Updated on 2025/07/18

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写真a

 
Kazuma Miyatake
 
Organization
Graduate School of Medicine Department of Medicine Orthopedic Surgery Assistant Professor
School of Medicine Medical Course
Title
Assistant Professor
Profile

肩肘関節のスポーツ障害を中心に、エコーやMRI、その他のモダリティーを用いた診断、関節鏡を中心とした手術治療について研究しています。

また、難治性疼痛に対する末梢神経を標的にしたハイドロリリース、高周波パルスに対する臨床成績、基礎実験を行っています。

加えて、超音波ガイド下手術、X線動態解析、VR・MR・XRに対する整形外科的な応用も着手しています。

External link

Degree

  • 博士（医学） ( 2021.3 )

Research Interests

  • 関節鏡

  • 運動器超音波

  • 肘関節

  • 肩関節

  • 末梢神経

  • スポーツ

Research Areas

  • Life Science / Sports sciences

  • Life Science / Anatomy

  • Life Science / Rehabilitation science

  • Life Science / Orthopedics

Papers

  • 肩疾患リハビリテーションにおける超音波の活用 凍結肩のリハビリにエコーを活用する

    河端 将司, 宮田 徹, 直井 大地, 宮武 和馬

    日本肩関節学会学術集会・日本肩の運動機能研究会学術集会抄録集   50回・20回   91 - 91   2023.9

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    Language：Japanese   Publisher：(一社)日本肩関節学会  

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  • 今だから言いたい!私たち裏で治してます!-最新超音波診療に対する理学療法士の本音- サイレント・マニピュレーションに対する本音 大きな声では言えない理学療法

    河端 将司, 宮田 徹, 直井 大地, 宮武 和馬

    日本整形外科超音波学会学術集会プログラム・抄録集   34回   92 - 92   2023.7

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    Language：Japanese   Publisher：日本整形外科超音波学会  

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  • 後果骨折を伴う足関節骨折は足関節背屈可動域と母趾背屈可動域が制限される

    芦原 光明, 河端 将司, 宮田 徹, 直井 大地, 小林 明裕, 宮武 和馬

    日本整形外科超音波学会学術集会プログラム・抄録集   34回   158 - 158   2023.7

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    Language：Japanese   Publisher：日本整形外科超音波学会  

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  • Application of Intraoperative CT-Ultrasound Fusion Imaging in Hip Endoscopy for Treatment of Iatrogenic Impingement Due to PLLA Screw: A Novel Surgical Technique

    Kazuma Miyatake, Hyonmin Choe, Fujisawa Takahiro, Yuusuke Kawabata, Yohei Kusaba, Yutaka Inaba

    Arthroscopy Techniques   12 ( 6 )   e801 - e805   2023.5

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    Publishing type：Research paper (scientific journal)   Publisher：Elsevier BV  

    DOI： 10.1016/j.eats.2023.02.009

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  • Targeting of Periprosthetic Muscles for the Ultrasonographic Screening of Hip Abnormalities in Hip Resurfacing Arthroplasty Patients. International journal

    Hyonmin Choe, Naomi Kobayashi, Koki Abe, Yuta Hieda, Hiroyuki Ike, Ken Kumagai, Kazuma Miyatake, Takahiro Fujisawa, Yutaka Inaba

    Journal of clinical medicine   12 ( 8 )   2023.4

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    Language：English   Publishing type：Research paper (scientific journal)  

    BACKGROUND: Hip resurfacing arthroplasty (HRA) patients require subsequent annual screening for postoperative complications. Ultrasonography may be useful for this purpose but lacks a screening protocol for hips. The purpose of this study was to evaluate the accuracy of ultrasonography for detecting postoperative complications in HRA patients using a screening protocol that specifically targets periprosthetic muscles. METHODS: We enrolled 45 hips from 40 HRA patients with a mean follow-up period of 8.2 years. MRI and ultrasonography scans were simultaneously conducted at follow-up. The ultrasonography assessments were conducted on the anterior part of the hip that targets iliopsoas, sartorius, rectus femoris, lateral with anterior superior and inferior iliac spine (ASIS and AIIS) as bony landmarks, and the lateral and posterior parts that target fascia tensor, short rotators, and gluteus minimus, medius, and maximus with greater trochanter and ischial tuberosity as bony landmarks. The accuracy of diagnosing postoperative abnormalities and the visibility of periprosthetic muscles were compared between these two modalities. RESULTS: Both MRI and ultrasonography detected an abnormal region in eight cases comprising two infections, two pseudotumors, and four patients with greater trochanteric bursitis. Among these cases, four hips required implant removal. The increase in anterior space, measured as the distance between the iliopsoas and resurfacing head, was a good indicator for the abnormal mass in these four HRA cases. In the assessment of periprosthetic muscles, MRI showed a much lower visibility than ultrasonography in the iliopsoas (6.7% vs. 100%), gluteus minimus (6.7% vs. 88.9%), and short rotators (8.8% vs. 71.4%) due to implant halation. CONCLUSIONS: By targeting periprosthetic muscles, ultrasonography can detect postoperative complications as effectively as MRI assessments in HRA patients. Ultrasonography has superior visibility in the periprosthetic muscles of HRA patients, indicating its utility for the screening of small legions in these cases which may not be visible by MRI.

    DOI： 10.3390/jcm12082871

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  • Dynamic sonographic diagnosis of snapping elbow associated with congenital radioulnar synostosis

    Kensuke Kameda, Kazuma Miyatake, Takahiro Fujisawa, Akio Otoshi, Yusuke Kawabata, Yohei Kusaba, Yutaka Inaba

    JSES Reviews, Reports, and Techniques   3 ( 1 )   116 - 119   2023.2

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    Publishing type：Research paper (scientific journal)   Publisher：Elsevier BV  

    DOI： 10.1016/j.xrrt.2022.09.006

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  • 実践講座 リハビリテーション治療に生かすエコー 運動器リハビリテーションにおけるエコーの活用

    宮田 徹, 直井 大地, 芦原 光明, 太附 広明, 河端 将司, 宮武 和馬

    総合リハビリテーション   51 ( 1 )   67 - 72   2023.1

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    Language：Japanese   Publisher：(株)医学書院  

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  • 末梢神経で考える肩関節機能障害に対する評価・治療戦略

    宮武 和馬, 河端 将司, 藤澤 隆弘, 稲葉 裕

    日本肩関節学会学術集会・日本肩の運動機能研究会学術集会抄録集   49回・19回   414 - 414   2022.9

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    Language：Japanese   Publisher：(一社)日本肩関節学会  

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  • Double Level Osteotomy後の膝蓋大腿関節痛に対し内側広筋関節枝への理学療法が奏功した一例

    芦原 光明, 宮田 徹, 河端 将司, 直井 大地, 草場 洋平, 宮武 和馬

    日本整形外科超音波学会学術集会プログラム・抄録集   33回   134 - 134   2022.7

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    Language：Japanese   Publisher：日本整形外科超音波学会  

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  • サイレント・マニピュレーション前後の肩関節下垂位自動外旋に伴う肩前上方結合組織の経時変化

    直井 大地, 河端 将司, 宮田 徹, 芦原 光明, 宮武 和馬

    日本整形外科超音波学会学術集会プログラム・抄録集   33回   112 - 112   2022.7

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  • 理学療法へのエコー活用法～1単位での使い方～ 伏在神経(膝蓋下枝)に対する理学療法

    宮田 徹, 芦原 光明, 河端 将司, 直井 大地, 宮武 和馬

    日本整形外科超音波学会学術集会プログラム・抄録集   33回   73 - 73   2022.7

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    Language：Japanese   Publisher：日本整形外科超音波学会  

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  • サイレント・マニピュレーション後の肩関節外旋後方動態と術後成績の関係

    宮田 徹, 直井 大地, 河端 将司, 芦原 光明, 宮武 和馬

    日本整形外科超音波学会学術集会プログラム・抄録集   33回   113 - 113   2022.7

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    Language：Japanese   Publisher：日本整形外科超音波学会  

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  • Medial meniscus extrusion and stage are related to the size of spontaneous osteonecrosis of the knee in patients who underwent high tibial osteotomy

    Takahiro Fujisawa, Hyonmin Choe, Youhei Kusaba, Yusuke Kawabata, Akio Otoshi, Kazuma Miyatake, Yutaka Inaba

    The Knee   36   72 - 79   2022.6

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    Publishing type：Research paper (scientific journal)   Publisher：Elsevier BV  

    DOI： 10.1016/j.knee.2022.04.011

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  • 知っておきたい・深めたい Close-up 身体内滑走 神経の滑走

    河端 将司, 宮武 和馬, 宮田 徹

    理学療法ジャーナル   56 ( 6 )   702 - 706   2022.6

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    Language：Japanese   Publisher：(株)医学書院  

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  • 軟部腫瘍と鑑別を要した筋損傷の7例における画像的特徴の検討

    斎藤 桂樹, 川端 佑介, 林田 健太, 藤田 真太朗, 荒川 裕和, 宮川 秀俊, 宮武 和馬, 竹山 昌伸, 稲葉 裕

    関東整形災害外科学会雑誌   53 ( 2 )   33 - 33   2022.4

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    Language：Japanese   Publisher：関東整形災害外科学会  

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  • Return to sports activity after opening wedge high tibial osteotomy in patients aged 70 years and older

    Akio Otoshi, Ken Kumagai, Shunsuke Yamada, Shuntaro Nejima, Takahiro Fujisawa, Kazuma Miyatake, Yutaka Inaba

    Journal of Orthopaedic Surgery and Research   16 ( 1 )   2021.12

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    Publishing type：Research paper (scientific journal)   Publisher：Springer Science and Business Media LLC  

    Abstract

    Background

    The purpose of this study was to evaluate return to sports (RTS) after opening wedge high tibial osteotomy (OWHTO) in elderly patients and associated factors affecting RTS.

    Methods

    Seventy-four patients (mean age 68 years) who underwent OWHTO were enrolled. Clinical outcomes were evaluated using the Knee Society Score (KSS). Patients were asked regarding types of sports activities and their levels of participation within preoperative 1 year and postoperative 1 year. Levels of participation in sports and recreational activities were examined using the Tegner activity scale. The outcomes were compared between two age groups (≥ 70 years vs. < 70 years).

    Results

    Of the 74 patients overall, 59 participated in at least one sport preoperatively, and 55 returned to sports postoperatively (RTS 93%). The KSS knee score and function score were significantly improved after surgery in both age groups (P < 0.05), but no significant differences were found between the age groups. The Tegner activity scales for ≥ 70 years and < 70 years were 2.9 ± 1.1 and 4.0 ± 1.9 preoperatively (P < 0.01) and 2.7 ± 1.2 and 3.3 ± 1.4 postoperatively (P = 0.16), respectively. RTS was reported by 24 of 25 (96.0%) in the age < 70 years group and 31 of 34 (91.2%) in the age ≥ 70 years group. Majority of age ≥ 70 years participated in low-impact sports preoperatively and returned to the same impact level postoperatively.

    Conclusions

    The rate of RTS after OWHTO was high in patients aged 70 years and older with low-impact level. OWHTO is a preferred surgical option for elderly patients who desire RTS.

    DOI： 10.1186/s13018-021-02718-6

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    Other Link： https://link.springer.com/article/10.1186/s13018-021-02718-6/fulltext.html

  • Silent Manipulation for Adhesive Capsulitis Reviewed

    Kazuma Miyatake, Takahiro Fujisawa, Akio Otoshi, Yusuke Kawabata, Yohei Kusaba, Shinya Tsujiku, Yutaka Inaba

    Current Physical Medicine and Rehabilitation Reports   2021.11

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    Authorship：Lead author   Publishing type：Research paper (scientific journal)   Publisher：Springer Science and Business Media LLC  

    DOI： 10.1007/s40141-021-00332-5

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    Other Link： https://link.springer.com/article/10.1007/s40141-021-00332-5/fulltext.html

  • 【スポーツ現場における超音波診療】上腕-肘関節周囲のスポーツ外傷・障害に対する超音波を用いたアプローチ

    河端 将司, 宮田 徹, 宮武 和馬

    臨床スポーツ医学   38 ( 11 )   1192 - 1197   2021.11

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    Language：Japanese   Publisher：(株)文光堂  

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  • 【スポーツ現場における超音波診療】大腿-膝関節周囲のスポーツ外傷・障害に対する超音波を用いたアプローチ

    宮田 徹, 河端 将司, 宮武 和馬

    臨床スポーツ医学   38 ( 11 )   1238 - 1242   2021.11

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  • 【スポーツ現場における超音波診療】大腿-膝関節周囲のスポーツ外傷・障害に対する超音波を用いたアプローチ

    宮田 徹, 河端 将司, 宮武 和馬

    臨床スポーツ医学   38 ( 11 )   1238 - 1242   2021.11

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  • 【スポーツ現場における超音波診療】上腕-肘関節周囲のスポーツ外傷・障害に対する超音波を用いたアプローチ

    河端 将司, 宮田 徹, 宮武 和馬

    臨床スポーツ医学   38 ( 11 )   1192 - 1197   2021.11

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  • Ultrasonographic prevalence of ulnar nerve displacement at the elbow in young baseball players International journal

    Masashi Kawabata, Toru Miyata, Hiroaki Tatsuki, Daichi Naoi, Mitsuaki Ashihara, Kazuma Miyatake, Yohei Kusaba, Daiki Watanabe, Masashi Matsuzaki, Yuta Suzuki, Kentaro Kamiya

    PM&R   2021.7

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    Language：English   Publishing type：Research paper (scientific journal)   Publisher：Wiley  

    BACKGROUND: Overhead-throwing athletes are at risk of elbow injury because of valgus stress, leading to unstable ulnar nerves and neuropathy. Studies regarding ulnar nerve damage/displacement have been performed primarily in adults. OBJECTIVE: To determine the prevalence and related factors associated with ulnar nerve displacement at the elbow in young baseball players. DESIGN: Cross-sectional study. PARTICIPANTS: Youth baseball players ages 10-12 years were eligible to participate. Exclusion criteria were history of neuropathic pain, trauma, or prior surgery of the upper limb. Fifty-seven participants were eligible for inclusion in the study. MAIN OUTCOME MEASUREMENTS: Demographic data and ultrasonography findings of ulnar nerve dynamics at the cubital tunnel were analyzed in a total of 114 elbows. Elbows were grouped into nondislocation and displacement (subluxation or dislocation) groups according to ultrasound findings. Logistic generalized estimating equations were used to identify factors associated with ulnar nerve displacement. RESULTS: Thirty-six (31.6%) elbows demonstrated sonographic findings of ulnar nerve displacement, with 13 (11.4%) subluxations and 23 (20.2%) dislocations. Fourteen (24.6%) participants experienced nerve displacement in the dominant elbow only, whereas nerve displacement in both elbows occurred in 11 (19.3%) participants. Nerve displacement in the nondominant elbow only was not observed. Hand dominance and tenderness of the arcade of Struthers' were factors associated with ulnar nerve displacement (odds ratio, 2.81, and 9.73; 95% confidence interval, 1.34-5.91 and 2.45-38.68; p = .006 and .001, respectively). CONCLUSION: One-third of the young baseball players evaluated had ultrasonographic findings compatible with ulnar nerve displacement at the elbow. Hand dominance and tenderness of Struthers arcade were the only factors associated with ulnar nerve displacement. Ultrasound may help identify patients with ulnar nerve displacement and contribute to the understanding of its pathophysiology in young baseball players.

    DOI： 10.1002/pmrj.12658

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    Other Link： https://onlinelibrary.wiley.com/doi/full-xml/10.1002/pmrj.12658

  • サッカー選手における足関節捻挫の既往と距腿関節動態の関連性

    宮田 徹, 芦原 光明, 河端 将司, 直井 大地, 草場 洋平, 宮武 和馬

    日本整形外科超音波学会学術集会プログラム・抄録集   32回   122 - 122   2021.7

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  • 肩関節下垂位外旋における肩前上方結合組織の形態変化に関する視覚的評価

    直井 大地, 河端 将司, 宮田 徹, 芦原 光明, 宮武 和馬, 草場 洋平

    日本整形外科超音波学会学術集会プログラム・抄録集   32回   150 - 150   2021.7

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  • 足関節荷重下背屈運動における距腿関節後方動態の検者内・検者間信頼性の検討

    芦原 光明, 宮田 徹, 河端 将司, 直井 大地, 草場 洋平, 宮武 和馬

    日本整形外科超音波学会学術集会プログラム・抄録集   32回   140 - 140   2021.7

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  • 少年野球選手の尺骨神経脱臼の出現頻度とリスク因子に関する横断的調査

    河端 将司, 宮田 徹, 直井 大地, 芦原 光明, 草場 洋平, 宮武 和馬

    日本整形外科超音波学会学術集会プログラム・抄録集   32回   123 - 123   2021.7

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  • よくある痛みの超音波診療の実際 膝前面痛に対する超音波診療 PTの場合

    河端 将司, 宮田 徹, 宮武 和馬

    超音波医学   48 ( Suppl. )   S462 - S462   2021.4

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  • 運動器エコー普及の背景と将来の展望 SMAP(Sonography for MSK Activating Project)設立の経緯と今後の展望

    笹原 潤, 宮武 和馬

    超音波医学   48 ( Suppl. )   S456 - S456   2021.4

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  • アスリートの難治性疼痛外来からみえたもの 上肢機能障害を末梢神経の「線」で捉えるミカタ

    河端 将司, 宮田 徹, 宮武 和馬

    Journal of Athletic Rehabilitation   17 ( 1 )   30 - 30   2021.2

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    Language：Japanese   Publisher：スポーツ選手のためのリハビリテーション研究会  

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  • Sclerostin inhibits interleukin-1β-induced late stage chondrogenic differentiation through downregulation of Wnt/β-catenin signaling pathway. Reviewed International journal

    Kazuma Miyatake, Ken Kumagai, Sosuke Imai, Yasuteru Yamaguchi, Yutaka Inaba

    PloS one   15 ( 9 )   e0239651   2020

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    Authorship：Lead author   Language：English   Publishing type：Research paper (scientific journal)  

    It is known that Wnt/β-catenin signaling induces endochondral ossification and plays a significant role in the pathophysiology of osteoarthritis (OA). Sclerostin is a potent inhibitor of the Wnt/β-catenin signaling pathway. This study investigated the role of sclerostin in the endochondral differentiation under an OA-like condition induced by proinflammatory cytokines. ATDC5 cells were used to investigate chondrogenic differentiation and terminal calcification, and 10 ng/ml IL-1β and/or 200 ng/ml sclerostin were added to the culture medium. IL-1β impaired early chondrogenesis from undifferentiated state into proliferative chondrocytes, and it was not altered by sclerostin. IL-1β induced progression of chondrogenic differentiation in the late stage and promoted terminal calcification. These processes were inhibited by sclerostin and chondrogenic phenotype was restored. In addition, sclerostin restored IL-1β-induced upregulation of Wnt/β-catenin signaling in the late stage. This study provides insights into the possible role of sclerostin in the chondrogenic differentiation under the IL-1β-induced OA-like environment. Suppression of Wnt signaling by an antagonist may play a key role in the maintenance of articular homeostasis and has a potential to prevent the progression of OA. Thus, sclerostin is a candidate treatment option for OA.

    DOI： 10.1371/journal.pone.0239651

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  • Platelet-Rich Plasma Promotes Migration, Proliferation, and the Gene Expression of Scleraxis and Vascular Endothelial Growth Factor in Paratenon-Derived Cells In Vitro

    Sosuke Imai, Ken Kumagai, Yasuteru Yamaguchi, Kazuma Miyatake, Tomoyuki Saito

    Sports Health   11 ( 2 )   142 - 148   2019.3

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    Language：English   Publishing type：Research paper (scientific journal)   Publisher：SAGE Publications Inc.  

    DOI： 10.1177/1941738118807479

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  • Sclerostin is upregulated in the early stage of chondrogenic differentiation, but not required in endochondral ossification in vitro. International journal

    Yasuteru Yamaguchi, Ken Kumagai, Sosuke Imai, Kazuma Miyatake, Tomoyuki Saito

    PloS one   13 ( 8 )   e0201839   2018

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    Sclerostin is a potent inhibitor of the canonical Wnt signaling pathway. Wnt signaling pathways have multiple roles in the regulation of cartilage development, growth, and maintenance. This study focused on the role of sclerostin in the process of chondrogenic differentiation. We hypothesized that sclerostin is essential to induce chondrogenic differentiation and regulate endochondral ossification. ATDC5 cells were used to investigate chondrogenic differentiation and terminal calcification. During chondrogenic differentiation, intrinsic sclerostin was upregulated in the early stage, but downregulated in the late stage. Addition of sclerostin elevated expressions of Sox9 and Col2a1 (P<0.05) and reduced expressions of Runx2, Col10a1, MMP-3, MMP-13, and ADAMTS5 (P<0.05) through inhibition of the Wnt-β-catenin signaling pathway (P<0.05). Terminal calcification was significantly inhibited by sclerostin (P<0.05). In contrast, deletion of sclerostin decreased expressions of Sox9 and Col2a1 (P<0.05), increased expressions of Runx2, Col10a1, MMP-3, and MMP-13 (P<0.05), and promoted terminal calcification (P<0.05). This study provides insights into the possible role of sclerostin in the regulation of chondrogenic differentiation. Sclerostin is upregulated in the early stage of chondrogenic differentiation, but is not required in endochondral ossification. Sclerostin is a candidate modulator for chondrogenic differentiation.

    DOI： 10.1371/journal.pone.0201839

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  • Effect of Low-Intensity Pulsed Ultrasound (LIPUS) on Endochondral Ossification via the Wnt Signaling Pathway. International journal

    Ken Kumagai, Yasuteru Yamaguchi, Kazuma Miyatake, Hironori Tanabe, Sosuke Imai, Tomoyuki Saito

    Journal of orthopaedic trauma   31 ( 7 )   S4-S5   2017.7

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    Language：English   Publishing type：Research paper (scientific journal)  

    OBJECTIVE: We have previously demonstrated that LIPUS stimulates endochondral ossification with decreased expression of sclerostin. The Wnt signaling pathway was examined in vitro to further address the effect of LIPUS on endochondral ossification. MATERIALS AND METHODS: ATDC5 cells were plated at an initial density of 6 × 10 cells/well in a 6-multiwell plate and cultured in the presence of 5% FBS plus ITS. The bottom of the culture plate was treated every day with LIPUS for 20 minutes. The level of calcification and the expression of Wnt signaling were investigated. RESULTS: The area of calcified nodules in the LIPUS-treated group was significantly greater than in the control group. The expression of Wnt was significantly elevated by LIPUS exposure. Markers associated with endochondral ossification were increased in the LIPUS-treated group. When sclerostin was added to the culture media, calcified nodule formation and the expression of Wnt were inhibited in both the LIPUS-treated group and the control group. DISCUSSION: This study suggests that endochondral ossification was stimulated by LIPUS via the Wnt signaling pathway.

    DOI： 10.1097/01.bot.0000520898.92470.94

    PubMed

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Presentations

  • 私のエコー活用法 肘・肩関節痛診療でのエコー活用法

    宮武 和馬, 藤澤 隆弘, 大歳 晃生, 川端 佑介, 草場 洋平, 稲葉 裕

    日本整形外科学会学術集会  2021 

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    Event date： 2021.3

    Presentation type：Symposium, workshop panel (nominated)  

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Research Projects

  • ラットの坐骨神経癒着モデルを用いた 超音波ガイド下神経剥離術の薬剤選定

    Grant number：22K16745  2022.4 - 2026.3

    日本学術振興会  科学研究費助成事業  若手研究

    宮武 和馬

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    Grant amount：\4550000 （ Direct Cost: \3500000 、 Indirect Cost：\1050000 ）

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