Updated on 2025/07/02

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写真a

 
Minori Tateishi
 
Organization
Yokohama City University Hospital Cardiovascular Surgery and Paediatric Cardiology Assistant Professor
Title
Assistant Professor
Other name(s)
Minori Tateishi
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Degree

  • Doctor of Philosophy ( 2023.12   Tokyo Women's Medical University )

Research Interests

  • Pediatric cardiac surgery

  • Adult Congenital Heart Surgery

  • Congenital Heart Disease

  • Cardiovascular Surgery

Research Areas

  • Life Science / Cardiovascular surgery

Education

  • Kumamoto University   School of Medicine   School of Medicine

    1994.4 - 2000.3

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    Country: Japan

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Research History

  • Yokohama City University

    2024.4

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  • Yokohama City University   Assistant Professor

    2023.9 - 2024.3

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    Country:Japan

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  • Seirei Hamamatsu General Hospital   Department of Cardiovascular surgery

    2018.1 - 2023.8

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  • Tokyo Women's Medical University   Department of Cardiovascular surgery

    2013.5 - 2017.12

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    Country:Japan

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  • Tokyo Women's Medical University

    2011.5 - 2013.4

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  • Tokyo Women's Medical University   Department of Cardiovascular surgery

    2009.11 - 2011.3

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  • Kyoto Prefectural University of Medicine   Department of Pediatric Cardiovascular surgery

    2008.4 - 2009.10

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  • Tokyo Women's Medical University   Toyama Prefectural Central Hospital

    2007.7 - 2008.3

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  • Toyama Prefectural Central Hospital   Department of Cardiovascular surgery

    2006.1 - 2007.6

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  • Tokyo Women's Medical University   Department of Cardiovascular surgery

    2005.1 - 2005.12

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  • Seirei Hamamatsu General Hospital   Department of Cardiovascular surgery

    2003.1 - 2004.12

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  • Tokyo Women's Medical University   Department of Cardiovascular surgery

    2002.1 - 2002.12

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  • Kosei hospital   Department of Cardiovascular surgery

    2001.1 - 2001.12

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  • Tokyo Women's Medical University   Department of Cardiovascular surgery

    2000.4 - 2000.12

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Professional Memberships

  • 日本メディカルイラストレーション学会

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  • 日本小児心臓外科医会

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  • 日本女性外科医会

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  • 日本小児集中治療学会

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  • The Japanese Circulation Society

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  • Japan Surgical Society

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  • Japanese Society for Adult Congenial Heart Disease.

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  • Japanese Society of Pediatric Cardiology and Cardiac Surgery

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  • The Japanese Association for Thoracic Surgery

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  • The Japanese Society for Cardiovascular Surgery

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  • Japanese Society for Artificial Organs

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Papers

  • Management for Heterotaxy Syndrome With Functional Single Ventricle and Extracardiac Total Anomalous Pulmonary Venous Connection Reviewed

    Tokyo Women's Medical University Journal   7   2023.12

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    Authorship:Lead author   Publishing type:Doctoral thesis  

    DOI: 10.24488/twmuj.2023003

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  • Endovascular treatment after the fenestrated frozen elephant trunk technique. International journal

    Satoshi Okugi, Masaaki Koide, Yoshifumi Kunii, Minori Tateishi, Risa Shimbori, Hiroki Moriuchi, Masataka Hayashi

    Clinical case reports   10 ( 11 )   e6595   2022.11

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    Recently, several centers have performed total arch replacement using the fenestrated frozen elephant trunk technique for acute Stanford type-A aortic dissection. However, the long-term results and need for additional treatment following this procedure are unclear. We report a case of a 54-year-old man who underwent endovascular therapy for endoleaks after total arch replacement using the fenestrated frozen elephant trunk technique for acute type-A aortic dissection with an isolated left vertebral artery. After the surgery, the endoleak was resolved, and the patient was asymptomatic with no neurological deficits. This strategy might be effective in similar cases.

    DOI: 10.1002/ccr3.6595

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  • Tetralogy of Fallot with severe ascending aortic enlargement in early childhood.

    Satoshi Okugi, Masaaki Koide, Yoshifumi Kunii, Minori Tateishi, Risa Shimbori, Hiroki Moriuchi, Yoshiro Otsuki

    General thoracic and cardiovascular surgery   70 ( 5 )   491 - 494   2022.5

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    The Rastelli procedure is indicated for repair of tetralogy of Fallot (TOF) with pulmonary atresia. However, currently, there are no criteria available for concomitant surgical intervention for an enlarged ascending aorta in infancy. We report a rare case of TOF with pulmonary atresia complicated by severe enlargement of the ascending aorta in a girl aged 2 years and 5 months. We performed the Rastelli procedure with ascending aorta replacement. Pathological findings of the ascending aorta included fragmentation of elastic fibers and loss of smooth muscle cells. Postoperatively, the patient remained healthy and asymptomatic. This case indicates that ascending aortic enlargement in conotruncal anomalies may be associated with pathological lesion even in early childhood. Replacement of the diseased aorta could be considered as a concomitant procedure with definitive repair for conotruncal anomalies presenting with severe ascending aortic enlargement.

    DOI: 10.1007/s11748-021-01766-3

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  • A case of double-chambered right ventricle due to cap-like fibrous tissue and aberrant chordal insertion of tricuspid valve in adult. International journal

    Risa Shimbori, Masaaki Koide, Minori Tateishi, Yoshifumi Kunii, Satoshi Okugi

    Journal of cardiac surgery   37 ( 4 )   1042 - 1043   2022.4

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    BACKGROUND: A double-chambered right ventricle is a rare congenital heart disease where an anomalous structure divides the right ventricle into two cavities. CASE: A 78-year-old man with dyspnea was referred to our institution for a double-chambered right ventricle (DCRV) and ventricular septal defect (VSD). Echocardiography showed normal left ventricular function, right ventricular hypertrophy, and mild tricuspid regurgitation. On parasternal short-axis views, color-flow Doppler studies showed a mosaic pattern through the stenotic right ventricular outflow tract (RVOT). Cardiac catheterization showed a 122 mmHg pressure gradient between the high-pressure chamber and the low-pressure chamber of the RVOT. Computed tomography showed a cap-like structure consisting of fibrous tissue, with moderate stenosis, which divided the right ventricle into two cavities. The aberrant tendinous chords supporting the anterior leaflet of the tricuspid valve were found inserted into the anterior wall of the RV (Figure 1). Resection of the cap-like fibrous tissue and abnormal muscle (Figure 2), detachment of aberrant tendinous chords of the tricuspid valve, closure of VSD by direct suture, and tricuspid valve plasty (TVP) were performed. TVP was achieved using an artificial chordae replacement with expanded polytetrafluoroethylene (CV-5) suture and a 32-mm Physio Tricuspid annuloplasty ring (Edwards Lifeline). Postoperative echocardiography revealed no RVOT pressure gradient and a normal right ventricular pressure of 21 mmHg. DISCUSSION: In conclusion, we report a rare case of DCRV secondary to a cap-like structure fibrous tissue with anomalous chordal insertion of a tricuspid valve leaflet.

    DOI: 10.1111/jocs.16249

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  • Traumatic rupture of an excluded abdominal aortic aneurysm 2 years after endovascular aneurysm repair. International journal

    Satoshi Okugi, Yoshifumi Kunii, Masaaki Koide, Minori Tateishi, Risa Shimbori, Hiroki Moriuchi

    Journal of vascular surgery cases and innovative techniques   7 ( 3 )   415 - 416   2021.9

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    DOI: 10.1016/j.jvscit.2021.04.024

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  • Repair of a unique sinus of Valsalva defect in an infant. International journal

    Satoshi Okugi, Masaaki Koide, Yoshifumi Kunii, Minori Tateishi, Risa Shimbori, Hiroki Moriuchi

    Journal of cardiac surgery   36 ( 6 )   2133 - 2135   2021.6

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    Sinus of Valsalva aneurysm is a rare disease characterized by the partial elevation of the aortic root. Few reports are available on the surgical treatment for infants. We report the repair of an extremely rare case of a sinus of Valsalva defect with a ventricular septal defect and right ventricular outflow tract stenosis in an infant. It was not a sinus of Valsalva aneurysm, but it exhibited abnormal partial bulging of the aortic root and forming an aneurysm-like cavity within the right ventricular myocardium. We performed direct closure of the sinus of Valsalva aneurysm-like cavities and intracardiac repair in two stages. Three years after total repair, the patient remained healthy and asymptomatic.

    DOI: 10.1111/jocs.15451

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  • Computed tomography perfusion in patients of stroke with left ventricular assist device.

    Kazufumi Suzuki, Tomohiro Nishinaka, Minori Tateishi, Yuki Ichihara, Kayoko Abe, Hiroshi Niinami, Shuji Sakai

    Heart and vessels   36 ( 1 )   121 - 126   2021.1

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    Left ventricular assist devices (LVAD) are widely applied for patients with severe heart failure as a bridge to heart transplantation as well as destination therapy. Patients with implanted LVAD have an increased risk of cerebral thrombosis and computed tomographic perfusion (CTP) has the potential to be performed for early diagnosis and treatment of acute ischemic stroke (AIS), including interventional thrombectomy. Here, we report our series of CTP examination in patients having suspected AIS after LVAD implantation. We retrospectively investigated 33 contrast-enhanced CTPs from January 2017 to December 2018 which were performed in 12 cases of patients because of possible neurological findings leading to suspected AIS during LVAD circulatory support who did not have definite ischemic findings nor intracerebral hemorrhage on non-contrast computed tomography. AIS with perfusion disturbance area was diagnosed in 11 (33.3%) out of a total of 33 CTPs in 4 (33.3%) out of 12 patients. Endovascular thrombectomy (EVT) was successfully performed in this research study four times for three patients. CTP was able to detect and determine the indication for EVT without serious complications. CTP could potentially be the first-choice assessment for early diagnosis of AIS with recoverable ischemic penumbra in patients with LVAD implantation.

    DOI: 10.1007/s00380-020-01674-1

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  • Late Period Rastelli Take-Down and Arterial Switch Operation After Rastelli Operation. International journal

    Satoshi Okugi, Masaaki Koide, Yoshifumi Kunii, Minori Tateishi, Yuchen Cao, Risa Shimbori

    The Annals of thoracic surgery   110 ( 6 )   e525-e527   2020.12

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    The Rastelli operation is a useful technique for treating the transposition of the great arteries. However, conduit stenosis of the right ventricular outflow tract is a late complication of the procedure. We report the case of a 35-year-old man for whom an arterial switch operation was performed to treat conduit stenosis and improve ventricular arterial alignment 28 years after he underwent a Rastelli operation to treat transposition of the great arteries with a ventricular septal defect. In the 8 years that followed the operation, he was asymptomatic and was treated with warfarin.

    DOI: 10.1016/j.athoracsur.2020.04.073

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  • Leaflet and coronary stent thrombosis after transcatheter aortic valve implantation treated by aortic valve replacement. International journal

    Satoshi Okugi, Masaaki Koide, Yoshifumi Kunii, Minori Tateishi, Yuchen Cao

    European heart journal. Cardiovascular Imaging   21 ( 3 )   347 - 347   2020.3

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    DOI: 10.1093/ehjci/jez264

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  • Mitral Valve Repair in a Jehovah's Witnesses Patient with Post Myocardial Infarction Papillary Muscle Rupture;Report of a Case

    Taku Masuda, Masaaki Koide, Yuchen Cao, Yosuke Sakurai, Satoshi Okugi, Minori Tateishi, Yoshihumi Kunii

    Kyobu geka. The Japanese journal of thoracic surgery   72 ( 12 )   1005 - 1008   2019.11

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    Language:Japanese   Publishing type:Research paper (scientific journal)   Publisher:NLM (Medline)  

    A 70-years old man was referred to our department for acute heart failure due to post myocardial infarction papillary muscle rupture. We planned emergent surgery, but he refused blood transfusion because of religious reason( Jehovah's Witness). Therefore, we chose medical therapy using intra-aortic balloon pumping and catecholamine. He was also treated with subcutaneous erythropoietin and intravenous iron supplement to increase preoperative hemoglobin. One month later, we decided to undergo mitral valve repair because he was stabilized with medical treatment. The patient underwent mitral valve repair with artificial chordae through median sternotomy. The mitral valve A3 prolapse was caused by posterior papillary muscle rupture. No blood transfusion was given and postoperative course was uneventful. We experienced successful mitral repair for post infarction papillary muscle rupture in a Jehova's Witnessess patient.

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  • Surgical treatment of cardiac fibroma in a child with left ventricular noncompaction. International journal

    Yosuke Sakurai, Yoshifumi Kunii, Minori Tateishi, Satoshi Okugi, Yuchen Cao, Masaaki Koide

    Journal of cardiac surgery   34 ( 10 )   1120 - 1122   2019.10

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    Surgical treatment of cardiac fibroma is rare in patients with left ventricular noncompaction (LVNC). Although several case reports regarding cardiac fibroma have been published, resection in a patient with LVNC has not been described. Here, we describe the surgical treatment of left ventricular fibroma in a child with LVNC. We resected a cardiac fibroma in a 10-year-old boy with LVNC to control ventricular arrhythmia. Partial resection with careful tumor dissection was performed to avoid endocardial damage and entering the ventricular cavity. The postoperative course was uneventful, and the patient remains asymptomatic without heart failure or arrhythmia. Surgical excision of cardiac fibroma can be performed safely with excellent results, even in a child with LVNC.

    DOI: 10.1111/jocs.14183

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  • Aortopulmonary Fistula Caused by Rupture of an Aortic Arch Aneurysm Successfully Treated by Surgery;Report of a Case

    Hiroki Yamazaki, Masaaki Koide, Yoshifumi Kunii, Minori Tateishi, Satoshi Okugi, Yousuke Sakurai, Yuchen Cao

    Kyobu geka. The Japanese journal of thoracic surgery   72 ( 8 )   626 - 629   2019.8

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    An 81-year-old woman who presented with chest and back pain was diagnosed as aortopulmonary fistula caused by rupture of an aortic arch aneurysm and was transferred to our hospital for surgical treatment. Additionally, she was diagnosed with aortic dissection( Stanford type B). Total arch replacement with open stent-grafting and direct closure of aortopulmonary fistula were performed because of her exacerbation of congestive heart failure. Manual compression of fistula during cardiopulmonary bypass was effective to control massive shunt. The patient recovered uneventfully and was transferred to other hospital for rehabilitation on postoperative day 24.

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  • Severely Kinked Pseudocoarctation of the Aorta With Unicuspid Aortic Valve. International journal

    Yosuke Sakurai, Masaaki Koide, Yoshifumi Kunii, Minori Tateishi, Satoshi Okugi, Yuchen Cao

    The Annals of thoracic surgery   107 ( 6 )   e421   2019.6

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    DOI: 10.1016/j.athoracsur.2019.01.027

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  • Infective Endocarditis in Right Ventricle( RV)-Pulmonary Artery( PA) Conduit Late after the Ross Procedure;Report of a Case

    Yuchen Cao, Masaaki Koide, Yoshifumi Kunii, Minori Tateishi, Satoshi Okugi, Yosuke Sakurai, Yasumi Nakashima, Sachie Kaneko, Nao Inoue

    Kyobu geka. The Japanese journal of thoracic surgery   72 ( 2 )   156 - 159   2019.2

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    Ross procedure has been found to have a lower incidence of infective endocarditis compared to other aortic replacement procedure using prosthetic valves. We report a case of 25-year-old man who underwent Ross procedure for congenital aortic stenosis and regurgitation when he was 7 years old. He presented with fever and was highly suspected of infective endocarditis. All sets of blood cultures were positive for Heamophilus parainfluenzae. Autologous pericardial pulmonary valve was severely stenotic and computed tomography (CT) scan and radio isotope (RI) scan revealed infection at the stenotic valve. We performed right ventricle (RV)-pulmonary artery (PA) conduit replacement and he was discharged after completion of intravenous antibiotic treatment. We experienced a rare case of infective endocarditis in a patient late after Ross procedure. Prophylaxis against infective endocarditis is mandatory even in patients with infection resistant Ross procedure.

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  • Long-term follow-up of Fontan completion in adults and adolescents. International journal

    Tai Fuchigami, Mitsugi Nagashima, Takeshi Hiramatsu, Goki Matsumura, Minori Tateishi, Noriyasu Masuda, Kenji Yamazaki

    Journal of cardiac surgery   32 ( 7 )   436 - 442   2017.7

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    BACKGROUND: The Fontan procedure is rarely performed in adults and adolescents in the present era. We review our results with the Fontan procedure in adolescents and young adults. METHODS: Between 1974 and 2010, 79 consecutive patients underwent the Fontan procedure at an age ≥ 15 years (mean age at Fontan operation, 20.3 years ± 4.5 years). Forty-five patients underwent atriopulmonary connection, 11 underwent the Bjork procedure, and 23 underwent total cavopulmonary connection. RESULTS: Ten hospital deaths (HDs) and/or early Fontan takedowns (TDs) occurred. The median follow-up period was 18.2 years (range, 0.6-37.6 years). The estimated freedom from death or TD rates was 79.7% at 5 years, 77.0% at 10 years, 73.9% at 15 years, and 63.9% at 20 years. Age was not a predictor of HD and/or TD. Freedom from death or TD after 1998 was 69.1% at 5 years, 69.1% at 10 years, and 69.1% at 15 years, and before 1997 was 82.3% at 5 years, 79.0% at 10 years, 75.5% at 15 years, and 65.1% at 20 years; there were no significant differences between the two groups. In 19 late-death patients, nine (47.4%) experienced sudden death. Among these patients, five had known arrhythmias before sudden death. CONCLUSIONS: In patients who were ≥15 years old, the surgical results of the Fontan operation were acceptable. Approximately half of the late deaths were sudden deaths, mainly occurring 10-20 years postoperatively.

    DOI: 10.1111/jocs.13157

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  • Long-Term Follow-Up of the Conal Flap Method for Tricuspid Malinsertion in Transposition of the Great Arteries With Ventricular Septal Defect and Pulmonary Stenosis. International journal

    Tai Fuchigami, Mitsugi Nagashima, Takeshi Hiramatsu, Goki Matsumura, Minori Tateishi, Kenji Yamazaki

    The Annals of thoracic surgery   102 ( 1 )   186 - 91   2016.7

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    BACKGROUND: Rastelli and réparation à l'étage ventriculaire (REV) procedures have been applied for biventricular repair of transposition of great arteries with ventricular septal defects and pulmonary stenosis (TGA III). In some patients with TGA III, whose tricuspid valve (TV) chordae tendineae are attached to the infundibular septum, abnormal TV chorda insertion may cause intracardiac rerouting obstruction. For such cases, we performed a conal flap" (CF) procedure involving mobilization of the infundibular septum including TV chordae as a pedicled flap. This study evaluated the long-term outcomes of this CF method. METHODS: Between October 1985 and December 1999, 17 consecutive patients with TGA III underwent a Rastelli-type or an REV-type procedure using CF. Median age at operation was 4.8 years (range, 1.5 to 14.0 years). RESULTS: The mean follow-up period was 17.8 ± 7.2 years. One hospital death and one late death occurred. The freedom from death rates were 94.1%, 94.1%, and 85.6% at 5, 10, and 15 years, respectively. The freedom from death or reoperation rates were 94.1%, 55.8%, and 46.5% at 5, 10, and 15 years, respectively. No reoperations were performed for the left ventricular outflow tract (LVOT) or TV. The average LVOT maximum flow velocity was 1.26 ± 0.50 m/s. TV regurgitation was greater than mild in 3 patients (20%) and trivial to mild in 12 patients (80%). Thirteen patients were in New York Heart Association (NYHA) functional class I, and 2 patients were in NYHA functional class II. CONCLUSIONS: The long-term outcomes, including the daily life activities, LVOT pressure gradients, and TV regurgitation grades, were excellent in patients who underwent Rastelli-type and REV-type procedures using CF for TGA III.

    DOI: 10.1016/j.athoracsur.2016.01.055

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  • 女性外科医における「短時間勤務制度」の有用性と問題点

    立石 実, 冨澤 康子, 長嶋 光樹, 平松 健司, 山崎 健二

    日本外科学会雑誌   116 ( 3 )   185 - 188   2015.5

  • Cardiac tamponade due to perforation by an Amplatzer atrial septal occluder in a patient with Marfan syndrome.

    Minori Tateishi, Takeshi Hiramatsu, Yasuko Tomizawa, Goki Matsumura, Takeshi Konuma, Kenji Yamazaki, Hideshi Yamamura, Toshio Nakanishi

    Journal of artificial organs : the official journal of the Japanese Society for Artificial Organs   14 ( 3 )   261 - 3   2011.9

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    Device closure of atrial septum defect was performed using an Amplatzer septal occluder in a 48-year-old patient with Marfan syndrome. Acute tamponade due to perforation was observed 2 months after catheter intervention. Careful consideration of the indication for device closure for atrium septal defect is necessary in patients with Marfan syndrome.

    DOI: 10.1007/s10047-011-0576-6

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  • Intravascular foreign bodies: danger of unretrieved fragmented medical devices.

    Minori Tateishi, Yasuko Tomizawa

    Journal of artificial organs : the official journal of the Japanese Society for Artificial Organs   12 ( 2 )   80 - 9   2009

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    A warning on the danger of unretrieved device fragments and recommendations to mitigate the danger were issued by the Food and Drug Administration in January 2008. The causes of intravascular foreign bodies are classified into three main categories: improper manipulation and usage, device defects, and others, such as patient and anatomical factors. Device failure after long-term use is rarely predicted at the time of approval, since device abnormality is rarely experienced in animal studies and clinical trials conducted during development of the device. Stent fracture due to metal fatigue is one example. Complex complications could occur from simultaneous use of two or more devices with diverse characteristics. The success rate of percutaneous retrieval of intravascular foreign bodies has improved with the advances in commercially available devices. However, the procedure is not always successful and sometimes surgical removal becomes necessary. Appropriate device selection and acquisition of experience in using the device are important. When an intravascular foreign body cannot be retrieved, the risk of complication could be high. Magnetic resonance imaging examination sometimes causes adverse events, including burns due to the heat generated by metal movement. Such information should be correctly recorded. Furthermore, it is necessary to provide patients with adequate information about the characteristics of implanted devices and unretrieved fragments. We reviewed the literature on unretrieved medical device fragments and include articles that describe the Japanese experience.

    DOI: 10.1007/s10047-009-0447-6

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  • Tetralogy of Fallot with atypical coarctation of the aorta and carotid arterial stenosis due to fibromuscular dysplasia. International journal

    Minori Tateishi, Masaaki Koide, Ayumi Mizukami

    Cardiology in the young   17 ( 6 )   689 - 90   2007.12

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  • 【無脾症候群の治療戦略】無脾症に合併した総肺静脈還流異常の全身麻酔呼吸停止下MD-CTによる術前評価

    立石 実, 小出 昌秋, 国井 佳文, 渡邊 一正, 水上 愛弓, 武田 紹, 竹内 啓人, 増井 孝之

    日本小児循環器学会雑誌   23 ( 2 )   102 - 108   2007.3

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    特異な形態を有する総肺静脈還流異常を合併した無脾症の3例に対し、全身麻酔呼吸停止下で16列multidetector-row CT(MD-CT)による術前評価を行った。MD-CT所見では、3症例は右室性単心室、単心房、共通房室弁、及び総肺静脈還流異常を伴っていた。共通肺静脈腔と心房との位置関係の確認、複数の肺静脈の同定にMD-CT所見を用い、両方向性グレン手術と同時に肺静脈還流異常修復術を行った。いずれも両方向性グレン手術後の経過は良好で、Fontan手術待機中である。MD-CTにより血管造影では困難な肺静脈の詳細な形態の情報が得られ、術式選択に有用であった。

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    Other Link: https://search.jamas.or.jp/default/link?pub_year=2007&ichushi_jid=J02003&link_issn=&doc_id=20070403140003&doc_link_id=%2Fee7shoni%2F2007%2F002302%2F005%2F0102-0108%26dl%3D0&url=https%3A%2F%2Fwww.medicalonline.jp%2Fjamas.php%3FGoodsID%3D%2Fee7shoni%2F2007%2F002302%2F005%2F0102-0108%26dl%3D0&type=MedicalOnline&icon=https%3A%2F%2Fjk04.jamas.or.jp%2Ficon%2F00004_2.gif

  • 末梢性肺動脈高度狭窄を有する純型肺動脈閉鎖、大動脈弁狭窄症に対して術中肺動脈ステント留置術、fenestrated Fontan手術を行った1例

    立石 実, 小出 昌秋, 打田 俊司, 渡邊 一正

    日本心臓血管外科学会雑誌   35 ( 5 )   281 - 285   2006.9

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    症例は12歳、女児。純型肺動脈閉鎖症と診断され、2歳時に大動脈弁狭窄(弁性)に対してバルーン拡大術、5歳時に両方向性Glenn手術と大動脈弁形成術を行ったが、7歳時の心臓カテーテル検査の結果、当時のFontan手術適応外と判断された。その後、チアノーゼの悪化と運動耐容能の低下を認め、治療方針を再検討し、まず、体肺側副血行に対してコイル栓塞術を行い、ひきつづき根治手術を行った。可能なかぎり低侵襲で行うため、末梢性肺動脈狭窄に対して術中ステント留置を併用し、人工血管を用いた心外導管による心拍動下fenestrated Fontan手術を行った。術後経過は良好で、運動耐容能も飛躍的に改善した。Fontanの手術成績は安定し、その適応は拡大しつつあるが、依然Fontanに到達せず、適応外とされる症例が少なからず存在する。今回、末梢性肺動脈狭窄を有し、PA index 89mm2/m2のハイリスク症例に対し、いくつかの工夫により根治術に到達することができたので報告する。(著者抄録)

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    Other Link: https://search.jamas.or.jp/default/link?pub_year=2006&ichushi_jid=J01122&link_issn=&doc_id=20060925240008&doc_link_id=10.4326%2Fjjcvs.35.281&url=https%3A%2F%2Fdoi.org%2F10.4326%2Fjjcvs.35.281&type=J-STAGE&icon=https%3A%2F%2Fjk04.jamas.or.jp%2Ficon%2F00007_3.gif

  • ウシ心膜弁による僧帽弁置換術後急性弁機能不全に対するvalve-in-valve法による再弁置換術

    立石 実, 小出 昌秋, 国井 佳文, 渡邊 一正, 大澤 幹夫

    胸部外科   59 ( 1 )   61 - 64   2006.1

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    Authorship:Lead author   Language:Japanese   Publisher:(株)南江堂  

    73歳女性.患者は既往として54歳時に僧帽弁閉鎖不全(MR)でCEP弁による僧帽弁置換術を受けた.今回,突然に胸がザーザーする感じで近医を受診,心エコーにて重度MR,中等度三尖弁逆流を認め,肺高血圧と著明な血尿より人工弁機能不全が疑われ救急搬送された.X線では心胸郭比(CTR)58%,軽度の肺うっ血,尿潜血反応(3+)を認め,心電図は洞調律であった.僧帽弁位CEP弁の機能不全と機械的溶血と診断し,緊急に人工弁置換術を行った.生体弁は後壁側中隔寄りのステント縫合部で大きく断裂し,左室内の生体弁のステントが後壁と高度に癒着,剥離が危険なため生体弁の弁輪,ステントを留置したまま生体弁のカフに機械弁を縫着した.以後,人工心肺からの離脱は容易で,尿量も体外循環中から確保され,血尿も徐々に正常化し,術後2日目に抜管となり経過は順調である

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    Other Link: https://search.jamas.or.jp/default/link?pub_year=2006&ichushi_jid=J00349&link_issn=&doc_id=20060113170013&doc_link_id=1390282763056409856&url=https%3A%2F%2Fcir.nii.ac.jp%2Fcrid%2F1390282763056409856&type=CiNii&icon=https%3A%2F%2Fjk04.jamas.or.jp%2Ficon%2F00003_2.gif

  • 乳児期の腱索断裂による僧帽弁閉鎖不全症に対するedge-to-edge法

    立石 実, 小出 昌秋, 打田 俊司, 渡邊 一正, 水上 愛弓, 武田 紹

    日本小児循環器学会雑誌   21 ( 1 )   28 - 31   2005.1

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    8ヵ月男児.高度の僧帽弁閉鎖不全症であり,edge-to-edge法(Alfieri法)による僧帽弁形成術を行い,良好な結果を得た.本例の僧帽弁閉鎖不全症は,僧帽弁の腱策断裂による前尖逸脱によるものであった.本法は自己組織のみで弁形成が可能であり,逸脱した弁尖のfree edgeを対側と縫合し,弁の開口部を2つに分けることにより,弁の開閉能を保ち,かつ全体の弁口面積を調節することで狭窄とならない術式である.体外循環が短時間で済むこと,低侵襲な手術であることなど,乳児期の重症僧帽弁閉鎖不全症にも有用であると考えられた

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    Other Link: https://search.jamas.or.jp/default/link?pub_year=2005&ichushi_jid=J02003&link_issn=&doc_id=20050202210006&doc_link_id=%2Fee7shoni%2F2005%2F002101%2F007%2F0028-0031%26dl%3D0&url=https%3A%2F%2Fwww.medicalonline.jp%2Fjamas.php%3FGoodsID%3D%2Fee7shoni%2F2005%2F002101%2F007%2F0028-0031%26dl%3D0&type=MedicalOnline&icon=https%3A%2F%2Fjk04.jamas.or.jp%2Ficon%2F00004_2.gif

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  • 女性外科医が自分らしく生きる道 Invited

    立石 実

    大阪公立大学医学部ダイバシティー講演会「やってみたいを選択できる大学に」  2025.2 

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    Event date: 2025.2

    Language:Japanese   Presentation type:Public lecture, seminar, tutorial, course, or other speech  

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  • 先天性心疾患領域の魅力 Invited

    立石 実

    第55回 日本心臓血管外科学会総会 卒後教育セミナー Basicコース  2025.2 

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    Event date: 2025.2

    Language:Japanese   Presentation type:Public lecture, seminar, tutorial, course, or other speech  

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  • Report on the current status of information dissemination on congenital heart disease through the JCPCCS website and SNS for the general public

    MinoriTateishi, Hikoro Matsui, Jun Yoshimoto, Ryoga Ochiai, Naomi Akiyama

    The 60th Annual Meeting of Japanese Society of Pediatric Cardiology and Cardiac Surgery  2024.7 

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    Event date: 2024.7

    Language:Japanese   Presentation type:Poster presentation  

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  • Important procedures that you will surely recognize, Jatene and Rastelli. Invited

    Minori Tateishi

    2024.4 

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    Event date: 2024.4

    Language:Japanese   Presentation type:Symposium, workshop panel (nominated)  

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  • Implementation of task-sharing / shifting involving multidisciplinary professionals (nurses, pharmacists, clinical engineers) Invited

    Minori Tateishi

    2023.11 

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    Event date: 2023.11

    Language:Japanese   Presentation type:Symposium, workshop panel (public)  

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  • 心外型総肺静脈還流異常を合併した無脾症候群に対する治療戦略

    立石 実, 小出 昌秋, 國井 佳文, 前田 拓也, 新堀 莉沙, 守内 大樹, 中嶌 八隅, 杉山 央, 金子 幸栄, 井上 奈緒

    日本小児循環器学会総会・学術集会抄録集  2022.7  (NPO)日本小児循環器学会

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    Event date: 2022.7

    Language:Japanese   Presentation type:Oral presentation (general)  

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  • 日本小児循環器学会COVID-19対策特別チームのこれまでの取り組み

    立石 実, 坂本 喜三郎, 山岸 敬幸, 土井 庄三郎, 豊野 学朋, 安河内 聰, 三谷 義英, 稲井 慶, 加藤 愛章, 木村 純人, 齋木 宏文, 山澤 弘州, 落合 亮太, 加藤 太一, 藤井 隆成, 白石 公, 増谷 聡, 日本循環器学会COVID-19対策特別チーム

    日本成人先天性心疾患学会雑誌  2022.1  (一社)日本成人先天性心疾患学会

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    Event date: 2022.1

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  • 無意識の偏見"unconscious bias" 心臓血管外科医の労働環境改善に必要な価値観のアップデート Invited

    立石 実

    人工臓器  2021.10  (一社)日本人工臓器学会

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    Event date: 2021.10

    Language:Japanese   Presentation type:Symposium, workshop panel (nominated)  

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  • COVID19の実態と対策 日本小児循環器学会COVID-19対策特別チームのこれまでの取り組み、および全国の修練施設アンケート調査結果報告 Invited

    立石 実

    日本小児循環器学会総会・学術集会抄録集  2021.7  (NPO)日本小児循環器学会

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    Event date: 2021.7

    Language:Japanese   Presentation type:Symposium, workshop panel (nominated)  

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  • 大動脈スイッチ手術後遠隔期の大動脈基部拡大に関する検討

    立石 実, 小出 昌秋, 國井 佳文, 奥木 聡志, 曹 宇晨, 新堀 莉沙, 中嶌 八隅, 金子 幸栄, 井上 奈緒

    日本小児循環器学会雑誌  2020.11  (NPO)日本小児循環器学会

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    Event date: 2020.11

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  • 当院におけるIMPELLAおよびハートチーム導入前後の治療成績の比較検討

    立石 実, 小出 昌秋, 國井 佳文, 奥木 聡志, 櫻井 陽介, 新堀 莉沙, 守内 大樹

    日本胸部外科学会定期学術集会  2020.10  (一社)日本胸部外科学会

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    Event date: 2020.10

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  • 大動脈スイッチ手術後遠隔期の大動脈弁閉鎖不全に関する検討

    立石 実, 小出 昌秋, 國井 佳文, 奥木 聡志, 櫻井 陽介, 新堀 莉沙, 守内 大樹

    日本胸部外科学会定期学術集会  2020.10  (一社)日本胸部外科学会

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    Event date: 2020.10

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  • ファロー四徴症術後遠隔期の肺動脈弁置換における弁の選択

    立石 実, 小出 昌秋, 國井 佳文, 奥木 聡志, 曹 宇晨, 新堀 莉沙, 中嶌 八隅, 金子 幸栄, 井上 奈緒

    日本成人先天性心疾患学会雑誌  2020.1  (一社)日本成人先天性心疾患学会

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    Event date: 2020.1

    Language:Japanese  

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  • 人工臓器学会から発信する「働き方改革」 心臓外科医のリアルワールド 心臓外科医の立場から考える「働き方改革」 Invited

    立石 実

    人工臓器  2019.10  (一社)日本人工臓器学会

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    Event date: 2019.10

    Language:Japanese   Presentation type:Symposium, workshop panel (nominated)  

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  • 成人先天性心疾患術後患者における感染性心内膜炎の外科的治療の課題

    立石 実, 小出 昌秋, 國井 佳文, 渡邊 一正, 奥木 聡志, 櫻井 陽介, 曹 宇晨, 中嶌 八隅, 金子 幸栄, 井上 奈緒, 森 善樹

    日本小児循環器学会雑誌  2019.6  (NPO)日本小児循環器学会

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    Event date: 2019.6

    Language:Japanese  

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  • フィジシャンアシスタントは医師の過重労働解決の切り札となりうるか 女性外科医としてPAに期待すること Invited

    立石 実, 小出 昌秋, 北本 憲永

    医療の質・安全学会誌  2018.10  (一社)医療の質・安全学会

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    Event date: 2018.10

    Language:Japanese   Presentation type:Symposium, workshop panel (nominated)  

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  • 補助循環の最新治療と安全管理 Invited

    立石 実

    日本クリティカルケア看護学会学術集会抄録集  2018.6  (一社)日本クリティカルケア看護学会

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    Event date: 2018.6

    Language:Japanese   Presentation type:Public lecture, seminar, tutorial, course, or other speech  

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  • 移行期医療の新たな取り組み、YouTubeチャネルによる動画配信「Living With Heart~みんなの生き方~」

    立石 実, 猪又 竜, 落合 亮太

    日本成人先天性心疾患学会雑誌  2018.1  (一社)日本成人先天性心疾患学会

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    Event date: 2018.1

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  • 植込み型補助人工心臓EVAHEARTにおけるドライブライン管理法の考察

    立石 実, 西中 知博, 市原 有起, 駒ヶ嶺 正英, 斎藤 聡, 山崎 健二, 新浪 博士, 布田 伸一

    適応医学  2017.11  日本適応医学会

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    Event date: 2017.11

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  • 臓器移植法20年を考える 医療施設からの臓器提供の推進 「患者との協働」の視点で臓器提供の推進を

    立石 実, 齋藤 聡, 西中 知博, 駒ヶ嶺 正英, 勝部 健, 瀬田 博允, 片桐 絢子, 中前 亨介, 布田 伸一, 山崎 健二

    移植  2017.8  (一社)日本移植学会

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    Event date: 2017.8

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  • 植込型補助人工心臓治療中に心臓移植適応基準から外れた3症例の経験を通じて 事前指示書や終末期医療のあり方を考える

    立石 実, 齋藤 聡, 西中 知博, 駒ヶ嶺 正英, 勝部 健, 瀬田 博允, 片桐 絢子, 中前 亨介, 布田 伸一, 山崎 健二

    移植  2017.8  (一社)日本移植学会

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    Event date: 2017.8

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  • 小児重症心不全治療 小児領域における補助人工心臓の適応と限界 Invited

    立石 実

    日本小児循環器学会雑誌  2017.7  (NPO)日本小児循環器学会

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    Event date: 2017.7

    Language:Japanese   Presentation type:Symposium, workshop panel (nominated)  

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  • VADのドライブライン感染における、金属アーチファクト低減アルゴリズムCTの有用性

    立石 実, 齋藤 聡, 梅原 伸大, 勝部 健, 柏村 千尋, 小林 慶, 村上 弘典, 山崎 健二

    日本心臓血管外科学会学術総会抄録集  2017.2  (NPO)日本心臓血管外科学会

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    Event date: 2017.2

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  • 心臓 心移植後の社会復帰について 補助人工心臓(VAD)植込みおよび心移植の就労率に影響する患者背景因子の検討

    立石 実, 齋藤 聡, 梅原 伸大, 勝部 健, 瀧口 洋司, 村上 弘典, 西中 知博, 布田 伸一, 山崎 健二

    移植  2016.9  (一社)日本移植学会

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    Event date: 2016.9

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  • Jatene術後、Freestyle弁によるAVR術後の生体弁機能不全に対する再手術の1例

    立石 実, 長嶋 光樹, 松村 剛毅, 上松 耕太, 大倉 正寛, 前田 拓也, 秋山 章, 平松 健司, 山崎 健二

    日本成人先天性心疾患学会雑誌  2016.1  (一社)日本成人先天性心疾患学会

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    Event date: 2016.1

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  • Fontan手術適応限界症例に対するFenestrated TCPCの治療成績

    立石 実, 長嶋 光樹, 平松 健司, 松村 剛毅, 小嶋 愛, 鈴木 憲治, 腰山 宏, 増田 憲保, 磯村 彰吾, 山崎 健二, 中西 敏雄

    日本小児循環器学会雑誌  2014.6  (NPO)日本小児循環器学会

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    Event date: 2014.6

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  • 当院におけるFontan術式、治療戦略と工夫の歴史的変遷

    立石 実, 長嶋 光樹, 平松 健司, 松村 剛毅, 小嶋 愛, 渕上 泰, 飯塚 慶, 柏村 千尋, 服部 将士

    日本心臓血管外科学会雑誌  2014.1  (NPO)日本心臓血管外科学会

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    Event date: 2014.1

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  • 右室流出路再建後遠隔期狭窄における狭窄形態と血流動態からみた重症度評価と治療戦略

    立石 実, 板谷 慶一, 宮崎 翔平, 長嶋 光樹, 平松 健司, 松村 剛毅, 小沼 武司, 豊田 泰幸, 中山 祐樹, 山田 有希子, 加久 雄史, 早川 美奈子, 梅津 光生, 斎藤 加代子, 山崎 健二

    日本心臓血管外科学会雑誌  2013.2  (NPO)日本心臓血管外科学会

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    Event date: 2013.2

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  • 自己組織が介在したRastelli型手術の長期遠隔成績の検討

    立石 実, 平松 健司, 松村 剛毅, 小沼 武司, 杉本 晃一, 大倉 正寛, 豊田 泰幸

    日本小児循環器学会雑誌  2012.6  (NPO)日本小児循環器学会

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    Event date: 2012.6

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  • 中心肺動脈欠損または高度低形成を伴うMAPCA合併心奇形に対する一期的両側UFの有用性

    立石 実, 山岸 正明, 宮崎 隆子, 前田 吉宣, 谷口 智史, 田畑 雄一, 夜久 均

    日本心臓血管外科学会雑誌  2009.3  (NPO)日本心臓血管外科学会

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    Event date: 2009.3

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  • Lamberti法+BDGを施行したDILVの1例

    立石 実, 星野 修一, 外川 正海, 上田 哲之, 西谷 泰, 畑崎 喜芳, 中山 祐子, 太田 邦雄, 斎藤 剛克, 坂詰 忍

    日本小児循環器学会雑誌  2007.3  (NPO)日本小児循環器学会

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    Event date: 2007.3

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  • 末梢性肺動脈狭窄を有し,高肺血管抵抗にて手術適応外と思われた純型肺動脈閉鎖の年長児に対して術中肺動脈ステント留置を併せて行いFontan手術を行い得た1例

    立石 実, 小出 昌秋, 国井 佳史, 渡邊 一正, 本田 雄氣, 武田 紹

    日本小児循環器学会雑誌  2006.3  (NPO)日本小児循環器学会

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    Event date: 2006.3

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  • 頸部血管閉塞性病変を有するファロー四徴症に対して頸部動脈再建術を行った1例

    立石 実, 小出 昌秋, 国井 佳史, 渡邊 一正, 水上 愛弓, 武田 紹

    日本小児循環器学会雑誌  2006.3  (NPO)日本小児循環器学会

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    Event date: 2006.3

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  • 自己組織が介在したRastelli型手術の長期遠隔成績の検討

    立石 実, 黒澤 博身, 長津 正芳, 新岡 俊治, 石山 雅邦, 森嶋 克昌, 小坂 由道, 松村 剛毅, 山本 昇, 石橋 信之

    日本心臓血管外科学会雑誌  2006.3  (NPO)日本心臓血管外科学会

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    Event date: 2006.3

    Language:Japanese  

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  • 22q11.2欠失に伴う異型胸部大動脈縮窄症の2治験例

    立石 実, 黒澤 博身, 新岡 俊治, 長津 正芳, 石山 雅邦, 森嶋 克昌, 山本 昇, 小坂 由道, 松村 剛毅, 石橋 信之

    日本胸部外科学会関東甲信越地方会要旨集  2006.2  日本胸部外科学会-関東甲信越地方会

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    Event date: 2006.2

    Language:Japanese  

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  • 平均肺動脈圧22mmHg以上のHigh Risk症例におけるFontan手術とSeptation手術の比較検討

    立石 実, 黒澤 博身, 長津 正芳, 新岡 俊治, 石山 雅邦, 森嶋 克昌, 小坂 由道, 松村 剛毅, 山本 昇, 小沼 武司, 上松 耕太, 遊佐 裕明, 杉浦 唯久, 宮本 真嘉, 大森 一史

    The Japanese Journal of THORACIC AND CARDIOVASCULAR SURGERY  2005.9  (一社)日本胸部外科学会

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    Event date: 2005.9

    Language:Japanese  

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  • VSD(infundibular muscular type)+ARに対しRoss手術を行なった2例

    立石 実, 黒澤 博身, 長津 正芳, 新岡 俊治, 石山 雅邦, 森嶋 克昌, 小坂 由道, 松村 剛毅, 山本 昇

    日本胸部外科学会関東甲信越地方会要旨集  2005.9  日本胸部外科学会-関東甲信越地方会

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    Event date: 2005.9

    Language:Japanese  

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  • 無脾症における総肺静脈還流異常のMD-CTによる術前評価

    立石 実, 小出 昌秋, 国井 佳文, 渡邊 一正, 水上 愛弓, 武田 紹

    日本小児循環器学会雑誌  2005.5  (NPO)日本小児循環器学会

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    Event date: 2005.5

    Language:Japanese  

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  • TAPVCの診断にマルチスライスCTが有用であったaspleniaの2治験例

    立石 実, 小出 昌秋, 渡邊 一正, 国井 佳文, 水上 愛弓, 武田 紹

    日本小児循環器学会雑誌  2005.3  (NPO)日本小児循環器学会

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    Event date: 2005.3

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  • CEP弁によるMVR後19年目に発症した急性弁機能不全に対しvalve-in-valve法にて人工弁再弁置換術を行った1例

    立石 実, 小出 昌秋, 国井 佳文, 渡邊 一正

    日本胸部外科学会関東甲信越地方会要旨集  2005.2  日本胸部外科学会-関東甲信越地方会

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    Event date: 2005.2

    Language:Japanese  

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  • 新生児・乳幼児に対する全身麻酔呼吸停止下MD-CTと血管造影検査との有用性の比較検討

    立石 実, 小出 昌秋, 国井 佳文, 渡邊 一正

    日本心臓血管外科学会雑誌  2005.1  (NPO)日本心臓血管外科学会

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    Event date: 2005.1

    Language:Japanese  

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  • 頸部血管閉塞性病変及び特異な形態の大動脈縮窄を伴ったファロー四徴症に対して頸動脈再建術を行った1例

    立石 実, 小出 昌秋, 国井 佳文, 渡邊 一正

    日本胸部外科学会関東甲信越地方会要旨集  2004.9  日本胸部外科学会-関東甲信越地方会

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    Event date: 2004.9

    Language:Japanese  

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  • 新生児期に根治術を行った右肺動脈上行大動脈起始症の2治験例

    立石 実, 小出 昌秋, 打田 俊司, 水上 愛弓, 武田 紹

    日本小児循環器学会雑誌  2004.7  (NPO)日本小児循環器学会

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    Event date: 2004.7

    Language:Japanese  

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  • 大動脈弁置換術後人工弁心内膜炎に対してRoss手術を施行した1例

    立石 実, 黒澤 博身, 遠藤 真弘, 山嵜 健二, 華山 直二, 津久井 宏行, 石橋 信之

    The Japanese Journal of THORACIC AND CARDIOVASCULAR SURGERY  2004.3  (一社)日本胸部外科学会

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    Event date: 2004.3

    Language:Japanese  

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  • 特異な形態の大動脈縮窄を伴ったファロー四徴症に対するカテーテル検査中に大動脈解離をきたし,緊急的に人工血管によるExtra-anatomical Bypassを行った1例

    立石 実, 小出 昌秋, 打田 俊司, 渡邊 一正

    The Japanese Journal of THORACIC AND CARDIOVASCULAR SURGERY  2004.3  (一社)日本胸部外科学会

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    Event date: 2004.3

    Language:Japanese  

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  • 右肺動脈上行大動脈起始症の2手術例

    立石 実, 小出 昌秋, 打田 俊司, 水上 愛弓, 武田 紹

    The Japanese Journal of THORACIC AND CARDIOVASCULAR SURGERY  2004.3  (一社)日本胸部外科学会

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    Event date: 2004.3

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  • 成人開心術における体外循環中のhANP低用量持続投与は有用か?

    立石 実, 小出 昌秋, 打田 俊司, 渡邊 一正

    日本心臓血管外科学会雑誌  2004.2  (NPO)日本心臓血管外科学会

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    Event date: 2004.2

    Language:Japanese  

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  • 僧帽弁位に使用した生体弁(Hancock,Ionescu-Shiley,Carpentier-Edwards)の長期遠隔成績と,摘出弁の形態学的比較

    立石 実, 小出 昌秋, 打田 俊司, 大澤 幹夫

    The Japanese Journal of THORACIC AND CARDIOVASCULAR SURGERY  2003.10  (一社)日本胸部外科学会

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    Event date: 2003.10

    Language:Japanese  

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  • 咳嗽を契機に発症したと考えられた冠動脈穿孔の一例

    立石 実, 中島 崇智, 篠田 尚克, 山内 貴雄, 小金井 佐知子, 中村 彩子, 河口 正雄, 江郷 洋一

    Circulation Journal  2002.4  (一社)日本循環器学会

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    Event date: 2002.4

    Language:Japanese  

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  • 右頸部大動脈弓に弓部大動脈狭窄とKommerell憩室を伴った症例に対し狭窄解除術を行った1例

    立石 実, 今井 康晴, 瀬尾 和宏, 青木 満, 新岡 俊治, 平松 健司, 太田 淳, 濱脇 正好, 萩野 生男, 柏木 潤一

    Japanese Circulation Journal  2001.4  (一社)日本循環器学会

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    Event date: 2001.4

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  • Tips for cardiovascular surgeons to keep it working longer - Diversity in cardiovascular surgeons. Invited

    Minori Tateishi

    2024.3 

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    Language:Japanese   Presentation type:Public lecture, seminar, tutorial, course, or other speech  

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Research Projects

  • 先天性心疾患を主体とする小児期発症の心血管難治性疾患の救命率の向上、円滑な移行医療、成人期以降の予後改善を目指した総合的研究

    Grant number:24FC02201  2024.3 - 2027.3

    厚生労働省 難治性疾患政策研究事業 

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    Authorship:Coinvestigator(s) 

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  • Development, Analyze and Clinical Use of Tissue Engineering Large Diameter Autografts

    Grant number:17591490  2005 - 2006

    Japan Society for the Promotion of Science  Grants-in-Aid for Scientific Research  Grant-in-Aid for Scientific Research (C)

    YAMAMOTO Noboru, SHIN'OKA Toshiharu, KUROSAWA Hiromi, MATSUMURA Goki

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    Grant amount:\3700000 ( Direct Cost: \3700000 )

    This study demonstrates the evaluation of tissue-engineered vascular autografts (TEVAs) constructed with autologous mononuclear-bone marrow cells (MN-BMCs) and a biodegradable scaffold using a canine inferior vena cava (IVC) model.
    MN-BMCs were obtained from a dog and seeded onto a biodegradable tubular scaffold consisting of polyglycolide fiber and poly(1-lactide-co-ε-caprolactone) sponge. This scaffold was implanted in the IVC of the same dog on the day of surgery. TEVAs were analyzed biochemically, biomechanically and histologically after implantation. When TEVAs were explanted and stimulated with acetylcholine at 1 month, they dose dependently produced nitrates and nitrites. N^G-nitro-L-arginine methylester significantly inhibited these reactions. On the stimulation by acetylcholine, factor VIII-positive cells of TEVAs produced eNOS proteins, and the ratio of eNOS/s17 mRNA were similar among native IVC, 1-and 3-months TEVAs. TEVAs had similar biochemical properties and wall thickness as native IVC at 6 months after implantation, and tolerated venous pressure well without any problems such as calcification.
    These results indicate that TEVAs are biocompatible material with functional endothelial cells and biomechanical properties without unwanted side-effects.

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Teaching Experience

  • 外科(先天性心疾患)

    2023.9 - 2023.10 Institution:横浜市立大学 医学部3年

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Social Activities

  • Living With Heart 〜The Each Way of Living〜

    Role(s): Lecturer

    Yokohama City University  2024.11

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    Type:Science festival

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  • The Importance of Diversity and Task Sharing - Survival Strategies for Endangered Surgeons in an Era of Work style reform.

    Role(s): Lecturer

    Japanese Council of designated teaching institutions for Cardio-Thoracic Surgery  2024.6

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    Type:Seminar, workshop

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  • ドクターの"もやもや話" 〜医療者だってもやもやしてるよ〜

    Role(s): Lecturer

    一般社団法人ピーペック みんなで作ろう、これからの医療 with Heart プロジェクト  心臓病のもやもやを語る夜  2024.3

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    Type:Lecture

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  • ダイバシティとタスクシェアの重要性 〜働き方改革時代における、絶滅危惧種の外科医の生存戦略〜

    Role(s): Panelist

    大阪公立大学大学院 肝胆膵外科学 / 共催:ジョンソン・エンド・ジョンソン株式会社  第2回 外科医療の「新世界」セミナー  2024.2

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    Type:Seminar, workshop

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  • 先天性心疾患診療で注意すべき合併症

    Role(s): Lecturer

    後援: 日本循環器協会、共催: ヤンセンファーマ / 日本新薬株式会社  日本循環器協会共催 ACHD疾患啓発Webセミナー  2023.10

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    Type:Seminar, workshop

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