Updated on 2025/06/02

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写真a

 
Yasuharu Yajima
 
Organization
Graduate School of Medicine Department of Medicine Oral and Maxillofacial Surgery Assistant Professor
School of Medicine Medical Course
Title
Assistant Professor
Profile
工学分野で用いられるシミュレーションや数値流体力学などの技術を医学分野に応用し、病態メカニズムの解明、精度の高い手術や治療法の開発に取り組んでいます。
External link

Degree

  • 学士 ( 北海道大学 )

  • 博士(医学) ( 横浜市立大学 )

Research Interests

  • シミュレーション

  • 顎骨再建

  • 睡眠時無呼吸症候群

  • 上気道狭窄

  • 生体流体力学

  • 数値流体力学

  • 顎変形症

Research Areas

  • Life Science / Surgical dentistry

Education

  • Yokohama City University   Graduate School of Medicine

    - 2017.3

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    Country: Japan

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  • Hokkaido University   School of Dental Medicine

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    Country: Japan

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Research History

  • Yokohama City University   School of Medicine, Department of Oral and Maxillofacial Surgery,   Assistant Professor

    2019.4

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    Country:Japan

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  • Yokohama City University   Medical Center Oral and Maxillofacial Surgery/Orthodontics   Clinical Fellow

    2018.4 - 2019.3

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    Country:Japan

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  • The University of Tokyo   Institute of Industrial Science, Oshima Lab.   Resaerch Student

    2010.4

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    Country:Japan

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Papers

  • Computational fluid dynamics study of the pharyngeal airway space before and after mandibular setback surgery in patients with mandibular prognathism Reviewed

    Y. Yajima, M. Oshima, T. Iwai, H. Kitajima, S. Omura, I. Tohnai

    INTERNATIONAL JOURNAL OF ORAL AND MAXILLOFACIAL SURGERY   46 ( 7 )   839 - 844   2017.7

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    Language:English   Publishing type:Research paper (scientific journal)   Publisher:CHURCHILL LIVINGSTONE  

    The purpose of this study was to investigate the relationship between the pressure drop in the pharyngeal airway space (Delta P-PAS) and the minimum cross-sectional area (minCSA) of the pharyngeal airway before and after mandibular setback surgery using computational fluid dynamics, in order to prevent iatrogenic obstructive sleep apnoea. Eleven patients with mandibular prognathism underwent bilateral sagittal split osteotomy for mandibular setback. Three-dimensional models of the upper airway were reconstructed from preoperative and postoperative computed tomography images, and simulations were performed using computational fluid dynamics. Delta P-PAS and the minCSA of the pharyngeal airway were calculated, and the relationship between them was evaluated by non-linear regression analysis. In all cases, the minCSA was found at the level of the velopharynx. After surgery, Delta P-PAS increased significantly and the minCSA decreased significantly. The non-linear regression equation expressing the relationship between these variables was Delta P-PAS = 3.73 x minCSA(-2.06). When the minCSA was <1 cm(2), Delta P-PAS increased greatly. The results of this study suggest that surgeons should consider bimaxillary orthognathic surgery rather than mandibular setback surgery to prevent the development of iatrogenic obstructive sleep apnoea when correcting a skeletal class III malocclusion.

    DOI: 10.1016/j.ijom.2017.03.028

    Web of Science

    PubMed

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  • 舌下部に生じた側方型類皮嚢胞の1例

    馬場 隼一, 岩井 俊憲, 南山 周平, 杉山 聡美, 吉井 悠, 北島 大朗, 矢島 康治, 小栗 千里, 山中 正二, 光藤 健司

    横浜医学   74 ( 4 )   585 - 589   2023.11

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  • 下顎歯肉扁平上皮癌T4症例における手術療法と術前超選択的動注化学放射線療法の比較検討

    小栗 千里, 南山 周平, 北島 大朗, 矢島 康治, 大屋 貴志, 小泉 敏之, 岩井 俊憲, 來生 知, 光藤 健司

    頭頸部癌   49 ( 2 )   212 - 212   2023.5

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  • Le Fort I型骨切り時に経上顎洞底的歯根端切除術を行った大臼歯歯根嚢胞を有する顎変形症患者の1例

    本田 康二, 岩井 俊憲, 矢島 康治, 南山 周平, 村田 正人, 光藤 健司

    日本顎変形症学会雑誌   33 ( 2 )   168 - 168   2023.5

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  • ナビゲーションシステムを用いて摘出した上顎歯原性角化嚢胞再発症例

    矢谷 実英, 岩井 俊憲, 杉山 聡美, 石川 総一郎, 出田 ゆか, 吉井 悠, 南山 周平, 矢島 康治, 馬場 隼一, 小栗 千里, 光藤 健司

    横浜医学   74 ( 2 )   43 - 47   2023.4

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    歯原性角化嚢胞は歯原性上皮から生じる嚢胞性疾患の一種であり,高い浸潤性や再発傾向など腫瘍に類似した性格を特徴とする.外科的治療が唯一の治療法であり,摘出術を第一選択とするが,多発再発例や後方進展例は根治性の確保のため顎骨切除が考慮されうる.今回われわれはナビゲーションシステムを用いて摘出術を行い顎骨温存を可能とした上顎歯原性角化嚢胞再発症例について報告する.症例は57歳の男性,前医で上顎骨嚢胞の診断で摘出術を受けた.病理検査にて歯原性角化嚢胞と診断され,術後2年の画像検査で眼窩底近傍および口蓋骨錐体突起部に多発再発を認めた.顎骨切除が提案されたが,顎骨温存を希望し当科紹介された.再発病変が上顎骨内深部に存在し重要臓器に近接していたことから,病変のリアルタイムでの位置評価のためナビゲーションシステムを用いた嚢胞摘出術が実施された.術中ナビゲーションは三次元的な病変の同定を正確かつ安全に可能とし,嚢胞摘出術と周囲骨の削除は周辺臓器や神経血管束の損傷なしに行われた.術後合併症もなく経過は良好で,術後14か月経過した時点での骨形成は良好で病変の再発は認めなかった.(著者抄録)

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  • ナビゲーションシステムを用いて摘出した上顎歯原性角化嚢胞再発症例

    矢谷 実英, 岩井 俊憲, 杉山 聡美, 石川 総一郎, 出田 ゆか, 吉井 悠, 南山 周平, 矢島 康治, 馬場 隼一, 小栗 千里, 光藤 健司

    横浜医学   74 ( 2 )   43 - 47   2023.4

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    Language:Japanese   Publisher:横浜市立大学医学会  

    歯原性角化嚢胞は歯原性上皮から生じる嚢胞性疾患の一種であり,高い浸潤性や再発傾向など腫瘍に類似した性格を特徴とする.外科的治療が唯一の治療法であり,摘出術を第一選択とするが,多発再発例や後方進展例は根治性の確保のため顎骨切除が考慮されうる.今回われわれはナビゲーションシステムを用いて摘出術を行い顎骨温存を可能とした上顎歯原性角化嚢胞再発症例について報告する.症例は57歳の男性,前医で上顎骨嚢胞の診断で摘出術を受けた.病理検査にて歯原性角化嚢胞と診断され,術後2年の画像検査で眼窩底近傍および口蓋骨錐体突起部に多発再発を認めた.顎骨切除が提案されたが,顎骨温存を希望し当科紹介された.再発病変が上顎骨内深部に存在し重要臓器に近接していたことから,病変のリアルタイムでの位置評価のためナビゲーションシステムを用いた嚢胞摘出術が実施された.術中ナビゲーションは三次元的な病変の同定を正確かつ安全に可能とし,嚢胞摘出術と周囲骨の削除は周辺臓器や神経血管束の損傷なしに行われた.術後合併症もなく経過は良好で,術後14か月経過した時点での骨形成は良好で病変の再発は認めなかった.(著者抄録)

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  • 舌癌に対する逆行性超選択的動注化学放射線療法の治療効果と食事摂取状況の評価

    大屋 貴志, 陳 雪霏, 石川 聡一郎, 南山 周平, 矢島 康治, 小栗 千里, 小泉 敏之, 岩井 俊憲, 來生 知, 光藤 健司

    日本口腔科学会雑誌   71 ( 4 )   224 - 224   2022.12

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  • 巨舌による閉塞性睡眠時無呼吸に対し舌縮小術を施行した1例

    矢島 康治, 出田 ゆか, 小栗 千里, 小泉 敏之, 岩井 俊憲, 來生 知, 光藤 健司

    睡眠口腔医学   9 ( 総会特別号 )   111 - 111   2022.10

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    Language:Japanese   Publisher:(NPO)日本睡眠歯科学会  

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  • 閉塞性睡眠時無呼吸に対する口腔内装置の治療効果についての流体力学的検討

    矢島 康治, 杉山 聡美, 岩井 俊憲, 小栗 千里, 小泉 敏之, 來生 知, 光藤 健司

    日本口腔科学会雑誌   71 ( 2 )   146 - 147   2022.7

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  • ナビゲーションシステムと二分割サージカルガイドを用いて骨削除術を行った下顎骨線維性異形成症の1例

    矢島 康治, 岩井 俊憲, 本田 康二, 杉山 聡美, 石川 聡一郎, 出田 ゆか, 矢谷 実英, 南山 周平, 馬場 隼一, 大橋 伸英, 片岡 俊朗, 藤井 誠志, 光藤 健司

    横浜医学   73 ( 2 )   47 - 53   2022.6

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  • ナビゲーションシステムと二分割サージカルガイドを用いて骨削除術を行った下顎骨線維性異形成症の1例

    矢島 康治, 岩井 俊憲, 本田 康二, 杉山 聡美, 石川 聡一郎, 出田 ゆか, 矢谷 実英, 南山 周平, 馬場 隼一, 大橋 伸英, 片岡 俊朗, 藤井 誠志, 光藤 健司

    横浜医学   73 ( 2 )   47 - 53   2022.6

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    線維性異形成症(Fibrous dysplasia:FD)は,幼若な骨形成を伴う線維組織の増殖性病変であり,骨膨隆を引き起こす.下顎骨に発症した場合,非対称な顔貌となり治療は骨削除術が行われるが,口腔内の手術は視野や器具の制限により術後に十分な顔面の対称性が得られないことが多い.そこで,われわれは下顎FDに対して骨削除量を決めるサージカルガイドを作製し,ナビゲーションシステムと併用した手術を行った.症例は28歳女性で,左側下顎部の腫脹を主訴に当科紹介初診となった.CT画像より3次元(3D)画像ソフトウェアにて下顎骨を3D構築し,正中矢状面に対し健側をミラーリングした下顎骨を基準に3mm余剰に骨削除を行う方針とした.下顎枝後縁と下顎下縁の切除するサージカルガイドをソフトウェア内で設計し,オトガイ神経を避けて口腔内に挿入できるように二分割した状態で3Dプリンターを用いて作製した.下顎骨外側の骨削除は,ナビゲーションシステムにて確認しながら骨削除を行った.下顎骨にサージカルガイドを装着し,下縁と後縁の切除を行った.術後撮影したCTと重ね合わせを行ったところ,ミラーリングした下顎骨より概ね3mm余剰に骨削除が行われており,下顎管の損傷はなかった.ナビゲーションシステムにサージカルガイドを併用することで,手術の簡便化が可能となり,骨削除のオーバーコレクションにより対称な顔貌形態を獲得できた.(著者抄録)

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    Other Link: https://search.jamas.or.jp/default/link?pub_year=2022&ichushi_jid=J01499&link_issn=&doc_id=20220719350004&doc_link_id=http%3A%2F%2Fid.nii.ac.jp%2F1246%2F00002351%2F&url=http%3A%2F%2Fid.nii.ac.jp%2F1246%2F00002351%2F&type=%E6%A8%AA%E6%B5%9C%E5%B8%82%E7%AB%8B%E5%A4%A7%E5%AD%A6%EF%BC%9A%E6%A8%AA%E6%B5%9C%E5%B8%82%E7%AB%8B%E5%A4%A7%E5%AD%A6%E5%AD%A6%E8%A1%93%E6%A9%9F%E9%96%A2%E3%83%AA%E3%83%9D%E3%82%B8%E3%83%88%E3%83%AA&icon=https%3A%2F%2Fjk04.jamas.or.jp%2Ficon%2F80205_3.gif

  • 局所進行下顎歯肉癌における下顎骨離断症例に対する下唇非切開による原発切除の検討

    小栗 千里, 南山 周平, 大屋 貴志, 矢島 康治, 岩井 俊憲, 小泉 敏之, 來生 知, 光藤 健司

    頭頸部癌   48 ( 2 )   216 - 216   2022.5

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  • 両側下顎枝矢状分割後のプレート破折の検討

    南山 周平, 岩井 俊憲, 矢島 康治, 本田 康二, 光藤 健司

    日本顎変形症学会雑誌   32 ( 2 )   193 - 193   2022.5

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  • 成人に生じた顎下部リンパ管奇形の1例

    南山 周平, 岩井 俊憲, 杉山 聡美, 石川 聡一郎, 出田 ゆか, 吉井 悠, 矢島 康治, 馬場 隼一, 小栗 千里, 光藤 健司

    日本口腔診断学会雑誌   35 ( 1 )   29 - 34   2022.2

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    症例は31歳男性で、左側顎下部の腫脹を主訴とした。他院にて顎下型ラヌーラの診断で約10年間OK-432の局注療法を受けたが改善しなかった。腫瘤は弾性軟で無痛性であり、CTでは多房性嚢胞状病変が左側顎下腺の後方かつ広頸筋の内側から胸鎖乳突筋の内側まで進展し、MRIではT2強調像で高信号を呈していた。超音波ガイド下穿刺吸引では淡黄色で漿液性の内容液を認め、リンパ管奇形と診断した。全身麻酔下に病変を一塊に摘出し、病理組織学的にもリンパ管奇形と診断された。術後に神経麻痺は認めず軽快退院し、5年以上経過して再発は認めず経過良好である。

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  • Bartter症候群を伴う下顎前突症患者の下顎形成手術における周術期管理の経験

    大澤 昂平, 岡本 喜之, 柳田 健, 杉浦 圭, 矢島 康治, 光藤 健司

    日本口腔科学会雑誌   70 ( 3 )   267 - 272   2021.9

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    Bartter症候群は低カリウム血症を特徴とするまれな疾患である。われわれはBartter症候群患者の周術期管理を経験したので報告する。不正咬合を主訴にBartter症候群の18歳の女性が当院を受診した。下顎前突症のため術前矯正後、全身麻酔下で下顎形成術を施行した。周術期に低カリウム血症を発症する可能性があったため、担当医師に相談し、手術開始時からカリウム投与を開始した。その結果、周術期に低カリウム血症を発症せず、全身状態は良好であった。(著者抄録)

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  • 急性炎症により導管から逸脱した耳下腺唾石症の1例

    上田 潤, 岩井 俊憲, 杉山 聡美, 大橋 伸英, 矢島 康治, 馬場 隼一, 小栗 千里, 佐久間 要, 戸谷 収二, 光藤 健司

    日本口腔診断学会雑誌   34 ( 1 )   20 - 24   2021.2

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    症例は49歳男性で、左側頬部に疼痛を伴う強い腫脹を認めたため、他院耳鼻咽喉科・頭頸部外科を受診した。CTなどの画像検査が行われ、左側耳下腺唾石症および急性化膿性耳下腺炎と診断された後、抗菌薬の投与が行われた。消炎治療後、内視鏡下での低侵襲な治療を希望され当科紹介受診となった。反復する炎症により、初診時点ですでに唾石が導管外に逸脱していた可能性を考慮し、手術はまず唾液腺内視鏡で導管内を観察し、唾石が導管外に逸脱している場合には皮膚自壊部を切開して口外法で唾石摘出する方針とした。術中所見より唾石が導管内の肉芽形成部より導管外に逸脱したものと考え、口外法での唾石摘出術に切りかえた。術後2ヵ月目には皮膚の炎症症状は完全に消失し、左側耳下腺開口部より良好な唾液の流出が認められた。

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  • A Case of Submandibular Lymphatic Malformation in an Adult

    SHUHEI MINAMIYAMA, TOSHINORI IWAI, SATOMI SUGIYAMA, SOICHIRO ISHIKAWA, YUKA IDETA, HARUKA YOSHII, YASUHARU YAJIMA, JUNICHI BABA, SENRI OGURI, KENJI MITSUDO

    Japanese Journal of Oral Diagnosis / Oral Medicine   35 ( 1 )   29 - 34   2021

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    DOI: 10.15214/jsodom.35.29

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  • A Case of Extraductal Parotid Gland Stone Caused by Repeated Inflammation

    JUN UEDA, TOSHINORI IWAI, SATOMI SUGIYAMA, NOBUHIDE OHASHI, YASUHARU YAJIMA, JUNICHI BABA, SENRI OGURI, KANAME SAKUMA, SHUJI TOYA, KENJI MITSUDO

    Japanese Journal of Oral Diagnosis / Oral Medicine   34 ( 1 )   20 - 24   2021

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    DOI: 10.15214/jsodom.34.20

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  • A Case of Submental Type of Giant Dermoid Cysts Develop in the Sublingual Area

    ATSUSHI TAKEDA, YOSUKE YAMASHITA, KAREN GOMI, NOBUHIDE OHASHI, SHUHEI MINAMIYAMA, YASUHARU YAJIMA, KEI SUGIURA, JUNICHI BABA, HIKARU TAKASU, KENJI MITSUDO

    Japanese Journal of Oral Diagnosis / Oral Medicine   35 ( 1 )   41 - 45   2021

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    DOI: 10.15214/jsodom.35.41

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  • Image-guided removal of deeply impacted mandibular third molar using a navigation system Reviewed

    Atsushi Takeda, Toshinori Iwai, Satomi Sugiyama, Nobuhide Ohashi, Hiroaki Kitajima, Yasuharu Yajima, Makoto Hirota, Kenji Mitsudo

    Journal of Oral and Maxillofacial Surgery, Medicine, and Pathology   32 ( 6 )   529 - 533   2020.11

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    © 2020 Asian AOMS(+) ASOMP(+) JSOP(+) JSOMS(+) JSOM(+) and JAMI Conventional intraoral removal of deeply impacted or ectopic mandibular third molar is challenging for limited surgical access. Because there are potential risks of inferior alveolar nerve (IAN) injury or iatrogenic mandibular fracture, several methods for the removal have been proposed. As minimally invasive and safe surgery, we report image-guided removal of deeply impacted mandibular third molar using navigation system. A 32-year-old male was referred to our department with right mandibular pain and swelling. Panoramic radiograph showed right mandibular third molar was deeply impacted and interrupted the white line of the mandibular canal. Computed tomography (CT) showed deep impacted right mandibular third molar with root projection from the lingual cortical bone, and there was resorption of lingual cortical bone and passing of mandibular nerve between roots. For mandibular navigation surgery, a resin occlusal splint with titanium markers and handle was manufactured to fix reference frame to the mandible. CT was performed preoperatively after the occlusal splint was fixed with patient's mandibular teeth, and the patient underwent image-guided removal of mandibular third molar with navigation system under general anesthesia. After reference frame was attached to the handle of the occlusal splint fixed with patient's mandibular teeth, point-based registration was performed. The crown was removed after the sectioning, and the root sectioning with calibrated bur was performed carefully to avoid injury of the IAN under navigational guidance. The roots were completely removed, and the IAN was exposed in the lingual cortical bone defect. Postoperative course was uneventful without paresthesia of the IAN.

    DOI: 10.1016/j.ajoms.2020.07.012

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  • Computational Fluid Dynamics Study of Superselective Intra-arterial Chemotherapy for Oral Cancer: Flow Simulation of Anticancer Agent in the Linguofacial Trunk Reviewed

    Hiroaki Kitajima, Toshinori Iwai, Yasuharu Yajima, Kenji Mitsudo

    APPLIED SCIENCES-BASEL   10 ( 21 )   2020.11

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    Superselective intra-arterial chemotherapy (SSIAC) for oral cancer can deliver a higher concentration of anticancer agent into a tumor-feeding artery than intravenous systemic chemotherapy. However, the agent distribution between the lingual artery and facial artery (FA) is not clear in SSIAC for patients with the linguofacial trunk. The agent distribution in the SSIAC method was investigated using computational fluid dynamics (CFD). Ten three-dimensional vessel models were created from CT images of two patients with oral cancer (patients A and B) with the linguofacial trunk. Catheter models were combined with vessel models to mimic intra-arterial infusion, and the agent flow was analyzed. In patient A models, the agent distribution varied depending on the catheter tip position in the linguofacial trunk, while all anticancer agents flowed into the FA only in patient B models. This study revealed that the behavior of the agent in the common trunk is determined by the blood flow field which depends on the topography of the vessels in each patient. Therefore, the catheter tip position should be changed according to the vessel topography to deliver anticancer agents into the tumor-feeding artery. Moreover, CFD can be a useful method to predict the agent flow for each patient before SSIAC.

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  • Computational Fluid Simulation of Fibrinogen around Dental Implant Surfaces. International journal

    Hiroaki Kitajima, Makoto Hirota, Toshinori Iwai, Kosuke Hamajima, Ryotaro Ozawa, Yuichiro Hayashi, Yasuharu Yajima, Masaki Iida, Toshiyuki Koizumi, Mitomu Kioi, Kenji Mitsudo, Takahiro Ogawa

    International journal of molecular sciences   21 ( 2 )   2020.1

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    Ultraviolet treatment of titanium implants makes their surfaces hydrophilic and enhances osseointegration. However, the mechanism is not fully understood. This study hypothesizes that the recruitment of fibrinogen, a critical molecule for blood clot formation and wound healing, is influenced by the degrees of hydrophilicity/hydrophobicity of the implant surfaces. Computational fluid dynamics (CFD) implant models were created for fluid flow simulation. The hydrophilicity level was expressed by the contact angle between the implant surface and blood plasma, ranging from 5° (superhydrophilic), 30° (hydrophilic) to 50° and 70° (hydrophobic), and 100° (hydrorepellent). The mass of fibrinogen flowing into the implant interfacial zone (fibrinogen infiltration) increased in a time dependent manner, with a steeper slope for surfaces with greater hydrophilicity. The mass of blood plasma absorbed into the interfacial zone (blood plasma infiltration) was also promoted by the hydrophilic surfaces but it was rapid and non-time-dependent. There was no linear correlation between the fibrinogen infiltration rate and the blood plasma infiltration rate. These results suggest that hydrophilic implant surfaces promote both fibrinogen and blood plasma infiltration to their interface. However, the infiltration of the two components were not proportional, implying a selectively enhanced recruitment of fibrinogen by hydrophilic implant surfaces.

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  • Computational fluid simulation of fibrinogen around dental implant surfaces Reviewed

    Kitajima H, Hirota M, Iwai T, Hamajima K, Ozawa R, Hayashi Y, Yajima Y, Iida M, Koizumi T, Kioi M, Mitsudo K, Ogawa T

    Int J Mol Sci   21 ( 2 )   E660   2020.1

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  • Accuracy of mandible-independent maxillary repositioning using pre-bent locking plates: a pilot study Reviewed

    Imai H, Fujita K, Yamashita Y, Yajima Y, Takasu H, Takeda A, Honda K, Iwai T, Mitsudo K, Omura S

    Int J Oral Maxillofac Surg   2020

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  • ナビゲーションシステムを用いて形成術を施行した上顎線維性異形成症の1例

    杉山 聡美, 岩井 俊憲, 大橋 伸英, 矢島 康治, 大澤 孝行, 藤内 祝

    日本口腔外科学会雑誌   64 ( 10 )   618 - 623   2018.10

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    症例は23歳男性で、18歳時に右側鼻腔の狭小化と右上顎の膨隆を指摘され、生検での結果Fibrous dysplasiaと診断された。経過観察されていたが、徐々に上顎が膨隆し顔貌の非対称が強くなったため手術が必要と判断された。手術は、右側上顎の膨隆した骨を顔面の対称性が得られるように削除するために、ナビゲーションシステムを用いた形成術を計画した。上顎右2近心に縦切開を行い、上顎右7まで歯肉縁切開を行った。その後、骨膜下を剥離し、膨隆した上顎骨を明示した。ナビゲーションガイド下にミラーリング像を指標にしながら、膨隆した骨にミラー像の深さまでグループを入れた後に、グループをつなげるようにラウンドバーで骨の削除を行った。術中、患者頭部に固定したリファレンスに助手が触れたことでナビゲーョンの誤差が生じたため、オクルーザルスプリントを両度装着し、再レジストレーションを行った。ナビゲーションの誤差が1mm以内になった後、手術を再開した。その後、プローブで骨削除断端部を触れることで、計画通りの骨削除が行えているかナビゲーションシステムのモニター上で確認しながら、十分な骨削除量が得られるまで手術を行った。術後経過は良好であり、術後9年経過するも左右対称な顔貌が得られている。

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  • Computational fluid dynamics study of intra-arterial chemotherapy for oral cancer Reviewed

    Hiroaki Kitajima, Marie Oshima, Toshinori Iwai, Yoshihito Ohhara, Yasuharu Yajima, Kenji Mitsudo, Iwai Tohnai

    BIOMEDICAL ENGINEERING ONLINE   16   2017.5

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    Background: Intra-arterial chemotherapy (IAC) for oral cancer can deliver a higher concentration of anticancer agent into a tumor-feeding artery than intravenous systemic chemotherapy. However, distribution of anticancer agent into several branches of the external carotid artery (ECA) in IAC has not demonstrated sufficient treatment efficacy. To improve the effectiveness of IAC, the flow distribution of anticancer agent into the branches of the ECA in several IAC methods was investigated using computational fluid dynamics (CFD).
    Methods: Patient-specific three-dimensional vessel models were created from CT images of 2 patients with tongue cancer. Catheter models were combined with the vessel models. Thirty-two models were generated with varying vertical and horizontal positions of the catheter tip. With the use of a zero-dimensional resistance model of the peripheral vessel network, conventional IAC and superselective IAC were simulated in 30 and 2 models, respectively. The flow distribution of anticancer agent into the branches of the ECA was investigated in 32 models. Additionally, the blood streamline was traced from the inlet of the common carotid artery toward each outlet to examine the flow of anticancer agent in all models, and the wall shear stress of the vessel was calculated for some models.
    Results: The CFD simulations could be conducted within a reasonable computational time. In several models, the anticancer agent flowed into the target artery only when the catheter tip was located below the bifurcation of the ECA and each target artery. Furthermore, the anticancer agent tended to flow into the target artery when the catheter tip was shifted toward the target artery. In all ECA branches that had flow of anticancer agent, the blood streamlines to the target arteries contacted the catheter tip. Anticancer agent flowed into only the target artery in patients' models for superselective IAC. However, high wall shear stress was observed at the target artery in one patient's model.
    Conclusions: This CFD study showed that location of the catheter tip was important in controlling the anticancer agent in conventional IAC. The distribution rate of anticancer agent into the tumor-feeding artery tended to increase when the catheter tip was placed below and toward the target artery. Although superselective IAC can reliably supply anticancer agent to the target artery, high wall shear stress at the target artery can occur, depending on vessel geometry of the patient, which may cause serious complications during the treatment.

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  • Use of eXtensible Virtual Word Description Language (XVL) File to Embed Simply and User-friendly Three-Dimensional Medical Data for PowerPoint Presentation Reviewed

    Tomoki Itamiya, Toshinori Iwai, Yasuharu Yajima, Tsuyoshi Kaneko

    JOURNAL OF CRANIOFACIAL SURGERY   28 ( 1 )   298 - 299   2017.1

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  • A Case of Granular Cell Tumor Arising at the Zygomatic Region

    OKAMOTO YOSHIYUKI, ISHIKAWA YOSHIMI, YAMAMOTO MANABU, MIYAMOTO MASAYUKI, YAJIMA YASUHARU, NAKASHIMA HIDEYUKI, BABA JUN-ICHI, OHASHI NOBUHIDE, IWAI TOSHINORI, TOHNAI IWAI

    Japanese Journal of Oral Diagnosis / Oral Medicine   30 ( 1 )   60 - 64   2017

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    Granular cell tumors are rare soft tissue tumors, derived from Schwann cells. About half of them occur in the head and neck, but a case with tumor arising in the zygomatic region has not been reported to our knowledge. We report a case of granular cell tumor arising in the zygomatic region. A 57-year-old woman was referred to our hospital because of cheek swelling. MRI findings showed a benign tumor, so the patient wished follow-up. However, the tumor gradually grew in size for 11 months, as was confirmed by MRI. Since the patient desired removal of the tumor, the operation was performed by the intraoral and subcilial approach. The histopathological diagnosis was granular cell tumor. Judging from the operative finding, we supposed the origin of the tumor to be the zygomaticofacial nerve which is a branch of the maxillary nerve. Twenty-six months after the operation, there was no sign of recurrence.

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  • Investigation of blood flow in the external carotid artery and its branches with a new 0D peripheral model Reviewed

    Yoshihito Ohhara, Marie Oshima, Toshinori Iwai, Hiroaki Kitajima, Yasuharu Yajima, Kenji Mitsudo, Absy Krdy, Iwai Tohnai

    BIOMEDICAL ENGINEERING ONLINE   15   2016.2

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    Background: Patient-specific modelling in clinical studies requires a realistic simulation to be performed within a reasonable computational time. The aim of this study was to develop simple but realistic outflow boundary conditions for patient-specific blood flow simulation which can be used to clarify the distribution of the anticancer agent in intra-arterial chemotherapy for oral cancer.
    Methods: In this study, the boundary conditions are expressed as a zero dimension (0D) resistance model of the peripheral vessel network based on the fractal characteristics of branching arteries combined with knowledge of the circulatory system and the energy minimization principle. This resistance model was applied to four patient-specific blood flow simulations at the region where the common carotid artery bifurcates into the internal and external carotid arteries.
    Results: Results of these simulations with the proposed boundary conditions were compared with the results of ultrasound measurements for the same patients. The pressure was found to be within the physiological range. The difference in velocity in the superficial temporal artery results in an error of 5.21 +/- 0.78 % between the numerical results and the measurement data.
    Conclusions: The proposed outflow boundary conditions, therefore, constitute a simple resistance-based model and can be used for performing accurate simulations with commercial fluid dynamics software.

    DOI: 10.1186/s12938-016-0133-x

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  • Computational fluid dynamics study on the nasal respiratory function before/after maxillo-mandibular orthognathic surgery

    KITA Soma, SHIMAZAKI Kazuo, YAJIMA Yasuharu, OMURA Susumu, ONO Takashi, OSHIMA Marie

    SEISAN KENKYU   67 ( 1 )   55 - 58   2015

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    The influence that maxillary movement gives for breathing is great, and it needs a functional evaluation. But there is not the report about stenosis of the nasal cavity with the maxillary bone upward movement. Therefore we analyzed it for the purpose of clarifying the influence that maxillo-mandibular orthognathic surgery with the maxillary bone upward movement gave for a nose breathing function.<br>By moving maxillary bone above and resecting inferior border of the pyriform aperture, the pressure drop of the nasal cavity got a result to decrease after surgery. Furthermore, it was recognized that a lot of pressure drop occurred in nasal cavity front 1/3, and the possibility that resecting inferior border of the pyriform aperture was useful from the viewpoint of nasal cavity ventilation was suggested.

    DOI: 10.11188/seisankenkyu.67.55

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  • Screening of upper gastrointestinal synchronous double cancer in patients with oral cancer:A comparison between upper gastrointestinal fiberscopy and <sup>18</sup>F-FDG-PET/CT

    Iwai Toshinori, Shibasaki Maiko, Kitajima Hiroaki, Yajima Yasuharu, Nakashima Hideyuki, Oguri Senri, Hirota Makoto, Mitsudo Kenji, Tohnai Iwai

    Journal of Japanese Society of Oral Oncology   26 ( 2 )   31 - 36   2014

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    We report a comparison between upper gastrointestinal fiberscopy (GIF) and <sup>18</sup>F-fluorodeoxyglucose positron emission tomography/computed tomography (FDG-PET/CT) for screening of upper gastrointestinal double cancer in patients with oral cancer.<br>Between September 2006 and August 2009, 133 patients with oral cancer underwent GIF and FDG-PET/CT before treatment. Five patients (3.8%) had synchronous double cancer in the esophagus or stomach using GIF. There were early-stage cancers in all cases. However, FDG-PET/CT could detect double cancer (esophageal cancer) in only one patient, and the sensitivity and specificity were 20% and 100%, respectively. This study proved the usefulness and necessity of GIF for screening in the upper gastrointestinal regions before treatment in patients with oral cancer.

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  • Cervicofacial subcutaneous emphysema associated with dental laser treatment Reviewed

    S. Mitsunaga, T. Iwai, H. Kitajima, Y. Yajima, T. Ohya, M. Hirota, K. Mitsudo, N. Aoki, Y. Yamashita, S. Omura, I. Tohnai

    AUSTRALIAN DENTAL JOURNAL   58 ( 4 )   424 - 427   2013.12

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    Cervicofacial subcutaneous emphysema is a rare complication of dental procedures. Although most cases of emphysema occur incidentally with the use of a high-speed air turbine handpiece, there have been some reports over the past decade of cases caused by dental laser treatment. Emphysema as a complication caused by the air cooling spray of a dental laser is not well known, even though dental lasers utilize compressed air just as air turbines and syringes do. In this study, we comprehensively reviewed cases of emphysema attributed to dental laser treatment that appeared in the literature between January 2001 and September 2012, and we included three such cases referred to us. Among 13 cases identified in total, nine had cervicofacial subcutaneous and mediastinal emphysema. Compared with past reviews, the incidence of mediastinal emphysema caused by dental laser treatment was higher than emphysema caused by dental procedure without dental laser use. Eight patients underwent CO2 laser treatment and two underwent Er:YAG laser treatment. Nine patients had emphysema following laser irradiation for soft tissue incision. Dentists and oral surgeons should be cognizant of the potential risk for iatrogenic emphysema caused by the air cooling spray during dental laser treatment and ensure proper usage of lasers.

    DOI: 10.1111/adj.12119

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  • Computer-assisted preoperative simulation for screw fixation of fractures of the condylar head Reviewed

    Toshinori Iwai, Yasuharu Yajima, Yoshiro Matsui, Iwai Tohnai

    British Journal of Oral and Maxillofacial Surgery   51 ( 2 )   176 - 177   2013

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    Language:English   Publishing type:Research paper (scientific journal)   Publisher:Churchill Livingstone  

    DOI: 10.1016/j.bjoms.2012.03.021

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  • Experience of Tracheal Tube Fixation Through the Retromolar Space in Patients with Maxillofacial Fractures

    IWAI TOSHINORI, MAEGAWA JIRO, YASUMURA KAZUNORI, YAJIMA YASUHARU, SHIBASAKI MAIKO, BABA JUNICHI, OHYA TAKASHI, OHHARA YOSHIHITO, TOHNAI IWAI

    日本口腔診断学会雑誌   25 ( 1 )   19 - 21   2012.2

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  • A Case of Ultrasound-guided Intraoral Removal of Sialolithiasis in the Parotid Duct

    YAMASHITA YOSUKE, IWAI TOSHINORI, MASUDA GENZABURO, YAJIMA YASUHARU, SHIBASAKI MAIKO, OHYA TAKASHI, OHHARA YOSHIHITO, AOKI NORIAKI, TOHNAI IWAI

    24 ( 3 )   384 - 388   2011.10

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  • Two Cases of Removal of Deeply Impacted Mandibular Molars using Buccal Corticotomy

    IWAI TOSHINORI, OMURA SUSUMU, KIMIZUKA SACHIKO, AOKI NORIAKI, YAMASHITA YOSUKE, YAJIMA YASUHARU, MATSUI YOSHIRO, TOHNAI IWAI

    24 ( 3 )   413 - 418   2011.10

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  • Endoscopically-assisted Fixation with Biodegradable Plate for Condylar Base Fracture of the Mandible : A Case Report

    IWAI TOSHINORI, MAEGAWA JIRO, YASUMURA KAZUNORI, OHHARA YOSHIHITO, SHIBASAKI MAIKO, OHYA TAKASHI, YAJIMA YASUHARU, MATSUI YOSHIRO, TOHNAI IWAI

    24 ( 3 )   402 - 406   2011.10

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  • A Case of Navigation Aided Surgery for Facial Asymmetry after Treatment of Orbitozygomatic Fracture

    IWAI TOSHINORI, MAEGAWA JIRO, YASUMURA KAZUNORI, OHHARA YOSHIHITO, OHYA TAKASHI, SHIBASAKI MAIKO, YAJIMA YASUHARU, MATSUI YOSHIRO, TOHNAI IWAI

    24 ( 3 )   407 - 412   2011.10

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  • A case of cancer of the oral floor (T4aN3M0) treated successfully with thermochemoradiotherapy

    SHIBASAKI Maiko, MITSUDO Kenji, IWAI Toshinori, YAJIMA Yasuharu, OHYA Takashi, OHHARA Yoshihito, MITSUNAGA Sachiyo, HIROTA Makoto, TOHNAI Iwai

    Journal of Japanese Society of Oral Oncology   23 ( 1 )   9 - 15   2011.3

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    We report a case of cancer of the oral floor (T4aN3M0) treated successfully with thermochemoradiotherapy.<br>A male in his 60's with a mass in the oral floor was referred to our department. There was a tumor in the oral floor measuring 40 &times; 35 mm and left cervical swelling. CT images showed that the tumor had invaded extrinsic tongue muscles and its size was 42 &times; 35 &times; 30 mm, and there were also large metastatic lymph nodes from level II to IV. After the biopsy, the patient was diagnosed as squamous cell carcinoma of the oral floor (T4aN3M0). As the patient wanted to preserve oral function and refused to undergo operation of the primary site excluding neck dissection, we performed superselective intra-arterial chemotherapy via bilateral superficial temporal arteries (cisplatin: total 264 mg, docetaxel: total 144 mg) with daily concurrent radiotherapy (1.8 Gy/day, total 59.4 Gy) and thermoradiotherapy for cervical lymph node metastases (RF capacitive hyperthermia: twice). After the treatments, the primary and cervical sites became remarkably small. Although the treatment effect was complete response of the primary tumor and cervical lymph node metastases 6 weeks after the treatment, CT images revealed lung metastasis. The patient died 20 months after the initial treatments in spite of chemotherapy. During follow-up, there was no recurrence of the primary tumor or cervical lymph node metastases.

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  • A case with carcinoma of the upper gingiva and N3 treated successfully with retrograde superselective intra-arterial chemoradiotherapy combined with hyperthermia

    MITSUNAGA Sachiyo, MITSUDO Kenji, IWAI Toshinori, YAJIMA Yasuharu, SHIBASAKI Maiko, OHYA Takashi, OHHARA Yoshihito, HIROTA Makoto, TOHNAI Iwai

    Journal of Japanese Society of Oral Oncology   22 ( 4 )   157 - 163   2010.12

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    We report a case with carcinoma of the upper gingiva and N3 treated successfully with retrograde superselective intra-arterial chemoradiotherapy combined with hyperthermia.<br>A 39-year-old male with swelling of the left cervical region was referred to our department. The mass was 65 &times; 55 mm. The tumor was diagnosed as squamous cell carcinoma of the upper gingiva and cervical lymph node metastasis (T2N3M0) by radiological and pathological diagnosis. The patient underwent chemoradiotherapy using superselective intra-arterial infusion via the superficial temporal artery and occipital artery combined with hyperthermia. The total dose of cisplatin was 150 mg/m<sup>2</sup>, and that of docetaxel was 60 mg/m<sup>2</sup>. External irradiation was performed five times a week at 2 Gy per fraction, for a total of 60 Gy. Hyperthermia was performed 5 times for 6 weeks.<br>Pathological complete response was achieved in the primary site 1 month after the completion of the treatment. However, the clinical effect of the lymph node was partial response. Therefore, the patient underwent bilateral neck dissections and soft tissue reconstruction. The pathological diagnosis of the resected lymph node was complete response. The patient has been free of disease for 20 months. This method may be an effective treatment for cervical lymph node metastasis, N3.

    DOI: 10.5843/jsot.22.157

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  • 歯科発アクティブライフプロモーション21 : 健康増進からフレイル予防まで

    花田, 信弘, 武内, 博朗, 野村, 義明, 泉福, 英信( Role: Contributor休養阻害因子である睡眠時無呼吸症候群に対する診療.164-167)

    デンタルダイヤモンド社  2017.4  ( ISBN:9784885103711

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  • Sleep Apnea Syndrome

    Yasuharu Yajima( Role: ContributorThe Quintessence 34(3):508-520)

    Quintessence Publishing  2015.3 

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  • 全身麻酔後の気道閉塞・心肺停止から蘇生できた未診断の閉塞性睡眠時無呼吸患者の1例

    四戸希久世, 矢島康治, 岩井俊憲, 杉山聡美, 石川聡一郎, 吉井悠, 林雄一郎, 大橋伸英, 小栗千里, 光藤健司

    日本口腔科学会雑誌(Web)   72 ( 4 )   2023

  • Two cases using CAD/CAM osteotomy guide for genioplasty

    本田康二, 岩井俊憲, 矢島康治, 南山周平, 藤田紘一, 藤田紘一, 今井治樹, 今井治樹, 米満郁男, 小野卓史, 廣田誠, 光藤健司

    日本顎変形症学会雑誌   32 ( 2 )   2022

  • 下顎歯肉癌の下顎骨離断症例における下唇非切開による原発切除の検討

    小栗 千里, 矢谷 実英, 杉山 聡美, 小杉 泰史, 林 雄一郎, 大橋 伸英, 馬場 隼一, 矢島 康治, 大屋 貴志, 岩井 俊憲, 小泉 敏之, 來生 知, 光藤 健司

    頭頸部癌   46 ( 2 )   194 - 194   2020.7

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  • CAD/CAM暫間固定ガイドを用いた新しい上顎位置決め法の精度評価

    本田 康二, 岩井 俊憲, 杉山 聡美, 林 雄一郎, 矢島 康治, 藤田 紘一, 今井 治樹, 米満 郁男, 島崎 一夫, 小野 卓史, 廣田 誠, 光藤 健司

    日本顎変形症学会雑誌   30 ( 2 )   151 - 151   2020.5

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  • 局所進行下顎歯肉癌の下顎離断症例に対する下唇非切開による原発切除の検討

    小栗千里, 矢谷実英, 渡辺大智, 杉山聡美, 小杉泰史, 林雄一郎, 大橋伸英, 馬場隼一, 矢島康治, 大屋貴志, 飯田昌樹, 岩井俊憲, 小泉敏之, 來生知, 光藤健司

    日本口腔腫瘍学会総会・学術大会プログラム・抄録集   38th   2020

  • オステオトミーガイド、プレベンドプレートを用いた頭蓋基準の上顎位置決め法の正確度

    今井 治樹, 大村 進, 藤田 紘一, 山下 陽介, 高須 曜, 竹田 敦, 矢島 康治, 本田 康二, 岩井 俊憲, 小野 卓史, 廣田 誠, 光藤 健司

    日本顎変形症学会雑誌   29 ( 2 )   222 - 222   2019.5

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  • オステオトミーガイド、プレベンドプレートを用いた下顎枝矢状分割術 術式と正確度検証

    今井 治樹, 大村 進, 藤田 紘一, 山下 陽介, 高須 曜, 竹田 敦, 矢島 康治, 本田 康二, 岩井 俊憲, 小野 卓史, 廣田 誠, 光藤 健司

    日本顎変形症学会雑誌   29 ( 2 )   221 - 221   2019.5

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  • オステオトミーガイド、プレベンドプレートを用いた頭蓋基準の上顎位置決め法の正確度

    今井 治樹, 大村 進, 藤田 紘一, 山下 陽介, 高須 曜, 竹田 敦, 矢島 康治, 本田 康二, 岩井 俊憲, 小野 卓史, 廣田 誠, 光藤 健司

    日本顎変形症学会雑誌   29 ( 2 )   222 - 222   2019.5

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  • 流体解析を用いた口腔癌に対する動注化学療法における血管壁面への力学的影響の検証

    北島 大朗, 岩井 俊憲, 矢島 康治, 小栗 千里, 小泉 敏之, 來生 知, 光藤 健司, 藤内 祝

    頭頸部癌   43 ( 2 )   219 - 219   2017.5

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  • 梨状孔下縁切削を併用した上下顎移動術前後における鼻呼吸機能の流体解析

    喜田 壮馬, 島崎 一夫, 矢島 康治, 岩井 俊憲, 大村 進, 小野 卓史

    日本顎変形症学会雑誌   26 ( 2 )   121 - 121   2016.5

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  • 口腔癌に対する逆行性動注化学療法における流体解析を用いた抗癌剤分配シミュレーション

    北島 大朗, 岩井 俊憲, 大原 良仁, 矢島 康治, 小泉 敏之, 光藤 健司, 大島 まり, 藤内 祝

    頭頸部癌   41 ( 2 )   192 - 192   2015.5

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  • 上下顎移動術前後における鼻呼吸機能の流体解析

    喜田 壮馬, 島崎 一夫, 矢島 康治, 大島 まり, 大村 進, 小野 卓史

    日本矯正歯科学会大会プログラム・抄録集   73回   258 - 258   2014.10

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  • Hunter舌炎に対するビタミンB12内服療法の臨床的検討

    石橋 真乃介, 黒木 祐吾, 矢島 康治, 岡本 喜之, 川田 賢介, 石川 好美

    歯科薬物療法   33 ( 2 )   95 - 95   2014.5

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  • 流体解析を用いた動注化学療法の抗癌剤分配シミュレーション

    北島 大朗, 岩井 俊憲, 大原 良仁, 矢島 康治, 光藤 健司, 藤内 祝

    頭頸部癌   40 ( 2 )   218 - 218   2014.5

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  • 2G11 Influences of narrow upper airway on inspiration in pharyngeal space

    YAJIMA Yasuharu, IWAI Toshinori, KITA Soma, KITAJIMA Hiroaki, OHARA Yoshihito, OMURA Susumu, ONO Takashi, OSHIMA Marie, TOHNAI Iwai

    The Proceedings of the Bioengineering Conference Annual Meeting of BED/JSME   2014 ( 0 )   521 - 522   2014

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    Language:Japanese   Publisher:The Japan Society of Mechanical Engineers  

    DOI: 10.1299/jsmebio.2014.26.521

    CiNii Books

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  • 1G16 The Anti-cancer Drug Flow Simulation of the External Carotid Artery using Computational Fluid Dynamics

    KITAJIMA Hiroaki, OSHIMA Marie, IWAI Toshinori, OHHARA Yoshihito, YAJIMA Yasuharu, MITSUDO Kenji, TOHNAI Iwai

    The Proceedings of the Bioengineering Conference Annual Meeting of BED/JSME   2014 ( 0 )   217 - 218   2014

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    DOI: 10.1299/jsmebio.2014.26.217

    CiNii Books

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  • 下顎枝矢状分割術による下顎後方移動に伴う上気道変化の流体力学的解析

    矢島 康治, 岩井 俊憲, 本田 康二, 君塚 幸子, 村田 彰吾, 藤田 紘一, 渋谷 直樹, 島崎 一夫, 大村 進, 藤内 祝

    日本顎変形症学会雑誌   23 ( 2 )   155 - 155   2013.5

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  • 外頸動脈における血流動態の基礎的研究 流体解析を用いた血流シミュレーション

    大原 良仁, 岩井 俊憲, 矢島 康治, 大屋 貴志, 光藤 健司, 藤内 祝

    日本口腔外科学会雑誌   57 ( Suppl. )   189 - 189   2011.9

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  • 手術支援ナビゲーションガイド下に施行した顎関節強直症手術

    君塚 幸子, 矢島 康治, 山下 陽介, 小澤 知倫, 青木 伸二郎, 大村 進, 藤内 祝

    日本口腔外科学会雑誌   55 ( Suppl. )   113 - 113   2009.9

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  • 顔面多発外傷後の中顔面の変形に対する上顎骨延長の有用性

    矢島 康治, 山下 陽介, 青木 伸二郎, 君塚 幸子, 小澤 智倫, 大村 進, 藤内 祝

    日本口腔外科学会雑誌   55 ( Suppl. )   101 - 101   2009.9

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  • 馬蹄形変法により全歯槽部骨切り術を施行したGummy smileを伴う骨格性下顎前突患者の1例

    長谷川 幸生, 福山 英治, 山下 陽介, 矢島 康治, 君塚 幸子, 島崎 一夫, 米満 郁男, 小澤 知倫, 青木 伸二郎, 大村 進, 藤内 祝

    日本顎変形症学会雑誌   19 ( 2 )   79 - 79   2009.5

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  • 上下顎に骨延長を施行したHemifacial Microsomia Type IIbの1例

    山下 陽介, 尾崎 周作, 島崎 一夫, 米満 郁男, 矢島 康治, 君塚 幸子, 小澤 知倫, 青木 伸二郎, 大村 進, 藤内 祝

    日本顎変形症学会雑誌   19 ( 2 )   75 - 75   2009.5

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  • 骨格性下顎前突患者のCheek lineの特徴と上下顎移動術後の変化 3次元再構築画像による評価

    君塚 幸子, 福山 英治, 島崎 一夫, 米満 郁男, 山下 陽介, 矢島 康治, 小澤 知倫, 青木 伸二郎, 大村 進, 藤内 祝

    日本顎変形症学会雑誌   19 ( 2 )   84 - 84   2009.5

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Presentations

  • Long-term outcomes of the surgery to treat obstructive sleep apnea Invited

    Yasuharu Yajima

    The Japanese Academy of Dental Sleep Medicine  2019.11 

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    Event date: 2019.11

    Language:Japanese   Presentation type:Public lecture, seminar, tutorial, course, or other speech  

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  • Application and possibility of upper airway analyzing from the basic principle of CFD Invited

    Yasuharu Yajima

    The 44th Annual Meeting of Japanese Society of Sleep Research, Symposium 3  2019.6 

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    Event date: 2019.6

    Language:Japanese   Presentation type:Symposium, workshop panel (nominated)  

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  • Breathing airflow from the perspective of physics Invited

    Yasuharu Yajima

    The 44th Annual Meeting of Japanese Society of Sleep Research  2018.7 

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    Event date: 2018.7

    Language:Japanese   Presentation type:Public lecture, seminar, tutorial, course, or other speech  

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  • Bartter症候群を伴う下顎前突症患者の下顎形成手術における周術期管理の経験

    大澤 昂平, 岡本 喜之, 柳田 健, 杉浦 圭, 矢島 康治, 光藤 健司

    日本口腔科学会雑誌  2021.9  (NPO)日本口腔科学会

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    Event date: 2021.9

    Language:Japanese  

    Bartter症候群は低カリウム血症を特徴とするまれな疾患である。われわれはBartter症候群患者の周術期管理を経験したので報告する。不正咬合を主訴にBartter症候群の18歳の女性が当院を受診した。下顎前突症のため術前矯正後、全身麻酔下で下顎形成術を施行した。周術期に低カリウム血症を発症する可能性があったため、担当医師に相談し、手術開始時からカリウム投与を開始した。その結果、周術期に低カリウム血症を発症せず、全身状態は良好であった。(著者抄録)

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    Other Link: https://search-tp.jamas.or.jp/index.php?module=Default&action=Link&pub_year=2021&ichushi_jid=J01072&link_issn=&doc_id=20211013250011&doc_link_id=10.11277%2Fstomatology.70.267&url=https%3A%2F%2Fdoi.org%2F10.11277%2Fstomatology.70.267&type=J-STAGE&icon=https%3A%2F%2Fjk04.jamas.or.jp%2Ficon%2F00007_2.gif

  • 窒素含有ビスホスホネート製剤が骨芽細胞の接着と骨組織形成に与える影響に関する研究

    小山 千佳, 廣田 誠, 岡本 喜之, 矢島 康治, 岩井 俊憲, 光藤 健司

    日本口腔科学会雑誌  2021.7  (NPO)日本口腔科学会

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  • 舌扁平上皮癌に対する逆行性超選択的動注化学放射線療法に関する検討

    大屋 貴志, 陳 雪霏, 石川 聡一郎, 林 雄一郎, 大橋 伸英, 矢島 康治, 馬場 隼一, 岩井 俊憲, 小栗 千里, 小泉 敏之, 來生 知, 光藤 健司

    頭頸部癌  2021.5  (一社)日本頭頸部癌学会

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  • ナビゲーションシステムと二分割サージカルガイドを用いて骨削除術を行った下顎骨線維性異形成症の1例

    矢島 康治, 岩井 俊憲, 本田 康二, 光藤 健司

    日本顎変形症学会雑誌  2021.5  (NPO)日本顎変形症学会

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  • Deep Learningを用いた口腔衛生評価のための画像選別

    野田 明里, 村上 遥, 大屋 貴志, 矢島 康治, 光藤 健司, 星 和人

    日本口腔ケア学会雑誌  2021.4  (一社)日本口腔ケア学会

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  • 口腔癌検知に向けた自動化処理によるDataSet作成

    野田 明里, 村上 遥, 大屋 貴志, 矢島 康治, 光藤 健司, 星 和人

    日本口腔ケア学会雑誌  2021.4  (一社)日本口腔ケア学会

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  • Preoperative planning using CT angiography and computer assisted mandibular reconstruction with the fibula

    Fujino M, Iwai T, Matsui Y, Maegawa J, Yajima Y, Ohya T, Ohhara Y, Hirota M, Mitsudo K, Tohnai I

    9th Asian Congress on Oral and Maxillofacial Surgery, Kuala Lumpur, Malaysia  2010.11 

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  • Intraoperative 3D imaging for endoscopically-assisted reduction and fixation of subcondylar fractures

    Okubo M, Iwai T, Matsui Y, Maegawa J, Yajima Y, Ohya T, Ohhara Y, Hirota M, Mitsudo K, Tohnai I

    9th Asian Congress on Oral and Maxillofacial Surgery, Kuala Lumpur, Malaysia  2010.11 

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  • Endoscopically-assisted intraoral removal of lipoma in the buccal space

    Koyama C, Iwai T, Matsui Y, Maegawa J, Yajima Y, Ohya T, Ohhara Y, Hirota M, Mitsudo K, Tohnai I

    9th Asian Congress on Oral and Maxillofacial Surgery, Kuala Lumpur, Malaysia  2010.11 

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  • Endoscopically-assisted submandibular sialoadenectomy

    Iwai T, Matsui Y, Yajima Y, Ohya T, Ohhara Y, Chikumaru H, Hirota M, Mitsudo K, Tohnai I

    Congress of the European Association for Cranio-Maxillofacial Surgery, Bruges, Belgium  2010.9 

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  • Oral stings by spermatophores of squid

    Iwai T, Yajima Y, Ohya T, Ohhara Y, Mitsunaga S, Hirota M, Mitsudo K, Tohnai I

    Congress of the European Association for Cranio-Maxillofacial Surgery, Bruges, Belgium  2010.9 

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  • Image guided correction of mandibular asymmetry in patient with Garre's osteomyelitis under endoscopic and navigation guidance

    Iwai T, Yajima Y, Ohya T, Ohhara Y, Chikumaru H, Hirota M, Mitsudo K, Tohnai I

    Congress of the European Association for Cranio-Maxillofacial Surgery, Bruges, Belgium  2010.9 

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Awards

  • Poster Award

    2019.10   The Japanese Society of Oral and Maxillofacial Surgeons   Evaluation of acoustic power level in the pharyngeal airway before and after mandibular setback surgery using computational fluid dynamics study

    Yasuharu Yajima

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  • Poster Award

    2018.11   The Japanese Society of Oral and Maxillofacial Surgeons   Computational fluid dynamics study of the pharyngeal airway in mandibular setback surgery for mandibular prognathism

    Yasuharu Yajima

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  • Poster Award

    2013.6   The Japanese Society for Jaw Deformities  

    Yasuharu Yajima

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Other

  • がん治療認定医

    2022.4

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    一般社団法人 日本がん治療認定医機構

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  • 日本口腔外科学会 専門医

    2020.4

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    公益社団法人 日本口腔外科学会

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  • 日本歯科薬物療法学会 専門医

    2017.7

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    一般社団法人日本歯科薬物療法学会

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Teaching Experience

  • 臨床実習(口腔外科学)

    2020.1 Institution:横浜市立大学

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