Updated on 2025/06/21

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写真a

 
Kozo Okada
 
Organization
YCU Medical Center Associate Professor
Title
Associate Professor
Homepage
https://www.yokohama-cu.ac.jp/urahp/section/heart/index.html
Profile

最新の診断・治療デバイスを用いた冠動脈疾患、動脈硬化、生活習慣病、非閉塞性冠動脈疾患、心不全などの研究を行なっています。その他にも、メディカルデバイスの開発や人工知能と医療を融合した創造医療の研究、遠隔・在宅診療や他領域など分野を超えた共同研究、臨床から生まれる疑問を解決するためのトランスレーショナルリサーチなど幅広い研究活動を精力的に行っています。

【学歴】
2003年  3月　横浜市立大学 医学部 医学科 卒業
2014年  7月　横浜市立大学 博士（医学博士）

【職歴】
2003年  4月　横浜市立大学附属病院　初期研修医
2004年  4月　横浜市立大学附属市民総合医療センター　初期研修医
2005年  4月   国際医療福祉大学附属熱海病院　循環器内科
2007年  4月　済生会横浜市南部病院　循環器内科
2010年  4月   横浜市立大学附属市民総合医療センター　心臓血管センター　指導診療医
2013年  6月   米国スタンフォード大学　Postdoctoral research fellow
2017年10月　横浜市立大学附属市民総合医療センター　心臓血管センター内科　指導診療医
2018年  4月   横浜市立大学附属市民総合医療センター　心臓血管センター内科　助教
2021年  4月　横浜市立大学附属市民総合医療センター　心臓血管センター内科　講師（専任）
　　　　　　 横浜市立大学附属市民総合医療センター　次世代臨床研究センター　講師（兼任）
　　　　　　 神奈川歯科大学　特任講師（兼任）
2024年 4月　横浜市立大学附属市民総合医療センター　心臓血管センター内科　准教授（専任）
　　　　　　 横浜市立大学附属市民総合医療センター　次世代臨床研究センター　准教授（兼任）
　　　　　　 神奈川歯科大学　特任准教授（兼任）

【認定資格】
日本内科学会認定　内科認定医
日本循環器学会認定　循環器専門医
日本心臓病学会　心臓病上級臨床医（FJCC）
日本心血管インターベンション治療学会認定　インターベンション認定医
日本医師会認定　産業医
日本心不全学会主催　第26回基本的心不全緩和ケアトレーニングコース（HEPT）修了
難病指定医

【受賞歴】
2013年　16th Stanford Cardiovascular Research Scholarship Program
2014年　Stanford University, Cardiovascular Institute Travel Award
2015年　Stanford University, Cardiovascular Institute Travel Award
2015年　The 27th Transcatheter Cardiovascular Therapeutics Top 50 Abstract Award
2016年　The 28th Transcatheter Cardiovascular Therapeutics Top 50 Poster Award
2016年　Stanford University, Cardiovascular Institute Manuscript Award
2017年　Strategy and Treatment For Cardiovascular Disease Award最優演題
2019年　第29回日本心血管画像動態学会 Young Investigator Award最優秀賞
2021年　第259回日本循環器学会関東甲信越地方会 Clinical Research Award 2021最優秀賞
2023年　公立大学法人横浜市立大学　令和4年理事長・学長表彰　教員部門「奨励賞」
2024年　日本心血管画像動態学会 心血管画像診断学賞：Cardiovascular Imaging Award（吉川純一賞）
2025年　令和6年度　公立大学法人横浜市立大学附属市民総合医療センター　病院長表彰

【産業財産権】
特許第7246664号（情報処理装置、情報処理方法、情報処理システム、及び情報処理プログラム）
特許第7672033号（心不全推定装置、心不全推定システム、心不全 推定方法、及び心不全推定プログラム）

【委員歴】
日本循環器学会関東甲信越支部 学術委員会委員（2021年4月〜2025年3月）
日本循環器学会関東甲信越支部 評議委員会評議員（2022年12月〜現在）
一般社団法人日本心臓病学会 代議員（2024年10月〜現在）

【所属学会】
日本内科学会、日本循環器学会、日本心血管インターベンション治療学会、日本心臓病学会（FJCC）、日本心エコー図学会、日本心不全学会、日本老年医学会、日本冠疾患学会、日本高血圧学会、日本心臓リハビリテーション学会、日本バイオデザイン学会、日本画像動態学会、アメリカ循環器協会（AHA）、アメリカ心臓病学会（ACC）、欧州心臓病協会（ESC）

【競争的資金】
日本学術振興会 科研費 基盤C：糖尿病合併冠動脈疾患患者に対する強化多因子治療の冠動脈プラーク退縮効果（代表）
国土交通省 令和5年度交通運輸技術開発推進制度：AIによるドライバーの心不全を予見する研究（代表）
AMED 令和６年度 医療機器等研究成果展開事業 チャレンジタイプ：心不全予測を行う表情・音声の新規バイオマーカーに関する開発研究（代表）
他多数あり

【特定臨床研究、医師主導治験など】
糖尿病合併冠動脈疾患患者に対する強化多因子治療の冠動脈プラーク退縮効果（特定臨床研究）

 

External link

Degree

  • 博士（医学）

Research Interests

  • 産学連携、医工連携

  • Coronary Intervention

  • Remote Patient Management

  • M-D Consotium

  • 老年医療

  • Life Style Modification

  • Myocardial Infarction

  • Digital Biomarker

  • Personal Health Record

  • Heart Failure

  • Artificial Intelligence

  • Intravascular Imaging

Research Areas

  • Life Science / Cardiology  / Coronary risk factors

  • Life Science / Cardiology  / Non-onstractive myocardial ischemia

  • Life Science / Cardiology  / Heart Failure

  • Life Science / Cardiology  / Artificial intelligent

  • Life Science / Cardiology  / Intravascular imaging

  • Life Science / Cardiology  / Intervention

  • Life Science / Cardiology  / Coronary Artery Disease

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Education

  • Yokohama City University   Graduate School of Medicine   Doctor of Medical Science

    - 2013

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  • Yokohama City University   School of Medicine   Doctor of Medicine

    1997 - 2003

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Research History

  • 横浜市立大学附属市民総合医療センター, 心臓血管センター内科, 准教授（専任）

    2024.4

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  • 横浜市立大学附属市民総合医療センター 次世代臨床研究センター, 准教授（兼任）

    2024.4

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  • 神奈川歯科大学, 特任准教授（兼任）

    2024.4

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  • 横浜市立大学大学院医学研究科 YCU病院経営プログラム

    2023.4 - 2024.3

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  • 日本心不全学会主催   第26回基本的心不全緩和ケアトレーニングコース（HEPT）修了

    2022.3

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  • Kanagawa Dental College

    2021.4 - 2024.3

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  • Yokohama City University Medical Center   Cardiovascular Center   Lecturer

    2021.4 - 2024.3

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  • 横浜市立大学附属市民総合医療センター 次世代臨床研究センター   講師（兼任）

    2021.4 - 2024.3

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  • Yokohama City University Medical Center   Cardiovascular Center   Assistant Professor

    2018.4 - 2021.3

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  • Yokohama City University Medical Center   Cardiovascular Center   Staff Cardiologist

    2017.10 - 2018.3

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  • Stanford University School of Medicine   Division of Cardiovascular Medicine   Postdoctoral Fellow

    2013.6 - 2017.8

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  • Yokohama City University Medical Center   Cardiovascular Center   Staff Cardiologist

    2010.4 - 2013.5

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  • Saiseikai Yokohama City Nanbu Hospital

    2007.4 - 2010.3

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  • University of Health and Welfare Atami Hospital

    2005.4 - 2007.3

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  • Yokohama City University Medical Center   Junior Resident

    2004.4 - 2005.3

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  • Yokohama City University   Junior Resident

    2003.4 - 2004.3

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Professional Memberships

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Committee Memberships

  • 一般社団法人日本心臓病学会   代議員  

    2024.10   

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    Committee type：Academic society

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  • 日本循環器学会関東甲信越支部評議委員会   評議委員  

    2022.12   

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    Committee type：Academic society

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  • 日本循環器学会関東甲信越支部   学術委員会委員  

    2021.4 - 2025.3   

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    Committee type：Academic society

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Papers

  • Effect of Intensified Multifactorial Treatments on Coronary Atherosclerosis in Patients With Coronary Artery Disease and Type 2 Diabetes Mellitus ― Rationale and Design of the Randomized IMPACT-DM Trial ― Reviewed

    Kozo Okada, Shinnosuke Kikuchi, Nobuhiko Maejima, Noriyuki Kawaura, Sho Kodama, Naoki Nakayama, Kenichiro Saka, Shunsuke Kataoka, Hiroyuki Suzuki, Hiroyuki Ishikawa, Shotaro Kuji, Yuki Saigusa, Chika Kawashima, Hidekuni Kirigaya, Yohei Hanajima, Hidefumi Nakahashi, Masaomi Gohbara, Jun Okuda, Kengo Tsukahara, Kazuki Fukui, Tsutomu Endo, Teruyasu Sugano, Kiyoshi Hibi

    Circulation Reports   7 ( 6 )   486 - 490   2025.6

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    Authorship：Lead author,　Corresponding author   Publishing type：Research paper (scientific journal)   Publisher：Japanese Circulation Society  

    DOI： 10.1253/circrep.cr-25-0021

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  • Cutting balloon versus standard balloon for lesion preparation of drug-coated balloon treatment in de-novo coronary artery lesions: Rationale and Design of the Randomized NATURE trial Reviewed

    Masafumi Ono, Taku Asano, Masahiko Noguchi, Norihiro Kogame, Raisuke Iijima, Kohei Osakada, Kenji Ando, Takayuki Ishihara, Koji Nishida, Mamoru Nanasato, Kengo Tanabe, Takashi Muramatsu, Atsunori Okamura, Yoshihisa Kinoshita, Kiyoshi Hibi, Satoru Suwa, Nehiro Kuriyama, Kozo Okada, Gaku Nakazawa, Takashi Ashikaga, Yutaka Tadano, Hiroki Shiomi, Masato Nakamura, Akiyoshi Miyazawa, Satoshi Miyata, Kiyoko Uno, Kazushige Kadota, Ken Kozuma

    Cardiovascular Revascularization Medicine   2025.3

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    Publishing type：Research paper (scientific journal)   Publisher：Elsevier BV  

    DOI： 10.1016/j.carrev.2025.03.009

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  • Early, Intensive and Persistent Lipid-Lowering Therapy for Secondary Prevention of Acute Coronary Syndrome Reviewed

    Kozo Okada, Tatsuya Haze, Shinnosuke Kikuchi, Hidekuni Kirigaya, Yohei Hanajima, Katsuhiko Tsutsumi, Jin Kirigaya, Hidefumi Nakahashi, Masaomi Gohbara, Yuichiro Kimura, Masami Kosuge, Toshiaki Ebina, Teruyasu Sugano, Kiyoshi Hibi

    Journal of Atherosclerosis and Thrombosis   31 ( 12 )   1748 - 1762   2024.12

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    Authorship：Lead author   Publishing type：Research paper (scientific journal)   Publisher：Japan Atherosclerosis Society  

    DOI： 10.5551/jat.64988

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  • Long-term outcomes and operators’ experience in primary percutaneous coronary intervention for ST-segment elevation myocardial infarction Reviewed

    Kei Takamizawa, Masaomi Gohbara, Yohei Hanajima, Katsuhiko Tsutsumi, Hidekuni Kirigaya, Jin Kirigaya, Hidefumi Nakahashi, Yugo Minamimoto, Yuichiro Kimura, Noriyuki Kawaura, Kensuke Matsushita, Kozo Okada, Masaaki Konishi, Noriaki Iwahashi, Masami Kosuge, Teruyasu Sugano, Toshiaki Ebina, Kiyoshi Hibi

    Cardiovascular Intervention and Therapeutics   40 ( 1 )   57 - 67   2024.10

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    Publishing type：Research paper (scientific journal)   Publisher：Springer Science and Business Media LLC  

    DOI： 10.1007/s12928-024-01059-5

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    Other Link： https://link.springer.com/article/10.1007/s12928-024-01059-5/fulltext.html

  • High Detectability of Prehospital 12-Lead Electrocardiogram in Diagnosing Spasm-Induced Acute Coronary Syndrome. Reviewed

    Jin Kirigaya, Yasushi Matsuzawa, Masami Kosuge, Takeru Abe, Noriaki Iwahashi, Kengo Terasaka, Hisaya Kondo, Kensuke Matsushita, Masaomi Gohbara, Kozo Okada, Masaaki Konishi, Toshiaki Ebina, Teruyasu Sugano, Kiyoshi Hibi

    Circulation Journal   88 ( 11 )   1800 - 1808   2024.9

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    Language：English   Publishing type：Research paper (scientific journal)  

    BACKGROUND: The importance of prehospital (PH) electrocardiograms (ECG) recorded by emergency medical services (EMS) for diagnosing coronary artery spasm-induced acute coronary syndrome (CS-ACS) remains unclear. METHODS AND RESULTS: We enrolled 340 consecutive patients with ACS who were transported by EMS within 12 h of symptom onset. According to Japanese Circulation Society guidelines, CS-ACS (n=48) was diagnosed with or without a pharmacological provocation test (n=34 and n=14, respectively). Obstructive coronary artery-induced ACS (OC-ACS; n=292) was defined as ACS with a culprit lesion showing 99% stenosis or >75% stenosis with plaque rupture or thrombosis observed via angiographic and intravascular imaging. Ischemic ECG findings included ST-segment deviation (elevation or depression) and negative T and U waves. In CS-ACS, the prevalence of ST-segment deviation decreased significantly from PH-ECG to emergency room (ER) ECG (77.0% vs. 35.4%; P<0.001), as did the prevalence of overall ECG abnormalities (81.2% vs. 45.8%; P<0.001). Conversely, in OC-ACS, there was a similar prevalence on PH-ECG and ER-ECG of ST-segment deviations (94.8% vs. 92.8%, respectively; P=0.057) and abnormal ECG findings (96.9% vs. 95.2%, respectively; P=0.058). Patients with abnormal PH-ECG findings that disappeared upon arrival at hospital without ER-ECG or troponin abnormalities were more frequent in the CS-ACS than OC-ACS group (20.8% vs. 1.0%; P<0.001). CONCLUSIONS: PH-ECG is valuable for detecting abnormal ECG findings that disappear upon arrival at hospital in CS-ACS patients.

    DOI： 10.1253/circj.CJ-24-0485

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  • Using a Quality Management System and Risk-based Approach in Observational Studies to Obtain Robust Real-World Evidence Reviewed

    Reo Tanoshima, Naoko Inagaki, Manabu Nitta, Soichiro Sue, Sayuri Shimizu, Tatsuya Haze, Kotaro Senuki, Chihiro Sano, Hajime Takase, Makoto Kaneko, Akito Nozaki, Kozo Okada, Kohei Ohyama, Atsushi Kawaguchi, Yusuke Kobayashi, Hideki Oi, Shin Maeda, Yuichiro Yano, Yuji Kumagai, Etsuko Miyagi

    Therapeutic Innovation &amp; Regulatory Science   58 ( 6 )   1006 - 1013   2024.9

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    Publishing type：Research paper (scientific journal)   Publisher：Springer Science and Business Media LLC  

    DOI： 10.1007/s43441-024-00695-6

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    Other Link： https://link.springer.com/article/10.1007/s43441-024-00695-6/fulltext.html

  • Elevated Leukocyte Count and Platelet-Derived Thrombogenicity Measured Using the Total Thrombus-Formation Analysis System in Patients with ST-Segment Elevation Myocardial Infarction Reviewed

    Shinnosuke Kikuchi, Kengo Tsukahara, Shinya Ichikawa, Takeru Abe, Hidefumi Nakahashi, Yugo Minamimoto, Yuichiro Kimura, Eiichi Akiyama, Kozo Okada, Yasushi Matsuzawa, Masaaki Konishi, Nobuhiko Maejima, Noriaki Iwahashi, Masami Kosuge, Toshiaki Ebina, Kouichi Tamura, Kazuo Kimura, Kiyoshi Hibi

    Journal of Atherosclerosis and Thrombosis   31 ( 9 )   1277 - 1292   2024.9

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    Publishing type：Research paper (scientific journal)   Publisher：Japan Atherosclerosis Society  

    DOI： 10.5551/jat.64395

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  • Serum mature and furin-cleaved proprotein convertase subtilisin/kexin type 9 levels and their association with cardiovascular events in statin-treated patients with cardiovascular disease Reviewed

    Kiyoshi Hibi, Masaomi Gohbara, Kohei Uemura, Noriaki Iwahashi, Kozo Okada, Hiroshi Iwata, Yoshihiro Fukumoto, Takafumi Hiro, Yukio Ozaki, Satoshi Iimuro, Ichiro Sakuma, Seiji Hokimoto, Katsumi Miyauchi, Yutaka Matsuyama, Yoshihisa Nakagawa, Hisao Ogawa, Hiroyuki Daida, Hiroaki Shimokawa, Yasushi Saito, Takeshi Kimura, Masunori Matsuzaki, Kazuo Kimura, Ryozo Nagai

    Journal of Clinical Lipidology   18 ( 5 )   e844 - e854   2024.9

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    Publishing type：Research paper (scientific journal)   Publisher：Elsevier BV  

    DOI： 10.1016/j.jacl.2024.07.002

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  • Clinical Utility of Machine Learning-Derived Vocal Biomarkers in the Management of Heart Failure Reviewed

    Kozo Okada, Daisuke Mizuguchi, Yasuhiro Omiya, Koji Endo, Yusuke Kobayashi, Noriaki Iwahashi, Masami Kosuge, Toshiaki Ebina, Kouichi Tamura, Teruyasu Sugano, Tomoaki Ishigami, Kazuo Kimura, Kiyoshi Hibi

    Circulation Reports   6 ( 8 )   303 - 312   2024.8

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    Authorship：Lead author,　Corresponding author   Publishing type：Research paper (scientific journal)   Publisher：Japanese Circulation Society  

    DOI： 10.1253/circrep.cr-24-0064

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  • Role of Sex Difference in Modifiable Risk Factors After Acute Myocardial Infarction Invited Reviewed

    Kozo Okada

    Circulation Journal   88 ( 8 )   1223 - 1224   2024.7

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    Authorship：Lead author,　Last author,　Corresponding author   Publishing type：Research paper (scientific journal)   Publisher：Japanese Circulation Society  

    DOI： 10.1253/circj.cj-24-0289

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  • Impact of New-Onset Right Bundle-Branch Block After Transcatheter Aortic Valve Replacement on Permanent Pacemaker Implantation. Reviewed International journal

    Shinnosuke Kikuchi, Yugo Minamimoto, Kensuke Matsushita, Tomoki Cho, Kengo Terasaka, Yohei Hanajima, Hidefumi Nakahashi, Masaomi Gohbara, Yuichiro Kimura, Shota Yasuda, Kozo Okada, Yasushi Matsuzawa, Noriaki Iwahashi, Masami Kosuge, Toshiaki Ebina, Olivier Morel, Patrick Ohlmann, Keiji Uchida, Kiyoshi Hibi

    Journal of the American Heart Association   13 ( 9 )   e032777   2024.5

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    Language：English   Publishing type：Research paper (scientific journal)  

    BACKGROUND: A delayed and recurrent complete atrioventricular block (CAVB) is a life-threatening complication of transcatheter aortic valve replacement (TAVR). Post-TAVR evaluation may be important in predicting delayed and recurrent CAVB requiring permanent pacemaker implantation (PPI). The impact of new-onset right bundle-branch block (RBBB) after TAVR on PPI remains unknown. METHODS AND RESULTS: In total, 407 patients with aortic stenosis who underwent TAVR were included in this analysis. Intraprocedural CAVB was defined as CAVB that occurred during TAVR. A 12-lead ECG was evaluated at baseline, immediately after TAVR, on postoperative days 1 and 5, and according to the need to identify new-onset bundle-branch block (BBB) and CAVB after TAVR. Forty patients (9.8%) required PPI, 17 patients (4.2%) had persistent intraprocedural CAVB, and 23 (5.7%) had delayed or recurrent CAVB after TAVR. The rates of no new-onset BBB, new-onset left BBB, and new-onset RBBB were 65.1%, 26.8%, and 4.7%, respectively. Compared with patients without new-onset BBB and those with new-onset left BBB, the rate of PPI was higher in patients with new-onset RBBB (3.4% versus 5.6% versus 44.4%, P<0.0001). On post-TAVR evaluation in patients without persistent intraprocedural CAVB, the multivariate logistic regression analysis showed that new-onset RBBB was a statistically significant predictor of PPI compared with no new-onset BBB (odds ratio [OR], 18.0 [95% CI, 5.94-54.4]) in addition to the use of a self-expanding valve (OR, 2.97 [95% CI, 1.09-8.10]). CONCLUSIONS: Patients with new-onset RBBB after TAVR are at high risk for PPI.

    DOI： 10.1161/JAHA.123.032777

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  • Impact of Low-Density Lipoprotein Cholesterol Levels at Acute Coronary Syndrome Admission on Long-Term Clinical Outcomes Reviewed

    Ryosuke Sato, Yasushi Matsuzawa, Tomohiro Yoshii, Eiichi Akiyama, Masaaki Konishi, Hidefumi Nakahashi, Yugo Minamimoto, Yuichiro Kimura, Kozo Okada, Nobuhiko Maejima, Noriaki Iwahashi, Masami Kosuge, Toshiaki Ebina, Kazuo Kimura, Kouichi Tamura, Kiyoshi Hibi

    Journal of Atherosclerosis and Thrombosis   31 ( 4 )   444 - 460   2024.4

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    Publishing type：Research paper (scientific journal)   Publisher：Japan Atherosclerosis Society  

    DOI： 10.5551/jat.64368

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  • Association between evolocumab use and slow progression of aortic valve stenosis Reviewed

    Kengo Terasaka, Masaomi Gohbara, Takeru Abe, Tomohiro Yoshii, Yohei Hanajima, Jin Kirigaya, Mutsuo Horii, Shinnosuke Kikuchi, Hidefumi Nakahashi, Kensuke Matsushita, Yugo Minamimoto, Kozo Okada, Yasushi Matsuzawa, Noriaki Iwahashi, Masami Kosuge, Teruyasu Sugano, Toshiaki Ebina, Kiyoshi Hibi

    Heart and Vessels   39 ( 8 )   725 - 734   2024.3

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    Publishing type：Research paper (scientific journal)   Publisher：Springer Science and Business Media LLC  

    DOI： 10.1007/s00380-024-02386-6

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    Other Link： https://link.springer.com/article/10.1007/s00380-024-02386-6/fulltext.html

  • Influence of Obstructive Apnea Index on Persistent Left Ventricular Dysfunction in Patients with ST-Segment Elevation Myocardial Infarction Reviewed

    Jin Kirigaya, Noriaki Iwahashi, Tomoaki Ishigami, Takeru Abe, Masaomi Gohbara, Yohei Hanajima, Mutsuo Horii, Kozo Okada, Yasushi Matsuzawa, Masami Kosuge, Toshiaki Ebina, Kiyoshi Hibi

    Journal of Clinical Medicine   13 ( 4 )   986 - 986   2024.2

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    Publishing type：Research paper (scientific journal)   Publisher：MDPI AG  

    Background: We retrospectively investigated the effects of the severity and classification of sleep-disordered breathing (SDB) on left ventricular (LV) function in patients with ST-segment elevation myocardial infarction (STEMI). Methods: A total of 115 patients with STEMIs underwent a sleep study using a multichannel frontopolar electroencephalography recording device (Sleep Profiler) one week after STEMI onset. We evaluated LV global longitudinal strain (LV-GLS) using two-dimensional echocardiography at one week and seven months. Patients were classified as no SDB (AHI &lt; 5 events/h), obstructive SDB (over 50% of apnea events are obstructive), and central SDB (over 50% of apnea events are central). Due to the device’s limitations in distinguishing obstructive from central hypopnea, SDB classification was based on apnea index percentages. Results: The obstructive apnea index (OAI) was significantly associated with LV-GLS at one week (r = 0.24, p = 0.027) and seven months (r = 0.21, p = 0.020). No such correlations were found for the central apnea index and SDB classification. Multivariable regression analysis showed that the OAI was independently associated with LV-GLS at one week (β = 0.24, p = 0.002) and seven months (β = 0.20, p = 0.008). Conclusions: OAI is associated with persistent LV dysfunction assessed by LV-GLS in STEMI.

    DOI： 10.3390/jcm13040986

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  • Ratio of left ventricular outflow tract area to aortic annulus area and complete atrioventricular block after transcatheter aortic valve replacement for aortic stenosis Reviewed

    Shinnosuke Kikuchi, Yugo Minamimoto, Kensuke Matsushita, Tomoki Cho, Kengo Terasaka, Yohei Hanajima, Hidefumi Nakahashi, Masaomi Gohbara, Yuichiro Kimura, Shota Yasuda, Kozo Okada, Yasushi Matsuzawa, Noriaki Iwahashi, Masami Kosuge, Toshiaki Ebina, Olivier Morel, Patrick Ohlmann, Keiji Uchida, Kiyoshi Hibi

    International Journal of Cardiology   397   131608 - 131608   2024.2

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    DOI： 10.1016/j.ijcard.2023.131608

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  • Coronary protection using a pressure wire during transcatheter aortic valve implantation. Reviewed

    Shinnosuke Kikuchi, Kengo Terasaka, Yugo Minamimoto, Tomoki Cho, Kozo Okada, Yasushi Matsuzawa, Noriaki Iwahashi, Keiji Uchida, Kiyoshi Hibi

    Journal of cardiology cases   29 ( 2 )   73 - 77   2024.2

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    UNLABELLED: Coronary obstruction is a rare but life-threatening complication of transcatheter aortic valve implantation (TAVI). This article describes the case of a patient with severe aortic valve stenosis treated with TAVI, during which preventive coronary wiring using a pressure wire was performed for coronary protection. After the deployment of the transcatheter heart valve (THV), the values of the fractional flow reserve (FFR) and resting full-cycle ratio (RFR) remarkably decreased, although the findings of transesophageal echocardiography and coronary angiography did not suggest coronary obstruction. Intravascular ultrasound revealed severe stenosis in the left main trunk due to the displacement of the calcified native leaflets. The decrease in the FFR and RFR values after THV deployment led to a diagnosis of partial coronary obstruction, and percutaneous coronary intervention was successfully performed. In patients at a high risk for coronary obstruction, coronary protection with a pressure wire is useful for the diagnosis and prevention of coronary flow deterioration during TAVI. Functional assessment using a pressure wire before and after TAVI may contribute to the accurate diagnosis of coronary obstruction. LEARNING OBJECTIVE: Accurate diagnosis of coronary obstruction during transcatheter aortic valve implantation (TAVI) is important for successful management. In patients at a high risk for coronary obstruction, coronary protection with a pressure wire is useful for the diagnosis and prevention of coronary flow deterioration during TAVI. The remarkable decrease in the fractional flow reserve and resting full-cycle ratio values after the deployment of the transcatheter heart valve may suggest coronary obstruction.

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  • Clinical Usefulness of Echocardiographic Measurement of Proximal Aortic Diameter in Early Differentiation Between Type A Acute Aortic Dissection and ST‐Segment–Elevation Myocardial Infarction Reviewed

    Jin Kirigaya, Noriaki Iwahashi, Takeru Abe, Masaomi Gohbara, Yohei Hanajima, Mutsuo Horii, Kozo Okada, Yasushi Matsuzawa, Shota Yasuda, Masami Kosuge, Toshiaki Ebina, Ichiro Takeuchi, Keiji Uchida, Kouichi Tamura, Kiyoshi Hibi

    Journal of the American Heart Association   12 ( 21 )   2023.11

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    Background

    <p lang="en">Contradictions between management modalities of type A acute aortic dissection (TAAAD) and ST‐elevation–myocardial infarction (STEMI) may result in clinical catastrophe. Therefore, we aimed to explore which 2‐dimensional echocardiography (2DE) findings are optimal for differentiating TAAAD from STEMI.

    </p> Methods and Results

    <p lang="en"> This study included 340 patients with STEMI and 340 patients with TAAAD who underwent 2DE in the emergency department between 2012 and 2021. The proximal ascending aorta (PAA) diameter and other echocardiographic parameters were analyzed. PAA diameters were measured at 4 levels in the parasternal view: Valsalva, the sinotubular junction (STJ), the PAA at 1 cm above the STJ, and the PAA at 2 cm above the STJ. Receiver‐operating characteristic curve analysis showed that Valsalva, STJ, PAA at 1 cm above the STJ, and PAA at 2 cm above the STJ were significant predictors of TAAAD (areas under the curve: 0.777, 0.924, 0.965, and 0.975, respectively; P &lt;0.001) with the respective cutoff values of 39.4, 38.5, 39.8, and 41.2 mm. Multivariable analysis suggested that all 2DE parameters were significant predictors of TAAAD. Among the 2DE parameters examined, the incorporation of PAA at 2 cm above the STJ to clinical indicators exhibited the most significant diagnostic capability (C‐statistics, 0.97; net reclassification improvement, 1.81; integrated discrimination improvement, 0.61). When only TAAAD with coronary malperfusion and STEMI were analyzed, the diagnostic utility of PAA at 1 cm above the STJ was evident (C‐statistics, 0.99; net reclassification improvement, 1.79; integrated discrimination improvement, 0.67), with PAA at 2 cm above the STJ ranking second in diagnostic significance (C‐statistics, 0.99; net reclassification improvement, 1.12; integrated discrimination improvement, 0.66).

    </p> Conclusions

    <p lang="en">PAA measurements were the most beneficial for diagnosing TAAAD in all 2DE findings and TAAAD from STEMI.

    </p>

    DOI： 10.1161/jaha.123.029506

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  • Prognostic importance of glycemic variability on left ventricular reverse remodeling after the first episode of ST-segment elevation myocardial infarction. Reviewed International journal

    Yohei Hanajima, Noriaki Iwahashi, Jin Kirigaya, Mutsuo Horii, Yugo Minamimoto, Masaomi Gohbara, Takeru Abe, Kozo Okada, Yasushi Matsuzawa, Masami Kosuge, Toshiaki Ebina, Kiyoshi Hibi

    Cardiovascular Diabetology   22 ( 1 )   202 - 202   2023.8

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    BACKGROUND: This study aimed to investigate the effect of glycemic variability (GV), determined using a continuous glucose monitoring system (CGMS), on left ventricular reverse remodeling (LVRR) after ST-segment elevation myocardial infarction (STEMI). METHODS: A total of 201 consecutive patients with STEMI who underwent reperfusion therapy within 12 h of onset were enrolled. GV was measured using a CGMS and determined as the mean amplitude of glycemic excursion (MAGE). Left ventricular volumetric parameters were measured using cardiac magnetic resonance imaging (CMRI). LVRR was defined as an absolute decrease in the LV end-systolic volume index of > 10% from 1 week to 7 months after admission. Associations were also examined between GV and LVRR and between LVRR and the incidence of major adverse cardiovascular events (MACE; cardiovascular death, acute coronary syndrome recurrence, non-fatal stroke, and heart failure hospitalization). RESULTS: The prevalence of LVRR was 28% (n = 57). The MAGE was independent predictor of LVRR (odds ratio [OR] 0.98, p = 0.002). Twenty patients experienced MACE during the follow-up period (median, 65 months). The incidence of MACE was lower in patients with LVRR than in those without (2% vs. 13%, p = 0.016). CONCLUSION: Low GV, determined using a CGMS, was significantly associated with LVRR, which might lead to a good prognosis. Further studies are needed to validate the importance of GV in LVRR in patients with STEMI.

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  • Biodegradable or durable polymer drug-eluting stents in patients with coronary artery disease: ten-year outcomes of the randomised NEXT Trial Reviewed

    Masahiro Natsuaki, Hirotoshi Watanabe, Takeshi Morimoto, Ken Kozuma, Kazushige Kadota, Toshiya Muramatsu, Yoshihisa Nakagawa, Takashi Akasaka, Keiichi Igarashi Hanaoka, Kengo Tanabe, Yoshihiro Morino, Tetsuya Ishikawa, Harumi Katoh, Hideo Nishikawa, Toshihiro Tamura, Koh Ono, Ko Yamamoto, Takayuki Ishihara, Mitsuru Abe, Ryoji Taniguchi, Yuji Ikari, Kozo Okada, Takeshi Kimura

    EuroIntervention   19 ( 5 )   e402 - e413   2023.8

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    DOI： 10.4244/eij-d-23-00076

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  • Impact of myocardial bridging on coronary artery plaque formation and long-term mortality after heart transplantation Reviewed

    Shigemitsu Tanaka, Kozo Okada, Hideki Kitahara, Helen Luikart, Paul G. Yock, Alan C. Yeung, Ingela Schnittger, Jennifer A. Tremmel, Peter J. Fitzgerald, Kiran K. Khush, William F. Fearon, Yasuhiro Honda

    International Journal of Cardiology   379   24 - 32   2023.5

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    DOI： 10.1016/j.ijcard.2023.03.014

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  • Endothelial dysfunction predicts bleeding and cardiovascular death in acute coronary syndrome. Reviewed International journal

    Tomohiro Yoshii, Yasushi Matsuzawa, So Kato, Ryosuke Sato, Youhei Hanajima, Shinnosuke Kikuchi, Hidefumi Nakahashi, Masaaki Konishi, Eiichi Akiyama, Yugo Minamimoto, Yuichiro Kimura, Kozo Okada, Nobuhiko Maejima, Noriaki Iwahashi, Toshiaki Ebina, Kiyoshi Hibi, Masami Kosuge, Toshihiro Misumi, Kouichi Tamura, Kazuo Kimura

    International Journal of Cardiology   376   11 - 17   2023.4

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    BACKGROUNDS: Recently, there has been increasing awareness that bleeding may lead to adverse outcomes. Endothelial dysfunction is associated with increased risk of cardiovascular and bleeding events. This study aimed to investigate the association of endothelial dysfunction with major bleeding and specific causes of death in addition to major adverse cardiovascular events in patients with acute coronary syndrome. METHODS: This single-centre retrospective observational study was conducted at a tertiary-care hospital; patients with acute coronary syndrome were included between June 2010 and November 2014 (median follow-up, 6.1 years). The reactive hyperaemia index was assessed before their discharge; reactive hyperaemia index <1.67 was defined as endothelial dysfunction. The main outcomes were the incidence of major bleeding, all-cause death, cardiovascular death, non-cardiovascular death, resuscitated cardiac arrest, non-fatal myocardial infarction, non-fatal stroke, and hospitalisation for heart failure. RESULTS: Among the included 674 patients with acute coronary syndrome, 264 (39.2%) had endothelial dysfunction. Multivariable Cox-hazard analyses revealed an independent predictive value of endothelial dysfunction for major bleeding (hazard ratio 2.29, 95% confidence interval 1.17-4.48, P = 0.016) and major adverse cardiovascular events (hazard ratio 2.04, 95% confidence interval 1.43-2.89, P < 0.001). The endothelial dysfunction group patients had a 2.5-fold greater risk of cardiovascular death; however, no association was found with non-cardiovascular death. CONCLUSION: Endothelial dysfunction assessed using reactive hyperaemia index predicted future major cardiovascular event as well as major bleeding and cardiovascular death in patients with acute coronary syndrome.

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  • Intravascular Ultrasound in Vulnerable Plaque and Acute Coronary Syndrome Invited Reviewed

    Kozo Okada, Kiyoshi Hibi

    Interventional Cardiology Clinics   12 ( 2 )   155 - 165   2023.4

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    DOI： 10.1016/j.iccl.2022.10.003

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  • Clinical impact of left ventricular systolic dysfunction in patients undergoing dialysis access surgery Reviewed

    Sanae Saka, Masaaki Konishi, Daisuke Kamimura, Hiromichi Wakui, Yasushi Matsuzawa, Kozo Okada, Jin Kirigaya, Noriaki Iwahashi, Teruyasu Sugano, Tomoaki Ishigami, Nobuhito Hirawa, Kiyoshi Hibi, Toshiaki Ebina, Kazuo Kimura, Kouichi Tamura

    Clinical and Experimental Nephrology   27 ( 4 )   374 - 381   2023.2

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  • Prognostic impact of upper and lower extremity muscle mass in heart failure. Reviewed International journal

    Masaaki Konishi, Eiichi Akiyama, Yasushi Matsuzawa, Ryosuke Sato, Shinnosuke Kikuchi, Hidefumi Nakahashi, Kozo Okada, Noriaki Iwahashi, Masami Kosuge, Toshiaki Ebina, Kiyoshi Hibi, Toshihiro Misumi, Kouichi Tamura, Kazuo Kimura

    ESC Heart Failure   10 ( 1 )   732 - 737   2023.2

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    DOI： 10.1002/ehf2.14195

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  • Impact of early intervention with alogliptin on coronary plaque regression and stabilization in patients with acute coronary syndromes Reviewed

    Kozo Okada, Shinnosuke Kikuchi, Shotaro Kuji, Naoki Nakayama, Nobuhiko Maejima, Yasushi Matsuzawa, Noriaki Iwahashi, Masami Kosuge, Toshiaki Ebina, Kazuo Kimura, Kouichi Tamura, Kiyoshi Hibi

    Atherosclerosis   360   1 - 7   2022.11

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    DOI： 10.1016/j.atherosclerosis.2022.09.005

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  • Culprit Lesion Morphology of Rapidly Progressive and Extensive Anterior-Wall ST-Segment Elevation Myocardial Infarction Reviewed International journal

    Kozo Okada, Kiyoshi Hibi, Shinnosuke Kikuchi, Hidekuni Kirigaya, Yohei Hanajima, Ryosuke Sato, Hidefumi Nakahashi, Yugo Minamimoto, Yasushi Matsuzawa, Nobuhiko Maejima, Noriaki Iwahashi, Masami Kosuge, Toshiaki Ebina, Kouichi Tamura, Kazuo Kimura

    Circulation: Cardiovascular Imaging   15 ( 11 )   e014497   2022.11

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    DOI： 10.1161/circimaging.122.014497

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  • Heterogeneous vascular response after implantation of bare nitinol self-expanding stents in the swine femoropopliteal artery. Reviewed

    Osami Kawarada, Fumiyuki Otsuka, Kojiro Miki, Masayasu Ikutomi, Kozo Okada, Soshiro Ogata, Kunihiro Nishimura, Peter J Fitzgerald, Yasuhiro Honda

    Cardiovascular Intervention and Therapeutics   2022.10

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    DOI： 10.1007/s12928-022-00889-5

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  • Influence of the cardio-ankle vascular index on chronic-phase left ventricular dysfunction after ST-segment elevation myocardial infarction. Reviewed International journal

    Jin Kirigaya, Noriaki Iwahashi, Takeru Abe, Masaomi Gohbara, Yohei Hanajima, Mutsuo Horii, Yugo Minamimoto, Kozo Okada, Yasushi Matsuzawa, Kiyoshi Hibi, Masami Kosuge, Toshiaki Ebina, Kouichi Tamura, Kazuo Kimura

    Journal of Hypertension   40 ( 8 )   1478 - 1486   2022.8

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    DOI： 10.1097/HJH.0000000000003165

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  • Post-procedural quantitative flow ratio gradient and target lesion revascularization after drug-coated balloon or plain-old balloon angioplasty. Reviewed International journal

    Hidekuni Kirigaya, Kozo Okada, Kiyoshi Hibi, Nobuhiko Maejima, Noriaki Iwahashi, Yasushi Matsuzawa, Yugo Minamimoto, Masami Kosuge, Toshiaki Ebina, Kouichi Tamura, Kazuo Kimura

    Journal of Cardiology   80 ( 6 )   511 - 517   2022.7

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    DOI： 10.1016/j.jjcc.2022.07.007

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  • Evolocumab for prevention of microvascular dysfunction in patients undergoing percutaneous coronary intervention: the randomised, open-label EVOCATION trial. Reviewed International journal

    Masaharu Ishihara, Masanori Asakura, Kiyoshi Hibi, Kozo Okada, Wataru Shimizu, Hitoshi Takano, Satoru Suwa, Kenshi Fujii, Yasuo Okumura, Toshiaki Mano, Kenichi Tsujita, Masataka Igeta, Rika Okamoto, Shinichiro Suna

    EuroIntervention   18 ( 8 )   e647-e655   2022.7

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    BACKGROUND: Statins have been shown to prevent microvascular dysfunction that may cause periprocedural myocardial infarction after percutaneous coronary intervention (PCI). Evolocumab has more potent lipid-lowering properties than statins. AIMS: The aims of this study were to investigate whether evolocumab pretreatment on top of statin therapy could prevent periprocedural microvascular dysfunction. METHODS: This study included 100 patients with stable coronary artery disease who were scheduled to undergo PCI and had high low-density lipoprotein cholesterol (LDL-C) under statin therapy. Patients were randomised to receive evolocumab 140 mg every 2 weeks for 2 to 6 weeks before PCI (evolocumab group: N=54) or not (control group: N=46). The primary endpoint was the index of microvascular resistance (IMR) after PCI. Troponin T was measured before and 24 hours after PCI. RESULTS: Geometric mean LDL-C was 94.1 (95% confidence interval [CI]: 86.8-102.1) mg/dl and 89.4 (95% CI: 83.5-95.7) mg/dl at baseline, and 25.6 (95% CI: 21.9-30.0) mg/dl and 79.8 (95% CI: 73.9-86.3) mg/dl before PCI, in the evolocumab group and in the control group, respectively. PCI was performed 22.1±8.5 days after allocation. Geometric mean IMR was 20.6 (95% CI: 17.2-24.6) in the evolocumab group and 20.6 (95% CI: 17.0-25.0) in the control group (p=0.98). There was no significant difference in the geometric mean of post-PCI troponin T (0.054, 95% CI: 0.041-0.071 ng/ml vs 0.054, 95% CI: 0.038-0.077 ng/ml; p=0.99) and in the incidence of major periprocedural myocardial infarction between the 2 groups (44.4% vs 44.2%; p=1.00). CONCLUSIONS: Evolocumab pretreatment did not prevent periprocedural microvascular dysfunction in patients on modern medical management with statins.

    DOI： 10.4244/EIJ-D-22-00269

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  • Mechanical dispersion combined with global longitudinal strain estimated by three dimensional speckle tracking in patients with ST elevation myocardial infarction. Reviewed International journal

    Noriaki Iwahashi, Jin Kirigaya, Masaomi Gohbara, Takeru Abe, Mutsuo Horii, Yohei Hanajima, Noriko Toya, Hironori Takahashi, Hidekuni Kirigaya, Yugo Minamimoto, Yuichiro Kimura, Kozo Okada, Yasushi Matsuzawa, Kiyoshi Hibi, Masami Kosuge, Toshiaki Ebina, Kouichi Tamura, Kazuo Kimura

    International Journal of Cardiology. Heart & Vasculature   40   101028 - 101028   2022.6

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    DOI： 10.1016/j.ijcha.2022.101028

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  • A Simple Risk Score to Differentiate Between Coronary Artery Obstruction and Coronary Artery Spasm of Patients With Acute Coronary Syndrome Without Persistent ST-Segment Elevation. Reviewed

    Masaomi Gohbara, Noriaki Iwahashi, Kozo Okada, Yutaka Ogino, Yohei Hanajima, Jin Kirigaya, Yugo Minamimoto, Yasushi Matsuzawa, Manabu Nitta, Masaaki Konishi, Kiyoshi Hibi, Masami Kosuge, Toshiaki Ebina, Teruyasu Sugano, Toshiyuki Ishikawa, Kouichi Tamura, Kazuo Kimura

    Circulation Journal   86 ( 10 )   1509 - 1518   2022.5

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    DOI： 10.1253/circj.CJ-22-0096

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  • Prognostic Significance of the Combination of Left Atrial Reservoir Strain and Global Longitudinal Strain Immediately After Onset of ST-Elevation Acute Myocardial Infarction. Reviewed

    Noriaki Iwahashi, Masaomi Gohbara, Jin Kirigaya, Takeru Abe, Mutsuo Horii, Yohei Hanajima, Noriko Toya, Hironori Takahashi, Yuichiro Kimura, Yugo Minamimoto, Kozo Okada, Yasushi Matsuzawa, Kiyoshi Hibi, Masami Kosuge, Toshiaki Ebina, Kouichi Tamura, Kazuo Kimura

    Circulation Journal   86 ( 10 )   1499 - 1508   2022.5

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    DOI： 10.1253/circj.CJ-21-0907

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  • Admission free-fatty acid level is a predictor of the mid-term worsening renal function in patients with ST-segment elevation myocardial infarction. Reviewed

    Masaomi Gohbara, Noriaki Iwahashi, Kozo Okada, Yugo Minamimoto, Yasushi Matsuzawa, Masaaki Konishi, Kiyoshi Hibi, Masami Kosuge, Toshiaki Ebina, Teruyasu Sugano, Toshiyuki Ishikawa, Kouichi Tamura, Kazuo Kimura

    Heart and Vessels   37 ( 5 )   720 - 729   2022.5

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    DOI： 10.1007/s00380-021-01982-0

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  • Clinical Usefulness of the Serial Examination of Three-Dimensional Global Longitudinal Strain After the Onset of ST-Elevation Acute Myocardial Infarction. Reviewed

    Noriaki Iwahashi, Mutsuo Horii, Jin Kirigaya, Takeru Abe, Masaomi Gohbara, Noriko Toya, Yohei Hanajima, Hironori Takahashi, Yugo Minamimoto, Yuichiro Kimura, Kozo Okada, Yasushi Matsuzawa, Kiyoshi Hibi, Masami Kosuge, Toshiaki Ebina, Kouichi Tamura, Kazuo Kimura

    Circulation Journal   86 ( 4 )   611 - 619   2022.3

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    DOI： 10.1253/circj.CJ-21-0815

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  • Impact of red blood cell distribution width and mean platelet volume in patients with ST-segment elevation myocardial infarction. Reviewed

    Toshiaki Ebina, Shiori Tochihara, Mai Okazaki, Kazuyo Koike, Yuko Tsuto, Megumi Tayama, Yukiko Takanami, Haruka Hirose, Mutsuo Horii, Kozo Okada, Yasushi Matsuzawa, Nobuhiko Maejima, Noriaki Iwahashi, Kiyoshi Hibi, Masami Kosuge, Kouichi Tamura, Kazuo Kimura

    Heart and Vessels   37 ( 3 )   392 - 399   2022.3

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    DOI： 10.1007/s00380-021-01936-6

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  • Clinical usefulness of left ventricular outflow tract velocity time integral for heart failure with reduced ejection fraction with rapid atrial fibrillation during landiolol treatment. Reviewed International journal

    Noriaki Iwahashi, Jin Kirigaya, Takeru Abe, Mutsuo Horii, Hironori Takahashi, Yohei Hanajima, Yuichiro Kimura, Yugo Minamimoto, Kozo Okada, Yasushi Matsuzawa, Kiyoshi Hibi, Masami Kosuge, Toshiaki Ebina, Kouichi Tamura, Kazuo Kimura

    Journal of Cardiology   79 ( 1 )   21 - 29   2022.1

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    DOI： 10.1016/j.jjcc.2021.09.008

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  • Prognostic value of comprehensive intracoronary physiology assessment early after heart transplantation Reviewed

    Jung-Min Ahn, Frederik M. Zimmermann, Satish Arora, Ole-Geir Solberg, Oskar Angeras, Katrine Rolid, Muzammil Rafique, Lars Aaberge, Kristjan Karason, Kozo Okada, Helen Luikart, Kiran K. Khush, Yasuhiro Honda, Nico H. J. Pijls, Sang Eun Lee, Jae-Joong Kim, Seung-Jung Park, Lars Gullestad, William F. Fearon

    European Heart Journal   42 ( 48 )   4918 - 4929   2021.12

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    DOI： 10.1093/eurheartj/ehab568

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  • Microcirculatory Resistance Predicts Allograft Rejection and Cardiac Events After Heart Transplantation Reviewed

    Jung-Min Ahn, Frederik M. Zimmermann, Lars Gullestad, Oskar Angeras, Kristjan Karason, Kristoffer Russell, Ketil Lunde, Kozo Okada, Helen Luikart, Kiran K. Khush, Yasuhiro Honda, Nico H. J. Pijls, Sang Eun Lee, Jae-Joong Kim, Seung-Jung Park, Ole-Geir Solberg, William F. Fearon

    Journal of the American College of Cardiology   78 ( 24 )   2425 - 2435   2021.12

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    DOI： 10.1016/j.jacc.2021.10.009

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  • Direct Oral Anticoagulant Therapy for Isolated Distal Deep Vein Thrombosis Associated with Cancer in Routine Clinical Practice. Reviewed International journal

    Yutaka Ogino, Tomoaki Ishigami, Ryosuke Sato, Hidefumi Nakahashi, Yugo Minamimoto, Yuichiro Kimura, Kozo Okada, Yasushi Matsuzawa, Noriaki Iwahashi, Kiyoshi Hibi, Masami Kosuge, Toshiaki Ebina, Toshiyuki Ishikawa, Kouichi Tamura, Kazuo Kimura

    Journal of Clinical Medicine   10 ( 20 )   2021.10

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    DOI： 10.3390/jcm10204648

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  • Impact of sarcopenic obesity on long-term clinical outcomes after ST-segment elevation myocardial infarction Reviewed

    Ryosuke Sato, Kozo Okada, Eiichi Akiyama, Masaaki Konishi, Yasushi Matsuzawa, Hidefumi Nakahashi, Yugo Minamimoto, Yuichiro Kimura, Nobuhiko Maejima, Noriaki Iwahashi, Kiyoshi Hibi, Masami Kosuge, Toshiaki Ebina, Kouichi Tamura, Kazuo Kimura

    Atherosclerosis   335   135 - 141   2021.10

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    DOI： 10.1016/j.atherosclerosis.2021.08.038

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  • Long-Term Results up to 12 Months After Catheter-Based Alcohol-Mediated Renal Denervation for Treatment of Resistant Hypertension Reviewed

    Felix Mahfoud, Horst Sievert, Stefan Bertog, Lucas Lauder, Sebastian Ewen, Jean-Philippe Lengelé, Wojciech Wojakowski, Roland Schmieder, Markus van der Giet, Michael A. Weber, David E. Kandzari, Helen Parise, Tim A. Fischell, Atul Pathak, Alexandre Persu

    Circulation: Cardiovascular Interventions   14 ( 9 )   2021.9

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    Background:

    Primary results of this prospective, open-label, multicenter trial suggested that alcohol-mediated renal denervation with perivascular injection of dehydrated alcohol using the Peregrine System Infusion Catheter safely reduces blood pressure (BP) in patients with resistant hypertension. To date, maintenance of the BP-lowering effect beyond 6 months using this novel technology has not been reported. This article describes the final, 12-month follow-up data on the safety and efficacy of alcohol-mediated renal denervation in these patients.

    Methods:

    Forty-five patients with resistant hypertension on a stable regimen of on average 5.1±1.5 antihypertensive medications underwent successful bilateral renal denervation using the Peregrine Catheter with alcohol as the neurolytic agent (0.6 mL per renal artery). Apart from 2 vascular access pseudoaneurysms (both without sequelae), no major procedural complications occurred.

    Results:

    At 12 months post-procedure, mean 24-hour ambulatory systolic and diastolic BP were reduced by 10 mm Hg (95% CI, −16 to −5) and 7 mm Hg (−10 to −3), respectively ( P &lt;0.001). Office systolic/diastolic BP was reduced by 20/10 mm Hg (−27, −13/−14, −6; &lt;0.001). Compared with baseline, the number of antihypertensive medications was reduced in 21% of patients, while it was increased in 19%. From baseline to 12 months, serum creatinine, urea, cystatin C, and spot urine albumin levels remained unchanged. The change in estimated glomerular filtration rates (−3.9±10.3 mL/minute per 1.73 m <sup>2</sup> [95% CI, −7.1 to −0.75]; P =0.02) was within the expected range. There were no cases of renal artery stenosis up to 12-month follow-up.

    Conclusions:

    Catheter-based chemical renal denervation with dehydrated alcohol using the Peregrine Catheter seems to safely reduce BP at follow-up of up to 12 months. Further randomized and sham controlled studies are underway to further validate these findings.

    Registration:

    URL: https://www.clinicaltrials.gov ; Unique identifier: NCT02570113.

    DOI： 10.1161/circinterventions.120.010075

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  • Clinical Significance of Late Diastolic Tissue Doppler Velocity at 24 Hours or 14 Days After Onset of ST-Elevation Acute Myocardial Infarction. Reviewed

    Noriaki Iwahashi, Masaomi Gohbara, Takeru Abe, Jin Kirigaya, Mutsuo Horii, Yohei Hanajima, Hironori Takahashi, Yugo Minamimoto, Yuichiro Kimura, Eiichi Akiyama, Kozo Okada, Yasushi Matsuzawa, Nobuhiko Maejima, Kiyoshi Hibi, Toshiaki Ebina, Masami Kosuge, Kouichi Tamura, Kazuo Kimura

    Circulation Reports   3 ( 7 )   396 - 404   2021.7

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    Background: The significance of late diastolic velocity (a') obtained by tissue Doppler imaging (TDI), which reveals atrial function, in ST-elevation myocardial infarction (STEMI) remains unclear. This study evaluated the association of TDI parameters determined either immediately or 2 weeks after percutaneous coronary intervention (PCI) with long-term outcomes. Methods and Results: In all, 740 patients with first-time STEMI underwent immediate PCI (i.e., within 12 h of onset). Echocardiography was performed in 307 patients 2 weeks after onset (Group A; mean age 64 years, 249 males), in 277 patients immediately after PCI (Group B; mean age 65 years, 229 males), and in 156 patients twice (i.e., immediately and 2 weeks after PCI; Group C; mean age 65 years, 135 males). Patients were followed-up for up to 10 years (mean 81 months). The primary endpoints were cardiac death or heart failure hospitalization. Major adverse cardiovascular events (MACE) occurred in 143 patients (19%) during the follow-up period. Both univariate and multivariate Cox hazard analyses were used to determine predictors of MACE. At 24 h and 2 weeks after STEMI onset, a' and E/e' were the strongest predictors of MACE, respectively. Conclusions: TDI parameters have different implications depending on the timing of echocardiography after a first-time STEMI. Based on the results of this study, atrial dysfunction measured by TDI 24 h after STEMI onset may indicate a poor prognosis.

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  • Skeletal muscle mass is associated with glycemic variability in patients with ST-segment elevation myocardial infarction. Reviewed

    Masaomi Gohbara, Noriaki Iwahashi, Ryosuke Sato, Eiichi Akiyama, Masaaki Konishi, Hidefumi Nakahashi, Shunsuke Kataoka, Hironori Takahashi, Jin Kirigaya, Yugo Minamimoto, Kozo Okada, Yasushi Matsuzawa, Nobuhiko Maejima, Kiyoshi Hibi, Masami Kosuge, Toshiaki Ebina, Teruyasu Sugano, Toshiyuki Ishikawa, Kouichi Tamura, Kazuo Kimura

    Heart and Vessels   36 ( 7 )   945 - 954   2021.7

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  • Global Strain Measured by Three-Dimensional Speckle Tracking Echocardiography Is a Useful Predictor for 10-Year Prognosis After a First ST-Elevation Acute Myocardial Infarction. Reviewed

    Noriaki Iwahashi, Jin Kirigaya, Masaomi Gohbara, Takeru Abe, Mutsuo Horii, Yohei Hanajima, Noriko Toya, Hironori Takahashi, Yugo Minamimoto, Yuichiro Kimura, Eiichi Akiyama, Kozo Okada, Yasushi Matsuzawa, Nobuhiko Maejima, Kiyoshi Hibi, Masami Kosuge, Toshiaki Ebina, Kouichi Tamura, Kazuo Kimura

    Circulation Journal   85 ( 10 )   1735 - 1743   2021.6

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  • Diagnostic performance and limitation of quantitative flow ratio for functional assessment of intermediate coronary stenosis Reviewed International journal

    Hidekuni Kirigaya, Kozo Okada, Kiyoshi Hibi, Nobuhiko Maejima, Noriaki Iwahashi, Yasushi Matsuzawa, Eiichi Akiyama, Yugo Minamimoto, Masami Kosuge, Toshiaki Ebina, Kouichi Tamura, Kazuo Kimura

    Journal of Cardiology   77 ( 5 )   492 - 499   2021.5

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  • Intravascular ultrasound predictors of long-term outcomes following ABSORB bioresorbable scaffold implantation: A pooled analysis of the ABSORB III and ABSORB Japan trials Reviewed International journal

    Takeshi Nishi, Kozo Okada, Hideki Kitahara, Ryo Kameda, Masayasu Ikutomi, Shinji Imura, M. Brooke Hollak, Paul G. Yock, Jeffrey J. Popma, Hajime Kusano, Wai-Fung Cheong, Krishnankutty Sudhir, Peter J. Fitzgerald, Stephen G. Ellis, Dean J. Kereiakes, Gregg W. Stone, Yasuhiro Honda, Takeshi Kimura

    Journal of Cardiology   78 ( 3 )   224 - 229   2021.4

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  • Characteristics and Prognosis of Patients with Vasospastic Angina Diagnosed by a Provocation Test with Secondary Prevention Implantable Cardioverter Defibrillator Reviewed

    Yutaka Ogino, Toshiyuki Ishikawa, Yugo Minamimoto, Masayoshi Kiyokuni, Yuichiro Kimura, Eiichi Akiyama, Kozo Okada, Masaaki Konishi, Junya Hosoda, Yasushi Matsuzawa, Nobuhiko Maejima, Noriaki Iwahashi, Katsumi Matsumoto, Kiyoshi Hibi, Masami Kosuge, Toshiaki Ebina, Kouichi Tamura, Kazuo Kimura

    International Heart Journal   62 ( 2 )   224 - 229   2021.3

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  • Clinical impact of admission urinary 8-hydroxydeoxyguanosine level for predicting cardiovascular mortality in patients with acute coronary syndrome Reviewed

    Masaomi Gohbara, Noriaki Iwahashi, Hidefumi Nakahashi, Shunsuke Kataoka, Hironori Takahashi, Jin Kirigaya, Yugo Minamimoto, Eiichi Akiyama, Kozo Okada, Yasushi Matsuzawa, Masaaki Konishi, Nobuhiko Maejima, Kiyoshi Hibi, Masami Kosuge, Toshiaki Ebina, Teruyasu Sugano, Toshiyuki Ishikawa, Kouichi Tamura, Kazuo Kimura

    Heart and Vessels   36 ( 1 )   38 - 47   2021.1

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    DOI： 10.1007/s00380-020-01663-4

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  • Decreased Appendicular Skeletal Muscle Mass is Associated with Poor Outcomes after ST-Segment Elevation Myocardial Infarction Reviewed

    Ryosuke Sato, Eiichi Akiyama, Masaaki Konishi, Yasushi Matsuzawa, Hiroyuki Suzuki, Chika Kawashima, Yuichiro Kimura, Kozo Okada, Nobuhiko Maejima, Noriaki Iwahashi, Kiyoshi Hibi, Masami Kosuge, Toshiaki Ebina, Stephan von Haehling, Stefan D. Anker, Kouichi Tamura, Kazuo Kimura

    Journal of Atherosclerosis and Thrombosis   27 ( 12 )   1278 - 1287   2020.12

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  • Bioresorbable vascular scaffolds versus everolimus-eluting stents: a biomechanical analysis of the ABSORB III Imaging substudy Reviewed

    Arnav Kumar, Bill D. Gogas, Elizabeth W. Thompson, Grady Murphy Burne, David Molony, Hossein Hosseini, Karthic Chandran, Adrien Lefieux, Yasuhiro Honda, Joo Myung Lee, Patrick W. Serruys, Dean J. Kereiakes, Gregg W. Stone, Habib Samady. Collaborators, Mohamad Raad, Sonu Gupta, David G. Sternheim, Spencer B. King III, Kozo Okada, Richard, J. Rapoza, Charles A. Simonton, Don P. Giddens, Alessandro Veneziani, Stephen G. Ellis

    EuroIntervention   16 ( 12 )   e989 - e996   2020.12

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    DOI： 10.4244/eij-d-19-01128

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  • Scaffold underexpansion and late lumen loss after bioresorbable scaffold implantation: Insights from ABSORB JAPAN trial. Reviewed International journal

    Kozo Okada, Yasuhiro Honda, Hideki Kitahara, Masayasu Ikutomi, Ryo Kameda, M Brooke Hollak, Paul G Yock, Jeffrey J Popma, Hajime Kusano, Wai-Fung Cheong, Krishnankutty Sudhir, Peter J Fitzgerald, Takeshi Kimura

    International Journal of Cardiology. Heart & Vasculature   31   100623 - 100623   2020.12

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  • Impact of Myocardial Bridge on Life‐Threatening Ventricular Arrhythmia in Patients With Implantable Cardioverter Defibrillator Reviewed International journal

    Kozo Okada, Kiyoshi Hibi, Yutaka Ogino, Nobuhiko Maejima, Shinnosuke Kikuchi, Hidekuni Kirigaya, Jin Kirigaya, Ryosuke Sato, Hidefumi Nakahashi, Yugo Minamimoto, Yuichiro Kimura, Eiichi Akiyama, Yasushi Matsuzawa, Noriaki Iwahashi, Masami Kosuge, Toshiaki Ebina, Kouichi Tamura, Kazuo Kimura

    Journal of the American Heart Association   9 ( 21 )   e017455   2020.11

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    DOI： 10.1161/jaha.120.017455

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  • Prognostic Significance of a Combination of QRS Score and E/e′ Obtained 2 Weeks After the Onset of ST-Elevation Myocardial Infarction Reviewed

    Noriaki Iwahashi, Masaomi Gohbara, Jin Kirigaya, Takeru Abe, Mutsuo Horii, Hironori Takahashi, Masami Kosuge, Yohei Hanajima, Eiichi Akiyama, Kozo Okada, Yasushi Matsuzawa, Nobuhiko Maejima, Kiyoshi Hibi, Toshiaki Ebina, Kouichi Tamura, Kazuo Kimura

    Circulation Journal   84 ( 11 )   1965 - 1973   2020.10

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  • Impact of three-dimensional global longitudinal strain for patients with acute myocardial infarction Reviewed International journal

    Noriaki Iwahashi, Jin Kirigaya, Takeru Abe, Mutsuo Horii, Noriko Toya, Yohei Hanajima, Hironori Takahashi, Eiichi Akiyama, Kozo Okada, Yasushi Matsuzawa, Nobuhiko Maejima, Kiyoshi Hibi, Masami Kosuge, Toshiaki Ebina, Kouichi Tamura, Kazuo Kimura

    European Heart Journal - Cardiovascular Imaging   22 ( 12 )   1413 - 1424   2020.9

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    DOI： 10.1093/ehjci/jeaa241

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  • Intravascular ultrasound radiofrequency signal analysis of blood speckles: Physiological assessment of intermediate coronary artery stenosis Reviewed International journal

    Kozo Okada, Kiyoshi Hibi, Kensuke Matsushita, Hiroyuki Yagami, Kouichi Tamura, Yasuhiro Honda, Kazuo Kimura

    Catheterization and Cardiovascular Interventions   96 ( 2 )   E155 - E164   2020.8

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  • Direct Oral Anticoagulant Therapy for Cancer-Associated Venous Thromboembolism in Routine Clinical Practice Reviewed

    Yutaka Ogino, Tomoaki Ishigami, Yugo Minamimoto, Yuichiro Kimura, Eiichi Akiyama, Kozo Okada, Yasushi Matsuzawa, Nobuhiko Maejima, Noriaki Iwahashi, Kiyoshi Hibi, Masami Kosuge, Toshiaki Ebina, Toshiyuki Ishikawa, Kouichi Tamura, Kazuo Kimura

    Circulation Journal   84 ( 8 )   1330 - 1338   2020.7

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  • Impact of Cardio-Ankle Vascular Index on Long-Term Outcome in Patients with Acute Coronary Syndrome Reviewed

    Jin Kirigaya, Noriaki Iwahashi, Hironori Tahakashi, Yugo Minamimoto, Masaomi Gohbara, Takeru Abe, Eiichi Akiyama, Kozo Okada, Yasushi Matsuzawa, Nobuhiko Maejima, Kiyoshi Hibi, Masami Kosuge, Toshiaki Ebina, Kouichi Tamura, Kazuo Kimura

    Journal of Atherosclerosis and Thrombosis   27 ( 7 )   657 - 668   2020.7

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  • Coronary arteritis: a case series Reviewed International journal

    Shinnosuke Kikuchi, Kozo Okada, Kiyoshi Hibi, Nobuhiko Maejima, Naoto Yabu, Keiji Uchida, Kouichi Tamura, Kazuo Kimura

    European Heart Journal - Case Reports   4 ( 2 )   1 - 6   2020.6

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  • Association between abdominal fat distribution and coronary plaque instability in patients with acute coronary syndrome Reviewed International journal

    Kozo Okada, Kiyoshi Hibi, Yasuhiro Honda, Peter J. Fitzgerald, Kouichi Tamura, Kazuo Kimura

    Nutrition, Metabolism and Cardiovascular Diseases   30 ( 7 )   1169 - 1178   2020.6

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    DOI： 10.1016/j.numecd.2020.03.017

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  • Platelet-Derived Thrombogenicity Measured by Total Thrombus-Formation Analysis System in Patients With ST-Segment Elevation Myocardial Infarction Undergoing Primary Percutaneous Coronary Intervention Reviewed

    Shinnosuke Kikuchi, Kengo Tsukahara, Shinya Ichikawa, Takeru Abe, Yugo Minamimoto, Yuichiro Kimura, Eiichi Akiyama, Naoki Nakayama, Kozo Okada, Yasushi Matsuzawa, Masaaki Konishi, Nobuhiko Maejima, Noriaki Iwahashi, Kiyoshi Hibi, Masami Kosuge, Toshiaki Ebina, Kouichi Tamura, Kazuo Kimura

    Circulation Journal   84 ( 6 )   975 - 984   2020.5

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  • Long-term clinical outcomes with use of an angiotensin-converting enzyme inhibitor early after heart transplantation Reviewed International journal

    Hiroyuki Arashi, Takuma Sato, Jon Kobashigawa, Helen Luikart, Yuhei Kobayashi, Kozo Okada, Seema Sinha, Yasuhiro Honda, Alan C. Yeung, Kiran Khush, William F. Fearon

    American Heart Journal   222   30 - 37   2020.4

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  • Alcohol-Mediated Renal Denervation Using the Peregrine System Infusion Catheter for Treatment of Hypertension Reviewed

    Felix Mahfoud, Jean Renkin, Horst Sievert, Stefan Bertog, Sebastian Ewen, Michael Böhm, Jean-Philippe Lengelé, Wojciech Wojakowski, Roland Schmieder, Markus van der Giet, Helen Parise, Nicole Haratani, Atul Pathak, Alexandre Persu

    JACC: Cardiovascular Interventions   13 ( 4 )   471 - 484   2020.2

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  • Randomized Comparison Between Everolimus-Eluting Bioresorbable Scaffold and Metallic Stent Reviewed International journal

    Yoshinobu Onuma, Yasuhiro Honda, Taku Asano, Hiroki Shiomi, Ken Kozuma, Yukio Ozaki, Atsuo Namiki, Satoshi Yasuda, Takafumi Ueno, Kenji Ando, Jungo Furuya, Keiichi Igarashi Hanaoka, Kengo Tanabe, Kozo Okada, Hideki Kitahara, Masafumi Ono, Hajime Kusano, Richard Rapoza, Charles Simonton, Jeffrey J. Popma, Gregg W. Stone, Peter J. Fitzgerald, Patrick W. Serruys, Takeshi Kimura

    JACC: Cardiovascular Interventions   13 ( 1 )   116 - 127   2020.1

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  • Peak systolic velocity ratio derived from quantitative vessel analysis for restenosis after femoropopliteal intervention: a multidisciplinary review from Endovascular Asia Reviewed

    Osami Kawarada, Koji Hozawa, Kan Zen, Hsuan-Li Huang, Su Hong Kim, Donghoon Choi, Kihyuk Park, Kenichi Kato, Taku Kato, Yoshinori Tsubakimoto, Shigeo Ichihashi, Naoki Fujimura, Akihiro Higashimori, Tomoyasu Sato, Bryan Ping-Yen Yan, Skyi Yin-Chun Pang, Chumpol Wongwanit, Yew Pung Leong, Benjamin Chua, Robbie K. George, I-Chih Chen, Jen-Kuang Lee, Chung-Ho Hsu, Uei Pua, Yo Iwata, Kojiro Miki, Kozo Okada, Hideaki Obara

    Cardiovascular Intervention and Therapeutics   35 ( 1 )   52 - 61   2020.1

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    DOI： 10.1007/s12928-019-00602-z

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  • Microbiota-derived Trimethylamine N-oxide Predicts Cardiovascular Risk After STEMI Reviewed

    Yasushi Matsuzawa, Hidefumi Nakahashi, Masaaki Konishi, Ryosuke Sato, Chika Kawashima, Shinnosuke Kikuchi, Eiichi Akiyama, Noriaki Iwahashi, Nobuhiko Maejima, Kozo Okada, Toshiaki Ebina, Kiyoshi Hibi, Masami Kosuge, Tomoaki Ishigami, Kouichi Tamura, Kazuo Kimura

    Scientific Reports   9 ( 1 )   11647   2019.12

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    DOI： 10.1038/s41598-019-48246-6

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  • Urgent Control of Rapid Atrial Fibrillation by Landiolol in Patients With Acute Decompensated Heart Failure With Severely Reduced Ejection Fraction Reviewed

    Noriaki Iwahashi, Hironori Takahashi, Takeru Abe, Kozo Okada, Eiichi Akiyama, Yasushi Matsuzawa, Masaaki Konishi, Nobuhiko Maejima, Kiyoshi Hibi, Masami Kosuge, Toshiaki Ebina, Kouichi Tamura, Kazuo Kimura

    Circulation Reports   1 ( 10 )   422 - 430   2019.10

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    Background: We investigated the clinical usefulness of landiolol for rapid atrial fibrillation (AF) in patients with acute decompensated heart failure (ADHF) and identify the patients eligible for landiolol. Methods and Results: A total of 101 ADHF patients with reduced ejection fraction (HFrEF) with rapid AF were enrolled. Immediately after admission, an initial dose of landiolol was given (1 μg/kg-1/min-1), and then the dose was increased to decrease heart rate (HR) to <110 beats/min and change HR (∆HR) >20% in ≤24 h. Thirty-seven were monitored using right heart catheterization at 3 points (baseline, 1 μg/kg-1/min-1, and maximum dose). We checked the major adverse events (MAE) during initial hospitalization, which included cardiac death, HF prolongation (required i.v. treatment at 30 days), and worsening renal function. The average maximum dose of landiolol was 3.8±2.3 μg/kg-1/min-1. HR (P<0.0001) and pulmonary capillary wedge pressure (P=0.0008) decreased safely. MAE occurred in 39 patients. The patients with left ventricular (LV) end-diastolic volume index <84.0 mL/m2 and mean blood pressure (mean BP) >97 mmHg had less frequent MAE (P<0.0001). Conclusions: Landiolol was effective for safely controlling rapid AF in patients with HFrEF with ADHF, leading to hemodynamic improvement and avoidance of short-term MAE, especially in patients with relatively smaller LV and higher BP.

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  • Early invasive assessment of the coronary microcirculation predicts subsequent acute rejection after heart transplantation Reviewed

    Kozo Okada, Yasuhiro Honda, Helen Luikart, Paul G. Yock, Peter J. Fitzgerald, Alan C. Yeung, Hannah A. Valantine, Kiran K. Khush, William F. Fearon

    International Journal of Cardiology   290   27 - 32   2019.9

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  • Acute anterior myocardial infarction with pectus carinatum Reviewed

    Shinnosuke Kikuchi, Hidefumi Nakahashi, Yuichiro Kimura, Eiichi Akiyama, Kozo Okada, Yasushi Matsuzawa, Masaaki Konishi, Nobuhiko Maejima, Noriaki Iwahashi, Kiyoshi Hibi, Masami Kosuge, Toshiaki Ebina, Kouichi Tamura, Kazuo Kimura

    Journal of Electrocardiology   55   51 - 53   2019.7

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  • Comparison between instantaneous wave-free ratio versus morphometric assessments by intracoronary imaging Reviewed

    Kensuke Matsushita, Kiyoshi Hibi, Kozo Okada, Kentaro Sakamaki, Eiichi Akiyama, Yuichiro Kimura, Yasushi Matsuzawa, Nobuhiko Maejima, Noriaki Iwahashi, Kengo Tsukahara, Masami Kosuge, Toshiaki Ebina, Peter J. Fitzgerald, Yasuhiro Honda, Kouichi Tamura, Kazuo Kimura

    Heart and Vessels   34 ( 6 )   926 - 935   2019.6

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  • Impact of Total Antithrombotic Effect on Bleeding Complications in Patients Receiving Multiple Antithrombotic Agents Reviewed

    Shinya Ichikawa, Kengo Tsukahara, Shinnosuke Kikuchi, Yugo Minamimoto, Yuichiro Kimura, Kozo Okada, Yasushi Matsuzawa, Masaaki Konishi, Nobuhiko Maejima, Noriaki Iwahashi, Kiyoshi Hibi, Masami Kosuge, Toshiaki Ebina, Kouichi Tamura, Kazuo Kimura

    Circulation Journal   83 ( 6 )   1309 - 1316   2019.5

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  • Cardiac function response to stenting in atherosclerotic renal artery disease with and without heart failure: results from the Carmel study Reviewed

    Osami Kawarada, Teruyoshi Kume, Kan Zen, Shigeru Nakamura, Koji Hozawa, Tadafumi Akimitsu, Hiroshi Asano, Hiroshi Ando, Yoshito Yamamoto, Takehiro Yamashita, Norihiko Shinozaki, Keita Odashiro, Tadaya Sato, Kenichiro Yuba, Yuji Sakanoue, Takashi Uzu, Kozo Okada, Peter J. Fitzgerald, Yasuhiro Honda, Satoshi Yasuda

    ESC Heart Failure   6 ( 2 )   319 - 327   2019.4

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  • Association of Endothelin-1 With Accelerated Cardiac Allograft Vasculopathy and Late Mortality Following Heart Transplantation Reviewed

    Rushi V. Parikh, Kiran Khush, Vedant S. Pargaonkar, Helen Luikart, David Grimm, Michelle Yu, Kozo Okada, Yasuhiro Honda, Alan C. Yeung, Hannah Valantine, William F. Fearon

    Journal of Cardiac Failure   25 ( 2 )   97 - 104   2019.2

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  • Myocardial Infarction Caused by Accelerated Plaque Formation Related to Myocardial Bridge in a Young Man Reviewed International journal

    Shinnosuke Kikuchi, Kozo Okada, Kiyoshi Hibi, Nobuhiko Maejima, Yasushi Matsuzawa, Masaaki Konishi, Yuichiro Kimura, Masami Kosuge, Noriaki Iwahashi, Toshiaki Ebina, Kouichi Tamura, Kazuo Kimura

    Canadian Journal of Cardiology   34 ( 12 )   1687.e13 - 1687.e15   2018.12

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  • Surgical unroofing of hemodynamically significant myocardial bridges in a pediatric population Reviewed

    Katsuhide Maeda, Ingela Schnittger, Daniel J. Murphy, Jennifer A. Tremmel, Jack H. Boyd, Lynn Peng, Kozo Okada, Vedant S. Pargaonkar, Frank L. Hanley, Robert Scott Mitchell, Ian S. Rogers

    The Journal of Thoracic and Cardiovascular Surgery   156 ( 4 )   1618 - 1626   2018.10

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  • Glycemic variability determined with a continuous glucose monitoring system can predict prognosis after acute coronary syndrome. Reviewed International journal

    Hironori Takahashi, Noriaki Iwahashi, Jin Kirigaya, Shunsuke Kataoka, Yugo Minamimoto, Masaomi Gohbara, Takeru Abe, Kozo Okada, Yasushi Matsuzawa, Masaaki Konishi, Nobuhiko Maejima, Kiyoshi Hibi, Masami Kosuge, Toshiaki Ebina, Kouichi Tamura, Kazuo Kimura

    Cardiovascular Diabetology   17 ( 1 )   116 - 116   2018.8

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  • Assessment of bioresorbable scaffold with a novel high-definition 60 MHz IVUS imaging system: Comparison with 40-MHz IVUS referenced to optical coherence tomography Reviewed International journal

    Kozo Okada, Hideki Kitahara, Yoshiaki Mitsutake, Shigemitsu Tanaka, Takumi Kimura, Paul G. Yock, Peter J. Fitzgerald, Fumiaki Ikeno, Yasuhiro Honda

    Catheterization and Cardiovascular Interventions   91 ( 5 )   874 - 883   2018.4

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  • Bioresorbable Scaffold for Treatment of Coronary Artery Lesions Reviewed International journal

    Kozo Okada, Yasuhiro Honda, Hideki Kitahara, Kyuhachi Otagiri, Shigemitsu Tanaka, M. Brooke Hollak, Paul G. Yock, Jeffrey J. Popma, Hajime Kusano, Wai-Fung Cheong, Krishnankutty Sudhir, Peter J. Fitzgerald, Takeshi Kimura

    JACC: Cardiovascular Interventions   11 ( 7 )   648 - 661   2018.4

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    DOI： 10.1016/j.jcin.2017.11.034

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  • Impact of Stent Size Selection on Acute and Long-Term Outcomes After Drug-Eluting Stent Implantation in De Novo Coronary Lesions Reviewed International journal

    Hideki Kitahara, Kozo Okada, Takumi Kimura, Paul G. Yock, Alexandra J. Lansky, Jeffrey J. Popma, Alan C. Yeung, Peter J. Fitzgerald, Yasuhiro Honda

    Circulation: Cardiovascular Interventions   10 ( 10 )   e004795   2017.10

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    DOI： 10.1161/circinterventions.116.004795

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  • Angiotensin-Converting Enzyme Inhibition Early After Heart Transplantation Reviewed

    William F. Fearon, Kozo Okada, Jon A. Kobashigawa, Yuhei Kobayashi, Helen Luikart, Sean Sana, Tiffany Daun, Steven A. Chmura, Seema Sinha, Garett Cohen, Yasuhiro Honda, Michael Pham, David B. Lewis, Daniel Bernstein, Alan C. Yeung, Hannah A. Valantine, Kiran Khush

    Journal of the American College of Cardiology   69 ( 23 )   2832 - 2841   2017.6

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    DOI： 10.1016/j.jacc.2017.03.598

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  • Coronary Endothelial Dysfunction and the Index of Microcirculatory Resistance as a Marker of Subsequent Development of Cardiac Allograft Vasculopathy Reviewed

    Jang Hoon Lee, Kozo Okada, Kiran Khush, Yuhei Kobayashi, Seema Sinha, Helen Luikart, Hannah Valantine, Alan C. Yeung, Yasuhiro Honda, William F. Fearon

    Circulation   135 ( 11 )   1093 - 1095   2017.3

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    DOI： 10.1161/circulationaha.116.025268

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  • Attenuated-Signal Plaque Progression Predicts Long-Term Mortality After Heart Transplantation Reviewed International journal

    Kozo Okada, William F. Fearon, Helen Luikart, Hideki Kitahara, Kyuhachi Otagiri, Shigemitsu Tanaka, Takumi Kimura, Paul G. Yock, Peter J. Fitzgerald, Alan C. Yeung, Hannah A. Valantine, Kiran K. Khush, Yasuhiro Honda

    Journal of the American College of Cardiology   68 ( 4 )   382 - 392   2016.7

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    DOI： 10.1016/j.jacc.2016.05.028

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  • Acute stent recoil and optimal balloon inflation strategy: an experimental study using real-time optical coherence tomography Reviewed International journal

    Hideki Kitahara, Katsuhisa Waseda, Ryotaro Yamada, Kyuhachi Otagiri, Shigemitsu Tanaka, Yuhei Kobayashi, Kozo Okada, Teruyoshi Kume, Kaori Nakagawa, Tomohiko Teramoto, Fumiaki Ikeno, Paul G. Yock, Peter J. Fitzgerald, Yasuhiro Honda

    EuroIntervention   12 ( 2 )   e190 - e198   2016.6

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    DOI： 10.4244/eijv12i2a32

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  • Association of periarterial neovascularization with progression of cardiac allograft vasculopathy and long-term clinical outcomes in heart transplant recipients Reviewed International journal

    Hideki Kitahara, Kozo Okada, Shigemitsu Tanaka, Hyoung-Mo Yang, Kojiro Miki, Yuhei Kobayashi, Takumi Kimura, Helen Luikart, Paul G. Yock, Alan C. Yeung, Peter J. Fitzgerald, Kiran K. Khush, William F. Fearon, Yasuhiro Honda

    The Journal of Heart and Lung Transplantation   35 ( 6 )   752 - 759   2016.6

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    DOI： 10.1016/j.healun.2016.02.002

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  • Intravascular Ultrasound-Derived Stent Dimensions as Predictors of Angiographic Restenosis Following Nitinol Stent Implantation in the Superficial Femoral Artery Reviewed

    Kojiro Miki, Kenichi Fujii, Daizo Kawasaki, Masahiko Shibuya, Masashi Fukunaga, Takahiro Imanaka, Hiroto Tamaru, Akinori Sumiyoshi, Machiko Nishimura, Tetsuo Horimatsu, Ten Saita, Kozo Okada, Takumi Kimura, Yasuhiro Honda, Peter J. Fitzgerald, Tohru Masuyama, Masaharu Ishihara

    Journal of Endovascular Therapy   23 ( 3 )   424 - 432   2016.6

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    DOI： 10.1177/1526602816641669

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    Other Link： http://journals.sagepub.com/doi/full-xml/10.1177/1526602816641669

  • Invasive Assessment of Coronary Physiology Predicts Late Mortality After Heart Transplantation Reviewed

    Hyoung-Mo Yang, Kiran Khush, Helen Luikart, Kozo Okada, Hong-Seok Lim, Yuhei Kobayashi, Yasuhiro Honda, Alan C. Yeung, Hannah Valantine, William F. Fearon

    Circulation   133 ( 20 )   1945 - 1950   2016.5

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    DOI： 10.1161/CIRCULATIONAHA.115.018741

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  • Quantitative precision of optical frequency domain imaging: direct comparison with frequency domain optical coherence tomography and intravascular ultrasound Reviewed

    Yuhei Kobayashi, Hideki Kitahara, Shigemitsu Tanaka, Kozo Okada, Takumi Kimura, Fumiaki Ikeno, Paul G. Yock, Peter J. Fitzgerald, Yasuhiro Honda

    Cardiovascular Intervention and Therapeutics   31 ( 2 )   79 - 88   2016.4

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    Language：English   Publishing type：Research paper (scientific journal)  

    DOI： 10.1007/s12928-015-0349-x

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    Other Link： http://link.springer.com/article/10.1007/s12928-015-0349-x/fulltext.html

  • Paradoxical Vessel Remodeling of the Proximal Segment of the Left Anterior Descending Artery Predicts Long-Term Mortality After Heart Transplantation Reviewed

    Kozo Okada, Hideki Kitahara, Hyoung-Mo Yang, Shigemitsu Tanaka, Yuhei Kobayashi, Takumi Kimura, Helen Luikart, Paul G. Yock, Alan C. Yeung, Hannah A. Valantine, Peter J. Fitzgerald, Khan K. Khush, Yasuhiro Honda, William F. Fearon

    JACC: Heart Failure   3 ( 12 )   942 - 952   2015.12

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    DOI： 10.1016/j.jchf.2015.07.013

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  • Association between blood glucose variability and coronary plaque instability in patients with acute coronary syndromes Reviewed

    Kozo Okada, Kiyoshi Hibi, Masaomi Gohbara, Shunsuke Kataoka, Keiko Takano, Eiichi Akiyama, Yasushi Matsuzawa, Kenichiro Saka, Nobuhiko Maejima, Mitsuaki Endo, Noriaki Iwahashi, Kengo Tsukahara, Masami Kosuge, Toshiaki Ebina, Peter J. Fitzgerald, Yasuhiro Honda, Satoshi Umemura, Kazuo Kimura

    Cardiovascular Diabetology   14 ( 1 )   2015.8

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    DOI： 10.1186/s12933-015-0275-3

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  • Relation Between the SYNTAX Score and Culprit Vessel Vulnerability in Non–ST-Segment Elevation Acute Coronary Syndrome Reviewed International journal

    Kenichiro Saka, Kiyoshi Hibi, Ken Kozuma, Nobuhiko Maejima, Kozo Okada, Yasushi Matsuzawa, Mitsuaki Endo, Noriaki Iwahashi, Kengo Tsukahara, Masami Kosuge, Toshiaki Ebina, Satoshi Umemura, Kazuo Kimura

    JACC: Cardiovascular Imaging   8 ( 4 )   496 - 498   2015.4

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    DOI： 10.1016/j.jcmg.2014.07.022

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  • Association Between Gait Speed as a Measure of Frailty and Risk of Cardiovascular Events After Myocardial Infarction Reviewed

    Yasushi Matsuzawa, Masaaki Konishi, Eiichi Akiyama, Hiroyuki Suzuki, Naoki Nakayama, Masayoshi Kiyokuni, Shinichi Sumita, Toshiaki Ebina, Masami Kosuge, Kiyoshi Hibi, Kengo Tsukahara, Noriaki Iwahashi, Mitsuaki Endo, Nobuhiko Maejima, Kenichiro Saka, Katsutaka Hashiba, Kozo Okada, Masataka Taguri, Satoshi Morita, Seigo Sugiyama, Hisao Ogawa, Hironobu Sashika, Satoshi Umemura, Kazuo Kimura

    Journal of the American College of Cardiology   61 ( 19 )   1964 - 1972   2013.5

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    DOI： 10.1016/j.jacc.2013.02.020

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  • Differences in negative T waves among acute coronary syndrome, acute pulmonary embolism, and Takotsubo cardiomyopathy Reviewed

    Masami Kosuge, Toshiaki Ebina, Kiyoshi Hibi, Kengo Tsukahara, Noriaki Iwahashi, Masaomi Gohbara, Yasushi Matsuzawa, Kozo Okada, Satoshi Morita, Satoshi Umemura, Kazuo Kimura

    European Heart Journal: Acute Cardiovascular Care   1 ( 4 )   349 - 357   2012.12

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    DOI： 10.1177/2048872612466790

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  • Long-term effects of ezetimibe-plus-statin therapy on low-density lipoprotein cholesterol levels as compared with double-dose statin therapy in patients with coronary artery disease Reviewed

    Kozo Okada, Noriaki Iwahashi, Tsutomu Endo, Hideo Himeno, Kazuki Fukui, Shunichi Kobayashi, Makoto Shimizu, Yuji Iwasawa, Yukiko Morita, Atsushi Wada, Tomohiko Shigemasa, Yasuyuki Mochida, Tomoaki Shimizu, Reimin Sawada, Kazuaki Uchino, Satoshi Umemura, Kazuo Kimura

    Atherosclerosis   224 ( 2 )   454 - 456   2012.10

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    DOI： 10.1016/j.atherosclerosis.2012.07.036

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  • An Early and Simple Predictor of Severe Left Main and/or Three-Vessel Disease in Patients With Non–ST-Segment Elevation Acute Coronary Syndrome Reviewed

    Masami Kosuge, Toshiaki Ebina, Kiyoshi Hibi, Satoshi Morita, Mitsuaki Endo, Nobuhiki Maejima, Noriaki Iwahashi, Kozo Okada, Toshiyuki Ishikawa, Satoshi Umemura, Kazuo Kimura

    The American Journal of Cardiology   107 ( 4 )   495 - 500   2011.2

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    DOI： 10.1016/j.amjcard.2010.10.005

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  • Clinical Usefulness of Additional Treatment With Ezetimibe in Patients With Coronary Artery Disease on Statin Therapy Reviewed

    Kozo Okada, Kazuo Kimura, Noriaki Iwahashi, Tsutomu Endo, Hideo Himeno, Kazuki Fukui, Shunichi Kobayashi, Makoto Shimizu, Yuji Iwasawa, Yukiko Morita, Atsushi Wada, Tomohiko Shigemasa, Yasuyuki Mochida, Tomoaki Shimizu, Reimin Sawada, Kazuaki Uchino, Satoshi Umemura

    Circulation Journal   75 ( 10 )   2496 - 2504   2011

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    DOI： 10.1253/circj.cj-11-0391

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    Other Link： http://search.jamas.or.jp/link/ui/2012104027

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Books

  • 1. 非侵襲的検査 (7) 心臓CT

    加藤真吾, 関川善二郎, 岡田興造, 日比潔, 宇都宮大輔

    日本臨牀 81 (増刊号8)  2023.4 

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  • 2. 侵襲的検査 (4) 血管内超音波

    岡田興造, 日比潔

    日本臨牀 81 (増刊号8)  2023.4 

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  • Vital sensing devices in cardiovascular care

    Kozo Okada（ Role： Sole author）

    2022.10 

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  • 新PCI・カテーテル室のピンチからの脱出法 －達人が教える119のテクニック－「IX イメージングモダリティも上手に使える！ OCT b. OCTガイド活用：3Dイメージの使い道」

    岡田興造, 日比潔（ Role： Joint author）

    株式会社 南江堂  2021.9 

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  • 改訂第2版 PCIで使い倒すIVUS徹底活用術「側枝閉塞の予測と側枝保護のためのテクニック」

    岡田興造, 日比潔（ Role： Joint author）

    メジカルビュー社  2020.11 

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  • 【冠動脈インターベンションの現状と未来】IVUS/FFR/iFR

    Kozo Okada, Kiyoshi Hibi（ Role： Joint author）

    2020.2 

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  • Textbook of Catheter-Based Cardiovascular Interventions

    Kozo Okada, Peter J. Fitzgerald, Yasuhiro Honda（ Role： Joint authorIntravascular Ultrasound）

    Springer  2018 

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  • The role of intravascular ultrasound in percutaneous coronary intervention, Oxford Textbook of Interventional Cardiology

    Kozo Okada, Yasuhiro Honda, Peter J. Fitzgerald（ Role： Joint authorThe role of intravascular ultrasound in percutaneous coronary intervention）

    Oxford University Press  2018 

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  • High-Difinition IVUS (HD-IVUS)に期待するもの

    Kozo Okada, Yasuhiro Honda, Kiyoshi Hibi（ Role： Sole authorShinzo Vol 47, No 7）

    2015 

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  • 近赤外分光法 NIRS)を用いたプラーク評価

    Kozo OkadaYasuhiro Honda（ Role： Sole author循環器内科 76 (6) : 579-584）

    2014 

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  • 急性冠症候群 (Special Feature 先読みフローチャートで分かる イラスト&ビジュアルで循環器系救急に強くなる)

    岡田興造, 木村一雄

    Emergency care = エマージェンシー・ケア : 日本救急看護学会準機関誌  2012 

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MISC

  • 12誘導心電図画像のAI分析によるST上昇型心筋梗塞診断

    岡田興造, 濱上知樹, 後藤貴文, 神馬奈津子, 郷原正臣, 松下絢介, 小菅雅美, 海老名俊明, 菅野晃靖, 日比潔

    日本心臓病学会学術集会(Web)   72nd   2024

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  • Relationship between Microbiota-derived Trimethylamine N-oxide Levels and Long-term Prognosis after Guideline-based Secondary Prevention Therapy in Patients with Acute Myocardial Infarction(タイトル和訳中)

    中橋 秀文, 松澤 泰志, 岩橋 徳明, 岡田 興造, 木村 裕一郎, 南本 祐吾, 郷原 正臣, 菊地 進之介, 小菅 雅美, 木村 一雄, 田村 功一, 日比 潔

    日本循環器学会学術集会抄録集   87回   OJ02 - 2   2023.3

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  • Angle between Aortic Annulus and Myocardium in LVOT and Artioventricular Block in Patients with Aortic Stenosis Undergoing TAVI(和訳中)

    Kikuchi Shinnosuke, Hibi Kiyoshi, Minamimoto Yugo, Cho Tomoki, Terasaka Kengo, Okada Kozo, Matsuzawa Yasushi, Iwahashi Noriaki, Kosuge Masami, Ebina Toshiaki, Uchida Keiji, Tamura Kouichi, Kimura Kazuo

    日本循環器学会学術集会抄録集   86回   MPE08 - 9   2022.3

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  • 男性の急性心筋梗塞患者の心血管イベントに対し腸内細菌種のFirmicutesとBacteroidetesの比率が及ぼす影響(Impact of Firmicutes to Bacteroidetes Ratio on the Cardiovascular Events in Male Patients with Acute Myocardial Infarction)

    中橋 秀文, 松澤 泰志, 日比 潔, 岩橋 徳明, 岡田 興造, 木村 裕一郎, 南本 祐吾, 荻野 尭, 佐藤 亮佑, 菊地 進之介, 小菅 雅美, 田村 功一, 木村 一雄

    日本循環器学会学術集会抄録集   86回   PJ15 - 4   2022.3

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  • IMPACT OF EVOLOCUMAB ON PERIPROCEDURAL MICROVASCULAR DAMAGE IN PATIENTS UNDERGOING PERCUTANEOUS CORONARY INTERVENTION: THE EVOCATION TRIAL

    Masaharu Ishihara, Hibi Kiyoshi, Okada Kozo, Satoru Suwa, Wataru Shimizu, Hitoshi Takano, Kenshi Fujii, Yasuo Okumura, Toshiaki Mano, Kenichi Tsujita, Masataka Igeta, Shinichiro Suna, Masanori Asakura

    JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY   79 ( 9 )   1052 - 1052   2022.3

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  • Ratio of Left Ventricular Outflow Tract Area and Aortic Annulus Area Predicts Atrioventricular Block in Transcatheter Aortic Valve Implantation(和訳中)

    Kikuchi Shinnosuke, Hibi Kiyoshi, Minamimoto Yugo, Cho Tomoki, Terasaka Kengo, Okada Kozo, Matsuzawa Yasushi, Iwahashi Noriaki, Kosuge Masami, Ebina Toshiaki, Uchida Keiji, Tamura Kouichi, Kimura Kazuo

    日本循環器学会学術集会抄録集   86回   MPE08 - 6   2022.3

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  • The Index of Microcirculatory Resistance to Predict Subsequent Acute Cellular Rejection and Cardiac Events After Heart Transplantation

    Jung-Min Ahn, Frederik Zimmermann, Lars L. Gullestad, Oskar Angeras, Kristjan Karason, Kristoffer Russell, Ketil Lunde, Kozo Okada, Helen Luikart, Kiran K. Khush, Yasuhiro Honda

    CIRCULATION   144   2021.11

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  • 心機能および大動脈弁閉鎖不全症は重症大動脈弁狭窄症患者における経カテーテル大動脈弁置換術後の左室リバースリモデリングを予測する(Cardiac Function and Aortic Regurgitation Predict Left Ventricular Reverse-Remodeling after Transcatheter Aortic Valve Replacement in Patients with Severe Aortic Stenosis)

    Minamimoto Yugo, Hibi Kiyoshi, Choh Tomoki, Iwahashi Noriaki, Kikuchi Shinnosuke, Kirigaya Jin, Akiyama Eiichi, Okada Kozo, Matsuzawa Yasushi, Maejima Nobuhiko, Kosuge Masami, Ebina Toshiaki, Uchida Keiji, Tamura Kouichi, Kimura Kazuo

    日本循環器学会学術集会抄録集   85回   OE136 - 6   2021.3

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  • ST上昇型心筋梗塞に対する初回経皮的冠動脈インターベンション時の血小板機能に対するプラスグレル塩酸塩口腔内崩壊錠の負荷効果(Loading Effect of Prasugrel Orally Disintegrating Tablet on Platelet Function during Primary Percutaneous Coronary Intervention in ST-segment Elevation Myocardial Infarction)

    Kikuchi Shinnosuke, Tsukahara Kengo, Hibi Kiyoshi, Nakahashi Hidefumi, Minamimoto Yugo, Kimura Yuichiro, Akiyama Eiichi, Okada Kozo, Matsuzawa Yasushi, Maejima Nobuhiko, Iwahashi Noriaki, Kosuge Masami, Ebina Toshiaki, Tamura Kouichi, Kimura Kazuo

    日本循環器学会学術集会抄録集   85回   OE011 - 6   2021.3

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  • Feasibility of IVUS-Derived FFR as a Novel Technique to Estimate Functional Severity of Coronary Stenosis: Systematic Evaluation of Optimal Major Side Branch Definition to Determine the Reference Site for Automated FFR Calculation

    Kuninobu Kashiyama, Shinjo Sonoda, Kozo Okada, Kensuke Matsushita, Kiyoshi Hibi, M. Brooke Hollak, Paul G. Yock, Alan Young, Peter Fitzgerald, Yasuhiro Honda

    CIRCULATION   142   2020.11

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  • A First-in-Human Study of the Second-Generation, Thin-Strut, Everolimus- Eluting Bioresorbable Scaffold: Final IVUS and OCT Results From the FAST Clinical Trial

    Takeshi Nishi, Ryo Kameda, Kozo Okada, Masayasu Ikutomi, M. Brooke Hollak, Paul Yock, Jeffrey Popma, Sujith Seneviratne, Darren Walters, Robert Whitbourn, Jim Stewart, Seif El-Jack, Dominic Allocco, Ian Meredith, Peter J. Fitzgerald, Yasuhiro Honda

    JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY   76 ( 17 )   B117 - B118   2020.10

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  • Intravascular Ultrasound Radiofrequency Signal Analysis for Simultaneous Assessment of Functional Significance and Structural Abnormality of Intermediate Coronary Artery Lesions

    Kuninobu Kashiyama, Kozo Okada, Kensuke Matsushita, Kiyoshi Hibi, M. Brooke Hollak, Paul Yock, Alan C. Yeung, Peter J. Fitzgerald, Yasuhiro Honda

    JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY   76 ( 17 )   B123 - B124   2020.10

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  • FEASIBILITY OF IVUS-DERIVED FFR AS A NOVEL TECHNIQUE TO ESTIMATE FUNCTIONAL SEVERITY OF CORONARY STENOSIS: SYSTEMATIC EVALUATION OF THE METHODS TO DETERMINE THE REFERENCE LUMEN AREA FOR AUTOMATED FFR CALCULATION

    Kuninobu Kashiyama, Shinjo Sonoda, Kozo Okada, Kensuke Matsushita, Kiyoshi Hibi, Brooke Hollak, Paul G. Yock, Alan Yeung, Peter Fitzgerald, Yasuhiro Honda

    JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY   75 ( 11 )   1387 - 1387   2020.3

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  • 二次予防にICD移植を受けた冠血管攣縮性狭心症症例の臨床的特徴 器質的冠動脈狭窄症例との比較

    荻野 尭, 木村 一雄, 日比 潔, 岩橋 徳明, 松澤 泰志, 前島 信彦, 岡田 興造, 木村 裕一郎, 秋山 英一, 南本 祐吾, 佐藤 亮祐, 中橋 秀文, 桐ヶ谷 仁, 桐ヶ谷 英邦, 堤 勝彦

    日本冠疾患学会誌   ( Suppl.2019 )   159 - 159   2019.12

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  • 透析患者におけるQFRを用いた機能的虚血評価の有効性に関する研究

    桐ヶ谷 英邦, 岡田 興造, 日比 潔, 前島 信彦, 岩橋 徳明, 小菅 雅美, 海老名 俊明, 田村 功一, 木村 一雄

    日本冠疾患学会誌   ( Suppl.2019 )   158 - 158   2019.12

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  • Impact of Peri-scaffold Plaque Burden on Long-term Arterial Response and Target Lesion Failure Following Absorb Bioresorbable Scaffold Implantation

    Takeshi Nishi, Kozo Okada, Hideki Kitahara, Ryo Kameda, Masayasu Ikutomi, Brooke Hollak, Paul G. Yock, Jeffrey J. Popma, Hajime Kusano, Wai-Fung Cheong, Krishna Sudhir, Peter Fitzgerald, Stephen G. Ellis, Dean J. Kereiakes, Gregg W. Stone, Yasuhiro Honda, Takeshi Kimura

    CIRCULATION   140   2019.11

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  • Three Dimensional Strain Imaging is Superior to Two Dimensional Strain Imaging to Predict Adverse Left Ventricular Remodeling and Short-Term Prognosis After ST-segment-Elevation Myocardial Infarction

    Noriaki Iwahashi, Jin Kirigaya, Kozo Okada, Eiichi Akiyama, Yasushi Matsuzawa, Nobuhiko Maejima, Kiyoshi Hibi, Masami Kosuge, Toshiaki Ebina, Kouichi Tamura, Kazuo Kimura

    CIRCULATION   140   2019.11

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  • The Impact of Arterial Stiffness Assessed by Cardio-ankle Vascular Index on Long-term Outcome in Patients With Acute Coronary Syndrome

    Jin Kirigaya, Noriaki Iwahashi, Masaomi Gohbara, Eiichi Akiyama, Kozo Okada, Yasushi Matsuzawa, Nobuhiko Maejima, Kiyoshi Hibi, Masami Kosuge, Toshiaki Ebina, Kouichi Tamura, Kazuo Kimura

    CIRCULATION   140   2019.11

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  • Impact of Calcified Plaque on Vascular Remodeling After Bioresorbable Vascular Scaffold Implantation; Insights From the ABSORB III and ABSORB Japan Trials

    Shinji Imura, Takeshi Nishi, Kozo Okada, Hideki Kitahara, Ryo Kameda, Masayasu Ikutomi, Brooke Hollak, Paul G. Yock, Jeffrey J. Popma, Hajime Kusano, Wai-Fung Cheong, Krishna Sudhir, Peter Fitzgerald, Stephen G. Ellis, Dean Kereiakes, Gregg W. Stone, Yasuhiro Honda, Takeshi Kimura

    CIRCULATION   140   2019.11

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  • Feasibility of IVUS-Derived FFR as a Novel Technique to Estimate Functional Severity of Coronary Stenosis: Systematic Evaluation of Thresholds to Determine Diseased Segment

    Kuninobu Kashiyama, Shinjo Sonoda, Kensuke Matsushita, Kozo Okada, Kiyoshi Hibi, Kazuo Kimura, Brooke Hollak, Alan C. Yeung, Paul G. Yock, Peter Fitzgerald, Yasuhiro Honda

    CIRCULATION   140   2019.11

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  • Clinical Impact of Glycemic Variability on Left Ventricular Dysfunction Ata Chronic Phase in Patients Witha First St-segment Elevation Myocardial Infarction

    Jin Kirigaya, Jin Kirigaya, Noriaki Iwahashi, Masaomi Gohbara, Eiichi Akiyama, Kozo Okada, Yasushi Matsuzawa, Nobuhiko Maejima, Kiyoshi Hibi, Masami Kosuge, Toshiaki Ebina, Kouichi Tamura, Kazuo Kimura

    CIRCULATION   140   2019.11

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  • Prognostic Value of Skeletal Muscle Loss With Abnormal Abdominal Fat Distribution in Patients With St-segment Elevation Myocardial Infarction

    Ryosuke Satou, Kozo Okada, Eiichi Akiyama, Yasushi Matsuzawa, Masaaki Konishi, Nobuhiko Maejima, Noriaki Iwahashi, Kiyoshi Hibi, Masami Kosuge, Kouichi Tamura, Toshiaki Ebina, Kazuo Kimura

    CIRCULATION   140   2019.11

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  • Glycemic Variability is a Strong Predictor in Patients With Impaired Glucose Tolerance After First Episode of Acute Coronary Syndrome

    Yohei Hanajima, Noriaki Iwahashi, Jin Kirigaya, Hironori Takahashi, Yugo Minamimoto, Eiichi Akiyama, Kozo Okada, Nobuhiko Maejima, Yasushi Matsuzawa, Kiyoshi Hibi, Masami Kosuge, Toshiaki Ebina, Kouichi Tamura, Kazuo Kimura

    CIRCULATION   140   2019.11

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  • 心破裂を来したたこつぼ症候群の1例

    水上 紗緒里, 桐ヶ谷 英邦, 松澤 泰志, 岩橋 徳明, 前島 信彦, 岡田 興造, 秋山 英一, 日比 潔, 小菅 雅美, 木村 一雄

    日本内科学会関東地方会   654回   33 - 33   2019.10

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  • Association Between Platelet Aggregability During Primary Percutaneous Coronary Intervention and Increased Leukocyte in Patients With ST-Segment Elevation Myocardial Infarction

    Shinnosuke Kikuchi, Kengo Tsukahara, Shinya Ichikawa, Eiichi Akiyama, Kozo Okada, Yasushi Matsuzawa, Nobuhiko Maejima, Noriaki Iwahashi, Kiyoshi Hibi, Masami Kosuge, Toshiaki Ebina, Kouichi Tamura, Kazuo Kimura

    JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY   74 ( 13 )   B160 - B160   2019.10

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    DOI： 10.1016/j.jacc.2019.08.215

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  • Impact of Early Intervention With Alogliptin on Coronary Plaque Regression in Patients with Acute Coronary Syndromes: A Prospective, Single-Center, Randomized Trial

    Shinnosuke Kikuchi, Kozo Okada, Kiyoshi Hibi, Naoki Nakayama, Eiichi Akiyama, Yasushi Matsuzawa, Nobuhiko Maejima, Noriaki Iwahashi, Masami Kosuge, Toshiaki Ebina, Kouichi Tamura, Kazuo Kimura

    JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY   74 ( 13 )   B818 - B818   2019.10

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    DOI： 10.1016/j.jacc.2019.08.984

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  • Feasibility of IVUS-Derived FFR as a Novel Technique to Estimate Functional Severity of Coronary Stenosis

    Kuninobu Kashiyama, Shinjo Sonoda, Kensuke Matsushita, Kozo Okada, Eiichi Akiyama, Yasushi Matsuzawa, Nobuhiko Maejima, Noriaki Iwahashi, Kengo Tsukahara, Masami Kosuge, Toshiaki Ebina, Kiyoshi Hibi, Kouichi Tamura, Kazuo Kimura, M. Brooke Hollak, Paul G. Yock, Alan C. Yeung, Yasuhiro Honda

    JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY   74 ( 13 )   B325 - B325   2019.10

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    DOI： 10.1016/j.jacc.2019.08.407

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  • Impact of Myocardial Bridging on Long-Term Outcomes After Heart Transplantation: Risk Stratification With IVUS-Determined Anatomical Properties

    Kozo Okada, Takeshi Nishi, Shigemitsu Tanaka, Helen Luikart, Paul G. Yock, Alan C. Yeung, Kiyoshi Hibi, Kazuo Kimura, Ingela Schnittger, Kiran Khush, William Fearon, Yasuhiro Honda

    JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY   74 ( 13 )   B342 - B342   2019.10

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    DOI： 10.1016/j.jacc.2019.08.427

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  • The ABSORB III and ABSORB Japan Trials: Final Intravascular Ultrasound Results

    Yasuhiro Honda, Kozo Okada, Takeshi Nishi, Hideki Kitahara, Masayasu Ikutomi, M. Brooke Hollak, Paul G. Yock, Jeffrey Popma, Hajime Kusano, Wai-Fung Cheong, Krishna Sudhir, Stephen Ellis, Dean Kereiakes, Gregg Stone, Takeshi Kimura

    JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY   74 ( 13 )   B172 - B172   2019.10

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    DOI： 10.1016/j.jacc.2019.08.229

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  • Quantitative Flow Ratio for Assessment of Nonculprit Coronary Lesions in Patients With ST-Segment Elevation Myocardial Infarction

    Hidekuni Kirigaya, Kozo Okada, Kiyoshi Hibi, Eiichi Akiyama, Yasushi Matsuzawa, Noriaki Iwahashi, Nobuhiko Maejima, Masami Kosuge, Kazuo Kimura

    JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY   74 ( 13 )   B323 - B323   2019.10

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    DOI： 10.1016/j.jacc.2019.08.405

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  • Intravascular Ultrasound Predictors of Long-Term Outcomes Following ABSORB Bioresorbable Scaffold Implantation: A Pooled Analysis of the ABSORB III and ABSORB Japan Trials

    Takeshi Nishi, Kozo Okada, Hideki Kitahara, Masayasu Ikutomi, M. Brooke Hollak, Paul G. Yock, Jeffrey Popma, Hajime Kusano, Wai-Fung Cheong, Krishna Sudhir, Stephen Ellis, Dean Kereiakes, Gregg Stone, Yasuhiro Honda, Takeshi Kimura

    JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY   74 ( 13 )   B177 - B177   2019.10

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    DOI： 10.1016/j.jacc.2019.08.235

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  • 耐糖能障害を有する急性冠症候群における持続血糖モニタリングシステムにて計測した血糖変動と予後の検討

    花島 陽平, 高橋 広軌, 岩橋 徳明, 桐ヶ谷 仁, 秋山 英一, 木村 裕一郎, 岡田 興造, 松澤 泰志, 前島 信彦, 小菅 雅美, 日比 潔, 海老名 俊明, 田村 功一, 木村 一雄

    日本心臓病学会学術集会抄録   67回   O - 377   2019.9

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  • 透析患者における体液シフト 心不全患者での考察

    小西 正紹, 秋山 英一, 松澤 泰志, 佐藤 亮佑, 岡田 興造, 岩橋 徳明, 日比 潔, 海老名 俊明, 小菅 雅美, 前島 信彦, 田村 功一, 木村 一雄

    日本心臓病学会学術集会抄録   67回   SS - 4   2019.9

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  • 高齢者冠動脈疾患と多臓器連関 冠動脈疾患の各ステージにおける心・骨格筋・脂肪関連

    佐藤 亮佑, 小西 正紹, 秋山 英一, 松澤 泰志, 岡田 興造, 前島 信彦, 岩橋 徳明, 日比 潔, 小菅 雅美, 海老名 俊明, 田村 功一, 木村 一雄

    日本心臓病学会学術集会抄録   67回   S15 - 2   2019.9

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  • Impact of myocardial bridging on long-term outcomes after heart transplantation: risk stratification with IVUS-determined anatomical properties

    Okada K, Nishi T, Tanaka S, Luikart H, Yock PG, Yeung AC, Fitzgerald PJ, Schnittger I, Khush KK, Fearon WF, Honda Y

    2019.9

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  • ST上昇型急性心筋梗塞患者における体組成の予後への影響

    佐藤 亮佑, 秋山 英一, 松澤 泰志, 小西 正紹, 木村 裕一郎, 岡田 興造, 前島 信彦, 岩橋 徳明, 日比 潔, 小菅 雅美, 海老名 俊明, 田村 功一, 木村 一雄

    日本心臓病学会学術集会抄録   67回   O - 357   2019.9

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  • ST上昇型心筋梗塞患者におけるサルコペニアの要素と内皮機能障害との関係(Relationship between Components of Sarcopenia and Endothelial Dysfunction in Patients with ST-segment Elevation Myocardial Infarction)

    佐藤 亮佑, 松澤 泰志, 秋山 英一, 小西 正紹, 中橋 秀文, 木村 裕一郎, 岡田 興造, 前島 信彦, 岩橋 徳明, 小菅 雅美, 海老名 俊明, 日比 潔, 田村 功一, 木村 一雄

    日本循環器学会学術集会抄録集   83回   PJ047 - 6   2019.3

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  • A FIRST-IN-HUMAN STUDY OF THE SECOND-GENERATION, THIN-STRUT, EVEROLIMUS-ELUTING BIORESORBABLE SCAFFOLD: 6-MONTH IVUS AND OCT RESULTS FROM THE FAST CLINICAL TRIAL

    Ryo Kameda, Kozo Okada, Masayasu Ikutomi, M. Brooke Hollak, Paul Yock, Jeffrey Popma, Sujith Seneviratne, Andrejs Erglis, Darren Walters, Robert Whitbourn, Jamie Layland, Jim Stewart, Seif El-Jack, Thomas Christen, Ian Meredith, Peter Fitzgerald, Yasuhiro Honda

    JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY   73 ( 9 )   1111 - 1111   2019.3

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    DOI： 10.1016/S0735-1097(19)31718-8

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  • ST上昇型心筋梗塞患者の上肢および下肢における骨格筋量の予後に対する作用(Prognostic Effect of Skeletal Muscle Mass in Upper and Lower Extremities in Patients with ST-segment Elevation Myocardial Infarction)

    佐藤 亮佑, 秋山 英一, 小西 正紹, 松澤 泰志, 木村 裕一郎, 岡田 興造, 前島 信彦, 岩橋 徳明, 小菅 雅美, 海老名 俊明, 日比 潔, 田村 功一, 木村 一雄

    日本循環器学会学術集会抄録集   83回   OJ15 - 7   2019.3

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  • 初回ST部分上昇型心筋梗塞の患者における入院6時間後の高血糖は梗塞サイズを予測する(Hyperglycemia at 6 Hours can Predict Infarct Size in Patients with a First-time ST Elevation Acute Myocardial Infarction)

    堀井 睦夫, 岩橋 徳明, 桐ヶ谷 仁, 高橋 広軌, 中山 尚貴, 秋山 英一, 木村 裕一郎, 岡田 興造, 松澤 泰志, 小西 正紹, 前島 信彦, 小菅 雅美, 日比 潔, 海老名 俊明, 田村 功一, 木村 一雄

    日本循環器学会学術集会抄録集   83回   PJ002 - 5   2019.3

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  • PERIARTERIAL NEOVASCULARIZATION AND ATTENUATED-SIGNAL PLAQUE PREDICT LONG-TERM MORTALITY AFTER HEART TRANSPLANTATION: RISK STRATIFICATION WITH IVUS-DETERMINED CORONARY INFLAMMATORY FINDINGS

    Kuninobu Kashiyama, Kozo Okada, Hideki Kitahara, Ryo Kameda, M. Brooke Hollak, Helen Luikart, Paul Yock, Alan Yeung, Peter Fitzgerald, Kiran Khush, William Fearon, Yasuhiro Honda

    JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY   73 ( 9 )   1428 - 1428   2019.3

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    DOI： 10.1016/S0735-1097(19)32034-0

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  • INTRAVASCULAR ULTRASOUND PREDICTORS OF 4-YEAR CLINICAL OUTCOMES FOLLOWING ABSORB BIORESORBABLE SCAFFOLD IMPLANTATION: INSIGHTS FROM THE ABSORB JAPAN TRIAL

    Takeshi Nishi, Kozo Okada, Hideki Kitahara, Ryo Kameda, Masayasu Ikutomi, Brooke Hollak, Paul Yock, Jeffrey Popma, Hajime Kusano, Wai-Fung Cheong, Krishnankutty Sudhir, Peter Fitzgerald, Yasuhiro Honda, Takeshi Kimura

    JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY   73 ( 9 )   1305 - 1305   2019.3

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    DOI： 10.1016/S0735-1097(19)31912-6

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  • 急性冠症候群後の心血管イベントを予測する心臓足首血管指数とGRACEリスクスコアの併用評価の有用性(Usefulness of Combined Assessments of Cardioankle Vascular Index and GRACE Risk Score for Predicting Cardiovascular Events after Acute Coronary Syndrome)

    桐ヶ谷 仁, 岩橋 徳明, 岡田 興造, 松澤 泰志, 小西 正紹, 前島 信彦, 小菅 雅美, 日比 潔, 海老名 俊明, 田村 功一, 木村 一雄

    日本循環器学会学術集会抄録集   83回   PJ086 - 5   2019.3

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  • ST上昇型心筋梗塞患者における睡眠呼吸障害と造影剤誘発性腎障害との関連(Association between Sleep-disordered Breathing and Contrast-Induced Nephropathy in Patients with ST-Segment Elevation Myocardial Infarction)

    桐ヶ谷 仁, 岩橋 徳明, 岡田 興造, 松澤 泰志, 小西 正紹, 前島 信彦, 小菅 雅美, 日比 潔, 海老名 俊明, 田村 功一, 木村 一雄

    日本循環器学会学術集会抄録集   83回   PJ039 - 7   2019.3

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  • 内皮機能および心血管リスクの線形用量反応関係(A Linear dose-Response Relationship between Endothelial Function and Cardiovascular Risk)

    松澤 泰志, 杉山 正悟, 小西 正紹, 秋山 英一, 佐藤 亮佑, 中橋 秀文, 日比 潔, 岩橋 徳明, 前島 信彦, 岡田 興造, 小菅 雅美, 田村 功一, 木村 一雄

    日本循環器学会学術集会抄録集   83回   PJ045 - 6   2019.3

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  • 持続的血糖モニタリングシステムで検出された急性期低血糖はSTEMI患者における不良な予後を予測する(Hypoglycemia in Acute Phase Detected by Contentious Glucose Monitoring System can Predict Poor Prognosis in Patients with STEMI)

    高橋 広軌, 岩橋 徳明, 桐ヶ谷 仁, 南本 祐吾, 秋山 英一, 岡田 興造, 松澤 泰志, 小西 正紹, 前島 信彦, 日比 潔, 小菅 雅美, 海老名 俊明, 田村 功一, 木村 一雄

    日本循環器学会学術集会抄録集   83回   PJ018 - 3   2019.3

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  • LVOT-VTI×平均BPは急性心房細動に対する血行動態の状態を評価するための有用な心エコー指標である(LVOT-VTI×Mean BP is The Useful Echocardiographic Index to Evaluate the Hemodynamic Status for Rapid Atrial Fibrillation)

    岩橋 徳明, 桐ヶ谷 仁, 高橋 広軌, 堀井 睦夫, 木村 裕一郎, 秋山 英一, 岡田 興造, 松澤 泰志, 小西 正紹, 前島 信彦, 日比 潔, 小菅 雅美, 海老名 俊明, 田村 功一, 木村 一雄

    日本循環器学会学術集会抄録集   83回   PJ021 - 3   2019.3

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  • Urgent Control of Rapid Atrial Fibrillation Using Landiolol in Patients With Heart Failure and Severely Reduced Ejection Fraction in Acute Decompensated Heart Failure

    Noriaki Iwahashi, Hironori Takahashi, Eiichi Akiyama, Kozo Okada, Yasushi Matsuzawa, Masaaki Konishi, Nobuhiko Maejima, Kiyoshi Hibi, Masami Kosuge, Toshiaki Ebina, Koichi Tamura, Kazuo Kimura

    CIRCULATION   138   2018.11

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  • Glycemic Variability Immediately After Hospitalization Can Predict Left Ventricle Remodeling in ST-Segment Elevation Myocardial Infarction Patients

    Takahashi Hironori, Noriaki Iwahashi, Kozo Okada, Yasushi Matsuzawa, Masaaki Konishi, Nobuhiko Maejima, Kiyoshi Hibi, Masami Kosuge, Toshiaki Ebina, Kouichi Tamura, Kazuo Kimura

    CIRCULATION   138   2018.11

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  • Glycemic Variability Determined With a Continuous Glucose Monitoring System Can Predict Prognosis After Acute Coronary Syndrome

    Hironori Takahashi, Noriaki Hironori, Jin Kirigaya, Yugo Minamimoto, Yasushi Matsuzawa, Kozo Okada, Masaaki Konishi, Nobuhiko Maejima, Kiyoshi Hibi, Masami Kosuge, Toshiaki Ebina, Kouichi Tamura, Kazuo Kimura

    CIRCULATION   138   2018.11

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  • Impact of Myocardial Bridging on Long-Term Mortality After Heart Transplantation: Risk Stratification With Ivus-Determined Cardiac Allograft Vasculopathy

    Ryo Kameda, Kozo Okada, Shigemitsu Tanaka, Helen Luikart, Paul G. Yock, Alan C. Yeung, Ingela Schnittger, Peter J. Fitzgerald, Kiran K. Khush, William F. Fearon, Yasuhiro Honda

    CIRCULATION   138   2018.11

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  • Global Strain Estimated by 3D Speckle Tracking Combined With E/E' is the Strongest Predictor in Patients With STEMI

    Noriaki Iwahashi, Hironori Takahashi, Eiichi Akiyama, Kozo Okada, Yasushi Matsuzawa, Masaaki Konishi, Nobuhiko Maejima, Kiyoshi Hibi, Masami Kosuge, Toshiaki Ebina, Koichi Tamura, Kazuo Kimura

    CIRCULATION   138   2018.11

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  • Clinical predictors of discordance between instantaneous wavefree ratio and fractional flow reserve

    Hidekuni Kirigaya, Kensuke Matsushita, Kozo Okada, Noriaki Iwahashi, Nobuhiko Maejima, Toshiaki Ebina, Kouichi Tamura, Kiyoshi Hibi, Kazuo Kimura

    JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY   72 ( 13 )   B65 - B65   2018.9

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    DOI： 10.1016/j.jacc.2018.08.1261

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  • Attenuated-Signal Plaque and Long-Term Vessel Response after Bioresorbable Scaffold Implantation: IVUS Insights from the ABSORB JAPAN Trial

    Kozo Okada, Yasuhiro Honda, Hideki Kitahara, Ryo Kameda, M. Brooke Hollak, Paul G. Yock, Hajime Kusano, Wai-Fung Cheong, Krishna Sudhir, Takeshi Kimura

    JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY   72 ( 13 )   B68 - B68   2018.9

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    DOI： 10.1016/j.jacc.2018.08.1270

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  • Long-Term Vascular Response to Bioresorbable Scaffolds Versus Metallic Stents in Coronary Lesions with Myocardial Bridging: A Potential Benefit of Vascular Restoration Under Dynamic Compression Force

    Ryo Kameda, Kozo Okada, Hideki Kitahara, M. Brooke Hollak, Paul G. Yock, Jeffrey Popma, Hajime Kusano, Wai-Fung Cheong, Krishna Sudhir, Yasuhiro Honda, Takeshi Kimura

    JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY   72 ( 13 )   B128 - B128   2018.9

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    DOI： 10.1016/j.jacc.2018.08.1452

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  • Relationship between enzymatic infarct size and total platelet aggregability during primary percutaneous coronary intervention in patients with ST-elevation myocardial infarction

    Shinnosuke Kikuchi, Kengo Tsukahara, Shinya Ichikawa, Yugo Minamimoto, Kozo Okada, Yasushi Matsuzawa, Masaaki Konishi, Nobuhiko Maejima, Noriaki Iwahashi, Kiyoshi Hibi, Masami Kosuge, Toshiaki Ebina, Kouichi Tamura, Kazuo Kimura

    JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY   72 ( 13 )   B313 - B313   2018.9

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    DOI： 10.1016/j.jacc.2018.08.2016

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  • 不安定狭心症を契機に高安動脈炎の診断となった高齢女性の1例

    菊地 進之介, 岡田 興造, 木村 裕一郎, 松澤 泰志, 小西 正紹, 前島 信彦, 岩橋 徳明, 日比 潔, 小菅 雅美, 海老名 俊明, 田村 功一, 木村 一雄

    日本心臓病学会学術集会抄録   66回   EP - 067   2018.9

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  • Low skeletal mass is associated with poor cardiovascular outcome in patients after ST-segment elevation myocardial infarction

    Satou R, Matsuzawa Y, Konishi M, Kawashima C, Okada K, Maejima N, Iwahashi N, Hibi K, Kosuge M, Ebina T, Tamura K, Kimura K

    2018.8

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  • 術後慢性期に血栓弁となったTAVIの一例

    桐ヶ谷 仁, 岩橋 徳明, 松澤 泰志, 岡田 興造, 小西 正昭, 前島 信彦, 小菅 雅美, 日比 潔, 木村 一雄, 田村 功一

    超音波医学   45 ( Suppl. )   S622 - S622   2018.4

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  • Bioresorbable Scaffold for Treatment of Coronary Artery Lesions: Final Intravascular Ultrasound Results from the ABSORB JAPAN Trial

    Okada K, Honda Y, Kitahara H, Ikutomi M, Kameda R, Hollak MB, Yock P, Kusano H, Cheong WF, Sudhir K, Fitzgerald PJ, Kimura T

    2018.3

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  • BIORESORBABLE SCAFFOLD FOR TREATMENT OF CORONARY ARTERY LESIONS: FINAL INTRAVASCULAR ULTRASOUND RESULTS FROM THE ABSORB JAPAN TRIAL

    Kozo Okada, Yasuhiro Honda, Hideki Kitahara, Masayasu Ikutomi, Ryo Kameda, M. Brooke Hollak, Paul Yock, Hajime Kusano, Wai-Fung Cheong, Krishnan Sudhir, Peter Fitzgerald, Takeshi Kimura

    JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY   71 ( 11 )   1020 - 1020   2018.3

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    DOI： 10.1016/S0735-1097(18)31561-4

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  • Association Between Scaffold Under-Expansion and Late Lumen Loss after Bioresorbable Scaffold Implantation: IVUS and Angiographic Insights from the ABSORB Japan Trial

    Kozo Okada, Yasuhiro Honda, Hideki Kitahara, M. Brooke Hollak, Paul G. Yock, Jeffrey J. Popma, Hajime Kusano, Wai-Fung Cheong, Krishna Sudhir, Peter J. Fitzgerald, Takeshi Kimura

    JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY   70 ( 18 )   B5 - B5   2017.10

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    DOI： 10.1016/j.jacc.2017.09.076

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  • Comparison of Bioresorbable Scaffold Measurements between Intravascular Ultrasound and Quantitative Coronary Angiography in the ABSORB Japan Trial

    Kozo Okada, Yasuhiro Honda, Hideki Kitahara, M. Brooke Hollak, Paul G. Yock, Jeffrey J. Popma, Hajime Kusano, Wai-Fung Cheong, Krishna Sudhir, Peter J. Fitzgerald, Takeshi Kimura

    JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY   70 ( 18 )   B57 - B58   2017.10

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    DOI： 10.1016/j.jacc.2017.09.190

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  • Impact of Underexpansion on IVUS-Derived Wall Shear Stress Patterns with Bioresorbable Scaffolds and Metallic DES: Insights from the ABSORB III Imaging Substudy

    Bill Gogas, Elizabeth Thompson, David Molony, Nikolaos Spilias, Kozo Okada, Yasuhiro Honda, Alessandro Veneziani, Don P. Giddens, Richard Rapoza, Jeffrey J. Popma, Gregg Stone

    JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY   70 ( 18 )   B187 - B187   2017.10

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    DOI： 10.1016/j.jacc.2017.09.563

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  • Bioresorbable Scaffold for the Treatment of Calcified Coronary Lesions: IVUS Insights from the ABSORB Japan Trial

    Kozo Okada, Yasuhiro Honda, Hideki Kitahara, M. Brooke Hollak, Paul G. Yock, Hajime Kusano, Wai-Fung Cheong, Krishna Sudhir, Peter J. Fitzgerald, Takeshi Kimura

    JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY   70 ( 18 )   B19 - B19   2017.10

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    DOI： 10.1016/j.jacc.2017.09.091

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  • Comparison of Bioresorbable Scaffold Measurements between Intravascular Ultrasound and Quantitative Coronary Angiography in the ABSORB Japan Trial

    Kozo Okada, Yasuhiro Honda, Hideki Kitahara, M. Brooke Hollak, Paul G. Yock, Jeffrey J. Popma, Hajime Kusano, Wai-Fung Cheong, Krishna Sudhir, Peter J. Fitzgerald, Takeshi Kimura

    JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY   70 ( 18 )   B57 - B58   2017.10

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    DOI： 10.1016/j.jacc.2017.09.190

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  • Bioresorbable Scaffold for the Treatment of Calcified Coronary Lesions: IVUS Insights from the ABSORB Japan Trial

    Kozo Okada, Yasuhiro Honda, Hideki Kitahara, M. Brooke Hollak, Paul G. Yock, Hajime Kusano, Wai-Fung Cheong, Krishna Sudhir, Peter J. Fitzgerald, Takeshi Kimura

    JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY   70 ( 18 )   B19 - B19   2017.10

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    DOI： 10.1016/j.jacc.2017.09.091

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  • Association Between Scaffold Under-Expansion and Late Lumen Loss after Bioresorbable Scaffold Implantation: IVUS and Angiographic Insights from the ABSORB Japan Trial

    Kozo Okada, Yasuhiro Honda, Hideki Kitahara, M. Brooke Hollak, Paul G. Yock, Jeffrey J. Popma, Hajime Kusano, Wai-Fung Cheong, Krishna Sudhir, Peter J. Fitzgerald, Takeshi Kimura

    JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY   70 ( 18 )   B5 - B5   2017.10

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    DOI： 10.1016/j.jacc.2017.09.076

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  • Differential Late Stent Enlargement and Vascular Response Following New-Generation Self-Expanding Stent Implantation in Tapered Peripheral Arteries: Insights from Serial Optical Coherence Tomography

    Masayasu Ikutomi, Kozo Okada, Kojiro Miki, Ryo Kameda, Fumiyuki Otsuka, Paul G. Yock, Peter J. Fitzgerald, Osami Kawarada, Yasuhiro Honda

    JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY   70 ( 18 )   B165 - B166   2017.10

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    DOI： 10.1016/j.jacc.2017.09.501

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  • Differential Late Stent Enlargement and Vascular Response Following New-Generation Self-Expanding Stent Implantation in Tapered Peripheral Arteries: Insights from Serial Optical Coherence Tomography

    Masayasu Ikutomi, Kozo Okada, Kojiro Miki, Ryo Kameda, Fumiyuki Otsuka, Paul G. Yock, Peter J. Fitzgerald, Osami Kawarada, Yasuhiro Honda

    JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY   70 ( 18 )   B165 - B166   2017.10

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    DOI： 10.1016/j.jacc.2017.09.501

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  • Attenuated-Signal Plaque and Long-Term Vessel Response After Bioresorbable Scaffold Implantation: IVUS Insights from the ABSORB JAPAN Trial

    Okada K, Honda Y, Kitahara H, Kameda R, Hollak MB, Yock PG, Kusano H, Cheong WF, Sudhir K, Kimura T

    2017.9

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  • Angiotensin-Converting Enzyme Inhibition Early After Heart Transplantation Reviewed

    William F. Fearon, Kozo Okada, Jon A. Kobashigawa, Yuhei Kobayashi, Helen Luikart, Sean Sana, Tiffany Daun, Steven A. Chmura, Seema Sinha, Garett Cohen, Yasuhiro Honda, Michael Pham, David B. Lewis, Daniel Bernstein, Alan C. Yeung, Hannah A. Valantine, Kiran Khush

    JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY   69 ( 23 )   2832 - 2841   2017.6

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  • PERI-STRUT LOW INTENSITY AREA PREDICTS NEOINTIMAL PROGRESSION ASSOCIATED WITH LATE ENLARGEMENT OF SELF-EXPANDING NITINOL STENTS IN SUPERFICIAL FEMORAL ARTERIES: AN OPTICAL COHERENCE TOMOGRAPHY STUDY

    Masayasu Ikutomi, Kozo Okada, Kojiro Miki, Ryo Kameda, Fumiyuki Otsuka, Paul Yock, Peter Fitzgerald, Osami Kawarada, Yasuhiro Honda

    JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY   69 ( 11 )   999 - 999   2017.3

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    DOI： 10.1016/S0735-1097(17)34388-7

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  • PERI-STRUT LOW INTENSITY AREA PREDICTS NEOINTIMAL PROGRESSION ASSOCIATED WITH LATE ENLARGEMENT OF SELF-EXPANDING NITINOL STENTS IN SUPERFICIAL FEMORAL ARTERIES: AN OPTICAL COHERENCE TOMOGRAPHY STUDY

    Masayasu Ikutomi, Kozo Okada, Kojiro Miki, Ryo Kameda, Fumiyuki Otsuka, Paul Yock, Peter Fitzgerald, Osami Kawarada, Yasuhiro Honda

    JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY   69 ( 11 )   999 - 999   2017.3

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    DOI： 10.1016/S0735-1097(17)34388-7

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  • Comparison between Instantaneous Wave-Free Ratio and Fractional Flow Reserve versus Morphometric Assessments by Intracoronary Imaging Devices

    Kensuke Matsushita, Kiyoshi Hibi, Kozo Okada, Yasushi Matsuzawa, Yuichiro Kimura, Nobuhiko Maejima, Noriaki Iwahashi, Anton Moritz, Toshiaki Ebina, Peter J. Fitzgerald, Yasuhiro Honda, Kazuo Kimura

    JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY   68 ( 18 )   B218 - B218   2016.11

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    DOI： 10.1016/j.jacc.2016.09.676

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  • Bioresorbable Vascular Scaffold for the Treatment of Tapered Coronary Lesions

    Kozo Okada, Hideki Kitahara, Paul Yock, Peter J. Fitzgerald, Takeshi Kimura, Yasuhiro Honda

    JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY   68 ( 18 )   B165 - B165   2016.11

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    DOI： 10.1016/j.jacc.2016.09.541

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  • Bioresorbable Vascular Scaffold for the Treatment of Tapered Coronary Lesions

    Kozo Okada, Hideki Kitahara, Paul Yock, Peter J. Fitzgerald, Takeshi Kimura, Yasuhiro Honda

    JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY   68 ( 18 )   B165 - B165   2016.11

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    DOI： 10.1016/j.jacc.2016.09.541

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  • Early Invasive Assessment of the Coronary Microcirculation Predicts Subsequent Acute Rejection After Heart Transplantation

    Kozo Okada, Yasuhiro Honda, Helen Luikart, Paul G. Yock, Peter J. Fitzgerald, Alan C. Yeung, Hannah A. Valantine, Kiran K. Khush, William F. Fearon

    CIRCULATION   134   2016.11

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  • Early Left Ventricular Dysfunction is Associated with Cardiac Allograft Vasculopathy and Late Mortality After Heart Transplantation

    Kozo Okada, Yasuhiro Honda, Helen Luikart, Paul G. Yock, Peter J. Fitzgerald, Alan C. Yeung, Hannah Valantine, Kiran Khush, William Fearon

    JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY   68 ( 18 )   B331 - B331   2016.11

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    DOI： 10.1016/j.jacc.2016.09.909

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  • Early Left Ventricular Dysfunction is Associated with Cardiac Allograft Vasculopathy and Late Mortality After Heart Transplantation

    Kozo Okada, Yasuhiro Honda, Helen Luikart, Paul G. Yock, Peter J. Fitzgerald, Alan C. Yeung, Hannah Valantine, Kiran Khush, William Fearon

    JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY   68 ( 18 )   B331 - B331   2016.11

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    DOI： 10.1016/j.jacc.2016.09.909

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  • Comparison between Instantaneous Wave-Free Ratio and Fractional Flow Reserve versus Morphometric Assessments by Intracoronary Imaging Devices

    Kensuke Matsushita, Kiyoshi Hibi, Kozo Okada, Yasushi Matsuzawa, Yuichiro Kimura, Nobuhiko Maejima, Noriaki Iwahashi, Anton Moritz, Toshiaki Ebina, Peter J. Fitzgerald, Yasuhiro Honda, Kazuo Kimura

    JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY   68 ( 18 )   B218 - B218   2016.11

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    DOI： 10.1016/j.jacc.2016.09.676

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  • EARLY CORONARY ENDOTHELIAL DYSFUNCTION PREDICTS ACCELERATED PLAQUE PROGRESSION 1 YEAR AFTER CARDIAC TRANSPLANTATION: SERIAL VOLUMETRIC EVALUATION BY INTRAVASCULAR ULTRASOUND

    Jang Hoon Lee, Kozo Okada, Kiran Khush, Yuhei Kobayashi, Seema Sinha, Helen Luikart, Hannah Valantine, Alan Yeung, Yasuhiro Honda, William Fearon

    JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY   67 ( 13 )   364 - 364   2016.4

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    DOI： 10.1016/S0735-1097(16)30365-5

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  • FRACTIONAL FLOW RESERVE IN PATIENTS WITH ANGINA IN THE ABSENCE OF OBSTRUCTIVE CORONARY ARTERY DISEASE: IS THERE SUCH A THING AS NORMAL CORONARY ARTERIES?

    Takumi Kimura, William Fearon, Yuhei Kobayashi, Kozo Okada, Kojiro Miki, Vedant Pargaonkar, Paul Yock, Peter Fitzgerald, Yasuhiro Honda, Alan Yeung, Jennifer Tremmel

    JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY   67 ( 13 )   375 - 375   2016.4

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    DOI： 10.1016/S0735-1097(16)30376-X

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  • ANGIOTENSIN-CONVERTING ENZYME INHIBITION EARLY AFTER CARDIAC TRANSPLANTATION: A MULTI-CENTER, RANDOMIZED, DOUBLE-BLIND TRIAL COMPARING RAMIPRIL VERSUS PLACEBO

    Yuhei Kobayashi, Kozo Okada, Kiran Khush, Sean Sana, Tiffany Daun, Seema Sinha, Garrett Cohen, Yasuhiro Honda, Helen Luikart, Hannah Valantine, Alan Yeung, Jon Kobashigawa, William Fearon

    JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY   67 ( 13 )   1445 - 1445   2016.4

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    DOI： 10.1016/S0735-1097(16)31446-2

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  • EARLY CORONARY ENDOTHELIAL DYSFUNCTION PREDICTS ACCELERATED PLAQUE PROGRESSION 1 YEAR AFTER CARDIAC TRANSPLANTATION: SERIAL VOLUMETRIC EVALUATION BY INTRAVASCULAR ULTRASOUND

    Jang Hoon Lee, Kozo Okada, Kiran Khush, Yuhei Kobayashi, Seema Sinha, Helen Luikart, Hannah Valantine, Alan Yeung, Yasuhiro Honda, William Fearon

    JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY   67 ( 13 )   364 - 364   2016.4

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    DOI： 10.1016/S0735-1097(16)30365-5

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  • FRACTIONAL FLOW RESERVE IN PATIENTS WITH ANGINA IN THE ABSENCE OF OBSTRUCTIVE CORONARY ARTERY DISEASE: IS THERE SUCH A THING AS NORMAL CORONARY ARTERIES?

    Takumi Kimura, William Fearon, Yuhei Kobayashi, Kozo Okada, Kojiro Miki, Vedant Pargaonkar, Paul Yock, Peter Fitzgerald, Yasuhiro Honda, Alan Yeung, Jennifer Tremmel

    JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY   67 ( 13 )   375 - 375   2016.4

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    DOI： 10.1016/S0735-1097(16)30376-X

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  • ANGIOTENSIN-CONVERTING ENZYME INHIBITION EARLY AFTER CARDIAC TRANSPLANTATION: A MULTI-CENTER, RANDOMIZED, DOUBLE-BLIND TRIAL COMPARING RAMIPRIL VERSUS PLACEBO

    Yuhei Kobayashi, Kozo Okada, Kiran Khush, Sean Sana, Tiffany Daun, Seema Sinha, Garrett Cohen, Yasuhiro Honda, Helen Luikart, Hannah Valantine, Alan Yeung, Jon Kobashigawa, William Fearon

    JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY   67 ( 13 )   1445 - 1445   2016.4

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    DOI： 10.1016/S0735-1097(16)31446-2

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  • IMPACT OF FINAL STENT DIMENSIONS ON ANGIOGRAPHIC RESTENOSIS FOLLOWING SELF-EXPANDING NITINOL STENT IMPLANTATION IN THE SUPERFICIAL FEMORAL ARTERY LESION

    Kojiro Miki, Kenichi Fujii, Takumi Kimura, Kozo Okada, Tohru Masuyama, Masaharu Ishihara, Peter Fitzgerald, Yasuhiro Honda

    JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY   67 ( 13 )   313 - 313   2016.4

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    DOI： 10.1016/S0735-1097(16)30314-X

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  • IMPACT OF FINAL STENT DIMENSIONS ON ANGIOGRAPHIC RESTENOSIS FOLLOWING SELF-EXPANDING NITINOL STENT IMPLANTATION IN THE SUPERFICIAL FEMORAL ARTERY LESION

    Kojiro Miki, Kenichi Fujii, Takumi Kimura, Kozo Okada, Tohru Masuyama, Masaharu Ishihara, Peter Fitzgerald, Yasuhiro Honda

    JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY   67 ( 13 )   313 - 313   2016.4

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    DOI： 10.1016/S0735-1097(16)30314-X

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  • ASSESSMENT OF BIORESORBABLE SCAFFOLD STRUTS WITH A NOVEL HIGH-DEFINITION 60MHZ IVUS IMAGING SYSTEM: COMPARISON WITH 40MHZ IVUS AND OPTICAL COHERENCE TOMOGRAPHY

    Kozo Okada, Kozo Okada, Hideki Kitahara, Yoshiaki Mitsutake, Takumi Kimura, Kojiro Miki, Fumiaki Ikeno, Paul Yock, Peter Fitzgerald, Yasuhiro Honda

    JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY   67 ( 13 )   255 - 255   2016.4

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    DOI： 10.1016/S0735-1097(16)30256-X

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  • ASSESSMENT OF BIORESORBABLE SCAFFOLD STRUTS WITH A NOVEL HIGH-DEFINITION 60MHZ IVUS IMAGING SYSTEM: COMPARISON WITH 40MHZ IVUS AND OPTICAL COHERENCE TOMOGRAPHY

    Kozo Okada, Kozo Okada, Hideki Kitahara, Yoshiaki Mitsutake, Takumi Kimura, Kojiro Miki, Fumiaki Ikeno, Paul Yock, Peter Fitzgerald, Yasuhiro Honda

    JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY   67 ( 13 )   255 - 255   2016.4

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    DOI： 10.1016/S0735-1097(16)30256-X

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  • IMPACT OF STENT DIAMETER ON STENT PATENCY AFTER SELF-EXPANDING PACLITAXEL-ELUTING STENT IMPLANTATION IN THE SUPERFICIAL FEMORAL ARTERY: AN INTERIM REPORT

    Kojiro Miki, Kenichi Fujii, Tetsuo Horimatsu, Takumi Kimura, Kozo Okada, Tohru Masuyama, Masaharu Ishihara, Peter Fitzgerald, Yasuhiro Honda

    JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY   67 ( 13 )   312 - 312   2016.4

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    DOI： 10.1016/S0735-1097(16)30313-8

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  • IMPACT OF STENT DIAMETER ON STENT PATENCY AFTER SELF-EXPANDING PACLITAXEL-ELUTING STENT IMPLANTATION IN THE SUPERFICIAL FEMORAL ARTERY: AN INTERIM REPORT

    Kojiro Miki, Kenichi Fujii, Tetsuo Horimatsu, Takumi Kimura, Kozo Okada, Tohru Masuyama, Masaharu Ishihara, Peter Fitzgerald, Yasuhiro Honda

    JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY   67 ( 13 )   312 - 312   2016.4

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    DOI： 10.1016/S0735-1097(16)30313-8

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  • BIORESORBABLE SCAFFOLD FOR THE TREATMENT OF LESIONS IN SMALL CORONARY ARTERIES: IVUS INSIGHTS FROM THE ABSORB JAPAN TRIAL

    Kozo Okada, Hideki Kitahara, Kyuhachi Otagiri, Shigemitsu Tanaka, Takumi Kimura, Paul Yock, Peter Fitzgerald, Takeshi Kimura, Yasuhiro Honda

    JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY   67 ( 13 )   368 - 368   2016.4

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    DOI： 10.1016/S0735-1097(16)30369-2

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  • BIORESORBABLE SCAFFOLD FOR THE TREATMENT OF LESIONS IN SMALL CORONARY ARTERIES: IVUS INSIGHTS FROM THE ABSORB JAPAN TRIAL

    Kozo Okada, Hideki Kitahara, Kyuhachi Otagiri, Shigemitsu Tanaka, Takumi Kimura, Paul Yock, Peter Fitzgerald, Takeshi Kimura, Yasuhiro Honda

    JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY   67 ( 13 )   368 - 368   2016.4

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    DOI： 10.1016/S0735-1097(16)30369-2

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  • ENDOTHELIUM DEPENDENT AND INDEPENDENT VASODILATOR RESPONSES AFTER HEART TRANSPLANTATION: GEOGRAPHIC DISTRIBUTION AND ASSOCIATION WITH PROGRESSION OF CARDIAC ALLOGRAFT VASCULOPATHY

    Kozo Okada, Takumi Kimura, Kojiro Miki, Paul Yock, Alan Yeung, Peter Fitzgerald, Helen Luikart, Kiran Khush, Yasuhiro Honda, William Fearon

    JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY   67 ( 13 )   254 - 254   2016.4

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    DOI： 10.1016/S0735-1097(16)30255-8

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  • ENDOTHELIUM DEPENDENT AND INDEPENDENT VASODILATOR RESPONSES AFTER HEART TRANSPLANTATION: GEOGRAPHIC DISTRIBUTION AND ASSOCIATION WITH PROGRESSION OF CARDIAC ALLOGRAFT VASCULOPATHY

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    JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY   67 ( 13 )   254 - 254   2016.4

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  • Ultrasound and Angiographic Predictors for 5-Year Target Lesion Revascularization After Second Generation Drug-Eluting Stent Implantation

    Hideki Kitahara, Kenji Sakamoto, Kozo Okada, Yuhei Kobayashi, Takumi Kimura, Paul G. Yock, Alan C. Yeung, Peter J. Fitzgerald, Yasuhiro Honda

    CIRCULATION   132   2015.11

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  • Ultrasound and Angiographic Predictors for 5-Year Target Lesion Revascularization After Second Generation Drug-Eluting Stent Implantation

    Hideki Kitahara, Kenji Sakamoto, Kozo Okada, Yuhei Kobayashi, Takumi Kimura, Paul G. Yock, Alan C. Yeung, Peter J. Fitzgerald, Yasuhiro Honda

    CIRCULATION   132   2015.11

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  • Head-to-Head Comparison of Two Commercially Available Automated Detection Algorithms for Lumen Contour in Optical Coherence Tomography Analysis

    Kyuhachi Otagiri, Hideki Kitahara, Shigemitsu Tanaka, Kozo Okada, Yuhei Kobayashi, Takashi Miura, Soichiro Ebisawa, Yusuke Miyashita, Hiroshi Kitabayashi, Paul Yock, Peter J. Fitzgerald, Uichi Ikeda, Yasuhiro Honda

    JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY   66 ( 15 )   B136 - B136   2015.10

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    DOI： 10.1016/j.jacc.2015.08.356

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  • Association between Increased Number of Septal Branches within the Myocardial Bridge and Abnormal Diastolic-Fractional Flow Reserve

    Takumi Kimura, Shigemitsu Tanaka, Kozo Okada, Hideki Kitahara, Yuhei Kobayashi, Yukari Kobayashi, Vedant S. Pargaonkar, Paul Yock, Peter J. Fitzgerald, Yasuhiro Honda, Ian S. Rogers, Jennifer A. Tremmel, Ingela Schnittger

    JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY   66 ( 15 )   B139 - B140   2015.10

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    DOI： 10.1016/j.jacc.2015.08.964

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  • Impact of Stent Size Selection on Acute and Long-Term Outcomes after Drug-Eluting Stent Implantation in De Novo Coronary Lesions

    Hideki Kitahara, Kozo Okada, Yuhei Kobayashi, Takumi Kimura, Paul Yock, Peter J. Fitzgerald, Yasuhiro Honda

    JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY   66 ( 15 )   B225 - B225   2015.10

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    DOI： 10.1016/j.jacc.2015.08.1025

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  • Factors Affecting Quantitative Stent Assessment by Optical Frequency Domain Imaging: In Vivo Direct Comparison with Intravascular Ultrasound

    Yuhei Kobayashi, Hideki Kitahara, Shigemitsu Tanaka, Kozo Okada, Takumi Kimura, Fumiaki Ikeno, Paul Yock, Peter J. Fitzgerald, Yasuhiro Honda

    JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY   66 ( 15 )   B134 - B135   2015.10

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    DOI： 10.1016/j.jacc.2015.08.352

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  • Association between Increased Number of Septal Branches within the Myocardial Bridge and Abnormal Diastolic-Fractional Flow Reserve

    Takumi Kimura, Shigemitsu Tanaka, Kozo Okada, Hideki Kitahara, Yuhei Kobayashi, Yukari Kobayashi, Vedant S. Pargaonkar, Paul Yock, Peter J. Fitzgerald, Yasuhiro Honda, Ian S. Rogers, Jennifer A. Tremmel, Ingela Schnittger

    JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY   66 ( 15 )   B139 - B140   2015.10

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    DOI： 10.1016/j.jacc.2015.08.964

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  • Impact of Stent Size Selection on Acute and Long-Term Outcomes after Drug-Eluting Stent Implantation in De Novo Coronary Lesions

    Hideki Kitahara, Kozo Okada, Yuhei Kobayashi, Takumi Kimura, Paul Yock, Peter J. Fitzgerald, Yasuhiro Honda

    JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY   66 ( 15 )   B225 - B225   2015.10

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    DOI： 10.1016/j.jacc.2015.08.1025

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  • Variability in Quantitative Precision of Intravascular Imaging Modalities: Head-to-Head Comparison of Currently Available Coronary Imaging Systems

    Yuhei Kobayashi, Hideki Kitahara, Shigemitsu Tanaka, Kozo Okada, Takumi Kimura, Fumiaki Ikeno, Paul Yock, Peter J. Fitzgerald, Yasuhiro Honda

    JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY   66 ( 15 )   B142 - B142   2015.10

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    DOI： 10.1016/j.jacc.2015.08.971

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  • Factors Affecting Quantitative Stent Assessment by Optical Frequency Domain Imaging: In Vivo Direct Comparison with Intravascular Ultrasound

    Yuhei Kobayashi, Hideki Kitahara, Shigemitsu Tanaka, Kozo Okada, Takumi Kimura, Fumiaki Ikeno, Paul Yock, Peter J. Fitzgerald, Yasuhiro Honda

    JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY   66 ( 15 )   B134 - B135   2015.10

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    DOI： 10.1016/j.jacc.2015.08.352

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  • Variability in Quantitative Precision of Intravascular Imaging Modalities: Head-to-Head Comparison of Currently Available Coronary Imaging Systems

    Yuhei Kobayashi, Hideki Kitahara, Shigemitsu Tanaka, Kozo Okada, Takumi Kimura, Fumiaki Ikeno, Paul Yock, Peter J. Fitzgerald, Yasuhiro Honda

    JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY   66 ( 15 )   B142 - B142   2015.10

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    DOI： 10.1016/j.jacc.2015.08.971

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  • Assessment of Bioresorbable Scaffold With a Novel High-Definition 60MHz IVUS Imaging System: Comparison With Conventional 40MHz IVUS and Optical Coherence Tomography

    Kozo Okada, Hideki Kitahara, Yoshiaki Mitsutake, Shigemitsu Tanaka, Paul Yock, Peter J. Fitzgerald, Fumiaki Ikeno, Yasuhiro Honda

    JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY   66 ( 15 )   B146 - B147   2015.10

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    DOI： 10.1016/j.jacc.2015.08.980

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  • Assessment of Bioresorbable Scaffold With a Novel High-Definition 60MHz IVUS Imaging System: Comparison With Conventional 40MHz IVUS and Optical Coherence Tomography

    Kozo Okada, Hideki Kitahara, Yoshiaki Mitsutake, Shigemitsu Tanaka, Paul Yock, Peter J. Fitzgerald, Fumiaki Ikeno, Yasuhiro Honda

    JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY   66 ( 15 )   B146 - B147   2015.10

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    DOI： 10.1016/j.jacc.2015.08.980

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  • Physiologic Assessment of Intermediate Coronary Artery Stenosis by Intravascular Ultrasound Radiofrequency Signal Analysis of Blood Speckles: A Comparison with Fractional Flow Reserve and Instantaneous Wave-Free Ratio

    Kozo Okada, Kiyoshi Hibi, Kensuke Matsushita, Hideki Kitahara, Peter J. Fitzgerald, Satoshi Umemura, Yasuhiro Honda, Kazuo Kimura

    JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY   66 ( 15 )   B59 - B60   2015.10

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    DOI： 10.1016/j.jacc.2015.08.175

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  • Physiologic Assessment of Intermediate Coronary Artery Stenosis by Intravascular Ultrasound Radiofrequency Signal Analysis of Blood Speckles: A Comparison with Fractional Flow Reserve and Instantaneous Wave-Free Ratio

    Kozo Okada, Kiyoshi Hibi, Kensuke Matsushita, Hideki Kitahara, Peter J. Fitzgerald, Satoshi Umemura, Yasuhiro Honda, Kazuo Kimura

    JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY   66 ( 15 )   B59 - B60   2015.10

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    DOI： 10.1016/j.jacc.2015.08.175

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  • Head-to-Head Comparison of Two Commercially Available Automated Detection Algorithms for Lumen Contour in Optical Coherence Tomography Analysis

    Kyuhachi Otagiri, Hideki Kitahara, Shigemitsu Tanaka, Kozo Okada, Yuhei Kobayashi, Takashi Miura, Soichiro Ebisawa, Yusuke Miyashita, Hiroshi Kitabayashi, Paul Yock, Peter J. Fitzgerald, Uichi Ikeda, Yasuhiro Honda

    JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY   66 ( 15 )   B136 - B136   2015.10

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    DOI： 10.1016/j.jacc.2015.08.356

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  • Association between blood glucose variability and coronary plaque instability in patients with acute coronary syndromes Reviewed

    Kozo Okada, Kiyoshi Hibi, Masaomi Gohbara, Shunsuke Kataoka, Keiko Takano, Eiichi Akiyama, Yasushi Matsuzawa, Kenichiro Saka, Nobuhiko Maejima, Mitsuaki Endo, Noriaki Iwahashi, Kengo Tsukahara, Masami Kosuge, Toshiaki Ebina, Peter J. Fitzgerald, Yasuhiro Honda, Satoshi Umemura, Kazuo Kimura

    Cardiovascular Diabetology   14 ( 1 )   S13   2015.8

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    DOI： 10.1186/s12933-015-0275-3

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  • PARADOXICAL ARTERIAL REMODELING OF THE PROXIMAL SEGMENT OF THE LEFT ANTERIOR DESCENDING ARTERY PREDICTS LONG-TERM MORTALITY AFTER HEART TRANSPLANTATION

    Kozo Okada, Hideki Kitahara, Hyoung-Mo Yang, Shigemitsu Tanaka, Yuhei Kobayashi, Helen Luikart, Paul Yock, Alan Yeung, Peter Fitzgerald, Kiran Khush, Yasuhiro Honda, William Fearon

    JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY   65 ( 10 )   A1740 - A1740   2015.3

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    DOI： 10.1016/S0735-1097(15)61740-5

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  • IMPACT OF MYOCARDIAL BRIDGING ON CORONARY ARTERY PLAQUE FORMATION AND LONG-TERM MORTALITY AFTER HEART TRANSPLANTATION

    Shigemitsu Tanaka, Kozo Okada, Hideki Kitahara, Yuhei Kobayashi, Helen Luikart, Paul Yock, Alan Yeung, Ingela Schnittger, Peter Fitzgerald, Kiran Khush, William Fearon, Yasuhiro Honda

    JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY   65 ( 10 )   A1741 - A1741   2015.3

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    DOI： 10.1016/S0735-1097(15)61741-7

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  • INVASIVE CORONARY PHYSIOLOGY AT ONE YEAR PREDICTS LATE MORTALITY AFTER HEART TRANSPLANTATION

    Hyoung-Mo Yang, Kozo Okada, Garrett Cohen, Calvin Strehl, Helen Luikart, Hannah Valantine, Yasuhiro Honda, Kiran Khush, William Fearon

    JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY   65 ( 10 )   A1685 - A1685   2015.3

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    DOI： 10.1016/S0735-1097(15)61685-0

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  • IMPACT OF MYOCARDIAL BRIDGING ON CORONARY ARTERY PLAQUE FORMATION AND LONG-TERM MORTALITY AFTER HEART TRANSPLANTATION

    Shigemitsu Tanaka, Kozo Okada, Hideki Kitahara, Yuhei Kobayashi, Helen Luikart, Paul Yock, Alan Yeung, Ingela Schnittger, Peter Fitzgerald, Kiran Khush, William Fearon, Yasuhiro Honda

    JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY   65 ( 10 )   A1741 - A1741   2015.3

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    DOI： 10.1016/S0735-1097(15)61741-7

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  • INVASIVE CORONARY PHYSIOLOGY AT ONE YEAR PREDICTS LATE MORTALITY AFTER HEART TRANSPLANTATION

    Hyoung-Mo Yang, Kozo Okada, Garrett Cohen, Calvin Strehl, Helen Luikart, Hannah Valantine, Yasuhiro Honda, Kiran Khush, William Fearon

    JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY   65 ( 10 )   A1685 - A1685   2015.3

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    DOI： 10.1016/S0735-1097(15)61685-0

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  • ASSOCIATION OF PERIARTERIAL NEOVASCULARIZATION WITH PROGRESSION OF CARDIAC ALLOGRAFT VASCULOPATHY AND LONG-TERM CLINICAL OUTCOMES IN HEART TRANSPLANT RECIPIENTS

    Hideki Kitahara, Kozo Okada, Shigemitsu Tanaka, Hyoung-Mo Yang, Yuhei Kobayashi, Takumi Kimura, Helen Luikart, Paul Yock, Alan Yeung, Peter Fitzgerald, Kiran Khush, William Fearon, Yasuhiro Honda

    JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY   65 ( 10 )   A1710 - A1710   2015.3

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    DOI： 10.1016/S0735-1097(15)61710-7

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  • ASSOCIATION OF PERIARTERIAL NEOVASCULARIZATION WITH PROGRESSION OF CARDIAC ALLOGRAFT VASCULOPATHY AND LONG-TERM CLINICAL OUTCOMES IN HEART TRANSPLANT RECIPIENTS

    Hideki Kitahara, Kozo Okada, Shigemitsu Tanaka, Hyoung-Mo Yang, Yuhei Kobayashi, Takumi Kimura, Helen Luikart, Paul Yock, Alan Yeung, Peter Fitzgerald, Kiran Khush, William Fearon, Yasuhiro Honda

    JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY   65 ( 10 )   A1710 - A1710   2015.3

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    DOI： 10.1016/S0735-1097(15)61710-7

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  • PARADOXICAL ARTERIAL REMODELING OF THE PROXIMAL SEGMENT OF THE LEFT ANTERIOR DESCENDING ARTERY PREDICTS LONG-TERM MORTALITY AFTER HEART TRANSPLANTATION

    Kozo Okada, Hideki Kitahara, Hyoung-Mo Yang, Shigemitsu Tanaka, Yuhei Kobayashi, Helen Luikart, Paul Yock, Alan Yeung, Peter Fitzgerald, Kiran Khush, Yasuhiro Honda, William Fearon

    JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY   65 ( 10 )   A1740 - A1740   2015.3

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    DOI： 10.1016/S0735-1097(15)61740-5

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  • Association of Periarterial Low-Echoic Appearance with Progression of Coronary Allograft Vasculopathy and Long-Term Clinical Outcomes in Heart Transplant Patients

    Hideki Kitahara, Kozo Okada, Hyoung-Mo Yang, Hong-Seok Lim, Kyuhachi Otagiri, Shigemitsu Tanaka, Yuhei Kobayashi, Paul G. Yock, Alan C. Yeung, Peter J. Fitzgerald, Kiran K. Khush, William F. Fearon, Yasuhiro Honda

    CIRCULATION   130   2014.11

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  • Association of Periarterial Low-Echoic Appearance with Progression of Coronary Allograft Vasculopathy and Long-Term Clinical Outcomes in Heart Transplant Patients

    Hideki Kitahara, Kozo Okada, Hyoung-Mo Yang, Hong-Seok Lim, Kyuhachi Otagiri, Shigemitsu Tanaka, Yuhei Kobayashi, Paul G. Yock, Alan C. Yeung, Peter J. Fitzgerald, Kiran K. Khush, William F. Fearon, Yasuhiro Honda

    CIRCULATION   130   2014.11

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  • Impact of Myocardial Bridging on Stent-edge Compression in Left Anterior Descending Coronary Arteries

    Shigemitsu Tanaka, Ryotaro Yamada, Yuhei Kobayashi, Kozo Okada, Kyuhachi Otagiri, Hideki Kitahara, Paul G. Yock, Peter J. Fitzgerald, Yasuhiro Honda

    CIRCULATION   130   2014.11

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  • Coronary Artery Negative Remodeling and Intimal Thickening Predict Long-Term Clinical Outcomes After Heart Transplantation

    Kozo Okada, Hideki Kitahara, Hyoung-Mo Yang, Hong-Seok Lim, Kyuhachi Otagiri, Shigemitsu Tanaka, Yuhei Kobayashi, Paul G. Yock, Alan C. Yeung, Peter J. Fitzgerald, Kiran K. Khush, Yasuhiro Honda, William F. Fearon

    CIRCULATION   130   2014.11

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  • Coronary Artery Negative Remodeling and Intimal Thickening Predict Long-Term Clinical Outcomes After Heart Transplantation

    Kozo Okada, Hideki Kitahara, Hyoung-Mo Yang, Hong-Seok Lim, Kyuhachi Otagiri, Shigemitsu Tanaka, Yuhei Kobayashi, Paul G. Yock, Alan C. Yeung, Peter J. Fitzgerald, Kiran K. Khush, Yasuhiro Honda, William F. Fearon

    CIRCULATION   130   2014.11

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  • Geographic Distribution of Cardiac Allograft Vasculopathy Associated With Acute Cellular Rejection: A Serial Three-Dimensional IVUS Study of Heart Transplant Recipients

    Kozo Okada, Hideki Kitahara, Hyoung-Mo Yang, Hong-Seok Lim, Kyuhachi Otagiri, Shigemitsu Tanaka, Yuhei Kobayashi, Paul G. Yock, Alan C. Yeung, Peter J. Fitzgerald, Kiran K. Khush, William F. Fearon, Yasuhiro Honda

    CIRCULATION   130   2014.11

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  • Impact of Myocardial Bridging on Stent-edge Compression in Left Anterior Descending Coronary Arteries

    Shigemitsu Tanaka, Ryotaro Yamada, Yuhei Kobayashi, Kozo Okada, Kyuhachi Otagiri, Hideki Kitahara, Paul G. Yock, Peter J. Fitzgerald, Yasuhiro Honda

    CIRCULATION   130   2014.11

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  • Geographic Distribution of Cardiac Allograft Vasculopathy Associated With Acute Cellular Rejection: A Serial Three-Dimensional IVUS Study of Heart Transplant Recipients

    Kozo Okada, Hideki Kitahara, Hyoung-Mo Yang, Hong-Seok Lim, Kyuhachi Otagiri, Shigemitsu Tanaka, Yuhei Kobayashi, Paul G. Yock, Alan C. Yeung, Peter J. Fitzgerald, Kiran K. Khush, William F. Fearon, Yasuhiro Honda

    CIRCULATION   130   2014.11

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  • Appropriate Intravascular Ultrasound Measurement Intervals for Assessment of Cardiac Allograft Vasculopathy after Heart Transplantation

    Kozo Okada, Hideki Kitahara, Kyuhachi Otagiri, Shigemitsu Tanaka, Yuhei Kobayashi, Paul Yock, Alan Yeung, Peter J. Fitzgerald, Hannah A. Valantine, Kiran K. Khush, William F. Fearon, Yasuhiro Honda

    JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY   64 ( 11 )   B105 - B105   2014.9

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    DOI： 10.1016/j.jacc.2014.07.407

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  • Head-to-Head Comparison of Automated versus Manual Detection for Lumen Contour and Stent Struts in Optical Coherence Tomography Analysis

    Kyuhachi Otagiri, Hideki Kitahara, Tomonori Yaguchi, Shigemitsu Tanaka, Kozo Okada, Yuhei Kobayashi, Takashi Miura, Soichiro Ebisawa, Yusuke Miyashita, Paul Yock, Peter J. Fitzgerald, Uichi Ikeda, Yasuhiro Honda

    JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY   64 ( 11 )   B116 - B116   2014.9

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    DOI： 10.1016/j.jacc.2014.07.444

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  • Head-to-Head Comparison of Automated versus Manual Detection for Lumen Contour and Stent Struts in Optical Coherence Tomography Analysis

    Kyuhachi Otagiri, Hideki Kitahara, Tomonori Yaguchi, Shigemitsu Tanaka, Kozo Okada, Yuhei Kobayashi, Takashi Miura, Soichiro Ebisawa, Yusuke Miyashita, Paul Yock, Peter J. Fitzgerald, Uichi Ikeda, Yasuhiro Honda

    JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY   64 ( 11 )   B116 - B116   2014.9

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    DOI： 10.1016/j.jacc.2014.07.444

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  • Appropriate Intravascular Ultrasound Measurement Intervals for Assessment of Cardiac Allograft Vasculopathy after Heart Transplantation

    Kozo Okada, Hideki Kitahara, Kyuhachi Otagiri, Shigemitsu Tanaka, Yuhei Kobayashi, Paul Yock, Alan Yeung, Peter J. Fitzgerald, Hannah A. Valantine, Kiran K. Khush, William F. Fearon, Yasuhiro Honda

    JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY   64 ( 11 )   B105 - B105   2014.9

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    DOI： 10.1016/j.jacc.2014.07.407

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  • Validation of High Speed Pullback of a Novel High-Definition Intravascular Ultrasound System

    Kaori Nakagawa, Shigemitsu Tanaka, Hideki Kitahara, Yuhei Kobayashi, Kozo Okada, Kyuhachi Otagiri, Paul Yock, Peter J. Fitzgerald, Yasuhiro Honda, Alan Yeung, Fumiaki Ikeno

    JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY   64 ( 11 )   B102 - B102   2014.9

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    DOI： 10.1016/j.jacc.2014.07.399

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  • Precision of a Novel High-Definition 60MHz IVUS in Quantitative Measurement: Comparison with Conventional 40MHz IVUS and Optical Coherence Tomography

    Yuhei Kobayashi, Hideki Kitahara, Shigemitsu Tanaka, Kaori Nakagawa, Kozo Okada, Kyuhachi Otagiri, Paul Yock, Peter Fitzgerald, Fumiaki Ikeno, Yasuhiro Honda

    JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY   64 ( 11 )   B105 - B106   2014.9

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    DOI： 10.1016/j.jacc.2014.07.410

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  • Precision of a Novel High-Definition 60MHz IVUS in Quantitative Measurement: Comparison with Conventional 40MHz IVUS and Optical Coherence Tomography

    Yuhei Kobayashi, Hideki Kitahara, Shigemitsu Tanaka, Kaori Nakagawa, Kozo Okada, Kyuhachi Otagiri, Paul Yock, Peter Fitzgerald, Fumiaki Ikeno, Yasuhiro Honda

    JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY   64 ( 11 )   B105 - B106   2014.9

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    DOI： 10.1016/j.jacc.2014.07.410

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  • Transformation of Attenuated-Signal Plaque into Calcified Plaque After DES Implantation

    Hideki Kitahara, Kyuhachi Otagiri, Kozo Okada, Shigemitsu Tanaka, Yuhei Kobayashi, Paul Yock, Peter J. Fitzgerald, Yasuhiro Honda

    JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY   64 ( 11 )   B102 - B102   2014.9

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    DOI： 10.1016/j.jacc.2014.07.397

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  • Transformation of Attenuated-Signal Plaque into Calcified Plaque After DES Implantation

    Hideki Kitahara, Kyuhachi Otagiri, Kozo Okada, Shigemitsu Tanaka, Yuhei Kobayashi, Paul Yock, Peter J. Fitzgerald, Yasuhiro Honda

    JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY   64 ( 11 )   B102 - B102   2014.9

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    DOI： 10.1016/j.jacc.2014.07.397

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  • Attenuated-Signal Plaque and Cardiac Allograft Vasculopathy: A Serial Volumetric IVUS Study of Heart Transplant Recipients

    Kozo Okada, Hideki Kitahara, Kyuhachi Otagiri, Shigemitsu Tanaka, Yuhei Kobayashi, Paul Yock, Alan Yeung, Peter Fitzgerald, Hannah A. Valantine, Kiran K. Khush, William F. Fearon, Yasuhiro Honda

    JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY   64 ( 11 )   B102 - B102   2014.9

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    DOI： 10.1016/j.jacc.2014.07.398

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  • Attenuated-Signal Plaque and Cardiac Allograft Vasculopathy: A Serial Volumetric IVUS Study of Heart Transplant Recipients

    Kozo Okada, Hideki Kitahara, Kyuhachi Otagiri, Shigemitsu Tanaka, Yuhei Kobayashi, Paul Yock, Alan Yeung, Peter Fitzgerald, Hannah A. Valantine, Kiran K. Khush, William F. Fearon, Yasuhiro Honda

    JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY   64 ( 11 )   B102 - B102   2014.9

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    DOI： 10.1016/j.jacc.2014.07.398

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  • Validation of High Speed Pullback of a Novel High-Definition Intravascular Ultrasound System

    Kaori Nakagawa, Shigemitsu Tanaka, Hideki Kitahara, Yuhei Kobayashi, Kozo Okada, Kyuhachi Otagiri, Paul Yock, Peter J. Fitzgerald, Yasuhiro Honda, Alan Yeung, Fumiaki Ikeno

    JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY   64 ( 11 )   B102 - B102   2014.9

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    DOI： 10.1016/j.jacc.2014.07.399

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  • ASSOCIATION BETWEEN ABDOMINAL FAT DISTRIBUTION AND CORONARY TISSUE CHARACTERISTICS IN PATIENTS WITH ACUTE CORONARY SYNDROMES

    Kozo Okada, Kiyoshi Hibi, Yasuhiro Honda, Toshiaki Ebina, Kengo Tsukahara, Masami Kosuge, Yoshio Tahara, Noriaki Iwahashi, Nobuhiko Maejima, Masaaki Konishi, Eiichi Akiyama, Keiko Takano, Naoki Nakayama, Masaomi Gohbara, Zenko Nagashima, Shunsuke Kataoka, Hiroyuki Suzuki, Satoshi Umemura, Kazuo Kimura

    JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY   63 ( 12 )   A1796 - A1796   2014.4

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    DOI： 10.1016/S0735-1097(14)61799-X

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  • VOLUMETRIC VERSUS PLANAR INTRAVASCULAR ULTRASOUND ANALYSIS TO ASSESS SEVERITY OF CARDIAC ALLOGRAFT VASCULOPATHY

    Kozo Okada, Hideki Kitahara, Kyuhachi Otagiri, Shigemitsu Tanaka, Yuhei Kobayashi, Paul Yock, Alan Yeung, Hannah Valantine, Kiran Khush, William Fearon, Peter Fitzgerald, Yasuhiro Honda

    JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY   63 ( 12 )   A1765 - A1765   2014.4

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    DOI： 10.1016/S0735-1097(14)61768-X

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  • VOLUMETRIC VERSUS PLANAR INTRAVASCULAR ULTRASOUND ANALYSIS TO ASSESS SEVERITY OF CARDIAC ALLOGRAFT VASCULOPATHY

    Kozo Okada, Hideki Kitahara, Kyuhachi Otagiri, Shigemitsu Tanaka, Yuhei Kobayashi, Paul Yock, Alan Yeung, Hannah Valantine, Kiran Khush, William Fearon, Peter Fitzgerald, Yasuhiro Honda

    JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY   63 ( 12 )   A1765 - A1765   2014.4

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    DOI： 10.1016/S0735-1097(14)61768-X

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  • RELATIONSHIP BETWEEN BLOOD FLOW VELOCITY AND RADIOFREQUENCY SIGNAL ANALYSIS OF BLOOD SPECKLES: AN EXPERIMENTAL STUDY USING INTEGRATED BACKSCATTER IVUS

    Hideki Kitahara, Shigemitsu Tanaka, Kyuhachi Otagiri, Yuhei Kobayashi, Kozo Okada, Kaori Nakagawa, Fumiaki Ikeno, Paul Yock, Peter Fitzgerald, Yasuhiro Honda

    JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY   63 ( 12 )   A1776 - A1776   2014.4

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    DOI： 10.1016/S0735-1097(14)61779-4

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  • RELATIONSHIP BETWEEN BLOOD FLOW VELOCITY AND RADIOFREQUENCY SIGNAL ANALYSIS OF BLOOD SPECKLES: AN EXPERIMENTAL STUDY USING INTEGRATED BACKSCATTER IVUS

    Hideki Kitahara, Shigemitsu Tanaka, Kyuhachi Otagiri, Yuhei Kobayashi, Kozo Okada, Kaori Nakagawa, Fumiaki Ikeno, Paul Yock, Peter Fitzgerald, Yasuhiro Honda

    JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY   63 ( 12 )   A1776 - A1776   2014.4

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  • ASSOCIATION BETWEEN ABDOMINAL FAT DISTRIBUTION AND CORONARY TISSUE CHARACTERISTICS IN PATIENTS WITH ACUTE CORONARY SYNDROMES

    Kozo Okada, Kiyoshi Hibi, Yasuhiro Honda, Toshiaki Ebina, Kengo Tsukahara, Masami Kosuge, Yoshio Tahara, Noriaki Iwahashi, Nobuhiko Maejima, Masaaki Konishi, Eiichi Akiyama, Keiko Takano, Naoki Nakayama, Masaomi Gohbara, Zenko Nagashima, Shunsuke Kataoka, Hiroyuki Suzuki, Satoshi Umemura, Kazuo Kimura

    JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY   63 ( 12 )   A1796 - A1796   2014.4

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  • Glycemic Variability Determined by a Continuous Glucose Monitoring System Predicts the Extent of the Peri-Infarct Zone and Left Ventricular Remodeling in Patients With a First-Time ST-Segment Elevation Myocardial Infarction.: Cardiac MRI study

    Masaomi Gohbara, Noriaki Iwahashi, Shunsuke Kataoka, Kozo Okada, Masaaki Konishi, Nobuhiko Maejima, Kengo Tsukahara, Yoshio Tahara, Kiyoshi Hibi, Masami Kosuge, Toshiaki Ebina, Satoshi Umemura, Kazuo Kimura

    CIRCULATION   128 ( 22 )   2013.11

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  • Clinical Significance of Blood Glucose Variability Pattern in the Acute Phase of ST-segment Myocardial Infarction (STEMI)

    Kozo Okada, Masaomi Gohbara, Shunsuke Kataoka, Kengo Tsukahara, Toshiaki Ebina, Kiyoshi Hibi, Masami Kosuge, Yoshio Tahara, Nobuhiko Maejima, Noriaki Iwahashi, Masaaki Konishi, Yasushi Matsuzawa, Eiichi Akiyama, Keiko Takano, Naoki Nakayama, Zenko Nagashima, Hiroyuki Suzuki, Shunsuke Matsushita, Satoshi Umemura, Kazuo Kimura

    CIRCULATION   128 ( 22 )   2013.11

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  • Clinical Significance of Blood Glucose Variability Pattern in the Acute Phase of ST-segment Myocardial Infarction (STEMI)

    Kozo Okada, Masaomi Gohbara, Shunsuke Kataoka, Kengo Tsukahara, Toshiaki Ebina, Kiyoshi Hibi, Masami Kosuge, Yoshio Tahara, Nobuhiko Maejima, Noriaki Iwahashi, Masaaki Konishi, Yasushi Matsuzawa, Eiichi Akiyama, Keiko Takano, Naoki Nakayama, Zenko Nagashima, Hiroyuki Suzuki, Shunsuke Matsushita, Satoshi Umemura, Kazuo Kimura

    CIRCULATION   128 ( 22 )   2013.11

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  • Association between Glycemic Variability and Coronary Tissue Characteristics in Patients with Acute Coronary Syndromes

    Kozo Okada, Kiyoshi Hibi, Yasuhiro Honda, Masaomi Gobara, Shunsuke Kataoka, Toshiaki Ebina, Masami Kosuge, Yoshio Tahara, Kengo Tsukahara, Nobuhiko Maejima, Noriaki Iwahashi, Masaaki Konishi, Yasushi Matsuzawa, Eiichi Akiyama, Naoki Nakayama, Zenko Nagashima, Hiroyuki Suzuki, Satoshi Umemura, Kazuo Kimura

    JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY   62 ( 18 )   B195 - B195   2013.10

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    DOI： 10.1016/j.jacc.2013.08.1391

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  • Association between Glycemic Variability and Coronary Tissue Characteristics in Patients with Acute Coronary Syndromes

    Kozo Okada, Kiyoshi Hibi, Yasuhiro Honda, Masaomi Gobara, Shunsuke Kataoka, Toshiaki Ebina, Masami Kosuge, Yoshio Tahara, Kengo Tsukahara, Nobuhiko Maejima, Noriaki Iwahashi, Masaaki Konishi, Yasushi Matsuzawa, Eiichi Akiyama, Naoki Nakayama, Zenko Nagashima, Hiroyuki Suzuki, Satoshi Umemura, Kazuo Kimura

    JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY   62 ( 18 )   B195 - B195   2013.10

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    DOI： 10.1016/j.jacc.2013.08.1391

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  • Acute Stent Expansion in the Latest-Generation Drug-Eluting Stent Platforms: An Experimental Study Using Optical Coherence Tomography

    Hideki Kitahara, Katsuhisa Waseda, Ryotaro Yamada, Kyuhachi Otagiri, Shigemitsu Tanaka, Yuhei Kobayashi, Kozo Okada, Kaori Nakagawa, Fumiaki Ikeno, Paul Yock, Peter J. Fitzgerald, Yasuhiro Honda

    JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY   62 ( 18 )   B180 - B180   2013.10

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    DOI： 10.1016/j.jacc.2013.08.1341

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  • Acute Stent Expansion in the Latest-Generation Drug-Eluting Stent Platforms: An Experimental Study Using Optical Coherence Tomography

    Hideki Kitahara, Katsuhisa Waseda, Ryotaro Yamada, Kyuhachi Otagiri, Shigemitsu Tanaka, Yuhei Kobayashi, Kozo Okada, Kaori Nakagawa, Fumiaki Ikeno, Paul Yock, Peter J. Fitzgerald, Yasuhiro Honda

    JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY   62 ( 18 )   B180 - B180   2013.10

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    DOI： 10.1016/j.jacc.2013.08.1341

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  • CLINICAL USEFULNESS OF 3D SPECKLE TRACKING STRAIN ACUTELY ONSET AFTER STEMI

    Noriaki Iwahashi, Masaomi Gohbara, Kozo Okada, Nobuhiko Maejima, Mitsuaki Endo, Kengo Tsukahara, Yoshio Tahara, Kiyoshi Hibi, Masami Kosuge, Toshiaki Ebina, Satoshi Umemura, Kazuo Kimura

    JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY   61 ( 10 )   E1102 - E1102   2013.3

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    DOI： 10.1016/S0735-1097(13)61102-X

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  • THE EFFECT OF NIGHTTIME BLOOD PRESSURE VARIABILITY ON LEFT VENTRICULAR HYPERTROPHY AND CAROTID INTIMA MEDIA THICKNESS IN PATIENTS WITH NSTEMI

    Shunsuke Kataoka, Kozo Okada, Masaomi Gohbara, Noriaki Iwahashi, Kengo Tsukahara, Yoshio Tahara, Kiyoshi Hibi, Masami Kosuge, Toshiaki Ebina, Satoshi Umemura, Kazuo Kimura

    JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY   61 ( 10 )   E1475 - E1475   2013.3

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    DOI： 10.1016/S0735-1097(13)61475-8

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  • THE EFFECT OF NIGHTTIME BLOOD PRESSURE VARIABILITY ON LEFT VENTRICULAR HYPERTROPHY AND CAROTID INTIMA MEDIA THICKNESS IN PATIENTS WITH NSTEMI

    Shunsuke Kataoka, Kozo Okada, Masaomi Gohbara, Noriaki Iwahashi, Kengo Tsukahara, Yoshio Tahara, Kiyoshi Hibi, Masami Kosuge, Toshiaki Ebina, Satoshi Umemura, Kazuo Kimura

    JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY   61 ( 10 )   E1475 - E1475   2013.3

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    DOI： 10.1016/S0735-1097(13)61475-8

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  • MONOCYTOSIS AFTER MYOCARDIAL INFARCTION ACCELERATES ATHEROSCLEROSIS: RESULTS OF A FIVE-YEAR FOLLOW-UP STUDY

    Keiko Takano, Kiyoshi Hibi, Masaaki Konishi, Yasushi Matsuzawa, Toshiaki Ebina, Masami Kosuge, Yoshio Tahara, Kengo Tsukahara, Mitsuaki Endo, Noriaki Iwahashi, Nobuhiko Maejima, Kenichirou Saka, Kozo Okada, Eiichi Akiyama, Masaomi Gobara, Zenkou Nagashima, Hiroyuki Suzuki, Kazuo Kimura, Satoshi Umemura

    JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY   61 ( 10 )   E198 - E198   2013.3

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    DOI： 10.1016/S0735-1097(13)60199-0

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  • ASSOCIATION BETWEEN HIGHER GLUCOSE VARIABILITY, DETERMINED BY CONTINUOUS GLUCOSE MONITORING SYSTEM, AND POOR CLINICAL CHARACTERISTICS IN STEMI PATIENTS WITH DYSGLYCEMIA, IN COMPARISON WITH CONVENTIONAL GLYCEMIC PARAMETERS

    Kozo Okada, Shunsuke Kataoka, Masami Gohbara, Hiroyuki Suzuki, Zenko Nagashima, Keiko Takano, Eiichi Akiyama, Yasushi Matsuzawa, Masaaki Konishi, Nobuhiko Maejima, Mitsuaki Endo, Noriaki Iwahashi, Kengo Tsukahara, Yoshio Tahara, Kenichiro Saka, Kiyoshi Hibi, Masami Kosuge, Toshiaki Ebina, Satoshi Umemura, Kazuo Kimura

    JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY   61 ( 10 )   E93 - E93   2013.3

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    DOI： 10.1016/S0735-1097(13)60094-7

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  • ASSOCIATION BETWEEN HIGHER GLUCOSE VARIABILITY, DETERMINED BY CONTINUOUS GLUCOSE MONITORING SYSTEM, AND POOR CLINICAL CHARACTERISTICS IN STEMI PATIENTS WITH DYSGLYCEMIA, IN COMPARISON WITH CONVENTIONAL GLYCEMIC PARAMETERS

    Kozo Okada, Shunsuke Kataoka, Masami Gohbara, Hiroyuki Suzuki, Zenko Nagashima, Keiko Takano, Eiichi Akiyama, Yasushi Matsuzawa, Masaaki Konishi, Nobuhiko Maejima, Mitsuaki Endo, Noriaki Iwahashi, Kengo Tsukahara, Yoshio Tahara, Kenichiro Saka, Kiyoshi Hibi, Masami Kosuge, Toshiaki Ebina, Satoshi Umemura, Kazuo Kimura

    JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY   61 ( 10 )   E93 - E93   2013.3

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    DOI： 10.1016/S0735-1097(13)60094-7

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  • TWISTING MOTION ESTIMATED BY 3D SPECKLE-TRACKING STRAIN ACUTELY ONSET AFTER STEMI PREDICTS INFARCT SIZE AND LV REMODELING

    Noriaki Iwahashi, Masaomi Gohbara, Kozo Okada, Nobuhiko Maejima, Mitsuaki Endo, Kengo Tsukahara, Yoshio Tahara, Kiyoshi Hibi, Masami Kosuge, Toshiaki Ebina, Satoshi Umemura, Kazuo Kimura

    JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY   61 ( 10 )   E908 - E908   2013.3

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    DOI： 10.1016/S0735-1097(13)60908-0

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  • TWISTING MOTION ESTIMATED BY 3D SPECKLE-TRACKING STRAIN ACUTELY ONSET AFTER STEMI PREDICTS INFARCT SIZE AND LV REMODELING

    Noriaki Iwahashi, Masaomi Gohbara, Kozo Okada, Nobuhiko Maejima, Mitsuaki Endo, Kengo Tsukahara, Yoshio Tahara, Kiyoshi Hibi, Masami Kosuge, Toshiaki Ebina, Satoshi Umemura, Kazuo Kimura

    JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY   61 ( 10 )   E908 - E908   2013.3

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    DOI： 10.1016/S0735-1097(13)60908-0

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  • Higher Active Glucagon-Like Peptide-1 Level on Admission Was Associated with Reduced Infarct Size in Patients with ST Elevation Acute Myocardial Infarction

    Masaaki Konishi, Masaomi Gobara, Eiichi Akiyama, Kozo Okada, Yasushi Matsuzawa, Kenichirou Saka, Nobuhiko Maejima, Noriaki Iwahashi, Mitsuaki Endo, Kengo Tsukahara, Kiyoshi Hibi, Toshiaki Ebina, Kazuo Kimura, Satoshi Umemura

    CIRCULATION   126 ( 21 )   2012.11

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  • Left Ventricular Dyssynchrony Estimated by 3D Speckle Tracking Echocardiography Acutely Onset after ST-Elevation Myocardial Infarction Predicts Final Infarct Size and Remodeling

    Noriaki Iwahashi, Kazuo Kimura, Masaomi Gohbara, Zenko Nagashima, Kozo Okada, Mistuaki Endo, Nobuhiko Maejima, Kengo Tsukahara, Yoshio Tahara, Kiyoshi Hibi, Masami Kosuge, Toshiaki Ebina, Taro Hattori, Mochizuki Hidekazu, Atsuyoshi Miyauchi, Yukiko Ouchi, Eiji Ishikawa, Satoshi Umemura

    CIRCULATION   126 ( 21 )   2012.11

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  • Paradoxical Hemoconcentration on Admission of Acute Hypertensive Heart Failure Syndrome

    Masaaki Konishi, Masaomi Gobara, Eiichi Akiyama, Kozo Okada, Yasushi Matsuzawa, Kenichirou Saka, Noriaki Iwahashi, Nobuhiko Maejima, Mitsuaki Endo, Kengo Tsukahara, Kiyoshi Hibi, Toshiaki Ebina, Kazuo Kimura, Satoshi Umemura

    CIRCULATION   126 ( 21 )   2012.11

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  • Higher Active Glucagon-Like Peptide-1 Level on Admission Was Associated with Reduced Infarct Size in Patients with ST Elevation Acute Myocardial Infarction

    Masaaki Konishi, Masaomi Gobara, Eiichi Akiyama, Kozo Okada, Yasushi Matsuzawa, Kenichirou Saka, Nobuhiko Maejima, Noriaki Iwahashi, Mitsuaki Endo, Kengo Tsukahara, Kiyoshi Hibi, Toshiaki Ebina, Kazuo Kimura, Satoshi Umemura

    CIRCULATION   126 ( 21 )   2012.11

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  • Left Ventricular Dyssynchrony Estimated by 3D Speckle Tracking Echocardiography Acutely Onset after ST-Elevation Myocardial Infarction Predicts Final Infarct Size and Remodeling

    Noriaki Iwahashi, Kazuo Kimura, Masaomi Gohbara, Zenko Nagashima, Kozo Okada, Mistuaki Endo, Nobuhiko Maejima, Kengo Tsukahara, Yoshio Tahara, Kiyoshi Hibi, Masami Kosuge, Toshiaki Ebina, Taro Hattori, Mochizuki Hidekazu, Atsuyoshi Miyauchi, Yukiko Ouchi, Eiji Ishikawa, Satoshi Umemura

    CIRCULATION   126 ( 21 )   2012.11

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  • Long-term Effects of Ezetimibe Plus Statin Combination vs Double-dose Statin Therapy on Low-density Lipoprotein Cholesterol Lowering in Coronary Artery Disease Patients Pre-treated with Statins; Focus on Proprotein Convertase Subtilisin/Kexin Type 9

    Kozo Okada, Noriaki Iwahashi, Tsutomu Endo, Hideo Himeno, Kazuki Fukui, Shunichi Kobayashi, Makoto Shimizu, Yuji Iwasawa, Yukiko Morita, Atsushi Wada, Tomohiko Shigemasa, Yasuyuki Mochida, Tomoaki Shimizu, Reimin Sawada, Kazuaki Uchino, Satoshi Umemura, Kazuo Kimura

    CIRCULATION   126 ( 21 )   2012.11

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  • Glucose Variability Determined by Continuous Glucose Monitoring System Is More Associated with Poor Clinical Characteristics in ST-Segment Elevation Myocardial Infarction Patients with Type 2 Diabetes Mellitus and Impaired Glucose Tolerance, in Comparison with Hemoglobin A1c Levels

    Kozo Okada, Masaomi Gobara, Noriaki Iwahashi, Zenko Nagashima, Hiroyuki Suzuki, Keiko Takano, Eiichi Akiyama, Yasushi Matsuzawa, Masaaki Konishi, Kenichiro Saka, Nobuhiko Maejima, Mitsuaki Endo, Kengo Tsukahara, Yoshio Tahara, Kiyoshi Hibi, Masami Kosuge, Toshiaki Eniba, Kazuo Kimura

    CIRCULATION   126 ( 21 )   2012.11

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  • Long-term Effects of Ezetimibe Plus Statin Combination vs Double-dose Statin Therapy on Low-density Lipoprotein Cholesterol Lowering in Coronary Artery Disease Patients Pre-treated with Statins; Focus on Proprotein Convertase Subtilisin/Kexin Type 9

    Kozo Okada, Noriaki Iwahashi, Tsutomu Endo, Hideo Himeno, Kazuki Fukui, Shunichi Kobayashi, Makoto Shimizu, Yuji Iwasawa, Yukiko Morita, Atsushi Wada, Tomohiko Shigemasa, Yasuyuki Mochida, Tomoaki Shimizu, Reimin Sawada, Kazuaki Uchino, Satoshi Umemura, Kazuo Kimura

    CIRCULATION   126 ( 21 )   2012.11

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  • Glucose Variability Determined by Continuous Glucose Monitoring System Is More Associated with Poor Clinical Characteristics in ST-Segment Elevation Myocardial Infarction Patients with Type 2 Diabetes Mellitus and Impaired Glucose Tolerance, in Comparison with Hemoglobin A1c Levels

    Kozo Okada, Masaomi Gobara, Noriaki Iwahashi, Zenko Nagashima, Hiroyuki Suzuki, Keiko Takano, Eiichi Akiyama, Yasushi Matsuzawa, Masaaki Konishi, Kenichiro Saka, Nobuhiko Maejima, Mitsuaki Endo, Kengo Tsukahara, Yoshio Tahara, Kiyoshi Hibi, Masami Kosuge, Toshiaki Eniba, Kazuo Kimura

    CIRCULATION   126 ( 21 )   2012.11

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  • Paradoxical Hemoconcentration on Admission of Acute Hypertensive Heart Failure Syndrome

    Masaaki Konishi, Masaomi Gobara, Eiichi Akiyama, Kozo Okada, Yasushi Matsuzawa, Kenichirou Saka, Noriaki Iwahashi, Nobuhiko Maejima, Mitsuaki Endo, Kengo Tsukahara, Kiyoshi Hibi, Toshiaki Ebina, Kazuo Kimura, Satoshi Umemura

    CIRCULATION   126 ( 21 )   2012.11

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  • Relation of Proton pump inhibitor and cytochrome P450 2C19 polymorphisms on pletelet reactivity in patients with acute coronary syndromes

    Zenko Nagashima, Toshiaki Ebina, Mitsuaki Endo, Kiyoshi Hibi, Kazuo Kimura, Nobuhiko Maejima, Zenko Nagashima, Kozo Okada, Kengo Tsukahara, Satoshi Umemura

    JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY   60 ( 17 )   B214 - B214   2012.10

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    DOI： 10.1016/j.jacc.2012.08.774

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  • Relation between peak high sensitivity CRP levels before coronary angiography and culprit lesion morphology in non-ST-segment elevation acute coronary syndrome -An optical coherence tomography study-

    Kenichiro Saka, Kiyoshi Hibi, Nobuhiko Maejima, Kozo Okada, Yasushi Matsuzawa, Masaaki Konishi, Noriaki Iwahashi, Mitsuaki Endo, Kengo Tsukahara, Masami Kosuge, Toshiaki Ebina, Satoshi Umemura, Kazuo Kimura

    JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY   60 ( 17 )   B75 - B76   2012.10

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  • Effect of statin pretreatment on the morphology of coronary culprit plaques in patients with stable angina pectoris -An intravascular ultrasound and optical coherence tomography study-

    Kenichiro Saka, Kiyoshi Hibi, Nobuhiko Maejima, Kozo Okada, Yasushi Matsuzawa, Masaaki Konishi, Noriaki Iwahashi, Mitsuaki Endo, Kengo Tsukahara, Masami Kosuge, Toshiaki Ebina, Satoshi Umemura, Kazuo Kimura

    JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY   60 ( 17 )   B75 - B75   2012.10

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  • Relation between peak high sensitivity CRP levels before coronary angiography and culprit lesion morphology in non-ST-segment elevation acute coronary syndrome -An optical coherence tomography study-

    Kenichiro Saka, Kiyoshi Hibi, Nobuhiko Maejima, Kozo Okada, Yasushi Matsuzawa, Masaaki Konishi, Noriaki Iwahashi, Mitsuaki Endo, Kengo Tsukahara, Masami Kosuge, Toshiaki Ebina, Satoshi Umemura, Kazuo Kimura

    JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY   60 ( 17 )   B75 - B76   2012.10

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  • Relation of Proton pump inhibitor and cytochrome P450 2C19 polymorphisms on pletelet reactivity in patients with acute coronary syndromes

    Zenko Nagashima, Toshiaki Ebina, Mitsuaki Endo, Kiyoshi Hibi, Kazuo Kimura, Nobuhiko Maejima, Zenko Nagashima, Kozo Okada, Kengo Tsukahara, Satoshi Umemura

    JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY   60 ( 17 )   B214 - B214   2012.10

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    DOI： 10.1016/j.jacc.2012.08.774

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  • Effect of statin pretreatment on the morphology of coronary culprit plaques in patients with stable angina pectoris -An intravascular ultrasound and optical coherence tomography study-

    Kenichiro Saka, Kiyoshi Hibi, Nobuhiko Maejima, Kozo Okada, Yasushi Matsuzawa, Masaaki Konishi, Noriaki Iwahashi, Mitsuaki Endo, Kengo Tsukahara, Masami Kosuge, Toshiaki Ebina, Satoshi Umemura, Kazuo Kimura

    JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY   60 ( 17 )   B75 - B75   2012.10

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  • 急性冠症候群 (Special Feature 先読みフローチャートで分かる イラスト&ビジュアルで循環器系救急に強くなる)

    岡田 興造, 木村 一雄

    Emergency care = エマージェンシー・ケア : 日本救急看護学会準機関誌   25 ( 8 )   728 - 737   2012.8

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    CiNii Books

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    Other Link： http://search.jamas.or.jp/link/ui/2012287118

  • THE MECHANISM OF LONG-TERM LOW-DENSITY LIPOPROTEIN CHOLESTEROL LOWERING EFFECT OF EZETIMIBE-PLUS-STATIN COMBINATION THERAPY IN CORONARY ARTERY DISEASE PATIENTS; COMPARED WITH DOUBLE-DOSE STATIN THERAPY

    Kozo Okada, Kazuo Kimura, Noriaki Iwahashi, Tsutomu Endo, Himeno Hideo, Makoto Shimizu, Atsushi Wada, Atsushi Wada, Kazuaki Uchino, Satoshi Umemura

    JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY   59 ( 13 )   E1541 - E1541   2012.3

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    DOI： 10.1016/S0735-1097(12)61542-3

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  • THE MECHANISM OF LONG-TERM LOW-DENSITY LIPOPROTEIN CHOLESTEROL LOWERING EFFECT OF EZETIMIBE-PLUS-STATIN COMBINATION THERAPY IN CORONARY ARTERY DISEASE PATIENTS; COMPARED WITH DOUBLE-DOSE STATIN THERAPY

    Kozo Okada, Kazuo Kimura, Noriaki Iwahashi, Tsutomu Endo, Himeno Hideo, Makoto Shimizu, Atsushi Wada, Atsushi Wada, Kazuaki Uchino, Satoshi Umemura

    JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY   59 ( 13 )   E1541 - E1541   2012.3

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    DOI： 10.1016/S0735-1097(12)61542-3

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  • CARRIAGE OF REDUCED-FUNCTION CYP2C19 ALLELE IS AN INDEPENDENT PREDICTOR OF PERIPROCEDUAL MYOCARDIAL INFARCTION IN PATIENTS WITH NON ST-SEGMENT ELEVATION ACUTE CORONARY SYNDROMES

    Kozo Okada, Kengo Tsukahara, Tsutomu Endo, Kiyoshi Hibi, Kazuaki Uchino, Satoshi Umemura, Kazuo Kimura

    JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY   59 ( 13 )   E528 - E528   2012.3

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    DOI： 10.1016/S0735-1097(12)60529-4

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  • CARRIAGE OF REDUCED-FUNCTION CYP2C19 ALLELE IS AN INDEPENDENT PREDICTOR OF PERIPROCEDUAL MYOCARDIAL INFARCTION IN PATIENTS WITH NON ST-SEGMENT ELEVATION ACUTE CORONARY SYNDROMES

    Kozo Okada, Kengo Tsukahara, Tsutomu Endo, Kiyoshi Hibi, Kazuaki Uchino, Satoshi Umemura, Kazuo Kimura

    JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY   59 ( 13 )   E528 - E528   2012.3

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    DOI： 10.1016/S0735-1097(12)60529-4

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  • Gait Speed and Cardiovascular Events After Myocardial Infarction

    Yasushi Matsuzawa, Masaaki Konishi, Masayoshi Kiyokuni, Eiichi Akiyama, Hiroyuki Suzuki, Toshiaki Ebina, Masami Kosuge, Kiyoshi Hibi, Yoshio Tahara, Kengo Tsukahara, Noriaki Iwahashi, Mitsuaki Endo, Nobuhiko Maejima, Kenichiro Saka, Katsutaka Hashiba, Kozo Okada, Zenko Nagashima, Masataka Taguri, Masaomi Gohbara, Satoshi Umemura, Kazuo Kimura

    CIRCULATION   124 ( 21 )   2011.11

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  • The Prevalence and Comorbidity of Nonspecific Troponin Elevation Detected by Highly Sensitive Assay in Patients with Acute Chest Pain

    Masaaki Konishi, Hiroyuki Suzuki, Kozo Okada, Yasushi Matsuzawa, Katsutaka Hashiba, Kenichirou Saka, Nobuhiko Maejima, Noriaki Iwahashi, Mitsuaki Endo, Kengo Tsukahara, Kiyoshi Hibi, Toshiaki Ebina, Kazuo Kimura, Satoshi Umemura

    CIRCULATION   124 ( 21 )   2011.11

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  • Long-Term Effect of Ezetimibe-Plus-Statin vs Double-Dose Statin on Low-Density Lipoprotein Cholesterol Lowering in Coronary Artery Disease Patients Pre-Treated with a Statin; Focus on Cholesterol Absorption and Synthesis

    Kozo Okada, Kazuo Kimura, Noriaki Iwahashi, Tsutomu Endo, Hideo Himeno, Kazuki Fukui, Shunichi Kobayashi, Makoto Shimizu, Yuji Iwasawa, Yukiko Morita, Atsushi Wada, Tomohiko Shigemasa, Yasuyuki Mochida, Tomoaki Shimizu, Reimin Sawada, Kazuaki Uchino, Satoshi Umemura

    CIRCULATION   124 ( 21 )   2011.11

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  • Long-Term Effect of Ezetimibe-Plus-Statin vs Double-Dose Statin on Low-Density Lipoprotein Cholesterol Lowering in Coronary Artery Disease Patients Pre-Treated with a Statin; Focus on Cholesterol Absorption and Synthesis

    Kozo Okada, Kazuo Kimura, Noriaki Iwahashi, Tsutomu Endo, Hideo Himeno, Kazuki Fukui, Shunichi Kobayashi, Makoto Shimizu, Yuji Iwasawa, Yukiko Morita, Atsushi Wada, Tomohiko Shigemasa, Yasuyuki Mochida, Tomoaki Shimizu, Reimin Sawada, Kazuaki Uchino, Satoshi Umemura

    CIRCULATION   124 ( 21 )   2011.11

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  • The Prevalence and Comorbidity of Nonspecific Troponin Elevation Detected by Highly Sensitive Assay in Patients with Acute Chest Pain

    Masaaki Konishi, Hiroyuki Suzuki, Kozo Okada, Yasushi Matsuzawa, Katsutaka Hashiba, Kenichirou Saka, Nobuhiko Maejima, Noriaki Iwahashi, Mitsuaki Endo, Kengo Tsukahara, Kiyoshi Hibi, Toshiaki Ebina, Kazuo Kimura, Satoshi Umemura

    CIRCULATION   124 ( 21 )   2011.11

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  • Duration of Temporary Inferior Vena Cava Filter for Acute Pulmonary Embolism

    Katsutaka Hashiba, Yasushi Matsuzawa, Toshiaki Ebina, Masami Kosuge, Kiyoshi Hibi, Yoshio Tahara, Kengo Tsukahara, Noriaki Iwahashi, Mitsuaki Endo, Nobuhiko Maejima, Kenichiro Saka, Masaaki Konishi, Kozo Okada, Eiichi Akiyama, Masaomi Goubara, Zenkou Nagashima, Hiroyuki Suzuki, Kazuo Kimura

    CIRCULATION   124 ( 21 )   2011.11

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  • LONG-TERM EFFECT OF EZETIMIBE-STATIN COMBINATION THERAPY ON LOW-DENSITY LIPOPROTEIN CHOLESTEROL LOWERING IN PATIENTS WITH CORONARY ARTERY DISEASE; FOCUS ON CHOLESTEROL ABSORPTION AND SYNTHESIS

    Kozo Okada, Kazuki Fukui, Hideo Himeno, Tutomu Endo, Makoto Shimizu, Shunichi Kobayashi, Tomohiko Shigemasa, Yukiko Morita, Atsushi Wada, Tomoaki Shimizu, Yasuyuki Mochida, Reimin Sawada, Tomoaki Ishigami, Kazuaki Uchino, Noriaki Iwahashi, Kazuo Kimura, Satoshi Umemura

    JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY   57 ( 14 )   E524 - E524   2011.4

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    DOI： 10.1016/S0735-1097(11)60524-X

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  • ASSESSMENT OF MORPHOLOGICAL FEATURES OF PLAQUES WITH ULTRASOUND ATTENUATION IN PATIENTS WITH ACUTE CORONARY SYNDROME USING OPTICAL COHERENCE TOMOGRAPHY

    Nobuhiko Maejima, Kiyoshi Hibi, Kenichiro Saka, Hiroyuki Suzuki, Zenkou Nagashima, Naoki Nakayama, Masayoshi Kiyokuni, Kozo Okada, Yasushi Matsuzawa, Masaaki Konishi, Katsutaka Hashiba, Mitsuaki Endo, Noriaki Iwahashi, Kengo Tsukahara, Yoshio Tahara, Masami Kosuge, Toshiaki Ebina, Satoshi Umemura, Kazuo Kimura

    JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY   57 ( 14 )   E1741 - E1741   2011.4

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    DOI： 10.1016/S0735-1097(11)61741-5

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  • LONG-TERM EFFECT OF EZETIMIBE-STATIN COMBINATION THERAPY ON LOW-DENSITY LIPOPROTEIN CHOLESTEROL LOWERING IN PATIENTS WITH CORONARY ARTERY DISEASE; FOCUS ON CHOLESTEROL ABSORPTION AND SYNTHESIS

    Kozo Okada, Kazuki Fukui, Hideo Himeno, Tutomu Endo, Makoto Shimizu, Shunichi Kobayashi, Tomohiko Shigemasa, Yukiko Morita, Atsushi Wada, Tomoaki Shimizu, Yasuyuki Mochida, Reimin Sawada, Tomoaki Ishigami, Kazuaki Uchino, Noriaki Iwahashi, Kazuo Kimura, Satoshi Umemura

    JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY   57 ( 14 )   E524 - E524   2011.4

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    DOI： 10.1016/S0735-1097(11)60524-X

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  • ASSESSMENT OF MORPHOLOGICAL FEATURES OF PLAQUES WITH ULTRASOUND ATTENUATION IN PATIENTS WITH ACUTE CORONARY SYNDROME USING OPTICAL COHERENCE TOMOGRAPHY

    Nobuhiko Maejima, Kiyoshi Hibi, Kenichiro Saka, Hiroyuki Suzuki, Zenkou Nagashima, Naoki Nakayama, Masayoshi Kiyokuni, Kozo Okada, Yasushi Matsuzawa, Masaaki Konishi, Katsutaka Hashiba, Mitsuaki Endo, Noriaki Iwahashi, Kengo Tsukahara, Yoshio Tahara, Masami Kosuge, Toshiaki Ebina, Satoshi Umemura, Kazuo Kimura

    JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY   57 ( 14 )   E1741 - E1741   2011.4

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    DOI： 10.1016/S0735-1097(11)61741-5

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  • Acute Myocardial Infarction Due to Aortic Dissection ; A Case Report of Coronary Malperfusion Caused by Hypotention Associated With Cardiac Tamponade

    TOMARI Sakie, SAITO Toshihiko, MINAMIMOTO Yugo, OKADA Kozo, ENDO Mitsuaki, NOZAWA Naoki, ENDO Tsutomu

    6 ( 1 )   87 - 94   2011.2

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  • Measuring the Baseline Cholesterol Absorption and Synthesis Marker Can Predict the LDL-C Lowering Response to Ezetimibe-Statin Combination Therapy in Patients with Coronary Artery Disease: A Multi-Center Prospective Randomized Trial

    Kozo Okada, Taku Fukuoka, Toshihiko Saitoh, Tutomu Endo, Kazuaki Uchino, Kazuaki Fukui, Shunichi Kobayashi, Makoto Shimizu, Yuji Iwasawa, Yukiko Morita, Atsushi Wada, Tomohiko Shigemasa, Yasuyuki Mochida, Noriaki Iwahashi, Satoshi Umemura, Kazuo Kimura

    CIRCULATION   122 ( 21 )   2010.11

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  • Measuring the Baseline Cholesterol Absorption and Synthesis Marker Can Predict the LDL-C Lowering Response to Ezetimibe-Statin Combination Therapy in Patients with Coronary Artery Disease: A Multi-Center Prospective Randomized Trial

    Kozo Okada, Taku Fukuoka, Toshihiko Saitoh, Tutomu Endo, Kazuaki Uchino, Kazuaki Fukui, Shunichi Kobayashi, Makoto Shimizu, Yuji Iwasawa, Yukiko Morita, Atsushi Wada, Tomohiko Shigemasa, Yasuyuki Mochida, Noriaki Iwahashi, Satoshi Umemura, Kazuo Kimura

    CIRCULATION   122 ( 21 )   2010.11

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Presentations

  • 地域包括心不全連携の構築に向けた取り組み Invited

    岡田興造

    2024年度疾患別医療介護連携事業 在宅医療連携拠点事業・南区在宅療養支援ネットワーク会  2025.1 

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  • 循環器領域における医科歯科 連携への期待 Invited

    岡田興造

    公益社団法人日本口腔インプラント学会 第44回関東・甲信越支部学術大会 メインシンポジウム  2025.2 

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  • 表情・音声バイオマーカーで 心不全診療の新たな未来を切り開く Invited

    岡田興造

    GTEI GAP DEMO DAY, Greater Tokyo Innovation Ecosystem  2025.5 

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  • LCA malperfusionに対するPCIのこつと限界

    岡田興造

    第9回大動脈解離シンポジウム  2023.6 

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  • 冠動脈疾患の早期発見・早期治療介入 - 冠動脈CTへの期待 -

    岡田興造

    市民公開講座（神奈川歯科大学附属横浜クリニック）  2023.5 

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  • 重症心筋梗塞の臨床的特徴と治療への展望

    岡田興造, 日比潔, 松澤泰志, 前島信彦, 岩橋徳明, 海老名俊明, 木村一雄

    第259回日本循環器学会関東甲信越地方会 特別企画: Clinical Research Awardセッション  2021.2 

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  • Underlying Mechanism of Neointimal Proliferation after Self-expanding Nitinol Stent Implantation: Insight from OFDI Analysis

    Okada K, Ikutomi M, Miki K, Fitzgerald PJ, Honda Y, Kawarada O

    Endovascular Asia 2018 Luncheon Seminar  2018.12 

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  • Attenuated-Signal Plaque and Long-Term Vessel Response After Bioresorbable Scaffold Implantation: IVUS Insights from the ABSORB JAPAN Trial

    Okada K, Honda Y, Kitahara H, Kameda R, Hollak MB, Yock PG, Kusano H, Cheong WF, Sudhir K, Kimura T

    Transcatheter Cardiovascular Therapeutics 2018  2018.9 

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  • Impact of myocardial bridging on long-term outcomes after heart transplantation: risk stratification with IVUS-determined anatomical properties

    Okada K, Nishi T, Tanaka S, Luikart H, Yock PG, Yeung AC, Fitzgerald PJ, Schnittger I, Khush KK, Fearon WF, Honda Y

    Transcatheter Cardiovascular Therapeutics 2019  2019.9 

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  • 急性冠症候群患者における腹部内臓脂肪の分布と冠動脈プラーク組織性状との関係

    岡田興造

    第29回日本心血管画像動態学会 特別企画: YIAセッション  2019.1 

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  • Bioresorbable Scaffold for Treatment of Coronary Artery Lesions: Final Intravascular Ultrasound Results from the ABSORB JAPAN Trial

    Okada K, Honda Y, Kitahara H, Ikutomi M, Kameda R, Hollak MB, Yock P, Kusano H, Cheong WF, Sudhir K, Fitzgerald PJ, Kimura T

    American College of Cardiology 67th Annual Scientific Session 2018  2018.3 

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  • Association Between Scaffold Under-Expansion and Late Lumen Loss after Bioresorbable Scaffold Implantation: IVUS and Angiographic Insights from the ABSORB Japan Trial

    Okada K, Honda Y, Kitahara H, Hollak MB, Yock PJ, Popma JJ, Kusano H, Cheong WF, Sudhir K, Fitzgerald PJ, Kimura T

    Transcatheter Cardiovascular Therapeutics 2017  2017.10 

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  • 冠動脈疾患二次予防の脂質管理戦略

    第47回京浜リピッドクラブ 特別講演  2018.6 

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  • 最近の知見からみた冠動脈疾患二次予防の脂質管理

    岡田興造

    第12回Trans-Catheter Imaging Forum ランチョンセミナー  2018.5 

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  • Physiology計測の注意点とiFRの可能性

    岡田興造

    TOkyo Percutaneous cardiovascular Intervention Conference 2021 特別企画: Sponsored Lecture  2021.7 

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  • 循環器疾患治療の課題と医科歯科連携への期待

    岡田興造

    歯科医師のための循環器特別セミナー  2021.5 

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  • INOCA概論 Invited

    岡田興造

    第273回日本循環器学会関東甲信越地方会 学術委員会企画セッション「非閉塞性冠動脈疾患（INOCA）診断の意義を考える」  2024.9 

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    Presentation type：Symposium, workshop panel (nominated)  

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  • Okada K, Kusu K, Kikuchi S, Etou H, Iguchi A, Onimura Y, Tsutsumi K, Hanajima Y, Kirigaya H, Nakahashi H, Matsushita K, Gohbara M, Sugano T, Seki Y, Hibi K

    Prognostic prediction of cardiovascular adverse events in patients after percutaneous coronary intervention using machine learning

    European Society of Cardiology Congress 2024  2024.9 

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  • DEMAND-HF Study:心不全における冠微小循環障害 Invited

    岡田興造

    第14回豊橋ライブデモンストレーションコース 臨床研究セッション 冠動脈疾患領域の未解決問題に挑む現在進行形の研究  2024.6 

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  • AIによるドライバーの心不全を予見する研究

    岡田興造

    国土交通省 第8回交通運輸技術フォーラム ～交通運輸分野の未来を切り開くスタートアップ～  2024.3 

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  • Strike Early, Strike Strong in Heart Failure Invited

    岡田興造

    第32回日本心血管インターベンション治療学会学術集会（CVIT2024）ランチョンセミナー32「心血管の連続性を考慮した治療戦略」  2024.7 

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  • The management of Impella Invited

    Kozo Okada

    2024.7 

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  • ARNI, Heart Failure and Beyond

    Kozo Okada

    第30回鎌倉ライブデモンストレーションコース Evening Seminar  2023.12 

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  • 健康寿命延伸を目指した高血圧・心不全治療

    岡田興造

    第36回日本冠疾患学会学術集会 ランチョンセミナー4  2023.11 

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  • 音声バイオマーカーを用いた新たな心不全診療構築への取り組み

    岡田興造

    第25回日本成人先天性心疾患学会 総会・学術集会 スイーツセミナー3  2024.1 

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  • 顔画像解析よる心不全増悪推定への試み

    岡田興造

    第27回日本心不全学会学術集会 シンポジウム7「心不全診療におけるAIの可能性」  2023.10 

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  • 高度石灰化病変の課題（Imagingモダリティからの課題）

    岡田興造

    TOPIC 2023（Industrial Symposia 2 新たな時代を迎える高度石灰化病変の治療戦略）  2023.7 

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  • ACSにおけるSpasmの診断・治療を再考する

    岡田興造

    第36回日本冠疾患学会学術集会 内科シンポジウム2  2023.11 

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  • Predicting Recurrence of Myocardial Infarction in Post-PCI Patients Using Machine Learning

    Okada K, Kusu K, Kikuchi S, Eto H, Sugano T, Seki Y, Hibi K

    American Heart Association Scientific Session 2023  2023.11 

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  • 血管内超音波の進むべき未来

    岡田興造

    第34回心血管画像動態学会 シンポジウム8「画像 血管内イメージング」  2024.1 

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  • ACSにおける冠攣縮を再考する

    岡田興造

    第34回心血管画像動態学会 シンポジウム5「INOCAを見逃すな」  2024.1 

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  • ACS二次予防における厳格な脂質管理の重要性

    岡田興造

    第34回心血管画像動態学会 ランチョンセミナー5  2024.1 

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  • 音声バイオマーカーを組み込んだ次世代型心不全管理

    岡田興造

    第34回心血管画像動態学会 日本心血管放射線研究会ジョイントセッション1「循環器疾患領域においてAIはどこまで進化したか」  2024.1 

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  • New avenues for heart failure treatment opened up by facial and vocal biomarkers Invited

    2024.10 

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  • 12誘導心電図画像のAI分析によるST上昇型心筋梗塞診断

    岡田興造, 濱上知樹, 後藤貴文, 神馬奈津子, 郷原正臣, 松下絢介, 小菅雅美, 海老名俊明, 菅野晃靖, 日比絜

    第72回日本心臓病学会学術集会 シンポジウム13「心血管画像診断におけるAIの現状」  2024.9 

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    Presentation type：Symposium, workshop panel (public)  

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  • What I learned from the review process: Culprit Lesion Morphology of Rapidly Progressive and Extensive Anterior-wall ST-segment Elevation Myocardial Infarction (RPEMI)

    Kozo Okada

    第87回日本循環器学会学術集会 Meet the Expert 4. Circulation: Cardiovascular Imaging: Editor's Picks for 2022  2023.3 

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  • Long-term Effect of Ezetimibe-plus-statin vs Double-dose Statin on Low-density Lipoprotein Cholesterol Lowering in Coronary Artery Disease Patients Pre-treated with a Statin; Focus on Cholesterol Absorption and Synthesis

    Okada K, Kimura K, Iwahashi N, Endo T, Himeno H, Fukui K, Kobayashi S, Shimizu M, Iwasawa Y, Morita Y, Wada A, Shigemasa T, Mochida Y, Shimizu T, Sawada R, Uchino K, Umemura S

    American Heart Association 84th Scientific Session 2011  2011.11 

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  • Long-Term Effect of Ezetimibe-Statin Combination Therapy on Low-density Lipoprotein Cholesterol Lowering in Patients with Coronary Artery Disease; Focus on Cholesterol Absorption and Synthesis

    Okada K, Fukui K, Himeno H, Endo T, Shimizu M, Kobayashi S, Shigemasa T, Morita Y, Wada A, Shimizu T, Mochida Y, Sawada R, Ishigami T, Uchino K, Iwahashi N, Kimura K, Umemura S

    American College of Cardiology 60th Annual Scientific Session 2011  2011.4 

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  • The Mechanism of Long-Term Low-density Lipoprotein Cholesterol Lowering Effect of Ezetimibe-Plus-Statin Combination Therapy in Coronary Artery Disease Patients; Comparison with Double-dose Statin Therapy

    Okada K, Kimura K, Iwahasi N, Endo T, Himeno H, Shimizu M, Wada A, Uchino K, Umemura S

    American College of Cardiology 61th Annual Scientific Session 2012  2012.3 

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  • Carriage of reduced-function CYP2C19 allele is an independent predictor of peri-procedural myocardial infarction in patients with acute coronary syndromes

    Okada K, Tsukahara K, Himeno H, Endo T, Fukui K, Hibi K, Sugano T, Kimura K, Umemura S

    American College of Cardiology 61th Annual Scientific Session 2012  2012.3 

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  • Measuring the Baseline Cholesterol Absorption and Synthesis Marker Can Predict the LDL-C Lowering Response to Ezetimibe-Statin Combination Therapy in Patients with Coronary Artery Disease: A Multicentr Prospective Randomized Trial

    Okada K, Fukuoka T, Saitoh T, Endo T, Uchino K, Fukui K, Kobayashi S, Shimizu M, Iwasawa Y, Morita Y, Wada A, Shigemasa T, Mochida Y, Iwahashi N, Umemura S, Kimura K

    American Heart Association 83th Scientific Session 2010  2010.11 

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  • Comparison of Bioresorbable Scaffold Measurements between Intravascular Ultrasound and Quantitative Coronary Angiography in the ABSORB Japan Trial

    Okada K, Honda Y, Kitahara H, Hollak MB, Yock PJ, Popma JJ, Kusano H, Cheong WF, Sudhir K, Fitzgerald PJ, Kimura T

    Transcatheter Cardiovascular Therapeutics 2017  2017.10 

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  • Final Optical Coherence Tomography Results from the COBRA PzF SHIELD Trial: Long–Term Arterial Response to A Novel Coronary Stent System with Nano-Thin Surface Coating for Pro-Endothelialization

    Okada K, Fitzgerald PJ, Cutlip DE, Barakat M, Silber S, Erglis A, Honda Y

    Euro PCR 2017  2017.5 

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  • Early Left Ventricular Dysfunction is Associated with Cardiac Allograft Vasculopathy and Late Mortality After Heart Transplantation

    Okada K, Honda Y, Luikart H, Yock PG, Fitzgerald PJ, Yeung AC, Valantine H, Khush KK, Fearon WF

    Transcatheter Cardiovascular Therapeutics 2016  2016.9 

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  • Endothelium Dependent and Independent Vasodilator Responses After Heart Transplantation: Geographic Distribution and Association with Progression of Cardiac Allograft Vasculopathy

    Okada K, Kimura T, Miki K, Yock P, Yeung A, Fitzgerald P, Luikart H, Khush K, Honda Y, Fearon WF

    American College of Cardiology 65th Annual Scientific Session 2016  2016.4 

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  • Early Invasive Assessment of the Coronary Microcirculation Predicts Subsequent Acute Rejection After Heart Transplantation

    Okada K, Honda Y, Luikart H, Yock PG, Fitzgerald PJ, Yeung AC, Valantine HA, Khush KK, Fearon WF

    American Heart Association 89th Scientific Session 2016  2016.11 

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  • Bioresorbable Vascular Scaffold for the Treatment of Tapered Coronary Lesions

    Okada K, Kitahara H, Yock P, Fitzgerald PJ, Kimura T, Honda Y

    Transcatheter Cardiovascular Therapeutics 2016  2016.9 

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  • Attenuated-Signal Plaque Progression Predicts Long-Term Mortality After Heart Transplantation

    Okada K, Kitahara H, Kimura T, Yock PG, Yeung AC, Fitzgerald PJ, Luikart H, Khush KK, Fearon WF, Honda Y

    American Heart Association 88th Scientific Session 2015  2015.11 

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  • Assessment of Bioresorbable Scaffold With a Novel High-Definition 60MHz IVUS Imaging System: Comparison With Conventional 40MHz IVUS and Optical Coherence Tomography

    Okada K, Kitahara H, Mitsutake Y, Tanaka S, Kimura T, Miki K, Yock PG, Fitzgerald PJ, Ikeno F, Honda Y

    Transcatheter Cardiovascular Therapeutics 2015  2015.10 

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  • Assessment of Bioresorbable Scaffold Struts With a Novel High-Definition 60MHz IVUS Imaging System: Comparison With 40MHz IVUS and Optical Coherence Tomography

    Okada K, Kitahara H, Mitsutake Y, Kimura T, Miki K, Ikeno F, Yock P, Fitzgerald P, Honda Y

    American College of Cardiology 65th Annual Scientific Session 2016  2016.4 

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  • Bioresorbable Scaffold for the Treatment of Lesions in Small Coronary Arteries: IVUS Insights from the ABSORB JAPAN Trial

    Okada K, Kitahara H, Otagiri K, Tanaka S, Kimura T, Yock P, Fitzgerald P, Kimura T, Honda Y

    American College of Cardiology 65th Annual Scientific Session 2016  2016.4 

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  • Bioresorbable Scaffold for the Treatment of Calcified Coronary Lesions: IVUS Insights from the ABSORB Japan Trial

    Okada K, Honda Y, Kitahara H, Hollak MB, Yock PJ, Kusano H, Cheong WF, Sudhir K, Fitzgerald PJ, Kimura T

    Transcatheter Cardiovascular Therapeutics 2017  2017.10 

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  • Paradoxical Arterial Remodeling of the Proximal Segment of the Left Anterior Descending Artery Predicts Long-Term Mortality after Heart Transplantation

    Okada K, Kitahara H, Yang HM, Tanaka S, Kobayashi Y, Luikart H, Yock P, Yeung A, Fitzgerald P, Khush KK, Honda Y, Fearon WF

    American College of Cardiology 64th Annual Scientific Session 2015  2015.3 

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  • Geographic Distribution of Cardiac Allograft Vasculopathy Associated with Acute Cellular Rejection: A Serial Three-Dimensional IVUS Study of Heart Transplant Recipients

    Okada K, Kitahara H, Yang HM, Lim HS, Otagiri K, Tanaka S, Kobayashi Y, Yock PG, Yeung AC, Fitzgerald PJ, Khush KK, Fearon WF, Honda Y

    American Heart Association 87th Scientific Session 2014  2014.11 

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  • Physiologic Assessment of Intermediate Coronary Artery Stenosis by Intravascular Ultrasound Radiofrequency Signal Analysis of Blood Speckles: A Comparison with Fractional Flow Reserve and Instantaneous Wave-Free Ratio

    Okada K, Hibi K, Matsushita K, Kitahara H, Fitzgerald PJ, Umemura S, Honda Y, Kimura K

    Transcatheter Cardiovascular Therapeutics 2015  2015.10 

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  • Attenuated-Signal Plaque and Cardiac Allograft Vasculopathy: A Serial Volumetric IVUS Study of Heart Transplant Recipients

    Okada K, Kitahara H, Otagiri K, Tanaka S, Kobayashi Y, Yock P, Yeung A, Fitzgerald P, Valantine HA, Khush KK, Fearon WF, Honda Y

    Transcatheter Cardiovascular Therapeutics 2014  2014.9 

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  • Association between abdominal fat distribution and coronary tissue characteristics in patients with acute coronary syndromes

    Okada K, Hibi K, Honda Y, Ebina T, Tsukahara K, Kosuge M, Tahara Y, Iwahashi N, Maejima N, Konishi M, Akiyama E, Takano K, Nakayama N, Gohbara M, Nagashima Z, Kataoka S, Suzuki H, Umemura S, Kimura K

    American College of Cardiology 63rd Annual Scientific Session 2014  2014.3 

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  • Coronary Artery Negative Remodeling and Intimal Thickening Predict Long-Term Clinical Outcomes after Heart Transplantation

    Okada K, Kitahara H, Yang HM, Lim HS, Otagiri K, Tanaka S, Kobayashi Y, Yock PG, Yeung AC, Fitzgerald PJ, Khush KK, Honda Y, Fearon WF

    American Heart Association 87th Scientific Session 2014  2014.11 

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  • Appropriate Intravascular Ultrasound Measurement Intervals for Assessment of Cardiac Allograft Vasculopathy after Heart Transplantation

    Okada K, Kitahara H, Otagiri K, Tanaka S, Kobayashi Y, Yock P, Yeung A, Fitzgerald PJ, Valantine HA, Khush KK, Fearon WF, Honda Y

    Transcatheter Cardiovascular Therapeutics 2014  2014.9 

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  • Glucose variability determined by continuous glucose monitoring system is more associated with poor clinical characteristics in ST-segment elevation myocardial infarction patients with type 2 diabetes mellitus and impaired glucose tolerance, in comparison with hemoglobin A1c levels

    Okada K, Gobara M, Iwahashi N, Nagashima Z, Suzuki H, Takano K, Akiyama E, Matsuzawa Y, Konishi M, Saka K, Maejima N, Endo M, Tsukahara K, Tahara Y, Hibi K, Kosuge M, Ebina T, Kimura K

    American Heart Association 85th Scientific Session 2012  2012.11 

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  • Association between Glycemic Variability and Coronary Tissue Characteristics in Patients with Acute Coronary Syndromes

    Okada K, Hibi K, Honda Y, Gohbara M, Kataoka S, Ebina T, Kosuge M, Tahara Y, Tsukahara K, Maejima N, Iwahashi N, Konishi M, Matsuzawa Y, Akiyama E, Nakayama Z, Suzuki H, Umemura S, Kimura K

    Transcatheter Cardiovascular Therapeutics 2013  2013.11 

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  • Association between higher glucose variability, determined by continuous glucose monitoring system, and poor clinical characteristics in ST-segment elevation myocardial infarction (STEMI) patients with dysglycemia in comparison with conventional glycemic parameters

    Okada K, Kataoka S, Gohbara M, Suzuki H, Nagashima Z, Takano K, Akiyama E, Matsuzawa Y, Konishi M, Maejima N, Endo M, Iwahashi N, Tsukahara K, Tahara Y, Saka K, Hibi K, Kosuge M, Ebina T, Umemura S, Kimura K

    American College of Cardiology 62th Annual Scientific Session 2013  2013.3 

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  • Clinical Utility Of Machine Learning-derived Vocal-biomarker In The Management Of Heart Failure

    Okada K, Omiya Y, Mizuguchi D, Endo K, Kobayashi Y, Matsuzawa Y, Iwahashi N, Kosuge M, Ebina T, Tamura K, Hibi K

    American Heart Association Scientific Session 2022  2022.11 

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  • 心不全管理における音声バイオマーカーの利用可能性に関する検討

    岡田興造

    第26回日本心不全学会学術集会 パネルディスカッション4. 心不全診療・治療におけるAIの有用性  2022.10 

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  • AI-based next-generation heart failure management system using vocal biomarker

    岡田興造

    第87回日本循環器学会学術集会 Symposium 2. AIが変える循環器領域/Transformation of Field of Circulation by Artificial Intelligence  2023.3 

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  • 冠動脈プラークに着目したACC再発予防における脂質管理治療戦略

    岡田興造

    第33回日本心血管画像動態学会 コーヒーブレークセミナー8. ACS二次予防における積極的脂質低下療法の意義  2023.1 

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  • 心筋梗塞を未然に防ぐためには -医科歯科連携への期待

    岡田興造

    市民公開講座（神奈川歯科大学附属横浜クリニック）  2021.11 

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  • ACS治療の現状と課題

    岡田興造

    第261回日本循環器学会関東甲信越地方会 学術委員会セッション：急性冠症候群に対する治療戦略を再考する  2021.9 

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  • Culprit Lesion Morphology of Rapidly Progressive and Extensive Anterior-wall ST-segment Elevation Myocardial Infarction

    Okada K, Hibi K, Kimura K

    K-IMAGING 2022 Korea Cardiovascular Interventional Imaging Forum  2022.6 

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  • ACSの再発予防における脂質管理

    第59回日本心血管インターベンション治療学会関東甲信越地方会 ショートレクチャー6  2022.5 

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  • 顔と声の特徴量を使って心不全入院を防ぎ、健康寿命を延ばす Invited

    岡田興造

    GTIE、MASP、Tongali が支援するライフサイエンス研究者による DEMODAY  2025.2 

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Industrial property rights

  • 情報処理装置、情報処理方法、情報処理システム、及び情報処理プログラム

    岡田興造, 小林雄祐, 遠藤弘司, 大宮康宏, 高野毅

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    Application no：特願2022-545955  Date applied：2022.6

    Patent/Registration no：特許第7246664号  Date registered：2023.3 

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  • 心不全推定装置、心不全推定システム、心不全 推定方法、及び心不全推定プログラム

    岡田興造, 石原啓一郎, 小林雄祐

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    Applicant：公立大学法人横浜市立大学

    Application no：特願2024-576488  Date applied：2022.2

    Patent/Registration no：特許第7672033号  Date registered：2025.4 

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Awards

  • 令和6年度 病院長表彰

    2025   公立大学法人横浜市立大学附属市民総合医療センター  

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  • 心血管画像診断学賞：Cardiovascular Imaging Award（吉川純一賞）

    2024   日本心血管画像動態学会  

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  • 令和4年理事長・学長表彰 教員部門「奨励賞」

    2023   公立大学法人横浜市立大学  

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  • Clinical Research Award the First Prize

    2021   The 259th Japanese Circulation Society Kantokoshinetsu Regional Meeting  

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  • Young Investigator Award 2019 the First Prize

    2019   The 29th Japanese Society of Cardiovascular Imaging & Dynamics  

    OKADA Kozo

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  • Strategy and Treatment For Cardiovascular Disease Award 2017

    2017  

    OKADA Kozo

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  • 28th Transcatheter Cardiovascular Therapeutics Top 50 Abstract Award 2016

    2016   Transcatheter Cardiovascular Therapeutics  

    OKADA Kozo

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  • Cardiovascular Institute Manuscript Award 2016

    2016   Stanford University  

    OKADA Kozo

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  • 27th Transcatheter Cardiovascular Therapeutics Top 50 Abstract Award 2015

    2015   Transcatheter Cardiovascular Therapeutics  

    OKADA Kozo

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  • Cardiovascular Institute Travel Award 2015

    2015   Stanford University  

    OKADA Kozo

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  • Cardiovascular Institute Travel Award 2014

    2014   Stanford University  

    OKADA Kozo

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  • Stanford Cardiovascular Research Scholarship Program, 2013

    2013  

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  • Best Presenter

    2011   首都心臓病カンファレンス  

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Research Projects

  • 人間とAGIの共生と死生観―人間の尊厳を守るELSI構想のために

    2025.10 - 2027.9

    公益財団法人 村田学術振興・教育財団  第41回（2025年度） 公益財団法人 村田学術振興・教育財団 

    松本郁代, 土屋隆裕, 岡田興造

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  • 心不全予測を行う表情・音声の新規バイオマーカーに関する開発研究

    Grant number：24017082  2024.5 - 2025.3

    AMED: 国立研究開発法人日本医療研究開発機構  医療機器等研究成果展開事業 令和６年度 医療機器等研究成果展開事業 チャレンジタイプ 

    岡田興造

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  • 高血圧・高血圧性臓器障害における血管新生因子の病態生理学的意義

    Grant number：24K10557  2024.4 - 2027.3

    日本学術振興会  科学研究費助成事業  基盤研究(C)

    金岡知彦, 岡田興造, 涌井広道

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    Authorship：Coinvestigator(s) 

    Grant amount：\4550000 （ Direct Cost: \3500000 、 Indirect Cost：\1050000 ）

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  • 表情と音声の機械学習モデルを使った心不全予測を行う新規バイオマーカーの研究開発

    2024.4 - 2025.3

    Greater Tokyo Innovation Ecosystem(GTIE)(3) 

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    Authorship：Principal investigator 

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  • 表情と音声の機械学習モデルを使った心不全予測を行う新規バイオマーカーの研究開発

    2024 - 2026

    公立大学法人 横浜市立大学  学長裁量事業 第6期 戦略的研究推進事業 

    岡田興造

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  • AIによるドライバーの心不全を予見する研究

    2023.11 - 2024.3

    国土交通省  令和5年度交通運輸技術開発推進制度（短期集中型） 

    岡田興造

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  • ST上昇型心筋梗塞のAI心電図診断アルゴリズム構築に関する研究

    2023.6 - 2024.5

    公益財団法人 福田記念医療技術振興財団  第34回(2023年度)研究助成事業 

    岡田興造

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  • 非虚血性心不全症例の、冠微小循環障害の合併頻度およびその機序を解明する研究

    Grant number：23K07483  2023.4 - 2027.3

    日本学術振興会  科学研究費助成事業  基盤研究(C)

    日比潔, 梅村将就, 畠山金太, 岡田興造

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    Grant amount：\4810000 （ Direct Cost: \3700000 、 Indirect Cost：\1110000 ）

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  • 多機関共同のリアルワールドデータ研究に対するrisk based approachを用いた臨床研究支援の実装と課題解決法の提案

    Grant number：22723796  2022.10 - 2023.3

    国立研究開発法人 日本医療研究開発機構（AMED）  研究開発推進ネットワーク事業 RBAの実装に向けた整備、方策等の提案及び推進

    田野島玲大, 熊谷雄治, 矢野裕一朗, 清水沙友里, ⾦⼦惇, 前⽥愼, 宮城悦子, ⼩林雄祐, 須江聡⼀郎, ⾼瀬創, 仁⽥学, ⼟師達也, 野﨑昭⼈, 岡田興造, 稲垣尚⼦

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    Authorship：Coinvestigator(s) 

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  • 冠動脈疾患を合併しない心不全における冠微小循環障害に関する前向きコホート研究

    2022.8 - 2023.3

    横浜市立大学市民総合医療センター  センター病院 遺贈活用研究推進事業「浦舟 がん･ハートプロジェクト」 

    岡田興造, 日比潔

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  • 表情画像と音声情報のAI分析による心不全増悪予測システムに関する研究開発

    2022.6 - 2023.5

    公益財団法人 村田学術振興財団  令和4年度 研究助成 

    岡田興造

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  • 住民参加型地域コミュニティ拠点モデルの構築～繋がりの力で健幸と省エネを実現するウェルビーイングエコタウン共創拠点形成に向けて～

    2022 - 2023

    横浜市立大学  第4期 学術的研究推進事業「YCU未来共創プロジェクト2022年度」 

    土肥眞奈, 石川義弘, 叶谷由佳, 鈴木伸治, 齊藤広子, 三輪律江, 秋元康幸, 金子惇, 日比潔, 岡田興造

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    Authorship：Coinvestigator(s) 

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  • 表情画像と音声情報のAI分析による心不全増悪予測モデルの開発

    2021.6 - 2022.3

    公益財団法人 木原記念横浜生命科学振興財団  2021年度LIP. 横浜 トライアル助成金 

    岡田興造

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  • Effect of intensified multifactorial intervention on coronary atherosclerosis in patients with coronary artery disease and type 2 diabetes (IMPACT-DM)

    Grant number：21K08132  2021.4 - 2025.3

    Japan Society for the Promotion of Science  Grants-in-Aid for Scientific Research  Grant-in-Aid for Scientific Research (C)

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    Authorship：Principal investigator 

    Grant amount：\4160000 （ Direct Cost: \3200000 、 Indirect Cost：\960000 ）

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