-
Expression and Purification of Active Monomeric MMP7.
International journal
Kazuhiro Yamamoto, Moe Isohata, Shouichi Higashi
Methods in molecular biology (Clifton, N.J.)
2747
67
-
73
2024
-
Matrix metalloproteinase-7 induces homotypic tumor cell aggregation via proteolytic cleavage of the membrane-bound Kunitz-type inhibitor HAI-1
Reviewed
Tomohiro Ishikawa, Yayoi Kimura, Hisashi Hirano, Shouichi Higashi
JOURNAL OF BIOLOGICAL CHEMISTRY
292
(
50
)
20769
-
20784
2017.12
-
A novel bacterial transport mechanism of Acinetobacter baumannii via activated human neutrophils through interleukin-8
Reviewed
Go Kamoshida, Shigeru Tansho-Nagakawa, Takane Kikuchi-Ueda, Ryuichi Nakano, Kenji Hikosaka, Satoshi Nishida, Tsuneyuki Ubagai, Shouichi Higashi, Yasuo Ono
JOURNAL OF LEUKOCYTE BIOLOGY
100
(
6
)
1405
-
1412
2016.12
-
Small-molecule auxin inhibitors that target YUCCA are powerful tools for studying auxin function
Reviewed
Yusuke Kakei, Chiaki Yamazaki, Masashi Suzuki, Ayako Nakamura, Akiko Sato, Yosuke Ishida, Rie Kikuchi, Shouichi Higashi, Yumiko Kokudo, Takahiro Ishii, Kazuo Soeno, Yukihisa Shimada
PLANT JOURNAL
84
(
4
)
827
-
837
2015.11
-
Amino-terminal fragments of laminin gamma 2 chain stimulate migration of metastatic breast cancer cells by interacting with CD44
Reviewed
Hiroki Sato, Shouichi Higashi, Kaoru Miyazaki
CLINICAL & EXPERIMENTAL METASTASIS
32
(
5
)
405
-
415
2015.6
-
Inhibition of transforming growth factor-β signaling potentiates tumor cell invasion into collagen matrix induced by fibroblast-derived hepatocyte growth factor.
Reviewed
International journal
Jun Oyanagi, Nako Kojima, Haruki Sato, Shouichi Higashi, Keiji Kikuchi, Katsuya Sakai, Kunio Matsumoto, Kaoru Miyazaki
Experimental cell research
326
(
2
)
267
-
79
2014.8
-
Pericellular proteolysis by matrix metalloproteinase-7 is differentially modulated by cholesterol sulfate, sulfatide, and cardiolipin
Reviewed
Kazuhiro Yamamoto, Kaoru Miyazaki, Shouichi Higashi
FEBS JOURNAL
281
(
15
)
3346
-
3356
2014.8
-
Angiomodulin, a marker of cancer vasculature, is upregulated by vascular endothelial growth factor and increases vascular permeability as a ligand of integrin alpha v beta 3
Reviewed
Eriko Komiya, Hiroki Sato, Naoko Watanabe, Marii Ise, Shouichi Higashi, Yohei Miyagi, Kaoru Miyazaki
CANCER MEDICINE
3
(
3
)
537
-
549
2014.6
-
Modulation of matrix metalloproteinase-9 secretion from tumor-associated macrophage-like cells by proteolytically processed laminin-332 (laminin-5)
Reviewed
Go Kamoshida, Takashi Ogawa, Jun Oyanagi, Hiroki Sato, Eriko Komiya, Shouichi Higashi, Kaoru Miyazaki, Tsutomu Tsuji
CLINICAL & EXPERIMENTAL METASTASIS
31
(
3
)
285
-
291
2014.3
-
Amino-terminal fragments of laminin gamma 2 chain retract vascular endothelial cells and increase vascular permeability
Reviewed
Hiroki Sato, Jun Oyanagi, Eriko Komiya, Takashi Ogawa, Shouichi Higashi, Kaoru Miyazaki
CANCER SCIENCE
105
(
2
)
168
-
175
2014.2
-
Amino-terminal fragments of laminin γ2 chain retract vascular endothelial cells and increase vascular permeability
Reviewed
Hiroki Sato, Jun Oyanagi, Eriko Komiya, Takashi Ogawa, Shouichi Higashi, Kaoru Miyazaki
Cancer Science
105
(
2
)
168
-
175
2014.2
-
Molecular Design of a Highly Selective and Strong Protein Inhibitor against Matrix Metalloproteinase-2 (MMP-2)
Reviewed
Shouichi Higashi, Tomokazu Hirose, Tomoka Takeuchi, Kaoru Miyazaki
JOURNAL OF BIOLOGICAL CHEMISTRY
288
(
13
)
9066
-
9076
2013.3
-
Angiomodulin (AGM/IGFBP-rP1) is overexpressed in tumor vasculature and regulates adhesion of vascular endothelial cells via integrin alpha v beta 3: Possible roles in tumor angiogenesis
Reviewed
Miyazaki Kaoru, Komiya Eriko, Sato Hiroki, Miyagi Yohei, Higashi Shouichi
CANCER RESEARCH
73
2013.2
-
Development of a highly selective inhibitor against matrix metalloproteinase-2 (MMP-2)
63
(
1
)
51
-
61
2013
-
Epithelial-Mesenchymal Transition Stimulates Human Cancer Cells to Extend Microtubule-based Invasive Protrusions and Suppresses Cell Growth in Collagen Gel
Reviewed
Jun Oyanagi, Takashi Ogawa, Hiroki Sato, Shouichi Higashi, Kaoru Miyazaki
PLOS ONE
7
(
12
)
e53209
2012.12
-
Elevated expression of angiomodulin (AGM/IGFBP-rP1) in tumor stroma and its roles in fibroblast activation
Reviewed
Eriko Komiya, Momoko Furuya, Naoko Watanabe, Yohei Miyagi, Shouichi Higashi, Kaoru Miyazaki
CANCER SCIENCE
103
(
4
)
691
-
699
2012.4
-
Structural Basis for Matrix Metalloproteinase-2 (MMP-2)-selective Inhibitory Action of beta-Amyloid Precursor Protein-derived Inhibitor
Reviewed
Hiroshi Hashimoto, Tomoka Takeuchi, Kyoko Komatsu, Kaoru Miyazaki, Mamoru Sato, Shouichi Higashi
JOURNAL OF BIOLOGICAL CHEMISTRY
286
(
38
)
33236
-
33243
2011.9
-
Downregulation of a newly identified laminin, laminin-3B11, in vascular basement membranes of invasive human breast cancers
Reviewed
Taizo Mori, Yoshinobu Kariya, Eriko Komiya, Shouichi Higashi, Yohei Miyagi, Kiyotoshi Sekiguchi, Kaoru Miyazaki
CANCER SCIENCE
102
(
5
)
1095
-
1100
2011.5
-
Laminin-3B11, a Novel Vascular-type Laminin Capable of Inducing Prominent Lamellipodial Protrusions in Microvascular Endothelial Cells
Reviewed
Taizo Mori, Kota Ono, Yoshinobu Kariya, Takashi Ogawa, Shouichi Higashi, Kaoru Miyazaki
JOURNAL OF BIOLOGICAL CHEMISTRY
285
(
45
)
35068
-
35078
2010.11
-
Cholesterol Sulfate Alters Substrate Preference of Matrix Metalloproteinase-7 and Promotes Degradations of Pericellular Laminin-332 and Fibronectin
Reviewed
Kazuhiro Yamamoto, Kaoru Miyazaki, Shouichi Higashi
JOURNAL OF BIOLOGICAL CHEMISTRY
285
(
37
)
28862
-
28873
2010.9
-
Matrilysin (MMP-7) Cleaves C-Type Lectin Domain Family 3 Member A (CLEC3A) on Tumor Cell Surface and Modulates its Cell Adhesion Activity
Reviewed
Jun Tsunezumi, Shouichi Higashi, Kaoru Miyazaki
JOURNAL OF CELLULAR BIOCHEMISTRY
106
(
4
)
693
-
702
2009.3
-
Identification of Amino Acid Residues of Matrix Metalloproteinase-7 Essential for Binding to Cholesterol Sulfate
Reviewed
Shouichi Higashi, Miwa Oeda, Kazuhiro Yamamoto, Kaoru Miyazaki
JOURNAL OF BIOLOGICAL CHEMISTRY
283
(
51
)
35735
-
35744
2008.12
-
Matrilysin (matrix metalloprotease-7) cleaves membrane-bound annexin II and enhances binding of tissue-type plasminogen activator to cancer cell surfaces
Reviewed
Jun Tsunezumi, Kazuhiro Yamamoto, Shouichi Higashi, Kaoru Miyazaki
FEBS JOURNAL
275
(
19
)
4810
-
4823
2008.10
-
Identification of amino acid residues of the matrix metalloproteinase-2 essential for its selective inhibition by beta-amyloid precursor protein-derived inhibitor
Reviewed
Shouichi Higashi, Kaoru Miyazaki
JOURNAL OF BIOLOGICAL CHEMISTRY
283
(
15
)
10068
-
10078
2008.4
-
Matriptase activates stromelysin (MMP-3) and promotes tumor growth and angiogenesis
Reviewed
Xinlian Jin, Motoki Yagi, Nagisa Akiyama, Tomomi Hirosaki, Shouichi Higashi, Chen-Yong Lin, Robert B. Dickson, Hitoshi Kitamura, Kaoru Miyazaki
CANCER SCIENCE
97
(
12
)
1327
-
1334
2006.12
-
Binding of active matrilysin to cell surface cholesterol sulfate is essential for its membrane-associated proteolytic action and induction of homotypic cell adhesion
Reviewed
K Yamamoto, S Higashi, M Kioi, J Tsunezumi, K Honke, K Miyazaki
JOURNAL OF BIOLOGICAL CHEMISTRY
281
(
14
)
9170
-
9180
2006.4
-
Identification of membrane-bound serine proteinase matriptase as processing enzyme of insulin-like growth factor binding protein-related protein-1 (IGFBP-rP1/angiomodulin/mac25)
Reviewed
S Ahmed, XL Jin, M Yagi, C Yasuda, Y Sato, S Higashi, CY Lin, RB Dickson, K Miyazaki
FEBS JOURNAL
273
(
3
)
615
-
627
2006.2
-
Production of soluble matriptase by human cancer cell lines and cell surface activation of its zymogen by trypsin
Reviewed
XL Jin, T Hirosaki, CY Lin, RB Dickson, S Higashi, H Kitamura, K Miyazaki
JOURNAL OF CELLULAR BIOCHEMISTRY
95
(
3
)
632
-
647
2005.6
-
Matrilysin (MMP-7) induces homotypic adhesion of human colon cancer cells and enhances their metastatic potential in nude mouse model
Reviewed
M Kioi, K Yamamoto, S Higashi, N Koshikawa, K Fujita, K Miyazaki
ONCOGENE
22
(
54
)
8662
-
8670
2003.11
-
Proteolytic processing of IGFBP-related protein-1 (TAF/angiomodulin/mac25) modulates its biological activity
Reviewed
S Ahmed, K Yamamoto, Y Sato, T Ogawa, A Herrmann, S Higashi, K Miyazaki
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
310
(
2
)
612
-
618
2003.10
-
Novel processing of beta-amyloid precursor protein catalyzed by membrane type 1 matrix metalloproteinase releases a fragment lacking the inhibitor domain against gelatinase A
Reviewed
S Higashi, K Miyazaki
BIOCHEMISTRY
42
(
21
)
6514
-
6526
2003.6
-
Identification of a region of beta-amyloid precursor protein essential for its gelatinase a inhibitory activity
Reviewed
S Higashi, K Miyazaki
JOURNAL OF BIOLOGICAL CHEMISTRY
278
(
16
)
14020
-
14028
2003.4
-
Factor VIIa modified in the 170 loop shows enhanced catalytic activity but does not change the zymogen-like property
Reviewed
K Soejima, J Mizuguchi, M Yuguchi, T Nakagaki, S Higashi, S Iwanaga
JOURNAL OF BIOLOGICAL CHEMISTRY
276
(
20
)
17229
-
17235
2001.5
-
A novel processing of β-amyloid precursor protein catalyzed by MT1-MMP abrogates its metalloproteinase inhibitor activity
Reviewed
Shouichi Higashi, Kaoru Miyazaki
Keio Journal of Medicine
50
44
-
53
2001
-
Isolation and activity of proteolytic fragment of laminin-5 alpha 3 chain
Reviewed
Y Tsubota, H Mizushima, T Hirosaki, S Higashi, H Yasumitsu, K Miyazaki
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
278
(
3
)
614
-
620
2000.11
-
Expression of trypsin in human cancer cell lines and cancer tissues and its tight binding to soluble form of Alzheimer amyloid precursor protein in culture
Reviewed
S Miyata, N Koshikawa, S Higashi, Y Miyagi, Y Nagashima, S Yanoma, Y Kato, H Yasumitsu, K Miyazaki
JOURNAL OF BIOCHEMISTRY
125
(
6
)
1067
-
1076
1999.6
-
Reactive site-modified tissue inhibitor of metalloproteinases-2 inhibits the cell-mediated activation of progelatinase A
Reviewed
S Higashi, K Miyazaki
JOURNAL OF BIOLOGICAL CHEMISTRY
274
(
15
)
10497
-
10504
1999.4
-
Role of tissue inhibitor of metalloproteinases-2 (TIMP-2) in regulation of pro-gelatinase A activation catalyzed by membrane-type matrix metalloproteinase-1 (MT1-MRP) in human cancer cells
Reviewed
K Shofuda, K Moriyama, A Nishihashi, S Higashi, H Mizushima, H Yasumitsu, K Miki, H Sato, M Seiki, K Miyazaki
JOURNAL OF BIOCHEMISTRY
124
(
2
)
462
-
470
1998.8
-
Molecular interaction between factor VII and tissue factor
Reviewed
Shouichi Higashi, Sadaaki Iwanaga
International Journal of Hematology
67
(
3
)
229
-
241
1998
-
Conformation of factor VIIa stabilized by a labile disulfide bond (Cys-310-Cys-329) in the protease domain is essential for interaction with tissue factor
Reviewed
S Higashi, N Matsumoto, S Iwanaga
JOURNAL OF BIOLOGICAL CHEMISTRY
272
(
41
)
25724
-
25730
1997.10
-
Molecular mechanism of tissue factor-mediated acceleration of factor VIIa activity
Reviewed
S Higashi, N Matsumoto, S Iwanaga
JOURNAL OF BIOLOGICAL CHEMISTRY
271
(
43
)
26569
-
26574
1996.10
-
IDENTIFICATION OF REGIONS OF BOVINE FACTOR-VII ESSENTIAL FOR BINDING TO TISSUE FACTOR
Reviewed
S HIGASHI, H NISHIMURA, K AITA, S IWANAGA
JOURNAL OF BIOLOGICAL CHEMISTRY
269
(
29
)
18891
-
18898
1994.7
-
DEVELOPMENT OF ANTITISSUE FACTOR ANTIBODIES IN PATIENTS AFTER LIVER SURGERY
Reviewed
H TSUDA, S HIGASHI, S IWANAGA, T KUBOTA, T MORITA, K YANAGA
BLOOD
82
(
1
)
96
-
102
1993.7
-
EXPRESSION OF HUMAN SOLUBLE TISSUE FACTOR IN YEAST AND ENZYMATIC-PROPERTIES OF ITS COMPLEX WITH FACTOR-VIIA
Reviewed
Y SHIGEMATSU, T MIYATA, S HIGASHI, T MIKI, JE SADLER, S IWANAGA
JOURNAL OF BIOLOGICAL CHEMISTRY
267
(
30
)
21329
-
21337
1992.10
-
TISSUE FACTOR POTENTIATES THE FACTOR-VIIA-CATALYZED HYDROLYSIS OF AN ESTER SUBSTRATE
Reviewed
S HIGASHI, H NISHIMURA, S FUJII, K TAKADA, S IWANAGA
JOURNAL OF BIOLOGICAL CHEMISTRY
267
(
25
)
17990
-
17996
1992.9
-
Monoclonal antibody (VII-M31) to bovine factor VII: a specific epitope in the gamma-carboxyglutamic acid domain.
Reviewed
Higashi S, Kawabata S, Nishimura H, Funasaki H, Ohyama S, Miyamoto S, Funatsu A, Iwanaga S
The Journal of biochemistry
108
(
4
)
654
-
662
1990.10
