2025/06/01 更新

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写真a

ヒガシヒラ ショウタ
東平 翔太
Shota Higashihira
所属
附属市民総合医療センター 整形外科 助教
職名
助教
外部リンク

学位

  • 医学博士 ( 横浜市立大学 )

研究キーワード

  • ディープラーニング

  • バイオフィルム感染

  • 股関節鏡視下手術

  • 人工関節周囲感染

  • コンピューターシミュレーション

  • 動態解析

  • PAMPs/DAMPs

  • Femoroacetabular impingement

  • 歯周病

  • AI

研究分野

  • ライフサイエンス / 整形外科学

  • ライフサイエンス / 細胞生物学

  • ライフサイエンス / 病態系口腔科学

経歴

  • 横浜市立大学附属市民総合医療センター   整形外科   助教

    2023年 - 現在

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  • 米国インディアナ大学医学部   整形外科   Postdoctoral Fellow

    2020年 - 2023年

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  • 横浜掖済会病院   整形外科   医員

    2019年 - 2020年

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  • 横浜市立大学附属病院   整形外科   医員

    2017年 - 2019年

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所属学協会

論文

  • Biofilm Formation is Durably Prevented on Pre-Fabricated Antibiotic Cement Spacers Compared to Cobalt Chrome and Polyethylene

    Shota Higashihira, Stefanie J. Simpson, Christopher J. Arnold, Evan R. Deckard, Robert Meneghini, Edward M. Greenfield, Leonard Buller

    The Journal of Arthroplasty   2025年3月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)  

    DOI: 10.1016/j.arth.2024.08.046

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  • Computer-Assisted Hip Arthroscopic Surgery for Secondary Femoroacetabular Impingement After Rotational Acetabular Osteotomy Using Capsular Takedown Techniques

    Shota Higashihira, Yohei Yukizawa, Ayahiro Kadowaki, Shu Takagawa, Hyonmin Choe, Yutaka Inaba, Naomi Kobayashi

    Arthroscopy Techniques   2025年2月

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    掲載種別:研究論文(学術雑誌)  

    DOI: 10.1016/j.eats.2024.103193

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  • Meniscus Reconstruction Using Autologous Tendon Combined With Open-Wedge High Tibial Osteotomy: A Technique to Achieve Rigid Fixation and Avoid Interference Between Locking Screws and Tibial Bone Tunnel

    Shu Takagawa, Ryohei Takeuchi, Naomi Kobayashi, Yohei Yukizawa, Kunihito Hirotomi, Shota Higashihira, Yutaka Inaba

    Arthroscopy Techniques   2024年10月

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    掲載種別:研究論文(学術雑誌)  

    DOI: 10.1016/j.eats.2024.103064

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  • Cam type FAIにおいて骨盤後傾が可動域改善に著効しないリスク因子は何か? コンピュータシミュレーション解析と臨床成績による検討

    齊藤 昌愛, 小林 直実, 本田 秀樹, 加茂野 絵美, 東平 翔太, 雪澤 洋平, 稲葉 裕

    Hip Joint   50 ( 2 )   12 - 12   2024年8月

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    記述言語:日本語   出版者・発行元:日本股関節学会  

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  • 人工関節周囲感染(PJI)の予防・診断・治療の今後の動向 PJI診断の問題点 迅速遺伝子検査のより広い普及と日常臨床使用へ向けてのステップ

    小林 直実, 崔 賢民, 東平 翔太, 加茂野 絵美, 稲葉 裕

    日本骨・関節感染症学会プログラム・抄録集   47回   55 - 55   2024年7月

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    記述言語:日本語   出版者・発行元:(一社)日本骨・関節感染症学会  

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  • Comparison of the indications for high tibial osteotomy and double-level osteotomy for the correction of diverse lower-leg deformities in an Asian population with medial compartment osteoarthritis: a retrospective observational study

    Shu Takagawa, Yohei Yukizawa, Kunihito Hirotomi, Shota Hiagashihra, Yutaka Inaba, Naomi Kobayashi

    International Orthopaedics   2024年5月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)  

    DOI: 10.1007/s00264-024-06218-0

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  • Hybrid Closed Wedge High Tibial Osteotomy Maintains the Leg Length After Surgery Compared With Open Wedge High Tibial Osteotomy

    Shu Takagawa, Naomi Kobayashi, Yohei Yukizawa, Kunihito Hirotomi, Shota Higashihira, Yutaka Inaba

    Cureus   2024年4月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)  

    DOI: 10.7759/cureus.57953

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  • Evaluation of the Postoperative Risk of Deep Tissue Injury to the Lower Extremities Following Surgery in the Lithotomy Position. 国際誌

    Yohei Yukizawa, Emi Kamono, Shu Takagawa, Kunihito Hirotomi, Shota Higashihira, Hyonmin Choe, Yutaka Inaba, Naomi Kobayashi

    Cureus   16 ( 4 )   e57413   2024年4月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)  

    Background The aim of this study was to determine the incidence of deep tissue injury (DTI) and potential risk factors after surgery in the lithotomy position. Methods All patients who underwent surgery in the lithotomy position under general anesthesia at a single center between January 2017 and December 2021 were retrospectively evaluated. The medical records of these patients were reviewed, and patient demographic and clinical characteristics, surgical data, and occurrence of DTI were recorded. Results During the study period, 5146 patients, 2055 (39.9%) males and 3091 (60.1%) females, with a mean age of 57.3 ± 17.4 years, underwent surgery in the lithotomy position. Seven (0.14%) patients developed DTI on their calf following surgery. All presented with severe pain and swelling, requiring prolonged hospital stay. Multivariate analysis showed that male sex (odds ratio (OR): 11.43; 95% confidence interval (CI): 1.15-113.34, p = 0.037), higher BMI (OR: 1.32; 95% CI: 1.17-1.50, p = 0.0001), and longer operation time (OR: 1.01; 95% CI: 1.004-1.014, p = 0.0002) were independent risk factors for postoperative DTI. Optimal cut-off values for BMI and operation time were 23.5 kg/m2 (sensitivity = 100%; specificity = 64%) and 285 minutes (sensitivity = 100%; specificity = 90%), respectively. Conclusion Factors significantly associated with DTI include male sex, higher BMI, and prolonged operation time.

    DOI: 10.7759/cureus.57413

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  • Halicin remains active against Staphylococcus aureus in biofilms grown on orthopaedically relevant substrates

    Shota Higashihira, Stefanie J. Simpson, Akira Morita, Joash R. Suryavanshi, Christopher J. Arnold, Roman M. Natoli, Edward M. Greenfield

    Bone & Joint Research   2024年3月

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    掲載種別:研究論文(学術雑誌)  

    DOI: 10.1302/2046-3758.133.BJR-2023-0038.R2

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  • 股関節鏡視下手術の適応と限界 股関節鏡手術におけるコンピュータ支援技術の役割と限界

    小林 直実, 雪澤 洋平, 東平 翔太, 齊藤 昌愛, 稲葉 裕

    日本整形外科学会雑誌   98 ( 2 )   S511 - S511   2024年3月

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    記述言語:日本語   出版者・発行元:(公社)日本整形外科学会  

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  • 股関節鏡視下手術の適応と限界 股関節鏡手術におけるコンピュータ支援技術の役割と限界

    小林 直実, 雪澤 洋平, 東平 翔太, 齊藤 昌愛, 稲葉 裕

    日本整形外科学会雑誌   98 ( 2 )   S511 - S511   2024年3月

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    記述言語:日本語   出版者・発行元:(公社)日本整形外科学会  

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  • 超高齢社会における人工関節長期成績向上のためにできること THA術後インプラント周囲骨密度低下に対する薬物介入 ネットワークメタ解析による検討を中心に

    小林 直実, 森田 彰, 加茂野 絵美, 大山 格, 雪澤 洋平, 東平 翔太, 崔 賢民, 稲葉 裕

    日本整形外科学会雑誌   98 ( 2 )   S89 - S89   2024年3月

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    記述言語:日本語   出版者・発行元:(公社)日本整形外科学会  

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  • A Comparison of the Minimum Inhibitory Concentration of Antibiotics in Staphylococcus Species Isolated From Orthopedic and Respiratory Medicine Infections. 国際誌

    Akito Tomoyama, Naomi Kobayashi, Hyonmin Choe, Hiroyuki Ike, Yohei Yukizawa, Shota Higashihira, Shu Takagawa, Ken Kumagai, Yutaka Inaba

    Cureus   15 ( 11 )   e49535   2023年11月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)  

    INTRODUCTION: Antibiotic susceptibility is very important for the successful treatment of orthopedic infections, particularly for implant-related infections. While the minimum inhibitory concentrations (MICs) of Staphylococcus species were well investigated for the isolates from the respiratory tract, investigations for orthopedic pathogens are very limited. We investigated the antibiotic MIC values of Staphylococcus species isolated from orthopedic infections and compared them with those of respiratory medicine isolates used as a control. METHODS: The MICs of vancomycin (VCM), arbekacin (ABK), teicoplanin (TEIC), linezolid (LZD), and rifampicin (RFP) of a total of consecutive 259 (89 orthopedic and 170 respiratory) Staphylococcus speciesisolated in our laboratory from January 2013 to July 2016 were retrospectively reviewed. Differences between the MICs of each antibiotic in orthopedic and respiratory samples were determined. RESULTS: The number of methicillin-sensitive Staphylococcus aureus (MSSA) with a VCM MIC of <0.5 μg/mL among respiratory isolates was significantly higher than that among orthopedic isolates, while those with a MIC of 2 μg/mL were significantly lower (P = 0.0078). The proportion of methicillin-resistant coagulase-negative staphylococci (MRCNS) isolates with a VCM MIC of 2 μg/mL was significantly higher in orthopedic samples than that of methicillin-resistant Staphylococcus aureus (MRSA) (P < 0.001) in respiratory isolates. The proportion of MRCNS orthopedic isolates with an RFP MIC of >2 μg/mL was significantly higher (P = 0.0058) than that of other orthopedic staphylococci. CONCLUSIONS: The VCM MICs of Staphylococcus species from orthopedic infections were higher than those of respiratory samples, particularly MRCNS from implant-related samples.

    DOI: 10.7759/cureus.49535

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  • CORR Insights®: Allograft or Synthetic Mesh Extensor Mechanism Reconstruction After TKA Carries a High Risk of Infection, Revision, and Extensor Lag. 国際誌

    Shota Higashihira

    Clinical orthopaedics and related research   2023年10月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)  

    DOI: 10.1097/CORR.0000000000002879

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  • 特集 股関節鏡手術のエビデンス-治療成績の現状 股関節鏡手術の術前計画とコンピュータ支援技術

    小林 直実, 本田 秀樹, 雪澤 洋平, 東平 翔太, 加茂野 絵美

    臨床整形外科   58 ( 7 )   891 - 898   2023年7月

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    出版者・発行元:株式会社医学書院  

    DOI: 10.11477/mf.1408202727

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  • 【股関節鏡手術のエビデンス-治療成績の現状】股関節鏡手術の術前計画とコンピュータ支援技術

    小林 直実, 本田 秀樹, 雪澤 洋平, 東平 翔太, 加茂野 絵美

    臨床整形外科   58 ( 7 )   891 - 898   2023年7月

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    記述言語:日本語   出版者・発行元:(株)医学書院  

    <文献概要>股関節鏡手術,特にFAIに対する骨軟骨形成を中心にコンピュータシミュレーションを用いた術前計画と,計画を可能な限り正確に遂行するためのコンピュータナビゲーション支援手術の実際について詳述する.ナビゲーション支援下cam切除の精度評価,骨盤動態のコンピュータシミュレーション解析研究の結果も紹介する.

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    その他リンク: https://search.jamas.or.jp/default/link?pub_year=2023&ichushi_jid=J01554&link_issn=&doc_id=20230706040011&doc_link_id=10.11477%2Fmf.1408202727&url=https%3A%2F%2Fdoi.org%2F10.11477%2Fmf.1408202727&type=%E5%8C%BB%E6%9B%B8.jp_%E3%82%AA%E3%83%BC%E3%83%AB%E3%82%A2%E3%82%AF%E3%82%BB%E3%82%B9&icon=https%3A%2F%2Fjk04.jamas.or.jp%2Ficon%2F00024_2.gif

  • Effect of 3-Dimensional Versus Single-Plane Changes in Pelvic Dynamics on Range of Motion in Hips With Femoroacetabular Impingement: A Computer Simulation Analysis 国際誌

    Hideki Honda, Naomi Kobayashi, Emi Kamono, Yohei Yukizawa, Shota Higashihira, Shu Takagawa, Hyonmin Choe, Hiroyuki Ike, Taro Tezuka, Yutaka Inaba

    ORTHOPAEDIC JOURNAL OF SPORTS MEDICINE   10 ( 9 )   23259671221123604 - 23259671221123604   2022年9月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)   出版者・発行元:SAGE PUBLICATIONS INC  

    Background: Femoroacetabular impingement (FAI) is primarily caused by bony impingement between the acetabulum and femoral neck during hip motion. Increasing posterior pelvic tilt improves hip range of motion in patients with FAI. Purpose: To use computer simulation analysis to compare the effects of 3-dimensional (3D) changes in pelvic tilt (sagittal tilt [St], axial rotation, and coronal tilt) with changes in a single plane (St), with the aim of improving range of motion in patients with FAI. Study Design: Controlled laboratory study. Methods: We evaluated 43 patients with FAI treated by arthroscopic cam resection. A 3D simulation was used to construct the following pelvic models: a 5 degrees and 10 degrees increase posteriorly in St (St5 degrees and St10 degrees) and a combined 5 degrees change in St, axial rotation, and coronal tilt (Complex5 degrees) from the baseline of the anterior pelvic plane. Improvements in maximum internal rotation (MIR) at 45 degrees, 70 degrees, and 90 degrees of hip flexion and improvements in maximum flexion with no internal rotation were compared among the St5 degrees, St10 degrees, and Complex5 degrees models. The pelvic models of each single-plane change of 5 degrees and 10 degrees were evaluated in the same simulation. Results: At 90 degrees and 70 degrees, there was a significant difference between the Complex5 degrees and St10 degrees models with respect to improvement in MIR (P = .004 at 90 degrees of flexion; P = .017 at 70 degrees of flexion). There was no significant difference in MIR at 45 degrees of flexion (P = .71) or in maximum flexion (P = .42). Conclusion: At 70 degrees and 90 degrees of hip flexion, a combined change in 3D pelvic alignment of 5 degrees (ie, St, axial rotation, and coronal tilt) was more effective in improving hip MIR than a 10 degrees change in St only.

    DOI: 10.1177/23259671221123604

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  • Halicin Is Effective Against Staphylococcus aureus Biofilms In Vitro 国際誌

    Shota Higashihira, Stefanie Jan Simpson, Christopher David Collier, Roman Michael Natoli, Mizuho Kittaka, Edward Michael Greenfield

    CLINICAL ORTHOPAEDICS AND RELATED RESEARCH   480 ( 8 )   1476 - 1487   2022年8月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)   出版者・発行元:LIPPINCOTT WILLIAMS & WILKINS  

    Background Biofilms protect bacteria from the host immune system and many antibiotics, making the treatment of orthopaedic infections difficult. Halicin, a recently discovered antibiotic, has potent activity against nonorthopaedic infections in mice and the planktonic, free-living forms of many bacterial species, including Staphylococcus aureus, a common cause of orthopaedic infections. Importantly, halicin did not induce resistance in vitro and was effective against drug-resistant bacteria and proliferating and quiescent bacteria. Quiescence is an important cause of antibiotic tolerance in biofilms. However, whether halicin acts on biofilms has not been tested. Questions/purposes (1) Does halicin reduce the viability of S. aureus in less mature and more mature biofilms as it does in planktonic cultures? (2) How do the relative effects of halicin on S. aureus biofilms and planktonic cultures compare with those of conventional antibiotics (tobramycin, cefazolin, vancomycin, or rifampicin) that are commonly used in clinical orthopaedic infections? Methods To measure minimal biofilm eradication concentrations (MBECs) with less mature 3-day and more mature 7-day biofilms, we used 96-well peg plates that provided high throughput and excellent reproducibility. After S. aureus-Xen36 biofilm formation, planktonic bacteria were removed from the cultures, and the biofilms were exposed to various concentrations of halicin, tobramycin, cefazolin, vancomycin, or rifampicin for 20 hours. Biofilm viability was determined by measuring resazurin reduction or by counting colony-forming units after sonication. To determine effects of halicin and the conventional antibiotics on biofilm viability, we defined MBEC75 as the lowest concentration that decreased viability by 75% or more. To determine effects on bacterial viability in planktonic cultures, minimum inhibitory concentrations (MICs) were determined with the broth dilution method. Each result was measured in four to 10 independent experiments. Results We found no differences between halicin's effectiveness against planktonic S. aureus and 3-day biofilms (MIC and MBEC75 for 3-day biofilms was 25 mu M [interquartile range 25 to 25 and 25 to 25, respectively]; p > 0.99). Halicin was eightfold less effective against more mature 7-day biofilms (MBEC75 = 200 mu M [100 to 200]; p < 0.001). Similarly, tobramycin was equally effective against planktonic culture and 3-day biofilms (MIC and MBEC75 for 3-day biofilms was 20 mu M [20 to 20 and 10 to 20, respectively]; p > 0.99). Tobramycin's MBEC75 against more mature 7-day biofilms was 320 mu M (320 to 480), which is 16-fold greater than its planktonic MIC (p = 0.03). In contrast, the MBEC75 for cefazolin, vancomycin, and rifampicin against more mature 7-day biofilms were more than 1000-fold (> 1000; p < 0.001), 500-fold (500 to 875; p < 0.001), and 3125-fold (3125 to 5469; p = 0.004) greater than their planktonic MICs, respectively, consistent with those antibiotics' relative inactivity against biofilms. Conclusion Halicin was as effective against S. aureus in less mature 3-day biofilms as those in planktonic cultures, but eightfold higher concentrations were needed for more mature 7-day biofilms. Tobramycin, an antibiotic whose effectiveness depends on biofilm maturity, was also as effective against S. aureus in less mature 3-day biofilms as those in planktonic cultures, but 16-fold higher concentrations were needed for more mature 7-day biofilms.In contrast, cefazolin, vancomycin, and rifampicin were substantially less active against both less and more mature biofilms than against planktonic cultures.

    DOI: 10.1097/CORR.0000000000002251

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  • Accuracy of Computer Navigation-Assisted Arthroscopic Osteochondroplasty for Cam-Type Femoroacetabular Impingement Using the Model-to-Image Registration Method 国際誌

    Koki Abe, Masatoshi Oba, Naomi Kobayashi, Shota Higashihira, Hyonmin Choe, Taro Tezuka, Hiroyuki Ike, Yutaka Inaba

    AMERICAN JOURNAL OF SPORTS MEDICINE   50 ( 5 )   1272 - 1280   2022年4月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)   出版者・発行元:SAGE PUBLICATIONS INC  

    Background: Precise osteochondroplasty is important in arthroscopic hip surgery for cam-type femoroacetabular impingement (FAI). Although computer-assisted surgery with a navigation system may enhance the accuracy of arthroscopic osteochondroplasty, few clinical studies have assessed its accuracy. Purpose: To evaluate the accuracy of arthroscopic osteochondroplasty by a computed tomography (CT)-based navigation system for cam-type FAI, using 3-dimensional (3D) reconstruction with more detail compared with previous methods. Study design: Case series; Level of evidence, 4. Methods: Twenty patients (14 men and 6 women) who underwent navigation-assisted arthroscopic surgery for cam-type FAI were included. The preoperative 3D model of the femur was constructed from each patient's CT data, and a planned model with virtual cam resection was generated. A femoral model was reconstructed from CT data postoperatively. The 3 models for each patient were overlaid using a 3D model registration method. Then, the contours of the bone resection area of each model were compared by measuring them. To measure the deviation between planned and actual bone resections, 4 cross-sectional images of the 3 femoral models were set at one-quarter intervals from the femoral head radius. All measurements were based on clockface lines set around the femoral neck axis at 30-minute intervals. Differences between the planned and postoperative contour lines were deemed resection deviations. Results: All cam resections were performed in the anterior half of the region of interest. Therefore, only the anterior half (48 points) of the 96 points per case were analyzed. In 876 (91.3%) points of the total measurement points (960 points/20 cases), the error in resection depth was within 3 mm. Overresection was observed at 35 (3.6%) points and underresection at 49 (5.1%) points. The observed maximum deviations from the planned models were 6.3 mm overresection and -7.1 mm underresection. The alpha angles of the postoperative model at the posterior 9- to 3-o'clock position were Conclusion: Navigation-assisted arthroscopic osteochondroplasty showed favorable accuracy. Underresection was more frequent than overresection on the anterosuperior side of the femur, despite assistance of the navigation system.

    DOI: 10.1177/03635465221074338

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  • Patient-reported outcome measures after total knee arthroplasty using knee injury and osteoarthritis outcome score

    Shota Higashihira, Riki Inasaka, Yuichi Iwamura, Motonori Kohno, Gosuke Akiyama, Yutaka Inaba

    Journal of Research and Practice on the Musculoskeletal System   05 ( 03 )   93 - 100   2021年9月

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    掲載種別:研究論文(学術雑誌)   出版者・発行元:Hylonome Publications  

    DOI: 10.22540/jrpms-05-093

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  • Dorr type別におけるZweymuller type stemとtaper wedge type stemの人工股関節周囲骨密度変化の比較

    森田 彰, 小林 直実, 崔 賢民, 手塚 太郎, 池 裕之, 大庭 真俊, 東平 翔太, 安部 晃生, 稲葉 裕

    日本整形外科学会雑誌   95 ( 8 )   S1663 - S1663   2021年8月

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    記述言語:日本語   出版者・発行元:(公社)日本整形外科学会  

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  • Effect of Decreasing the Anterior Pelvic Tilt on Range of Motion in Femoroacetabular Impingement: A Computer-Simulation Study 国際誌

    Naomi Kobayashi, Shota Higashihira, Haruna Kitayama, Emi Kamono, Yohei Yukizawa, Takayuki Oishi, Shu Takagawa, Hideki Honda, Hyonmin Choe, Yutaka Inaba

    ORTHOPAEDIC JOURNAL OF SPORTS MEDICINE   9 ( 4 )   2325967121999464 - 2325967121999464   2021年4月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)   出版者・発行元:SAGE PUBLICATIONS INC  

    Background:The influence of pelvic tilt mobility, which can be reproduced in computer-simulation models, is an important subject to be addressed in the understanding of femoroacetabular impingement (FAI) pathophysiology.Purpose:To use computer-simulation models of FAI cases to evaluate the optimum improvement in hip range of motion (ROM) achieved by decreasing the anterior pelvic tilt and compare the results with the improvement in ROM achieved after cam resection surgery.Study Design:Controlled laboratory study.Methods:The pre- and postoperative computed tomography (CT) images from 28 patients with FAI treated with arthroscopic cam resection were evaluated. Using a dynamic computer-simulation program, 3-dimensional models with a 5 degrees and a 10 degrees decrease in anterior pelvic tilt from the supine functional pelvic plane (baseline) were created from the preoperative CT scans. Similar models were constructed for hips before (at baseline) and after cam resection. Improvements from baseline in maximum internal rotation at 45 degrees, 70 degrees, and 90 degrees of flexion were assessed for the 5 degrees change in pelvic tilt, 10 degrees change in pelvic tilt, and cam resection models, and the results were compared for all conditions.Results:The combination of a 10 degrees change in pelvic tilt and cam resection showed the largest ROM improvement from baseline (P < .001). Improvement in internal rotation in the cam resection model was significantly higher compared with the 5 degrees pelvic tilt change model (P < .001), while there was no significant difference between the cam resection model and the 10 degrees pelvic tilt change model.Conclusion:Decreasing anterior pelvic tilt by 10 degrees in the preoperative computer simulation model resulted in an equivalent effect to cam resection, while a 5 degrees change in pelvic tilt was inferior to cam resection in terms of ROM improvement.

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  • Preoperative factors predicting the severity of BMD loss around the implant after Total hip Arthroplasty 国際誌

    Akira Morita, Naomi Kobayashi, Hyonmin Choe, Taro Tezuka, Shota Higashihira, Yutaka Inaba

    BMC MUSCULOSKELETAL DISORDERS   22 ( 1 )   290 - 290   2021年3月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)   出版者・発行元:BMC  

    Background Stress shielding after total hip arthroplasty (THA) leads to loss of bone mineral density (BMD) around the femoral implants, particularly in the proximal area. Loss of BMD around the implant is likely to occur within 1 year after THA; however, its severity depends on patient characteristics. This study evaluated preoperative factors correlated with the severity of zone 7 BMD loss after THA. Methods This retrospective cohort study included 48 patients who underwent primary THA from October 2011 to December 2015. All patients underwent implantation of a Zweymuller-type femoral component without any postoperative osteoporosis medications. The objective variable was a change in zone 7 BMD after 1 year. Factors evaluated included age, body mass index, Japanese Orthopaedic Association score, Harris Hip Score, Canal Flare Index (CFI), and lumbar BMD on the frontal and lateral sides. Univariate and multivariate regression analyses identified factors correlated with loss of zone 7 BMD. Results Univariate regression analysis identified CFI (P = 0.003) and preoperative lumbar BMD on the anterior-posterior (P = 0.003) and lateral (P < 0.001) sides as being correlated with loss of zone 7 BMD. Multivariate regression analysis identified CFI (P = 0.014) and lumbar BMD on the lateral side (P < 0.001) as being correlated independently with loss of zone 7 BMD. Conclusion Lower preoperative lumbar BMD on the lateral side and lower CFI were correlated with zone 7 BMD loss after THA. Patients with these characteristics should be monitored carefully for severe BMD loss after THA.

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  • A rare case of osteoblastoma in the femoral head combined with cam-type femoroacetabular impingement: A case report 国際誌

    Akira Morita, Naomi Kobayashi, Hyonmin Choe, Taro Tezuka, Yusuke Kawabata, Kenta Hayashida, Shota Higashihira, Ikuma Kato, Yutaka Inaba

    SAGE OPEN MEDICAL CASE REPORTS   8   2050313X20978022   2020年12月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)   出版者・発行元:SAGE PUBLICATIONS INC  

    Osteoblastoma is a relatively rare benign bone-forming tumor accounting for less than 1% of all bone tumors. This report describes a patient with an osteoblastoma in the femoral head complicated by coexistence of femoroacetabular impingement. A 25-year-old male rugby football player complained of severe right hip pain after an injury during rugby practice. The pain became progressively worse despite resting from sports activity and rehabilitation for 4 months. The image inspection revealed bone tumor complicated by cam-type femoroacetabular impingement and a labral injury. Hip arthroscopic surgery was planned using a navigation system and a three-dimensional model for both complete debridement and cam resection. The tumor was resected by open surgery using a posterior approach. The bone tumor was diagnosed histopathologically as an osteoblastoma. The patient's symptoms improved markedly after surgery, with no evidence of local tumor recurrence or hip arthritis 1 year later.

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  • Use of a 3D Virtually Reconstructed Patient-Specific Model to Examine the Effect of Acetabular Labral Interference on Hip Range of Motion 国際誌

    Shota Higashihira, Naomi Kobayashi, Hyonmin Choe, Kosuke Sumi, Yutaka Inaba

    ORTHOPAEDIC JOURNAL OF SPORTS MEDICINE   8 ( 11 )   2325967120964465 - 2325967120964465   2020年11月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)   出版者・発行元:SAGE PUBLICATIONS INC  

    Background:The labrum is likely to influence impingement, which may also depend on acetabular coverage. Simulating impingement using 3-dimensional (3D) computed tomography (CT) is a potential solution to evaluating range of motion (ROM); however, it is based on bony structures rather than on soft tissue.Purpose:To examine ROM when the labrum is considered in a 3D dynamic simulation. A particular focus was evaluation of maximum flexion and internal rotation angles before occurrence of impingement, comparing them in cases of cam-type femoroacetabular impingement (FAI) and borderline developmental dysplasia of the hip (BDDH).Study Design:Descriptive laboratory study.Methods:Magnetic resonance imaging (MRI) and CT scans of 40 hips (20 with cam-type FAI and 20 with BDDH) were reviewed retrospectively. The thickness and width of the labrum were measured on MRI scans. A virtual labrum was reconstructed based on patient-specific sizes measured on MRI scans. The impingement point was identified using 3D dynamic simulation and was compared with the internal rotation angle before and after labral reconstruction.Results:The thickness and width of the labrum were significantly larger in BDDH than in FAI (P < .001). In FAI, the maximum internal rotation angles without the labrum were 30.3 degrees at 90 degrees of flexion and 56.9 degrees at 45 degrees of flexion, with these values decreasing to 18.7 degrees and 41.4 degrees, respectively, after labral reconstruction (P < .001). In BDDH, the maximum internal rotation angles were 48.0 degrees at 90 degrees of flexion and 76.7 degrees at 45 degrees of flexion without the labrum, decreasing to 31.1 degrees and 55.3 degrees, respectively, after labral reconstruction (P < .001). The differences in the angles before and after labral reconstruction were larger in BDDH than in FAI (90 degrees of flexion, P = .03; 45 degrees of flexion, P = .01).Conclusion:As the labrum was significantly more hypertrophic in BDDH than in FAI, the virtual labral model revealed that the labrum's interference with the maximum internal rotation angle was also significantly larger in BDDH.

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  • 人工股関節全置換術患者におけるステム周囲の術後骨密度低下に関連する術前因子の検討

    森田 彰, 小林 直実, 崔 賢民, 手塚 太郎, 大庭 真俊, 宮前 祐之, 東平 翔太, 安部 晃生, 稲葉 裕

    日本整形外科学会雑誌   94 ( 8 )   S1890 - S1890   2020年9月

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    記述言語:日本語   出版者・発行元:(公社)日本整形外科学会  

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  • The Practice of Computer-Assisted Planning and Navigation for Hip Arthroscopy

    Naomi Kobayashi, Shota Higashihira, Yutaka Inaba

    Essentials in Hip and Ankle   2020年7月

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    掲載種別:研究論文(学術雑誌)   出版者・発行元:{IntechOpen}  

    DOI: 10.5772/intechopen.89502

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  • Correlations and Reproducibility Between Radiographic and Radial Alpha Angles in the Evaluation of Cam Morphology 国際誌

    Naomi Kobayashi, Kosuke Sumi, Shota Higashihira, Hyonmin Choe, Taro Tezuka, Takayuki Oishi, Yohei Yukizawa, Akira Morita, Yutaka Inaba

    ORTHOPAEDIC JOURNAL OF SPORTS MEDICINE   8 ( 7 )   2325967120932922 - 2325967120932922   2020年7月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)   出版者・発行元:SAGE PUBLICATIONS INC  

    Background: The alpha angle used to evaluate cam morphology can be determined on different imaging views; however, 2-dimensional (2D) imaging can present limitations in terms of the reproducibility of the radial alpha angle. Recent developments in 3-dimensional (3D) high-resolution magnetic resonance imaging (MRI) have allowed detailed evaluations of the radial alpha angle. Purpose: To determine whether there are any correlations or discrepancies between the 2D alpha angle on plain radiography and the maximum radial alpha angle on 3D MRI. Study Design: Cohort study (diagnosis); Level of evidence, 2. Methods: A total of 42 hips from 39 patients (19 males, 20 females) were analyzed, including 22 hips with femoroacetabular impingement (FAI; mean age, 41 years) and 20 hips with borderline developmental dysplasia of the hip (BDDH; mean age, 43 years). Radial images were reconstructed from 3D multiple echo recombined gradient echo (MERGE) MRI. Differences in the maximum radial alpha angle on MRI between hips with FAI and BDDH were evaluated. Correlations and discrepancies between the maximum radial alpha angle on MRI and alpha angles on the anteroposterior, cross-table lateral, and 45 degrees Dunn views of radiography were also evaluated. Results: The maximum radial alpha angle was significantly higher for hips with FAI than for hips with BDDH. On average, the greatest alpha angle on radial MRI was higher than the alpha angle on each of the 3 radiographic views for both FAI and BDDH. The 45 degrees Dunn view revealed the smallest discrepancy for both FAI (P= .005) and BDDH (P= .002). The cross-table lateral view had the highest correlation with the maximum radial alpha angle for BDDH (P< .001). Conclusion: We reconfirmed the utility of the 45 degrees Dunn view, with it presenting the best reproducibility for the maximum radial alpha angle in the evaluation of cam morphology, while the cross-table lateral view revealed the best correlation with the maximum radial alpha angle, particularly for hips with BDDH.

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  • Influence of comorbid knee osteoarthritis on surgical outcome and sagittal spinopelvic/lower-extremity alignment in elderly patients with degenerative lumbar spondylolisthesis undergoing transforaminal lumbar interbody fusion 国際誌

    Motonori Kohno, Yuichi Iwamura, Riki Inasaka, Gosuke Akiyama, Shota Higashihira, Takuya Kawai, Takanori Niimura, Yutaka Inaba

    JOURNAL OF NEUROSURGERY-SPINE   32 ( 6 )   850 - 858   2020年6月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)   出版者・発行元:AMER ASSOC NEUROLOGICAL SURGEONS  

    OBJECTIVE This retrospective study aimed to clarify the influence of comorbid severe knee osteoarthritis (KOA) on surgical outcome in terms of sagittal spinopelvic/lower-extremity alignment in elderly patients with degenerative lumbar spondylolisthesis (DLS).METHODS In total, 110 patients aged at least 65 years (27 men, 83 women; mean age 74.0 years) who underwent short-segment lumbar fusion were included in the present study. Using the Kellgren-Lawrence (KL) grading system, patients were categorized into those with no to mild KOA (the mild-OA group: KL grades 0-2), moderate KOA (moderate-OA group: KL grade 3), or severe KOA (severe-OA group: KL grade 4). Surgical results were assessed using the Japanese Orthopaedic Association (JOA) scoring system, and spinopelvic/lower-extremity parameters were compared among the 3 groups. Adjacent-segment disease (ASD) was assessed over a mean follow-up period of 4.7 years (range 2-8.1 years).RESULTS The study cohort was split into the mild-OA group (42 patients), the moderate-OA group (28 patients), and the severe-OA group (40 patients). The severe-OA group contained significantly more women (p = 0.037) and patients with double-level listhesis (p = 0.012) compared with the other groups. No significant differences were found in mean postoperative JOA scores or recovery rate among the 3 groups. The mean postoperative JOA subscore for restriction of activities of daily living was only significantly lower in the severe-OA group compared with the other groups (p = 0.010). The severe-OA group exhibited significantly greater pelvic incidence, pelvic tilt, and knee flexion angle (KFA), along with a smaller degree of lumbar lordosis than the mild-OA group both pre- and postoperatively (all p < 0.05). Overall, the rate of radiographic ASD was observed to be higher in the severe-OA group than in the mild-OA group (p = 0.015). Patients with ASD in the severe-OA group exhibited significantly greater pelvic tilt, pre- and postoperatively, along with less lumbar lordosis, than the patients without ASD postoperatively (all p < 0.05).CONCLUSIONS A lack of lumbar lordosis caused by double-level listhesis and knee flexion contracture compensated for by far greater pelvic retroversion is experienced by elderly patients with DLS and severe KOA. Therefore, corrective lumbar surgery and knee arthroplasty may be considered to improve sagittal alignment, which may contribute to the prevention of ASD, resulting in favorable long-term surgical outcomes.

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  • Prevalence of groin pain in unicycle athletes: A nationwide questionnaire survey 国際誌

    Daigo Kobayashi, Naomi Kobayashi, Takayuki Oishi, Hyonmin Choe, Taro Tezuka, Shota Higashihira, Yutaka Inaba

    JOURNAL OF ORTHOPAEDIC SURGERY   28 ( 2 )   2309499020934201 - 2309499020934201   2020年5月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)   出版者・発行元:SAGE PUBLICATIONS LTD  

    Background and purpose: This nationwide questionnaire survey was performed to clarify the prevalence of groin pain in unicycle athletes and to reveal the relationship between groin pain and factors such as age or athletic career. Patients and methods: To evaluate the prevalence of groin pain, the questionnaire was sent to 1304 unicyclists belonging to the Japan Unicycle Association. All subjects aged 6 years or older at the time they answered the questionnaire. Results: Overall, 17% of unicyclists complained of groin pain. Pain was more common in those aged 13-19 years and in those with a career lasting more than 6 years. Conclusion: The incidence of groin pain (17%) among unicyclists is higher than that among athletes participating in other sports. Unicyclists aged between 13 and 19 years old and those with an athletic career of more than 6 years often suffer from groin pain.

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  • Evaluation of anterior inferior iliac spine impingement after hip arthroscopic osteochondroplasty using computer simulation analysis 国際誌

    Naomi Kobayashi, Hyonmin Choe, Hiroyuki Ike, Shota Higashihira, Daigo Kobayashi, Shintaro Watanabe, So Kubota, Yutaka Inaba

    JOURNAL OF ORTHOPAEDIC SURGERY   28 ( 2 )   2309499020935533 - 2309499020935533   2020年5月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)   出版者・発行元:SAGE PUBLICATIONS LTD  

    Background: Anterior inferior iliac spine (AIIS) impingement is an important risk factor for revision hip arthroscopy. Although a morphological classification system is available, evaluating AIIS impingement with respect to joint kinematics remains a challenge. Purpose: To use computer simulation analysis to ascertain the prevalence of AIIS impingement before and after osteochondroplasty. Methods: A total of 35 joints from 30 cases (20 males and 10 females; average age: 43.3 +/- 13.7 years) were analyzed. All joints had cam morphology and underwent hip arthroscopic osteochondroplasty. A three-dimensional model of each joint was constructed pre- and postoperatively. Joint kinematic simulation software (ZedHip (R), Lexi, Tokyo) was used to identify the impingement point on the acetabular side and the incidence (expressed as a percentage) of AIIS impingement calculated. Radiographic and clinical evaluation was performed pre- and postoperatively. Results: AIIS impingement was observed postoperatively in six joints but preoperatively in only one joint. The rate of AIIS postoperative impingement was significantly higher than that of preoperative impingement. All impingement points were located on the inferior aspect of the AIIS apex. However, there were no significant differences between the AIIS impingement and non-impingement groups in terms of clinical outcome. Conclusion: The incidence of AIIS impingement after osteochondroplasty was 17% by computer simulation analysis. Osteochondroplasty may result in subsequent AIIS impingement.

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  • Utility of CT-based navigation in revision total hip arthroplasty for a patient with severe posterior pelvic tilt-case report. 国際誌

    Shota Higashihira

    BMC musculoskeletal disorders   21 ( 1 )   249 - 249   2020年4月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)  

    BACKGROUND:Hip dislocation after total hip arthroplasty (THA) or hemi-arthroplasty is a rare but serious complication. Dislocation may be prevented by appropriate positioning of the cup angle of inclination and anteversion. CASE PRESENTATION:This report describes a 66-year-old woman who underwent revision THA using a computer tomography (CT)-based navigation system to treat an anterior dislocation after hemi-arthroplasty due to a severe posterior pelvic tilt. At initial presentation, her sagittal pelvic tilt angle, measured as anterior pelvic plane (APP) in the supine position, was 38 degrees posterior to the coronal plane. Owing to the posterior pelvic tilt, revision THA was performed using CT-based navigation, while dual mobility was utilized to reduce the risk of re-dislocation. Postoperatively, her sagittal pelvic tilt angle showed further progression over time, with an APP of 66 degrees posterior to the coronal plane in the standing position 3 years after revision THA. Simulation with the Zed Hip system showed that the risk of implant-to-implant impingement was much higher posteriorly than anteriorly. Gait analysis demonstrated hyperextension of the hip joint while walking, although hip joint function required for daily activity was maintained. CONCLUSIONS:Preoperative planning of implant orientation, based on posterior progression of pelvic tilt and accurate placement of components, is important to prevent dislocation in patients with severe posterior pelvic tilt. A dual mobility cup may also improve hip function in these patients.

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  • Effect of switching administration of alendronate after teriparatide for the prevention of BMD loss around the implant after total hip arthroplasty, 2-year follow-up: a randomized controlled trial 国際誌

    Akira Morita, Naomi Kobayashi, Hyonmin Choe, Hiroyuki Ike, Taro Tezuka, Shota Higashihira, Yutaka Inaba

    JOURNAL OF ORTHOPAEDIC SURGERY AND RESEARCH   15 ( 1 )   17 - 17   2020年1月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)   出版者・発行元:BMC  

    Background Stress shielding after total hip arthroplasty (THA) can induce bone mineral density (BMD) loss around the femoral implant. Several studies using drug have described methods to prevent BMD loss around implants following THA. Switching from teriparatide to alendronate was reported to increase lumbar BMD; on the other hands, it is unclear whether switching from teriparatide to alendronate is effective around the implant. The aim of this study is that changes in BMD is compared in patients switched from teriparatide to alendronate, in patients treated with alendronate alone, and in control patients without medication after total hip arthroplasty. Patients and methods Patients were randomized into three groups, those switched to alendronate after teriparatide (switch: n = 17), those receiving continuous alendronate (ALD: n = 15), and control untreated patients (control: n = 16) and followed up for 2 years after THA. Baseline periprosthetic BMD was measured by dual-energy X-ray absorptiometry (DEXA) 1 week after THA, followed by subsequent measurements at 1 and 2 years postoperatively. Lumbar BMD was also evaluated at preoperatively, 1 and 2 years postoperatively. Results Two years after surgery, BMD (%) at zone 1 was significantly higher in the switch group than in the control group (P = 0.02). BMD (%) at zone 7 was significantly higher in the switch and ALD groups than in the control group (P = 0.01, P = 0.03). Lumbar BMD (%) anterior-posterior (AP) side was significantly higher in the switch group than in the ALD and control groups 2 years after surgery. On the other hand, lumbar BMD (%) lateral side was significantly higher in the switch and ALD groups than control group 2 years after surgery. Conclusions Switching therapy had a significant effect on BMD of the lumbar spine and zones 1 and 7 at 2 years postoperatively. At zone 1 in particular, it was found to be more effective than ALD alone.

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  • Comparison Between 3-Dimensional Multiple-Echo Recombined Gradient Echo Magnetic Resonance Imaging and Arthroscopic Findings for the Evaluation of Acetabular Labrum Tear 国際誌

    Shota Higashihira, Naomi Kobayashi, Takayuki Oishi, Hyonmin Choe, Hiroyuki Ike, Taro Tezuka, Yutaka Inaba

    ARTHROSCOPY-THE JOURNAL OF ARTHROSCOPIC AND RELATED SURGERY   35 ( 10 )   2857 - 2865   2019年10月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)   出版者・発行元:W B SAUNDERS CO-ELSEVIER INC  

    Purpose: To evaluate radially reconstructed 3.0-Tesla 3-dimensional multiple-echo recombined gradient echo (MERGE) magnetic resonance imaging (MRI) without arthrography for the assessment of acetabular labrum tears, using arthroscopic evaluation as the reference standard. Methods: A total of 71 consecutive hips, including 29 with femoroacetabular impingement, 26 with borderline developmental dysplasia of the hip, and 16 with early-stage osteoarthritis, were evaluated in this retrospective study. MERGE MRI findings were evaluated according to the modified Czerny classification for 3 regions of interest: anterior region, anterolateral region, and lateral region. Cases with severe degeneration that was not concordant with any stage in the original Czerny classification were defined as stage IV. MERGE MRI findings were compared with arthroscopic findings, and the sensitivity, specificity, positive predictive value, and negative predictive value in terms of the existence of labrum tears were calculated. Results: MERGE MRI findings revealed labrum tears more frequently in the anterolateral region than in the anterior and lateral regions (P < .01). In cases of femoroacetabular impingement and borderline developmental dysplasia of the hip in particular, labrum tears were more frequently observed on MRI in the anterolateral region than in the lateral region (P < .05). In comparison with MRI findings and arthroscopic findings, our newly defined stage IV in the modified Czerny classification was more frequently observed in cases with a Multicenter Arthroscopy of the Hip Outcomes Research Network (MAHORN) classification of degenerative or complex (P < .01). The average sensitivity and specificity of all regions for the existence of labrum tears were 85% and 56%, respectively. Sensitivity and specificity were 79% and 50%, respectively, in the anterior region; 96% and 50%, respectively, in the anterolateral region; and 70% and 57%, respectively, in the lateral region. Conclusions: We validated the diagnostic performance of 3.0-Tesla 3-dimensional MERGE MRI for evaluating acetabular labrum tears and made comparisons with arthroscopic findings. Radially reconstructed MERGE magnetic resonance images showed excellent sensitivity for the diagnosis of labrum tears, particularly in the anterolateral region. The newly defined stage IV was distinctive of early-stage osteoarthritis cases with degeneration and/or complex arthroscopic findings. The noninvasive imaging modality of radially reconstructed MERGE MRI may be an alternative to magnetic resonance arthrography for evaluating labrum tears.

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  • Posterior acetabular uptake on F-18-fluoride positron emission tomography/computed tomography reveals a putative contrecoup region in patients with femoroacetabular impingement 国際誌

    Takayuki Oishi, Naomi Kobayashi, Hyonmin Choe, Taro Tezuka, Daigo Kobayashi, Shota Higashihira, Yutaka Inaba

    JOURNAL OF ORTHOPAEDIC SURGERY   27 ( 3 )   2309499019868929 - 2309499019868929   2019年9月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)   出版者・発行元:SAGE PUBLICATIONS LTD  

    Background and purpose: The pathology of the posterior acetabular lesions, so-called "contrecoup regions", in femorocacetabular impingement (FAI) has not been elucidated fully. F-18-fluoride positron emission tomography/computed tomography (PET/CT) can visualize abnormal uptake caused by impingement. Therefore, we aimed to evaluate posterior acetabular uptake on PET/CT in FAI patients. Patients and methods: Patients with FAI who underwent F-18-fluoride PET/CT between October 2014 and October 2016 were retrospectively evaluated. The maximum standardized uptake value (SUVmax) in the posterior acetabulum was evaluated. The mean SUVmax of FAI with cam morphology (the cam group) was compared with that of FAI with pincer morphology (the pincer group). In addition, the numbers of cases with SUVmax >= 6 and SUVmax < 6 in each group were evaluated. The entire study cohort was also grouped according to SUVmax, and the mean alpha and center edge angles were evaluated. Results: In total, 41 hips were analyzed (34 hips in the cam group and 7 in the pincer group). The mean SUVmax of the cam group (11.2 +/- 7.4) was significantly higher than that of the pincer group (4.9 +/- 1.9) (p < 0.01). The incidence of cases with SUVmax >= 6 in the cam group was significantly high (p < 0.01). In the overall cohort, the mean alpha angle of the SUVmax >= 6 group was significantly higher than that of the SUVmax < 6 group (p < 0.01). Conclusion: Evaluation of posterior acetabular uptake suggests an association between cam morphology and increased posterior acetabular uptake.

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  • FAIにおけるAIIS(下前腸骨棘)の形態的評価 3D解析による検討

    高橋 実来, 小林 直実, 稲葉 裕, 崔 賢民, 久保田 聡, 大石 隆幸, 小林 大悟, 渡部 慎太郎, 東平 翔太, 齋藤 知行

    Hip Joint   44 ( 2 )   4 - 4   2018年8月

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    記述言語:日本語   出版者・発行元:日本股関節学会  

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  • The influence of patient factors on femoral rotation after total hip arthroplasty. 国際誌

    Taro Tezuka, Yutaka Inaba, Naomi Kobayashi, Hyonmin Choe, Syota Higashihira, Tomoyuki Saito

    BMC musculoskeletal disorders   19 ( 1 )   189 - 189   2018年6月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)  

    BACKGROUND: A postoperative change in femoral rotation following total hip arthroplasty (THA) might be the cause of dislocation due to the change in combined anteversion. However, very few studies have evaluated the femoral rotation angle following THA, or the factors that influence femoral rotation. We aimed to evaluate changes in femoral rotation after THA, and to investigate preoperative patient factors that influence femoral rotation after THA. METHODS: This study involved 211 hips treated with primary THA. We used computed tomography to measure the femoral rotation angle before and one week after THA. In addition, multiple regression analysis was performed to evaluate preoperative patient factors that could influence femoral rotation after THA. RESULTS: The femoral rotation angle was 0.2 ± 14° externally before surgery and 4.4 ± 12° internally after surgery (p < 0.001). Multiple regression analysis revealed that sex (β = 0.19; p = 0.003), age (β = 0.15; p = 0.017), preoperative anatomical femoral anteversion (β = - 0.25; p = 0.002), and preoperative femoral rotation angle (β = 0.36; p < 0.001) were significantly associated with the postoperative femoral rotation angle. The final model of the regression formula was described by the following equation: [postoperative femoral rotation angle = 5.41 × sex (female: 0, male: 1) + 0.15 × age - 0.22 × preoperative anatomical femoral anteversion + 0.33 × preoperative femoral rotation angle - 10.1]. CONCLUSION: The current study showed the mean internal change of 4.6° in the femoral rotation angle one week after THA. Sex, age, preoperative anatomical femoral anteversion and preoperative femoral rotation were associated with postoperative femoral rotation. The patients who were male, older, and who exhibited lesser preoperative anatomical femoral anteversion or greater preoperative femoral rotation angles, tended to demonstrate an externally rotated femur after THA. Conversely, patients who were female, younger, and who exhibited greater preoperative anatomical femoral anteversion or lesser preoperative femoral rotation angles, tended to demonstrate an internal rotation of the femur after THA.

    DOI: 10.1186/s12891-018-2110-y

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  • FAI症例における18F-fluoride PET/CTによる寛骨臼後方集積(contre-coup resion)の評価

    大石 隆幸, 小林 直実, 稲葉 裕, 小林 大悟, 東平 翔太, 齋藤 知行

    JOSKAS   43 ( 4 )   193 - 193   2018年5月

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    記述言語:日本語   出版者・発行元:(一社)日本関節鏡・膝・スポーツ整形外科学会  

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  • Computer-Assisted Hip Arthroscopic Surgery for Femoroacetabular Impingement 国際誌

    Naomi Kobayashi, Yutaka Inaba, So Kubota, Shota Higashihira, Hyonmin Choe, Hiroyuki Ike, Daigo Kobayashi, Tomoyuki Saito

    ARTHROSCOPY TECHNIQUES   7 ( 4 )   E397 - E403   2018年4月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)   出版者・発行元:ELSEVIER SCIENCE BV  

    Precise osteochondroplasty is key for success in hip arthroscopic surgery, especially for femoroacetabular impingement (FAI) caused by cam or pincer morphology. In this Technical Note, we present computer-assisted hip arthroscopic surgery for FAI, including preoperative planning by virtual osteochondroplasty and intraoperative computer navigation assistance. The important concept of this technique is that navigation assistance for osteochondroplasty is based on planning made by computer simulation analysis. The navigation assistance allows us to perform neither too much nor too little osteochondroplasty. Specifically, computer simulation was used to identify the impingement point. Virtual osteochondroplasty was then performed to determine the maneuvers that would improve range of motion. Thereafter, the planning data were transported to a computed tomography-based computer navigation system that directly provided intraoperative assistance. Thus, computer-assisted technology including preoperative simulation, virtual osteochondroplasty planning, and intraoperative navigation assistance may promote precise hip arthroscopic surgery for FAI.

    DOI: 10.1016/j.eats.2017.10.013

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▼全件表示

MISC

  • 股関節鏡手術の術前計画とコンピュータ支援技術—Preoperative Planning and Computer Assisted Surgery for Hip Arthroscopy—特集 股関節鏡手術のエビデンス : 治療成績の現状

    小林 直実, 本田 秀樹, 雪澤 洋平, 東平 翔太, 加茂野 絵美

    臨床整形外科   58 ( 7 )   891 - 898   2023年7月

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    記述言語:日本語   出版者・発行元:東京 : 医学書院  

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    その他リンク: https://ndlsearch.ndl.go.jp/books/R000000004-I032950555

  • 境界型寛骨臼形成不全のアスリートにおける股関節鏡視下手術のスポーツ復帰率:システマティックレビューとメタ解析による検討

    齊藤昌愛, 齊藤昌愛, 齊藤昌愛, 小林直実, 山本剛裕, 加茂野絵美, 東平翔太, 雪澤洋平, 稲葉裕

    日本股関節学会学術集会プログラム・抄録集   50th   2023年

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  • Dorr type別におけるZweymuller type stemとtaper wedge type stemの人工股関節周囲骨密度変化の比較

    森田 彰, 小林 直実, 崔 賢民, 手塚 太郎, 池 裕之, 大庭 真俊, 東平 翔太, 安部 晃生, 稲葉 裕

    日本整形外科学会雑誌   95 ( 8 )   S1663 - S1663   2021年8月

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    記述言語:日本語   出版者・発行元:(公社)日本整形外科学会  

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  • 大腿骨髄腔形状別におけるZweymuller type stemとTaper wedge type stemの人工股関節周囲骨密度の比較

    森田彰, 小林直実, 崔賢民, 池裕之, 大庭真俊, 手塚太郎, 東平翔太, 安部晃生, 稲葉裕

    日本人工関節学会プログラム・抄録集   51st   2021年

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  • 人工股関節置換後インプラント周囲骨密度低下の予防-ランダム化比較試験 デノスマブvsゾレドロン酸-

    森田彰, 小林直実, 崔賢民, 池裕之, 手塚太郎, 東平翔太, 安部晃生, 稲葉裕

    日本股関節学会学術集会プログラム・抄録集   48th   2021年

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  • 人工股関節全置換術患者におけるステム周囲の術後骨密度低下に関連する術前因子の検討

    森田 彰, 小林 直実, 崔 賢民, 手塚 太郎, 大庭 真俊, 宮前 祐之, 東平 翔太, 安部 晃生, 稲葉 裕

    日本整形外科学会雑誌   94 ( 8 )   S1890 - S1890   2020年9月

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    記述言語:日本語   出版者・発行元:(公社)日本整形外科学会  

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  • 連載 最新原著レビュー 3D multiple-echo recombined gradient echo(MERGE)MRIによる股関節唇損傷評価

    東平 翔太, 小林 直実

    整形外科   71 ( 8 )   931 - 934   2020年7月

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    出版者・発行元:南江堂  

    DOI: 10.15106/j_seikei71_931

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  • 最新原著レビュー 3D multiple-echo recombined gradient echo (MERGE) MRIによる股関節唇損傷評価 : 関節鏡視下所見との比較—Comparison between 3-dimensional multiple-echo recombined gradient echo magnetic resonance imaging and arthroscopic findings for the evaluation of acetabular labrum tear

    東平 翔太, 小林 直実

    整形外科 = Orthopedic surgery : 臨床雑誌   71 ( 8 )   931 - 934   2020年7月

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    記述言語:日本語   出版者・発行元:南江堂  

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  • 人工股関節全置換術後Zone7の骨密度低下に関連する術前因子の検討

    森田彰, 小林直実, 崔賢民, 大庭真俊, 宮前祐之, 東平翔太, 安部晃生, 稲葉裕

    日本人工関節学会プログラム・抄録集   50th   2020年

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  • THA後のインプラント周囲骨密度低下に対するPTH投与後ALDへ治療薬をswitchした効果

    森田 彰, 小林 直実, 崔 賢民, 池 裕之, 手塚 太郎, 東平 翔太, 稲葉 裕

    日本整形外科学会雑誌   93 ( 8 )   S1914 - S1914   2019年9月

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    記述言語:日本語   出版者・発行元:(公社)日本整形外科学会  

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  • THA後のインプラント周囲骨密度低下に対するPTH投与後ALDへ治療薬をswitchした効果

    森田 彰, 小林 直実, 崔 賢民, 池 裕之, 手塚 太郎, 東平 翔太, 稲葉 裕

    日本整形外科学会雑誌   93 ( 8 )   S1914 - S1914   2019年9月

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    記述言語:日本語   出版者・発行元:(公社)日本整形外科学会  

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  • 人工関節周囲感染とインプラント温存

    崔 賢民, 小林 直実, 池 裕之, 手塚 太郎, 東平 翔太, 森田 彰, 稲葉 裕

    関東整形災害外科学会雑誌   50 ( 4 )   237 - 237   2019年8月

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    記述言語:日本語   出版者・発行元:関東整形災害外科学会  

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  • 人工関節周囲感染とインプラント温存

    崔 賢民, 小林 直実, 池 裕之, 手塚 太郎, 東平 翔太, 森田 彰, 稲葉 裕

    関東整形災害外科学会雑誌   50 ( 4 )   237 - 237   2019年8月

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    記述言語:日本語   出版者・発行元:関東整形災害外科学会  

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  • DDHに対する骨切り術後に生じたArthrofibrosisに対して股関節鏡による受動術が有効であった一例

    森田 彰, 小林 直実, 崔 賢民, 池 裕之, 大庭 真俊, 手塚 太郎, 東平 翔太, 安部 晃生, 稲葉 裕

    東日本整形災害外科学会雑誌   31 ( 3 )   363 - 363   2019年8月

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    記述言語:日本語   出版者・発行元:東日本整形災害外科学会  

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  • FAI症例における18F-fluoride PET/CTによる寛骨臼後方集積(contre-coup region)の評価

    大石 隆幸, 小林 直実, 小林 大悟, 東平 翔太, 稲葉 裕

    JOSKAS   44 ( 3 )   631 - 635   2019年6月

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    記述言語:日本語   出版者・発行元:(一社)日本関節鏡・膝・スポーツ整形外科学会  

    【目的】本研究の目的はfemoroacetabular impingement(FAI)症例において18F-fluoride positron emission tomography/computed tomography(PET/CT)を用いて寛骨臼後方の異常集積を調査し,FAIのタイプによる集積値の違いを明らかにすることである.【対象および方法】臨床的にFAIが疑われ18F-fluoride PET/CTを撮影した41股41例を対象とした.個々の症例について寛骨臼後方のmaximum standardized uptake value(SUVmax)を計測した.対象をcam-type,pincer-type,combined-type,developmental dysplasia of the hip(DDH) with cam morphologyの4タイプに分類し,各タイプにおける平均SUVmaxと各タイプにおけるSUVmax 6以上および6未満の症例数を調査した.また,全対象をSUVmax 6以上と6未満の群に分け,それぞれの平均α角および平均center edge(CE)角を調査した.【結果】平均SUVmaxはpincer-typeが他の3タイプと比較して有意に小さな値であり(p<0.05),DDH withcam morphologyが最も大きかった.Pincer-typeにおいてSUVmax 6以上の症例数が有意に少なく,SUVmax6未満の症例数が有意に多かった(p<0.01).全対象をSUVmax 6以上と6未満の2群に分けると,6以上の群で6未満の群に比較して平均α角が有意に大きかった(p=0.024).【結語】本研究では,18F-fluoride PET/CTを用いてFAI症例の寛骨臼後方集積を評価し,FAIのタイプによる集積値の違いを検討した.FAI症例における寛骨臼後方の集積は,cam形態と関連していることが示唆された.(著者抄録)

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  • 大腿骨頸部に合併したFAIと骨芽細胞腫の稀な一例

    森田 彰, 小林 直実, 崔 賢民, 池 裕之, 手塚 太郎, 東平 翔太, 稲葉 裕

    JOSKAS   44 ( 4 )   531 - 531   2019年5月

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    記述言語:日本語   出版者・発行元:(一社)日本関節鏡・膝・スポーツ整形外科学会  

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  • 骨盤後傾はFAI、境界型寛骨臼形成不全におけるインピンジメントに影響するか?

    東平 翔太, 小林 直実, 崔 賢民, 池 裕之, 手塚 太郎, 森田 彰, 稲葉 裕

    JOSKAS   44 ( 4 )   531 - 531   2019年5月

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    記述言語:日本語   出版者・発行元:(一社)日本関節鏡・膝・スポーツ整形外科学会  

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  • 整形トピックス 股関節唇損傷診断におけるMERGE MRIの有用性の検討

    東平 翔太, 小林 直実, 稲葉 裕

    整形外科   70 ( 4 )   332 - 332   2019年4月

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    出版者・発行元:南江堂  

    DOI: 10.15106/j_seikei70_332

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  • 超音波検査による人工股関節周囲組織の画像評価 表面置換型人工股関節置換術患者におけるMRI所見との比較

    崔 賢民, 小林 直実, 池 裕之, 手塚 太郎, 東平 翔太, 森田 彰, 稲葉 裕

    日本整形外科学会雑誌   93 ( 3 )   S893 - S893   2019年3月

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    記述言語:日本語   出版者・発行元:(公社)日本整形外科学会  

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  • 人工股関節全置換術後のプロテインS活性の変化と静脈血栓塞栓症の発生に与える影響

    手塚 太郎, 小林 直実, 崔 賢民, 池 裕之, 東平 翔太, 森田 彰, 稲葉 裕

    日本整形外科学会雑誌   93 ( 2 )   S264 - S264   2019年3月

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    記述言語:日本語   出版者・発行元:(公社)日本整形外科学会  

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  • THA後のテリパラチド/アレンドロネートスイッチおよびアレンドロネート持続のインプラント周囲骨密度変化

    森田 彰, 小林 直実, 崔 賢民, 池 裕之, 手塚 太郎, 東平 翔太, 稲葉 裕

    日本整形外科学会雑誌   93 ( 3 )   S660 - S660   2019年3月

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    記述言語:日本語   出版者・発行元:(公社)日本整形外科学会  

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  • 人工関節周囲感染(PJI)の予防と対策 PJIの診断 現状のupdateと今後の課題

    小林 直実, 崔 賢民, 池 裕之, 手塚 太郎, 友山 瑛人, 渡部 慎太郎, 東平 翔太, 森田 彰, 稲葉 裕

    日本整形外科学会雑誌   93 ( 2 )   S337 - S337   2019年3月

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    記述言語:日本語   出版者・発行元:(公社)日本整形外科学会  

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  • SL-PLUS MIA stemにおけるhydroxyapatiteコーティングの効果

    池 裕之, 小林 直実, 崔 賢民, 手塚 太郎, 東平 翔太, 森田 彰, 稲葉 裕

    日本整形外科学会雑誌   93 ( 3 )   S1206 - S1206   2019年3月

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    記述言語:日本語   出版者・発行元:(公社)日本整形外科学会  

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  • 人工股関節全置換術患者における大腿骨回旋角の変化

    小林 大悟, 齋藤 泉, 崔 賢民, 小林 直実, 手塚 太郎, 池 裕之, 東平 翔太, 森田 彰, 稲葉 裕

    日本整形外科学会雑誌   93 ( 3 )   S899 - S899   2019年3月

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    記述言語:日本語   出版者・発行元:(公社)日本整形外科学会  

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  • 人工股関節周囲感染に対する二期的人工股関節再置換術の術後股関節機能 一期的再置換術との比較

    崔 賢民, 小林 直実, 池 裕之, 手塚 太郎, 東平 翔太, 森田 彰, 稲葉 裕

    日本整形外科学会雑誌   93 ( 2 )   S262 - S262   2019年3月

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    記述言語:日本語   出版者・発行元:(公社)日本整形外科学会  

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  • FAIに合併した大腿骨頸部後方の骨芽細胞腫の一例

    森田 彰, 小林 直実, 崔 賢民, 池 裕之, 手塚 太郎, 東平 翔太, 稲葉 裕

    関東整形災害外科学会雑誌   50 ( 臨増号外 )   181 - 181   2019年3月

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    記述言語:日本語   出版者・発行元:関東整形災害外科学会  

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  • 人工関節周囲感染とインプラント温存

    崔 賢民, 小林 直実, 池 裕之, 手塚 太郎, 東平 翔太, 森田 彰, 稲葉 裕

    関東整形災害外科学会雑誌   50 ( 臨増号外 )   61 - 61   2019年3月

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    記述言語:日本語   出版者・発行元:関東整形災害外科学会  

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  • 骨盤後傾を考慮したFAI,境界型寛骨臼形成不全におけるインピンジメント評価-CAM切除後CT画像との比較検討-

    東平翔太, 小林直実, 大石隆幸, 雪澤洋平, 崔賢民, 手塚太郎, 大庭真俊, 森田彰, 安部晃生, 稲葉裕

    日本股関節学会学術集会プログラム・抄録集   46th   2019年

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  • 3.0 Tesla Multiple Echo Recombined Gradient Echo MRIによる関節唇損傷診断の有用性—─鏡視下所見との比較検討─

    東平 翔太, 小林 直実, 大石 隆幸, 崔 賢民, 池 裕之, 稲葉 裕

    東日本整形災害外科学会雑誌   31 ( 1 )   61 - 65   2019年

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    記述言語:日本語   出版者・発行元:東日本整形災害外科学会  

    3.0 Tesla(以下 3T)Multiple Echo Recombined Gradient Echo(MERGE)MRIを用いて股関節唇をmodified Czerny分類で評価した.鏡視下所見と比較し,関節唇損傷診断におけるMERGE MRIの診断能を検討した.関節唇損傷は前外側に好発し,前方と前外側では感度90%以上,特異度100%であり,MERGE MRIの有用性が示された.

    DOI: 10.24645/jejot.31.1_61

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    その他リンク: https://search.jamas.or.jp/link/ui/2019247310

  • 人工股関節全置換術におけるプロテインSの術後変化

    池 裕之, 稲葉 裕, 小林 直実, 雪澤 洋平, 崔 賢民, 久保田 聡, 小林 大悟, 渡部 慎太郎, 東平 翔太, 齋藤 知行

    静脈学   29 ( 2 )   137 - 137   2018年5月

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    記述言語:日本語   出版者・発行元:日本静脈学会  

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  • 一輪車競技者における股関節障害の疫学調査

    小林 大悟, 小林 直実, 稲葉 裕, 東平 翔太, 齋藤 知行

    JOSKAS   43 ( 4 )   194 - 194   2018年5月

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    記述言語:日本語   出版者・発行元:(一社)日本関節鏡・膝・スポーツ整形外科学会  

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  • FAI症例における18F-fluoride PET/CTによる寛骨臼後方集積(contre-coup resion)の評価

    大石 隆幸, 小林 直実, 稲葉 裕, 小林 大悟, 東平 翔太, 齋藤 知行

    JOSKAS   43 ( 4 )   193 - 193   2018年5月

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    記述言語:日本語   出版者・発行元:(一社)日本関節鏡・膝・スポーツ整形外科学会  

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  • 関節唇を考慮した3次元動態シミュレーションによるFAI、Borderline DDHにおけるインピンジメントの比較

    東平 翔太, 小林 直実, 稲葉 裕, 小林 大悟, 齋藤 知行

    JOSKAS   43 ( 4 )   191 - 191   2018年5月

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    記述言語:日本語   出版者・発行元:(一社)日本関節鏡・膝・スポーツ整形外科学会  

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  • 人工股関節全置換術患者における立位から座位への姿勢の変化が骨盤傾斜に与える影響

    渡部慎太郎, 稲葉裕, 小林直実, 崔賢民, 池裕之, 小林大悟, 東平翔太, 齋藤知行

    日本整形外科学会雑誌   92 ( 2 )   S264 - S264   2018年3月

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    記述言語:日本語   出版者・発行元:(公社)日本整形外科学会  

    J-GLOBAL

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  • FAI、境界型寛骨臼形成不全、初期OAにおける股関節唇断裂所見の比較 放射状3D MERGE MRIによる評価

    東平 翔太, 小林 直実, 稲葉 裕, 大石 隆幸, 崔 賢民, 池 裕之, 小林 大悟, 渡部 慎太郎, 齋藤 知行

    日本整形外科学会雑誌   92 ( 2 )   S105 - S105   2018年3月

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    記述言語:日本語   出版者・発行元:(公社)日本整形外科学会  

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  • EOSシステムを用いた人工股関節全置換術患者の立位時下肢アライメント評価

    小林 大悟, 稲葉 裕, 小林 直実, 崔 賢民, 池 裕之, 渡部 慎太郎, 東平 翔太, 齋藤 知行

    日本整形外科学会雑誌   92 ( 2 )   S263 - S263   2018年3月

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    記述言語:日本語   出版者・発行元:(公社)日本整形外科学会  

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  • 「SSIの予防・診断・治療(インプラント温存を含めて)」 当院における人工股関節置換術患者に対するSSIの予防・診断・治療

    崔 賢民, 稲葉 裕, 小林 直実, 手塚 太郎, 小林 大吾, 渡部 慎太郎, 東平 翔太, 土肥 健人, 齋藤 知行

    神奈川医学会雑誌   45 ( 1 )   99 - 99   2018年1月

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    記述言語:日本語   出版者・発行元:神奈川県医師会  

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  • 11歳男児に発症した大腿骨頸部骨性隆起に対して骨軟骨形成術を施行した一例 術後2年の経過報告

    東平 翔太, 小林 直実, 稲葉 裕, 崔 賢民, 手塚 太郎, 小林 大悟, 渡部 慎太郎, 土肥 健人, 齋藤 知行

    東日本整形災害外科学会雑誌   29 ( 3 )   275 - 275   2017年8月

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    記述言語:日本語   出版者・発行元:東日本整形災害外科学会  

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  • SSIの予防・診断・治療(インプラント温存を含めて) 当院における人工股関節置換術患者に対するSSIの予防・診断・治療

    崔 賢民, 稲葉 裕, 小林 直実, 手塚 太郎, 小林 大吾, 渡部 慎太郎, 東平 翔太, 土肥 健人, 齋藤 知行

    神奈川医学会雑誌   44 ( 2 )   262 - 263   2017年7月

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    記述言語:日本語   出版者・発行元:神奈川県医師会  

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  • SSIの予防・診断・治療(インプラント温存を含めて) 当院における人工股関節置換術患者に対するSSIの予防・診断・治療

    崔 賢民, 稲葉 裕, 小林 直実, 手塚 太郎, 小林 大吾, 渡部 慎太郎, 東平 翔太, 土肥 健人, 齋藤 知行

    神奈川整形災害外科研究会雑誌   30 ( 1 )   16 - 16   2017年6月

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    記述言語:日本語   出版者・発行元:神奈川整形災害外科研究会  

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受賞

  • ORS/OREF Travel Grants in Orthopaedic Research Translation

    2024年   米国整形外科基礎学会  

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  • 優秀論文賞

    2024年   横浜市立大学 整形外科  

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  • Top Silver reviewer

    2024年   Orthopaedics & traumatology: surgery & research  

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  • Top Gold reviewer

    2023年   Orthopaedics & traumatology: surgery & research  

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  • Top Platinum reviewer

    2022年   Orthopaedics & traumatology: surgery & research  

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  • Best Abstract Award

    2021年   Indiana University School of Medicine Postdoc Symposium  

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  • 優秀論文賞 (若手奨励賞)

    2020年   横浜市立大学 整形外科  

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共同研究・競争的資金等の研究課題

  • 変形性関節症における危険因子としての歯周病菌を介した炎症誘導の病態解明

    研究課題/領域番号:25K20016  2025年4月 - 2029年3月

    日本学術振興会  科学研究費助成事業  若手研究

    東平 翔太

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    配分額:4810000円 ( 直接経費:3700000円 、 間接経費:1110000円 )

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  • Diabetes/Metabolic Syndrome Impairs Outcomes of Orthopaedic Implant Infection in Mice

    2022年 - 2023年

    Indiana Center for Diabetes and Metabolic Diseases  Pilot and Feasibility Award Grant (NIH/NIDDK P30 DK097512) 

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    担当区分:研究分担者 

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  • 新薬Halicinを用いた難治性バイオフィルム感染に対する治療戦略

    2022年 - 2023年

    獨協医科大学同窓会  研究助成 

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    担当区分:研究代表者 

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担当経験のある科目(授業)

  • 運動器疾患の症候と病態(整形外科学)

    2023年4月 - 現在 機関名:横浜市立大学

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社会貢献活動

  • Editorial board member; BMC musculoskeletal disorders

    役割:編集

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学術貢献活動

  • Orthopaedics & Traumatology: Surgery & Research

    役割:査読

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  • Clinical Orthopaedics and Related Research

    役割:査読

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  • Scientific reports

    役割:査読

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  • Orthopaedic Research Society

    役割:査読

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  • Journal of orthopaedic research

    役割:査読

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  • Journal of orthopaedic surgery and research

    役割:査読

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  • BMC musculoskeletal disorders

    役割:査読

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  • Journal of clinical orthopaedics and trauma

    役割:査読

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  • Bone & joint research

    役割:査読

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  • European journal of orthopaedic surgery & traumatology

    役割:査読

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