Updated on 2026/06/18

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写真a

 
Akifumi Ijuin
 
Organization
YCU Medical Center Reproductive Medicine Center Assistant Professor
Title
Assistant Professor
Profile

2011年 横浜市立大学医学部医学科卒業

2016年 産婦人科専門医

2019年 横浜市立大学医学部付属市民総合医療センター総合周産期母子医療センター/生殖医療センター 助教、横浜市立大学大学院医学研究科博士課程医科学専攻入学

2023年 横浜市立大学医学部付属市民総合医療センター 臨床研究部/生殖医療センター婦人科 助教

2025年 横浜市立大学医学部付属市民総合医療センター 生殖医療センター婦人科/遺伝子診療科 助教

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Research Areas

  • Life Science / Obstetrics and gynecology  / Developmental biology, embryology

Papers

  • Spontaneous miscarriage after intracytoplasmic sperm injection with frozen sperm of patients with testicular germ cell tumour. International journal

    Haru Hamada, Akifumi Ijuin, Tomonari Hayama, Naoki Tsuchiya, Sumiko Sueyoshi, Misaki Toda, Ai Miyakoshi, Mayuko Kurumizaka, Marina Saito, Yuki Oike, Hiroe Ueno, Shinnosuke Kuroda, Kazumi Takeshima, Teppei Takeshima, Shin Saito, Ryoko Asano, Taichi Mizushima, Yasushi Yumura, Hideya Sakakibara, Etsuko Miyagi, Miki Tanoshima, Mariko Murase

    BJU international   2026.6

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    OBJECTIVE: To clarify the impact of chromosomal aberrations on the offspring of patients with testicular germ cell tumour (TGCT) by evaluating the outcomes of intracytoplasmic sperm injection (ICSI). PATIENTS AND METHODS: Under the ethical review of Yokohama City University, 12 patients with TGCT and 25 with non-TGCT cancer who had cryopreserved sperm for ICSI for fertility preservation between 1 April 2014 and 31 March 2023 were enrolled. For 198 oocytes from the TGCT group, 480 oocytes from the non-TGCT group, fertilisation, embryo viability, pregnancy, and spontaneous miscarriage rates were examined. RESULTS: Females who received ICSI from patients with TGCT showed a significantly higher spontaneous miscarriage rate than those who received ICSI from patients with non-TGCT cancer (43.8% vs 9.1%, respectively, P < 0.05), with no significant between-group difference in the pregnancy rate. In the TGCT group, three cases of recurrent pregnancy loss and recurrent implantation failure were reported. The high spontaneous miscarriage rate in the TGCT group can be attributed to chromosomal abnormalities or DNA fragmentation in the sperm of patients with TGCT. CONCLUSION: Natural conception may be an option for patients who have completed TGCT treatment and have adequate sperm. However, when semen parameters do not recover sufficiently, assisted reproductive technologies may be considered, including, where possible, the use of post-treatment sperm not affected by TGCT rather than pre-treatment sperm collected during tumour-bearing state. In selected cases, pre-implantation genetic testing for aneuploidy may also be considered.

    DOI： 10.1111/bju.70332

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  • Abnormal PAR1/2 Number Can Influence Effector T Cell Subsets in Turner Syndrome. International journal

    Ai Miyakoshi, Sumiko Sueyoshi, Akifumi Ijuin, Haru Hamada, Mayuko Nishi, Shiori Tochihara, Marina Saito, Hiroe Ueno, Michi Kasai, Shin Saito, Ryoko Asano, Taichi Mizushima, Etsuko Miyagi, Mariko Murase, Miki Tanoshima, Hideya Sakakibara, Tomonari Hayama

    Molecular syndromology   1 - 11   2025.5

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    INTRODUCTION: Turner syndrome is a complicated gonadal insufficiency, infertility, and endocrine disease caused by the partial to complete loss of one X chromosome. Women with Turner syndrome have been reported to show altered effector T-cell subgroups; however, the relationship between T-cell subgroups and chromosome type remains unknown. METHODS: In this study, we investigated immune abnormalities and karyotypes of Turner syndrome. Using flowcytometry, we examined the T-cell subsets of 20 women with Turner syndrome and 23 women serving as controls (without recurrent pregnancy loss), between July 2021 and June 2022. Background data of the women with Turner syndrome were also collected. RESULTS: Significantly lower levels of helper T-cells 1 and 2 were observed in women with Turner syndrome than in the control group (4.5 ± 2.88 vs. 8.54 ± 4.45, p < 0.05, 0.56 ± 0.38 vs. 0.97 ± 0.48, p < 0.05, respectively). With respect to karyotypes, deletion of a specific region, pseudoautosomal region 2, which typically escapes X-inactivation, might influence regulatory T cells (Treg) levels as copy number of PAR2 and Treg rate were positively correlated (r = 0.76). CONCLUSION: Individuals with Turner syndrome showed an altered T-cell subset, which might be caused by the deletion of a specific part of the X chromosome, pseudoautosomal region 2. This finding suggests that women with Turner syndrome in a specific karyotype show altered T-cell subsets, and more cases are needed to determine whether these T-cell changes could influence pregnancy outcomes.

    DOI： 10.1159/000546378

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  • Single sperm karyotyping of testicular sperm in non-obstructive and obstructive azoospermia using next generation sequencing. International journal

    Sumiko Sueyoshi, Akifumi Ijuin, Hiroe Ueno, Ai Miyakoshi, Haru Hamada, Misaki Toda, Naoki Tsuchiya, Miki Tanoshima, Mayuko Kurumizaka, Marina Saito, Yuki Oike, Kazumi Takeshima, Teppei Takeshima, Shinnosuke Kuroda, Yasushi Yumura, Shin Saito, Ryoko Asano, Taichi Mizushima, Etsuko Miyagi, Hideya Sakakibara, Hiroki Kurahashi, Akira Yanagihara, Mariko Murase, Tomonari Hayama

    PloS one   20 ( 12 )   e0338222   2025

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    The sperm of infertile men have higher rates of chromosomal abnormalities than those of fertile men. Miscarriage rate is also higher following testicular sperm extraction combined with intracytoplasmic sperm injection (TESE-ICSI). Sperm chromosomal abnormalities are assumed to be the cause of miscarriages. Previous testicular sperm karyotyping studies have only examined a few selected chromosomes using fluorescence in situ hybridization. The aim of this study was to provide a more detailed analysis of sperm karyotyping by analyzing all chromosomes using next-generation sequencing (NGS) in clinically usable testicular sperm. Sperm discarded after clinical use was collected for NGS. Additionally, sperm were individually collected by micromanipulation from patients with obstructive azoospermia (OA) and non-obstructive azoospermia (NOA) who underwent TESE-ICSI. For comparison, ejaculated sperm from control and balanced translocation (BT) carriers were examined. Karyotyping was performed on individual sperm cells using NGS. The number of normal and aberrant sperm was compared. Seventeen patients participated in this study: control (n = 4), BT (n = 3), OA (n = 5), and NOA (n = 5). Ten sperm samples per patient were analyzed. The total acquisition rate for single sperm karyotyping was 85% (145/170). Karyotyping of sperm from the BT group revealed sperm with unbalanced chromosomes derived from carrier translocations. Among the NOA group, 7/41 (17%) sperm samples exhibited aberrant karyotypes, whereas no aberrant sperm were identified in the control and OA groups. Individual differences were observed in the frequency of sperm chromosomal abnormalities among patients with NOA. In conclusion, sperm chromosomal abnormalities are frequently observed in patients with NOA even after sperm selection for clinical use. As the frequency of chromosomal abnormalities varies among patients with NOA, single sperm sequencing may help identify patients with NOA most likely to benefit from PGT-A.

    DOI： 10.1371/journal.pone.0338222

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  • 精子不動症に対しTESE-ICSIを施行した3症例

    三村 昇, 竹島 徹平, 青木 駿, 齋藤 智樹, 苅部 樹里衣, 黒田 晋之介, 古目谷 暢, 戸田 美咲, 末吉 寿実鼓, 濱田 春, 伊集院 昌郁, 宮腰 藍衣, 葉山 智工, 齋藤 満里奈, 栃原 しおり, 上野 寛枝, 村瀬 真理子, 湯村 寧

    日本生殖医学会雑誌   68 ( 4 )   469 - 469   2023.10

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  • Mitochondrial DNA mutations can influence the post-implantation development of human mosaic embryos Reviewed

    Akifumi Ijuin, Hiroe Ueno, Tomonari Hayama, Shunsuke Miyai, Ai Miyakoshi, Haru Hamada, Sumiko Sueyoshi, Shiori Tochihara, Marina Saito, Haruka Hamanoue, Teppei Takeshima, Yasushi Yumura, Etsuko Miyagi, Hiroki Kurahashi, Hideya Sakakibara, Mariko Murase

    Frontiers in Cell and Developmental Biology   11   2023.8

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    Authorship：Lead author   Language：English   Publishing type：Research paper (scientific journal)   Publisher：Frontiers Media SA  

    Introduction: Several healthy euploid births have been reported following the transfer of mosaic embryos, including both euploid and aneuploid blastomeres. This has been attributed to a reduced number of aneuploid cells, as previously reported in mice, but remains poorly explored in humans. We hypothesized that mitochondrial function, one of the most critical factors for embryonic development, can influence human post-implantation embryonic development, including a decrease of aneuploid cells in mosaic embryos.

    Methods: To clarify the role of mitochondrial function, we biopsied multiple parts of each human embryo and observed the remaining embryos under in vitro culture as a model of post-implantation development (n = 27 embryos). Karyotyping, whole mitochondrial DNA (mtDNA) sequencing, and mtDNA copy number assays were performed on all pre- and post-culture samples.

    Results: The ratio of euploid embryos was significantly enhanced during in vitro culture, whereas the ratio of mosaic embryos was significantly reduced. Furthermore, post-culture euploid and culturable embryos had significantly few mtDNA mutations, although mtDNA copy numbers did not differ.

    Discussion: Our results indicate that aneuploid cells decrease in human embryos post-implantation, and mtDNA mutations might induce low mitochondrial function and influence the development of post-implantation embryos with not only aneuploidy but also euploidy. Analyzing the whole mtDNA mutation number may be a novel method for selecting a better mosaic embryo for transfer.

    DOI： 10.3389/fcell.2023.1215626

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  • The acceptance to germline gene therapy increased during COVID-19 pandemic among Japanese medical students. Reviewed International journal

    Akifumi Ijuin, Tomonari Hayama, Hideya Sakakibara

    The journal of obstetrics and gynaecology research   2022.3

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    DOI： 10.1111/jog.15246

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  • Fertility preservation immediately after therapeutic abortion results in multiple normal follicular growth with the absence of mature oocytes due to early luteinization: a case report and literature review. International journal

    Haru Hamada, Tomonari Hayama, Akifumi Ijuin, Ai Miyakoshi, Michi Kasai, Shiori Tochihara, Marina Saito, Mayuko Nishi, Hiroe Ueno, Mizuki Yamamoto, Mitsuru Komeya, Yasushi Yumura, Hideya Sakakibara, Etsuko Miyagi, Mariko Murase

    Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology   37 ( 11 )   1050 - 1053   2021.11

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    Cancer therapy has priority over fertility preservation. The time available for fertility preservation in patients with cancer is often very limited and depends on the condition of the underlying disease. This case report presents the results of two rounds of controlled ovarian stimulations (COSs) performed after an induced abortion. The patient had mixed phenotype acute leukemia diagnosed during early pregnancy and underwent a surgical abortion, followed by ovarian stimulation using urinary follicle-stimulating hormone (uFSH) and gonadotropin-releasing hormone (GnRH) agonists. Oocyte retrieval was subsequently performed for oocyte cryopreservation. Despite good hormonal and ultrasonic follicular growth, no oocytes were obtained. During a second COS performed at a low human chorionic gonadotropin (hCG) level (less than 100 IU/L), several mature oocytes were obtained, suggesting that higher hCG levels during COS induce the absence of mature oocytes during normal follicular growth. It is recommended to start COS post-abortion after confirming a low hCG level while considering the timing of cancer treatment.

    DOI： 10.1080/09513590.2021.1950135

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  • 卵巣組織凍結方法の比較検討

    宮腰 藍衣, 濱田 春, 葉山 智工, 西 真裕子, 齋藤 満里奈, 上野 寛枝, 山本 みずき, 伊集院 昌郁, 榊原 秀也, 宮城 悦子, 村瀬 真理子

    日本生殖医学会雑誌   65 ( 4 )   419 - 419   2020.11

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  • 新鮮胚移植における2 cell checkの有用性

    齋藤 満里奈, 西 真裕子, 上野 寛枝, 山本 みずき, 濱田 春, 伊集院 昌郁, 宮腰 藍衣, 葉山 智工, 黒田 晋之介, 竹島 徹平, 湯村 寧, 村瀬 真理子, 榊原 秀也, 宮城 悦子

    日本生殖医学会雑誌   65 ( 4 )   399 - 399   2020.11

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  • 卵子成熟過程における活性酸素暴露が胚体内細胞に与える影響

    上野 寛枝, 伊集院 昌郁, 葉山 智工, 宮腰 藍衣, 山本 みずき, 齋藤 満里奈, 西 真裕子, 濱田 春, 黒田 晋之介, 竹島 徹平, 湯村 寧, 宮城 悦子, 榊原 秀也, 村瀬 真理子

    日本生殖医学会雑誌   65 ( 4 )   364 - 364   2020.11

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  • 凍結融解胚移植における自然周期とホルモン補充周期の違いによる妊娠率の季節変動

    西 真裕子, 齋藤 満里奈, 上野 寛枝, 栃原 しおり, 山本 みずき, 濱田 春, 宮腰 藍衣, 葉山 智工, 伊集院 昌郁, 湯村 寧, 宮城 悦子, 榊原 秀也, 村瀬 真理子

    日本生殖医学会雑誌   65 ( 4 )   407 - 407   2020.11

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  • 白血病のため人工妊娠中絶直後に妊孕性温存胚卵子凍結目的で卵巣刺激開始したが採卵不能であった一例

    濱田 春, 伊集院 昌郁, 宮腰 藍衣, 葉山 智工, 栃原 しおり, 齋藤 満里奈, 西 真裕子, 上野 寛枝, 山本 みずき, 榊原 秀也, 宮城 悦子, 村瀬 真理子

    日本生殖医学会雑誌   65 ( 4 )   419 - 419   2020.11

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  • ヒト胚遺伝子治療の臨床応用に対する医学生の意識調査

    葉山 智工, 伊集院 昌郁, 濱田 春, 宮腰 藍衣, 古目谷 暢, 竹島 徹平, 黒田 晋之介, 湯村 寧, 村瀬 真理子, 宮城 悦子, 榊原 秀也

    日本生殖医学会雑誌   65 ( 4 )   352 - 352   2020.11

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  • 腹腔鏡下副角子宮切除後に体外受精により妊娠・分娩に至った1例

    宮腰 藍衣, 伊集院 昌郁, 葉山 智工, 村瀬 真理子, 榊原 秀也, 宮城 悦子

    神奈川産科婦人科学会誌   57 ( 1 )   63 - 68   2020.9

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  • 院内e learningによる妊孕性温存治療の啓発効果

    湯村 寧, 村瀬 真理子, 葉山 智工, 竹島 徹平, 黒田 晋之介, 宮腰 藍衣, 伊集院 昌郁, 星 るり子, 和田 伸子

    日本がん・生殖医療学会誌   3 ( 1 )   104 - 104   2020.1

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  • Prenatal diagnosis of Fraser syndrome caused by novel variants of FREM2. International journal

    Shoko Ikeda, Chika Akamatsu, Akifumi Ijuin, Ami Nagashima, Megumi Sasaki, Akihiko Mochizuki, Hiromi Nagase, Yumi Enomoto, Yukiko Kuroda, Kenji Kurosawa, Hiroshi Ishikawa

    Human genome variation   7   32 - 32   2020

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    Fraser syndrome (FS) involves multiple malformations and has a 25% recurrence risk among siblings. However, these malformations are difficult to detect prenatally, hampering prenatal diagnosis. Here, we describe a fetus with FS diagnosed using ultrasonography. Ultrasonography revealed congenital high airway obstruction syndrome and renal agenesis. Syndactyly of both hands and cryptophthalmos were noted postnatally, and the diagnosis was confirmed by genetic analysis, which showed novel compound heterozygous variants of FREM2.

    DOI： 10.1038/s41439-020-00119-5

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  • 腹腔鏡下副角子宮切除後に妊娠に至った一例

    宮腰 藍衣, 伊集院 昌郁, 葉山 智工, 齋藤 満里奈, 西 真裕子, 上野 寛枝, 山本 みずき, 榊原 秀也, 宮城 悦子, 村瀬 真理子

    日本生殖医学会雑誌   64 ( 4 )   362 - 362   2019.10

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  • TESE-ICSIにおけるICSI施行時間の検討

    上野 寛枝, 山本 みずき, 齋藤 満里奈, 西 真裕子, 宮腰 藍衣, 葉山 智工, 伊集院 昌郁, 湯村 寧, 宮城 悦子, 榊原 秀也

    日本生殖医学会雑誌   64 ( 4 )   386 - 386   2019.10

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  • 当院における性腺毒性中リスク化学療法後の妊娠転帰

    伊集院 昌郁, 宮腰 藍衣, 葉山 智江, 齋藤 満里奈, 西 真裕子, 上野 寛枝, 山本 みずき, 宮城 悦子, 榊原 秀也, 村瀬 真理子

    日本生殖医学会雑誌   64 ( 4 )   437 - 437   2019.10

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  • 凍結融解胚移植における2 cell checkの有用性

    齋藤 満里奈, 西 真裕子, 上野 寛枝, 山本 みずき, 伊集院 昌郁, 宮腰 藍衣, 葉山 智工, 湯村 寧, 宮城 悦子, 榊原 秀也, 村瀬 真理子

    日本生殖医学会雑誌   64 ( 4 )   414 - 414   2019.10

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  • 凍結胚盤胞移植における年齢層別にみた融解後の胚の回復率および妊娠率についての検討

    西 真裕子, 齋藤 満里奈, 上野 寛枝, 山本 みずき, 伊集院 昌郁, 宮腰 藍衣, 葉山 智工, 湯村 寧, 宮城 悦子, 榊原 秀也, 村瀬 真理子

    日本生殖医学会雑誌   64 ( 4 )   424 - 424   2019.10

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  • Teriparatide and denosumab treatment for pregnancy and lactation-associated osteoporosis with multiple vertebral fractures: A case study. Reviewed International journal

    Akifumi Ijuin, Hiromi Yoshikata, Ryoko Asano, Taku Tsuburai, Ritsuko Kikuchi, Hideya Sakakibara

    Taiwanese journal of obstetrics & gynecology   56 ( 6 )   863 - 866   2017.12

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    OBJECTIVE: Pregnancy and lactation-associated osteoporosis (PLO) is a rare disease, which can lead to vertebral fractures in women of reproductive age. No treatment strategy for PLO has been established. Here we report a case of PLO treated with teriparatide followed by denosumab, in which remarkable improvement in bone mineral density (BMD) was achieved. CASE REPORT: A 27-year-old woman experienced severe back pain two weeks after her first delivery. PLO was diagnosed from her low BMD and multiple vertebral compression fractures. She was treated with teriparatide for 6 months, followed by denosumab. After 1 year, her BMD increase from baseline was 16.5% in L2∼4 and her pain had been relieved. CONCLUSION: In addition to weaning, administration of teriparatide followed by denosumab led to remarkable improvement in the patient's symptoms and BMD. Therefore, we regard this method as a promising choice for the treatment of PLO.

    DOI： 10.1016/j.tjog.2017.10.028

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  • 妊娠27週経腟分娩後に骨盤内膿瘍をきたし腹腔鏡下に処置し得た1例

    有浦 雅代, 齋藤 圭介, 橋本 彩紗, 伊集院 昌郁, 堀田 裕一朗, 古郡 恵, 松永 竜也, 小川 幸, 中村 朋美, 佐藤 美紀子, 宮城 悦子, 榊原 秀也, 平原 史樹

    神奈川産科婦人科学会誌   52 ( 2 )   172 - 175   2016.2

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  • たこつぼ型心筋症により心不全を発症した卵巣腫瘍捻転術後の一例 Reviewed

    伊集院 昌郁, 段 泰行, 浅野 涼子, 飯沼 綾子, 齊藤 真, 北山 玲子, 須郷 慶信, 香川 愛子, 長瀬 寛美, 飛鳥井 邦雄

    関東連合産科婦人科学会誌   52 ( 4 )   585 - 593   2015.11

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  • 子宮頸部嚢胞状腺筋症合併妊娠の一例

    齋藤 圭介, 伊集院 昌郁, 持丸 綾, 田野島 美城, 小川 幸, 平原 史樹

    日本周産期・新生児医学会雑誌   51 ( 2 )   865 - 865   2015.6

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  • 卵巣明細胞癌における妊孕性温存症例2例

    土屋尚輝, 末吉寿実鼓, 戸田美咲, 濱田春, 伊集院昌郁, 宮腰藍衣, 葉山智工, 胡桃坂真由子, 大池有紀, 栃原しおり, 齋藤満里奈, 上野寛枝, 下木原航太, 黒田晋之介, 竹島徹平, 湯村寧, 宮城悦子, 榊原秀也, 村瀬真理子

    日本生殖医学会雑誌   69 ( 4 )   2024

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  • 調節卵巣刺激周期における3D超音波による卵胞計測

    濱田春, 土屋尚輝, 末吉寿実鼓, 戸田美咲, 伊集院昌郁, 宮腰藍衣, 葉山智工, 胡桃坂真由子, 栃原しおり, 齋藤満里奈, 大池有紀, 上野寛枝, 下木原航太, 黒田晋之介, 竹島徹平, 湯村寧, 榊原秀也, 宮城悦子, 村瀬真理子

    日本生殖医学会雑誌   69 ( 4 )   2024

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  • 紡錘体様式は多前核出現率と胚発生に影響する

    上野寛枝, 齋藤満里奈, 栃原しおり, 大池有紀, 胡桃坂真由子, 葉山智工, 宮腰藍衣, 伊集院昌郁, 濱田春, 末吉寿実鼓, 戸田美咲, 土屋尚輝, 湯村寧, 竹島徹平, 黒田晋之介, 宮城悦子, 榊原秀也, 村瀬真理子

    日本生殖医学会雑誌   69 ( 4 )   2024

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  • 胚培養時に精液由来の細菌増殖を認めた一例

    戸田美咲, 末吉寿実鼓, 浜田春, 伊集院昌郁, 宮腰藍衣, 葉山智工, 榊原秀也, 村瀬真理子

    神奈川医学会雑誌   51 ( 2 )   2024

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  • 妊孕性温存目的に子宮内膜癌MPA療法を受けた患者の妊娠転帰と再発頻度

    葉山智工, 土屋尚輝, 末吉寿実鼓, 伊集院昌郁, 葉山智工, 土屋尚輝, 末吉寿実鼓, 伊集院昌郁, 戸田美咲, 濱田春, 胡桃坂真由子, 大池有紀, 栃原しおり, 齋藤満里奈, 上野寛枝, 下木原航太, 黒田晋之介, 竹島徹平, 湯村寧, 宮城悦子, 榊原秀也, 村瀬真理子

    日本生殖医学会雑誌   69 ( 4 )   2024

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  • 非閉塞性無精子症に対する外科的精子採取アプリケーションの開発

    竹島徹平, 齋藤智樹, 苅部樹里衣, 黒田晋之介, 古目谷暢, 栃原しおり, 齋藤満里奈, 上野寛枝, 戸田美咲, 末吉寿実鼓, 濱田春, 伊集院昌郁, 宮腰藍衣, 葉山智工, 村瀬真理子, 湯村寧

    日本生殖医学会雑誌   69 ( 4 )   2024

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  • 培養液中cell-free DNAによる非侵襲的胚ミトコンドリアDNA変異解析

    伊集院昌郁, 末吉寿実鼓, 上野寛枝, 葉山智工, 土屋尚輝, 宮腰藍衣, 戸田美咲, 濱田春, 胡桃坂真由子, 大池有紀, 栃原しおり, 齋藤満里奈, 下木原航太, 黒田晋之介, 竹島徹平, 湯村寧, 宮城悦子, 榊原秀也, 村瀬真理子

    日本生殖医学会雑誌   69 ( 4 )   2024

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  • 当院におけるクラインフェルター症候群のART成績

    戸田美咲, 土屋尚輝, 末吉寿実鼓, 濱田春, 伊集院昌郁, 宮腰藍衣, 葉山智工, 胡桃坂真由子, 大池有紀, 栃原しおり, 齋藤満里奈, 上野寛枝, 下木原航太, 黒田晋之介, 竹島徹平, 湯村寧, 榊原秀也, 宮城悦子, 村瀬真理子

    日本生殖医学会雑誌   69 ( 4 )   2024

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  • 初期胚移植胚選別法mBSの有効性評価

    上野寛枝, 齋藤満里奈, 栃原しおり, 大池有紀, 胡桃坂真由子, 伊集院昌郁, 葉山智工, 濱田春, 宮腰藍衣, 末吉寿実鼓, 戸田美咲, 湯村寧, 竹島徹平, 黒田晋之介, 宮城悦子, 榊原秀也, 村瀬真理子

    日本生殖医学会雑誌   68 ( 4 )   2023

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  • 当院のTESE-ICSIにおけるペントキシフィリン適用の検討

    戸田美咲, 戸田美咲, 戸田美咲, 末吉寿実鼓, 濱田春, 伊集院昌郁, 宮腰藍衣, 葉山智工, 胡桃坂真由子, 大池有紀, 栃原しおり, 齋藤満里奈, 上野寛枝, 竹島徹平, 湯村寧, 榊原秀也, 宮城悦子, 村瀬真理子

    日本生殖医学会雑誌   68 ( 4 )   2023

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  • 当院独自の形態動態学的分類mBSと胚染色異常との関連性

    栃原しおり, 胡桃坂真由子, 大池有紀, 齋藤満里奈, 上野寛枝, 末吉寿実鼓, 伊集院昌郁, 末吉寿実鼓, 伊集院昌郁, 戸田美咲, 濱田春, 宮腰藍衣, 葉山智工, 葉山智工, 竹島徹平, 湯村寧, 宮城悦子, 宮城悦子, 榊原秀也, 村瀬真理子

    日本生殖医学会雑誌   68 ( 4 )   2023

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  • 当院における性腺毒性低-中リスク化学療法後の妊娠転帰

    伊集院昌郁, 末吉寿実鼓, 戸田美咲, 濱田春, 葉山智工, 胡桃坂真由子, 大池有紀, 栃原しおり, 齋藤満里奈, 上野寛枝, 竹島徹平, 湯村寧, 宮城悦子, 村瀬真理子

    日本生殖医学会雑誌   68 ( 4 )   2023

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  • 精巣胚細胞腫瘍患者の治療前凍結精子を用いたICSI妊娠では流産率が高い

    濱田春, 末吉寿実鼓, 戸田美咲, 伊集院昌郁, 宮腰藍衣, 葉山智工, 葉山智工, 胡桃坂真由子, 大池有紀, 栃原しおり, 齋藤満里奈, 上野寛枝, 竹島徹平, 湯村寧, 榊原秀也, 宮城悦子, 村瀬真理子

    日本生殖医学会雑誌   68 ( 4 )   2023

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  • 神奈川県における4次元超音波技術を用いた胎児心臓超音波勉強会

    丸山 大介, 森岡 幹, 山本 賢史, 伊集院 昌郁, 板井 俊幸, 宮城 悦子

    日本産科婦人科学会雑誌   74 ( 臨増 )   S - 590   2022.2

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  • ターナー症候群の免疫異常と不妊・流産の関係

    宮腰藍衣, 葉山智工, 末吉寿実鼓, 末吉寿実鼓, 伊集院昌郁, 伊集院昌郁, 濱田春, 濱田春, 西真裕子, 齋藤満里奈, 栃原しおり, 上野寛枝, 宮城悦子, 榊原秀也, 村瀬真理子

    日本生殖医学会雑誌   67 ( 4 )   2022

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  • 無精子症患者に対してBEP4コース実施後にMD-TESEで精子を回収し生児を得た一例

    末吉寿実鼓, 村瀬真理子, 濱田春, 伊集院昌郁, 宮腰藍衣, 葉山智工, 竹島徹平, 湯村寧

    日本生殖医学会雑誌   67 ( 4 )   2022

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  • ADD-ON EFFECT OF ORAL ANTIOXIDANT THERAPY TO SURGICAL VARICOCELECTOMY ON THE OUTCOME OF ASSISTED REPRODUCTIVE TECHNOLOGY: A SINGLE-CENTER RETROSPECTIVE COHORT STUDY.

    Teppei Takeshima, Shinnosuke Kuroda, Mitsuru Komeya, Marina Saito, Mayuko Nishi, Hiroe Ueno, Mizuki Yamamoto, Akifumi Ijuin, Haru Hamada, Ai Miyakoshi, Tomonari Hayama, Mariko Murase, Yasushi Yumura

    FERTILITY AND STERILITY   116 ( 3 )   E334 - E334   2021.9

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  • HIGH MITOCHONDRIAL DNA REPLICATION IN EMBRYOS DERIVED FROM MYOTONIC DYSTROPHY 1 FEMALE.

    Akifumi Ijuin, Tomonari Hayama, Mizuki Yamamoto, Hiroe Ueno, Haru Hamada, Ai Miyakoshi, Mayuko Nishi, Marina Saito, Shiori Tochihara, Teppei Takeshima, Shinnosuke Kuroda, Hideya Sakakibara, Yasushi Yumura, Etsuko Miyagi, Mariko Murase

    FERTILITY AND STERILITY   116 ( 3 )   E225 - E225   2021.9

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  • 4次元超音波技術を用いた胎児心疾患の双方向性遠隔セミナーに対するアンケート調査

    末光 徳匡, 永昜 洋子, 今泉 翠, 伊集院 昌郁, 小野寺 洋平, 丸山 大介, 門岡 みずほ, 山下 有加, 紀平 力, 川滝 元良

    超音波医学   48 ( Suppl. )   S773 - S773   2021.4

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  • 遠隔ビデオ会議システムとクラウドWEBサービスを用いた胎児心臓超音波勉強会の試み 神奈川県若手産婦人科の会による

    丸山 大介, 森岡 幹, 山本 賢史, 伊集院 昌郁, 末光 徳匡, 板井 俊幸, 山下 有加, 川瀧 元良

    日本遠隔医療学会雑誌   16 ( 補刊号 )   13 - 13   2021.4

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  • 4次元超音波技術を用いた胎児心臓超音波の双方向性遠隔学習セミナーに対するアンケート調査結果の報告

    末光 徳匡, 丸山 大介, 今泉 翠, 伊集院 昌郁, 小野寺 洋平, 永昜 洋子, 門岡 みずほ, 紀平 力, 川瀧 元良

    日本遠隔医療学会雑誌   16 ( 補刊号 )   14 - 14   2021.4

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  • 遠隔ビデオ会議システムとクラウドWEBサービスを用いた胎児心臓超音波勉強会の試み 神奈川県若手産婦人科の会による

    丸山 大介, 森岡 幹, 山本 賢史, 伊集院 昌郁, 末光 徳匡, 板井 俊幸, 山下 有加, 川瀧 元良

    日本遠隔医療学会雑誌   16 ( 補刊号 )   13 - 13   2021.4

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  • 4次元超音波技術を用いた胎児心臓超音波の双方向性遠隔学習セミナーに対するアンケート調査結果の報告

    末光 徳匡, 丸山 大介, 今泉 翠, 伊集院 昌郁, 小野寺 洋平, 永昜 洋子, 門岡 みずほ, 紀平 力, 川瀧 元良

    日本遠隔医療学会雑誌   16 ( 補刊号 )   14 - 14   2021.4

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  • 遠隔ビデオ会議システムとクラウドWEBサービスを用いた胎児心臓超音波勉強会の試み 神奈川県若手産婦人科の会による

    丸山 大介, 森岡 幹, 山本 賢史, 伊集院 昌郁, 末光 徳匡, 板井 俊幸, 山下 有加, 川瀧 元良

    日本遠隔医療学会学術大会プログラム・抄録集   24回   177 - 177   2021.2

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  • 4次元超音波技術を用いた胎児心臓超音波の双方向性遠隔学習セミナーに対するアンケート調査結果の報告

    末光 徳匡, 丸山 大介, 今泉 翠, 伊集院 昌郁, 小野寺 洋平, 永易 洋子, 門岡 みずほ, 紀平 力, 川瀧 元良

    日本遠隔医療学会学術大会プログラム・抄録集   24回   177 - 177   2021.2

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  • SURVEY ON PERCEPTION OF GERMLINE GENE THERAPY AMONG JAPANESE MEDICAL STUDENT.

    Tomonari Hayama, Akifumi Ijuin, Ai Miyakoshi, Haru Hamada, Mitsuru Komeya, Teppei Takeshima, Shinnosuke Kuroda, Yasushi Yumura, Mariko Murase, Etsuko Miyagi, Hideya Sakakibara

    FERTILITY AND STERILITY   114 ( 3 )   E198 - E198   2020.9

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  • 進行卵巣癌の治療選択に子宮内膜細胞診が果たす役割について考える

    佐治 晴哉, 伊集院 昌郁, 能勢 英理子, 松倉 圭太, 荒井 博, 田尻 亮輔, 権藤 俊一

    日本臨床細胞学会雑誌   56 ( Suppl.1 )   370 - 370   2017.4

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  • 子宮内膜細胞診疑陽性を呈し術前に原発巣の同定に難渋した子宮体癌の1例 Reviewed

    伊集院 昌郁, 権藤 俊一, 荒井 博, 松倉 圭太, 能勢 英理子, 佐治 晴哉

    神奈川県臨床細胞学会誌   21 ( 1 )   45 - 49   2016.8

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    Authorship：Lead author   Language：Japanese   Publishing type：Article, review, commentary, editorial, etc. (scientific journal)   Publisher：神奈川県臨床細胞学会  

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Awards

  • JSOG Congress Encouragement Award

    2023.4   Mitochondrial DNA mutations can influence the post-implantation chromosomal purification and development in human embryos.

    Akifumi Ijuin, Tomonari Hayama, Ai Miyakoshi, Haru Hamada, Sumiko Sueyoshi, Haruka Hamanoue, Etsuko Miyagi, Hiroki Kurahashi, Hideya Sakakibara, Mariko Murase

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Research Projects

  • Non-invasive analysis of mitochondrial DNA from spent medium.

    Grant number：24K19727  2024.4 - 2027.3

    Japan Society for the Promotion of Science  Grants-in-Aid for Scientific Research  Grant-in-Aid for Early-Career Scientists

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    Grant amount：\4550000 （ Direct Cost: \3500000 、 Indirect Cost：\1050000 ）

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