Updated on 2026/01/10

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写真a

 
Teppei Nishii
 
Organization
School of Medicine Medical Course Medical informatics Lecturer
Title
Lecturer
Profile

いつまでも学ぶ姿勢を失わず、自らが学んだことを地域に還元する医療を目指します。

External link

Degree

  • 博士(医学) ( 横浜市立大学 )

Research Interests

  • 医療情報学

  • 医療の質・安全管理学

Research Areas

  • Informatics / Life, health and medical informatics

Papers

  • A two-stage reconstruction for aortoesophageal fistula after replacement of thoracic aorta for Stanford Type B dissecting aortic aneurysm: esophagectomy and a double-tract reconstruction using the pedicled jejunum: a case report and literature review.

    Sho Sato, Chikara Kunisaki, Yusaku Tanaka, Kei Sato, Hiroshi Miyamoto, Norio Yukawa, Hiroko Nemoto, Keiji Uchida, Teppei Nishii, Takashi Kosaka, Hirotoshi Akiyama, Itaru Endo

    Clinical journal of gastroenterology   13 ( 5 )   722 - 727   2020.10

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    An aortoesophageal fistula (AEF) is a rare, potentially fatal condition, and esophagectomy is usually performed simultaneously with aortic surgery. However, esophageal reconstruction method has not been established. This case report describes a two-stage operation for AEF after replacement of thoracic aorta for Stanford Type B dissecting aortic aneurysm. A 61-year-old man who had underwent total arch replacement with frozen elephant trunk for Stanford Type B dissecting aortic aneurysm 3 years ago admitted to the hospital with high fever. Based on the computed tomography and endoscopic findings, he was diagnosed with having aortoesophageal fistula (AEF). After administration of antibiotics with fasting foods and drinks for a month, he underwent the second aortic replacement, thoracic esophagectomy, cervical esophagostomy, gastrostomy and omental wrapping. After 3 months, he underwent double-tract reconstruction using the pedicled jejunal transfer with supercharge and superdrainage via the subcutaneous route. After reconstruction surgery, the patient was doing well. Two-stage reconstruction was a safe procedure for AEF case who underwent aortic replacement, esophagectomy and omental wrapping. The pedicled jejunum reconstruction via subcutaneous route is an optional procedure for second reconstruction surgery.

    DOI： 10.1007/s12328-020-01158-9

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  • 肺癌術後第2癌(異時性多発肺癌および肺内転移)の外科的管理におけるACCPガイドラインの有用性

    石川 善啓, 禹 哲漢, 奥寺 康司, 荒井 宏雅, 田尻 道彦, 安藤 耕平, 諸星 隆夫, 津浦 幸夫, 西井 鉄平, 伊坂 哲哉, 利野 靖, 益田 宗孝

    日本外科学会定期学術集会抄録集   120回   DP - 7   2020.8

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  • 肺癌術後孤立性充実性結節(異時性多発肺癌および肺内転移)切除例の長期成績

    石川 善啓, 伊坂 哲哉, 菊池 章友, 益田 宗孝, 荒井 宏雅, 田尻 道彦, 安藤 耕平, 諸星 隆夫, 西井 鉄平, 禹 哲漢

    日本呼吸器外科学会雑誌   34 ( 3 )   O3 - 5   2020.8

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  • A prophylaxis study of acute exacerbation of interstitial pneumonia after lung cancer surgery. International journal

    Hiroyuki Ito, Haruhiko Nakayama, Tomoyuki Yokose, Takuya Nagashima, Takao Morohoshi, Michihiko Tajiri, Takamitsu Maehara, Katsuya Watanabe, Hiromasa Arai, Taketsugu Yamamoto, Tekkan Woo, Teppei Nishii, Yoshihiro Ishikawa, Satoshi Morita, Munetaka Masuda

    Japanese journal of clinical oncology   50 ( 2 )   198 - 205   2020.2

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    INTRODUCTION: Acute exacerbation of interstitial pneumonia (AE-IP) is a lethal complication after lung surgery. We conducted a prospective, multi-institutional phase II trial to assess the efficacy and safety of prophylactic measures. METHOD: Patients with lung cancer with dorsal subpleural fibrotic changes occupying three or more segments of both lower lobes and planned anatomical lung resection were enrolled. Prior to surgery, patients received a 125-mg bolus injection of methylprednisolone and continuous intravenous infusion of sivelestat sodium hydrate (sivelestat) for 2 days. RESULTS: Sixty-nine patients were analysed. Preoperative high-resolution computed tomography (HRCT) showed 37 (53.6%) cases presented with usual interstitial pneumonia (UIP) and possible UIP pattern. There were 60 lobectomies and 9 segmentectomies. Thirty-eight cases were in clinical stage I. No adverse events associated with prophylaxis were observed. There were four cases of AE-IP (5.8%), higher than the expected 2.0%. Three of the four cases showed inconsistencies with the UIP pattern in preoperative HRCT and were pathologically diagnosed as UIP. All patients died of respiratory failure. Overall, 89.9% were diagnosed as idiopathic interstitial pneumonias; UIP was found in 48 patients (69.6%). Severe post-operative complications occurred in 11.6% of the cases. There were 35 deaths, 17 cases of lung cancer and 11 cases related to interstitial pneumonias. The overall survival rate at 3 years was 41.8% of the total and 47.2% of cases with clinical stage I. CONCLUSIONS: Perioperative use of sivelestat and low-dose methylprednisolone in patients with anatomical lung resection was safe but did not prove to be a prophylactic effect for AE-IP.

    DOI： 10.1093/jjco/hyz164

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  • Retrospective study of efficacy of adjuvant chemotherapy using tegafur-uracil in patients with non-small cell lung cancer with primary tumor size of 4.1-5.0 cm. Reviewed International journal

    Adachi H, Nishii T, Yamamoto T, Nagashima T, Ishikawa Y, Ando K, Woo T, Maehara T, Nakayama H, Masuda M

    Journal of thoracic disease   11 ( 7 )   3103 - 3111   2019.7

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    Background: The staging of patients with a tumor of diameter 4.1-5.0 cm and no lymphatic/distant metastases have been up-graded to stage IIA in the latest 8th edition of the TNM staging system. However, the efficacy of adjuvant tegafur-uracil (UFT) therapy in these patients, which has been recommended in the guideline issued by The Japan Lung Cancer Society, remains unclear. We evaluated the efficacy of adjuvant UFT therapy among a cohort by retrospective analyses of multicentric database. Methods: In 2005-2007, 130 patients with p-stage IB non-small cell lung cancer (NSCLC) (diagnosed according to the 7th edition of the TNM staging system) and tumor size of ≥3.1 cm underwent anatomic complete resection at nine of our affiliated hospitals. We retrospectively reviewed the clinicopathological characteristics and the outcomes among these patients. Results: Ninety-eight patients had tumor size of 3.1-4.0 cm (T2a group), whereas 32 patients had tumor size >4.0 cm (T2b group). Overall, patients who received adjuvant UFT showed a tendency of better outcomes than patients who did not [hazard ratio (HR) 0.564; 95% confidence interval (CI), 0.257-1.238, P=0.147]. In subgroup analyses, patients who received adjuvant UFT also tended to show better outcomes than those who did not in both T2a group and T2b group (HR 0.504; 95% CI, 0.202-1.255, P=0.132 in T2a group and HR 0.855; 95% CI, 0.181-4.033, P=0.843 in T2b group, respectively). Conclusions: Our results suggest that adjuvant UFT therapy have the potential to improve postoperative outcomes even in patients with p-stage IIA disease, as classified according to the 8th edition of the TNM staging system.

    DOI： 10.21037/jtd.2019.07.05

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  • 多発肺癌・異時性第二肺癌、再発肺癌の治療戦略 肺癌術後第2癌(異時性多発肺癌および肺内転移)切除例の臨床病理学的背景と長期予後の検討

    石川 善啓, 伊坂 哲哉, 禹 哲漢, 益田 宗孝, 荒井 宏雅, 田尻 道彦, 安藤 耕平, 諸星 隆夫, 西井 鉄平, 乾 健二

    日本呼吸器外科学会雑誌   33 ( 3 )   WS1 - 4   2019.4

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  • シベレスタットを用いた肺癌術後間質性肺炎急性増悪予防策の効果(YCTS1201;SHIP trial)

    伊藤 宏之, 中山 治彦, 永島 琢也, 鮫島 譲司, 諸星 隆夫, 前原 孝光, 田尻 道彦, 渡部 克也, 荒井 宏雅, 山本 健嗣, 大森 隆広, 禹 哲漢, 西井 鉄平, 石川 善啓, 安藤 耕平, 足立 広幸, 伊坂 哲哉, 乾 健二, 森田 智視, 益田 宗孝

    肺癌   58 ( 6 )   526 - 526   2018.10

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  • Gender Differences in the Recurrence Timing of Patients Undergoing Resection for Non-Small Cell Lung Cancer Reviewed International journal

    Katsuya Watanabe, Kentaro Sakamaki, Teppei Nishii, Taketsugu Yamamoto, Takamitsu Maehara, Haruhiko Nakayama, Munetaka Masuda

    Asian Pacific journal of cancer prevention : APJCP   19 ( 3 )   719 - 724   2018.3

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    Objective: This study was designed to visually represent postoperative recurrence patterns using event dynamics
    and to assess sex-based differences in the timing of recurrence for non-small cell lung cancer. Methods: We studied
    829 patients (538 men, 291 women) with NSCLC who underwent complete pulmonary resection in 9 hospitals. Event
    dynamics with the use of life-table methods were evaluated, and only first events (distant metastases or local recurrence)
    were considered. The effects of sex, histological type, pathological stage, and smoking history were studied. Result:
    The resulting smoothed hazard rate curves indicated that the recurrence risk pattern definitely correlated with sex, with
    a sharp peak in the first year in men and a broad peak during the first 2 to 3 years in women. These findings were also
    confirmed by analyses according to pathological stage, histological type, and smoking history. Conclusion: The peak
    times of recurrence differed considerably between men and women. The delayed time of peak recurrence in women,
    associated with a longer disease-free interval within subsets of patients with similar disease stage, histological type,
    and smoking status, might account for the better survival in women.

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  • Detection of tumor spread through airspaces by airway secretion cytology from resected lung cancer specimens Reviewed

    Tetsuya Isaka, Tomoyuki Yokose, Yohei Miyagi, Kota Washimi, Teppei Nishii, Hiroyuki Ito, Haruhiko Nakayama, Kouzo Yamada, Munetaka Masuda

    PATHOLOGY INTERNATIONAL   67 ( 10 )   487 - 494   2017.10

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    DOI： 10.1111/pin.12570

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  • Prognostic value of EGFR mutations in surgically resected pathological stage I lung adenocarcinoma Reviewed

    Teppei Nishii, Tomoyuki Yokose, Yohei Miyagi, Yataro Daigo, Tetsuya Isaka, Hideyuki Furumoto, Hiroyuki Ito, Shuji Murakami, Tetsuro Kondo, Haruhiro Saito, Fumihiro Oshita, Kouzo Yamada, Shoichi Matsukuma, Haruhiko Nakayama, Munetaka Masuda

    ASIA-PACIFIC JOURNAL OF CLINICAL ONCOLOGY   13 ( 5 )   E204 - E211   2017.10

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    DOI： 10.1111/ajco.12512

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  • 腫瘍径4〜5cm症例の術後補助化学療法はUFTでよいか? p-T2aN0M0(第7版)症例の後方視的検討

    足立 広幸, 西井 鉄平, 山本 健嗣, 永島 琢也, 安藤 耕平, 石川 善啓, 禹 哲漢, 渡部 克也, 熊切 寛, 坪井 正博, 前原 孝光, 中山 治彦, 益田 宗孝

    肺癌   57 ( 5 )   465 - 465   2017.9

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  • Body mass index, C-reactive protein and survival in smokers undergoing lobectomy for lung cancer Reviewed

    Masashi Nagata, Hiroyuki Ito, Tomohiko Matsuzaki, Hideyuki Furumoto, Tetsuya Isaka, Teppei Nishii, Tomoyuki Yokose, Haruhiko Nakayama

    EUROPEAN JOURNAL OF CARDIO-THORACIC SURGERY   51 ( 6 )   1164 - 1170   2017.6

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    DOI： 10.1093/ejcts/ezx004

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  • Carcinoma Showing Thymus-like Differentiation(CASTLE)の縦隔再発の1例 Reviewed

    鮫島 譲司, 伊藤 宏之, 中山 治彦, 西井 鉄平, 大澤 潤一郎, 橋本 昌憲, 和田 篤史, 鈴木 理樹, 横瀬 智之, 益田 宗孝

    肺癌   57 ( 1 )   52 - 52   2017.2

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  • Lobe-Specific Lymph Node Dissection as a Standard Procedure in Surgery for Non-Small Cell Lung Cancer: A Propensity Score Matching Study. Reviewed International journal

    Hiroyuki Adachi, Kentaro Sakamaki, Teppei Nishii, Taketsugu Yamamoto, Takuya Nagashima, Yoshihiro Ishikawa, Kohei Ando, Kazuki Yamanaka, Katsuya Watanabe, Yutaka Kumakiri, Masahiro Tsuboi, Takamitsu Maehara, Haruhiko Nakayama, Munetaka Masuda

    Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer   12 ( 1 )   85 - 93   2017.1

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    INTRODUCTION: Systematic lymph node dissection (SND) is the standard procedure in surgical treatment for NSCLC, but the value of this approach for survival and nodal staging is still uncertain. In this study, we evaluated the potential of lobe-specific lymph node dissection (L-SND) in surgery for NSCLC by using a propensity score matching method. METHODS: From 2005 to 2007, 565 patients with cT1a-2b N0-1 M0 NSCLC underwent lobectomy with lymph node dissection at our 10 affiliated hospitals. Patients were classified into groups that underwent nodal sampling, L-SND, and systematic dissection SND on the basis of pathological data for the number and extent of nodal resection. A total of 77 patients with insufficient pathological data were excluded from the study. RESULTS: Overall, survival did not differ significantly among the groups (p = 0.552), but the rate of detection of pN2 in the SND group (13.1%) was significantly higher than in the nodal sampling (3.3%) and L-SND (9.0%) groups (p = 0.010). However, given the many confounding factors in the patient characteristics in each group, outcomes were reevaluated using a propensity score matching method for the L-SND and SND groups. After matching, the two groups had no significant differences in 5-year overall survival (73.5% for L-SND versus 75.3% for SND, p = 0.977) and pN2 detection (8.2% in both groups, p = 0.779). CONCLUSIONS: These results suggest that lobe-specific lymph node dissection has the potential to be a standard procedure in surgical treatment for NSCLC.

    DOI： 10.1016/j.jtho.2016.08.127

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  • Alveolar soft-part sarcoma of the mediastinum: A case report. Reviewed

    Kameda Y, Nishii T, Tsuboi M, Arai H, Inui K, Kaneko T, Kimura N, Naruse M, Masuda M

    SAGE open medical case reports   5   2050313X17695473   2017

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  • Feasibility and efficacy of salvage lung resection after definitive chemoradiation therapy for Stage III non-small-cell lung cancer Reviewed

    Yoshihisa Shimada, Kenji Suzuki, Morihito Okada, Haruhiko Nakayama, Hiroyuki Ito, Tetsuya Mitsudomi, Hisashi Saji, Kazuya Takamochi, Yujin Kudo, Aritoshi Hattori, Takahiro Mimae, Keiju Aokage, Teppei Nishii, Masahiro Tsuboi, Norihiko Ikeda

    INTERACTIVE CARDIOVASCULAR AND THORACIC SURGERY   23 ( 6 )   895 - 901   2016.12

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  • Epidermal Growth Factor Receptor Mutations and Prognosis in Pathologic N1-N2 Pulmonary Adenocarcinoma Reviewed

    Tetsuya Isaka, Haruhiko Nakayama, Tomoyuki Yokose, Hiroyuki Ito, Yohei Miyagi, Tomohiko Matsuzaki, Masashi Nagata, Hideyuki Furumoto, Teppei Nishii, Kayoko Katayama, Kouzo Yamada, Munetaka Masuda

    ANNALS OF THORACIC SURGERY   102 ( 6 )   1821 - 1828   2016.12

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    DOI： 10.1016/j.athoracsur.2016.06.001

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  • T3a症例に対する胸腔鏡下手術の妥当性の検討

    安藤 耕平, 諸星 隆夫, 稲福 賢司, 増田 晴彦, 足立 広幸, 永島 琢也, 西井 鉄平, 高橋 航, 山本 健嗣, 山仲 一輝, 渡部 克也, 熊切 寛, 益田 宗孝

    肺癌   56 ( 6 )   775 - 775   2016.11

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  • Postoperative follow-up strategy based on recurrence dynamics for non-small-cell lung cancer. Reviewed International journal

    Katsuya Watanabe, Masahiro Tsuboi, Kentaro Sakamaki, Teppei Nishii, Taketsugu Yamamoto, Takuya Nagashima, Kohei Ando, Yoshihiro Ishikawa, Tekkan Woo, Hiroyuki Adachi, Yutaka Kumakiri, Takamitsu Maehara, Haruhiko Nakayama, Munetaka Masuda

    European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery   49 ( 6 )   1624 - 31   2016.6

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    OBJECTIVES: Our study was designed to visually represent recurrence patterns after surgery for non-small-cell lung cancer (NSCLC) with the use of event dynamics and to clarify postoperative follow-up methods based on the times of recurrence. METHODS: A total of 829 patients with NSCLC who underwent complete pulmonary resection from 2005 to 2007 in 9 hospitals affiliated with the Yokohama Consortium of Thoracic Surgeons were studied. Event dynamics, based on the hazard rate, were evaluated. Only first events involving the development of distant metastases, local recurrence or both were considered. The effects of sex, histological type, pathological stage and age were studied. RESULTS: The hazard rate curve displayed an initial surge that peaked about 6-8 months after surgery. The next distinct peak was noted at the end of the second year of follow-up. On non-parametric kernel smoothing, the maximum peak was found 6-8 months after surgery in men. In women, the highest peak occurred 22-24 months after surgery, which was about 16 months later than the peak in men. The peak timing of the hazard curve was not affected by histological type, pathological stage or age in either sex. CONCLUSIONS: Our results suggest that the timing of recurrence after surgery for lung cancer is characterized by a bimodal pattern, and the times with the highest risk of recurrence were suggested to differ between men and women. Postoperative follow-up strategies should be based on currently recommended follow-up programmes, take into account the recurrence patterns of lung cancer, and be modified as required to meet the needs of individual patients.

    DOI： 10.1093/ejcts/ezv462

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  • 原発性肺癌における再発時期を考慮した術後経過観察法

    渡部 克也, 椎野 王久, 足立 広幸, 石川 善啓, 安藤 耕平, 永島 琢也, 西井 鉄平, 山本 健嗣, 山仲 一輝, 熊切 寛, 坪井 正博, 益田 宗孝

    日本呼吸器外科学会雑誌   30 ( 3 )   P18 - 5   2016.4

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  • Prediction of lung tumor palpability using high-resolution computed tomography Reviewed

    Tetsuya Isaka, Hiroyuki Ito, Tomoyuki Yokose, Tetsuro Kondo, Masashi Nagata, Teppei Nishii, Kouzo Yamada, Haruhiko Nakayama, Munetaka Masuda

    Asian Cardiovascular and Thoracic Annals   24 ( 1 )   23 - 29   2016.1

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    DOI： 10.1177/0218492315615480

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  • Influence of visceral pleural invasion on survival in completely resected non-small-cell lung cancer Reviewed International journal

    Adachi H, Tsuboi M, Nishii T, Yamamoto T, Nagashima T, Ando K, Ishikawa Y, Woo T, Watanabe K, Kumakiri Y, Maehara T, Morohoshi T, Nakayama H, Masuda M

    Eur J Cardiothorac Surg   48 ( 5 )   691 - 697   2015.11

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    OBJECTIVES: Although the prognostic implications of visceral pleural invasion (VPI) are well established, it remains controversial whether the extent of VPI affects survival in patients with completely resected non-small-cell lung cancer (NSCLC). In addition, the impact of VPI according to nodal status is unclear. We evaluated the influence of the extent of pleural invasion on survival by analysing a multicentre retrospective database of patients who had undergone surgery for NSCLC. METHODS: We retrospectively reviewed the clinicopathological characteristics and outcomes of 639 patients with NSCLC who underwent anatomic complete resection from 2005 to 2007 at nine hospitals affiliated with the Yokohama Consortium of Thoracic Surgeons. RESULTS: The median follow-up was 65.0 months. The extent of pleural invasion was PL0 in 462 patients, PL1 in 135 and PL2 in 42. The 5-year overall survival rate was significantly higher in patients with PL0 tumours (75.9%) than in those with PL1 (63.6%) or PL2 tumours (54.1%). On subgroup analysis according to nodal status, PL0 was associated with a higher survival rate than that of PL1 or PL2 tumours in patients with N0 or N1 metastasis, but not in those with N2 metastasis. There was no difference between PL1 and PL2 in any subgroup. CONCLUSIONS: Our results suggest that the presence of VPI, rather than the extent, has an impact on postoperative survival in patients with NSCLC who have N0 or N1 metastasis. Because very few previous studies have addressed the effects of VPI in patients with N1 disease, further re-evaluation of the prognostic impact of VPI is necessary in this subgroup of patients.

    DOI： 10.1093/ejcts/ezu515

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  • Diagnosis of metachronous multiple lung adenocarcinoma at the cut-end by epidermal growth factor receptor mutation status discordance 4 years after sublobar resection for adenocarcinoma in situ: report of a case Reviewed

    Tetsuya Isaka, Tomoyuki Yokose, Hiroyuki Ito, Naoko Imamura, Masato Watanabe, Kentaro Imai, Teppei Nishii, Kouzo Yamada, Haruhiko Nakayama, Munetaka Masuda

    SURGERY TODAY   45 ( 10 )   1330 - 1334   2015.10

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    DOI： 10.1007/s00595-014-1077-z

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  • 原発性肺癌の再発時期を考慮した術後経過観察法

    渡部 克也, 三ツ堀 隼弘, 足立 広幸, 石川 善啓, 安藤 耕平, 永島 琢也, 西井 鉄平, 山本 健嗣, 山仲 一輝, 熊切 寛, 坪井 正博, 益田 宗孝

    肺癌   55 ( 5 )   453 - 453   2015.10

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  • Correlations Between the EGFR Mutation Status and Clinicopathological Features of Clinical Stage I Lung Adenocarcinoma Reviewed

    Tetsuya Isaka, Tomoyuki Yokose, Hiroyuki Ito, Masashi Nagata, Hideyuki Furumoto, Teppei Nishii, Kayoko Katayama, Kouzo Yamada, Haruhiko Nakayama, Munetaka Masuda

    MEDICINE   94 ( 42 )   2015.10

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    DOI： 10.1097/MD.0000000000001784

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  • 肺癌取扱い規約第7版におけるp-stage IA肺癌術後の予後不良因子の検討

    足立 広幸, 西井 鉄平, 山本 健嗣, 永島 琢也, 安藤 耕平, 石川 善啓, 山仲 一輝, 渡部 克也, 熊切 寛, 坪井 正博, 益田 宗孝

    肺癌   55 ( 5 )   495 - 495   2015.10

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  • 原発性肺癌の術後再発時期の検討

    渡部 克也, 三ツ堀 隼弘, 足立 広幸, 石川 善啓, 安藤 耕平, 永島 琢也, 西井 鉄平, 山本 健嗣, 山仲 一輝, 熊切 寛, 坪井 正博, 益田 宗孝

    日本呼吸器外科学会雑誌   29 ( 3 )   O10 - 4   2015.4

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  • 臨床病期cT1b/T2aN0肺癌に対する肺葉切除症例の縦隔リンパ節郭清範囲の検討

    石川 善啓, 橋本 昌憲, 永島 琢也, 安藤 耕平, 荒井 宏雅, 足立 広幸, 西井 鉄平, 渡部 克也, 山本 健嗣, 山仲 一輝, 熊切 寛, 五来 厚生, 益田 宗孝

    日本呼吸器外科学会雑誌   29 ( 3 )   O41 - 2   2015.4

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  • Surgical Treatment for Synchronous Primary Lung Adenocarcinomas Reviewed

    Yoshihiro Ishikawa, Haruhiko Nakayama, Hiroyuki Ito, Tomoyuki Yokose, Masahiro Tsuboi, Teppei Nishii, Munetaka Masuda

    ANNALS OF THORACIC SURGERY   98 ( 6 )   1983 - 1988   2014.12

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    DOI： 10.1016/j.athoracsur.2014.07.006

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  • Oligo Metastasisを伴う肺癌に対する原発巣切除の意義

    安藤 耕平, 田尻 道彦, 大森 隆広, 稲福 賢司, 長澤 伸介, 福田 美緒, 菊池 章友, 足立 広幸, 永島 琢也, 西井 鉄平, 高橋 航, 山本 健嗣, 山仲 一輝, 渡部 克也, 熊切 寛, 益田 宗孝

    肺癌   54 ( 5 )   565 - 565   2014.10

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  • Clinicopathological features and EGFR gene mutation status in elderly patients with resected non-small-cell lung cancer Reviewed

    Teppei Nishii, Tomoyuki Yokose, Yohei Miyagi, Yataro Daigo, Hiroyuki Ito, Tetsuya Isaka, Kentaro Imai, Shuji Murakami, Tetsuro Kondo, Haruhiro Saito, Fumihiro Oshita, Kouzo Yamada, Shoichi Matsukuma, Masahiro Tsuboi, Haruhiko Nakayama, Munetaka Masuda

    BMC CANCER   14 ( 14 )   610   2014.8

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    DOI： 10.1186/1471-2407-14-610

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  • Comparison between CT tumor size and pathological tumor size in frozen section examinations of lung adenocarcinoma Reviewed

    Tetsuya Isaka, Tomoyuki Yokose, Hiroyuki Ito, Naoko Imamura, Masato Watanabe, Kentaro Imai, Teppei Nishii, Tetsukan Woo, Kouzo Yamada, Haruhiko Nakayama, Munetaka Masuda

    LUNG CANCER   85 ( 1 )   40 - 46   2014.7

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    DOI： 10.1016/j.lungcan.2014.03.023

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  • 非小細胞肺癌切除例における、スキップpN2転移症例の検討

    稲福 賢司, 山本 健嗣, 前原 孝光, 足立 広幸, 藤井 慶太, 安藤 耕平, 石川 善啓, 永島 琢也, 西井 鉄平, 禹 哲漢, 正津 晶子, 山仲 一輝, 渡部 克也, 熊切 寛, 坪井 正博, 益田 宗孝

    日本呼吸器外科学会雑誌   28 ( 3 )   O18 - 6   2014.4

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  • I期非小細胞肺癌に対する縮小手術の予後と初再発部位の検討

    渡部 克也, 五来 厚生, 足立 広幸, 安藤 耕平, 永島 琢也, 西井 鉄平, 高橋 航, 山本 健嗣, 山仲 一輝, 熊切 寛, 坪井 正博, 益田 宗孝

    日本呼吸器外科学会雑誌   28 ( 3 )   O1 - 4   2014.4

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  • 臨床病期I期肺癌(5cm以下)に対する肺葉切除症例におけるアプローチ別予後・再発形式の検討

    永島 琢也, 椎野 王久, 坪井 正博, 乾 健二, 安藤 耕平, 足立 広幸, 石川 善啓, 熊切 寛, 高橋 航, 西井 鉄平, 藤井 慶太, 山本 健嗣, 山仲 一輝, 渡部 克也, 禹 哲漢, 益田 宗孝

    日本呼吸器外科学会雑誌   28 ( 3 )   RS6 - 4   2014.4

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  • Clinicopathological features and EGFR gene Reviewed

    Teppei Nishii

    BMV Cancer   14   610   2014

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  • Case of solitary pulmonary capillary hemangioma: Pathological features based on frozen section analysis Reviewed

    Tetsuya Isaka, Tomoyuki Yokose, Hiroyuki Ito, Kota Washimi, Naoko Imamura, Masato Watanabe, Kentaro Imai, Teppei Nishii, Kouzo Yamada, Haruhiko Nakayama, Munetaka Masuda

    PATHOLOGY INTERNATIONAL   63 ( 12 )   615 - 618   2013.12

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    DOI： 10.1111/pin.12120

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  • I期肺癌に対する縮小手術の予後と再発部位の検討

    渡部 克也, 五来 厚生, 足立 広幸, 安藤 耕平, 永島 琢也, 西井 鉄平, 高橋 航, 山本 健嗣, 山仲 一輝, 熊切 寛, 坪井 正博, 益田 宗孝

    肺癌   53 ( 5 )   591 - 591   2013.10

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  • 多中心性発生と考えられた同時多発胸腺腫の一切除例

    西井 鉄平, 中山 治彦, 今村 奈緒子, 渡部 真人, 有賀 直広, 今井 健太郎, 禹 哲漢, 伊藤 宏之, 益田 宗孝

    日本胸部外科学会関東甲信越地方会要旨集   ( 162回 )   29 - 29   2013.6

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  • IA期肺癌に対する肺葉切除症例におけるアプローチ別予後解析

    永島 琢也, 小島 陽子, 石川 善啓, 大森 隆広, 田尻 道彦, 足立 広幸, 安藤 耕平, 西井 鉄平, 高橋 航, 山本 健嗣, 山仲 一輝, 渡部 克也, 熊切 寛, 坪井 正博, 益田 宗孝, 横浜市立大学外科治療学呼吸器外科グループ

    日本呼吸器外科学会雑誌   27 ( 3 )   P33 - 03   2013.4

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  • 非小細胞肺癌pN2術後早期の再発リスク因子の検討

    伊坂 哲哉, 高橋 航, 前原 孝光, 足立 広幸, 安藤 耕平, 永島 琢也, 西井 鉄平, 山本 健嗣, 山仲 一輝, 渡部 克也, 熊切 寛, 坪井 正博, 益田 宗孝, 横浜市立大学外科治療学呼吸器外科グループ

    日本呼吸器外科学会雑誌   27 ( 3 )   P08 - 01   2013.4

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  • 肺癌術後再発と臓側胸膜浸潤との関係 肺癌取扱い規約第7版を再考する

    足立 広幸, 諸星 隆夫, 野間 大督, 末松 秀明, 安藤 耕平, 永島 琢也, 西井 鉄平, 高橋 航, 山本 健嗣, 山仲 一輝, 渡部 克也, 熊切 寛, 坪井 正博, 益田 宗孝, 横浜市立大学外科治療学呼吸器外科グループ

    日本呼吸器外科学会雑誌   27 ( 3 )   P07 - 06   2013.4

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  • 80歳以上高齢者肺癌手術症例の検討

    鮫島 譲司, 渡部 克也, 足立 広幸, 安藤 耕平, 永島 琢也, 西井 鉄平, 高橋 航, 山本 健嗣, 山仲 一輝, 熊切 寛, 坪井 正博, 益田 宗孝, 横浜市立大学外科治療学呼吸器外科グループ

    日本呼吸器外科学会雑誌   27 ( 3 )   P17 - 06   2013.4

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  • p-N2非小細胞肺癌切除例に関する臨床的予後因子の検討

    高橋 航, 伊坂 哲哉, 前原 孝光, 足立 広幸, 安藤 耕平, 永島 琢也, 西井 鉄平, 山本 健嗣, 山仲 一輝, 渡部 克也, 熊切 寛, 坪井 正博, 益田 宗孝, 横浜市立大学外科治療学呼吸器外科グループ

    日本呼吸器外科学会雑誌   27 ( 3 )   P08 - 13   2013.4

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  • Oligometastatic肺癌に対する原発巣切除症例の検討

    安藤 耕平, 天野 新也, 坂本 和裕, 足立 広幸, 永島 琢也, 西井 鉄平, 高橋 航, 山本 健嗣, 山仲 一輝, 渡部 克也, 熊切 寛, 坪井 正博, 益田 宗孝, 横浜市立大学外科治療学呼吸器外科グループ

    日本呼吸器外科学会雑誌   27 ( 3 )   P22 - 04   2013.4

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  • 原発性肺癌切除例における重複癌の検討

    藤井 慶太, 山本 健嗣, 利野 靖, 足立 広幸, 安藤 耕平, 永島 琢也, 西井 鉄平, 高橋 航, 山仲 一輝, 渡部 克也, 熊切 寛, 坪井 正博, 益田 宗孝, 横浜市立大学外科治療学呼吸器外科グループ

    日本呼吸器外科学会雑誌   27 ( 3 )   P21 - 02   2013.4

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  • 女性肺癌切除例202例の臨床的検討

    齋藤 志子, 熊切 寛, 足立 広幸, 安藤 耕平, 永島 琢也, 西井 鉄平, 高橋 航, 山本 健嗣, 山仲 一輝, 渡部 克也, 坪井 正博, 益田 宗孝, 横浜市立大学外科治療学呼吸器外科グループ

    日本呼吸器外科学会雑誌   27 ( 3 )   P30 - 03   2013.4

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  • 原発性肺癌に対する縮小手術の予後と再発部位の検討

    渡部 克也, 鮫島 譲司, 足立 広幸, 安藤 耕平, 永島 琢也, 西井 鉄平, 高橋 航, 山本 健嗣, 山仲 一輝, 熊切 寛, 坪井 正博, 益田 宗孝, 横浜市立大学外科治療学呼吸器外科グループ

    日本呼吸器外科学会雑誌   27 ( 3 )   P34 - 04   2013.4

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  • Unique mutation, accelerated mTOR signaling and angiogenesis in the pulmonary cysts of Birt-Hogg-Dubé syndrome. Reviewed

    NISHII Teppei

    Pathol Int.   63 ( 1 )   45 - 55   2013.1

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    DOI： 10.1111/pin.12028

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  • Elevated microsatellite alterations at selected tetra-nucleotide (EMAST) in non-small cell lung cancers--a potential determinant of susceptibility to multiple malignancies. Reviewed

    Arai H, Okudela K, Oshiro H, Komitsu N, Mitsui H, Nishii T, Tsuboi M, Nozawa A, Noishiki Y, Ohashi K, Inui K, Masuda M

    International journal of clinical and experimental pathology   6 ( 3 )   395 - 410   2013

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  • A case of pleomorphic carcinoma of the lung suspected from infectious bulla Reviewed

    Teppei Nishii, Taketsugu Yamamoto, Hiromasa Arai, Kenji Inui, Munetaka Masuda

    Asian Cardiovascular and Thoracic Annals   20 ( 5 )   610   2012.10

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    DOI： 10.1177/0218492311435687

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  • A CASE OF MALIGNANT ECCRINE SPIRADENOMA WITH PULMONARY METASTASIS

    HASHIMOTO Kazuki, NISHII Teppei, ARAI Hiromasa, ITOH Ayako, INUI Kenji, MASUDA Munetaka

    The journal of the Japanese Practical Surgeon Society   73 ( 9 )   2231 - 2234   2012.9

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    A 75-year-old man developed a left middle finger tumor. The tumor was diagnosed as malignant eccrine spiradenoma, and he underwent amputation of the left middle finger ; a lymph node resection of the left axilla was also done. One year later, a chest CT scan revealed a small nodule in the apex of the left lung. To confirm the diagnosis, a partial resection of the left lung was performed during video-assisted thoracoscopic surgery. On histopathology, the pulmonary tumor was diagnosed as a metastasis of the malignant eccrine spiradenoma. Subsequently, 5 years after the left lung resection a partial resection of the right lung was required due to the presence of a metastasis. Currently, the patient is alive without evidence of recurrence. We report this rare case, together with a review of the relevant literature.

    DOI： 10.3919/jjsa.73.2231

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  • Lung adenocarcinoma with Lambert-Eaton myasthenic syndrome indicated by voltage-gated calcium channel: a case report. Reviewed International journal

    Arai H, Inui K, Hashimoto K, Kan-O K, Nishii T, Kishida H, Okudela K, Tsuboi M, Nozawa A, Kaneko T, Masuda M

    Journal of medical case reports   6   281 - 281   2012.9

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    INTRODUCTION: Lambert-Eaton myasthenic syndrome is a rare disorder and it is known as a paraneoplastic neurological syndrome. Small cell lung cancer often accompanies this syndrome. Lambert-Eaton myasthenic syndrome associated with lung adenocarcinoma is extremely rare; there are only a few reported cases worldwide. CASE PRESENTATION: A 75-year-old Japanese man with a past history of chronic rheumatoid arthritis and Sjögren syndrome was diagnosed with Lambert-Eaton myasthenic syndrome by electromyography and serum anti-P/Q-type voltage-gated calcium channel antibody level preceding the diagnosis of lung cancer. A chest computed tomography to screen for malignant lesions revealed an abnormal shadow in the lung. Although a histopathological examination by bronchoscopic study could not reveal the malignancy, lung cancer was mostly suspected after the results of a chest computed tomography and [18F]-fluorodeoxyglucose positron emission tomography. An intraoperative diagnosis based on the frozen section obtained by tumor biopsy was adenocarcinoma so the patient underwent a lobectomy of the right lower lobe and lymph node dissection with video-assisted thoracoscopic surgery. The permanent pathological examination was the same as the frozen diagnosis (pT2aN1M0: Stage IIa: TNM staging 7th edition). Immunohistochemistry revealed that most of the cancer cells were positive for P/Q-type voltage-gated calcium channel. CONCLUSIONS: Our case is a rare combination of Lambert-Eaton myasthenic syndrome associated with lung adenocarcinoma, rheumatoid arthritis and Sjögren syndrome, and to the best of our knowledge it is the first report that indicates the presence of voltage-gated calcium channel in lung adenocarcinoma by immunostaining.

    DOI： 10.1186/1752-1947-6-281

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  • Right upper lobectomy in patients with anomaly of the right main bronchus

    Kenji Inafuku, Teppei Nishii, Hiromasa Arai, Kenji Inui

    European Journal of Cardio-thoracic Surgery   42 ( 1 )   189   2012.7

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    DOI： 10.1093/ejcts/ezr323

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  • Lung cancer associated with an azygos lobe successfully treated with video-assisted thoracoscopic surgery. Reviewed

    Arai H, Inui K, Kano K, Nishii T, Kaneko T, Mano H, Sasaki T, Masuda M

    Asian journal of endoscopic surgery   5 ( 2 )   96 - 99   2012.5

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  • THE OPERATION FOR THYMOMAS : THYMO-PARTIAL THYMECTOMY BY ANTEROLATERAL INCISION WITH VIDEO-ASSISTED THORACOSCOPIC SURGERY

    ARAI Hiromasa, INUI Kenji, NISHII Teppei, YUKAWA Norio, RINO Yasushi, MASUDA Munetaka

    The journal of the Japanese Practical Surgeon Society   73 ( 2 )   293 - 298   2012.2

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    We report a total of ten cases of thymoma (in Stage I/II according to the Masaoka's classification) performed thymo-partial thymectomy by anterolateral incision with video-assisted thoracoscopic surgery. The subjects were three men and seven women, with an average age of 58±11.0 years old. Of the ten patients, three underwent associated resection of other organs, another three had postoperative complications, one had phrenic nerve paralysis associated with combined resection, and one had been suffering from atrial fibrillation before the operation. In accordance with the WHO classification, the most common histopathological diagnosis was Type AB in five cases (50%), and six (60%) was noted in StageI according to the Masaoka's classification after the operation. An average operating time was 92.3±39.2 minutes. An average operative blood loss was 20.5±34.1 ml. An average time of a chest tube drainage was 1.50±0.85 days, and an average hospital stay was 7.4±4.62 days. There have been no signs of recurrent disease in all the patients.<BR>Thoracoscopy-assisted thymo-partial thymectomy by anterolateral incision is considered to be a minimally invasive and safe operative procedure for selected thymoma patients.

    DOI： 10.3919/jjsa.73.293

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  • Intrapleural analgesia using ropivacaine for postoperative pain relief after minimally invasive thoracoscopic surgery. Reviewed

    Ishikawa Y, Maehara T, Nishii T, Yamanaka K, Adachi H, Saito S, Masuda M

    Annals of thoracic and cardiovascular surgery : official journal of the Association of Thoracic and Cardiovascular Surgeons of Asia   18 ( 5 )   429 - 433   2012

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    Purpose: to evaluate the efficacy and safety of intrapleural analgesia (IPA) using ropivacaine after thoracoscopic surgery, compared with thoracic epidural analgesia (TEA) using ropivacaine.<br>Methods: forty patients undergoing thoracoscopic bullectomy for spontaneous pneumothorax were randomly assigned to one of two groups. IPA group (n = 20) received intermittent bolus injection of 0.375% ropivacaine into intrapleural space two times; at the end of operation and one more time as the pain increased. TEA group (n = 20) received continuous epidural analgesia with 0.375% ropivacaine. Transrectal diclofenac was administered as an additional analgesic. Pain was assessed on the basis of additional analgesics requirements and by using a visual analog scale (VAS).<br>Results: the time courses of VAS scores along the postoperative time course were not significantly different (p = 0.175). Consumption of transrectal diclofenac was significantly smaller in IPA group (p = 0.025). No major complications appeared in both groups, and incidence of adverse symptoms was not different.<br>Conclusions: in IPA group, pain was managed with less consumption of additional analgesics. IPA could be one of the good choices after thoracoscopic surgery for its efficacy, safety, and benefit of easy placement of the catheter.

    DOI： 10.5761/atcs.oa.11.01854

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  • 統合失調症合併患者に対する肺癌手術の検討

    西井 鉄平, 山本 健嗣, 神尾 一樹, 森山 雄介, 渡邉 恵介, 足立 広幸, 山口 展弘, 吉川 純子, 後藤 秀人, 新海 正晴, 荒井 宏雅, 金子 猛, 乾 健二, 利野 靖, 益田 宗孝

    肺癌   51 ( 5 )   550 - 550   2011.10

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  • 胸壁合併切除を施行した非小細胞肺癌の検討

    山本 健嗣, 足立 広幸, 西井 鉄平, 荒井 宏雅, 乾 健二, 金子 猛, 利野 靖, 益田 宗孝

    肺癌   51 ( 5 )   501 - 501   2011.10

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  • 非小細胞肺癌におけるタイト結合蛋白claudin-7の発現の臨床的意義

    山本 健嗣, 大島 貴, 西井 鉄平, 荒井 宏雅, 乾 健二, 足立 広幸, 湯川 寛夫, 和田 修幸, 利野 靖, 益田 宗孝, 今田 敏夫

    日本外科学会雑誌   112 ( 臨増1-2 )   583 - 583   2011.5

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  • A Case of Primary Lung Cancer with Malignant Pleural Effusion but Without Visceral Pleural Invasion or Dissemination

    Arai Hiromasa, Inui Kenji, Nishii Teppei, Chiba Sawako, Oshiro Hisashi, Masuda Munetaka

    JJLC   51 ( 7 )   793 - 797   2011

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    <i><b>Background</b></i>. In primary lung cancer cases without visceral pleura invasion or dissemination, cancer cells are rarely confirmed in the pleural effusion intraoperatively. The clinicopathologic findings are thus important for TNM staging by providing the natural history of the disease progression, although the precise mechanisms remain unclear. <i><b>Case</b></i>. A 68-year-old man with bloody sputum was given a diagnosis of lung adenocarcinoma arising from the left upper lobe. The clinical TNM stage was IA (cT1bN0M0). He underwent left upper lobe lobectomy and lymph node dissection (ND2a) with video-assisted thoracoscopic surgery. The intraoperative findings revealed minor serous pleural effusion, but there was no pleural invasion or pleural dissemination. His surgical diagnosis was sT1bN0M0D0E1 (+) serousPL0PM0: stage IA, and the histopathologic diagnosis was mixed adenocarcinoma with hilar lymph node metastasis (N1). No extra-nodal invasion was observed. Microscopic examination did not show any invasion of the visceral pleura (PL0), but cancer cells were noted in the pleural effusion on cytological examination. The final histopathologic TNM stage was determined as pT1bN1 (#11) M1a (E+), stage IV. <i><b>Conclusion</b></i>. We report a rare case of primary lung cancer with malignant pleural effusion but without visceral pleural invasion. Malignant pleural effusion is an important factor for TNM staging and for determining the treatment strategies for lung cancer. During surgery, even if no visceral pleura invasion is noted, intraoperative lavage or pleural effusion cytology should be routinely performed.<br>

    DOI： 10.2482/haigan.51.793

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    Other Link： http://search.jamas.or.jp/link/ui/2012173863

  • P6-6 気管支分岐異常を伴った原発性肺癌の一切除例(肺癌,ポスター6,第34回日本呼吸器内視鏡学会学術集会)

    稲福 賢司, 西井 鉄平, 荒井 宏雅, 乾 健二, 渡邉 恵介, 星野 昌子, 山口 展弘, 後藤 秀人, 新海 正晴, 伊藤 優, 金子 猛, 益田 宗孝

    気管支学   33   S238   2011

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    Language：Japanese   Publisher：特定非営利活動法人 日本呼吸器内視鏡学会  

    DOI： 10.18907/jjsre.33.Special_S238_3

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  • Reduced expression of claudin-7 is associated with poor outcome in non-small cell lung cancer Reviewed International journal

    Yamamoto T, Oshima T, Yoshihara K, Yamanaka S, Nishii T, Arai H, Inui K, Kaneko T, Nozawa A, Woo T, Rino Y, Masuda M, Imada T

    Oncol Lett   1 ( 3 )   501 - 505   2010.5

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    Claudin-7 is a tight junction protein that plays an important role in tumorigenesis, tumor invasion and metastasis. We examined the clinical significance of claudin-7 expression in 75 postsurgical non-small cell lung cancer (NSCLC) patients. Claudin-7 expression was measured immunohistochemically and was found to be high in 25 patients (33.3%) and low in 50 (66.7%). Survival was significantly poorer in patients with claudin-7-low than in those with claudin-7-high NSCLCs (P=0.024). In particular, survival was significantly poorer in patients with claudin-7-low than in those with claudin-7-high squamous cell carcinomas (P=0.011). A reduced expression of claudin-7 was associated with poor outcome in NSCLCs. Claudin-7 may thus be a useful biomarker and a potential therapeutic target in patients with NSCLC.

    DOI： 10.3892/ol_00000088

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  • Clinical report about three advanced gastroenterological cancer cases which palliative ileostomy were performed

    Masakatsu Numata, Hiroyasu Tanabe, Kouji Numata, Teppei Nishii, Yoshihiro Suzuki, Hiroyuki Oosawa, Kazuyuki Tani, Ryuji Shiraishi, Yasushi Rino, Munetaka Masuda

    Yokohama Medical Journal   61 ( 1 )   37 - 41   2010

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  • Well-differentiated extraskeletal osteosarcoma arising from the retroperitoneum that recurred as anaplastic spindle cell sarcoma. Reviewed

    Arai H, Rino Y, Nishii T, Yukawa N, Wada N, Oshiro H, Ishida T, Nakaigawa N, Masuda M

    Case reports in medicine   2010   327591   2010

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  • Video-assisted thoracoscopic surgery for pulmonary arteriovenous malformations: Report of five cases Reviewed

    Yoshihiro Ishikawa, Kazuki Yamanaka, Teppei Nishii, Keita Fujii, Yasushi Rino, Takamitsu Maehara

    General Thoracic and Cardiovascular Surgery   56 ( 4 )   187 - 190   2008.4

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    DOI： 10.1007/s11748-007-0215-6

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  • A case of primary clear cell adenocarcinoma of the lung

    NISHII Teppei, RINO Yasushi, ARAI Hiromasa, CHIBA Akihiko, OSHIRO Hisashi, TAKANASHI Yoshinori

    The Journal of the Japanese Association for Chest Surgery   21 ( 2 )   165 - 169   2007.3

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    Language：Japanese   Publisher：The Japanese Association for Chest Surgery  

    We report a 76-year-old man who underwent surgery for a clear cell adenocarcinoma detected on a health checkup. Chest computed tomography (CT) revealed a tumor at the S<SUP>3</SUP> of the left lung. Transbronchial lung biopsy did not lead to a definitive diagnosis, and partial resection of the left lung was performed. Because rapid pathological diagnosis using a frozen specimen suggested adenocarcinoma, superior lobectomy of the left lung and mediastinal lymph node dissection were performed. Systemic diagnostic imaging before and after surgery did not reveal any tumorous lesion in other organs, and the clinical findings suggested a primary tumor of the lung. Postoperative pathological investigation showed that clear cells comprised 90% or more of the lesion, with small foci of papillary structure. Immunohistochemically, the tumor was positive for keratin, EMA, thyroid transcription factor-1, and surfactant apoprotein A, and negative for HMB45, suggesting a primary clear cell adenocarcinoma of the lung. There has been no recurrence during the 22 months of postoperative follow-up.

    DOI： 10.2995/jacsurg.21.165

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  • Successful treatment of multiple small-bowel perforations caused by cytomegalovirus in a patient with malignant lymphoma: Report of a case Reviewed

    Teppei Nishii, Yasushi Rino, Kohei Ando, Kenichi Matsuzu, Hiroo Wada, Akihiko Chiba, Hiromasa Arai, Akio Ashida, Kimiatsu Hasuo, Yoshiaki Inayama, Yoshinori Takanashi

    SURGERY TODAY   36 ( 10 )   930 - 933   2006.10

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    DOI： 10.1007/s00595-006-3274-x

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  • A CASE PRESENTED INTESTINAL OBSTRUCTION DURING CHEMOTHERAPY FOR MALIGNANT LYMPHOMA OF THE ILEOCECUM

    NISHII Teppei, RINO Yasushi, HASUO Kimiatsu, INAYAMA Yoshiaki, TAKANASHI Yoshinori

    The journal of the Japanese Practical Surgeon Society   67 ( 3 )   645 - 648   2006

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    Language：Japanese   Publisher：Japan Surgical Association  

    The patient was a 59-year-old male with malignant lymphoma (non-Hodgkin's lymphoma) mainly located in the ileocecum. After 2 courses of chemotherapy with CHOP for the malignant lymphoma, the patient developed intestinal obstruction on June 22, 2004. Although surgical treatment was indicated, he presented myelosuppression (WBC count=1, 800/μl) at the onset of ileus. Therefore, myelosuppression was treated by G-CSF, and when the WBC count became to above 3, 000/μl, he underwent ileocecal resection on August 26, 2004. Pathohistological findings included severe fibrosis and inflammatory cells infiltrating in the stenotic region, as well as some concentration of large atypical lymphocytes, resulting in the diagnosis of diffuse large B-cell lymphoma. The postoperative course was favorable, and oral food ingestion and medical treatment for the lymphoma were resumed. Along with recent advances in chemotherapy, we are demanded to establish careful therapeutic strategy for condidates of operation for malignant lymphoma with myelosuppression, after considering whether elective surgery can be selected or not.

    DOI： 10.3919/jjsa.67.645

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  • A Case of Spindle Cell Carcinoid Tumor of the Thymus Associated With Cushing's Syndrome

    Takei Hidefumi, Nishii Teppei, Maehara Takamitsu, Kakuta Yukio

    JJLC   44 ( 3 )   183 - 187   2004

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    Language：Japanese   Publisher：The Japan Lung Cancer Society  

    <I><B>Background.</B></I> Ectopic production of adrenocorticotropic hormone (ACTH) associated with Cushing's syndrome has been identified with a variety of malignant tumors, including small cell lung cancer and bronchial carcinoid. However, carcinoid tumors of the thymus associated with Cushing's syndrome are extremely rare. <I><B>Case.</B></I> A 58-year-old woman was admitted to our hospital with moon face, worsening edema of legs, and hypokalemia. Laboratory values disclosed a high serum ACTH level and a high level of serum cortisol. A chest CT scan revealed a 2-cm anterior mediastinal tumor. Thoracoscopic tumor resection was performed under the diagnosis of an ectopic ACTH secreting thymic tumor. Histologic examination revealed a spindle cell carcinoid of the thymus with immunoreactivity for ACTH. The serum ACTH level decreased and her clinical symptoms resolved after tumor resection. <I><B>Conclusion.</B></I> We described a rare case of spindle cell carcinoid of the thymus associated with Cushing's syndrome.

    DOI： 10.2482/haigan.44.183

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MISC

  • 極めて稀な縦隔型A7a+8bを有した右下葉肺癌の1切除例

    鮫島 譲司, 伊藤 宏之, 中山 治彦, 西井 鉄平, 永島 琢也, 益田 宗孝

    日本呼吸器外科学会雑誌   31 ( 5 )   684 - 688   2017.7

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    Language：Japanese   Publisher：(NPO)日本呼吸器外科学会  

    DOI： 10.2995/jacsurg.31.684

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  • Alternative Follow-Up Methods Based on Recurrence Patterns after Surgery for Non-Small Cell Lung Cancer

    Katsuya Watanabe, Kentaro Sakamaki, Teppei Nishii, Atsuo Gorai, Taketsugu Yamamoto, Takuya Nagashima, Kohei Ando, Yoshihiro Ishikawa, Tetsukan Woo, Hiroyuki Adachi, Yutaka Kumakiri, Takamitsu Maehara, Haruhiko Nakayama, Munetaka Masuda

    JOURNAL OF THORACIC ONCOLOGY   12 ( 1 )   S245 - S246   2017.1

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    Language：English   Publishing type：Research paper, summary (international conference)  

    DOI： 10.1016/j.jtho.2016.11.231

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  • Suspected Aerogenous Lung Metastases From Nasopharyngeal Cancer

    Masashi Nagata, Haruhiko Nakayama, Tomohiko Matsuzaki, Hideyuki Furumoto, Tetsuya Isaka, Teppei Nishii, Madoka Furukawa, Akira Kubota, Hiroyuki Ito, Tomoyuki Yokose

    ANNALS OF THORACIC SURGERY   101 ( 5 )   E157 - E159   2016.5

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  • Comparison of thin-section computed tomographic images, pathological findings, and clinical features of resected small lung adenocarcinomas 20 cm or less in diameter containing micropapillary elements

    23 ( 3 )   180 - 186   2016.5

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  • 完全切除された非小細胞肺癌における希少遺伝子変異の検討

    西井鉄平, 横瀬智之, 宮城洋平, 醍醐弥太郎, 伊藤宏之, 山田耕三, 中山治彦

    日本肺癌学会総会号   56th ( 5 )   469 - 469   2015.10

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    Language：Japanese   Publisher：(NPO)日本肺癌学会  

    J-GLOBAL

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  • Next-Generation Sequencing Analysis of Driver Gene Mutations in Pleomorphic Carcinoma of the Lung

    Saki Manabe, Rika Kasajima, Yohei Miyagi, Teppei Nishii, Tomoyuki Yokose, Shuji Murakami, Tetsuro Kondo, Haruhiro Saito, Masanori Hashimoto, Hideyuki Furumoto, Tetsuya Isaka, Hiroyuki Ito, Haruhiko Nakayama, Takeshi Kaneko, Kouzo Yamada

    JOURNAL OF THORACIC ONCOLOGY   10 ( 9 )   S310 - S310   2015.9

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  • Rare Gene Mutations in Japanese Surgically Resected Non-Small-Cell Lung Cancer Patients

    Nishii Teppei, Yokose Tomoyuki, Miyagi Yohei, Daigo Yataro, Matsuzaki Tomohiko, Nagata Masashi, Isaka Tetsuya, Furumoto Hideyuki, Ito Hiroyuki, Manabe Saki, Murakami Shuji, Kondo Tetsuro, Saito Haruhiro, Yamada Kouzo, Masuda Munetaka, Nakayama Haruhiko

    JOURNAL OF THORACIC ONCOLOGY   2015.9

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  • PS-032-1 高齢者肺癌の長期治療成績 : 葉切に対する術前評価と認知機能に関しての検討(PS-032 肺 高齢者-2・その他,ポスターセッション,第114回日本外科学会定期学術集会)

    伊藤 宏之, 中山 治彦, 西井 鉄平, 今井 健太郎, 今村 奈緒子, 渡部 真人, 益田 宗孝

    日本外科学会雑誌   115 ( 2 )   638 - 638   2014.3

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    Language：Japanese   Publisher：一般社団法人日本外科学会  

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  • OP-067-5 摘出肺検体の喀痰細胞診と肺癌組織型との関連性の検討(OP-067 肺 診断,一般演題,第114回日本外科学会定期学術集会)

    伊坂 哲哉, 横瀬 智之, 鷲見 公太, 今村 奈緒子, 渡部 真人, 今井 健太郎, 西井 鉄平, 伊藤 宏之, 山田 耕三, 中山 治彦, 坪井 正博, 益田 宗孝

    日本外科学会雑誌   115 ( 2 )   434 - 434   2014.3

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    Language：Japanese   Publisher：一般社団法人日本外科学会  

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  • 摘出肺検体の喀痰細胞診と肺癌組織型との関連性の検討

    伊坂 哲哉, 横瀬 智之, 鷲見 公太, 今村 奈緒子, 渡部 真人, 今井 健太郎, 西井 鉄平, 伊藤 宏之, 山田 耕三, 中山 治彦, 坪井 正博, 益田 宗孝

    日本外科学会雑誌   115 ( 臨増2 )   434 - 434   2014.3

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  • UNCERTAIN RESECTION DUE TO INCOMPLETE INTRAOPERATIVE NODAL ASSESSMENT

    Taketsugu Yamamoto, Takamitsu Maehara, Kenji Inafuku, Ko Takahashi, Hiroyuki Adachi, Kohei Ando, Yoshihiro Ishikawa, Teppei Nishii, Kazuki Yamanaka, Katsuya Watanabe, Yutaka Kumakiri, Takuya Nagashima, Masahiro Tsuboi, Keita Fujii, Munetaka Masuda

    JOURNAL OF THORACIC ONCOLOGY   8   S523 - S523   2013.11

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  • CLINICOPATHOLOGICAL FEATURES IN NON-SMALL CELL LUNG CANCER PATIENTS WITH EGFR AND KRAS MUTATIONS

    Teppei Nishii, Tomoyuki Yokose, Yohei Miyagi, Hiroyuki Ito, Masato Watanabe, Naoko Imamura, Tetsuya Isaka, Kentaro Imai, Fumi Karino, Shuji Murakami, Tetsuro Kondo, Haruhiro Saito, Fumihiro Oshita, Kouzo Yamada, Haruhiko Nakayama, Munetaka Masuda

    JOURNAL OF THORACIC ONCOLOGY   8   S965 - S965   2013.11

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  • THE CORRELATION BETWEEN COMPUTED TOMOGRAPHY FINDINGS AND THE CLINICOPATHOLOGICAL FACTORS IN SMALL-SIZED ADENOCARCINOMAS OF THE LUNG (10 MM OR LESS IN DIAMETER)

    Fumi Karino, Shuji Murakami, Tetsuro Kondo, Haruhiro Saito, Fumihiro Oshita, Kentaro Imai, Teppei Nishii, Hiroyuki Ito, Haruhiko Nakayama, Tetsuya Isaka, Tomoyuki Yokose, Kouzo Yamada

    JOURNAL OF THORACIC ONCOLOGY   8   S1264 - S1264   2013.11

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  • A CASE OF MESENTERIAL TUMOR WHICH METASTASIZED TO LUNG 16 YEARS AFTER RESECTION

    KANO Kazuki, NISHII Teppei, ARAI Hiromasa, KAWACHI Kae, INUI Kenji, MASUDA Munetaka

    73 ( 4 )   1013 - 1016   2012.4

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  • 新規遺伝子変異を示したBirt-Hogg-Dube症候群の1例 反復性気胸を伴う多発性肺嚢胞の分子病理学的検討

    西井 鉄平, 田辺 美樹子, 奥寺 康司, 田中 玲子, 松澤 哲宏, 野澤 昭典, 中谷 行雄, 古屋 充子

    日本病理学会会誌   101 ( 1 )   394 - 394   2012.3

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  • A CASE OF GIANT MEDIASTINAL CYST RESECTED DURING VIDEO-ASSISTED THORACIC SURGERY

    NISHII Teppei, OSAWA Hiroyuki, SHIRAISHI Ryuji, TAKAHASHI Masao, INUI Kenji, MASUDA Munetaka

    72 ( 8 )   1964 - 1968   2011.8

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  • CLINICOPATHOLOGICAL SIGNIFICANCE OF THE CIRCADIAN PROTEINS EXPRESSION IN PATIENTS WITH NON-SMALL CELL LUNG CANCER

    Teppei Nishii, Takashi Oshima, Taketsugu Yamamoto, Kazue Yoshihara, Hiromasa Arai, Kenji Inui, Takeshi Kaneko, Akinori Nozawa, Munetaka Masuda, Toshio Imada

    JOURNAL OF THORACIC ONCOLOGY   6 ( 6 )   S1507 - S1507   2011.6

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  • CLINICAL SIGNIFICANCE OF IGF-1R AND MMP-7 EXPRESSION IN PATIENTS WITH NON-SMALL CELL LUNG CANCER

    Taketsugu Yamamoto, Takashi Oshima, Kazue Yoshihara, Teppei Nishii, Hiromasa Arai, Kenji Inui, Hiroyuki Adachi, Yasushi Rino, Munetaka Masuda, Toshio Imada

    JOURNAL OF THORACIC ONCOLOGY   6 ( 6 )   S968 - S969   2011.6

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  • P-298 右中下葉無気肺を合併した肺原発悪性繊維性組織球症の1例(一般演題(ポスター)31 症例07,第48回日本肺癌学会総会号)

    正津 晶子, 前原 孝光, 西井 鉄平, 足立 広幸, 森川 哲行, 打越 暁, 菊岡 健太郎, 石田 安代, 赤川 玄樹, 日比 慎一郎, 宮崎 健二, 長谷川 直樹, 角田 幸雄

    肺癌   47 ( 5 )   599 - 599   2007.10

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Research Projects

  • 適応的に機能する急変対応システムの有用性と実装にむけた研究

    Grant number：21K10301  2021.4 - 2024.3

    日本学術振興会  科学研究費助成事業  基盤研究(C)

    中村 京太, 中島 和江, 佐藤 仁, 安部 猛, 土屋 慶子, 岡田 浩, 鈴木 渉太, 西井 鉄平

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    Grant amount：\3510000 （ Direct Cost: \2700000 、 Indirect Cost：\810000 ）

    令和3年度は、研究フィールドとなる横浜市立大学附属市民総合医療センターのRapid Response Team（以下、RRT）メンバーに研究概要を説明のうえ、研究倫理委員会に研究計画書を提出し審査を依頼した。しかし横浜市立大学の研究倫理審査に時間を要し、かつ修正を依頼されたため、現在再提出のうえ審査結果を待っている状況にある。
    横浜市立大学附属市民総合医療センターのRRTは、すでに稼働している医療安全上のシステムであるため、研究倫理審査が認められるまでの間も、RRT活動記録やコードブルー症例の記録、ならびにRRSの症例検討記録など、基礎データとなる症例実績は収集を継続している。
    研究施設外での情報収集活動としては、11月の救急医学会学術集会ならびに3月の集中治療医学会学術集会に参加し、RRSのセッションに参加し、情報収集とupdateを行った。
    また、2月には医療の質・安全学会主催のRRS研修会で講演した。参加者とのグループワークでは、RRSが”どのように”うまくいっているか？という本研究の鍵となるレジリエンス・エンジニアリング（Safety-II）のアプローチで考察することにより、各施設のRRSの役割と実績、可能性について議論を行った。
    なお、研究代表者の主たる勤務先が令和4年4月1日から横浜市立大学附属市民総合医療センターへ異動することを踏まえ、臨床倫理審査部門と相談のうえ、横浜市立大学のみでの研究倫理審査で進めるように予定を変更することで調整している。

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