-
Single-Cell RNA-Seq Reveals <i>LRRC75A</i>-Expressing Cell Population Involved in VEGF Secretion of Multipotent Mesenchymal Stromal/Stem Cells Under Ischemia
Takumi Miura, Tsukasa Kouno, Megumi Takano, Takuya Kuroda, Yumiko Yamamoto, Shinji Kusakawa, Masaki Suimye Morioka, Tohru Sugawara, Takamasa Hirai, Satoshi Yasuda, Rumi Sawada, Satoko Matsuyama, Hideya Kawaji, Takeya Kasukawa, Masayoshi Itoh, Akifumi Matsuyama, Jay W Shin, Akihiro Umezawa, Jun Kawai, Yoji Sato
Stem Cells Translational Medicine
12
(
6
)
379
-
390
2023.6
-
A single allele of the hsa-miR-302/367 cluster maintains human pluripotent stem cells
Reviewed
Tohru Sugawara, Yuki Kawamoto, Tomoyuki Kawasaki, Akihiro Umezawa, Hidenori Akutsu
Regenerative Therapy
21
37
-
45
2022.5
-
Using piggyBac transposon gene expression vectors to transfect Zscan5b gene into mouse pluripotent stem cells
Invited
Reviewed
Mitsutoshi Yamada, Tohru Sugawara, Shinju Usami, Rina Nakanishi, Hidenori Akustu
STAR Protoc .
2
(
3
)
100811
2021.9
-
The hsa-miR-302 cluster controls ectodermal differentiation of human pluripotent stem cell via repression of DAZAP2.
International journal
Tohru Sugawara, Takumi Miura, Tomoyuki Kawasaki, Akihiro Umezawa, Hidenori Akutsu
Regenerative therapy
15
1
-
9
2020.12
-
Identification and therapeutic rescue of autophagosome and glutamate receptor defects in C9ORF72 and sporadic ALS neurons.
Reviewed
Shi Y, Hung ST, Rocha G, Lin S, Linares GR, Staats KA, Seah C, Wang Y, Chickering M, Lai J, Sugawara T, Sagare AP, Zlokovic BV, Ichida JK
JCI insight
5
2019.7
-
Zscan5b Deficiency Impairs DNA Damage Response and Causes Chromosomal Aberrations during Mitosis.
Reviewed
International journal
Ogawa S, Yamada M, Nakamura A, Sugawara T, Nakamura A, Miyajima S, Harada Y, Ooka R, Okawa R, Miyauchi J, Tsumura H, Yoshimura Y, Miyado K, Akutsu H, Tanaka M, Umezawa A, Hamatani T
Stem cell reports
12
(
6
)
1366
-
1379
2019.6
-
Epigenetic-scale comparison of human iPSCs generated by retrovirus, Sendai virus or episomal vectors.
Reviewed
International journal
Koichiro Nishino, Yoshikazu Arai, Ken Takasawa, Masashi Toyoda, Mayu Yamazaki-Inoue, Tohru Sugawara, Hidenori Akutsu, Ken Nishimura, Manami Ohtaka, Mahito Nakanishi, Akihiro Umezawa
Regenerative therapy
9
71
-
78
2018.12
-
Haploinsufficiency leads to neurodegeneration in C9ORF72 ALS/FTD human induced motor neurons.
Reviewed
Shi Y, Lin S, Staats KA, Li Y, Chang WH, Hung ST, Hendricks E, Linares GR, Wang Y, Son EY, Wen X, Kisler K, Wilkinson B, Menendez L, Sugawara T, Woolwine P, Huang M, Cowan MJ, Ge B, Koutsodendris N, Sandor KP, Komberg J, Vangoor VR, Senthilkumar K, Hennes V, Seah C, Nelson AR, Cheng TY, Lee SJ, August PR, Chen JA, Wisniewski N, Hanson-Smith V, Belgard TG, Zhang A, Coba M, Grunseich C, Ward ME, van den Berg LH, Pasterkamp RJ, Trotti D, Zlokovic BV, Ichida JK
Nature medicine
24
(
3
)
313
-
325
2018.3
-
Organoids recapitulate organs?
Reviewed
International journal
Tohru Sugawara, Kengo Sasaki, Hidenori Akutsu
Stem cell investigation
5
3
-
3
2018
-
Generation of primitive neural stem cells from human fibroblasts using a defined set of factors
Reviewed
Takumi Miura, Tohru Sugawara, Atsushi Fukuda, Ryo Tamoto, Tomoyuki Kawasaki, Akihiro Umezawa, Hidenori Akutsu
BIOLOGY OPEN
4
(
11
)
1595
-
1607
2015.11
-
Central role for PICALM in amyloid-beta blood-brain barrier transcytosis and clearance
Reviewed
Zhen Zhao, Abhay P. Sagare, Qingyi Ma, Matthew R. Halliday, Pan Kong, Kassandra Kisler, Ethan A. Winkler, Anita Ramanathan, Takahisa Kanekiyo, Guojun Bu, Nelly Chuqui Owens, Sanket V. Rege, Gabriel Si, Ashim Ahuja, Donghui Zhu, Carol A. Miller, Julie A. Schneider, Manami Maeda, Takahiro Maeda, Tohru Sugawara, Justin K. Ichida, Berislav V. Zlokovic
NATURE NEUROSCIENCE
18
(
7
)
978
-
+
2015.7
-
Xenogeneic-free defined conditions for derivation and expansion of human embryonic stem cells with mesenchymal stem cells
Reviewed
Hidenori Akutsu, Masakazu Machida, Seiichi Kanzaki, Tohru Sugawara, Takashi Ohkura, Naoko Nakamura, Mayu Yamazaki-Inoue, Takumi Miura, Mohan C. Vemuri, Mahendra S. Rao, Kenji Miyado, Akihiro Umezawa
Regenerative Therapy
1
18
-
29
2015.6
-
beta-Catenin Functions Pleiotropically in Differentiation and Tumorigenesis in Mouse Embryo-Derived Stem Cells
Reviewed
Noriko Okumura, Hidenori Akutsu, Tohru Sugawara, Takumi Miura, Youki Takezawa, Akihiro Hosoda, Keiichi Yoshida, Justin K. Ichida, Mitsutoshi Yamada, Toshio Hamatani, Naoaki Kuji, Kenji Miyado, Yasunori Yoshimura, Akihiro Umezawa
PLOS ONE
8
(
5
)
e63265
2013.5
-
Correlation between Nuptial Colors and Visual Sensitivities Tuned by Opsins Leads to Species Richness in Sympatric Lake Victoria Cichlid Fishes
Reviewed
Ryutaro Miyagi, Yohey Terai, Mitsuto Aibara, Tohru Sugawara, Hiroo Imai, Hidenori Tachida, Semvua Isa Mzighani, Takashi Okitsu, Akimori Wada, Norihiro Okada
MOLECULAR BIOLOGY AND EVOLUTION
29
(
11
)
3281
-
3296
2012.11
-
Eco-Geographical Diversification of Bitter Taste Receptor Genes (TAS2Rs) among Subspecies of Chimpanzees (Pan troglodytes)
Reviewed
Takashi Hayakawa, Tohru Sugawara, Yasuhiro Go, Toshifumi Udono, Hirohisa Hirai, Hiroo Imai
PLOS ONE
7
(
8
)
e43277
2012.8
-
Investigating cellular identity and manipulating cell fate using induced pluripotent stem cells
Reviewed
Tohru Sugawara, Koichiro Nishino, Akihiro Umezawa, Hidenori Akutsu
STEM CELL RESEARCH & THERAPY
3
(
2
)
8
2012.3
-
Reverse Evolution in RH1 for Adaptation of Cichlids to Water Depth in Lake Tanganyika
Reviewed
Haruka Nagai, Yohey Terai, Tohru Sugawara, Hiroo Imai, Hidenori Nishihara, Michio Hori, Norihiro Okada
MOLECULAR BIOLOGY AND EVOLUTION
28
(
6
)
1769
-
1776
2011.6
-
Diversification of Bitter Taste Receptor Gene Family in Western Chimpanzees
Reviewed
Tohru Sugawara, Yasuhiro Go, Toshifumi Udono, Naruki Morimura, Masaki Tomonaga, Hirohisa Hirai, Hiroo Imai
MOLECULAR BIOLOGY AND EVOLUTION
28
(
2
)
921
-
931
2011.2
-
Identification of non-taster Japanese macaques for a specific bitter taste
Reviewed
Nami Suzuki, Tohru Sugawara, Atsushi Matsui, Yasuhiro Go, Hirohisa Hirai, Hiroo Imai
PRIMATES
51
(
4
)
285
-
289
2010.10
-
Vertebrate Rhodopsin Adaptation to Dim Light via Rapid Meta-II Intermediate Formation
Reviewed
Tohru Sugawara, Hiroo Imai, Masato Nikaido, Yasushi Imamoto, Norihiro Okada
MOLECULAR BIOLOGY AND EVOLUTION
27
(
3
)
506
-
519
2010.3
-
Polymorphisms in the GPCRs of primates and the genetic database on the individual primates in the Primate Research Institute
Reviewed
Imai Hiroo, Sugawara Tohru, Go Yasuhiro, Matsui Atsushi, Nishimura Osamu, Inoue Eiji, Murayama Miho, Hirai Hirohisa, Agata Kiyokazu, Matsuzawa Tetsuro
NEUROSCIENCE RESEARCH
65
S176
2009
-
Divergent selection on opsins drives incipient speciation in Lake Victoria cichlids
Reviewed
Yohey Terai, Ole Seehausen, Takeshi Sasaki, Kazuhiko Takahashi, Shinji Mizoiri, Tohru Sugawara, Tetsu Sato, Masakatsu Watanabe, Nellie Konijnendijk, Hillary D. J. Mrosso, Hidenori Tachida, Hiroo Imai, Yoshinori Shichida, Norihiro Okada
PLoS Biology
4
(
12
)
2244
-
2251
2006.12
-
Parallelism of amino acid changes at the RH1 affecting spectral sensitivity among deep-water cichlids from Lakes Tanganyika and Malawi
Reviewed
T Sugawara, Y Terai, H Imai, GF Turner, S Koblmuller, C Sturmbauer, Y Shichida, N Okada
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
102
(
15
)
5448
-
5453
2005.4
-
Natural selection of the rhodopsin gene during the adaptive radiation of East African Great Lakes Cichlid fishes
Reviewed
T Sugawara, Y Terai, N Okada
MOLECULAR BIOLOGY AND EVOLUTION
19
(
10
)
1807
-
1811
2002.10
