Updated on 2025/11/10

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写真a

 
Nao Tamai
 
Organization
Graduate School of Medicine Department of Nursing Professor
School of Medicine Nursing Course
Title
Professor
Homepage
https://ycu-seijinkango.jp/
External link

Degree

  • Doctor ( 2012.3   The University of Tokyo )

Research Interests

  • Cancer Nursing, Wound Care Nursing, Visualized Nursing, Nursing Science and Engineering

Research Areas

  • Life Science / Clinical nursing  / Cancer Nursing, Wound Care Nursing, Visualized Nursing, Nursing Science and Engineering

Education

  • The University of Tokyo

    2009.4 - 2012.3

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    Country： Japan

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  • 金沢大学大学院   医学系研究科   保健学専攻看護学領域

    2001.4 - 2003.3

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    Country： Japan

    Notes： 修士（保健学）

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  • Kanazawa University

    1997.4 - 2001.3

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    Country： Japan

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Research History

  • Yokohama City University   Professor

    2022.4

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  • 東京大学大学院   医学系研究科 社会連携講座イメージング看護学   特任准教授

    2019.4 - 2022.3

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    Country：Japan

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  • 東京大学大学院   医学系研究科 社会連携講座スキンケアサイエンス   特任講師

    2017.2 - 2019.3

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    Country：Japan

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  • 東京大学大学院   医学系研究科 健康科学・看護学専攻 老年看護学分野   助教

    2012.12 - 2017.1

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    Country：Japan

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  • 東京大学大学院   医学系研究科ライフサポート技術開発学（モルテン）寄付講座   特任助教

    2012.4 - 2012.11

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    Country：Japan

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  • （財）聖路加国際病院   看護部   看護師

    2003.4 - 2009.3

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    Country：Japan

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Committee Memberships

  • 公益社団法人日本看護科学学会   看護ケア開発・標準化委員会「看護ケアのための高齢者の便秘時の大腸便貯留アセスメントに関する診療ガイドライン」パネル会議メンバー  

    2022.12 - 2023.6   

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  • 一般社団法人日本看護研究学会   第49回学術集会 企画委員  

    2022.5 - 2023.8   

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  • 看護理工学会   関連学会連絡委員会 委員  

    2022.2   

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  • 公益社団法人日本看護科学学会   和文誌専任査読委員  

    2021.10   

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  • 一般社団法人日本創傷・オストミー・失禁管理学会   便秘対策アドホック委員会 委員  

    2021.9   

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  • 公益社団法人日本看護科学学会   看護ケア開発・標準化委員会「看護ケアのための高齢者の便秘時の大腸便貯留アセスメントに関する診療ガイドライン」作成グループメンバー  

    2021.9 - 2023.6   

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  • 一般社団法人日本在宅ケア学会   在宅ケアイノベーション研究研修委員会 委員  

    2021.7   

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  • 第31回日本医学会総会   展示委員会 WG委員  

    2020.11 - 2023.12   

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  • 日本家族療法学会   第37回大会 実行委員  

    2020.9   

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  • 第30回日本創傷・オストミー・失禁管理学会/The 9th Asian pacific Enterostomal Therapy Nurse Association（合同開催）   実行委員長  

    2019.7 - 2021.7   

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  • 一般社団法人日本褥瘡学会   車いすアスリート支援委員会 委員  

    2019.3   

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  • 公益社団法人日本看護科学学会   看護ケア開発・標準化委員会「摂食嚥下時の誤嚥・残留アセスメントに関する看護ケア（仮）」ガイドライン作成システマティックレビューメンバー  

    2018.4 - 2019.6   

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  • 看護理工学会   評議員  

    2017.10   

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  • 一般社団法人聖路加看護学会   選挙管理委員会 委員  

    2017.5 - 2020.11   

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  • 日本創傷・オストミー・失禁管理学会   評議員  

    2017.4   

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  • 一般社団法人聖路加看護学会   学術交流委員会 委員  

    2016.11 - 2020.6   

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  • 第25回日本創傷・オストミー・失禁管理学会   学術集会 協力委員  

    2016.6   

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  • 第46回日本創傷治癒学会   実行委員  

    2015.12 - 2016.12   

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  • 看護理工学会   倫理委員会 委員  

    2014.1 - 2016   

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  • 看護実践学会   査読委員  

    2013.4   

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  • 第1回看護理工学会   学術集会 実行委員  

    2012.10 - 2013.10   

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  • 日本家族看護学会   第19回学術集会 主催校協力委員  

    2012.5 - 2012.9   

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  • 第20回日本創傷・オストミー・失禁管理学会   学術集会 協力委員  

    2011.5   

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  • 一般社団法人日本創傷・オストミー・失禁管理学会   評議員  

    2010.6   

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  • 一般社団法人日本創傷・オストミー・失禁管理学会   査読委員  

    2010.6   

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  • 第4回日本褥瘡学会   学術集会 実行委員  

    2001.8 - 2002.8   

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Papers

  • Evaluating Accuracy of Rectal Fecal Stool Assessment Using Transgluteal Cleft Approach Ultrasonography. International journal

    Yumi Sano, Masaru Matsumoto, Kazuhiro Akiyama, Katsumi Urata, Natsuki Matsuzaka, Nao Tamai, Yuka Miura, Hiromi Sanada

    Healthcare (Basel, Switzerland)   12 ( 13 )   2024.6

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    Language：English   Publishing type：Research paper (scientific journal)  

    BACKGROUND: Transabdominal ultrasound is used to detect fecal impaction, but the rectum is difficult to visualize without bladder urine or with gastrointestinal gas. OBJECTIVE: We developed a transgluteal cleft approach that is unaffected by these factors and sought to determine if our ultrasound method could detect and classify fecal matter in the lower rectum using this approach. METHODS: We classified ultrasound images from hospitalized patients into four groups: Group 1 (bowed and rock-like echogenic areas), Group 2 (irregular and cotton candy-like hyperechoic areas), Group 3 (flat and mousse-like hyperechoic areas), and Group 4 (linear echogenic areas in the lumen). Stool characteristics were classified as hard, normal, and muddy/watery. Sensitivity and specificity were determined based on fecal impaction and stool classification accuracy. RESULTS: We obtained 129 ultrasound images of 23 patients. The sensitivity and specificity for fecal retention in the rectum were both 100.0%. The recall rates were 71.8% for Group 1, 93.1% for Group 2, 100.0% for Group 3, and 100.0% for Group 4. The precision rates were 96.6% for Group 1, 71.1% for Group 2, 88.9% for Group 3, and 100.0% for Group 4. Our method was 89.9% accurate overall. CONCLUSION: Transgluteal cleft approach ultrasound scanning can detect and classify fecal properties with high accuracy.

    DOI： 10.3390/healthcare12131251

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  • Pelvic floor muscle contraction automatic evaluation algorithm for pelvic floor muscle training biofeedback using self-performed ultrasound

    Miyako Muta, Toshiaki Takahashi, Nao Tamai, Motofumi Suzuki, Atsuo Kawamoto, Hiromi Sanada, Gojiro Nakagami

    BMC Women's Health   24 ( 1 )   2024.4

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    Publishing type：Research paper (scientific journal)   Publisher：Springer Science and Business Media LLC  

    Abstract

    Introduction

    Non-invasive biofeedback of pelvic floor muscle training (PFMT) is required for continuous training in home care. Therefore, we considered self-performed ultrasound (US) in adult women with a handheld US device applied to the bladder. However, US images are difficult to read and require assistance when using US at home. In this study, we aimed to develop an algorithm for the automatic evaluation of pelvic floor muscle (PFM) contraction using self-performed bladder US videos to verify whether it is possible to automatically determine PFM contraction from US videos.

    Methods

    Women aged ≥ 20 years were recruited from the outpatient Urology and Gynecology departments of a general hospital or through snowball sampling. The researcher supported the participants in their self-performed bladder US and videos were obtained several times during PFMT. The US videos obtained were used to develop an automatic evaluation algorithm. Supervised machine learning was then performed using expert PFM contraction classifications as ground truth data. Time-series features were generated from the x- and y-coordinate values of the bladder area including the bladder base. The final model was evaluated for accuracy, area under the curve (AUC), recall, precision, and F1. The contribution of each feature variable to the classification ability of the model was estimated.

    Results

    The 1144 videos obtained from 56 participants were analyzed. We split the data into training and test sets with 7894 time series features. A light gradient boosting machine model (Light GBM) was selected, and the final model resulted in an accuracy of 0.73, AUC = 0.91, recall = 0.66, precision = 0.73, and F1 = 0.73. Movement of the y-coordinate of the bladder base was shown as the most important.

    Conclusion

    This study showed that automated classification of PFM contraction from self-performed US videos is possible with high accuracy.

    DOI： 10.1186/s12905-024-03041-y

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    Other Link： https://link.springer.com/article/10.1186/s12905-024-03041-y/fulltext.html

  • 治療中止と同時に療養の場を選択する進行がん患者とその家族へのがん看護専門看護師による相談支援の実際

    三堀 いずみ, 林 ゑり子, 菅野 雄介, 玉井 奈緒, 渡邉 眞理, 赤瀬 智子

    日本がん看護学会学術集会   38回   170 - 170   2024.2

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    Language：Japanese   Publisher：(一社)日本がん看護学会  

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  • Effectiveness of Vibration Therapy for Hard-to-Heal Wounds in Clinical Study: A Scoping Review

    Daijiro Haba, Mizuho Itabashi, Nao Tamai, Hiromi Tobe, Hiromi Sanada, Gojiro Nakagami

    Chronic Wound Care Management and Research   Volume 11   1 - 12   2024.2

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    Publishing type：Research paper (scientific journal)   Publisher：Informa UK Limited  

    DOI： 10.2147/cwcmr.s423054

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  • 治療中止と同時に療養の場を選択する進行がん患者とその家族へのがん看護専門看護師による相談支援の実際

    三堀 いずみ, 林 ゑり子, 菅野 雄介, 玉井 奈緒, 渡邉 眞理, 赤瀬 智子

    日本がん看護学会誌   37   177 - 186   2023.10

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    Language：Japanese   Publisher：(一社)日本がん看護学会  

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  • 「防ぎきれない褥瘡」の定義策定に向けた検討 超高齢者における予備調査報告

    大桑 麻由美, 青木 和惠, 安部 正敏, 紺家 千津子, 真田 弘美, 玉井 奈緒, 石澤 美保子, 第5期一般社団法人日本創傷・オストミー・失禁管理学会学術教育委員会

    日本創傷・オストミー・失禁管理学会誌   27 ( 3 )   546 - 552   2023.10

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  • 便秘エコーを習得してアセスメント力をアップ(第2回) 便秘エコー 撮影方法と画像の読み方

    松本 勝, 玉井 奈緒, 三浦 由佳, 真田 弘美

    がん看護   28 ( 7 )   651 - 655   2023.9

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  • 【見かた・読みかたがわかると症状と画像が頭でつながる!がん看護に生かす!ナースのはじめてのエコー】はじめに ナースがエコーをできると看護のココが変わる!体内の可視化で早期介入や患者の安心感につながる!

    玉井 奈緒, 真田 弘美

    YORi-SOUがんナーシング   13 ( 3 )   276 - 278   2023.6

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    Language：Japanese   Publisher：(株)メディカ出版  

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  • ポイントオブケア看護エコー最前線 排泄ケアはこう変わる!膀胱エコーの活用

    玉井 奈緒, 松本 勝, 真田 弘美

    超音波医学   50 ( Suppl. )   S500 - S500   2023.4

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    Language：Japanese   Publisher：(公社)日本超音波医学会  

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  • 【US Today 2023 超音波検査・診断最前線 腹部領域の最新動向を中心に】領域別超音波検査・診断・治療のトピックス POCUSのトピックス 看護における超音波検査の活用

    松本 勝, 玉井 奈緒, 三浦 由佳, 真田 弘美

    INNERVISION   38 ( 5 )   19 - 22   2023.4

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    Language：Japanese   Publisher：(株)インナービジョン  

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  • 実践講座 リハビリテーション治療に生かすエコー 排泄ケアにおけるエコーの活用

    玉井 奈緒, 松本 勝, 三浦 由佳, 真田 弘美

    総合リハビリテーション   51 ( 4 )   425 - 431   2023.4

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    Language：Japanese   Publisher：(株)医学書院  

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  • ポイントオブケア看護エコー最前線 エコーを用いた大腸便貯留観察に基づく便秘アセスメントと排便ケア

    松本 勝, 玉井 奈緒, 真田 弘美

    超音波医学   50 ( Suppl. )   S500 - S500   2023.4

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    Language：Japanese   Publisher：(公社)日本超音波医学会  

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  • Effects of ultrasound with an automatic vessel detection system using artificial intelligence on the selection of puncture points among ultrasound beginner clinical nurses

    Mari Abe-Doi, Ryoko Murayama, Toshiaki Takahashi, Masaru Matsumoto, Nao Tamai, Gojiro Nakagami, Hiromi Sanada

    The Journal of Vascular Access   112972982311564 - 112972982311564   2023.3

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    Publishing type：Research paper (scientific journal)   Publisher：SAGE Publications  

    Background:

    Ultrasound guidance increases the success rate of peripheral intravenous catheter placement. However, the longer time required to obtain ultrasound-guided access poses difficulties for ultrasound beginners. Notably, interpretation of ultrasonographic images is considered as one of the main reasons of difficulty in using ultrasound for catheter placement. Therefore, an automatic vessel detection system (AVDS) using artificial intelligence was developed. This study aimed to investigate the effectiveness of AVDS for ultrasound beginners in selecting puncture points and determine suitable users for this system.

    Methods:

    In this crossover experiment involving the use of ultrasound with and without AVDS, we enrolled 10 clinical nurses, including 5 with some experience in peripheral intravenous catheterization using ultrasound-aided methods (categorized as ultrasound beginners) and 5 with no experience in ultrasound and less experience in peripheral intravenous catheterization using conventional methods (categorized as inexperienced). These participants chose two puncture points (those with the largest and second largest diameter) as ideal in each forearm of a healthy volunteer. The results of this study were the time required for the selection of puncture points and the vein diameter of the selected points.

    Results:

    Among ultrasound beginners, the time required for puncture point selection in the right forearm second candidate vein with a small diameter (<3 mm) was significantly shorter when using ultrasound with AVDS than when using it without AVDS (mean, 87 vs 247 s). Among inexperienced nurses, no significant difference in the time required for all puncture point selections was found between the use of ultrasound with and without AVDS. In the vein diameter, significant difference was shown only in the absolute difference at left second candidate among inexperienced participants.

    Conclusion:

    Ultrasonography beginners needed less time to select the puncture points in a small diameter vein using ultrasound with AVDS than without AVDS.

    DOI： 10.1177/11297298231156489

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    Other Link： http://journals.sagepub.com/doi/full-xml/10.1177/11297298231156489

  • 【老年看護学の新しい姿】エコーを用いたアセスメントに基づく高齢者の便秘ケア

    松本 勝, 玉井 奈緒, 三浦 由佳, 高橋 聡明, 北村 言, 真田 弘美

    Geriatric Medicine   61 ( 3 )   221 - 226   2023.3

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    Language：Japanese   Publisher：(株)ライフ・サイエンス  

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  • 3歳児の皮膚炎に対する非紫外線カーボンアーク灯可視光線療法の効果 シングルケース実験研究(Effect of a UV-free, carbon-arc phototherapy on eczema of a 3-year-old child: A single-case experimental study)

    戸部 浩美, 玉井 奈緒, 麦田 裕子, 中井 彩乃, 永田 みさ子, 峰松 健夫, 真田 弘美

    看護理工学会誌   10   76 - 87   2023

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  • 【看護理工学における産学連携研究の現状と取り組み】(第5章)共同研究講座における産学連携研究

    松本 勝, 玉井 奈緒, 三浦 由佳, 真田 弘美

    看護理工学会誌   10 ( Suppl. )   S18 - S20   2023

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    Language：Japanese   Publisher：看護理工学会  

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  • The嚥下エコー 誤嚥と残留物を可視化する嚥下エコーのこれまでと将来展望

    三浦 由佳, 玉井 奈緒, 松本 勝, 永田 みさ子, 須釜 淳子, 真田 弘美

    日本摂食・嚥下リハビリテーション学会雑誌   26 ( 3 )   S61 - S61   2022.12

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    Language：Japanese   Publisher：(一社)日本摂食嚥下リハビリテーション学会  

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  • 末梢静脈カテーテル留置のための穿刺部位選定におけるAIによるエコー画像読影サポート機能の効果

    阿部 麻里, 村山 陵子, 高橋 聡明, 松本 勝, 玉井 奈緒, 仲上 豪二朗, 真田 弘美

    日本看護科学学会学術集会講演集   42回   346 - 347   2022.12

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    Language：Japanese   Publisher：(公社)日本看護科学学会  

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  • 「生きる」を支える看護ケアのイノベーション 日常生活行動「食べる」を支える看護ケアイノベーション

    三浦 由佳, 玉井 奈緒, 松本 勝, 永田 みさ子, 須釜 淳子, 真田 弘美

    日本看護科学学会学術集会講演集   42回   123 - 123   2022.12

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    Language：Japanese   Publisher：(公社)日本看護科学学会  

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  • 摂食嚥下時の誤嚥・咽頭残留アセスメントに関する看護ケアガイドライン

    須釜 淳子, 石橋 みゆき, 大田 えりか, 鎌倉 やよい, 才藤 栄一, 真田 弘美, 中山 健夫, 野村 岳志, 山田 雅子, 仲上 豪二朗, 佐藤 直子, 柴田 斉子, 長谷 剛志, 深田 順子, 三鬼 達人, 有田 弥棋子, 浦井 珠恵, 大川 洋平, 北村 言, 臺 美佐子, 高橋 聡明, 玉井 奈緒, 飛田 伊都子, 野口 博史, 松本 勝, 三浦 由佳, 向井 加奈恵, 麦田 裕子, 吉田 美香子, 倉智 雅子, 白坂 誉子, 山根 由起子, 日本看護科学学会

    日本看護科学会誌   42   790 - 810   2022.12

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  • The嚥下エコー 誤嚥と残留物を可視化する嚥下エコーのこれまでと将来展望

    三浦 由佳, 玉井 奈緒, 松本 勝, 永田 みさ子, 須釜 淳子, 真田 弘美

    日本摂食・嚥下リハビリテーション学会雑誌   26 ( 3 )   S61 - S61   2022.12

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    Language：Japanese   Publisher：(一社)日本摂食嚥下リハビリテーション学会  

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  • Development and validation of an infant facial skin assessment tool: a prospective observational study

    Manami Matsubara, Megumi Haruna, Kaori Yonezawa, Moeri Yokoyama, Emi Tahara-Sasagawa, Naoko Hikita, Yoshie Nakamura, Yoko Mizuno, Hiromi Sanada, Nao Tamai, Masatoshi Abe, Kosuke Kashiwabara

    BMC Pediatrics   22 ( 1 )   2022.10

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    Publishing type：Research paper (scientific journal)   Publisher：Springer Science and Business Media LLC  

    Abstract

    Background

    Severe infant eczema on the face should be treated early because it may lead to allergic diseases in the future. However, caregivers find it difficult to assess. A visual tool for caregivers is needed to easily determine infants’ facial skin condition severity based on the tool’s scores. We developed an infant facial skin assessment tool (IFSAT) and evaluated its reliability and validity.

    Methods

    The IFSAT draft was developed based on results of a previous literature review and qualitative sketch. Panels including medical professionals and a caregiver checked the draft’s content and face validity, and the IFSAT was finalized. To test the IFSAT’s reliability and validity, caregivers and one-month-old infants were recruited. Two scoring methods were additionally created based on the relation between the items and cure period. The relationships between scores and cure period, and the ability to predict whether the infant needed medical treatment were examined by each scoring method. For the predictive validity, scores for infants requiring medical treatment and those for infants who did not were also compared. For the intra-examiner reliability analysis, two pediatricians rated the scores separately twice using photographs. Inter-rater reliabilities were analyzed among pediatricians, nurses, and caregivers.

    Results

    Altogether, 113 infant-caregiver pairs participated in the testing phase. Of the two scoring methods created (versions 1 and 2), pediatricians’ and caregivers’ scores using versions 1 and 2 were related to the cure period. These scores predict whether the infant needed medical treatment. We then selected version 2 based on the medical professionals’ opinions. The scores of caregivers of infants requiring medical treatment were higher than those of caregivers of infants not requiring treatment (p < 0.001). The intraclass correlation coefficient (ICC) of intra-examiner reliability was 0.87. The ICC of inter-rater reliabilities between pediatricians’ and caregivers’ scores and between nurses’ and caregivers’ scores were 0.66, and 0.66, respectively.

    Conclusions

    The proposed IFSAT may be used to assess whether infants need medical treatment and whether to extend the cure period. The tool’s reliability and validity were confirmed.

    DOI： 10.1186/s12887-022-03691-7

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    Other Link： https://link.springer.com/article/10.1186/s12887-022-03691-7/fulltext.html

  • Japanese clinical practice guidelines for aspiration and pharyngeal residual assessment during eating and swallowing for nursing care.

    Junko Sugama, Miyuki Ishibasi, Erika Ota, Yayoi Kamakura, Eiichi Saitoh, Hiromi Sanada, Takeo Nakayama, Takeshi Nomura, Masako Yamada, Gojiro Nakagami, Naoko Sato, Seiko Shibata, Takashi Hase, Junko Fukada, Tatsuto Miki, Mikiko Arita, Tamae Urai, Yohei Okawa, Aya Kitamura, Misako Dai, Toshiaki Takahashi, Nao Tamai, Itoko Tobita, Hiroshi Noguchi, Masaru Matsumoto, Yuka Miura, Kanae Mukai, Yuko Mugita, Mikako Yoshida, Masako Kurachi, Takako Shirasaka, Yukiko Yamane

    Japan journal of nursing science : JJNS   19 ( 4 )   e12496   2022.10

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    AIM: This clinical practice guideline aims to provide and recommend methods of assessing aspiration and pharyngeal residue during eating and swallowing and methods of selecting and implementing nursing care for adults to prevent the development of aspiration pneumonia through early and appropriate management of oropharyngeal dysphagia. METHODS: In April 2018, the Japan Academy of Nursing Science established the Supervisory Committee in Nursing Care Development/Standardization Committee to develop clinical practice guidelines for aspiration and pharyngeal residual assessment during eating and swallowing for nursing care. This clinical practice guideline was developed according to the Minds Manual for Guideline Development 2017, with the aim of providing a specific pathway for nurses to determine the policy for selecting management for oropharyngeal dysphagia based on research evidence and multifaceted factors including the balance of benefits and harms and patients' values. RESULTS: Based on the 10 clinical questions related to assessment by physical assessment, the Repetitive Saliva Swallowing Test, Modified Water Swallowing Test, Food Test, cervical auscultation, observation using an ultrasound diagnostic device, and an endoscope, 10 recommendations have been developed. Eight recommendations have been evaluated as the Grading of Recommendations Assessment, Development and Evaluation (GRADE) 2C, and the other two have been evaluated as no GRADE. CONCLUSION: The first reliable clinical practice guideline has been produced from an academic nursing organization that focuses on assessment for nursing care and incorporates the latest findings.

    DOI： 10.1111/jjns.12496

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  • 泌尿器科病棟看護師によるポータブルエコーを用いた排尿アセスメントと骨盤底筋訓練

    増田 稔, 脇田 早苗, 田中 香美, 鈴木 基文, 久米 春喜, 松本 勝, 玉井 奈緒, 真田 弘美

    日本老年泌尿器科学会誌   35 ( 1 )   74 - 74   2022.5

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  • ポータブルエコーを用いた排便アセスメントで臨床現場が変わる

    松本 勝, 玉井 奈緒, 三浦 由佳, 永田 みさ子, 紺家 千津子, 真田 弘美

    日本老年泌尿器科学会誌   35 ( 1 )   73 - 73   2022.5

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  • 泌尿器科病棟看護師によるポータブルエコーを用いた排尿アセスメントと骨盤底筋訓練

    増田 稔, 脇田 早苗, 田中 香美, 鈴木 基文, 久米 春喜, 松本 勝, 玉井 奈緒, 真田 弘美

    日本老年泌尿器科学会誌   35 ( 1 )   74 - 74   2022.5

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  • ポータブルエコーを用いた排便アセスメントで臨床現場が変わる

    松本 勝, 玉井 奈緒, 三浦 由佳, 永田 みさ子, 紺家 千津子, 真田 弘美

    日本老年泌尿器科学会誌   35 ( 1 )   73 - 73   2022.5

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  • チーム医療におけるPOCUS-多職種連携とPOCUS- 看護におけるエコーを用いた第6のフィジカルアセスメント 可視化

    松本 勝, 玉井 奈緒, 三浦 由佳, 永田 みさ子, 真田 弘美

    超音波医学   49 ( Suppl. )   S505 - S505   2022.4

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  • チーム医療におけるPOCUS-多職種連携とPOCUS- 看護におけるエコーを用いた第6のフィジカルアセスメント 可視化

    松本 勝, 玉井 奈緒, 三浦 由佳, 永田 みさ子, 真田 弘美

    超音波医学   49 ( Suppl. )   S505 - S505   2022.4

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  • Expert Consensus Document: Diagnosis for Chronic Constipation with Faecal Retention in the Rectum Using Ultrasonography. International journal

    Masaru Matsumoto, Noboru Misawa, Momoko Tsuda, Noriaki Manabe, Takaomi Kessoku, Nao Tamai, Atsuo Kawamoto, Junko Sugama, Hideko Tanaka, Mototsugu Kato, Ken Haruma, Hiromi Sanada, Atsushi Nakajima

    Diagnostics (Basel, Switzerland)   12 ( 2 )   2022.1

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    Chronic constipation is a common gastrointestinal disorder in older adults, and it is very important to manage chronic constipation. However, evaluating these subjective symptoms is extremely difficult in cases where patients are unable to express their symptoms because of a cognitive or physical impairment. Hence, it is necessary to observe the patient's colonic faecal retention using objective methods. Ultrasonography observation for colonic faecal retention is useful for diagnosing constipation and evaluating the effectiveness of treatment. Since there was no standard protocol for interpreting rectal ultrasonography findings, we developed an observation protocol through an expert consensus. We convened a group of experts in the diagnosis and evaluation of chronic constipation and ultrasonography to discuss and review the current literature on this matter. Together, they composed a succinct, evidence-based observation protocol for rectal faecal retention using ultrasonography. We created an observation protocol to enhance the quality and accuracy of diagnosis of chronic constipation, especially rectal constipation. This consensus statement is intended to serve as a guide for physicians, laboratory technicians and nurses who do not specialise in ultrasound or the diagnosis of chronic constipation.

    DOI： 10.3390/diagnostics12020300

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  • 在宅療養高齢者の慢性高張性脱水に関する予備的疫学調査(A pilot epidemiological study on chronic dehydration of older adults in home care setting)

    東村 志保, 玉井 奈緒, 仲上 豪二朗, 戸部 浩美, 真田 弘美

    看護理工学会誌   9   123 - 135   2022

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  • 【褥瘡とスキン-テアのケア】精神科病棟における褥瘡、スキン-テア

    玉井 奈緒, 木戸 芳史, 真田 弘美

    精神科看護   49 ( 1 )   004 - 011   2021.12

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  • 【褥瘡とスキン-テアのケア】精神科病棟における褥瘡、スキン-テア

    玉井 奈緒, 木戸 芳史, 真田 弘美

    精神科看護   49 ( 1 )   004 - 011   2021.12

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  • 看護エコーの可能性を診療看護師(NP)と考える エコーを用いたフィジカルアセスメントでケアが変わる!現場が変わる!

    玉井 奈緒, 松本 勝, 三浦 由佳, 真田 弘美

    日本NP学会誌   5 ( Suppl. )   95 - 95   2021.11

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  • 細胞障害性抗がん剤による手足症候群に対するビタミンB6の有効性のメタアナリシス

    下井 辰徳, 玉井 奈緒, 宇田川 涼子, 尾関 理恵, 齊藤 典充, 齋藤 昌孝, 齊藤 光江, 渡辺 隆紀, 清水 千佳子, 野澤 桂子

    日本癌治療学会学術集会抄録集   59回   P12 - 1   2021.10

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  • Development of an Automatic Ultrasound Image Classification System for Pressure Injury Based on Deep Learning

    Masaru Matsumoto, Mikihiko Karube, Gojiro Nakagami, Aya Kitamura, Nao Tamai, Yuka Miura, Atsuo Kawamoto, Masakazu Kurita, Tomomi Miyake, Chieko Hayashi, Akiko Kawasaki, Hiromi Sanada

    Applied Sciences   11 ( 17 )   7817 - 7817   2021.8

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    The classification of ultrasound (US) findings of pressure injury is important to select the appropriate treatment and care based on the state of the deep tissue, but it depends on the operator’s skill in image interpretation. Therefore, US for pressure injury is a procedure that can only be performed by a limited number of highly trained medical professionals. This study aimed to develop an automatic US image classification system for pressure injury based on deep learning that can be used by non-specialists who do not have a high skill in image interpretation. A total 787 training data were collected at two hospitals in Japan. The US images of pressure injuries were assessed using the deep learning-based classification tool according to the following visual evidence: unclear layer structure, cobblestone-like pattern, cloud-like pattern, and anechoic pattern. Thereafter, accuracy was assessed using two parameters: detection performance, and the value of the intersection over union (IoU) and DICE score. A total of 73 images were analyzed as test data. Of all 73 images with an unclear layer structure, 7 showed a cobblestone-like pattern, 14 showed a cloud-like pattern, and 15 showed an anechoic area. All four US findings showed a detection performance of 71.4–100%, with a mean value of 0.38–0.80 for IoU and 0.51–0.89 for the DICE score. The results show that US findings and deep learning-based classification can be used to detect deep tissue pressure injuries.

    DOI： 10.3390/app11177817

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  • Evaluation of a Point-of-Care Ultrasound Educational Program for Nurse Educators. International journal

    Masaru Matsumoto, Nao Tamai, Yuka Miura, Yohei Okawa, Mikako Yoshida, Yasuhiko Igawa, Gojiro Nakagami, Hiromi Sanada

    Journal of continuing education in nursing   52 ( 8 )   375 - 381   2021.8

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    BACKGROUND: The effectiveness of point-of-care ultrasound (POCUS) for nurses has been demonstrated; however, only a limited number of nurses have been trained to perform POCUS. This article reports on a POCUS train-the-trainer program for nurse educators that targets lower urinary track dysfunction. METHOD: Nurse educators (n = 38) were invited to participate in a POCUS train-the-trainer program, which comprised an e-learning module and a hands-on seminar. Acquisition of knowledge and skills were assessed after the module and seminar, respectively. RESULTS: Questions from the "Basic Knowledge of Ultrasonography" test were answered correctly at a rate of 93.0% (SD, 8.5%). Measured values of bladder urinary volume using ultrasonography were in close agreement with actual values. All of the participants indicated that the program covered the content necessary to use in practice. CONCLUSION: The POCUS train-the-trainer program equips nurse educators with the knowledge and skills needed for training nurses at their institutions. [J Contin Educ Nurs. 2021;52(8):375-381.].

    DOI： 10.3928/00220124-20210714-07

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  • 深層学習を用いた褥瘡部の超音波画像自動分類システムの開発

    松本 勝, 仲上 豪二朗, 北村 言, 玉井 奈緒, 栗田 昌和, 三宅 知美, 河崎 明子, 林 千恵子, 真田 弘美

    日本褥瘡学会誌   23 ( 3 )   267 - 267   2021.8

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  • 深層学習を用いた褥瘡部の超音波画像自動分類システムの開発

    松本 勝, 仲上 豪二朗, 北村 言, 玉井 奈緒, 栗田 昌和, 三宅 知美, 河崎 明子, 林 千恵子, 真田 弘美

    日本褥瘡学会誌   23 ( 3 )   267 - 267   2021.8

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  • Evaluation of bowel preparation before colonoscopy by ultrasonographic monitoring of colonic fecal retention(和訳中)

    Matsumoto Masaru, Fujioka Masayuki, Okada Toshihiko, Naka Yutaka, Amemiya Ayumi, Matsushima Erina, Tamai Nao, Miura Yuka, Nakagami Gojiro, Sanada Hiromi

    日本創傷・オストミー・失禁管理学会誌   25 ( 2 )   450 - 450   2021.7

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  • 訪問看護師によるエコーを用いた膀胱留置カテーテル挿入後の観察により観察時間の短縮につながった一例

    新関 こずえ, 小川 真里子, 松本 勝, 玉井 奈緒, 三浦 由佳, 東村 志保, 北村 言, 高橋 聡明, 仲上 豪二朗, 真田 弘美

    日本創傷・オストミー・失禁管理学会誌   25 ( 2 )   330 - 330   2021.7

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  • 訪問看護師によるエコーを用いた下行結腸の便貯留評価に基づく便秘への介入が自力排便につながった一症例

    新関 こずえ, 小川 真里子, 松本 勝, 玉井 奈緒, 三浦 由佳, 東村 志保, 北村 言, 高橋 聡明, 仲上 豪二朗, 真田 弘美

    日本創傷・オストミー・失禁管理学会誌   25 ( 2 )   330 - 330   2021.7

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  • エコーを用いた大腸便貯留観察により不要な坐剤投与が減少した中心静脈栄養を受ける寝たきり患者の一例

    皆月 美幸, 水谷 衣里, 山中 知子, 高田 千嘉, 松本 勝, 板橋 みずほ, 玉井 奈緒, 三浦 由佳, 真田 弘美

    日本創傷・オストミー・失禁管理学会誌   25 ( 2 )   329 - 329   2021.7

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  • 立位におけるエコーを用いた膀胱観察手技の標準化と膀胱内尿量推定式の検討

    中山 絵美子, 玉井 奈緒, 松本 勝, 三浦 由佳, 鈴木 基文, 野寄 修平, 板橋 みずほ, 真田 弘美

    日本創傷・オストミー・失禁管理学会誌   25 ( 2 )   252 - 252   2021.7

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  • エコーによる排泄アセスメントのための技術講習会オンライン化の試み

    中村 深雪, 保坂 明美, 松本 勝, 三浦 由佳, 玉井 奈緒, 仲上 豪二朗, 真田 弘美

    日本創傷・オストミー・失禁管理学会誌   25 ( 2 )   359 - 359   2021.7

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  • 泌尿器科病棟看護師によるポータブルエコーを用いた骨盤底筋トレーニング指導の実現可能性の検討

    増田 稔, 脇田 早苗, 鈴木 基文, 久米 春喜, 松本 勝, 玉井 奈緒, 真田 弘美

    日本創傷・オストミー・失禁管理学会誌   25 ( 2 )   354 - 354   2021.7

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  • 訪問看護師が撮影した直腸エコー動画に対するAIによる便貯留評価手法の考案

    松本 勝, 石橋 昂大, 北村 言, 玉井 奈緒, 三浦 由佳, 高橋 聡明, 東村 志保, 仲上 豪二朗, 真田 弘美

    日本創傷・オストミー・失禁管理学会誌   25 ( 2 )   335 - 335   2021.7

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  • 立位におけるエコーを用いた膀胱観察手技の標準化と膀胱内尿量推定式の検討

    中山 絵美子, 玉井 奈緒, 松本 勝, 三浦 由佳, 鈴木 基文, 野寄 修平, 板橋 みずほ, 真田 弘美

    日本創傷・オストミー・失禁管理学会誌   25 ( 2 )   252 - 252   2021.7

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  • 訪問看護師によるエコーを用いた下行結腸の便貯留評価に基づく便秘への介入が自力排便につながった一症例

    新関 こずえ, 小川 真里子, 松本 勝, 玉井 奈緒, 三浦 由佳, 東村 志保, 北村 言, 高橋 聡明, 仲上 豪二朗, 真田 弘美

    日本創傷・オストミー・失禁管理学会誌   25 ( 2 )   330 - 330   2021.7

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  • エコーを用いた大腸便貯留観察により不要な坐剤投与が減少した中心静脈栄養を受ける寝たきり患者の一例

    皆月 美幸, 水谷 衣里, 山中 知子, 高田 千嘉, 松本 勝, 板橋 みずほ, 玉井 奈緒, 三浦 由佳, 真田 弘美

    日本創傷・オストミー・失禁管理学会誌   25 ( 2 )   329 - 329   2021.7

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  • 訪問看護におけるエコーを用いた膀胱の可視化により残尿の原因のアセスメントとケアにつながった一例

    保坂 明美, 小路 郁美, 高橋 明美, 工藤 陽子, 藤森 昌子, 清水 鉄也, 松本 勝, 三浦 由佳, 玉井 奈緒, 真田 弘美

    日本創傷・オストミー・失禁管理学会誌   25 ( 2 )   328 - 328   2021.7

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  • 訪問看護師のエコーを用いた水腎症評価により早期介入と家族の負担軽減につながった18トリソミー児の一例

    保坂 明美, 中島 美佳, 松本 勝, 三浦 由佳, 北村 言, 玉井 奈緒, 高橋 聡明, 東村 志保, 仲上 豪二朗, 真田 弘美

    日本創傷・オストミー・失禁管理学会誌   25 ( 2 )   328 - 328   2021.7

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  • エコーによる排泄アセスメントのための技術講習会オンライン化の試み

    中村 深雪, 保坂 明美, 松本 勝, 三浦 由佳, 玉井 奈緒, 仲上 豪二朗, 真田 弘美

    日本創傷・オストミー・失禁管理学会誌   25 ( 2 )   359 - 359   2021.7

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  • 泌尿器科病棟看護師によるポータブルエコーを用いた骨盤底筋トレーニング指導の実現可能性の検討

    増田 稔, 脇田 早苗, 鈴木 基文, 久米 春喜, 松本 勝, 玉井 奈緒, 真田 弘美

    日本創傷・オストミー・失禁管理学会誌   25 ( 2 )   354 - 354   2021.7

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  • 訪問看護師が撮影した直腸エコー動画に対するAIによる便貯留評価手法の考案

    松本 勝, 石橋 昂大, 北村 言, 玉井 奈緒, 三浦 由佳, 高橋 聡明, 東村 志保, 仲上 豪二朗, 真田 弘美

    日本創傷・オストミー・失禁管理学会誌   25 ( 2 )   335 - 335   2021.7

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  • 訪問看護師によるエコーを用いた膀胱留置カテーテル挿入後の観察により観察時間の短縮につながった一例

    新関 こずえ, 小川 真里子, 松本 勝, 玉井 奈緒, 三浦 由佳, 東村 志保, 北村 言, 高橋 聡明, 仲上 豪二朗, 真田 弘美

    日本創傷・オストミー・失禁管理学会誌   25 ( 2 )   330 - 330   2021.7

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  • Extraction of outcome candidates to evaluate the effects of nurses who have completed advanced nursing training(和訳中)

    Miura Yuka, Nakagami Gojiro, Yoshida Mikako, Higashimura Shiho, Mugita Yuko, Yoshikawa Tomohiro, Murayama Ryoko, Oe Makoto, Tamai Nao, Matsumoto Masaru, Dai Misako, Kitamura Aya, Takahashi Toshiaki, Abe Mari, Sanada Hiromi

    日本創傷・オストミー・失禁管理学会誌   25 ( 2 )   457 - 457   2021.7

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  • Urine biomarkers for lower urinary tract infections among diaper-wearing community-dwelling elderly individuals with cognitive impairments: A scoping review(和訳中)

    Itabashi Mizuho, Haba Daijiro, Tamai Nao, Miura Yuka, Nitta Shiori, Minematsu Takeo, Matsumoto Masaru, Nakagami Gojiro, Weller Carolina, Sanada Hiromi

    日本創傷・オストミー・失禁管理学会誌   25 ( 2 )   449 - 449   2021.7

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  • Evaluation of bladder debris using ultrasound devices in hospitalized and community-dwelling elderly individuals(和訳中)

    Tamai Nao, Matsumoto Masaru, Miura Yuka, Nakayama Emiko, Itabashi Mizuho, Takada Chika, Yamanaka Tomoko, Minazuki Miyuki, Mizutani Eri, Sanada Hiromi

    日本創傷・オストミー・失禁管理学会誌   25 ( 2 )   449 - 449   2021.7

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  • Accuracy of ultrasonic estimation of bladder urine volume in different body positions(和訳中)

    Nakayama Emiko, Tamai Nao, Matsumoto Masaru, Miura Yuka, Sanada Hiromi

    日本創傷・オストミー・失禁管理学会誌   25 ( 2 )   447 - 447   2021.7

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  • 訪問看護におけるエコーを用いた膀胱の可視化により残尿の原因のアセスメントとケアにつながった一例

    保坂 明美, 小路 郁美, 高橋 明美, 工藤 陽子, 藤森 昌子, 清水 鉄也, 松本 勝, 三浦 由佳, 玉井 奈緒, 真田 弘美

    日本創傷・オストミー・失禁管理学会誌   25 ( 2 )   328 - 328   2021.7

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  • 訪問看護師のエコーを用いた水腎症評価により早期介入と家族の負担軽減につながった18トリソミー児の一例

    保坂 明美, 中島 美佳, 松本 勝, 三浦 由佳, 北村 言, 玉井 奈緒, 高橋 聡明, 東村 志保, 仲上 豪二朗, 真田 弘美

    日本創傷・オストミー・失禁管理学会誌   25 ( 2 )   328 - 328   2021.7

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  • 【褥瘡 UPDATE エキスパートのための最新情報と栄養療法】(Part 3)褥瘡予測・予防・治療 アドバンスト編 スキン-テアの予防と治療・ケア

    玉井 奈緒

    臨床栄養   138 ( 6 )   895 - 900   2021.5

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  • Polymorphism analysis of candidate risk genes for pressure injuries in older Japanese patients: A cross-sectional study at a long-term care hospital. International journal

    Toshihiro Tsukatani, Takeo Minematsu, Misako Dai, Nao Tamai, Gojiro Nakagami, Junko Sugama, Chika Takada, Hiromi Sanada

    Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society   29 ( 5 )   741 - 751   2021.4

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    Advances in patient care for pressure injuries (PIs) have reduced the prevalence of PIs in Japan, although not in recent years. Several single-nucleotide polymorphisms (SNPs) have been identified in genes potentially associated with PIs. However, individual variance among PI risks require targeted investigations that may lead to the identification of PI susceptibilities or preventive care options that directly influence PI development pathways. This cross-sectional study examined the association between PIs and SNPs in genes related to tissue tolerance in patients in a long-term care hospital in Japan. A total of 178 participants (130 control, 20 with superficial PI history, and 28 with deep PI history) were enrolled in this study of eight SNPs in hypoxia inducible factor 1 subunit alpha (HIF1A), vascular endothelial growth factor C (VEGFC), heat shock protein 90 alpha family class A member 1 (HSP90AA1), myostatin (MSTN), and vitamin D receptor (VDR). The primary outcome was a history of superficial and deep PIs in the last 6 months. SNPs were examined by real-time polymerase chain reaction, followed by multivariate logistic regression analyses of the associations between the SNPs and PI history. The results showed a significant association between VEGFC rs1485766 and the history of superficial PIs (odds ratio = 2.95; 95% confidence interval = 1.07-8.11; p = 0.04). Stratified analysis using the Braden Scale (≤14) indicated a significant association between HIF1A rs11549465 and deep PIs (p = 0.04). Our study demonstrated that VEGFC rs1485766 and HIF1A rs11549465 were associated with superficial and deep PI susceptibilities, respectively.

    DOI： 10.1111/wrr.12912

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  • 【DTI・クリティカルコロナイゼーションを基礎から学ぶ!「DESIGN-R2020」を活用した褥瘡ケア】(Part 3)事例にみる「DESIGN-R2020」を活用した褥瘡ケア 車いすアスリートに発生したDTI疑いのアセスメントとケア

    臺 美佐子, 玉井 奈緒

    看護技術   67 ( 4 )   349 - 354   2021.4

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  • AI搭載ワイヤレス超音波診断装置を用いた排尿ケアの実施による看護業務改善効果

    脇田 早苗, 増田 稔, 鈴木 基文, 秋山 佳之, 佐藤 悠佑, 久米 春喜, 玉井 奈緒, 松本 勝, 真田 弘美

    日本老年泌尿器科学会誌   34 ( 1 )   134 - 134   2021.4

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  • 【病態を可視化しケアにつなぐ!看護師が実践するエコーを用いたケア】(Part 2)事例で学ぶ 看護師が実践するエコーを用いたケア 超音波検査によりDTIを発見し、ケアした事例

    玉井 奈緒

    看護技術   67 ( 4 )   374 - 379   2021.4

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  • 【病態を可視化しケアにつなぐ!看護師が実践するエコーを用いたケア】(Part 1)エコーを利用した看護アセスメントの現状

    玉井 奈緒, 真田 弘美

    看護技術   67 ( 4 )   372 - 373   2021.4

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  • AI搭載ワイヤレス超音波診断装置を用いた排尿ケアの実施による看護業務改善効果

    脇田 早苗, 増田 稔, 鈴木 基文, 秋山 佳之, 佐藤 悠佑, 久米 春喜, 玉井 奈緒, 松本 勝, 真田 弘美

    日本老年泌尿器科学会誌   34 ( 1 )   134 - 134   2021.4

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  • 【病態を可視化しケアにつなぐ!看護師が実践するエコーを用いたケア】(Part 2)事例で学ぶ 看護師が実践するエコーを用いたケア 摂食嚥下障害のケアの事例

    保坂 明美, 三浦 由佳, 玉井 奈緒

    看護技術   67 ( 4 )   386 - 391   2021.4

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  • Diagnostic accuracy of ultrasound examination in detecting aspiration and pharyngeal residue in patients with dysphagia: A systematic review and meta-analysis.

    Yuka Miura, Nao Tamai, Aya Kitamura, Mikako Yoshida, Toshiaki Takahashi, Yuko Mugita, Itoko Tobita, Mikiko Arita, Tamae Urai, Misako Dai, Hiroshi Noguchi, Masaru Matsumoto, Kanae Mukai, Gojiro Nakagami, Erika Ota, Junko Sugama, Hiromi Sanada

    Japan journal of nursing science : JJNS   18 ( 2 )   e12396   2021.4

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    AIM: To estimate diagnostic accuracy of ultrasonography for detecting aspiration and pharyngeal residue in patients with dysphagia. METHODS: A systematic search was conducted in MEDLINE (via PubMed), CINAHL, EMBASE, Ichushi-Web, and Cochrane Library databases to identify articles that showed diagnostic accuracy of ultrasonography for detecting aspiration and residue published in English and Japanese until August 2019. Cross-sectional studies, case-control studies, and cohort studies were included. The diagnostic accuracy results were extracted and the pooled estimated sensitivity and specificity were calculated. The risk of bias of the studies was assessed using the Revised Tool for the Quality Assessment of Diagnostic Accuracy Studies 2. The certainty of the evidence was assessed using the Grades of Recommendation Assessment, Development, and Evaluation methodology. RESULTS: Five studies were included in this review. The pooled estimated sensitivity and specificity for detecting aspiration were 0.82 (95% CI: 0.72-0.89) and 0.87 (95% CI: 0.81-0.92), respectively. One study was included that evaluated ultrasound assessments of pharyngeal residue. The sensitivity and specificity were 0.62 (95% CI: 0.32-0.86) and 0.67 (95% CI: 0.22-0.96), respectively. The certainty of the evidence was low and very low for the diagnostic accuracy of aspiration and pharyngeal residue, respectively. CONCLUSION: Ultrasound is a non-invasive method with good sensitivity and specificity in detecting aspiration as well as reference standards. While risk of bias and small number of studies limited the strength of this systematic review, our results suggested that ultrasound examination was useful as a bedside screening tool for detecting aspiration.

    DOI： 10.1111/jjns.12396

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  • Risk scoring tool for forearm skin tears in Japanese older adults: A prospective cohort study. International journal

    Takeo Minematsu, Misako Dai, Nao Tamai, Gojiro Nakagami, Tamae Urai, Ayano Nakai, Shiori Nitta, Yukie Kataoka, Weijie Kuang, Mao Kunimitsu, Toshihiro Tsukatani, Hajime Oyama, Tomohiro Yoshikawa, Chika Takada, Miyoko Kuwata, Hiromi Sanada

    Journal of tissue viability   30 ( 2 )   155 - 160   2021.3

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    [Aim] Because painful skin tears frequently occur in older patients, the prevention of skin tears is fundamental to improve their quality of life. However, a risk assessment tool for skin tears has not been established yet in Japan. Therefore, we aimed to propose a risk scoring tool for skin tears in Japanese older adult. [Methods] We conducted a prospective cohort study with 6-month follow-up in two long-term care hospitals in Japan. A total of 257 inpatients were recruited. Patient and skin characteristics were collected at baseline, and the occurrence of forearm skin tears were examined during follow-up. To develop a risk scoring tool, we identified risk factors, and converted their coefficients estimated in the multiple logistic regression analysis into simplified scores. The predictive accuracy of the total score was evaluated. [Results] Of 244 participants, 29 developed forearm skin tears during the follow-up period, a cumulative incidence of 13.5%. Senile purpura, pseudoscar, contracture, and dry skin were identified as risk factors for skin tears. Their weighted scores were 6, 4, 5, and 6, respectively. The area under the receiver operating characteristic curve of the total score was 0.806. At a cut-off score of 12, the sensitivity was 0.86, and the specificity was 0.67. [Conclusion] Our forearm skin tear risk scoring tool showed high accuracy, whereas specificity was low. This tool can contribute to prevent forearm skin tears in Japanese older adults.

    DOI： 10.1016/j.jtv.2021.02.010

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  • 【非がん疾患に対する緩和ケア】症状アセスメントとマネジメント 褥瘡,創傷

    玉井 奈緒, 真田 弘美

    内科   127 ( 2 )   199 - 203   2021.2

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  • Effects of improved hypoallergenic fabrics in medical wigs in patients with breast cancer with chemotherapy-induced alopecia: a randomised clinical trial. International journal

    Nao Tamai, Takeo Minematsu, Mari Ikeda, Yuko Mugita, Hiromi Sanada

    BMJ supportive & palliative care   2021.1

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    PURPOSE: Chemotherapy causes changes in appearance in patients with cancer. Therefore, to have a normal life, it is necessary for patients to wear a wig. However, wearing a wig may strain an already sensitive scalp during chemotherapy. This study aimed to assess the effects of a hypoallergenic medical wig in breast cancer patients with chemotherapy-induced alopecia (CIA). METHODS: A randomised, single-blind, controlled study was conducted from January 2015 to July 2017 in Tokyo, Japan. Women with non-metastatic breast cancers were enrolled. Participants were provided a hypoallergenic medical wig or a traditional medical wig. The primary endpoint was incidence of scalp dermatitis, including erythema, rash and erosion. The secondary endpoints were incidence of scalp symptoms, alterations in scalp barrier functions and quality of life (QOL). Patients were followed at the start of the first chemotherapy administration and at 13th week. RESULTS: Fifty-nine women were included in the analysis. At 13th week, the incidence of erythema was 44.8% among patients in the intervention group and 86.7% among patients in the control group, in the intention-to-treat analysis (p<0.01). The incidence of erosion tended to decrease in the intervention group at the 13th week (p=0.09). The incidence of scalp symptoms, alterations in scalp barrier functions and QOL were not significantly different between the groups. CONCLUSIONS: The incidence of dermatitis, including erythema, rash and erosion, decreased when wearing the new hypoallergenic medical wig. The gentle hypoallergenic medical wig is useful in improving erythema in cancer patients with CIA.Trial registration number UMIN000021289.

    DOI： 10.1136/bmjspcare-2020-002309

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  • Development of AI-based fecal retention assessment method for rectal ultrasonography videos taken by home-visit nurses

    Matsumoto Masaru, Ishibashi Kousuke, Kitamura Aya, Tamai Nao, Miura Yuka, Takahashi Toshiaki, Higashimura Shiho, Nakagami Gojiro, Sanada Hiromi

    Journal of Nursing Science and Engineering   9   34 - 46   2021

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    Language：Japanese   Publisher：The Society for Nursing Science and Engineering  

    The purpose of this study was to develop a method for more accurate evaluation of fecal retention by an artificial intelligence interpretation support application that determines and displays in red extraction area the presence of fecal retention for rectal ultrasonographic videos taken by home-visiting nurses. In this study, static images were output from rectal ultrasonographic videos taken from medical records of one home-care nursing station. For each static image, the ultrasound expert and the application judged the presence of fecal retention based on half-moon or crescent-shaped hyperechoic findings as extraction area. This study focused on images that were false-positive results for the application when the ultrasound expert&rsquo;s answer was correct. Extracted regions with a depth of less than 50 mm and a longitudinal diameter of less than 14.5 mm were excluded to distinguish them from stool and gas retentions outside the rectum. As a result, the sensitivity was 81.1%, specificity 87.8%, and correct rate 83.7%. A method of adjusting the depth and long diameter of the extraction area was developed as a means for improving the judgement accuracy of the application.

    DOI： 10.24462/jnse.9.0_34

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  • Evaluation of bowel preparation before colonoscopy by ultrasonographic monitoring of colonic fecal retention: a case series. International journal

    Masaru Matsumoto, Masayuki Fujioka, Toshihiko Okada, Yutaka Naka, Ayumi Amemiya, Erina Matsushima, Nao Tamai, Yuka Miura, Gojiro Nakagami, Hiromi Sanada

    Medical ultrasonography   23 ( 2 )   147 - 152   2020.12

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    AIMS: While bowel preparation for colonoscopy is the key to successful examination, taking laxatives and showing stools to others causes both physical and mental distress to the patient. Thus, an alternative method to evaluation bowel preparation is necessary. In the current study, we studied the colonic fecal retention by ultrasonography (US) and examined the US finding which reflected completion of BP. MATERIAL AND METHODS: The subjects were outpatients who underwent colonoscopy. This report summarizes the ultrasonographic images of patients who underwent multiple US examinations for all five sites of the colon just before, during, and immediately after bowel preparation. According to the standard protocol, the patients took 2 L of polyethylene glycol-ascorbic acid as a laxative, which was discontinued when the nurse visually judged the stool to be clear. RESULTS: Seven patients in their 50s-80s, none of whom were unable to complete a colonoscopy due to residual feces were included in study. Following bowel preparation, the US images showed anechoic areas with haustration in four or all five areas of the colon. Three of the seven patients received low-dose laxatives (1.1-1.2 L); all three had watery stools in three or more colon areas and none of them were constipated at the time of taking 1 L of laxatives. CONCLUSIONS: Completion of bowel preparation can be assessed by the observation of anechoic areas with haustration in multiple colonic sites by ultrasonography.

    DOI： 10.11152/mu-2792

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  • 長期療養型病院における看護師のためのスキン-テア予防教育の効果 前後比較研究(Effect of an education program on the prevention of skin tears for nurses in a Japanese long-term care hospital: A pre-post study)

    玉井 奈緒, 桑田 美代子, 浦井 珠恵, 後 智子, 山下 由香, 峰松 健夫, 臺 美佐子, 中井 彩乃, こう 偉杰, 片岡 友紀恵, 新田 汐里, 野呂 修平, 真田 弘美

    日本創傷・オストミー・失禁管理学会誌   24 ( 4 )   379 - 387   2020.12

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  • 創傷アセスメント技術 エコーを用いた褥瘡部のアセスメント

    松本 勝, 仲上 豪二朗, 北村 言, 玉井 奈緒, 真田 弘美

    日本創傷治癒学会プログラム・抄録集   50回   62 - 62   2020.11

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  • 創傷アセスメント技術 エコーを用いた褥瘡部のアセスメント

    松本 勝, 仲上 豪二朗, 北村 言, 玉井 奈緒, 真田 弘美

    日本創傷治癒学会プログラム・抄録集   50回   62 - 62   2020.11

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  • The relationship between skin ultrasound images and muscle damage using skin blotting in wheelchair basketball athletes International journal

    Nao Tamai, Takeo Minematsu, Tomonori Maeda, Koichi Yabunaka, Hiromi Sanada

    SPINAL CORD   58 ( 9 )   1022 - 1029   2020.9

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    DOI： 10.1038/s41393-020-0442-6

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  • Effects of the appearance care program for breast cancer patients receiving chemotherapy: A mixed method study. International journal

    Mari Ikeda, Nao Tamai, Hisako Kanai, Misato Osaka, Kazuko Kondo, Takako Yamazaki, Hiromi Sanada, Kiyoko Kamibeppu

    Cancer reports (Hoboken, N.J.)   3 ( 3 )   e1242   2020.6

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    BACKGROUND: Treatment of breast cancer entails surgery, often followed by chemotherapy. Alopecia is a major, intractable side effect with potentially profound impacts on appearance. We developed a nurse-facilitated program targeting appearance-related symptoms. AIMS: This study explored the effects of the appearance care program on quality of life (QOL). The program was delivered across three sessions, each involving personal reflections on appearance concerns, short lectures on skincare and makeover techniques, and small group discussions. METHOD AND RESULTS: Seventy-two women who attended the appearance care program were invited to participate. We employed a mixed-method design combining quantitative and qualitative methods. QOL instruments were used to measure effects of the program at the first and final sessions and at a one-month follow-up. The qualitative data were collected as open-ended notes regarding participants' perception of the program at the final session and at a one-month follow-up. Fifty-seven women completed all three sessions. Of them, 55 participated in this study. Their mean age was 46.4 years; 39 (70.9%) had partners, and 34 (61.8%) had children. Most participants experienced hair loss at one-month post-program; however, cancer-specific QOL improved after attending the program. Patients' experience of fatigue and weakness may explain observations of decreased physical well-being. Emotional well-being continued to increase 1 month following the program, while social and functional well-being was consistent. Participants felt empowered by the information on skincare and cosmetic techniques and valued the intimate support from the group members facing similar circumstances. CONCLUSIONS: This study showed that the appearance care program increased or maintained the well-being of participants. Findings suggest the appearance care program which promoted group sharing experiences empowered participants and may have enhanced their coping strategies.

    DOI： 10.1002/cnr2.1242

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  • Effects of skin care education for care staff at elderly care facilities on skin conditions of the residents. Reviewed International journal

    Yuichiro Tsunemi, Gojiro Nakagami, Kimie Takehara, Nao Tamai, Aya Kitamura, Yuko Mugita, Makoto Oe, Momoyo Kishida, Hiromi Sanada

    The Journal of dermatology   47 ( 4 )   327 - 333   2020.4

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    Asteatosis is common in elderly people due to a decrease in the moisture content of the epidermal stratum corneum through a loss of skin barrier function caused by aging. Because itching often accompanies asteatosis, this condition may cause a decrease in quality of life. Care staff in elderly care facilities have many opportunities to provide care for residents. In this study, we examined how educational training on skin care changed the thoughts and actions of care staff in these facilities and how these changes impacted the skin conditions of residents. The subjects for the training were all care staff in facilities because these staff work most closely with facility residents. We performed skin care training for the subjects and investigated changes in the skin conditions of the residents before and after the training. The training promoted the understanding of skin care among the care staff and improved the skin symptoms of residents with asteatosis. However, there were no changes in the severity of itchiness based on a verbal rating scale and in interviews of residents. This study showed that skin care training for the care staff in facilities is effective to improve skin conditions of residents. In addition, it was suggested that a full grasp of the residents' skin symptoms based upon an interview on itching alone was difficult, and thus there is a need to observe skin conditions directly.

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  • エコーを用いた膀胱内尿量測定技術習得のための看護師対象教育プログラムの効果 評定者間信頼性の検証 Reviewed

    玉井 奈緒, 三浦 由佳, 松本 勝, 真田 弘美

    日本ストーマ・排泄リハビリテーション学会誌   36 ( 1 )   216 - 216   2020.1

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  • Implementing Appearance-Care Research for Breast Cancer Patient into Routine Clinical Practice

    Mari Ikeda, Hisako Kanai, Misato Osaka, Nao Tamai, Yukie Takemura, Hiromi Sanada

    Open Journal of Nursing   10 ( 03 )   308 - 319   2020

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    Publishing type：Research paper (scientific journal)   Publisher：Scientific Research Publishing, Inc.  

    DOI： 10.4236/ojn.2020.103021

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  • 防ぎきれない褥瘡を考える 長期療養型病院におけるKennedy Terminal Ulcerの発生とその特徴

    玉井 奈緒, 高橋 聡明, 真田 弘美

    日本創傷治癒学会プログラム・抄録集   49回   60 - 60   2019.12

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  • 医用画像認識技術を用いた超音波画像における膀胱内尿量計測支援ツールの開発と評価 Reviewed

    松本 勝, 仲上 豪二朗, 蔦岡 拓也, 半田 真弓, 吉田 美香子, 玉井 奈緒, 三浦 由佳, 真田 弘美

    日本看護科学学会学術集会講演集   39回   [O5 - 04]   2019.11

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  • エコーを用いた排尿管理教育プログラム履修後の膀胱像の信頼性 看護師1名の達成度の報告 Reviewed

    玉井 奈緒, 三浦 由佳, 松本 勝, 高田 千嘉, 真田 弘美

    日本老年泌尿器科学会誌   32 ( 2 )   46 - 51   2019.11

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  • ラテラルフローイムノクロマトグラフィーを応用したスキンブロッティング試料の簡易染色システムの開発 Reviewed

    峰松 健夫, 臺 美佐子, 玉井 奈緒, 仲上 豪二朗, 真田 弘美

    日本看護科学学会学術集会講演集   39回   [O6 - 04]   2019.11

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  • Pattern detection from seating pressure distribution during wheelchair motion using deep embedded clustering. Reviewed International journal

    Hiroshi Noguchi, Tomonori Maeda, Nao Tamai, Takeo Minematsu, Hiromi Sanada, Taketoshi Mori

    Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference   2019   908 - 911   2019.7

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    DOI： 10.1109/EMBC.2019.8856751

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  • Prediction of healing in Category I pressure ulcers by skin blotting with plasminogen activator inhibitor 1, interleukin-1α, vascular endothelial growth factor C, and heat shock protein 90α: A pilot study. International journal

    Ayano Nakai, Takeo Minematsu, Nao Tamai, Junko Sugama, Tamae Urai, Hiromi Sanada

    Journal of tissue viability   28 ( 2 )   87 - 93   2019.5

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    The prevention of progression of Category I pressure ulcers (PUs) to Category II or higher is important, as Category II or higher PUs are open wounds and have a higher infection risk. Prognosis prediction of Category I PUs is necessary to provide successful intensive care for PUs with impaired healing. We focused on skin blotting using plasminogen activator inhibitor 1 (PAI1), interleukin-1α (IL-1α), vascular endothelial growth factor C (VEGF-C), and heat shock protein 90α (HSP90α). This pilot study was conducted at long-term-care and general hospitals to examine the applicability of DESIGN-R and thermography; the feasibility of skin blotting technique; the biomarker candidates, PAI1, IL-1α, VEGF-C, and HSP90α; and sample size for prognosis prediction for Category I PUs. Patients aged >65 years underwent skin blotting, scoring for DESIGN-R, and took thermography images of their Category I PU site. Albumin signals were not detected in one out of three participants. PAI1, IL-1α, VEGF-C, and HSP90α were detected in 19 participants, among whom 11 participants could be followed up after one week. There was no difference in DESIGN-R score and skin surface temperature between normal and impaired healing groups, and the sample size was calculated as 16. In conclusion, the feasibility of skin blotting was confirmed. PAI1, IL-1α, VEGF-C, and HSP90α could be biomarker candidates for prognosis prediction for Category I PU and the combination of VEGF-C and HSP90α could be associated with the prognosis of Category I PU. We need to investigate 842 patients in a future study.

    DOI： 10.1016/j.jtv.2019.02.002

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  • A multicenter survey of temporal changes in chemotherapy-induced hair loss in breast cancer patients International journal

    Takanori Watanabe, Hiroshi Yagata, Mitsue Saito, Hiroko Okada, Tamiko Yajima, Nao Tamai, Yuko Yoshida, Tomoko Takayama, Hirohisa Imai, Keiko Nozawa, Takafumi Sangai, Akiyo Yoshimura, Yoshie Hasegawa, Takuhiro Yamaguchi, Kojiro Shimozuma, Yasuo Ohashi

    PLOS ONE   14 ( 1 )   e0208118   2019.1

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    DOI： 10.1371/journal.pone.0208118

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  • Fecal Distribution Changes Using Colorectal Ultrasonography in Older People with Physical and Cognitive Impairment Living in Long-Term Care Facilities: A Longitudinal Observational Study. Reviewed International journal

    Shiho Tanaka, Koichi Yabunaka, Masaru Matsumoto, Nao Tamai, Hiroshi Noguchi, Mikako Yoshida, Gojiro Nakagami, Junko Sugama, Hiromi Sanada

    Healthcare (Basel, Switzerland)   6 ( 2 )   2018.5

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    Nurses encounter difficulties evaluating constipation in elderly people with physical and cognitive impairment. Transabdominal ultrasonography (US) has been used to evaluate fecal impaction or fecal quality. However, it is unclear whether colorectal US can evaluate constipation symptoms in older people. Using colorectal US, we continuously observed the elderly and clarified the relationship between patterns of fecal distribution changes and constipation symptoms in older people with physical and cognitive impairment at long-term care facilities. This study included patients aged ≥65 years with oral intake. US was performed once a day until the next defecation, and fecal hardness was assessed. US images were extracted and categorized. Then, patterns of fecal distribution changes in the colorectum were classified. Multiple logistic regression analysis was performed to examine related factors associated with a constipation pattern. Among 101 patients, US images of 95 patients were analyzed. In 74.4% of the patients, US showed continuation of reflection with acoustic shadow in the rectum, which was significantly associated with defecation on the bed. Of the patients with a continuous crescent-shaped reflection pattern (R3), 92.9% had hard stool. R3 was found to be significantly associated with a Mini-Mental State Examination score of ≤10. In most of the patients, US detected a continuation of reflection with acoustic shadow in rectal patterns, indicating fecal retention in the rectum. Point-of-care US can be used by nurses to visualize rectal fecal retention as constipation patterns in the older people with physical and cognitive impairment at long-term care facilities.

    DOI： 10.3390/healthcare6020055

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  • 学習障害をもつ極低出生体重児の視覚認知機能

    福井 美保, 島川 修一, 畑中 マリ, 水田 めくみ, 栗本 奈緒子, 竹下 盛, 三浦 朋子, 奥村 智人, 中西 誠, 若宮 英司, 玉井 浩

    脳と発達   50 ( Suppl. )   S428 - S428   2018.5

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  • カテゴリーI褥瘡のリンパ管新生マーカー、血管内皮増殖因子Cと併用したスキンブロッティングによる治癒の予測 予備的研究(Prediction of healing in Category I pressure ulcers by skin blotting with a lymphangiogenesis marker, vascular endothelial growth factor C: A pilot study)

    Nakai Ayano, Minematsu Takeo, Tamai Nao, Sugama Junko, Yabunaka Koichi, Urai Tamae, Tabata Keiko, Sanada Hiromi

    日本創傷・オストミー・失禁管理学会誌   22 ( 2 )   168 - 168   2018.5

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  • 静脈性下腿潰瘍の滲出液中の神経成長因子濃度は赤外線サーモグラフィで捉えた炎症に関連する(Nerve growth factor in exudate from venous leg ulcers is associated with inflammation along with temperature increase assessed by infrared thermography)

    後藤 大地, 仲上 豪二朗, 玉井 奈緒, 北村 言, 内藤 亜由美, 広川 雅之, 下川 千佐子, 真田 弘美

    日本創傷・オストミー・失禁管理学会誌   20 ( 3 )   310 - 318   2016.10

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  • The relationship between malignant wound status and pain in breast cancer patients Reviewed International journal

    Nao Tamai, Yuko Mugita, Mari Ikeda, Hiromi Sanada

    EUROPEAN JOURNAL OF ONCOLOGY NURSING   24   8 - 12   2016.10

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    DOI： 10.1016/j.ejon.2016.05.004

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  • 体圧分布に応じた独立エアセル制御機能を有するエアマットレスの開発と評価(Development and assessment of air mattress with independent air cell pressure control responsive to interface pressure distribution) Reviewed

    堀 紀子, 玉井 奈緒, 野口 博史, 仲上 豪二朗, 須釜 淳子, 森 武俊, 真田 弘美

    日本創傷・オストミー・失禁管理学会誌   20 ( 3 )   300 - 309   2016.10

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  • Exploring the prevalence of skin tears and skin properties related to skin tears in elderly patients at a long-term medical facility in Japan. Reviewed International journal

    Yuiko Koyano, Gojiro Nakagami, Shinji Iizaka, Takeo Minematsu, Hiroshi Noguchi, Nao Tamai, Yuko Mugita, Aya Kitamura, Keiko Tabata, Masatoshi Abe, Ryoko Murayama, Junko Sugama, Hiromi Sanada

    International wound journal   13 ( 2 )   189 - 97   2016.4

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    The identification of appropriate skin tear prevention guidelines for the elderly requires clinicians to focus on local risk factors such as structural alterations of the epidermis and dermis related to skin tears. The aim of this cross-sectional study is to explore the prevalence of skin tears and to explore skin properties related to skin tears in elderly Japanese patients at a long-term medical facility. After doing the prevalence study, 18 participants with skin tears and 18 without were recruited and an evaluation of their skin properties using 20-MHz ultrasonography, skin blotting and also Corneometer CM-825, Skin-pH-meterPH905, VapoMeter, Moisture Meter-D and CutometerMPA580 was undertaken. A total of 410 patients were examined, the median age was 87 years and 73·2% were women. The prevalence of skin tears was 3·9%, and 50% of skin tears occurred on the dorsal forearm. The changes in skin properties associated with skin tears included increased low-echogenic pixels (LEP) by 20-MHz ultrasonography, decreased type IV collagen and matrix metalloproteinase-2, and increased tumour necrosis factor-α by skin blotting. In conclusion, this study suggests that increased dermal LEP, including solar elastosis, may represent a risk factor for skin tears; this indicates that skin tear risk factors might not only represent chronological ageing but also photoageing.

    DOI： 10.1111/iwj.12251

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  • Association Between Components of Exudates and Periwound Moisture-Associated Dermatitis in Breast Cancer Patients With Malignant Fungating Wounds Reviewed International journal

    Nao Tamai, Tomoko Akase, Takeo Minematsu, Kyohei Higashi, Toshihiko Toida, Kazuei Igarashi, Hiromi Sanada

    BIOLOGICAL RESEARCH FOR NURSING   18 ( 2 )   199 - 206   2016.3

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    DOI： 10.1177/1099800415594452

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  • Can Wound Exudate from Venous Leg Ulcers Measure Wound Pain Status?: A Pilot Study. Reviewed International journal

    Taichi Goto, Nao Tamai, Gojiro Nakagami, Aya Kitamura, Ayumi Naito, Masayuki Hirokawa, Chisako Shimokawa, Kazuo Takahashi, Junichi Umemoto, Hiromi Sanada

    PloS one   11 ( 12 )   e0167478   2016

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    DOI： 10.1371/journal.pone.0167478

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  • The difference of long-term hair recovery among chemotherapeutic regimens in breast cancer patients.

    Hiroshi Yagata, Takanori Watanabe, Hiroko Okada, Mitsue Saito, Tomoko Takayama, Hirohisa Imai, Yuko Yoshida, Nao Tamai, Keiko Nozawa, Tamiko Yajima, Takafumi Sangai, Akiyo Yoshimura, Yoshie Hasegawa, Takako Doi, Yasuo Ohashi, Kojiro Shimozuma

    JOURNAL OF CLINICAL ONCOLOGY   33 ( 15 )   2015.5

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  • National survey of long-term recovery from chemotherapy-induced hair loss in patients with breast cancer

    Hiroshi Yagata, Takanori Watanabe, Hiroko Okada, Mitsue Saito, Tomoko Takayama, Hirohisa Imai, Yuko Yoshida, Nao Tamai, Keiko Nozawa, Tamiko Yajima, Kojiro Shimozuma

    CANCER RESEARCH   75   2015.5

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  • National survey of chemotherapy-induced appearance issues in breast cancer patients

    Takanori Watanabe, Hiroshi Yagata, Mitsue Saito, Hiroko Okada, Tomoko Takayama, Hirohisa Imai, Yuko Yoshida, Nao Tamai, Keiko Nozawa, Tamiko Yajima, Kojiro Shimozuma

    CANCER RESEARCH   75   2015.5

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  • 英語で発表してみよう 静脈性足潰瘍からの滲出液中の疼痛マーカーとしての神経成長因子は遠赤外線温度計により測定した体温上昇により評価した炎症度と関連する(Nerve growth factor as a pain biomarker in exudate from venous leg ulcers is associated with inflammation along with temperature increase evaluated by infrared thermographic assessment)

    Goto Taichi, Tamai Nao, Nakagami Gojiro, Kitamura Aya, Naito Ayumi, Hirokawa Masayuki, Shimokawa Chisako, Sanada Hiromi

    日本創傷・オストミー・失禁管理学会誌   19 ( 2 )   199 - 199   2015.4

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  • The production process for continuous use therapeutic footwear for people with diabetes Reviewed

    Yamada Amika, Kadowaki Takashi, Mori Taketoshi, Sanada Hiromi, Oe Makoto, Ohashi Yumiko, Amemiya Ayumi, Takano Manabu, Noguchi Hiroshi, Tamai Nao, Nishizawa Tomoe, Ueki Kohjiro

    Journal of Nursing Science and Engineering   2 ( 1 )   15 - 24   2015.1

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  • Typical Bioengineering Nursing Research

    Makoto Oe, Nao Tamai, Mikako Yoshida, Koichi Yabunaka

    Bioengineering Nursing: New Horizons of Nursing Research   167 - 202   2014.4

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  • Nursing Biology

    Takeo Minematsu, Nao Tamai, Yoshimi Nishijima

    Bioengineering Nursing: New Horizons of Nursing Research   25 - 60   2014.4

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  • 高齢者施設における皮膚疾患の大規模疫学調査、皮膚真菌症遠隔診断技術の開発、ならびに治療指針の策定 Reviewed

    常深 祐一郎, 玉井 奈緒, 仲上 豪二朗, 真田 弘美, 三浦 由佳, 小谷野 結衣子, 金澤 寿樹, 雨宮 歩, 麦田 裕子, 木村 奈緒, 吉田 美香子, 竹原 君江, 岸 千尋, 川島 眞

    大和証券ヘルス財団研究業績集   ( 37 )   41 - 47   2014.3

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  • Objective evaluation for venous leg ulcer-related nociceptive pain using thermography

    Taichi Goto, Ayumi Naito, Nao Tamai, Gojiro Nakagami, Makoto Mo, Hiromi Sanada

    CHRONIC WOUND CARE MANAGEMENT AND RESEARCH   1   23 - 30   2014

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    DOI： 10.2147/CWCMR.S67054

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  • Health-related quality of life and associated factors in patients with primary lymphedema. Reviewed

    Shizuko Okajima, Akio Hirota, Emiko Kimura, Misako Inagaki, Nao Tamai, Shinji Iizaka, Gojiro Nakagami, Taketoshi Mori, Junko Sugama, Hiromi Sanada

    Japan journal of nursing science : JJNS   10 ( 2 )   202 - 11   2013.12

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    DOI： 10.1111/j.1742-7924.2012.00220.x

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  • Risk factors and risk scoring tool for infection during tissue expansion in tissue expander and implant breast reconstruction Reviewed

    Hirofumi Kato, Gojiro Nakagami, Yoshiko Iwahira, Reiko Otani, Takashi Nagase, Shinji Iizaka, Nao Tamai, Yutaka Matsuyama, Hiromi Sanada

    Breast Journal   19 ( 6 )   618 - 626   2013.11

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    DOI： 10.1111/tbj.12175

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  • Morphological characteristics of and factors related to moisture-associated dermatitis surrounding malignant wounds in breast cancer patients Reviewed International journal

    Nao Tamai, Motoko Horii, Kimie Takehara, Shizuko Kato, Yuko Yamamoto, Ayumi Naito, Mikiko Tayama, Yoko Tamahashi, Seigo Nakamura, Takafumi Kadono, Makoto Oe, Takashi Nagase, Hiromi Sanada

    EUROPEAN JOURNAL OF ONCOLOGY NURSING   17 ( 5 )   673 - 680   2013.10

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    DOI： 10.1016/j.ejon.2013.05.005

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  • パウチを用いた新しい男性用尿失禁ケア用具の開発と評価

    駒形 和典, 仲上 豪二朗, 玉井 奈緒, 加藤 啓史, 杉本 隆, 飯坂 真司, 須釜 淳子, 繁田 佳映, 真田 弘美

    日本創傷・オストミー・失禁管理学会誌   17 ( 1 )   11 - 22   2013.4

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  • 乳癌癌性創傷を有する患者の創部痛の実態と関連する要因

    玉井 奈緒, 堀井 素子, 加藤 静子, 竹原 君江, 内藤 亜由美, 大江 真琴, 赤瀬 智子, 長瀬 敬, 真田 弘美

    日本創傷・オストミー・失禁管理学会誌   17 ( 2 )   119 - 119   2013.4

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  • 【ガイドラインに基づく乳がんケアQ&A チーム医療のために】再発治療 皮膚転移のスキンケアは、どのように行えばよいでしょうか?

    玉井 奈緒

    ナーシングケアQ&A   ( 28 )   139 - 140   2009.1

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MISC

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Awards

  • 学術論文奨励賞

    2018.5   日本創傷・オストミー・失禁管理学会   Situation of occurrence and morphological characteristics of pressure ulcers among inpatients with mental illness

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  • 学術論文奨励賞

    2013.5   第22回日本創傷・オストミー・失禁管理学会学術集会   Evaluation of skin temperature, humidity, and comfort of two types of absorbent products for urinary incontinence

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  • 会長賞

    2013.5   第22回日本創傷・オストミー・失禁管理学会学術集会   乳癌癌性創傷を有する患者の創部痛の実態と関連する要因

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  • 老年消化器病研究会賞

    2004.6   老年消化器病研究会   胃切除患者の加齢に伴う栄養状態の実態

    玉井 奈緒, 永川 宅和, 真田 弘美, 紺家 千津子, 越野守絵, 米村豊, 松木伸夫

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Research Projects

  • ケア資源追跡リアルワールドデータによるケアプロセスの評価方法の開発

    Grant number：25K02910  2025.4 - 2029.3

    日本学術振興会  科学研究費助成事業  基盤研究(B)

    高橋 聡明, 美代 賢吾, 真田 弘美, 仲上 豪二朗, 玉井 奈緒

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    Grant amount：\18720000 （ Direct Cost: \14400000 、 Indirect Cost：\4320000 ）

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  • カテーテル術後患者の退院後の生活を支援するAI活用型オンラインシステムの開発

    Grant number：24K13734  2024.4 - 2028.3

    日本学術振興会  科学研究費助成事業  基盤研究(C)

    土肥 眞奈, 玉井 奈緒, 田中 明日美, 劉 彦, 西山 由紀子, 叶谷 由佳

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    Grant amount：\4550000 （ Direct Cost: \3500000 、 Indirect Cost：\1050000 ）

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  • Development of a futuristic self-care system combining a robotic chair and a healthcare avatar

    Grant number：24H00660  2024.4 - 2028.3

    Japan Society for the Promotion of Science  Grants-in-Aid for Scientific Research  Grant-in-Aid for Scientific Research (A)

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    Grant amount：\47840000 （ Direct Cost: \36800000 、 Indirect Cost：\11040000 ）

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  • Development of pelvic floor muscle training support system using self-ultrasonography and AI care recommendation

    Grant number：22K19685  2022.6 - 2025.3

    Japan Society for the Promotion of Science  Grants-in-Aid for Scientific Research  Grant-in-Aid for Challenging Research (Exploratory)

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    Grant amount：\6240000 （ Direct Cost: \4800000 、 Indirect Cost：\1440000 ）

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  • スマートセンサーとAIによるがん性皮膚潰瘍においモニタリング・ケアシステムの開発

    Grant number：23K24642  2022.4 - 2026.3

    日本学術振興会  科学研究費助成事業  基盤研究(B)

    玉井 奈緒, 峰松 健夫, 真田 弘美, 高橋 聡明

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    Grant amount：\17290000 （ Direct Cost: \13300000 、 Indirect Cost：\3990000 ）

    今年度の研究目的：がん性皮膚潰瘍におけるスマートにおいセンサーの使用可能性の検討
    取り組んだ成果：①がん性皮膚潰瘍のにおいを検知可能かつ、在宅等で患者が拘束されることなく簡便に使用可能なスマートにおいセンサーの探索を行った。福祉機器展への参加や各種学会に参加し、臭気に関連する企業等と検討を重ねた。その中で、いくつかにおい検知センサーの候補が挙がり、該当企業からの説明・交渉の結果、noseStick(I-PEX）を採用した。noseStickはまだ開発されたばかりであるが、患者の簡便性を考慮して選択した。②noseStickのにおい検知の使用可能性を検証するため、がん性皮膚潰瘍の原因物質について各検索エンジンにて、文献検索を実施した。③文献検索の結果（ポリアミンや有機酸等）をもとに、noseStickのにおい識別検知素子を選択した。（企業の制作の都合上、におい識別検知素子の入手に時間を要した）④におい識別検知素子で、実際のがん性皮膚潰瘍のにおいを模倣した臭気の検知が可能であるか、また検知の精度について、現在も実験を継続している。⑤また並行して、臨床調査に向けて倫理申請をおこなうとともに、臨床現場の調整中を実施している。
    今後は、スマートにおいセンサーの使用可能性の成果をまとめるとともに、noseStickと従来のにおいセンサーで検知した成分の一致度と臭気の強さの相関についても分析を実施する準備をおこなっている。

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  • Evaluation of the Prevention of Pneumonia by an Intervention Based on a Database of Swallowing Visualization Using Ultrasonography in the Home Care Settings

    Grant number：23K24630  2022.4 - 2026.3

    Japan Society for the Promotion of Science  Grants-in-Aid for Scientific Research  Grant-in-Aid for Scientific Research (B)

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    Grant amount：\16900000 （ Direct Cost: \13000000 、 Indirect Cost：\3900000 ）

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  • Effectiveness of an Intervention for Preventing Pneumonia Based on a Database of Swallowing Ultrasound in Home Care Settings

    Grant number：22H03372  2022.4 - 2026.3

    Japan Society for the Promotion of Science  Grants-in-Aid for Scientific Research  Grant-in-Aid for Scientific Research (B)

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    Grant amount：\16900000 （ Direct Cost: \13000000 、 Indirect Cost：\3900000 ）

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  • スマートセンサーとAIによるがん性皮膚潰瘍においモニタリング・ケアシステムの開発

    Grant number：22H03384  2022.4 - 2026.3

    日本学術振興会  科学研究費助成事業  基盤研究(B)

    玉井 奈緒, 峰松 健夫, 真田 弘美, 高橋 聡明

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    Grant amount：\17290000 （ Direct Cost: \13300000 、 Indirect Cost：\3990000 ）

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  • Development and implementation of a remote learning system for medical ultrasound technology for home care nurses

    Grant number：23K21562  2021.4 - 2025.3

    Japan Society for the Promotion of Science  Grants-in-Aid for Scientific Research  Grant-in-Aid for Scientific Research (B)

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    Grant amount：\17680000 （ Direct Cost: \13600000 、 Indirect Cost：\4080000 ）

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  • Development and implementation of a remote learning system for medical ultrasound technology for home care nurses

    Grant number：21H03262  2021.4 - 2025.3

    Japan Society for the Promotion of Science  Grants-in-Aid for Scientific Research  Grant-in-Aid for Scientific Research (B)

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    Grant amount：\17680000 （ Direct Cost: \13600000 、 Indirect Cost：\4080000 ）

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  • Development of an noninvasive liquid assessment technologies for smart home-care

    Grant number：20H00560  2020.4 - 2024.3

    Japan Society for the Promotion of Science  Grants-in-Aid for Scientific Research Grant-in-Aid for Scientific Research (A)  Grant-in-Aid for Scientific Research (A)

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    Grant amount：\44850000 （ Direct Cost: \34500000 、 Indirect Cost：\10350000 ）

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  • Development of skin dressing for pressure ulcder prevention to show the tissue damage

    Grant number：19K22744  2019.6 - 2022.3

    Japan Society for the Promotion of Science  Grants-in-Aid for Scientific Research Grant-in-Aid for Challenging Research (Exploratory)  Grant-in-Aid for Challenging Research (Exploratory)

    Minematsu Takeo

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    Grant amount：\6240000 （ Direct Cost: \4800000 、 Indirect Cost：\1440000 ）

    This study aimed to establish the skin blot examination for ATP as a method to identify a precursor condition of pressure injury.
    First, we investigated the applicability of ATP for blotting using nitrocellulose and nylon membrane. Nylon membrane showed low background, high adsorbability, and quantitativity in ATP blotting. Then, we performed skin blotting by nylon membrane on the compressed skin of the hyperemia, erythema, and purpura model mice, and measured ATP on the samples. Tissue damage was detected in all models, and detection intensity reflected the severity of skin damage.These results suggested the applicability of ATP examination by skin blotting with nylon membrane for prediction of pressure injuries.

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  • 抗がん剤脱毛時の頭皮悪化が予測できるウィッグ装着型ウェアラブル端末の開発

    Grant number：19H03931  2019.4 - 2023.3

    日本学術振興会  科学研究費助成事業 基盤研究(B)  基盤研究(B)

    内山 美枝子, 横野 知江, 柏 美智, 坂上 百重, 玉井 奈緒, 峰松 健夫, 黒瀬 雅之, 坂井 さゆり, 李 鎔範, 飯島 淳彦, 奥田 明子, 小山 諭

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    Grant amount：\17030000 （ Direct Cost: \13100000 、 Indirect Cost：\3930000 ）

    本研究は、抗がん剤投与における頭皮の炎症レベルとの関連を見つけるために、①抗がん剤投与による頭皮炎症レベルの決定と②炎症レベルを教師データとし、入力データに頭皮状態の測定結果を採用した機械学習（人工知能の１つ）を、新潟大学ビックデータアクティベーションにて行うことで医学的なエビデンスをつけた抗がん剤投与中の頭皮の炎症レベルと頭皮状態の変化シグナルと関連を提示することを目的とし、時系列的に悪化が予測できるウィッグ装着型のウェアラブル端末の開発を最終目標としている。今年度は①温湿度に着目し、外部環境にかかわる頭部状態の検証及び②頭皮の画像解析の方策の検討を行った。①方法は、毛髪を有した健常女性35名、脱毛がありウィッグを装着している女性4名、計39名を対象に，人工気候室にて、2条件の設定下（①：温度28℃・湿度50％、②：温度30℃・湿度50％）で15分の軽作業による滞在中の頭部内の温湿度測定を行った。測定部位は頭頂部（以下A）、右側頭部（以下B）、左側頭部（以下C）、後頭部（以下D）の4か所とした。結果、測定部位による温湿度について全対象の測定結果から、①条件では温度は（34・55℃）が高値で湿度はＤ（50.97％）が高値であった。②条件ではC（35.30℃）がすべての部位より高値であり、湿度はD（50.85％）と最も高値を示した。②乳がんによる抗がん剤治療を受けた患者4名、健常者34名についてUSBマイクロスコープを用いて頭部画像を撮影し、グレーレベル同時生起行列（GLCM）を用いた特徴量解析をした結果、GLCM特徴量のうち、均質性、明度・彩度、相関、逆差分では脱毛頭皮と健常者の頭皮の間に有意差がみられた。脱毛頭皮と健常者の頭皮の状態は異なると考えられ、脱毛時の頭皮構造と不快症状との関連について検証を進める一助となることが示唆された。

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  • Risk factors of scalp itching for establishing scalp care in patients with hair loss undergoing chemotherapy

    Grant number：19K10947  2019.4 - 2022.3

    Japan Society for the Promotion of Science  Grants-in-Aid for Scientific Research  Grant-in-Aid for Scientific Research (C)

    Tamai Nao

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    Grant amount：\4290000 （ Direct Cost: \3300000 、 Indirect Cost：\990000 ）

    This study aim was to explore risk factors of scalp itching and to evaluate appropriate scalp care in patients with hair loss undergoing chemotherapy. Secondary data analysis, basic experiments, and a case study was conducted. As the results, the skin becomes thinner and is prone to decreased transdermal epidermal water loss by chemotherapy administration. The skin became fragility by chemotherapy. Therefore, we provided another wig made of skin-friendly material including silk protein for the patients who used a medical wig and developed scalp itching and scalp disorders. In the patient, the itching was reduced the next day and followed by improvement of skin disorders. In other words, it is highly likely that itching can be suppressed by reducing external stimuli.

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  • Development of the examination of genetic polymorphisms to identify high risk patients for pressure ulcer occurence

    Grant number：18H03068  2018.4 - 2021.3

    Japan Society for the Promotion of Science  Grants-in-Aid for Scientific Research Grant-in-Aid for Scientific Research (B)  Grant-in-Aid for Scientific Research (B)

    Minematsu Takeo

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    Grant amount：\17290000 （ Direct Cost: \13300000 、 Indirect Cost：\3990000 ）

    This study aimed to identify the genetic factors to the pressure injury. An animal experiment and a clinical study which targeted on 6 genes (HIF1A、VEGFC、 MSTN、PAI1、HSP90AA1, VDR) were conducted.
    In the animal experiment, we introduced expression vector or siRNA of six genes followed by pressure loading in the skin. The results indicated that the over-expression or inhibition of these genes resulted in the severer tissue damage of the compressed skin.
    In the clinical study, we analyzed the association between eight SNPs of six genes and pressure injuries in the hospitalized older patients. The multiple regression analysis indicated the significant association of VEGFC (rs1485766) and HIF1A (rs11549465) with shallow and deep pressure injuries, respectively.

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  • Concept of scalp care in patients with chemotherapy-induced alopecia

    Grant number：16K20749  2016.4 - 2019.3

    Japan Society for the Promotion of Science  Grants-in-Aid for Scientific Research Grant-in-Aid for Young Scientists (B)  Grant-in-Aid for Young Scientists (B)

    Tamai Nao

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    Grant amount：\3770000 （ Direct Cost: \2900000 、 Indirect Cost：\870000 ）

    This study was aimed to determine scalp symptoms, alteration of scalp barrier function, and concept of scalp care in patients with breast cancer receiving chemotherapy.Fifty patients were recruited. We evaluated scalp barrier function by assessing trans-epidermal water loss (TEWL) and skin pH on scalp region.
    Results:1) Patients had the following symptoms-pain, itching, erythema, rash, and erosion. Median values of TEWL decreased than standard value. 2) The incidence of pain and itching increased in the 3rd week. The incidence of erythema and rash in the 13th week increased than that in the 3rd week. TEWL and skin-pH decreased in the last chemotherapy administration. 3) The incidence of dermatitis, including erythema, rash, and erosion, decreased when wearing the new hypoallergenic medical wig.

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  • Development of comprehensive evaluation of local and systemic condition by skin blotting

    Grant number：15H05066  2015.4 - 2018.3

    Japan Society for the Promotion of Science  Grants-in-Aid for Scientific Research Grant-in-Aid for Scientific Research (B)  Grant-in-Aid for Scientific Research (B)

    Minematsu Takeo

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    Grant amount：\15470000 （ Direct Cost: \11900000 、 Indirect Cost：\3570000 ）

    To establish the comprehensive assessment of skin local condition and systemic condition by skin blotting method which noninvasively extracts soluble proteins from skin tissue, we conducted the animal experiments and clinical studies. These results indicated that albumin extraction depends on the skin barrier function, and internal standard markers to normalize the extraction efficiency in skin blotting. Albumin and Annexin A2 are the promising internal standard markers. Furthermore, it is reported that skin blotting detecting NGFb and taurine reflects to itching and dehydration in older people.

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  • Principle and application of skin blotting method

    Grant number：26670914  2014.4 - 2016.3

    Japan Society for the Promotion of Science  Grants-in-Aid for Scientific Research Grant-in-Aid for Challenging Exploratory Research  Grant-in-Aid for Challenging Exploratory Research

    MINEMATSU Takeo, SANADA Hiromi, MORI Taketoshi, NAKAGAMI Gojiro, NOGUCHI Hiroshi, TAMAI Nao

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    Grant amount：\3640000 （ Direct Cost: \2800000 、 Indirect Cost：\840000 ）

    (1)The principle of skin blotting: We could not fully reveal the principle of skin blotting within this period. Conventional techniques are not enough for the analysis of the effect of skin blotting on the inter-corneocyte lipid lamellae structure. Therefore, we developed new fixation technique of skin tissue, which can keep the structures of inter-corneocyte lipid, epidermis and dermis. Furthermore, the temporal structural change by skin blotting was suggested by immunofluorescence for claudin-1, a tight junction protein.
    (2)In the animal experiment, we identified the biomarkers for early detection of pressure ulcer development by skin blotting. The biomarkers are PAI1, VEGF-C, IL1a, and HSP90a, which reflected the ischemia, lymphatic dysfunction, ischemia-reperfusion injury, and deformation of tissue, respectively.

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  • Round Re-Engineering Based on Action Log Analysis of Both Patients and Nurses

    Grant number：25282174  2013.4 - 2017.3

    Japan Society for the Promotion of Science  Grants-in-Aid for Scientific Research Grant-in-Aid for Scientific Research (B)  Grant-in-Aid for Scientific Research (B)

    MORI Taketoshi

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    Grant amount：\17940000 （ Direct Cost: \13800000 、 Indirect Cost：\4140000 ）

    We developed an infrastructure installation type measurement system that casually and naturally quantifies the behavior and movement of patients, nurses or mutual interactions. Based on that, we proceeded to develop an enhanced system that supports nurses' room round seeking appropriate timing, time, basic care contents on evidence basis from these 24-hour accumulation data.

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  • Development of objective evaluation for wound pain in eldery patients with chronic wounds

    Grant number：25870179  2013.4 - 2016.3

    Japan Society for the Promotion of Science  Grants-in-Aid for Scientific Research Grant-in-Aid for Young Scientists (B)  Grant-in-Aid for Young Scientists (B)

    TAMAI Nao

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    Grant amount：\4420000 （ Direct Cost: \3400000 、 Indirect Cost：\1020000 ）

    To clarify the associations between the self-evaluated pain status and, skin temprature and two pain biomarker candidate in exudate from venous leg ulcer (VLU) for establishment of an objective pain evaluation. Each participant with VLU self-evaluated their pain status at each examination using the numerical rating scale and the short-form McGill Pain Questionnaire 2. The NGF and S100A8/A9 concentrations in the VLU exudate were measured by enzyme-linked immunosorbent assay. The association between each pain status and, skin temprature and the two standardized protein concentrations was evaluated. Thirteen participants were analyzed. The pain intensity of the high temperature group was significantly higher than the normal temperature group. The standardized NGF concentration was negatively correlated with continuous, intermittent, and neuropathic pain. The standardized S100A8/A9 concentration was positively correlated with present pain intensity.

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  • Online posture estimation using pressure distribution on air mattress for pressure ulcer prevention

    Grant number：25560280  2013.4 - 2015.3

    Japan Society for the Promotion of Science  Grants-in-Aid for Scientific Research Grant-in-Aid for Challenging Exploratory Research  Grant-in-Aid for Challenging Exploratory Research

    NOGUCHI Hiroshi, TAMAI Nao, YOSHIDA Mikako, SANADA Hiromi

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    Grant amount：\3510000 （ Direct Cost: \2700000 、 Indirect Cost：\810000 ）

    We constructed methods for estimation of body sinking distance and postures on an air mattress using pressure distribution sensors. The body sinking distance is estimated based on investigated non-linear relationship between pressure values and sinking distances. The posture is estimated by using machine learning technique. The distance estimation method was evaluated based on the dataset that includes body sinking distance during head of bed elevation. We also prepared dataset about posture dataset on supine, right and left lateral position, 30-degree and maximum inclination of bed. The experiment demonstrated that our method had good performance.

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  • Development of "Bioengineering Nursing" in Nursing Science

    Grant number：23249088  2011.4 - 2015.3

    Japan Society for the Promotion of Science  Grants-in-Aid for Scientific Research Grant-in-Aid for Scientific Research (A)  Grant-in-Aid for Scientific Research (A)

    SANADA Hiromi, SUGAMA Junko, NAGASE Takashi, NAKAGAMI Gojiro, MINEMATSU Takeo, MORI Taketoshi, OE Makoto, MURAYAMA Ryoko, YOSHIDA Mikako, IIZAKA Shinji, NOGUCHI Hiroshi, TAMAI Nao

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    Grant amount：\47060000 （ Direct Cost: \36200000 、 Indirect Cost：\10860000 ）

    Bioengineering Nursing is a nursing science collaborating with molecular biology and engineering. In order to establish this new science, (1) conducting the model study, and (2) education of bioengineering nursing were conducted in this study.
    (1) Model study: We conducted molecular biological and/or engineering studies on the development of assessment tools, the preventive techniques and devices for cutaneous wounds, and the devices and drugs to promote healing of chronic wounds.
    (2) Educations: We firstly published the textbook “Bioengineering Nursing: New Horizons of Nursing Research”. Then the basic seminars of bioengineering nursing were held twice in 2013 and 2014. Some of graduates made and conducted the own study plan on bioengineering nursing while receiving our supports.

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