記述言語：英語   掲載種別：研究論文（学術雑誌）  

PURPOSE: To evaluate the clinical outcomes of tube shunt surgery combined with pars plana vitrectomy (PPV) in eyes with neovascular glaucoma (NVG), using either the Ahmed Glaucoma Valve (AGV) or the Baerveldt Glaucoma Implant (BGI). METHODS: This retrospective observational study included 41 eyes of 38 patients with NVG who underwent combined PPV and tube shunt surgery between 2015 and 2020. All tubes were inserted into the vitreous cavity. Intraocular pressure (IOP), number of glaucoma medications (ED score), best-corrected visual acuity (logMAR VA), and complications were analyzed over a follow-up period of up to 5 years. The primary outcome was surgical success, defined as IOP between 6 and 20 mmHg without the need for additional or replacement implants. Kaplan-Meier analysis was performed to evaluate success probability. RESULTS: AGV was implanted in 33 eyes and BGI in 8 eyes. At the final visit, the mean IOP significantly decreased from 32.3 ± 10.1 to 15.5 ± 3.5 mmHg (p < 0.001), and the mean ED score decreased from 5.4 ± 1.5 to 1.5 ± 0.9 (p < 0.001). No significant change was observed in logMAR VA (p = 0.53). The final success rates were 75.0% in the BGI group and 72.7% in the AGV group (p = 0.880). The mean postoperative IOP was significantly lower in the BGI group compared to the AGV group (12.5 ± 4.1 mmHg vs. 16.2 ± 3.0 mmHg, p = 0.025). No severe complications such as endophthalmitis or hypotony were observed. CONCLUSIONS: Tube shunt surgery with PPV and pars plana tube insertion is effective and well tolerated in eyes with NVG. While both AGV and BGI provide comparable success rates, BGI may offer better IOP control.

DOI： 10.1007/s10792-025-03628-w

PubMed

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記述言語：日本語   出版者・発行元：眼科臨床紀要会  

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記述言語：日本語   出版者・発行元：眼科臨床紀要会  

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記述言語：英語   掲載種別：研究論文（学術雑誌）  

PURPOSE: To evaluate the relationship between retinal haemorrhages detected on Ultra-widefield (UWF) red channel images and perfusion status in eyes with acute central retinal vein occlusion (CRVO). METHODS: UWF fundus images were split into green and red channels using ImageJ software. The retinal haemorrhages were calculated quantitatively with both the green and red channel images, resulting in green channel haemorrhages (GCH) and red channel haemorrhages (RCH). The nonperfusion area (NPA) was also calculated from fluorescein angiography in each eye. The relationships between both the GCH and RCH with the NPA were investigated. RESULTS: Thirty-two eyes of 32 patients with acute CRVO (18 men, 14 women) were included. The mean GCH and RCH values were 10.4% ± 8.2% and 1.7% ± 1.7%, respectively. The mean NPA was 39.2% ± 28.8%. Significant correlations were seen between the GCH and NPA (r = 0.38; P = 0.022) and RCH and NPA (r = 0.44; P = 0.010, linear regression analysis). Multivariate analysis suggested that only the RCHs were correlated significantly with the NPA. CONCLUSIONS: Retinal haemorrhages detected by UWF red channel imaging were less compared to green channel imaging and associated closely with retinal NPAs in eyes with acute CRVO. UWF red channel imaging allowed us to identify ischaemia-related haemorrhage.

DOI： 10.1038/s41433-022-02337-3

PubMed

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記述言語：日本語   出版者・発行元：(株)メディカ出版  

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その他リンク： https://search.jamas.or.jp/default/link?pub_year=2025&ichushi_jid=J06107&link_issn=&doc_id=20250327140009&doc_link_id=issn%3D2187-2422%26volume%3D14%26issue%3D2%26spage%3D172&url=http%3A%2F%2Fwww.pieronline.jp%2Fopenurl%3Fissn%3D2187-2422%26volume%3D14%26issue%3D2%26spage%3D172&type=PierOnline&icon=https%3A%2F%2Fjk04.jamas.or.jp%2Ficon%2F00005_2.gif

記述言語：日本語   出版者・発行元：眼科臨床紀要会  

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記述言語：日本語   出版者・発行元：眼科臨床紀要会  

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記述言語：日本語   出版者・発行元：日本神経眼科学会  

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記述言語：日本語   出版者・発行元：日本緑内障学会  

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