendoscope.

添付ファイル： Sakuma JOMSMP.pdf

DOI： 10.1016/j.ajoms.2017.05.003

Scopus

researchmap

記述言語：英語   掲載種別：研究論文（学術雑誌）  

添付ファイル： A-Simple-Self-Made-Scale.pdf

researchmap

担当区分：筆頭著者,　責任著者   記述言語：英語   掲載種別：研究論文（学術雑誌）   出版者・発行元：SPRINGER  

Aneurysms of the external carotid artery and its branches are rare, and usually occur in the more superficial branches. Lingual artery (LA) aneurysms are particularly rare, and pseudoaneurysms are associated with trauma, infection, and surgical intervention. Only a few cases of idiopathic LA aneurysms have been reported in the English literature. LA aneurysms can be fatal if they are not recognized and treated. Here, we report a case of bilateral idiopathic aneurysms of the LA identified by three-dimensional (3D) computed tomography angiography (CTA). An 80-year-old man with right tongue cancer (T2N0M0) and left tongue leukoplakia was referred to our department for treatment. He had no previous history of trauma, infection, surgery, or aneurysm in the oral and maxillofacial region. CTA with 3D reconstruction showed right and left aneurysms of the LA, with sizes of 2.4 x 2.3 x 2.1 mm and 3.4 x 3.2 x 2.5 mm, respectively. The patient underwent bilateral partial glossectomy under general anesthesia without intervention for the aneurysms, and the post-operative course was uneventful. A radiological follow-up has been performed regularly for the small unruptured aneurysms.

添付ファイル： BLAA.pdf

DOI： 10.1007/s11282-016-0255-7

Web of Science

researchmap

記述言語：英語   掲載種別：研究論文（学術雑誌）   出版者・発行元：BIOMED CENTRAL LTD  

Background: We present the cases of 2 patients with invasive thyroid cancer, who underwent reconstructive surgery using a deltopectoral flap. Although the overall rate of extrathyroidal extension in patients with thyroid cancer is quite low, skin invasion is the most common pattern observed. Reconstructive surgery, involving local skin flaps, is required in these patients. The deltopectoral flap relies on the blood supply from intercostal perforators of the internal thoracic artery and usually requires skin grafting to the donor site. The internal thoracic artery is rarely sacrificed in these cases, even in an advanced surgery such as in patients with invasive thyroid cancer.
Case presentation: A 55-year-old man with a distended thyroid gland presented to our hospital. He underwent advanced surgery, including skin excision, because we suspected that his tumor was thyroid cancer. The defect was covered with an ipsilateral deltopectoral flap via transposition of the flap, without skin grafting. In the second case, a 67-year-old woman with thyroid cancer that metastasized to her neck lymph nodes presented to our institution. Although the ipsilateral internal thoracic artery was sacrificed near its origin during tumor resection, the deltopectoral flap was raised in the usual manner without any complications. The skin defect caused by the tumor resection was covered with the flap. The patient had an uneventful clinical course for more than 2 years of follow-up. These 2 cases show the effectiveness of using the deltopectoral flap as a reconstructive option for patients with thyroid cancer who underwent radical surgery, resulting in a skin defect. The first case shows that this flap does not always require skin grafting to the donor site. To our knowledge, the second case may be the first report of a deltopectoral flap that was safely raised and applied with resection of the bifurcation of the ipsilateral internal thoracic artery.
Conclusions: Although thyroid cancer surgery with surrounding skin excision is a rare procedure, we found that the deltopectoral flap was useful and should be the first choice for patients undergoing reconstructive surgery, whether the bifurcation of the ipsilateral internal thoracic artery is sacrificed.

添付ファイル： DP.pdf

DOI： 10.1186/s12893-017-0297-8

Web of Science

researchmap

記述言語：英語   掲載種別：研究論文（学術雑誌）  

添付ファイル： JCDR.pdf

researchmap

記述言語：英語   掲載種別：研究論文（学術雑誌）  

添付ファイル： Implant Treatment for the patients.pdf

researchmap

担当区分：責任著者   記述言語：英語   掲載種別：研究論文（学術雑誌）   出版者・発行元：Elsevier Ltd  

Objective Intraoral removal of proximal/hilar or intraglandular stones is technically difficult, because the surgical field is limited. However, intraoral removal of deep submandibular gland stones has several advantages over submandibular sialoadenectomy, including shorter operation time and better gland function. To overcome the technical difficulties associated with intraoral removal of deep submandibular gland stones, we designed a novel tongue retractor and here describe its use. Methods The tongue retractor for the intraoral removal of proximal/hilar submandibular gland stones has a wing on each side for the retraction of soft tissues. After careful dissection along Wharton's duct to the hilum of the submandibular gland, we used the new tongue retractor. Results The new tongue retractor enables the lingual soft tissues to be retracted easily and it maintains a better surgical field, compared with standard tongue retractors. For hilar/intraglandular stones in the medial portion of the submandibular gland, after dissection of the medial side of the gland, the newly designed tongue retractor provided a good surgical field for easy and reliable stone removal. Conclusion This novel tongue retractor offers a better surgical field and shorter operation time for intraoral stone removal than standard tongue retractors.

添付ファイル： Tongue retractor.pdf

DOI： 10.1016/j.ajoms.2017.03.003

Scopus

researchmap

記述言語：英語   掲載種別：研究論文（学術雑誌）   出版者・発行元：ELSEVIER SCIENCE INC  

Objective. To evaluate the therapeutic results and control of occult neck metastasis in patients with T2-4N0 oral tongue squamous cell carcinoma treated with retrograde superselective intra-arterial chemotherapy and daily concurrent radiotherapy.
Study Design. Forty-two patients with T2-4N0 tongue cancer (17 with late T2; 13 with T3; and 12 with T4a disease, M0) were treated with intra-arterial chemoradiotherapy. Treatment consisted of retrograde superselective intra-arterial chemotherapy (docetaxel 50-70 mg/m(2), cisplatin 125-175 mg/m(2)) and daily concurrent radiotherapy (50-70 Gy) for 5-7 weeks.
Results. The median follow-up for all patients was 46.5 months (range, 8-105 months). Primary-site complete response was achieved in 42 of 42 cases (100%). Three-year overall survival, progression-free survival, and local control rates were 85.0%, 77.8%, and 91.7%, respectively. Delayed neck metastasis was detected in 5 of 42 cases (11.9%). Grade 3 or 4 toxic changes included oral mucositis in 92.9%, neutropenia in 21.4%, and thrombocytopenia in 4.8%. Grade 3 toxicities included anemia in 16.7%, radiation dermatitis in 9.5%, nausea in 4.8%, and fever in 2.4%.
Conclusions. Retrograde superselective intra-arterial chemotherapy for T2-4N0 tongue cancer provided good overall survival and local control rates and was effective for occult neck metastasis.

添付ファイル： N0 IACRT.pdf

DOI： 10.1016/j.oooo.2017.02.004

Web of Science

PubMed

researchmap

記述言語：英語   掲載種別：研究論文（学術雑誌）  

添付ファイル： Hayashi 2017.pdf

DOI： 10.1186/s13014-017-0847-3

Web of Science

PubMed

researchmap

担当区分：責任著者   記述言語：英語   掲載種別：研究論文（学術雑誌）   出版者・発行元：CHURCHILL LIVINGSTONE  

The purpose of this study was to investigate the relationship between the pressure drop in the pharyngeal airway space (Delta P-PAS) and the minimum cross-sectional area (minCSA) of the pharyngeal airway before and after mandibular setback surgery using computational fluid dynamics, in order to prevent iatrogenic obstructive sleep apnoea. Eleven patients with mandibular prognathism underwent bilateral sagittal split osteotomy for mandibular setback. Three-dimensional models of the upper airway were reconstructed from preoperative and postoperative computed tomography images, and simulations were performed using computational fluid dynamics. Delta P-PAS and the minCSA of the pharyngeal airway were calculated, and the relationship between them was evaluated by non-linear regression analysis. In all cases, the minCSA was found at the level of the velopharynx. After surgery, Delta P-PAS increased significantly and the minCSA decreased significantly. The non-linear regression equation expressing the relationship between these variables was Delta P-PAS = 3.73 x minCSA(-2.06). When the minCSA was <1 cm(2), Delta P-PAS increased greatly. The results of this study suggest that surgeons should consider bimaxillary orthognathic surgery rather than mandibular setback surgery to prevent the development of iatrogenic obstructive sleep apnoea when correcting a skeletal class III malocclusion.

添付ファイル： CFD.pdf

DOI： 10.1016/j.ijom.2017.03.028

Web of Science

PubMed

researchmap

担当区分：筆頭著者,　責任著者   記述言語：英語   掲載種別：研究論文（学術雑誌）   出版者・発行元：ELSEVIER SCIENCE BV  

Variation of the branches of the external carotid artery is well known, but it is extremely rare for the occipital artery (OA) to arise from the carotid bifurcation (CB). A 73-year-old man was found to have this anatomical variation on the right side by three-dimensional CT angiography for vascular mapping of the carotid arteries before superselective intra-arterial catheterization. The OA arose from the CB and the inner diameter of the origin of the OA was 1.5 mm. The CB was located at the level of C3-C4 and 7.9 mm above the tip of the greater horn of the hyoid bone. (C) 2017 Anatomical Society of India. Published by Elsevier, a division of RELX India, Pvt. Ltd. All rights reserved.

添付ファイル： OA origin CTA.pdf

DOI： 10.1016/j.jasi.2017.05.003

Web of Science

researchmap

担当区分：責任著者   記述言語：英語   掲載種別：研究論文（学術雑誌）   出版者・発行元：CHURCHILL LIVINGSTONE  

Facial nerve paralysis (FNP) after super-selective intra-arterial chemotherapy (SSIAC) is a relatively rare local side effect of SSIAC to the maxillary artery (MA) or the middle meningeal artery (MMA). The incidence and prognosis of FNP after SSIAC in 381 patients with oral cancer (133 with catheterization of the MA, 248 without) was investigated retrospectively. Only three patients (two male and one female) had FNP, for an incidence of 0.8%. All patients with FNP had undergone catheterization of the MA, and the incidence of FNP in this group was 2.3% (3/133). One of the three patients with FNP had paralysis of the third branch of the trigeminal nerve. FNP occurred a mean of 8.7 days (range 5-11 days) after initial SSIAC, and the mean total dose of cisplatin was 55.8 mg (range 42.5-67.2 mg) and of docetaxel was 25.4 mg (range 17.0-33.6 mg). FNP resolved completely a mean of 12.7 months (range 6-19 months) after onset. Because the administration of anticancer agents via the MA or MMA carries a risk of FNP, this information will be useful when obtaining informed consent from patients before treatment.

添付ファイル： FNP.pdf

DOI： 10.1016/j.ijom.2017.01.011

Web of Science

PubMed

researchmap

担当区分：責任著者   記述言語：英語   掲載種別：研究論文（学術雑誌）   出版者・発行元：Elsevier Ltd  

Actinomycosis is often considered an affliction of the soft tissues, but in fact, the process spreads to bone in up to 15% of cases. Although Actinomyces-associated lesions in the jaw, such as radicular cyst and osteomyelitis, have been reported by many authors, there are few reports have previously described Actinomyces-associated calcification in the jaw. We report here a rare case of Actinomyces-associated calcifications around an impacted third molar of the mandible. A 76-year-old man with left mandibular pericoronitis was referred to our department. A panoramic radiograph showed alveolar bone resorption caused by severe periodontitis of the left mandibular second molar and multiple small radiopaque spots around the crown of left mandibular third molar in a radiolucent lesion. Computed tomography revealed that the lesion of the left mandibular retromolar lesion was low density, with multiple high density spots surrounding the third molar crown surface. Removal of the lesion and the left mandibular second and third molars were performed and multiple small black pieces of hard tissue were present on the crown surface of the third molar. Histopathological examination of soft tissue specimen around the third molar revealed that collagenous fibroconnective tissue infiltrated by inflammatory cells with squamous epithelium on its surface. Black hard tissue consisted of calcification and conglomerations of Actinomyces which were densely stained by hematoxylin-eosin stain were observed at the margin of the hard tissue surrounding tiny filamentous structures. The postoperative course was uneventful without need for additional antibiotics and there has been no recurrence 22 months after surgery.

添付ファイル： AM.pdf

DOI： 10.1016/j.ajoms.2016.12.004

Scopus

researchmap

担当区分：責任著者   記述言語：英語   掲載種別：研究論文（学術雑誌）   出版者・発行元：BIOMED CENTRAL LTD  

Background: Intra-arterial chemotherapy (IAC) for oral cancer can deliver a higher concentration of anticancer agent into a tumor-feeding artery than intravenous systemic chemotherapy. However, distribution of anticancer agent into several branches of the external carotid artery (ECA) in IAC has not demonstrated sufficient treatment efficacy. To improve the effectiveness of IAC, the flow distribution of anticancer agent into the branches of the ECA in several IAC methods was investigated using computational fluid dynamics (CFD).
Methods: Patient-specific three-dimensional vessel models were created from CT images of 2 patients with tongue cancer. Catheter models were combined with the vessel models. Thirty-two models were generated with varying vertical and horizontal positions of the catheter tip. With the use of a zero-dimensional resistance model of the peripheral vessel network, conventional IAC and superselective IAC were simulated in 30 and 2 models, respectively. The flow distribution of anticancer agent into the branches of the ECA was investigated in 32 models. Additionally, the blood streamline was traced from the inlet of the common carotid artery toward each outlet to examine the flow of anticancer agent in all models, and the wall shear stress of the vessel was calculated for some models.
Results: The CFD simulations could be conducted within a reasonable computational time. In several models, the anticancer agent flowed into the target artery only when the catheter tip was located below the bifurcation of the ECA and each target artery. Furthermore, the anticancer agent tended to flow into the target artery when the catheter tip was shifted toward the target artery. In all ECA branches that had flow of anticancer agent, the blood streamlines to the target arteries contacted the catheter tip. Anticancer agent flowed into only the target artery in patients' models for superselective IAC. However, high wall shear stress was observed at the target artery in one patient's model.
Conclusions: This CFD study showed that location of the catheter tip was important in controlling the anticancer agent in conventional IAC. The distribution rate of anticancer agent into the tumor-feeding artery tended to increase when the catheter tip was placed below and toward the target artery. Although superselective IAC can reliably supply anticancer agent to the target artery, high wall shear stress at the target artery can occur, depending on vessel geometry of the patient, which may cause serious complications during the treatment.

添付ファイル： BEO.pdf

DOI： 10.1186/s12938-017-0348-5

Web of Science

PubMed

researchmap

記述言語：英語   掲載種別：研究論文（学術雑誌）  

添付ファイル： 12663_2016_Article_962.pdf

researchmap

記述言語：英語   掲載種別：研究論文（学術雑誌）   出版者・発行元：Blackwell Publishing Ltd  

Third molar removal is one of the most common procedures performed by dentists and oral surgeons. Removal of maxillary third molar is associated with a lower rate of complication compared to the mandible, and maxillary tuberosity fracture or ophthalmologic complications after removal of maxillary third molar are very rare. We report maxillary tuberosity fracture and ophthalmologic complications following removal of maxillary third molar. A 35-year-old female underwent removal of left maxillary third molar at private dental clinic. Following the complete extraction, excessive haemorrhage occurred and maxillary tuberosity fracture was seen and the patient was brought by ambulance to our hospital. The bleeding was controlled by vacuum-formed splint and nasal packing. Computed tomography revealed that lateral maxillary tuberosity and posterior wall of the maxillary sinus was defect and there was a slight intraorbital haematoma via the inferior orbital fissure as well as with extension in the maxillary sinus and adjacent spaces such as buccal, masticator, pterygomaxillary and infratemporal spaces. Because an ophthalmologist noted only slight diplopia in lateral gaze without abnormal signs in other examinations and nasal and oral bleeding were controlled, the surgical treatment was not required. The patient was immediately hospitalised for close observation. Intravenous antibiotics and steroids were administered. Because swelling of the cheek and buccal mucosa was gradually decreasing without further haemorrhage, the patient was discharged 4 days after the extraction. The diplopia was recovered completely 11 days after the extraction.

添付ファイル： Baba_et_al-2017-Oral_Surgery.pdf

DOI： 10.1111/ors.12214

Scopus

researchmap

担当区分：責任著者   記述言語：英語   掲載種別：研究論文（学術雑誌）   出版者・発行元：CHURCHILL LIVINGSTONE  

添付ファイル： Intraoral US.pdf

DOI： 10.1016/j.bjoms.2016.07.032

Web of Science

PubMed

researchmap

担当区分：責任著者   記述言語：英語   掲載種別：研究論文（学術雑誌）   出版者・発行元：LIPPINCOTT WILLIAMS & WILKINS  

添付ファイル： XVL.pdf

DOI： 10.1097/SCS.0000000000003265

Web of Science

PubMed

researchmap

担当区分：筆頭著者,　責任著者   記述言語：英語   掲載種別：研究論文（学術雑誌）   出版者・発行元：SPRINGER  

Bimaxillary orthognathic surgery has been widely performed to achieve optimal functional and esthetic outcomes in patients with dentofacial deformity. Although Le Fort I osteotomy is generally performed before bilateral sagittal split osteotomy (BSSO) in the surgery, in several situations BSSO should be performed first. However, it is very difficult during bimaxillary orthognathic surgery to maintain an accurate centric relation of the condyle and decide the ideal vertical dimension from the skull base to the mandible. We have previously applied a straight locking miniplate (SLM) technique that permits accurate superior maxillary repositioning without the need for intraoperative measurements in bimaxillary orthognathic surgery. Here we describe the application of this technique for accurate bimaxillary repositioning in a mandible-first approach where the SLMs also serve as a condylar positioning device in bimaxillary orthognathic surgery.

添付ファイル： Mandible first.pdf

DOI： 10.1007/s10266-016-0236-7

Web of Science

PubMed

researchmap

記述言語：英語   掲載種別：研究論文（学術雑誌）  

添付ファイル： SCC dorsum.pdf

DOI： 10.1007/s12070-016-0979-z

J-GLOBAL

researchmap

記述言語：英語   掲載種別：研究論文（学術雑誌）  

PURPOSE: This study aimed to evaluate the influence of maxillary impaction orthognathic surgery on nasal respiratory function and the efficacy of bone trimming at the inferior edge of the pyriform aperture. MATERIALS AND METHODS: The participants were 10 patients (3 male and 7 female patients) with mandibular prognathism who underwent bimaxillary orthognathic surgery with maxillary impaction. The surgical procedures performed were Le Fort I osteotomy with bone trimming at the inferior edge of the pyriform aperture and bilateral sagittal split osteotomy. Three-dimensional models of the nasal cavity were reconstructed from preoperative and postoperative computed tomography images. Furthermore, we remodeled the nasal valve region based on the postoperative models by adding a 1-mm and 2-mm stenosis to investigate the effects of bone trimming at the inferior edge of the pyriform aperture on the pressure effort. The 3-dimensional models were simulated with computational fluid dynamics, and the results of the pressure effort and the cross-sectional area (CSA) were compared for the anterior, middle, and posterior parts of the nasal cavity. The Wilcoxon signed rank test and Spearman rank correlation coefficients were used for statistical comparisons (P < .05). RESULTS: In the preoperative and postoperative models, there were considerable correlations between the CSA and the pressure effort in each part of the nasal cavity. The postoperative pressure effort showed a tendency to decrease and the CSA showed a tendency to increase in each part of the nasal cavity. In four 2-mm stenosis models, the pressure effort in the anterior nasal cavity was larger than the preoperative pressure effort and the CSA of the anterior nasal cavity was smaller than the preoperative CSA. CONCLUSIONS: Bone trimming at the inferior edge of the pyriform aperture appears to be useful for avoiding nasal respiratory complications with maxillary impaction.

添付ファイル： CFD.pdf

DOI： 10.1016/j.joms.2016.06.171

PubMed

researchmap

記述言語：英語   掲載種別：研究論文（学術雑誌）   出版者・発行元：CHURCHILL LIVINGSTONE  

Purpose: Endoscope-assisted surgery has widely been adopted as a basic surgical procedure, with various training systems using virtual reality developed for this procedure. In the present study, a basic training system comprising virtual reality for the removal of submandibular glands under endoscope assistance was developed. The efficacy of the training system was verified in novice oral surgeons.
Material and methods: A virtual reality training system was developed using existing haptic devices. Virtual reality models were constructed from computed tomography data to ensure anatomical accuracy. Novice oral surgeons were trained using the developed virtual reality training system.
Results: The developed virtual reality training system included models of the submandibular gland and surrounding connective tissues and blood vessels entering the submandibular gland. Cutting or abrasion of the connective tissue and manipulations, such as elevation of blood vessels, were reproduced by the virtual reality system. A training program using the developed system was devised. Novice oral surgeons were trained in accordance with the devised training program.
Conclusions: Our virtual reality training system for endoscope-assisted removal of the submandibular gland is effective in the training of novice oral surgeons in endoscope-assisted surgery. (C) 2016 The Author(s). Published by Elsevier Ltd on behalf of European Association for Cranio-Maxillo-Facial Surgery.

添付ファイル： VRS.pdf

DOI： 10.1016/j.jcms.2016.08.018

Web of Science

PubMed

researchmap

担当区分：筆頭著者,　責任著者   記述言語：英語   掲載種別：研究論文（学術雑誌）  

添付ファイル： Occlusal splint navigation.pdf

DOI： 10.1007/s12663-015-0860-8

PubMed

researchmap

記述言語：英語   掲載種別：研究論文（学術雑誌）   出版者・発行元：QUINTESSENCE PUBLISHING CO INC  

Purpose: The objective of this study was to compare the rate of implant stability development of as-received and photofunctionalized dental implants in regular and complex cases. Materials and Methods: Forty-nine implants (24 as-received and 25 photofunctionalized) placed in regular or complex cases (simultaneous guided bone regeneration, sinus elevation, or fresh extraction sockets) were studied. Photofunctionalization was performed by ultraviolet (UV) treatment of implants for 15 minutes using a photo device immediately prior to placement, and the generation of superhydrophilicity was conirmed. Implant stability was evaluated by measuring the implant stability quotient (ISQ) at placement (ISQ1) and at stage-two surgery (ISQ2). The rate of implant stability development was evaluated by calculating the osseointegration speed index (OSI), deined as the ISQ increase per month ([ISQ2-ISQ1]/healing time in months). The percentage of innate bone support at placement was evaluated clinically and radiographically. Results: The average OSI was considerably greater for photofunctionalized implants (3.7 +/- 2.9) than for as-received implants (0.0 +/- 1.0). The OSI in complex cases was 4.2 +/- 3.2 for photofunctionalized implants and 0.2 +/- 0.9 for as-received implants. The OSI in cases with simultaneous sinus elevation was 5.5 +/- 3.5 for photofunctionalized implants and 0.2 +/- 1.1 for as-received implants. Photofunctionalized implants showed signiicantly higher ISQ2 values than as-received implants. Photofunctionalized implant ISQ2 values were greater than 60, regardless of primary stability and innate bone support at placement. In multivariate analysis including the effects of photofunctionalization, age and sex of patients, and diameter and length of implants, photofunctionalization showed the strongest inluence on the OSI for both regular and complex cases, while other factors inluenced the OSI only in certain conditions. Conclusion: Photofunctionalization accelerated the rate and enhanced the final level of implant stability development compared with as-received implants, particularly for implants placed into poor-quality bone and other complex cases. Photofunctionalization was a stronger determinant of implant stability than all the other tested implant-and host-related factors.

添付ファイル： Implant Photofunction.pdf

DOI： 10.11607/jomi.4115

Web of Science

PubMed

researchmap

記述言語：英語   掲載種別：研究論文（学術雑誌）  

Both central giant cell granuloma (CGCG) and ossifying fibroma (OF) are relatively common diseases. The synchronous presentation of CGCG and OF is, however, an extremely rare occurrence. We present an unusual case with the synchronous presentation of these two diseases in the maxilla and introduce a surgical strategy based on a combination of the stereolithographic model and navigation system for the treatment of gigantic OF with secondary CGCG.

添付ファイル： Reduction surgery.pdf

DOI： 10.1016/j.anl.2015.08.003

PubMed

researchmap

記述言語：英語   掲載種別：研究論文（学術雑誌）   出版者・発行元：ELSEVIER SCIENCE INC  

Objective. To investigate whether 2-[(18) F] fluoro-2-deoxy-D-glucose (FDG) uptake of primary tumor in oral squamous cell carcinoma (OSCC) could predict prognosis.
Study Design. Sixty-nine patients with OSCC who underwent retrograde superselective intra-arterial chemoradiotherapy were recruited and underwent dual-time-point FDG positron emission tomography twice, before treatment and 4 weeks after treatment. FDG uptake was defined as the standardized uptake value (SUVmax). The retention index (RI) and the percent change in SUV (% change SUV), derived from the dual-time-point scan, were calculated.
Results. On univariate analysis, patients with high pre-SUV, RI, and percent change SUV values had significantly worse overall survival and disease-free survival compared with patients with low values. On multivariate analysis, high pre-RI (&gt;= 20.6%) and high percent change SUV (&gt;= 60.0%) (delayed-image) were associated with significantly worse overall survival. High pre-SUV (&gt;= 9.6) (delayed-image) and high pre-RI (&gt;= 20.6%) were associated with significantly shorter disease-free survival.
Conclusions. Dual-time-point FDG positron emission tomography in OSCC provided prognostic information and predicted patient outcome.

添付ファイル： Prognostic value.pdf

DOI： 10.1016/j.oooo.2015.10.018

Web of Science

PubMed

researchmap

担当区分：責任著者   記述言語：英語   掲載種別：研究論文（学術雑誌）   出版者・発行元：BIOMED CENTRAL LTD  

Background: Patient-specific modelling in clinical studies requires a realistic simulation to be performed within a reasonable computational time. The aim of this study was to develop simple but realistic outflow boundary conditions for patient-specific blood flow simulation which can be used to clarify the distribution of the anticancer agent in intra-arterial chemotherapy for oral cancer.
Methods: In this study, the boundary conditions are expressed as a zero dimension (0D) resistance model of the peripheral vessel network based on the fractal characteristics of branching arteries combined with knowledge of the circulatory system and the energy minimization principle. This resistance model was applied to four patient-specific blood flow simulations at the region where the common carotid artery bifurcates into the internal and external carotid arteries.
Results: Results of these simulations with the proposed boundary conditions were compared with the results of ultrasound measurements for the same patients. The pressure was found to be within the physiological range. The difference in velocity in the superficial temporal artery results in an error of 5.21 +/- 0.78 % between the numerical results and the measurement data.
Conclusions: The proposed outflow boundary conditions, therefore, constitute a simple resistance-based model and can be used for performing accurate simulations with commercial fluid dynamics software.

添付ファイル： Investigation.pdf

DOI： 10.1186/s12938-016-0133-x

Web of Science

PubMed

researchmap

記述言語：英語   掲載種別：研究論文（学術雑誌）   出版者・発行元：ELSEVIER SCI LTD  

Coating biomaterials with a thin hydroxyapatite (HA) was proven effective in enhancing bone compatibility. Segmental bone defects are considered as the most difficult defect to repair in bone regeneration therapy. We developed submicron-thin HA-coated titanium fiber mesh scaffolds to reconstruct immediately loaded segmental mandibular defects and evaluated their bone compatibility in vitro and in vivo. Human osteoblasts attachment, proliferation, and osteocalcin expression in non- and HA-coated scaffolds were evaluated. A 10-mm long segmental bone defect in a rabbit mandibular bone was reconstructed with non- or HA-coated scaffolds, which were removed at 9 and 21 weeks, to evaluate the mechanical strength of the bone-scaffold connection and the bone formation around the scaffold. Expression of osteocalcin was greater in HA-coated scaffolds. In vivo bone formation in HA-coated scaffolds was greater than that in non-coated scaffolds at 21 weeks. Newly formed bone in HA-coated scaffolds mostly restored bone continuity. Scanning electron microscopy identified strong integration of the bone and HA-coated scaffolds. The mechanical strength of the bone-scaffold connection was 3-fold greater in HA-coated scaffolds than that in non-coated scaffolds. These results suggest that a thin HA-coated titanium fiber mesh scaffold is a bone-compatible mandibular reconstruction device in immediately loaded segmental defects. (C) 2015 Elsevier Ltd. All rights reserved.

添付ファイル： Development.pdf

DOI： 10.1016/j.biomaterials.2015.09.034

Web of Science

PubMed

researchmap

担当区分：責任著者   記述言語：英語   掲載種別：研究論文（学術雑誌）  

添付ファイル： Migration implant.pdf

DOI： 10.1007/s10006-015-0484-7

PubMed

researchmap

記述言語：英語   掲載種別：研究論文（学術雑誌）  

researchmap

担当区分：責任著者   記述言語：英語   掲載種別：研究論文（学術雑誌）   出版者・発行元：LIPPINCOTT WILLIAMS & WILKINS  

In maxillary orthognathic surgery, superior repositioning of the maxilla is sometimes difficult, and removal of bony interference, especially around the descending palatine artery ( DPA), is very time-consuming in cases of severe maxillary impaction. Posterior repositioning of the maxilla for removal of bony interference between the posterior maxilla and the pterygoid process is also technically difficult. Because the most common site of hemorrhage in Le Fort I osteotomy is the posterior maxilla, this bone removal is a source of frustration for surgeons in DPA injury. When the DPA is injured during bone removal and ligation is performed, aseptic necrosis of the maxilla may occur. Therefore, a simple and safe method for maxillary superior/posterior repositioning is required to remove osseous interference around the DPA. The authors describe here U-shaped osteotomy around the DPA to prevent posterior osseous interference for superior/posterior repositioning of the maxilla in Le Fort I osteotomy.

添付ファイル： U-shaped osteotomy.pdf

DOI： 10.1097/SCS.0000000000001787

Web of Science

PubMed

researchmap

記述言語：英語   掲載種別：研究論文（学術雑誌）  

添付ファイル： Communications TCN.pdf

researchmap

担当区分：筆頭著者,　責任著者   記述言語：英語   掲載種別：研究論文（学術雑誌）   出版者・発行元：LIPPINCOTT WILLIAMS & WILKINS  

Resorbable plate systems have been used in maxillofacial surgery to obviate the need for plate removal. However, resorbable plates and screws are very costly, and refixation with additional screws may be necessary when reduction or repositioning of the bone segment is inaccurate. Here we report the use of self-tapping metal screws for temporary fixation of a resorbable plating system in maxillofacial surgery to avoid the use of additional screws following inaccurate fixation or the reuse of resorbable screws, which may result in loosening.

添付ファイル： Self tap.pdf

DOI： 10.1097/SCS.0000000000001415

Web of Science

PubMed

researchmap

担当区分：責任著者   記述言語：英語   掲載種別：研究論文（学術雑誌）  

In maxillary orthognathic surgery, superior repositioning of the maxilla is sometimes difficult, and removal of the bony interference, especially around the descending palatine artery, is very time-consuming in cases of severe maxillary impaction. A useful method introduced for superior repositioning of the maxilla is horseshoe-shaped osteotomy combined with Le Fort I osteotomy (horseshoe Le Fort I osteotomy). However, injury to the palatal soft tissue during horseshoe-shaped osteotomy may cause aseptic complications of the maxilla. Therefore, a safe method is required to prevent such injury to reduce the risk for aseptic necrosis. We describe here vital staining of palatal soft tissue in horseshoe Le Fort I osteotomy for safer superior repositioning of the maxilla.

添付ファイル： Vital staining.pdf

DOI： 10.1097/SCS.0000000000001420

PubMed

researchmap

記述言語：英語   掲載種別：研究論文（学術雑誌）   出版者・発行元：W B SAUNDERS CO-ELSEVIER INC  

Purpose: The new technology of photofunctionalization with ultraviolet (UV) light for titanium implants has earned considerable attention. We hypothesized that UV light treatment would enhance bone formation on titanium mesh.
Materials and Methods: We implemented in vitro and in vivo experiments to examine the effectiveness of UV treatment for bone formation on titanium mesh surfaces. Titanium mesh for medical use was prepared as samples, which were autoclaved and stored under dark ambient conditions for 4 weeks. UV treatment was performed for 12 minutes. Carbon contamination, hydrophilicity, and protein adhesion of the titanium mesh surface were examined in an in vitro model. Bone tissue formation around the titanium mesh was observed in a rat femur bone model. The Mann-Whitney U test was used to examine differences between the untreated and UV-treated groups. P values of &lt; .05 were considered significant.
Results: UV-mediated photofunctionalization reduced carbon contamination rates on the untreated titanium mesh surfaces. The hydrophobic surface of the untreated titanium mesh became superhydrophilic after UV-mediated photofunctionalization (P &lt; .01). The amount of protein adsorbed onto the titanium was 1.5 to 3 times greater on the photofunctionalized titanium mesh surfaces than on the untreated titanium mesh surfaces (P &lt; .01). In the animal experiment, the newly formed bone on the UV-treated titanium mesh was approximately 2.5 times greater than that on the untreated mesh (P &lt; .05).
Conclusions: UV-mediated photofunctionalization is effective, as demonstrated by the enhanced bone tissue formation on the titanium mesh. Future studies will focus on bone augmentation using an UV-mediated photofunctionalized titanium implant and mesh. (C) 2014 American Association of Oral and Maxillofacial Surgeons

添付ファイル： Effect of ultraviolet.pdf

DOI： 10.1016/j.joms.2014.05.012

Web of Science

PubMed

researchmap

担当区分：筆頭著者,　責任著者   記述言語：英語   掲載種別：研究論文（学術雑誌）   出版者・発行元：2  

We describe secure surgical method for catheter placement using ultrasonic scalpel via the occipital artery to achieve retrograde superselective intra-arterial chemotherapy for advanced oral cancer, as alternative to approach via the superficial temporal artery.

添付ファイル： OA.pdf

DOI： 10.1007/s12070-012-0501-1

PubMed

researchmap

記述言語：英語   掲載種別：研究論文（学術雑誌）   出版者・発行元：3  

添付ファイル： Hyperthermia resovist.pdf

DOI： 10.1007/s12576-014-0309-8

Web of Science

PubMed

researchmap

記述言語：英語   掲載種別：研究論文（学術雑誌）  

researchmap

記述言語：英語   掲載種別：研究論文（学術雑誌）  

添付ファイル： 1-s2.0-S0167814014001261-main.pdf

researchmap

記述言語：英語   掲載種別：研究論文（学術雑誌）   出版者・発行元：Suppl 1  

添付ファイル： VOD.pdf

DOI： 10.1007/s12070-011-0369-5

PubMed

researchmap

記述言語：英語   掲載種別：研究論文（学術雑誌）  

Cervicofacial subcutaneous emphysema is a rare complication of dental procedures. Although most cases of emphysema occur incidentally with the use of a high-speed air turbine handpiece, there have been some reports over the past decade of cases caused by dental laser treatment. Emphysema as a complication caused by the air cooling spray of a dental laser is not well known, even though dental lasers utilize compressed air just as air turbines and syringes do. In this study, we comprehensively reviewed cases of emphysema attributed to dental laser treatment that appeared in the literature between January 2001 and September 2012, and we included three such cases referred to us. Among 13 cases identified in total, nine had cervicofacial subcutaneous and mediastinal emphysema. Compared with past reviews, the incidence of mediastinal emphysema caused by dental laser treatment was higher than emphysema caused by dental procedure without dental laser use. Eight patients underwent CO2 laser treatment and two underwent Er:YAG laser treatment. Nine patients had emphysema following laser irradiation for soft tissue incision. Dentists and oral surgeons should be cognizant of the potential risk for iatrogenic emphysema caused by the air cooling spray during dental laser treatment and ensure proper usage of lasers.

添付ファイル： Australian Dental Journal - 2013 - Mitsunaga - Cervicofacial subcutaneous emphysema associated with dental laser treatment.pdf

DOI： 10.1111/adj.12119

PubMed

researchmap

記述言語：英語   掲載種別：研究論文（学術雑誌）   出版者・発行元：CHURCHILL LIVINGSTONE  

Treatment of fracture of the naso-orbitoethmoid (NOE) complex is difficult. There are not only aesthetic issues but also functional consequences related to the lacrimal system. Because prophylactic lacrimal intubation for such fractures remains controversial, we have assessed the effectiveness of intraoperative lacrimal intubation to prevent epiphora as a result of such injuries. Thirteen patients diagnosed with craniomaxillofacial fractures including fractures of the NOE complex were included in the study; 10 had unilateral fractures and 3 bilateral. Computed tomography (CT) showed all patients had displaced fragments that had the potential to damage the lacrimal duct. In 7 patients the fractures included the canthal region and in 6 they did not. All patients were treated by open reduction and internal fixation under general anaesthesia, followed by intraoperative lacrimal intubation unilaterally or bilaterally as required. Lacrimal intubation with a silicone tube was successful in all 13 patients (16 sides). The tube was removed 2-9 months (mean 3.8) postoperatively and no subsequent epiphora were seen during follow-up (mean (3-29 months) 11.3 months). Lacrimal intubation for at least 2 months may prevent epiphora caused by injury to the nasolacrimal system after fractures of the NOE complex. (C) 2012 The British Association of Oral and Maxillofacial Surgeons. Published by Elsevier Ltd. All rights reserved.

添付ファイル： Lacrimal intubation.pdf

DOI： 10.1016/j.bjoms.2012.07.005

Web of Science

PubMed

researchmap

担当区分：筆頭著者,　責任著者   記述言語：英語   掲載種別：研究論文（学術雑誌）   出版者・発行元：7  

We report bisphosphonate-related enamel hypoplasia as a rare side effect in a child with idiopathic arterial calcification of infancy. © 2012 The British Association of Oral and Maxillofacial Surgeons.

添付ファイル： BP.pdf

DOI： 10.1016/j.bjoms.2012.05.008

Scopus

PubMed

researchmap

担当区分：筆頭著者,　責任著者   記述言語：英語   掲載種別：研究論文（学術雑誌）   出版者・発行元：CHURCHILL LIVINGSTONE  

添付ファイル： ultrasonic osteotomy.pdf

DOI： 10.1016/j.bjoms.2012.05.012

Web of Science

PubMed

researchmap

担当区分：筆頭著者,　責任著者   記述言語：英語   掲載種別：研究論文（学術雑誌）   出版者・発行元：CHURCHILL LIVINGSTONE  

添付ファイル： safe method.pdf

DOI： 10.1016/j.bjoms.2012.04.076

Web of Science

PubMed

researchmap

担当区分：責任著者   記述言語：英語   掲載種別：研究論文（学術雑誌）   出版者・発行元：LIPPINCOTT WILLIAMS & WILKINS  

Ewing sarcoma (ES) is a primary bone malignant neoplasm and is the second most common primary malignancy of the bone found in childhood and adolescence after osteosarcoma. ES has an annual frequency in the population younger than 20 years of approximately 2.9 per million. ES occurs most frequently in the long bones of the extremities and pelvis and very rarely in the jaw. Recently, it was revealed that chromosomal translocation t(11;22)(q24;q12), which fuses the EWS gene on chromosome 22 and the FLI-1 gene on chromosome 11, occurs inmost cases of ES. We report here a rare case of mandibular ES in a 10-year-old child with chromosomal translocation t(21;22)(q22;q12) in which the EWS gene is fused with the ERG gene on chromosome 21.

添付ファイル： Ewing sarcoma.pdf

DOI： 10.1097/SCS.0b013e31829030ed

Web of Science

PubMed

researchmap

担当区分：責任著者   記述言語：英語   掲載種別：研究論文（学術雑誌）   出版者・発行元：ELSEVIER SCIENCE INC  

Cervicofacial subcutaneous emphysema is a rare complication of dental procedures with an air turbine or syringe, and dentists and oral surgeons sometimes encounter mediastinal emphysema following the presentation of extensive subcutaneous emphysema. Most emphysema occurs incidentally during tooth extraction, restorative treatment, or endodontic treatment, with only a few cases reported of cervicofacial subcutaneous emphysema associated with dental laser treatment. We report a case of cervicofacial subcutaneous and mediastinal emphysema caused by the air cooling spray of dental laser during dental treatment in a 76-year-old woman. After she underwent dental laser treatment, cervicofacial swelling was noted and she was referred to our department. Computed tomography showed both cervicofacial subcutaneous emphysema and mediastinal emphysema. Antibiotics were administered prophylactically and the emphysema disappeared 5 days after the dental laser treatment, without any complications.

添付ファイル： Laser emphysema.pdf

DOI： 10.1016/j.oooo.2011.10.037

Web of Science

PubMed

researchmap

担当区分：筆頭著者,　責任著者   記述言語：英語   掲載種別：研究論文（学術雑誌）   出版者・発行元：KOWSAR PUBL  

Osteoma is a benign, slow-growing osteogenic tumor that sometimes arises from the craniomaxillofacial region, such as the sinus, temporal or jaw bones. Osteoma consists of compact or cancellous bone that may be peripheral, central or extraskeletal type. Peripheral osteoma arises from the periosteum and is commonly a unilateral, pedunculated mushroom-like mass. Peripheral osteoma of the mandible is relatively uncommon, and peripheral osteoma of the mandibular notch is extremely rare, although many cases arise from the mandibular body, angle, condyle, or coronoid process. We report here an unusual peripheral osteoma of the mandibular notch in a 78-year-old nonsyndromic female.

添付ファイル： Osteoma.pdf

DOI： 10.5812/iranjradiol.3734

Web of Science

PubMed

researchmap

担当区分：筆頭著者,　責任著者   記述言語：英語   掲載種別：研究論文（学術雑誌）  

添付ファイル： 1-s2.0-S0266435612003919-main.pdf

researchmap

担当区分：責任著者   記述言語：英語   掲載種別：研究論文（学術雑誌）   出版者・発行元：LIPPINCOTT WILLIAMS & WILKINS  

For accurate superior or posterior repositioning of the maxilla in Le Fort I osteotomy, bone removal around the descending palatine artery (DPA) and maxillary tuberosity is required. Because the most common site of hemorrhage in the Le Fort I osteotomy is the posterior maxilla, this bone removal provides surgeons to surgical frustration of DPA injury. When the DPA is injured during the bone removal and the ligation is performed, aseptic necrosis of the maxilla may occur. Therefore, we report the use of a simple handmade retractor to protect the DPA in Le Fort I osteotomy.

添付ファイル： Handmade.pdf

DOI： 10.1097/SCS.0b013e318285d491

Web of Science

PubMed

researchmap

担当区分：責任著者   記述言語：英語   掲載種別：研究論文（学術雑誌）   出版者・発行元：LIPPINCOTT WILLIAMS & WILKINS  

Actinomyces-associated lesions in the jaw, such as radicular cyst and osteomyelitis, have been reported by many authors. The lesions are caused by infection from peripheral sites and can be seen to contain Actinomyces druses on pathologic examination. To our knowledge, no previous reports have described Actinomyces-associated calcification in the jaw, although the lesions in the jaw often include druses. We report here a rare case of Actinomyces-associated calcifications in a dentigerous cyst of the mandible.

添付ファイル： AA.pdf

DOI： 10.1097/SCS.0b013e31828f2e72

Web of Science

PubMed

researchmap

記述言語：英語   掲載種別：研究論文（学術雑誌）   出版者・発行元：5  

The aim of this experiment was to evaluate the histological effects of zoledronic acid on the periodontal space in rats. 40 male Wistar rats were divided into three zoledronic acid groups and a control group. Zoledronic acid was injected subcutaneously at doses of 10, 50, or 500 μg/kg once a week for 3 weeks. The rats were killed 1 or 9 weeks after the last injection. Histological examination of the periodontal space around the incisor tooth revealed that zoledronic acid did not inhibit tooth development. In the rats killed 1 week after treatment discontinuation, the periodontal space gradually narrowed in response to increasing zoledronic acid doses, and the changes were statistically significant according to ANOVA but not according to ANOVA with post hoc tests. The changes persisted in the high-dose zoledronic acid group despite zoledronic acid discontinuation, with significant differences identified by ANOVA and ANOVA with post hoc tests. Therefore, although zoledronic acid had an insignificant effect on tooth development, it had a significant effect on the periodontal space when high doses were administered. The results of this experiment may provide useful information for future investigations on the role of zoledronic acid in the osteonecrosis of the jaw. © 2012 International Association of Oral and Maxillofacial Surgeons.

添付ファイル： High-dose.pdf

DOI： 10.1016/j.ijom.2012.11.011

Scopus

PubMed

researchmap

記述言語：英語   掲載種別：研究論文（学術雑誌）  

添付ファイル： Oral Surgery - 2012 - Adachi - Osteomyelitis of the jaws associated with osteopetrosis case report of two sisters.pdf

researchmap

記述言語：英語   掲載種別：研究論文（学術雑誌）   出版者・発行元：2  

Endocrine mucin-producing sweat gland carcinoma (EMPSGC) has recently been recognised as a low-grade carcinoma that almost always occurs on the eyelid. This carcinoma is very rare, with only 20 cases (including the present one) having been reported in the literature. EMPSGC is frequently found in association with invasive mucinous carcinoma. While EMPSGC treatments consist of a complete surgical removal, there has been no consensus regarding the surgical margin. Therefore, reports on surgical management of EMPSGC may potentially provide important therapeutic information. Here, we present a case of a 74-year-old man with EMPSGC of the eyelid that repeatedly recurred despite surgical treatments at another institution. After referral to our department, the patient underwent tumour excision. However, the specimen revealed a positive surgical margin and thus, he subsequently underwent a wider excision. There has been no sign of tumour recurrence or metastasis 6 months after his last operation. This article reviews the current literature and discusses the surgical management of EMPSGC. © 2012 The Authors. Australasian Journal of Dermatology © 2012 The Australasian College of Dermatologists.

添付ファイル： Koike_et_al-2013-Australasian_Journal_of_Dermatology.pdf

DOI： 10.1111/j.1440-0960.2011.00857.x

Scopus

PubMed

researchmap

担当区分：筆頭著者,　責任著者   記述言語：英語   掲載種別：研究論文（学術雑誌）   出版者・発行元：CHURCHILL LIVINGSTONE  

添付ファイル： SLNB.pdf

DOI： 10.1016/j.bjoms.2012.03.002

Web of Science

PubMed

researchmap

担当区分：筆頭著者,　責任著者   記述言語：英語   掲載種別：研究論文（学術雑誌）   出版者・発行元：LIPPINCOTT WILLIAMS & WILKINS  

We describe here a case in which sudden hemorrhage from a branch of the maxillary artery during endoscopically assisted transoral reduction of condylar neck fracture was successfully controlled by endoscopic hemostasis with an ultrasonically activated device.

添付ファイル： ENdoscope hemostasis.pdf

DOI： 10.1097/SCS.0b013e3182646b0b

Web of Science

PubMed

researchmap

記述言語：英語   掲載種別：研究論文（学術雑誌）  

添付ファイル： Hematoma.pdf

researchmap

担当区分：責任著者   記述言語：英語   掲載種別：研究論文（学術雑誌）   出版者・発行元：LIPPINCOTT WILLIAMS & WILKINS  

Choristoma is a tumor-like mass consisting of normal cells in an abnormal location. Cartilaginous choristoma, which is composed of ectopic cartilaginous tissue, very rarely presents in the oral cavity and most commonly in the tongue. Here we report an extremely rare case of cartilaginous choristoma of the lower lip.

添付ファイル： Cartilaginous choristoma.compressed (1).pdf

DOI： 10.1097/SCS.0b013e3182801ef8

Web of Science

PubMed

researchmap

担当区分：責任著者   記述言語：英語   掲載種別：研究論文（学術雑誌）  

添付ファイル： 1-s2.0-S0901502712005255-main.pdf

researchmap

担当区分：筆頭著者,　責任著者   記述言語：英語   掲載種別：研究論文（学術雑誌）  

It is recognized that the branches of the external carotid artery (ECA) can show variation, but the presence of a thyrolinguofacial trunk is extremely rare and always originates from the ECA. We report a case of the thyrolinguofacial trunk arising from the carotid bifurcation (CB) on the left side in a 76-year-old man with advanced tongue cancer, as revealed by three-dimensional computed tomography angiography for vascular mapping of the carotid vessels prior to superselective intra-arterial catheterization. The thyrolinguofacial trunk arose 1.6 mm below the CB from the anterior surface of the left CB. The inner diameter of the thyrolinguofacial trunk at origin was 4.4 mm and the angle between the thyrolinguofacial trunk and CB was 128. After a 1.7-mm course, the trunk divided into the superior thyroid artery and a linguofacial trunk, the inner diameters of which were 1.5 and 3.4 mm, respectively, at origin. The angle between the two arteries was 88. After a 9.8-mm course from the bifurcation, the linguofacial trunk divided into the lingual artery and facial artery, the inner diameters of which were 1.8 and 1.9 mm, respectively, at origin. The angle between the two arteries was 61. It is important to recognize such an anatomic variation of the branches of the ECA prior to superselective intra-arterial catheterization or microsurgical reconstruction for head and neck cancer. © 2012 Springer-Verlag.

添付ファイル： TLFT.pdf

DOI： 10.1007/s00276-012-1004-1

Scopus

PubMed

researchmap

担当区分：筆頭著者,　責任著者   記述言語：英語   掲載種別：研究論文（学術雑誌）   出版者・発行元：Churchill Livingstone  

添付ファイル： CAS.pdf

DOI： 10.1016/j.bjoms.2012.03.021

Scopus

PubMed

researchmap

記述言語：英語   掲載種別：研究論文（学術雑誌）   出版者・発行元：LIPPINCOTT WILLIAMS & WILKINS  

With recent improvements in survival duration after cancer treatment, it is becoming increasingly important to study treatment-related morbidity and mortality. Radiation-induced sarcomas in the irradiated field are well-known potential late sequelae of radiotherapy. These tumors are biologically aggressive. In the case described here, a radiation-induced fibrosarcoma appeared at 20 years after initial surgery, radiotherapy, and chemotherapy for an osteosarcoma of the mandibular condyle. Radiation-induced fibrosarcoma is relatively rare in the head and neck region. The details of this case are presented, and diagnostic and management considerations are described.

添付ファイル： Fibrosarcoma.compressed.pdf

DOI： 10.1097/SCS.0b013e31826cf893

Web of Science

PubMed

researchmap

記述言語：英語   掲載種別：研究論文（学術雑誌）   出版者・発行元：CHURCHILL LIVINGSTONE  

This study investigated the bone regeneration properties of titanium fibre mesh as a tissue engineering material. A thin hydroxyapatite (HA) coating on the titanium fibre web was created using the developed molecular precursor method without losing the complex interior structure. HA-coated titanium fibre mesh showed apatite crystal formation in vitro in a human osteoblast culture. Titanium fibre mesh discs with or without a thin HA coating were implanted into rat cranial bone defects, and the animals were killed at 2 and 4 weeks. The in vivo experience revealed that the amount of newly formed bone was significantly higher in the HA-coated titanium fibre mesh than in the non-coated titanium fibre mesh 2 weeks after implantation. These results suggest that thin HA coating enhances osteoblast activity and bone regeneration in the titanium fibre mesh scaffold. Thin HA-coating improved the ability of titanium fibre mesh to act as a bone regeneration scaffold.

添付ファイル： Hydroxyapatite.pdf

DOI： 10.1016/j.ijom.2011.12.035

Web of Science

PubMed

researchmap

記述言語：英語   掲載種別：研究論文（学術雑誌）   出版者・発行元：5  

We report 18F-fluorodeoxyglucose-positive Warthin tumor in a contralateral cervical lymph node mimicking metastasis in tongue cancer staging with positron emission tomography/computed tomography.

添付ファイル： PET.pdf

DOI： 10.1097/SCS.0b013e318266f750

PubMed

researchmap

担当区分：筆頭著者,　責任著者   記述言語：英語   掲載種別：研究論文（学術雑誌）   出版者・発行元：LIPPINCOTT WILLIAMS & WILKINS  

Warthin tumor (WT) accounts for 4% to 13% of all salivary gland tumors. This benign tumor, which commonly arises in the parotid gland, is the second most common tumor of the salivary gland. WT is multicentric in 12% to 20% of patients and is bilateral in 5% to 14%. The mean age at diagnosis is 62 years (range, 12-92 years), and it rarely presents (&lt;6%) before age 40 years. Extraparotid WT, arising from the submandibular gland or cervical lymph node for example, is very infrequent, with corresponding incidences of 0.4% to 6.9% and 8%, respectively. Moreover, WT arising from the minor salivary gland is extremely rare, with a reported incidence of merely 0.1% to 1.2%. We report here WT arising from the minor salivary gland in the buccal mucosa in a 66-year-old woman and review cases of WT of the minor salivary gland reported in the English literature.

添付ファイル： WT.pdf

DOI： 10.1097/SCS.0b013e318254359f

Web of Science

PubMed

researchmap

担当区分：筆頭著者,　責任著者   記述言語：英語   掲載種別：研究論文（学術雑誌）   出版者・発行元：LIPPINCOTT WILLIAMS & WILKINS  

Throat packing is commonly placed in the pharynx before starting oral and maxillofacial surgery under general anesthesia to protect the airway from aspiration of blood and surgical debris. Complications such as airway obstruction may arise if any of the throat packing is retained after extubation, and less commonly, swallowing of the throat packing has been reported. We report endoscopic removal of throat packing gauze swallowed during general anesthesia.

添付ファイル： Throatpack.pdf

DOI： 10.1097/SCS.0b013e3182564bb5

Web of Science

PubMed

researchmap

記述言語：英語   掲載種別：研究論文（学術雑誌）   出版者・発行元：BIOMED CENTRAL LTD  

Background: To improve the accuracy of catheter navigation, it is important to develop a method to predict shifts of carotid artery (CA) bifurcations caused by intraoperative deformation. An important factor affecting the accuracy of electromagnetic maxillofacial catheter navigation systems is CA deformations. We aimed to assess CA deformation in different head and neck positions.Methods: Using two sets of computed tomography angiography (CTA) images of six patients, displacements of the skull (maxillofacial segments), C1-C4 cervical vertebrae, mandible (mandibular segment), and CA along with its branches were analyzed. Segmented rigid bones around CA were considered the main causes of CA deformation. After superimposition of maxillofacial segments, C1-C4 and mandible segments were superimposed separately for displacement measurements. Five bifurcation points (vA-vE) were assessed after extracting the CA centerline. A new standardized coordinate system, regardless of patient-specific scanning positions, was employed. It was created using the principal axes of inertia of the maxillofacial bone segments of patients. Position and orientation parameters were transferred to this coordinate system. CA deformation in different head and neck positions was assessed.Results: Absolute shifts in the center of gravity in the bone models for different segments were C1, 1.02 +/- 0.9; C2, 2.18 +/- 1.81; C3, 4.25 +/- 3.85; C4, 5.90 +/- 5.14; and mandible, 1.75 +/- 2.76 mm. Shifts of CA bifurcations were vA, 5.52 +/- 4.12; vB, 4.02 +/- 3.27; vC, 4.39 +/- 2.42; vD, 4.48 +/- 1.88; and vE, 2.47 +/- 1.32. Displacements, position changes, and orientation changes of C1-C4 segments as well as the displacements of all CA bifurcation points were similar in individual patients.Conclusions: CA deformation was objectively proven as an important factor contributing to errors in maxillofacial navigation. Our study results suggest that small movements of the bones around CA can result in small CA deformations. Although patients' faces were not fixed properly during CT scanning, C1-C4 and vA-vE displacements were similar in individual patients. We proposed a novel method for accumulation of the displacement data, and this study indicated the importance of surrounding bone displacements in predicting CA bifurcation.

添付ファイル： CA deformation.pdf

DOI： 10.1186/1475-925X-11-65

Web of Science

PubMed

researchmap

記述言語：英語   掲載種別：研究論文（学術雑誌）   出版者・発行元：5  

PURPOSE: To evaluate the therapeutic results and histopathological effects of treatment with thermochemoradiation therapy using superselective intra-arterial infusion via the superficial temporal and occipital arteries for N3 cervical lymph node metastases of advanced oral cancer. METHODS AND MATERIALS: Between April 2005 and September 2010, 9 patients with N3 cervical lymph node metastases of oral squamous cell carcinoma underwent thermochemoradiation therapy using superselective intra-arterial infusion with docetaxel (DOC) and cisplatin (CDDP). Treatment consisted of hyperthermia (2-8 sessions), superselective intra-arterial infusions (DOC, total 40-60 mg/m(2); CDDP, total 100-150 mg/m(2)) and daily concurrent radiation therapy (total, 40-60 Gy) for 4-6 weeks. RESULTS: Six of 9 patients underwent neck dissection 5-8 weeks after treatment. In four of these 6 patients, all metastatic lymph nodes, including those at N3, were grade 3 (non-viable tumor cells present) or grade 4 (no tumor cells present) tumors, as classified by the system by Shimosato et al (Shimosato et al Jpn J Clin Oncol 1971;1:19-35). In 2 of these 6 patients, the metastatic lymph nodes were grade 2b (destruction of tumor structures with a small amount of residual viable tumor cells). The other 3 patients did not undergo neck dissection due to distant metastasis after completion of thermochemoradiation therapy (n=2) and refusal (n=1). The patient who refused neck dissection underwent biopsy of the N3 lymph node and primary sites and showed grade 3 cancer. During follow-up, 5 patients were alive without disease, and 4 patients died due to pulmonary metastasis (n=3) and noncancer-related causes (n=1). Five-year survival and locoregional control rates were 51% and 88%, respectively. CONCLUSIONS: Thermochemoradiation therapy using intra-arterial infusion provided good histopathologic effects and locoregional control rates in patients with N3 metastatic lymph nodes. However, patients with N3 metastatic lymph nodes experienced a high rate of distant metastases.

添付ファイル： ThermoCRT.pdf

DOI： 10.1016/j.ijrobp.2012.02.057

PubMed

researchmap

担当区分：責任著者   記述言語：英語   掲載種別：研究論文（学術雑誌）   出版者・発行元：CHURCHILL LIVINGSTONE  

This article describes a simple and accurate technique for maxillary superior repositioning without any intraoperative measurement using reference points that can be the source of error in bimaxillary orthognathic surgery. A bilateral straight locking miniplates (SLMs)/screw system secured to the maxilla and mandible maintains the three-dimensional relationship between the mandible and the skull base precisely like the incisor pin of an articulator in model surgery. The maxilla can then be accurately moved into the planned position identical to that in model surgery by the SLMs technique.

添付ファイル： SLM.pdf

DOI： 10.1016/j.ijom.2012.03.023

Web of Science

PubMed

researchmap

記述言語：英語   掲載種別：研究論文（学術雑誌）   出版者・発行元：4  

添付ファイル： Role of 3D.pdf

DOI： 10.1097/SCS.0b013e31824e2c1d

PubMed

researchmap

担当区分：筆頭著者,　責任著者   記述言語：英語   掲載種別：研究論文（学術雑誌）   出版者・発行元：LIPPINCOTT WILLIAMS & WILKINS  

Removal of a maxillary third molar is a common dental procedure, and oral surgeons rarely experience accidental displacement of a maxillary impacted third molar into the maxillary sinus as a complication of this procedure. In the case in which such displacement occurs, the molar is removed via a transantral (Caldwell-Luc) approach through bone removal or window osteotomy of the anterior wall of the maxillary sinus. However, this approach is highly invasive because 2 surgical fields are required at the socket and the anterior wall of the maxillary sinus. Here, we report as a minimally invasive approach endoscopic removal of a maxillary third molar displaced into the maxillary sinus via the socket.

添付ファイル： Endoscope extration.pdf

DOI： 10.1097/SCS.0b013e318252f1cf

Web of Science

PubMed

researchmap

記述言語：英語   掲載種別：研究論文（学術雑誌）   出版者・発行元：ELSEVIER SCI LTD  

Background: Total orbital floor reconstruction with sheet-shape materials is available for the treatment of extensive and crushed-type blowout fractures. Simple blowout fractures, on the other hand, require only manual reduction without fixation. Although several types of blowout fractures do not require total reconstruction, some fixation is usually necessary.
Methods: Eighteen cases of blowout fracture were treated with transzygomatic Kirschner wire fixation between 2002 and 2009. This technique was applied to simple fracture cases in which periorbital soft tissue re-herniated through the floor defect into the maxillary sinus after manual reduction, despite improvement of the extra-ocular muscle entrapment. The wire was used to directly support the fracture segment in five cases and used together with a maxillary sinus anterior wall bone graft in 13 cases.
Results: Mean follow-up was 12.5 months. Mild diplopia remained as a subjective symptom in one case. None of the cases developed major complications or conspicuous scars on the cheek.
Conclusions: Transzygomatic Kirschner wire fixation for blowout fracture has the advantages of precise and rigid fixation of all parts of the inferior floor, minimal morbidity without requiring an orbital approach and long-term safety without artificial remnants. This technique can be applied for the treatment of simple blowout fractures. (C) 2012 British Association of Plastic, Reconstructive and Aesthetic Surgeons. Published by Elsevier Ltd. All rights reserved.

添付ファイル： K-wire.pdf

DOI： 10.1016/j.bjps.2012.01.025

Web of Science

PubMed

researchmap

担当区分：筆頭著者,　責任著者   記述言語：英語   掲載種別：研究論文（学術雑誌）   出版者・発行元：CHURCHILL LIVINGSTONE  

Variants of the branches of the external carotid artery are common, but it is extremely rare that the occipital artery arises from the internal carotid artery. We investigated the incidence using three-dimensional computed tomographic (CT) angiography. In 265 patients with cancer of the head and neck, we did CT angiography for vascular mapping of the external carotid artery and its branches before reconstruction or superselective intra-arterial chemotherapy. The origin of the occipital artery was detected in 514 of 530 carotid arteries (97%); the incidence of it arising from the internal carotid artery was 0.2%. (C) 2011 The British Association of Oral and Maxillofacial Surgeons. Published by Elsevier Ltd. All rights reserved.

添付ファイル： OA incidence.pdf

DOI： 10.1016/j.bjoms.2011.05.014

Web of Science

PubMed

researchmap

記述言語：英語   掲載種別：研究論文（学術雑誌）   出版者・発行元：2  

添付ファイル： OA ICA.pdf

DOI： 10.5812/iranjradiol.7809

PubMed

researchmap

記述言語：英語   掲載種別：研究論文（学術雑誌）  

添付ファイル： Le_Fort_I_Osteotomy_Under_Navigational_Guidance.70.pdf

researchmap

記述言語：英語   掲載種別：研究論文（学術雑誌）   出版者・発行元：W B SAUNDERS CO LTD  

Objective: The results of reported lymphaticovenous anastomoses include some effects of complex decongestive physiotherapy (CDP). The present study aimed to determine the net effect of lymphaticovenous side-to-end anastomosis (LVSEA) in patients with lower limb lymphoedema treated by preoperative CDP.
Design: Retrospective observational study.
Materials: 37 LVSEAs in 31 patients.
Methods: Volumes of the thigh and leg with oedema were compared between the time of initial examination, and before (application of CDP) and after LVSEA. The patients were divided into two groups based on the number of anastomoses and lymphoscintigraphic findings.
Results: Preoperative CDP resulted in a reduction of 593 ml (both leg and thigh; p &lt; 0.001). After CDP, LVSEA (1-8 anastomoses; average of 5) reduced the volume by 109 ml (52 ml for the thigh (p = 0.01) and 57 ml for the leg (p,= 0.002)). There was no significant difference in volume reduction on lymphoscintigraphy. Volume was significantly reduced (by 55 ml in the, thigh, p = 0.049; 96 ml in the leg, p = 0.006) in the group that underwent 6-8. but not 1-5 LVSEAs.
Conclusions: The net effect of LVSEA on volume reduction was confirmed, but was not particularly large. The need for CDP decreased in some patients postoperatively, and these patients should be considered for evaluation. (C) 2012 European Society for Vascular Surgery. Published by Elsevier Ltd. All rights reserved.

添付ファイル： LVA.pdf

DOI： 10.1016/j.ejvs.2011.12.032

Web of Science

PubMed

researchmap

担当区分：筆頭著者,　責任著者   記述言語：英語   掲載種別：研究論文（学術雑誌）   出版者・発行元：W B SAUNDERS CO-ELSEVIER INC  

添付ファイル： supernumerary.pdf

DOI： 10.1016/j.joms.2011.10.014

Web of Science

PubMed

researchmap

記述言語：英語   掲載種別：研究論文（学術雑誌）   出版者・発行元：SAGE PUBLICATIONS INC  

Background: For patients with senile ptosis, aesthetic blepharoplasty can be combined with ptosis surgery. However, the amount of skin excision necessary in blepharoplasty is not clearly defined by measurements of the upper eyelids.
Objectives: The authors preoperatively evaluate the amount of skin to be excised in blepharoplasty.
Methods: Fifty patients with bilateral senile ptosis were included in this study. The amount of skin to be excised from the upper eyelids was selected based on preoperative measurements of redundant skin, equivalent to the maximum lid height (MLH) while manually stretching the eyelid upwards minus resting lid height (RLH) with the eyes closed passively. Ptosis surgery (such as plication of the aponeurosis) followed blepharoplasty.
Results: Preoperatively, mean MLH was 35 mm on the right and 36 mm on the left. Mean RLH was 25 mm bilaterally. The mean amount (height) of excised skin was 10 mm on the right and 11 mm on the left. At six months postoperatively, mean MLH and RLH were 29 and 23 mm on both sides, respectively. Significant differences between pre- and postoperative MLH and RDH were seen on both sides (P &lt; .001). No complications due to overexcision were observed, but revision was performed for two patients with asymmetry of the lid folds and five patients with recurrence of drooping.
Conclusions: Preoperative measurements of upper eyelid heights (stretched and at rest) appear useful in determining the amount of skin excision required in blepharoplasty for senile ptosis.

添付ファイル： Blepharoplasty.pdf

DOI： 10.1177/1090820X12442681

Web of Science

PubMed

researchmap

担当区分：筆頭著者,　責任著者   記述言語：英語   掲載種別：研究論文（学術雑誌）   出版者・発行元：CHURCHILL LIVINGSTONE  

添付ファイル： 3D model.pdf

DOI： 10.1016/j.bjoms.2011.08.013

Web of Science

PubMed

researchmap

担当区分：筆頭著者,　責任著者   記述言語：英語   掲載種別：研究論文（学術雑誌）   出版者・発行元：SPRINGER FRANCE  

It is well-known that the branches of the external carotid artery (ECA) can show anatomical variation, but it is extremely rare that thyrolingual trunk originates from common carotid artery (CCA). Here we report a case of the thyrolingual trunk arising from the CCA on the right side in a 73-year-old female as revealed by three-dimensional computed tomography angiography for vascular mapping of the carotid vessels before head and neck microsurgical reconstruction. The thyrolingual trunk arose from the anterior surface of the right CCA, with an origin 14.5 mm (difference between the carotid bifurcation and upper border of the origin 12.7 mm) below the carotid bifurcation. The inner diameter of origin of the thyrolingual trunk was 3.5 mm, and the angle between the thyrolingual trunk and the CCA was 130A degrees. After a 10.2-mm course, the thyrolingual trunk divided into the superior thyroid artery (STA) and lingual artery (LA). The inner diameters of the origins of the STA and LA were 1.7 and 1.9 mm, respectively, and the angle between the branches was 94A degrees. It is important to recognize this anatomic variation of the branches of the ECA before the microsurgical reconstruction or super-selective intra-arterial chemotherapy for head and neck cancer.

添付ファイル： TLT.pdf

DOI： 10.1007/s00276-011-0837-3

Web of Science

PubMed

researchmap

記述言語：英語   掲載種別：研究論文（学術雑誌）   出版者・発行元：SPRINGER TOKYO  

The branching patterns of the external carotid artery vary among individuals, and consideration of the proximity of nerves is important during catheter insertion in superselective intra-arterial infusion via the superficial temporal artery. We aimed to evaluate the anatomy of the external carotid artery and its surrounding nerves for safe and accurate administration of superselective intra-arterial chemotherapy via the superficial temporal artery.
We analyzed the external carotid artery and its branches morphometrically in 28 Japanese cadavers (56 sides).
Vascular tortuosity in the preauricular region of the catheter insertion site was observed in 42.9% of the sides; the main trunk of the external carotid artery was excessively tortuous in 25.0% of the sides, primarily in the preparotid region. Faciolingual and superior thyrolingual trunks were observed in 28.6 and 1.8% of the sides, respectively. The superior thyroid, lingual, facial, occipital, and maxillary arteries branched from the external carotid artery above the carotid bifurcation in 41.1% of the sides. The mean distance between the insertion site and maxillary artery was 39.5 mm, indicating the extent of catheter insertion. The auriculotemporal nerve was observed near the superficial temporal artery in the preauricular region in 44.6% of the sides; however, the clearly identifiable nerves in the exposed area were difficult to avoid.
Because of the branching variations observed in individuals and sides, preoperative angiography is extremely important for avoiding complications.

添付ファイル： Anatomy ECA.pdf

DOI： 10.1007/s10147-011-0238-y

Web of Science

researchmap

担当区分：筆頭著者,　責任著者   記述言語：英語   掲載種別：研究論文（学術雑誌）   出版者・発行元：CHURCHILL LIVINGSTONE  

添付ファイル： Methylene blue.pdf

DOI： 10.1016/j.bjoms.2011.02.008

Web of Science

PubMed

researchmap

担当区分：筆頭著者,　責任著者   記述言語：英語   掲載種別：研究論文（学術雑誌）   出版者・発行元：CHURCHILL LIVINGSTONE  

添付ファイル： pressure sore.pdf

DOI： 10.1016/j.bjoms.2011.01.016

Web of Science

PubMed

researchmap

記述言語：英語   掲載種別：研究論文（学術雑誌）   出版者・発行元：WILEY-BLACKWELL  

Background It is tedious and difficult to position a flexible catheter in a target vessel branch within complicated-shaped vessels owing to the lack of real-time visual feedback. Digital subtraction angiography and fluoroscopic guidance are currently used for catheter placement.
Methods The proposed method employs an electromagnetic (EM) tracking system to track a sensor-attached catheter. Vessel centerlines are extracted from the CT angiography image, based on which a navigational information tree is built to facilitate catheter manipulation. A virtual endoscopy technique is adopted to generate virtual intravascular video as visual feedback. Unscented Kalman filtering based image registration is performed to align the EM tracker frame with the anatomical atlas and to envision the target registration error.
Results Preliminary experimental results showed the feasibility and effectiveness of the newmethod, with navigation accuracy of 1.80 +/- 0.85 mm.
Conclusions The proposed method can provide continuous virtual visual feedback to facilitate catheter placement and has the potential for clinical use, with significant reduction in X-ray radiation exposure and doses of contrast agents. Copyright (C) 2011 John Wiley & Sons, Ltd.

添付ファイル： Wang_et_al-2011-The_International_Journal_of_Medical_Robotics_and_Computer_Assisted_Surgery.pdf

DOI： 10.1002/rcs.392

Web of Science

PubMed

researchmap

記述言語：英語   掲載種別：研究論文（学術雑誌）   出版者・発行元：W B SAUNDERS CO-ELSEVIER INC  

添付ファイル： Inclusion cyst.pdf

DOI： 10.1016/j.joms.2010.02.056

Web of Science

PubMed

researchmap

記述言語：英語  

researchmap

担当区分：責任著者   記述言語：英語   掲載種別：研究論文（学術雑誌）   出版者・発行元：SPRINGER TOKYO  

Sebaceous carcinoma is the rarest type of oral malignancies. We report a case of primary sebaceous carcinoma of the tongue. Systemic imaging studies revealed that the patient had a T2N2cM0 (International Union Against Cancer guidelines) primary lingual tumor. Histopathological examination revealed neoplastic sebocytic and basaloid cells, and Sudan III staining and electron microscopy revealed intracytoplasmic lipid droplets. The neoplastic cells stained positive for adipophilin; epithelial membrane antigen; epithelial antigen; and cytokeratins 7, 8, and 15, but negative for cytokeratins 5/6, 18, 19, and 20; the androgen receptor; and carcinoembryonic antigen. Superselective intraarterial chemotherapy was administered via the superficial temporal artery concurrent with daily radiotherapy. Multiple biopsies confirmed a complete response of the primary lesion. The patient then underwent neck dissection followed by pathological examination, which revealed lymph nodes metastases. After postoperative radiotherapy to the neck, distant metastases were identified in the mediastinal lymph nodes and the lung. The patient died 17 months after completing the initial course of chemoradiotherapy. Our case demonstrates that superselective intraarterial chemotherapy combined with concurrent radiotherapy can be effective in treating the primary lesion of patients with a sebaceous carcinoma of the tongue. However, an effective strategy to eradicate metastases has yet to be established.

添付ファイル： Sebaceous ca.pdf

DOI： 10.1007/s00795-010-0521-4

Web of Science

PubMed

researchmap

記述言語：英語  

researchmap

記述言語：英語   掲載種別：研究論文（学術雑誌）  

添付ファイル： Bechet.pdf

DOI： 10.1016/j.ajoms.2009.07.003

Scopus

researchmap

担当区分：筆頭著者,　責任著者   記述言語：英語   掲載種別：研究論文（学術雑誌）   出版者・発行元：ELSEVIER SCI LTD  

添付ファイル： 3DCTA endoscope.pdf

DOI： 10.1016/j.bjps.2009.01.044

Web of Science

PubMed

researchmap

記述言語：英語   掲載種別：研究論文（学術雑誌）   出版者・発行元：CHURCHILL LIVINGSTONE  

This report describes mandibular reconstruction using a 2-step bone transport technique in a cancer patient with type 2 diabetes mellitus (DM) who received radiotherapy before ablative surgery. The bone, measuring 90 mm in length with the mandibular curvature and good alveolar form, was regenerated using a plate-guided method. Three implants were placed 21 months after completion of the first distraction and 14 months after the second distraction. These implants integrated successfully and have remained stable more than 2 years after loading. The results suggest that mandibular reconstruction using bone transport is possible after segmental osteotomy in irradiated cancer patients with DM, although a long treatment period is required.

添付ファイル： Mandibular reconstruction.pdf

DOI： 10.1016/j.ijom.2009.06.027

Web of Science

PubMed

researchmap

担当区分：筆頭著者,　責任著者   記述言語：英語   掲載種別：研究論文（学術雑誌）   出版者・発行元：7  

添付ファイル： alopecia.pdf

DOI： 10.1016/j.bjoms.2009.02.019

PubMed

researchmap

担当区分：筆頭著者,　責任著者   記述言語：英語   掲載種別：研究論文（学術雑誌）   出版者・発行元：5  

添付ファイル： SMG removal.pdf

DOI： 10.1016/j.bjoms.2008.09.001

PubMed

researchmap

担当区分：筆頭著者,　責任著者   記述言語：英語   掲載種別：研究論文（学術雑誌）   出版者・発行元：3  

添付ファイル： Sialendoscopy.pdf

DOI： 10.1016/j.joms.2008.08.043

PubMed

researchmap

記述言語：英語   掲載種別：研究論文（学術雑誌）  

添付ファイル： Sinus floor.pdf

DOI： 10.2485/jhtb.18.83

Scopus

researchmap

記述言語：英語   掲載種別：研究論文（学術雑誌）  

To evaluate the efficacy of tooth extraction wound protection made of atelocollagen sponge (TRE-641), we observed healing in tooth extraction sites filled with TRE-641 and those filled with a control material, oxide cellulose. Subjects were 11 beagle dogs, with a total of 22 extraction sites. Both maxillary lateral incisors were carefully removed, and extraction wounds were filled with TRE-641 on one side and with oxidized cellulose sponge as control on the other side. Wound healing was observed, and the animals were sacrificed at 7, 14, and 28 days after surgery. We compared extent of bone formation, hematoma, inflammation, and graft material remaining between the two groups. At 7 days, newly formed bone extending from the floor and wall of the socket bone were seen in the TRE-641. Hematoma and inflammation were observed in the oxide cellulose. At 14 days, a small amount of TRE-641 remained. In the oxide cellulose group, a small amount of hematoma remained. At 28 days, the extraction socket was filled with newly formed bone in both groups. TRE-641 produced acceptable early phase bone healing at the tooth extraction site with no remnant graft material with sufficient bone formation of the tooth extraction wound. © 2009 The Hard Tissue Biology Network Association.

添付ファイル： TRE.pdf

DOI： 10.2485/jhtb.18.89

Scopus

researchmap

記述言語：英語   掲載種別：研究論文（学術雑誌）   出版者・発行元：2  

β-tricalcium phosphate (β-TCP) was grafted into rat mandibular bone defects to assess its potential as a scaffold material for bone regeneration. For this purpose, β-TCP (TCP), allogenic bone (Allograft), and allogenic bone combined with β-TCP (Combined) were employed as graft materials. To the left side of the graft materials in the bone defects, platelet-rich plasma (PRP) was added. The rats were sacrificed at one, three, and five weeks. Bone formation rate (BFR), remaining β-TCP rate (RTR), β-TCP absorption rate (TAR), whole amount of β-TCP (WTCP), and total rate of BFR and RTR (TBR) were measured. Combined showed equivalent BFR to Allograft at five weeks, and showed higher RTR at one week and higher BFR at five weeks than TCP. Combined with PRP showed higher TAR than that without PRP at three weeks. Therefore, combination with allogenic bone showed reduced β-TCP absorption, hence enhancing the role of β-TCP in bone regeneration. These findings suggested that β-TCP is a better scaffold for bone regeneration if its early absorption is reduced when used in combination with an osteogenic material.

添付ファイル： Combination allo.pdf

DOI： 10.4012/dmj.28.153

Scopus

PubMed

researchmap

担当区分：筆頭著者,　責任著者   記述言語：英語   掲載種別：研究論文（学術雑誌）   出版者・発行元：ELSEVIER SCI LTD  

添付ファイル： EBSSO.pdf

DOI： 10.1016/j.bjps.2008.03.057

Web of Science

PubMed

researchmap

記述言語：英語   掲載種別：研究論文（学術雑誌）   出版者・発行元：6  

OBJECTIVE: To describe vertical distraction osteogenesis of a scapular flap and removable lip support for oral rehabilitation after surgical creation of an ablative defect of the mandible. CASE REPORT: A 70-year-old man who was diagnosed with squamous cell carcinoma of the left lower gingiva underwent segmental mandibulectomy for tumor ablation and reconstruction with a scapular bone flap. To augment bone height of this flap, vertical distraction osteogenesis was performed. After denture fabrication, a removable lip support was placed between the implant-supported denture and the lower lip. RESULTS: The bone height of the scapular bone flap increased by 9 mm. Implants with adequate length could be placed in the distracted bone. The lip support was effective. Two years after masticatory loading, the implants remained stable. CONCLUSION: Vertical distraction osteogenesis of the scapular bone flap was suitable to facilitate postoperative functional and esthetic restoration after tumor resection. A removable lip support was also useful as a supplementary tool for oral rehabilitation.

添付ファイル： Management.pdf

DOI： 10.1016/j.tripleo.2008.05.048

PubMed

researchmap

記述言語：英語   掲載種別：研究論文（学術雑誌）   出版者・発行元：5  

OBJECTIVE: This paper describes a case of secondary mandibular bone reconstruction performed to place dental implants. Osteosynthesis and simultaneous irregular trifocal distraction osteogenesis were documented. PATIENT: The patient was a 51-year-old man with recurrent ameloblastoma of the mandible. Segmental mandibulectomy for tumor ablation and immediate mandibular reconstruction were performed. Because the volume of reconstructed bone was insufficient to place dental implants, trifocal distraction osteogenesis (vertical and horizontal distraction osteogenesis) was performed. Because the mandible had lost its continuity, osteosynthesis was performed simultaneously. RESULTS: Through this procedure, the bone was well augmented. Absorption of the distracted bone was not seen. Adequate-length implants were placed. CONCLUSION: Irregular trifocal distraction osteogenesis synchronized with osteosynthesis shortened the treatment period and produced stable bone augmentation for placement of dental implants. Therefore, this procedure could be indicated for complicated segmental mandibular bone defects.

添付ファイル： Osteosynthesis.pdf

DOI： 10.1016/j.tripleo.2008.03.013

PubMed

researchmap

記述言語：英語   掲載種別：研究論文（学術雑誌）   出版者・発行元：CHURCHILL LIVINGSTONE  

添付ファイル： Branchial cyst.pdf

DOI： 10.1016/j.bjoms.2007.11.002

Web of Science

PubMed

researchmap

記述言語：英語   掲載種別：研究論文（学術雑誌）   出版者・発行元：CHURCHILL LIVINGSTONE  

This paper describes a case of vertical distraction osteogenesis of a free vascularized osteocutaneous scapular flap in the reconstructed mandible before implant therapy. The patient was a 67-year-old woman with squamous cell carcinoma of the right lower gingiva. She underwent segmental mandibulectomy for tumor ablation and reconstruction with an osteocutaneous scapular flap. The distraction protocol, clinical course and implant therapy are presented. Through this procedure, the bone height of the scapular graft increased by 10 rum. Implants with adequate length could be placed in the distracted area. Two years after masticatory loading, the condition of these implants was stable. Vertical distraction osteogenesis of the scapular flap was considered effective when performed before implant therapy, to facilitate postoperative functional and esthetic restoration after tumor resection.

添付ファイル： VD.pdf

DOI： 10.1016/j.ijom.2008.01.002

Web of Science

PubMed

researchmap

記述言語：英語   掲載種別：研究論文（学術雑誌）   出版者・発行元：MOSBY-ELSEVIER  

Salivary duct carcinoma (SDC) is a distinctive and aggressive neoplasm. The most frequent site of origin is the parotid gland, followed by the submandibular gland. SDC originating in the minor salivary glands, particularly in the ectopic glands within the mandible, is extremely rare. We describe a 62-year-old man with SDC in the mandible, who presented with a painless lump in the right submandibular region (later identified as lymph node metastasis) and ipsilateral mental nerve palsy. Histologic examination after ablative surgery revealed SDC originating in the mandible and cervical nodal metastases spreading to levels I-III. The patient remains alive 59 months after presentation as a result of postoperative full-dose irradiation and regular intensive chemotherapy using TXT, 5-FU, and CDDP. However, the patient has local recurrence and distant metastases to the lung and brain. In this report, we also discuss the specific diagnostic criteria and developmental theories of intraosseous salivary gland tumors.

添付ファイル： SDC.pdf

DOI： 10.1016/j.tripleo.2006.01.004

Web of Science

PubMed

researchmap

researchmap

researchmap

researchmap

researchmap

担当区分：筆頭著者,　責任著者   記述言語：日本語   掲載種別：記事・総説・解説・論説等（学術雑誌）  

添付ファイル： ゴールから始める顎骨再建.pdf

researchmap

記述言語：日本語   掲載種別：速報，短報，研究ノート等（学術雑誌）  

添付ファイル： 成人に生じた顎下部リンパ管奇形の1例.pdf

researchmap

担当区分：筆頭著者,　責任著者   記述言語：日本語   掲載種別：記事・総説・解説・論説等（学術雑誌）  

添付ファイル： クリニカル2（岩井俊憲様）　日本歯科医師会雑誌21年11月号.pdf

researchmap

記述言語：日本語  

添付ファイル： 耳下腺貯留嚢胞.pdf

researchmap

記述言語：日本語  

添付ファイル： STF.pdf

researchmap

記述言語：日本語  

添付ファイル： 小児唾石症.pdf

researchmap

記述言語：日本語   掲載種別：記事・総説・解説・論説等（学術雑誌）  

researchmap

記述言語：日本語   出版者・発行元：(一社)日本口腔腫瘍学会  

頭頸部悪性腫瘍において遠隔転移は最も予後に影響する因子である。今回、われわれは肝門部リンパ節転移と腹膜播種性転移に至った。まれな下顎歯肉癌症例を経験した。患者は69歳、男性。右側下顎歯肉扁平上皮癌(T4aN3M0)に対し超選択的動注化学放射線治療を施行した。治療後1ヵ月でのFDG-PET/CT検査で肝門部リンパ節腫大を認めた。その後、腹水を伴う腹膜播種性転移を認めたため入院したが急速に全身状態が悪化し多臓器不全にて死亡した。病理解剖検査の結果、肝門部リンパ節腫大と腹膜播種性転移はいずれも右側下顎歯肉癌の転移であると診断された。(著者抄録)

添付ファイル： 播種性転移.pdf

researchmap

記述言語：日本語   出版者・発行元：(NPO)日本顎変形症学会  

顎変形症治療コンセンサスミーティングの事前に行ったアンケート調査の概要を報告した。参加予定の36施設36人に対してweb入力方式により画面上にてアンケートを実施した。口腔外科医単独で治療計画を立案している施設はなく、19.4%の施設は矯正歯科医が単独で治療計画を立案しており、80.6%の施設は両者が共同で治療を立案していた。38.9%の施設は口腔外科医単独でスプリントを作製しており、44.4%の施設は矯正歯科医が単独で作製していた。両者が共同で作製している施設は16.7%と少なかった。75.0%の施設は半調節性咬合器を用いてスプリントを作製していたが、25.0%の施設は半調節性咬合器を使用していなかった。また、50%の施設では3Dプランニングを行っておらず、69.4%の施設は3Dプリンターを所有していなかった。30.6%の施設は原則全例に3Dモデルを作製しており、52.8%の施設は必要な症例(非対称症例など)のみに作製していた。

添付ファイル： コンセンサスミーティング.pdf

researchmap

記述言語：日本語   掲載種別：記事・総説・解説・論説等（学術雑誌）   出版者・発行元：(公社)日本口腔外科学会  

添付ファイル： CAS.pdf

researchmap

記述言語：日本語   出版者・発行元：(一社)日本口腔診断学会  

症例は50歳代女性で、上顎歯肉の腫脹と出血を認めた。歯周炎の悪化を疑い、アモキシシリンが投与されるも改善せず、下肢の点状出血斑も出現したため、精査目的に当科を紹介受診した。当院血液腫瘍内科に診察を依頼したところ、特発性血小板減少性紫斑病疑いの診断のもと同科に緊急入院となった。入院後、プレドニゾロン(PSL)の経口投与を開始し、出血コントロールのために血小板輸血を10単位行った。入院2日目にも血小板輸血を5単位行ったが、血小板数はさらに低下を認め、追加検査で血小板数の低下以外に尿蛋白陽性、抗核抗体陽性、抗DNA抗体陽性がみられた。全身性エリテマトーデス(SLE)の分類基準を満たしたことからSLEに伴う血小板減少と診断された。血液腫瘍内科からリウマチ科に転科となり、PSLを増量後より血小板数は上昇を認め、入院58日目に退院となった。入院中、口腔内からの持続的な出血は認めず、下肢の点状出血斑も改善傾向であった。

researchmap

記述言語：日本語   出版者・発行元：(公社)日本口腔外科学会  

症例は56歳男性で、右側耳下腺部の腫脹を認め、CTで耳下腺唾石症と診断した。CTでは、右側耳下腺腺体内に3.6×2.5×1.7mm大の唾石を認めた。唾液腺内視鏡で診断的内視鏡検査を行い、耳下腺腺体内の導管の奥に唾石を認めた。唾石の破砕が必要で手術時間が長くなるため、全身麻酔下に内視鏡下唾石摘出術を施行した。手術翌日に退院した。その後の唾液の流出は良好で、術後1年9ヵ月以上経過した現在、耳下腺の腫脹や唾石の再発は認めていない。

添付ファイル： 耳下腺唾石.pdf

researchmap

記述言語：日本語   出版者・発行元：(NPO)日本顎変形症学会  

線維性異形成症(FD)が顎骨に発生し骨の膨隆が著しい場合には、通常の顎矯正手術だけでは良好な顔貌形態が得られないことが多く、骨の削除術が必要となる。しかし、口腔内アプローチによる骨削除術は手術難易度が高く、十分な骨削除が行えないことも多い。今回、下顎FDにより顔面非対称と片側性鋏状咬合を呈した18歳男性例に対して、口内法によるナビゲーションガイド下骨削除術後に片側下顎臼歯部歯槽骨切り術と2分割Le Fort I型骨切り術(臼歯部での歯槽骨切り)行い、良好な結果が得られたので報告した。

添付ファイル： FD Navigation.pdf

researchmap

記述言語：日本語   出版者・発行元：(一社)日本口腔診断学会  

症例は50歳代男性で、右側顎下部の腫脹が食事時に生じたため、近耳鼻咽喉科を受診した。右側顎下腺唾石症と診断され、顎下腺摘出術が必要と説明されたため、唾液腺内視鏡での低侵襲な治療を希望して当科受診となった。唾石は顎下腺腺体上部に存在していたため、内視鏡下での唾石摘出が困難であった場合には、内視鏡をガイドにした口内法で唾石の摘出を行い、それが困難であった場合には顎下腺摘出術が必要になることを患者に説明し、同意を得たうえで全身麻酔での手術を計画した。細い唾液腺内視鏡は腺体内まで挿入可能であり、主導管から2分岐目に唾石を確認できた。唾液腺内視鏡のワーキングチャンネルからバスケット鉗子を挿入し唾石を把持した。唾石が類円形であったこともあり、開口部を切開せずに摘出可能であった。術後2年3ヵ月経過するも顎下腺の腫脹や唾仙痛は認めず、経過良好である。

researchmap

記述言語：日本語   出版者・発行元：(一社)日本口腔診断学会  

症例は70歳代男性で、右側口底部の腫瘤を自覚したが放置していた。その後に腫瘤の増大を認めたため近医歯科を受診した。口底腫瘍と診断され、某総合病院歯科口腔外科を紹介され生検が行われた。扁平上皮癌と診断されたため、加療目的に当科を紹介受診となった。画像所見より正中よりやや右側の口底癌の左側耳下腺リンパ節への転移が疑われたが、腫瘍がT1であり、健側の表在リンパ節であることより、リンパ節内に生じたWarthin腫瘍の可能性も考えられた。そのため、センチネルリンパ節生検を行った。病理組織学的所見では、耳下腺リンパ節は円柱状細胞と立方状細胞の二層性配列を示す上皮が管状、嚢胞状に増生し、間質には濾胞形成を伴うリンパ球浸潤を認め、Warthin腫瘍と診断した。センチネルリンパ節に転移を認めなかったため、経過観察を行い、術後11ヵ月経過するが無病生存中である。

researchmap

記述言語：日本語   出版者・発行元：横浜市立大学医学会  

正中の進行上顎歯肉癌で鼻部に至る場合の拡大手術は顔面皮膚欠損及び口腔機能の障害を伴い、quality of lifeの低下を引き起こす。今回われわれは上唇から鼻部に及ぶ局所進行正中上顎歯肉癌に対し4経路を用いた超選択的動注化学放射線治療を施行した。患者36歳、男性。上顎歯肉癌(T4aN1M0)。患者は手術拒否であったため、4経路を使用した逆行性超選択的動注化学放射線治療(照射total 70Gy、docetaxelをtotal 70mg/m2、cisplatinをtotal 175mg/m2)を施行した。加えて、頸部リンパ節転移に対するハイパーサーミアを週1回、計6回行なった。治療後、腫瘍原発の治療効果判定はCRを得たため原発切除を回避した。治療後58ヵ月経過し現在まで再発・転移なく経過している。(著者抄録)

添付ファイル： 04_Oguri.pdf

researchmap

記述言語：日本語   出版者・発行元：(公社)日本口腔外科学会  

症例は23歳男性で、18歳時に右側鼻腔の狭小化と右上顎の膨隆を指摘され、生検での結果Fibrous dysplasiaと診断された。経過観察されていたが、徐々に上顎が膨隆し顔貌の非対称が強くなったため手術が必要と判断された。手術は、右側上顎の膨隆した骨を顔面の対称性が得られるように削除するために、ナビゲーションシステムを用いた形成術を計画した。上顎右2近心に縦切開を行い、上顎右7まで歯肉縁切開を行った。その後、骨膜下を剥離し、膨隆した上顎骨を明示した。ナビゲーションガイド下にミラーリング像を指標にしながら、膨隆した骨にミラー像の深さまでグループを入れた後に、グループをつなげるようにラウンドバーで骨の削除を行った。術中、患者頭部に固定したリファレンスに助手が触れたことでナビゲーョンの誤差が生じたため、オクルーザルスプリントを両度装着し、再レジストレーションを行った。ナビゲーションの誤差が1mm以内になった後、手術を再開した。その後、プローブで骨削除断端部を触れることで、計画通りの骨削除が行えているかナビゲーションシステムのモニター上で確認しながら、十分な骨削除量が得られるまで手術を行った。術後経過は良好であり、術後9年経過するも左右対称な顔貌が得られている。

添付ファイル： 上顎.pdf

researchmap

記述言語：日本語   出版者・発行元：(一社)日本口腔診断学会  

70歳代女。右側顎下部の腫脹を主訴とした。CTで右側顎下腺の腺体中央部に3.1×2.8×2.6mmの唾石を認め、右側顎下腺腺体内唾石症と診断した。唾石は腺体中央部に存在していたが、大きさが約3mm程度であり、CT値が低いため粉砕が容易にできる可能性が高く、更に顎下腺移行部から唾石まで唾液の貯留が描出されていたことから、内視鏡手術が可能と判断した。受診当日に外来局所麻酔下に内視鏡下唾石摘出術を施行し、手術時間は35分と短く、術後経過は良好であった。術後1年4ヵ月の現在、再発は認めていない。

researchmap

記述言語：日本語   出版者・発行元：(一社)日本口腔診断学会  

15歳男。顔面非対称を主訴とした。7歳時より左耳翼基部の膨隆を自覚し、2年前に生検にて線維性異形成症(FD)と診断されていた。口腔外所見では左鼻翼から鼻根部や頬部にかけて膨隆し、斜鼻を認めた。口腔内所見では左側上顎歯肉唇移行部から口唇粘膜にかけて骨の膨隆を認めた。CTでは左上顎洞を後方に圧排するように境界明瞭な充実性病変を認め、左鼻腔は閉塞していた。3D-CTでは左鼻骨、左上顎骨、左頬骨の膨隆を認めた。FDとしては典型的な画像所見ではなかったため生検を行ったところ、病理組織学的に骨形成線維腫(OF)またはFDの所見であった。画像所見と併せて考えOFと診断し、ナビゲーション手術を計画した。腫瘍を摘出した後、術前に行った健側をミラーリングした画像まで骨の削除を行い、手術を終了した。術直後の3D-CTでは左側上顎の膨隆していた骨が計画通りに削除されていることが確認できた。病理診断はOFであった。術後2年6ヵ月の現在、知覚異常はなく、左右対称の顔貌と左鼻腔の開存が得られている。

researchmap

記述言語：日本語   出版者・発行元：(一社)日本口腔診断学会  

症例は10歳男児で、食事時の右側顎下部の腫脹を認めた。CTにて右側顎下腺唾石症と診断した。右側口底後方粘膜に自壊部を認めたが、排膿は認めなかった。嘔吐反射が強く口底部の触診は困難であった。右側舌下小丘部からの唾液の流出は認めなかった。CTでは右側顎下腺移行部に56×56×42mmの硬組織像を認めた。臨床所見から、急性化膿性顎下腺炎により口底粘膜から排膿ととともに唾石が排出された後に、自壊部から顎下腺移行部に生じた肉芽組織が導管を閉塞させていると考え、閉塞性顎下腺炎と診断した。抗菌薬による消炎を行い、唾液腺内視鏡による閉塞物の摘出術を計画した。全身麻酔下で内視鏡手術を行った。外来経過観察時の唾液の流出は良好となり、以後、顎下腺の腫脹は生じていない。

researchmap

記述言語：日本語   出版者・発行元：(NPO)日本顎変形症学会  

症例は49歳男性で、48歳時に自宅3階の窓から転落し、救急搬送された。全身多発骨折(頸椎・左側下顎頸部・骨体部粉砕骨折、左側肋骨・右側大腿骨・膝蓋骨骨折)に対し救急処置後、口腔外科で受傷1ヵ月後に咬合改善のため、下顎骨観血的整復固定術を受けたが術後より下顎退位を認めた。49歳時にチタンプレート除去術を受け、転落事故後の上顎前歯の突出感、咀嚼障害の改善を希望し、紹介受診した。体格は中等度で、栄養状態は良好であった。顔面は左右対称であるが、両側オトガイ神経領域に瘢痕拘縮を認めた。両側オトガイ神経領域に知覚鈍麻を認め、下顎の前方運動障害と著しい開口障害を認めた。側方運動量は左側3mm、右側1mm、最大開口量は13mmであったが、顎関節強直は認めず、右側下顎頭、左側関節突起の運動を触知できた。全顎的に3〜4mmの歯周ポケットと歯石沈着を認め、下顎右側第一大臼歯、下顎左側犬歯、下顎左側第二小臼歯、下顎左側第一大臼歯は欠如、上顎左側第一小臼歯、上顎左側第三大臼歯は残根を呈していた。前歯部の被蓋関係はオーバージェット+9mm、オーバーバイト+7mmであった。上顎左側第一大臼歯は過萠出し下顎歯槽堤と咬合し、上顎口蓋歯肉に下顎前歯部の圧痕を認めた。CTでは下顎骨体部の粉砕骨折と左側下顎頸部骨折による関節突起の転位脱臼を認めた。治療方針として歯周病治療、上顎左側第三大臼歯抜歯、下顎骨骨延長法と補綴治療による咬合と顔貌の改善を行うこととした。瘢痕拘縮が著しく従来の下顎骨骨延長単独での治療は下顎の前方への延長が困難となる可能性があり、咬合斜面板とII級ゴム併用とした。術後、下顎の後退感は改善し、水平的・垂直的にも適切な前歯・臼歯咬合関係が得られた。術後1年3ヵ月経過したが創部治療良好で、咬合関係も良好である。

DOI： 10.5927/jjjd.27.213

researchmap