Researcher Profile - Noriaki Iwahashi

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写真a

Noriaki Iwahashi

Organization

YCU Medical Center Associate Professor

Homepage

https://yokohama-circ.jp/about/staff.php

Profile

<学歴/職歴>

1997年横浜市立大学付属病院　臨床研修医

1999年横浜市立大学第二内科

1999年焼津市立病院　循環器科

2002年国立循環器病センター　心臓内科

2005年横浜市立大学附属市民総合医療センター

2007年横浜市立大学附属市民総合医療センター　助教

2015年横浜市立大学附属市民総合医療センター　講師

2023年横浜市立大学　医学部　循環器内科　准教授

2025年横浜市立大学附属市民総合医療センター　心臓血管センター　担当部長

<医師主導治験実施担当・責任医師>

＃心臓カテーテル検査・治療中に生じる難治性冠攣縮に対するファスジルの有効性及び安全性に関する無作為化、プラセボ対照二重盲検比較試験（医師主導治験）：論文化

2018/8/1-2020/8/20

多施設共同プラセボ対照無作為化二重盲検比較試験(第３相試験)

公益社団法人日本医師会

＃心筋保護を考慮した新しい急性心不全治療薬としてのエプレレノンの有効性を検討する臨床試験（無作為化プラセボ対照二重盲検比較試験）

2013/6/18-2018/12/28

多施設共同プラセボ対照無作為化二重盲検比較試験(第３相試験)

公益社団法人日本医師会

<所属学会　資格>

・医学博士 2007年横浜市立大学

・日本内科学会日本内科学会認定総合内科専門医指導医

・日本循環器学会　循環器専門医　代議員

・日本心臓病学会　FJCC　代議員

・日本心エコー図学会　SHD専門医　心エコー図専門医　認定専門技師試験審査員　認定専門医試験審査員

・日本超音波医学会　超音波専門医　超音波指導医　代議員

・日本心不全学会/日本不整脈心電学会　ICD/CRT合同研修セミナー修了　WCD処方医

・日本心血管インターベンション学会　インターベンション認定医

・日本心不全学会

・日本冠疾患学会

・日本肺高血圧・肺循環学会

・日本ポイントオブケア超音波学会

・日本心臓リハビリテーション学会

・アメリカ心臓病協会 AHA

・アメリカ心臓病学会 ACC

・欧州心臓病協会 ESC

・神奈川SHD研究会　理事

External link

Degree

医学博士 ( 2007 )

Research Interests

急性大動脈症候群
Acute coronary syndrome
心臓弁膜症
循環器救急
Cardiac rehabilitation
睡眠障害、PSGを用いた詳細な検討
糖代謝異常と循環器疾患の関連
COPD、肺気腫
運動負荷検査、運動負荷心臓超音波
肺高血圧
補助循環装置
心不全
心臓超音波検査

Research Areas

Life Science / Cardiology

Education

1997年福井医科大学（現.福井大学医学部) 医学部医学科

1991.4 - 1997.3

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Research History

Yokohama City University Associate professor Department of Cardiology, Yokohama City University School of Medicine

2023.4

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横浜市立大学付属市民総合医療センター心臓血管センター講師

2005.5 - 2023.3

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National Cerebral and Cardiovascular Center, Rese

2002.5 - 2005.4

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横浜市立大学第二内科関連病院循環器内科

1999.4 - 2002.4

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横浜市立大学付属病院臨床研修医

1997.4 - 1999.3

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Professional Memberships

日本肺高血圧・肺循環学会

2023.4

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日本核医学会

2016

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日本心不全学会

2010

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THE JAPAN SOCIETY OF ULTRASONICS IN MEDICINE

2003

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JAPANESE SOCIETY OF ECHOCARDIOGRAPHY

2001

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日本内科学会

1999

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THE JAPANESE CIRCULATION SOCIETY

1999

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JAPANESE COLLEGE OF CARDIOLOGY

1999

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JAPANESE ASSOCIATION OF CARDIOVASCULAR INTERVENTION AND THERAPEUTICS

1999

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Committee Memberships

横浜市立大学集中ケアユニット運営委員会

2023.4

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横浜市立大学救急委員会

2023.4

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横浜市立大学心肺蘇生・RRS運営チームワーキング

2023.4

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横浜市立大学働き方改革委員

2020

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(学会認定資格委員) 日本心エコー図学会認定専門技師、試験作成日本心エコー図学会認定専門医師、試験作成

2019

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横浜市立大学総合内科専攻医プログラム指導医

2018.4

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横浜市立大学臨床研究モニタ委員

2017

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Papers

Prognostic importance of glycemic variability on left ventricular reverse remodeling after the first episode of ST-segment elevation myocardial infarction. International journal

Yohei Hanajima, Noriaki Iwahashi, Jin Kirigaya, Mutsuo Horii, Yugo Minamimoto, Masaomi Gohbara, Takeru Abe, Kozo Okada, Yasushi Matsuzawa, Masami Kosuge, Toshiaki Ebina, Kiyoshi Hibi

Cardiovascular diabetology 22 ( 1 ) 202 - 202 2023.8

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BACKGROUND: This study aimed to investigate the effect of glycemic variability (GV), determined using a continuous glucose monitoring system (CGMS), on left ventricular reverse remodeling (LVRR) after ST-segment elevation myocardial infarction (STEMI). METHODS: A total of 201 consecutive patients with STEMI who underwent reperfusion therapy within 12 h of onset were enrolled. GV was measured using a CGMS and determined as the mean amplitude of glycemic excursion (MAGE). Left ventricular volumetric parameters were measured using cardiac magnetic resonance imaging (CMRI). LVRR was defined as an absolute decrease in the LV end-systolic volume index of > 10% from 1 week to 7 months after admission. Associations were also examined between GV and LVRR and between LVRR and the incidence of major adverse cardiovascular events (MACE; cardiovascular death, acute coronary syndrome recurrence, non-fatal stroke, and heart failure hospitalization). RESULTS: The prevalence of LVRR was 28% (n = 57). The MAGE was independent predictor of LVRR (odds ratio [OR] 0.98, p = 0.002). Twenty patients experienced MACE during the follow-up period (median, 65 months). The incidence of MACE was lower in patients with LVRR than in those without (2% vs. 13%, p = 0.016). CONCLUSION: Low GV, determined using a CGMS, was significantly associated with LVRR, which might lead to a good prognosis. Further studies are needed to validate the importance of GV in LVRR in patients with STEMI.

DOI： 10.1186/s12933-023-01931-3

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Prevention and management of critical care complications in cardiogenic shock: a narrative review. International journal

Jin Kirigaya, Noriaki Iwahashi, Kengo Terasaka, Ichiro Takeuchi

Journal of intensive care 11 ( 1 ) 31 - 31 2023.7

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BACKGROUND: Cardiogenic shock (CS) is a common cause of morbidity and mortality in cardiac intensive care units (CICUs), even in the contemporary era. MAIN TEXT: Although mechanical circulatory supports have recently become widely available and used in transforming the management of CS, their routine use to improve outcomes has not been established. Transportation to a high-volume center, early reperfusion, tailored mechanical circulatory supports, regionalized systems of care with multidisciplinary CS teams, a dedicated CICU, and a systemic approach, including preventing noncardiogenic complications, are the key components of CS treatment strategies. CONCLUSIONS: This narrative review aimed to discuss the challenges of preventing patients from developing CS-related complications and provide a comprehensive practical approach for its management.

DOI： 10.1186/s40560-023-00675-2

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Right ventricular strain and mechanical dispersion for heart failure with preserved ejection fraction. International journal

Noriaki Iwahashi

International journal of cardiology 374 83 - 84 2023.1

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DOI： 10.1016/j.ijcard.2022.12.052

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Unfavourable outcomes in patients with heart failure with higher preserved left ventricular ejection fraction. International journal

Nobuyuki Ohte, Shohei Kikuchi, Noriaki Iwahashi, Yoshiharu Kinugasa, Kaoru Dohi, Hiroyuki Takase, Kumiko Masai, Katsuji Inoue, Takahiro Okumura, Kenta Hachiya, Shuichi Kitada, Yoshihiro Seo

European heart journal. Cardiovascular Imaging 24 ( 3 ) 293 - 300 2022.12

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AIMS: Newly introduced drugs for heart failure (HF) have been reported to improve the prognosis of HF with preserved ejection fraction (HFpEF) in the lower range of left ventricular ejection fraction (LVEF). We hypothesized that a higher LVEF is related to an unfavourable prognosis in patients with HFpEF. METHODS AND RESULTS: We tested this hypothesis by analysing the data from a prospective multicentre cohort study in 255 patients admitted to the hospital due to decompensated HF (LVEF > 40% at discharge). The primary endpoint of this study was a composite outcome of all-cause death and readmission due to HF, and the secondary endpoint was readmission due to HF. LVEF and the mitral E/e' ratio were measured using echocardiography. In multicovariate parametric survival time analysis, LVEF [hazard ratio (HR) = 1.046 per 1% increase, P = 0.001], concurrent atrial fibrillation (AF) (HR = 3.203, P < 0.001), and E/e' (HR = 1.083 per 1.0 increase, P < 0.001) were significantly correlated with the primary endpoint. In addition to these covariates, angiotensin-converting enzyme inhibitor (ACEI)/angiotensin receptor blocker (ARB) use was significantly correlated with the secondary endpoint (HR = 0.451, P = 0.008). Diagnostic performance plot analysis demonstrated that the discrimination threshold value for LVEF that could identify patients prone to reaching the primary endpoint was ≥57.2%. The prevalence of AF or E/e' ratio did not differ significantly between patients with LVEF ≥ 58% and with 40% < LVEF < 58%. CONCLUSION: A higher LVEF is independently related to poor prognosis in patients with HFpEF, in addition to concurrent AF and an elevated E/e' ratio. ACEI/ARB use, in contrast, was associated with improved prognosis, especially with regard to readmission due to HF. CLINICAL TRIAL REGISTRATION: https://www.umin.ac.jp/ctr/index.htm. UNIQUE IDENTIFIER: UMIN000017725.

DOI： 10.1093/ehjci/jeac240

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Association of continuous positive airway pressure therapy on cardiac hypertrophy in patients with sleep apnea comorbid with type 2 diabetes mellitus.

Akeo Ohira, Tadashi Yamakawa, Noriaki Iwahashi, Shunichi Tanaka, Mai Sugiyama, Marina Harada, Masahiro Ichikawa, Tomoaki Akiyama, Kazuki Orime, Yasuo Terauchi

Endocrine journal 70 ( 1 ) 47 - 58 2022.9

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Previous reports indicated the therapeutic effect of chronic continuous positive airway pressure (CPAP) therapy on cardiac hypertrophy due to sleep apnea syndrome. However, little is known for cases involving diabetic complications. This retrospective observational study examined the effects of CPAP therapy on left ventricular hypertrophy (LVH) in patients with obstructive sleep apnea syndrome (OSAS) and type 2 diabetes mellitus (T2DM). For all cases, the observation period was 3 years from the time when the patient was introduced to CPAP therapy. Overall, 123 patients were divided into a good CPAP group (CPAP ≥4 h/day, n = 63) and non-adherence group (CPAP <4 h/day, n = 60). The mean CPAP usage times were 5.58 ± 1.23 and 1.03 ± 1.17 h/day in the good CPAP and non-adherence groups, respectively. Regression tendencies of the thickness of the left ventricular posterior (-0.30 ± 1.19 mm) and interventricular septal walls (-0.48 ± 1.22 mm) were observed in the good CPAP group. Hypertrophic tendencies of the left ventricular posterior wall (+0.59 ± 1.44 mm) and interventricular septal wall thickness (+0.59 ± 1.43) were observed in the non-adherence group. Left ventricular posterior wall thickness (odds ratio, (coefficient: -0.254, p = 0.0376) and interventricular septal wall thickness (coefficient: -0.426, p = 0.0006) were more likely to be greater in the non-adherence group than in the good CPAP group. Patients in the non-adherence group with an apnea hypopnea index ≥30 had increased left ventricular posterior wall thickness (coefficient: -0.263, p = 0.0673) and interventricular septal wall thickness (coefficient: -0.450, p = 0.0011). In conclusion, appropriate CPAP therapy is an effective treatment for LVH in patients with T2DM and OSAS, especially for severe cases.

DOI： 10.1507/endocrj.EJ22-0308

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Influence of the cardio-ankle vascular index on chronic-phase left ventricular dysfunction after ST-segment elevation myocardial infarction. Reviewed International journal

Jin Kirigaya, Noriaki Iwahashi, Takeru Abe, Masaomi Gohbara, Yohei Hanajima, Mutsuo Horii, Yugo Minamimoto, Kozo Okada, Yasushi Matsuzawa, Kiyoshi Hibi, Masami Kosuge, Toshiaki Ebina, Kouichi Tamura, Kazuo Kimura

Journal of hypertension 40 ( 8 ) 1478 - 1486 2022.8

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Authorship：Corresponding author Language：English Publishing type：Research paper (scientific journal)

OBJECTIVE: This study aimed to investigate the possible influence of arterial stiffness assessed by the cardio-ankle vascular index (CAVI) on chronic-phase left ventricular dysfunction in patients with ST-segment elevation myocardial infarction (STEMI). METHODS: A total of 208 consecutive patients with first STEMI (age, 64 ± 11 years; 86% men) who underwent reperfusion therapy within 12 h of onset were enrolled. We analysed arterial stiffness by measuring CAVI in a stable phase after admission and performed two-dimensional echocardiography at baseline and 7 months' follow-up. Subsequently, we assessed left ventricular global longitudinal strain (LV-GLS) to evaluate left ventricular function. A total of 158 (75.9%) patients underwent baseline cardiac magnetic resonance (CMR). We estimated left ventricular infarct size by measuring peak levels of creatine kinase-myocardial band (CK-MB), and CMR-late gadolinium enhancement (LGE). RESULTS: On the basis of the median CAVI value, the patients were allocated into high CAVI (CAVI ≥ 8.575) and low CAVI (CAVI < 8.575) groups. The groups showed no statistically significant differences in LV-GLS at baseline (-13.5% ± 3.1 vs. -13.9% ± 2.7%, P = 0.324). However, LV-GLS was significantly worse in the high CAVI group than in the low-CAVI group at 7 months (-14.0% ± 2.9 vs. -15.6% ± 3.0%, P < 0.001). Stratified by CAVI and peak CK-MB or LGE, the four groups showed significant differences in LV-GLS at 7 months after STEMI (both P < 0.001). Multivariate linear regression analysis with the forced inclusion model showed that CAVI was an independent predictor of LV-GLS at 7 months ( P = 0.015). CONCLUSION: CAVI early after STEMI onset was significantly associated with chronic-phase LV-GLS. In addition, combining CAVI with CK-MB or LGE improves its predictive ability for evaluation of chronic-phase LV-GLS. Thus, the arterial stiffness assessment by CAVI was an important factor related to chronic-phase left ventricular dysfunction after the first STEMI.

DOI： 10.1097/HJH.0000000000003165

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Mechanical dispersion combined with global longitudinal strain estimated by three dimensional speckle tracking in patients with ST elevation myocardial infarction. Reviewed International journal

Noriaki Iwahashi, Jin Kirigaya, Masaomi Gohbara, Takeru Abe, Mutsuo Horii, Yohei Hanajima, Noriko Toya, Hironori Takahashi, Hidekuni Kirigaya, Yugo Minamimoto, Yuichiro Kimura, Kozo Okada, Yasushi Matsuzawa, Kiyoshi Hibi, Masami Kosuge, Toshiaki Ebina, Kouichi Tamura, Kazuo Kimura

International journal of cardiology. Heart & vasculature 40 101028 - 101028 2022.6

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Background: The role of left ventricular (LV) mechanical dispersion estimated after an ST elevation acute myocardial infarction (STEMI) remains unclear. Methods: The study participants were 208 consecutive patients (152 men, age = 72 years) presenting with STEMI for the first time who underwent primary percutaneous coronary intervention (PCI) within 12 h of STEMI onset. Within 48 h of PCI (mean = 24 h), 2D and 3D speckle-tracking echocardiography were performed. The global longitudinal strain (GLS) was calculated using 3D (3D-GLS) and 2D (2D-GLS) speckle tracking. Mechanical dispersion was defined using the standard deviation (SD) of the time to regional peak longitudinal strain (LS) for all 16 segments for both 2D-STE and 3D-STE (2D-LS-SD, 3D-LS-SD). Infarct size was estimated by Tc99m-sestamibi as the total area of < 50% of the uptake area at 2 weeks. The patients were followed up for a longer period of time (median118months) and checked for major adverse cardiac events (MACE: cardiac death, heart failure). Results: During follow-up, 55 patients experienced MACE. The cut-off values were determined using receiver operating characteristic curves. The multivariate analysis revealed that a 3D-LS-SD > 56.7 ms was a significant predictor of MACEs (hazard ratio = 1.991, 95% confidence interval 1.033-3.613, p = 0.03), but 2D-LS-SD > 58.1 ms was not an independent predictor of MACEs (hazard ratio = 1.577, 95% confidence interval 0.815-3.042, p = 0.1). Furthermore, the combination of 3D-GLS and 3D-LS-SD had accurate predictability for MACE, as shown by the Kaplan-Meier curves (log rank, χ2 = 94.1, p < 0.0001). Conclusions: LV mechanical dispersion besides 3D-GLS assessed by 3D-STE immediately after PCI can predict long-term prognosis.

DOI： 10.1016/j.ijcha.2022.101028

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Prognostic Significance of the Combination of Left Atrial Reservoir Strain and Global Longitudinal Strain Immediately After Onset of ST-Elevation Acute Myocardial Infarction.

Noriaki Iwahashi, Masaomi Gohbara, Jin Kirigaya, Takeru Abe, Mutsuo Horii, Yohei Hanajima, Noriko Toya, Hironori Takahashi, Yuichiro Kimura, Yugo Minamimoto, Kozo Okada, Yasushi Matsuzawa, Kiyoshi Hibi, Masami Kosuge, Toshiaki Ebina, Kouichi Tamura, Kazuo Kimura

Circulation journal : official journal of the Japanese Circulation Society 86 ( 10 ) 1499 - 1508 2022.5

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BACKGROUND: The role of left atrial (LA) function in the long-term prognosis of ST-elevation acute myocardial infarction (STEMI) is still unclear.Methods and Results: Percutaneous coronary intervention (PCI) was performed in 433 patients with the first episode of STEMI within 12 h of onset. The patients underwent echocardiography 24 h after admission. LA reservoir strain and other echocardiographic parameters were analyzed. Follow up was performed for up to 10 years (mean duration, 91 months). The primary endpoint was major adverse cardiovascular events (MACE): cardiac death or hospitalization due to heart failure (HF). MACE occurred in 90 patients (20%) during the follow-up period. Multivariate Cox hazard analyses showed LA reservoir strain, global longitudinal strain (GLS), age and maximum B-type natriuretic peptide (BNP) were the significant predictors of MACE. Kaplan-Meier curves demonstrated that LA reservoir strain <25.8% was a strong predictor (Log rank, χ2=76.7, P<0.0001). Net reclassification improvement (NRI) demonstrated that adding LA reservoir strain had significant incremental effect on the conventional parameters (NRI and 95% CI: 0.24 [0.11-0.44]) . When combined with GLS >-11.5%, the patients with LA reservoir strain <25.8% were found to be at extremely high risk for MACE (Log rank, χ2=126.3, P<0.0001). CONCLUSIONS: LA reservoir strain immediately after STEMI onset was a significant predictor of poor prognosis in patients, especially when combined with GLS.

DOI： 10.1253/circj.CJ-21-0907

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Admission free-fatty acid level is a predictor of the mid-term worsening renal function in patients with ST-segment elevation myocardial infarction.

Masaomi Gohbara, Noriaki Iwahashi, Kozo Okada, Yugo Minamimoto, Yasushi Matsuzawa, Masaaki Konishi, Kiyoshi Hibi, Masami Kosuge, Toshiaki Ebina, Teruyasu Sugano, Toshiyuki Ishikawa, Kouichi Tamura, Kazuo Kimura

Heart and vessels 37 ( 5 ) 720 - 729 2022.5

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DOI： 10.1007/s00380-021-01982-0

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Clinical Usefulness of the Serial Examination of Three-Dimensional Global Longitudinal Strain After the Onset of ST-Elevation Acute Myocardial Infarction

Noriaki Iwahashi, Mutsuo Horii, Jin Kirigaya, Takeru Abe, Masaomi Gohbara, Noriko Toya, Yohei Hanajima, Hironori Takahashi, Yugo Minamimoto, Yuichiro Kimura, Kozo Okada, Yasushi Matsuzawa, Kiyoshi Hibi, Masami Kosuge, Toshiaki Ebina, Kouichi Tamura, Kazuo Kimura

CIRCULATION JOURNAL 86 ( 4 ) 611 - + 2022.4

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Language：English Publishing type：Research paper (scientific journal) Publisher：JAPANESE CIRCULATION SOC

Background: Two-dimensional (2D) and three-dimensional (3D) speckle tracking echocardiography (STE) after ST-elevation acute myocardial infarction (STEMI) can predict the prognosis. This study investigated the clinical significance of a serial 3D-STE can predict the prognosis after onset of STEMI.Methods and Results: This study enrolled 272 patients (mean age, 65 years) with first-time STEMI treated with reperfusion therapy. At 24h after admission, standard 2D echocardiography and 3D full-volume imaging were performed, and 2D-STE and 3D-STE were calculated. Within 1 year, 19 patients who experienced major adverse cardiac events (MACE; cardiac death, heart failure requiring hospitalization) were excluded. Among the 253 patients, 248 were examined with follow-up echocardiography. The patients were followed up for a median of 108 months (interquartile range: 96-129 months). The primary endpoint was the occurrence of a MACE; 45 patients experienced MACEs. Receiver operating characteristic curves and Cox hazard multivariate analysis showed that the 2D-global longitudinal strain (GLS) and 3D-GLS at 1-year indices were significant predictors of MACE. The Kaplan-Meier curve demonstrated that a 3D-GLS of >-13.1 was an independent predictor for MACE (log-rank x(2) =165.5, P<0.0001). The deterioration of 3D-GLS at 1 year was a significant prognosticator (log-rank X-2 =36.7, P<0.0001).Conclusions: The deterioration of 3D-GLS measured by STE at 1 year after the onset of STEMI is the strongest predictor of long-term prognosis.

DOI： 10.1253/circj.CJ-21-0815

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Worsening Dyspnea in Patients With Idiopathic Portal Hypertension. International journal

Noriaki Iwahashi, Mutsuo Horii, Kouichi Tamura, Kazuo Kimura

Chest 161 ( 4 ) e245-e248 2022.4

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DOI： 10.1016/j.chest.2021.05.077

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Clinical Usefulness of the Serial Examination of Three-Dimensional Global Longitudinal Strain After the Onset of ST-Elevation Acute Myocardial Infarction.

Noriaki Iwahashi, Mutsuo Horii, Jin Kirigaya, Takeru Abe, Masaomi Gohbara, Noriko Toya, Yohei Hanajima, Hironori Takahashi, Yugo Minamimoto, Yuichiro Kimura, Kozo Okada, Yasushi Matsuzawa, Kiyoshi Hibi, Masami Kosuge, Toshiaki Ebina, Kouichi Tamura, Kazuo Kimura

Circulation journal : official journal of the Japanese Circulation Society 86 ( 4 ) 611 - 619 2022.3

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BACKGROUND: Two-dimensional (2D) and three-dimensional (3D) speckle tracking echocardiography (STE) after ST-elevation acute myocardial infarction (STEMI) can predict the prognosis. This study investigated the clinical significance of a serial 3D-STE can predict the prognosis after onset of STEMI.Methods and Results:This study enrolled 272 patients (mean age, 65 years) with first-time STEMI treated with reperfusion therapy. At 24 h after admission, standard 2D echocardiography and 3D full-volume imaging were performed, and 2D-STE and 3D-STE were calculated. Within 1 year, 19 patients who experienced major adverse cardiac events (MACE; cardiac death, heart failure requiring hospitalization) were excluded. Among the 253 patients, 248 were examined with follow-up echocardiography. The patients were followed up for a median of 108 months (interquartile range: 96-129 months). The primary endpoint was the occurrence of a MACE; 45 patients experienced MACEs. Receiver operating characteristic curves and Cox hazard multivariate analysis showed that the 2D-global longitudinal strain (GLS) and 3D-GLS at 1-year indices were significant predictors of MACE. The Kaplan-Meier curve demonstrated that a 3D-GLS of >-13.1 was an independent predictor for MACE (log-rank χ2=165.5, P<0.0001). The deterioration of 3D-GLS at 1 year was a significant prognosticator (log-rank χ2=36.7, P<0.0001). CONCLUSIONS: The deterioration of 3D-GLS measured by STE at 1 year after the onset of STEMI is the strongest predictor of long-term prognosis.

DOI： 10.1253/circj.CJ-21-0815

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A Fatal Case of Takotsubo Cardiomyopathy Secondary to Refractory Hypoglycemia in Severe Starvation: An Autopsy Case Report. International journal

Jin Kirigaya, Noriaki Iwahashi, Reiko Tanaka, Yoshiaki Inayama, Ichiro Takeuchi

Cureus 14 ( 3 ) e23287 2022.3

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DOI： 10.7759/cureus.23287

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Efficacy and Safety of Early Initiation of Eplerenone Treatment in Patients with Acute Heart Failure (EARLIER trial): a multicentre, randomized, double-blind, placebo-controlled trial. International journal

Masanori Asakura, Shin Ito, Takahisa Yamada, Yoshihiko Saito, Kazuo Kimura, Akira Yamashina, Atsushi Hirayama, Youichi Kobayashi, Akihisa Hanatani, Mitsuru Tsujimoto, Satoshi Yasuda, Yukio Abe, Yorihiko Higashino, Yodo Tamaki, Hiroshi Sugino, Hiroyuki Niinuma, Yoshitaka Okuhara, Toshimi Koitabashi, Shin-Ichi Momomura, Kuniya Asai, Akihiro Nomura, Hiroya Kawai, Yasuhiro Satoh, Tsutomu Yoshikawa, Ken-Ichi Hirata, Yoshiaki Yokoi, Jun Tanaka, Yoshisato Shibata, Yasuhiro Maejima, Shunsuke Tamaki, Hiroyuki Kawata, Noriaki Iwahashi, Masatake Kobayashi, Yoshiharu Higuchi, Akiko Kada, Haruko Yamamoto, Masafumi Kitakaze

European heart journal. Cardiovascular pharmacotherapy 8 ( 2 ) 108 - 117 2022.2

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Language：English Publishing type：Research paper (scientific journal) Publisher：OXFORD UNIV PRESS

AIMS: A mineralocorticoid receptor antagonist (MRA) is effective in patients with chronic heart failure; however, the effects of the early initiation of an MRA in patients with acute heart failure (AHF) have not been elucidated. METHODS AND RESULTS: In this multicentre, randomized, double-blind, placebo-controlled, parallel-group study, we focused on the safety and effectiveness of the treatment with eplerenone, a selective MRA in 300 patients with AHF, that is, 149 in the eplerenone group and 151 in the placebo group in 27 Japanese institutions. The key inclusion criteria were (i) patients aged 20 years or older and (ii) those with left ventricular ejection fraction of ≤40%. The primary outcome was a composite of cardiac death or first re-hospitalization due to cardiovascular disease within 6 months. The mean age of the participants was 66.8 years, 27.3% were women, and the median levels of brain natriuretic peptide were 376.0 pg/mL. The incidences of the primary outcome were 19.5% in the eplerenone group and 17.2% in the placebo group [hazard ratio (HR): 1.09, 95% confidence interval (CI): 0.642-1.855]. In prespecified secondary outcomes, HR for the composite endpoint, cardiovascular death, or first re-hospitalization due to heart failure within 6 months was 0.55 (95% CI: 0.213-1.434). The safety profile for eplerenone was as expected. CONCLUSION: The early initiation of eplerenone in patients with AHF could safely be utilized. The reduction of the incidence of a composite of cardiovascular death or first re-hospitalization for cardiovascular diseases by eplerenone is inconclusive because of inadequate power.

DOI： 10.1093/ehjcvp/pvaa132

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Clinical usefulness of left ventricular outflow tract velocity time integral for heart failure with reduced ejection fraction with rapid atrial fibrillation during landiolol treatment. International journal

Noriaki Iwahashi, Jin Kirigaya, Takeru Abe, Mutsuo Horii, Hironori Takahashi, Yohei Hanajima, Yuichiro Kimura, Yugo Minamimoto, Kozo Okada, Yasushi Matsuzawa, Kiyoshi Hibi, Masami Kosuge, Toshiaki Ebina, Kouichi Tamura, Kazuo Kimura

Journal of cardiology 79 ( 1 ) 21 - 29 2022.1

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BACKGROUND: Landiolol enables us to treat the patients with rapid atrial fibrillation (AF) with acute decompensated heart failure (ADHF) efficiently. We sought to determine the role of echocardiography in predicting the prognosis. METHODS: Among 314 patients, a total 115 ADHF patients with reduced ejection fraction and rapid AF were enrolled. They received landiolol treatment to decrease the heart rate (HR) to <110 bpm and change HR (ΔHR) of >20% within 24 h. The dose of landiolol was increased every 2 h; then, we performed echocardiography repeatedly, at baseline, 2 h, and 24h. We followed the patients after discharge for 180 days, and checked cardiac death and HF hospitalization as major adverse cardiac events (MACE). RESULTS: During initial hospitalization, 5 patients (4%) died. During 180 days after discharge, 19 (16%) out of 115 patients experienced MACE (2 cardiac death, 17 HF rehospitalization, 5 in-hospital death). Multivariate analysis showed that the change in left ventricular outflow tract-velocity time integral (LVOT-VTI) at 2 h was the most significant predictor for MACE (hazard ratio =1.21, 95% confidence interval: 1.10-1.83, p=0.0001). Kaplan-Meier curves demonstrated the patients with deteriorated LVOT-VTI at minimum dose landiolol suggested the high-risk patients for MACE (χ2=30.9, p<0.0001). CONCLUSIONS: During landiolol treatment, the patients with deteriorated LVOT-VTI predicted the poor prognosis. We may detect the high-risk patients by two-point echocardiography. UMIN000020084. Registered 1 November 2013 - prospective study https://upload.umin.ac.jp/cgi-open-bin/ctr/ctr.cgi?function=brows&action=brows&type=summary&language=J&recptno=R000023203.

DOI： 10.1016/j.jjcc.2021.09.008

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Clinical usefulness of left ventricular outflow tract velocity time integral for heart failure with reduced ejection fraction with rapid atrial fibrillation during landiolol treatment

Noriaki Iwahashi, Jin Kirigaya, Takeru Abe, Mutsuo Horii, Hironori Takahashi, Yohei Hanajima, Yuichiro Kimura, Yugo Minamimoto, Kozo Okada, Yasushi Matsuzawa, Kiyoshi Hibi, Masami Kosuge, Toshiaki Ebina, Kouichi Tamura, Kazuo Kimura

JOURNAL OF CARDIOLOGY 79 ( 1 ) 21 - 29 2022.1

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Background: Landiolol enables us to treat the patients with rapid atrial fibrillation (AF) with acute de compensated heart failure (ADHF) efficiently. We sought to determine the role of echocardiography in predicting the prognosis.Methods: Among 314 patients, a total 115 ADHF patients with reduced ejection fraction and rapid AF were enrolled. They received landiolol treatment to decrease the heart rate (HR) to < 110 bpm and change HR (Delta HR) of > 20% within 24 h. The dose of landiolol was increased every 2 h; then, we performed echocardiography repeatedly, at baseline, 2 h, and 24h. We followed the patients after discharge for 180 days, and checked cardiac death and HF hospitalization as major adverse cardiac events (MACE).Results: During initial hospitalization, 5 patients (4%) died. During 180 days after discharge, 19 (16%) out of 115 patients experienced MACE (2 cardiac death, 17 HF rehospitalization, 5 in-hospital death). Multivariate analysis showed that the change in left ventricular outflow tract-velocity time integral (LVOT-VTI) at 2 h was the most significant predictor for MACE (hazard ratio = 1.21, 95% confidence interval: 1.10-1.83, p = 0.0001). Kaplan-Meier curves demonstrated the patients with deteriorated LVOT-VTI at minimum dose landiolol suggested the high-risk patients for MACE (chi(2) = 30.9, p < 0.0 0 01).Conclusions: During landiolol treatment, the patients with deteriorated LVOT-VTI predicted the poor prognosis. We may detect the high-risk patients by two-point echocardiography. (C) 2021 Japanese College of Cardiology. Published by Elsevier Ltd. All rights reserved.

DOI： 10.1016/j.jjcc.2021.09.008

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Impact of three-dimensional global longitudinal strain for patients with acute myocardial infarction

Noriaki Iwahashi, Jin Kirigaya, Takeru Abe, Mutsuo Horii, Noriko Toya, Yohei Hanajima, Hironori Takahashi, Eiichi Akiyama, Kozo Okada, Yasushi Matsuzawa, Nobuhiko Maejima, Kiyoshi Hibi, Masami Kosuge, Toshiaki Ebina, Kouichi Tamura, Kazuo Kimura

EUROPEAN HEART JOURNAL-CARDIOVASCULAR IMAGING 22 ( 12 ) 1413 - 1424 2021.12

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Aims In patients with ST-segment elevation myocardial infarction (STEMI), predicting left ventricular (LV) remodelling (LVR) and prognosis is important. We explored the clinical usefulness of three-dimensional (3D) speckle-tracking echocardiography to predict LVR and prognosis in STEMI.Methods and results The study group comprised 255 first STEMI patients (65 years; 210 men) treated with primary percutaneous coronary intervention between April 2008 and May 2012 at Yokohama City University Medical Center. Baseline global longitudinal strain (GLS) was measured with two-dimensional (2D) and 3D speckle-tracking echocardiography. Within 48 of admission, standard 2D echocardiography and 3D full-volume imaging were performed, and 2D-GLS and 3D-GLS were calculated. Infarct size was estimated by Tc-99m-sestamibi single-photon emission computed tomography. Echocardiography was performed at 1 year repeatedly in 239 patients. The primary endpoint was LVR, defined as an increase of 20% of LV end-diastolic volume index and major adverse cardiac and cerebrovascular events (MACE: cardiac death, non-fatal MI, heart failure, and ischaemic stroke) at 1 year, and the secondary endpoint was cardiac death and heart failure. Patients were followed for 1 year; 64, 25, and 16 patients experienced LVR, MACE, and the secondary endpoint, respectively. Multivariate analysis revealed that 3D-GLS was the strongest predictor of LVR (odds ratio = 1.437, 95% CI: 1.047-2.257, P = 0.02), MACE (odds ratio = 1.443, 95% CI: 1.240-1.743, P = 0.0002), and the secondary end point (odds ratio = 1.596, 95% CI: 1.17-1.56, P < 0.0001). Receiver-operating characteristic curve analysis showed that 3D-GLS was superior to 2D-GLS in predicting LVR and 1-year prognosis.Conclusion 3D-GLS obtained immediately after STEMI is independently associated with LVR and 1-year prognosis.

DOI： 10.1093/ehjci/jeaa241

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Global Strain Measured by Three-Dimensional Speckle Tracking Echocardiography Is a Useful Predictor for 10-Year Prognosis After a First ST-Elevation Acute Myocardial Infarction

Noriaki Iwahashi, Jin Kirigaya, Masaomi Gohbara, Takeru Abe, Mutsuo Horii, Yohei Hanajima, Noriko Toya, Hironori Takahashi, Yugo Minamimoto, Yuichiro Kimura, Eiichi Akiyama, Kozo Okada, Yasushi Matsuzawa, Nobuhiko Maejima, Kiyoshi Hibi, Masami Kosuge, Toshiaki Ebina, Kouichi Tamura, Kazuo Kimura

CIRCULATION JOURNAL 85 ( 10 ) 1735 - 1743 2021.10

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Background: Three-dimensional (3D) speckle tracking echocardiography (STE) after ST-elevation acute myocardial infarction (STEMI) is associated with left ventricular (LV) remodeling and 1-year prognosis. This study investigated the clinical significance of 3D-STE in predicting the long-term prognosis of patients with STEMI.Methods and Results: A total of 270 patients (mean age 64.6 years) with first-time STEMI treated with reperfusion therapy were enrolled. At 24h after admission, standard 2D echocardiography and 3D full-volume imaging were performed, and 2D-STE and 3D-STE were calculated. Patients were followed up for a median of 119 months (interquartile range: 96-129 months). The primary endpoint was occurrence of a major adverse cardiac event (MACE: cardiac death, heart failure with hospitalization), and 64 patients experienced MACEs. Receiver operating characteristic curves and Cox hazard multivariate analysis showed that the 3D-STE indices were stronger predictors of MACE compared with those of 2D-STE. Additionally, 3D-global longitudinal strain (GLS) was the strongest predictor for MACE followed by 3D-global circumferential strain (GCS). The Kaplan-Meier curve demonstrated that 3D-GLS >-11.0 was an independent predictor for MACE (log-rank X-2=132.2, P<0.0001). When combined with 3D-GCS >-18.3, patients with higher values of 3D-GLS and 3D-GCS were found to be at extremely high risk for MACE.Conclusions: Global strain measured by 3D-STE immediately after the onset of STEMI is a clinically significant predictor of 10-year prognosis.

DOI： 10.1253/circj.CJ-21-0183

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Global Strain Measured by Three-Dimensional Speckle Tracking Echocardiography Is a Useful Predictor for 10-Year Prognosis After a First ST-Elevation Acute Myocardial Infarction.

Noriaki Iwahashi, Jin Kirigaya, Masaomi Gohbara, Takeru Abe, Mutsuo Horii, Yohei Hanajima, Noriko Toya, Hironori Takahashi, Yugo Minamimoto, Yuichiro Kimura, Eiichi Akiyama, Kozo Okada, Yasushi Matsuzawa, Nobuhiko Maejima, Kiyoshi Hibi, Masami Kosuge, Toshiaki Ebina, Kouichi Tamura, Kazuo Kimura

Circulation journal : official journal of the Japanese Circulation Society 85 ( 10 ) 1735 - 1743 2021.6

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BACKGROUND: Three-dimensional (3D) speckle tracking echocardiography (STE) after ST-elevation acute myocardial infarction (STEMI) is associated with left ventricular (LV) remodeling and 1-year prognosis. This study investigated the clinical significance of 3D-STE in predicting the long-term prognosis of patients with STEMI.Methods and Results:A total of 270 patients (mean age 64.6 years) with first-time STEMI treated with reperfusion therapy were enrolled. At 24 h after admission, standard 2D echocardiography and 3D full-volume imaging were performed, and 2D-STE and 3D-STE were calculated. Patients were followed up for a median of 119 months (interquartile range: 96-129 months). The primary endpoint was occurrence of a major adverse cardiac event (MACE: cardiac death, heart failure with hospitalization), and 64 patients experienced MACEs. Receiver operating characteristic curves and Cox hazard multivariate analysis showed that the 3D-STE indices were stronger predictors of MACE compared with those of 2D-STE. Additionally, 3D-global longitudinal strain (GLS) was the strongest predictor for MACE followed by 3D-global circumferential strain (GCS). The Kaplan-Meier curve demonstrated that 3D-GLS >-11.0 was an independent predictor for MACE (log-rank χ2=132.2, P<0.0001). When combined with 3D-GCS >-18.3, patients with higher values of 3D-GLS and 3D-GCS were found to be at extremely high risk for MACE. CONCLUSIONS: Global strain measured by 3D-STE immediately after the onset of STEMI is a clinically significant predictor of 10-year prognosis.

DOI： 10.1253/circj.CJ-21-0183

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Optimal timing of echocardiography for heart failure inpatients in Japanese institutions: OPTIMAL Study

Hidekazu Tanaka, Yosuke Nabeshima, Tetsuji Kitano, Sakura Nagumo, Miki Tsujiuchi, Mio Ebato, Hiroyuki Mataki, Masanori Takada, Taichi Hayashi, Daisuke Sato, Yoko Miyasaka, Keiko Araki, Noriaki Iwahashi, Masaaki Takeuchi, Satoshi Nakatani

ESC HEART FAILURE 7 ( 6 ) 4213 - 4221 2020.12

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Language：English Publishing type：Research paper (scientific journal) Publisher：WILEY PERIODICALS, INC

Aims Guidelines for the diagnosis and treatment of acute and chronic heart failure (HF) provided by the European Society of Cardiology state that echocardiography is recommended for the assessment of the myocardial structure and function of subjects with suspected HF including HF with reduced (HFrEF), mid-range (HFmrEF), and preserved ejection fraction (HFpEF) as class I of recommendation and level C of evidence. However, the impact of timing of echocardiography on survival for hospitalized HF patients or the prevalence of echocardiography during their stay has not yet been fully investigated. Therefore, we designed and conducted a prospective multicentre study, Optimal Timing of Echocardiography for Heart Failure Inpatients in Japanese Institutions (OPTIMAL) study, to investigate and evaluate the prevalence of echocardiography during the in-hospital stay of HF patients, and the impact of timing of echocardiography on their survival.Methods and results OPTIMAL was based on a nationwide, prospective, multicentre registry at 10 institutions in Japan endorsed by the Japanese Society of Echocardiography. A total of 601 patients hospitalized with HF were enrolled between August 2016 and July 2018 at the participating centres. Their mean age was 73.9 +/- 13.0 years, left ventricular ejection fraction was 37.0% (26.0-50.0), and 256 patients (42.6%) were female. Admission echocardiography (admission echo) was categorized as either standard or point-of-care echocardiography performed within 3 days of admission, as was pre-discharge echocardiography (pre-discharge echo) within 3 days of discharge. The primary endpoint was defined as cardiovascular death over a median follow-up period of 18.9 months (9.3-26.5 months). Admission echo was performed for 476 patients (79.2%) and pre-discharge echo for 216 patients (35.9%). The primary endpoint of cardiovascular death occurred in 65 patients (10.8%). Kaplan-Meier curve findings indicated that survival of patients with pre-discharge echo was significantly better than that of patients without it (log-rankP < 0.001), and the same findings were obtained for patients with HFrEF, HFmrEF, and HFpEF. However, survival of patients with and without admission echo was similar (log-rankP = 0.33).Conclusions This OPTIMAL study prospectively showed the importance of pre-discharge echo for hospitalized HF patients. Careful attention is needed regarding the haemodynamic status of HF patients by administering pre-discharge echo to avoid HF re-hospitalization after discharge, and pre-discharge echo may provide additional information for deciding the appropriate discharge time. Our findings may thus offer a new insight into the management of hospitalized HF patients.

DOI： 10.1002/ehf2.13050

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Prognostic Significance of a Combination of QRS Score and E/e ' Obtained 2 Weeks After the Onset of ST-Elevation Myocardial Infarction

Noriaki Iwahashi, Masaomi Gohbara, Jin Kirigaya, Takeru Abe, Mutsuo Horii, Hironori Takahashi, Masami Kosuge, Yohei Hanajima, Eiichi Akiyama, Kozo Okada, Yasushi Matsuzawa, Nobuhiko Maejima, Kiyoshi Hibi, Toshiaki Ebina, Kouichi Tamura, Kazuo Kimura

CIRCULATION JOURNAL 84 ( 11 ) 1965 - + 2020.11

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Background: The early mitral inflow velocity to mitral early diastolic velocity ratio (E/e') and electrocardiogram (ECG) determination of QRS score are useful for risk stratification in patients with ST-elevation myocardial infarction (STEMI).Methods and Results: In this study, 420 consecutive patients (357 male; mean [+/- SD] age 63.6 +/- 12.2 years) with first-time STEMI who successfully underwent primary percutaneous coronary intervention within 12 h of symptom onset were followed-up for 5 years (median follow-up 67 months). Echocardiography, ECG, and blood samples were obtained 2 weeks after onset. Infarct size was estimated by the QRS score after 2 weeks (QRS-2wks) and creatine phosphokinase-MB concentrations (peak and area under the curve). The primary endpoint was death from cardiac causes or rehospitalization for heart failure (HF). During follow-up, 21 patients died of cardiac causes and 62 had HF. Multivariate Cox proportional hazard analysis showed that mean E/e ' (hazard ratio [HR] 1.152; 95% confidence interval [CI] 1.088-1.215; P<0.0001), QRS-2wks (HR 1.153; 95% CI 1.057-1.254; P<0.0001), and hypertension (HR 1.702; 95% CI 1.040-2.888; P=0.03) were independent predictors of the primary endpoint. Kaplan-Meier curve analysis showed that patients with QRS-2wks >4 and mean E/e ' >14 were at an extremely high risk of cardiac death or HF (log rank, chi 2=116.3, P<0.0001).Conclusions: In patients with STEMI, a combination of QRS-2wks and mean E/e' was a simple but useful predictor of cardiac death and HF.

DOI： 10.1253/circj.CJ-20-0486

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Prognostic Significance of a Combination of QRS Score and E/e' Obtained 2 Weeks After the Onset of ST-Elevation Myocardial Infarction.

Noriaki Iwahashi, Masaomi Gohbara, Jin Kirigaya, Takeru Abe, Mutsuo Horii, Hironori Takahashi, Masami Kosuge, Yohei Hanajima, Eiichi Akiyama, Kozo Okada, Yasushi Matsuzawa, Nobuhiko Maejima, Kiyoshi Hibi, Toshiaki Ebina, Kouichi Tamura, Kazuo Kimura

Circulation journal : official journal of the Japanese Circulation Society 84 ( 11 ) 1965 - 1973 2020.10

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BACKGROUND: The early mitral inflow velocity to mitral early diastolic velocity ratio (E/e') and electrocardiogram (ECG) determination of QRS score are useful for risk stratification in patients with ST-elevation myocardial infarction (STEMI).Methods and Results:In this study, 420 consecutive patients (357 male; mean [±SD] age 63.6±12.2 years) with first-time STEMI who successfully underwent primary percutaneous coronary intervention within 12 h of symptom onset were followed-up for 5 years (median follow-up 67 months). Echocardiography, ECG, and blood samples were obtained 2 weeks after onset. Infarct size was estimated by the QRS score after 2 weeks (QRS-2wks) and creatine phosphokinase-MB concentrations (peak and area under the curve). The primary endpoint was death from cardiac causes or rehospitalization for heart failure (HF). During follow-up, 21 patients died of cardiac causes and 62 had HF. Multivariate Cox proportional hazard analysis showed that mean E/e' (hazard ratio [HR] 1.152; 95% confidence interval [CI] 1.088-1.215; P<0.0001), QRS-2wks (HR 1.153; 95% CI 1.057-1.254; P<0.0001), and hypertension (HR 1.702; 95% CI 1.040-2.888; P=0.03) were independent predictors of the primary endpoint. Kaplan-Meier curve analysis showed that patients with QRS-2wks >4 and mean E/e' >14 were at an extremely high risk of cardiac death or HF (log rank, χ2=116.3, P<0.0001). CONCLUSIONS: In patients with STEMI, a combination of QRS-2wks and mean E/e' was a simple but useful predictor of cardiac death and HF.

DOI： 10.1253/circj.CJ-20-0486

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Impact of three-dimensional global longitudinal strain for patients with acute myocardial infarction. International journal

Noriaki Iwahashi, Jin Kirigaya, Takeru Abe, Mutsuo Horii, Noriko Toya, Yohei Hanajima, Hironori Takahashi, Eiichi Akiyama, Kozo Okada, Yasushi Matsuzawa, Nobuhiko Maejima, Kiyoshi Hibi, Masami Kosuge, Toshiaki Ebina, Kouichi Tamura, Kazuo Kimura

European heart journal. Cardiovascular Imaging 2020.9

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AIMS: In patients with ST-segment elevation myocardial infarction (STEMI), predicting left ventricular (LV) remodelling (LVR) and prognosis is important. We explored the clinical usefulness of three-dimensional (3D) speckle-tracking echocardiography to predict LVR and prognosis in STEMI. METHODS AND RESULTS: The study group comprised 255 first STEMI patients (65 years; 210 men) treated with primary percutaneous coronary intervention between April 2008 and May 2012 at Yokohama City University Medical Center. Baseline global longitudinal strain (GLS) was measured with two-dimensional (2D) and 3D speckle-tracking echocardiography. Within 48 of admission, standard 2D echocardiography and 3D full-volume imaging were performed, and 2D-GLS and 3D-GLS were calculated. Infarct size was estimated by 99mTc-sestamibi single-photon emission computed tomography. Echocardiography was performed at 1 year repeatedly in 239 patients. The primary endpoint was LVR, defined as an increase of 20% of LV end-diastolic volume index and major adverse cardiac and cerebrovascular events (MACE: cardiac death, non-fatal MI, heart failure, and ischaemic stroke) at 1 year, and the secondary endpoint was cardiac death and heart failure. Patients were followed for 1 year; 64, 25, and 16 patients experienced LVR, MACE, and the secondary endpoint, respectively. Multivariate analysis revealed that 3D-GLS was the strongest predictor of LVR (odds ratio = 1.437, 95% CI: 1.047-2.257, P = 0.02), MACE (odds ratio = 1.443, 95% CI: 1.240-1.743, P = 0.0002), and the secondary end point (odds ratio = 1.596, 95% CI: 1.17-1.56, P < 0.0001). Receiver-operating characteristic curve analysis showed that 3D-GLS was superior to 2D-GLS in predicting LVR and 1-year prognosis. CONCLUSION: 3D-GLS obtained immediately after STEMI is independently associated with LVR and 1-year prognosis.

DOI： 10.1093/ehjci/jeaa241

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Impact of Cardio-Ankle Vascular Index on Long-Term Outcome in Patients with Acute Coronary Syndrome. Reviewed

Jin Kirigaya, Noriaki Iwahashi, Hironori Tahakashi, Yugo Minamimoto, Masaomi Gohbara, Takeru Abe, Eiichi Akiyama, Kozo Okada, Yasushi Matsuzawa, Nobuhiko Maejima, Kiyoshi Hibi, Masami Kosuge, Toshiaki Ebina, Kouichi Tamura, Kazuo Kimura

Journal of atherosclerosis and thrombosis 27 ( 7 ) 657 - 668 2020.7

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DOI： 10.5551/jat.51409

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Three Dimensional Strain Imaging is Superior to Two Dimensional Strain Imaging to Predict Adverse Left Ventricular Remodeling and Short-Term Prognosis After ST-segment-Elevation Myocardial Infarction

Noriaki Iwahashi, Jin Kirigaya, Kozo Okada, Eiichi Akiyama, Yasushi Matsuzawa, Nobuhiko Maejima, Kiyoshi Hibi, Masami Kosuge, Toshiaki Ebina, Kouichi Tamura, Kazuo Kimura

CIRCULATION 140 2019.11

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Glycemic Variability is a Strong Predictor in Patients With Impaired Glucose Tolerance After First Episode of Acute Coronary Syndrome

Yohei Hanajima, Noriaki Iwahashi, Jin Kirigaya, Hironori Takahashi, Yugo Minamimoto, Eiichi Akiyama, Kozo Okada, Nobuhiko Maejima, Yasushi Matsuzawa, Kiyoshi Hibi, Masami Kosuge, Toshiaki Ebina, Kouichi Tamura, Kazuo Kimura

CIRCULATION 140 2019.11

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LVOT-VTI×平均BPは急性心房細動に対する血行動態の状態を評価するための有用な心エコー指標である(LVOT-VTI×Mean BP is The Useful Echocardiographic Index to Evaluate the Hemodynamic Status for Rapid Atrial Fibrillation)

岩橋徳明, 桐ヶ谷仁, 高橋広軌, 堀井睦夫, 木村裕一郎, 秋山英一, 岡田興造, 松澤泰志, 小西正紹, 前島信彦, 日比潔, 小菅雅美, 海老名俊明, 田村功一, 木村一雄

日本循環器学会学術集会抄録集 83回 PJ021 - 3 2019.3

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持続的血糖モニタリングシステムで検出された急性期低血糖はSTEMI患者における不良な予後を予測する(Hypoglycemia in Acute Phase Detected by Contentious Glucose Monitoring System can Predict Poor Prognosis in Patients with STEMI)

高橋広軌, 岩橋徳明, 桐ヶ谷仁, 南本祐吾, 秋山英一, 岡田興造, 松澤泰志, 小西正紹, 前島信彦, 日比潔, 小菅雅美, 海老名俊明, 田村功一, 木村一雄

日本循環器学会学術集会抄録集 83回 PJ018 - 3 2019.3

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Urgent Control of Rapid Atrial Fibrillation Using Landiolol in Patients With Heart Failure and Severely Reduced Ejection Fraction in Acute Decompensated Heart Failure

Noriaki Iwahashi, Hironori Takahashi, Eiichi Akiyama, Kozo Okada, Yasushi Matsuzawa, Masaaki Konishi, Nobuhiko Maejima, Kiyoshi Hibi, Masami Kosuge, Toshiaki Ebina, Koichi Tamura, Kazuo Kimura

CIRCULATION 138 2018.11

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The Impact of Arterial Stiffness on Heart Failure at Admission in Patients With Acute Myocardial Infarction

Jin Kirigaya, Noriaki Iwahashi, Yasushi Matsuzawa, Kouzo Okada, Masaaki Konishi, Nobuhiko Maejima, Masami Kosuge, Kiyoshi Hibi, Kazuo Kimura, Kouichi Tamura

CIRCULATION 138 2018.11

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Global Strain Estimated by 3D Speckle Tracking Combined With E/E' is the Strongest Predictor in Patients With STEMI

Noriaki Iwahashi, Hironori Takahashi, Eiichi Akiyama, Kozo Okada, Yasushi Matsuzawa, Masaaki Konishi, Nobuhiko Maejima, Kiyoshi Hibi, Masami Kosuge, Toshiaki Ebina, Koichi Tamura, Kazuo Kimura

CIRCULATION 138 2018.11

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Glycemic variability determined with a continuous glucose monitoring system can predict prognosis after acute coronary syndrome

Hironori Takahashi, Noriaki Iwahashi, Jin Kirigaya, Shunsuke Kataoka, Yugo Minamimoto, Masaomi Gohbara, Takeru Abe, Kozo Okada, Yasushi Matsuzawa, Masaaki Konishi, Nobuhiko Maejima, Kiyoshi Hibi, Masami Kosuge, Toshiaki Ebina, Kouichi Tamura, Kazuo Kimura

CARDIOVASCULAR DIABETOLOGY 17 2018.8

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Language：English Publishing type：Research paper (scientific journal) Publisher：BMC

Background: Impaired glucose metabolism is an established risk factor for coronary artery disease. Previous studies revealed that glycemic variability (GV) is also important for glucose metabolism in patients with acute coronary syndrome (ACS). We explored the association between GV and prognosis in patients with ACS.Methods: A total of 417 patients with ACS who received reperfusion wore a continuous glucose monitoring system (CGMS) in a stable phase after admission and were monitored for at least 24 consecutive h. The mean amplitude of glycemic excursion (MAGE) was calculated as a marker of GV. We divided into two groups based on the highest tertile levels of MAGE (MAGE =52 mg/dl). The groups were followed up for a median of 39 months [IQR 24-50 months]. The primary endpoint was the incidence of major adverse cardiovascular and cerebrovascular events (MACCE).Result: During follow-up, 66 patients experienced MACCE (5 patients had cardiovascular death, 14 had recurrence of ACS, 27 had angina requiring revascularization, 8 had acute decompensated heart failure, and 16 had a stroke). MACCE was more frequently observed in the high MAGE group (23.5% vs. 11.6%, p = 0.002). In multivariate analysis, high MAGE was an independent predictive factor of poor prognosis for MACCE (odds ratio, 1.84; 95% confidence interval, 1.01-3.36; p= 0.045).Conclusion: Glycemic variability determined with a CGMS is a predictor of prognosis in patients with ACS without severe DM.

DOI： 10.1186/s12933-018-0761-5

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Hyperinsulinemia/Insulin-Resistance Causes Left Ventricular Remodeling in Patients With a First STEMI Despite the Smaller Infarction: 3D Speckle Tracking Study

Noriaki Iwahashi, Hironori Takahashi, Yuichiro Kimura, Yasushi Matsuzawa, Masaaki Konishi, Nobuhiko Maejima, Kiyoshi Hibi, Masami Kosuge, Toshiaki Ebina, Kazuo Kimura, Kouichi Tamura

CIRCULATION 136 2017.11

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Long-term outcomes and operators' experience in primary percutaneous coronary intervention for ST-segment elevation myocardial infarction.

Kei Takamizawa, Masaomi Gohbara, Yohei Hanajima, Katsuhiko Tsutsumi, Hidekuni Kirigaya, Jin Kirigaya, Hidefumi Nakahashi, Yugo Minamimoto, Yuichiro Kimura, Noriyuki Kawaura, Kensuke Matsushita, Kozo Okada, Masaaki Konishi, Noriaki Iwahashi, Masami Kosuge, Teruyasu Sugano, Toshiaki Ebina, Kiyoshi Hibi

Cardiovascular intervention and therapeutics 40 ( 1 ) 57 - 67 2025.1

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Primary percutaneous coronary intervention (pPCI) for ST-segment elevation myocardial infarction (STEMI) is typically performed by experienced operators. Therefore, the safety of pPCI for STEMI performed by less experienced operators with the support of experienced operators remains unknown. We aimed to investigate the long-term outcomes of pPCI for STEMI performed by less experienced operators with the support of experienced operators. In total, 775 STEMI patients were enrolled and divided into groups according to operator experience in PCI: less experienced (n = 384) and experienced (n = 391) operator groups. Experienced operators were defined as those who had performed > 50 elective PCI procedures per year as the first operator or instructional assistant, whereas less experienced operators were defined as others. When less experienced operators performed the pPCI, experienced operators supported them. The primary endpoint was any cardiovascular event, defined as a composite of cardiovascular death, nonfatal myocardial infarction, and unplanned hospitalization for heart failure. In the propensity score-matched analysis, 324 patients were included in each group. The cumulative incidence of the primary endpoint over a median of 5 years in the less experienced operator group was similar to that in the experienced operator group (15% vs. 18%, P = 0.209). In the multivariate Cox proportional hazards model, there was no excess risk for patients operated upon by less experienced operators for the primary endpoint (adjusted hazard ratio, 0.85; 95% confidence interval, 0.58-1.25; P = 0.417). pPCI for STEMI by less experienced operators did not increase the risk of in-hospital mortality or 5-year long-term cardiovascular events if supported by experienced operators.

DOI： 10.1007/s12928-024-01059-5

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Effect of balloon pulmonary angioplasty on chronic thromboembolic pulmonary hypertension: an assessment of the learning curve in a Japanese university hospital

Naohiro Komura, Teruyasu Sugano, Fumiaki Ono, Mina Nakayama, Toru Suzuki, Noriyuki Kawaura, Junya Hosoda, Masaaki Konishi, Noriaki Iwahashi, Tomoaki Ishigami, Makoto Mo, Kiyoshi Hibi

Cardiovascular Intervention and Therapeutics 2025

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Balloon pulmonary angioplasty (BPA) is an innovative treatment for chronic thromboembolic pulmonary hypertension (CTEPH). We retrospectively examined the clinical outcomes and complications of BPA at Yokohama City University Hospital (YCUH) between 2012 and 2018. In 2012, we began to conduct BPA sessions in 46 patients with inoperable CTEPH; 34 completed the BPA scheme and the follow-up plan. A longitudinal sub-analysis was performed with cohorts 1 and 2 receiving BPA before and after April 2015. Significant improvements in the mean pulmonary arterial pressure, pulmonary vascular resistance, and other parameters were detected after BPA. The total rate of thoracic complications was 25%. Specifically, the increase in SaO2 and home oxygen therapy discontinuation rate, and oral riociguat discontinuation rate was significantly higher in cohort 2 (+ 7.7, 75, and 59%) compared to cohort 1 (+ 3.1, 27, and 10%) (P < 0.05). Moreover, the need for non-invasive positive pressure ventilation was significantly lower: 0% (cohort 2) vs. 7% (cohort 1) (P < 0.05). The BPA sessions conducted at the YCUH resulted in significant improvements in patients with CTEPH. This study demonstrates a clear learning curve regarding the effectiveness of BPA both in normalizing SaO2 and facilitating the cessation of home oxygen therapy, as well as in reducing the incidence of severe complications.

DOI： 10.1007/s12928-024-01076-4

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Effect of balloon pulmonary angioplasty on chronic thromboembolic pulmonary hypertension: an assessment of the learning curve in a Japanese university hospital.

Naohiro Komura, Teruyasu Sugano, Fumiaki Ono, Mina Nakayama, Toru Suzuki, Noriyuki Kawaura, Junya Hosoda, Masaaki Konishi, Noriaki Iwahashi, Tomoaki Ishigami, Makoto Mo, Kiyoshi Hibi

Cardiovascular intervention and therapeutics 2024.12

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Balloon pulmonary angioplasty (BPA) is an innovative treatment for chronic thromboembolic pulmonary hypertension (CTEPH). We retrospectively examined the clinical outcomes and complications of BPA at Yokohama City University Hospital (YCUH) between 2012 and 2018. In 2012, we began to conduct BPA sessions in 46 patients with inoperable CTEPH; 34 completed the BPA scheme and the follow-up plan. A longitudinal sub-analysis was performed with cohorts 1 and 2 receiving BPA before and after April 2015. Significant improvements in the mean pulmonary arterial pressure, pulmonary vascular resistance, and other parameters were detected after BPA. The total rate of thoracic complications was 25%. Specifically, the increase in SaO2 and home oxygen therapy discontinuation rate, and oral riociguat discontinuation rate was significantly higher in cohort 2 (+ 7.7, 75, and 59%) compared to cohort 1 (+ 3.1, 27, and 10%) (P < 0.05). Moreover, the need for non-invasive positive pressure ventilation was significantly lower: 0% (cohort 2) vs. 7% (cohort 1) (P < 0.05). The BPA sessions conducted at the YCUH resulted in significant improvements in patients with CTEPH. This study demonstrates a clear learning curve regarding the effectiveness of BPA both in normalizing SaO2 and facilitating the cessation of home oxygen therapy, as well as in reducing the incidence of severe complications.

DOI： 10.1007/s12928-024-01076-4

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High Detectability of Prehospital 12-Lead Electrocardiogram in Diagnosing Spasm-Induced Acute Coronary Syndrome.

Jin Kirigaya, Yasushi Matsuzawa, Masami Kosuge, Takeru Abe, Noriaki Iwahashi, Kengo Terasaka, Hisaya Kondo, Kensuke Matsushita, Masaomi Gohbara, Kozo Okada, Masaaki Konishi, Toshiaki Ebina, Teruyasu Sugano, Kiyoshi Hibi

Circulation journal : official journal of the Japanese Circulation Society 2024.9

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BACKGROUND: The importance of prehospital (PH) electrocardiograms (ECG) recorded by emergency medical services (EMS) for diagnosing coronary artery spasm-induced acute coronary syndrome (CS-ACS) remains unclear. METHODS AND RESULTS: We enrolled 340 consecutive patients with ACS who were transported by EMS within 12 h of symptom onset. According to Japanese Circulation Society guidelines, CS-ACS (n=48) was diagnosed with or without a pharmacological provocation test (n=34 and n=14, respectively). Obstructive coronary artery-induced ACS (OC-ACS; n=292) was defined as ACS with a culprit lesion showing 99% stenosis or >75% stenosis with plaque rupture or thrombosis observed via angiographic and intravascular imaging. Ischemic ECG findings included ST-segment deviation (elevation or depression) and negative T and U waves. In CS-ACS, the prevalence of ST-segment deviation decreased significantly from PH-ECG to emergency room (ER) ECG (77.0% vs. 35.4%; P<0.001), as did the prevalence of overall ECG abnormalities (81.2% vs. 45.8%; P<0.001). Conversely, in OC-ACS, there was a similar prevalence on PH-ECG and ER-ECG of ST-segment deviations (94.8% vs. 92.8%, respectively; P=0.057) and abnormal ECG findings (96.9% vs. 95.2%, respectively; P=0.058). Patients with abnormal PH-ECG findings that disappeared upon arrival at hospital without ER-ECG or troponin abnormalities were more frequent in the CS-ACS than OC-ACS group (20.8% vs. 1.0%; P<0.001). CONCLUSIONS: PH-ECG is valuable for detecting abnormal ECG findings that disappear upon arrival at hospital in CS-ACS patients.

DOI： 10.1253/circj.CJ-24-0485

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Benefit of prehospital electrocardiogram on door-to-device time in ST-segment elevation myocardial infarction with cardiogenic shock: Data from the Kanagawa Acute Cardiovascular Registry. International journal

Jin Kirigaya, Yasushi Matsuzawa, Toshiaki Ebina, Takeru Abe, Noriaki Iwahashi, Kazuki Fukui, Atsuo Maeda, Yoshihiro Akashi, Junya Ako, Yuji Ikari, Atsuo Namiki, Ichiro Michishita, Teruyasu Sugano, Kouichi Tamura, Kiyoshi Hibi, Kazuo Kimura, Hiroshi Suzuki

Journal of cardiology 2024.8

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BACKGROUND: The benefit of prehospital 12‑lead electrocardiogram (PH-ECG) performed by emergency medical service personnel at the site of first medical contact (FMC) in patients with ST-segment elevation myocardial infarction (STEMI) with cardiogenic shock (CS-STEMI) remains unclear. This study aimed to investigate the effect of PH-ECG on door-to-device time in patients with CS-STEMI. METHODS: This study enrolled CS-STEMI (Killip class IV) patients who were transferred directly to hospitals by ambulance (n = 517) from the Kanagawa Acute Cardiovascular Registry database. Patients were divided into PH-ECG (+) (n = 270) and PH-ECG (-) (n = 247) groups. Patients who experienced out-of-hospital cardiac arrest, who did not undergo emergent coronary intervention, or whose data were missing were excluded. Patient characteristics, FMC-to-door time, door-to-device time, and in-hospital mortality were compared between the groups. RESULTS: The patient backgrounds of the PH-ECG (+) and PH-ECG (-) groups were comparable. The peak creatinine kinase level was greater in the PH-ECG (+) group than in the PH-ECG (-) group [2756 (1292-6009) IU/ml vs. 2270 (957-5258) IU/ml, p = 0.048]. The FMC-to-door time was similar between the two groups [25 (20-33) min vs. 27 (20-35) min, p = 0.530], while the door-to-device time was significantly shorter in the PH-ECG group [74 (52-103) min vs. 83 (62-111) min, p = 0.007]. In-hospital mortality did not differ between the two groups (18 % vs. 21 %, p = 0.405). Multivariable logistic regression analyses revealed that PH-ECG (+) was independently associated with a door-to-device time < 60 min [odds ratio (95 % confidence intervals): 1.88 (1.24-2.83), p = 0.003]. CONCLUSIONS: PH-ECG was significantly associated with shorter door-to-device times in patients with CS-STEMI. Further studies with larger populations and more defined protocols are required to evaluate the utility of PH-ECG in patients with CS-STEMI.

DOI： 10.1016/j.jjcc.2024.08.004

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腫瘍関連腫瘍循環器としての肺高血圧症の検討

鈴木徹, 岩橋徳明, 相澤広太郎, 峯岸慎太郎, 小村直弘, 川浦範之, 小西正紹, 石上友章, 菅野晃靖, 日比潔

日本肺高血圧・肺循環学会学術集会抄録集 9回 124 - 124 2024.8

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バルーン肺動脈形成術(BPA)施行も救命できなかったAcute on chronic PTEによる心肺停止の一例

小村直弘, 菅野晃靖, 鈴木徹, 川浦範之, 小西正紹, 岩橋徳明, 日比潔

日本心血管インターベンション治療学会抄録集 32回 MO41 - 5 2024.7

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Impact of New-Onset Right Bundle-Branch Block After Transcatheter Aortic Valve Replacement on Permanent Pacemaker Implantation. International journal

Shinnosuke Kikuchi, Yugo Minamimoto, Kensuke Matsushita, Tomoki Cho, Kengo Terasaka, Yohei Hanajima, Hidefumi Nakahashi, Masaomi Gohbara, Yuichiro Kimura, Shota Yasuda, Kozo Okada, Yasushi Matsuzawa, Noriaki Iwahashi, Masami Kosuge, Toshiaki Ebina, Olivier Morel, Patrick Ohlmann, Keiji Uchida, Kiyoshi Hibi

Journal of the American Heart Association 13 ( 9 ) e032777 2024.5

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BACKGROUND: A delayed and recurrent complete atrioventricular block (CAVB) is a life-threatening complication of transcatheter aortic valve replacement (TAVR). Post-TAVR evaluation may be important in predicting delayed and recurrent CAVB requiring permanent pacemaker implantation (PPI). The impact of new-onset right bundle-branch block (RBBB) after TAVR on PPI remains unknown. METHODS AND RESULTS: In total, 407 patients with aortic stenosis who underwent TAVR were included in this analysis. Intraprocedural CAVB was defined as CAVB that occurred during TAVR. A 12-lead ECG was evaluated at baseline, immediately after TAVR, on postoperative days 1 and 5, and according to the need to identify new-onset bundle-branch block (BBB) and CAVB after TAVR. Forty patients (9.8%) required PPI, 17 patients (4.2%) had persistent intraprocedural CAVB, and 23 (5.7%) had delayed or recurrent CAVB after TAVR. The rates of no new-onset BBB, new-onset left BBB, and new-onset RBBB were 65.1%, 26.8%, and 4.7%, respectively. Compared with patients without new-onset BBB and those with new-onset left BBB, the rate of PPI was higher in patients with new-onset RBBB (3.4% versus 5.6% versus 44.4%, P<0.0001). On post-TAVR evaluation in patients without persistent intraprocedural CAVB, the multivariate logistic regression analysis showed that new-onset RBBB was a statistically significant predictor of PPI compared with no new-onset BBB (odds ratio [OR], 18.0 [95% CI, 5.94-54.4]) in addition to the use of a self-expanding valve (OR, 2.97 [95% CI, 1.09-8.10]). CONCLUSIONS: Patients with new-onset RBBB after TAVR are at high risk for PPI.

DOI： 10.1161/JAHA.123.032777

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Association between evolocumab use and slow progression of aortic valve stenosis.

Kengo Terasaka, Masaomi Gohbara, Takeru Abe, Tomohiro Yoshii, Yohei Hanajima, Jin Kirigaya, Mutsuo Horii, Shinnosuke Kikuchi, Hidefumi Nakahashi, Kensuke Matsushita, Yugo Minamimoto, Kozo Okada, Yasushi Matsuzawa, Noriaki Iwahashi, Masami Kosuge, Teruyasu Sugano, Toshiaki Ebina, Kiyoshi Hibi

Heart and vessels 2024.3

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No medications have been reported to inhibit the progression of aortic valve stenosis (AS). The present study aimed to investigate whether evolocumab use is related to the slow progression of AS evaluated by serial echocardiography. This was a retrospective observational study from 2017 to 2022 at Yokohama City University Medical Center. Patients aged ≥ 18 with moderate AS were included. Exclusion criteria were (1) mild AS; (2) severe AS defined by maximum aortic valve (AV) velocity ≥ 4.0 m/s; and/or (3) no data of annual follow-up echocardiography. The primary endpoint was the association between evolocumab use and annual changes in the maximum AV-velocity or peak AV-pressure gradient (PG). A total of 57 patients were enrolled: 9 patients treated with evolocumab (evolocumab group), and the other 48 patients assigned to a control group. During a median follow-up of 33 months, the cumulative incidence of AS events (a composite of all-cause death, AV intervention, or unplanned hospitalization for heart failure) was 11% in the evolocumab group and 58% in the control group (P = 0.012). Annual change of maximum AV-velocity or peak AV-PG from the baseline to the next year was 0.02 (- 0.18 to 0.22) m/s per year or 0.60 (- 4.20 to 6.44) mmHg per year in the evolocumab group, whereas it was 0.29 (0.04-0.59) m/s per year or 7.61 (1.46-16.48) mmHg per year in the control group (both P < 0.05). Evolocumab use was associated with slow progression of AS and a low incidence of AS events in patients with moderate AS.

DOI： 10.1007/s00380-024-02386-6

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Elevated Leukocyte Count and Platelet-Derived Thrombogenicity Measured Using the Total Thrombus-Formation Analysis System in Patients with ST-Segment Elevation Myocardial Infarction.

Shinnosuke Kikuchi, Kengo Tsukahara, Shinya Ichikawa, Takeru Abe, Hidefumi Nakahashi, Yugo Minamimoto, Yuichiro Kimura, Eiichi Akiyama, Kozo Okada, Yasushi Matsuzawa, Masaaki Konishi, Nobuhiko Maejima, Noriaki Iwahashi, Masami Kosuge, Toshiaki Ebina, Kouichi Tamura, Kazuo Kimura, Kiyoshi Hibi

Journal of atherosclerosis and thrombosis 2024.3

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AIMS: High platelet-derived thrombogenicity during the acute phase of ST-segment elevation myocardial infarction (STEMI) is associated with poor outcomes; however, the associated factors remain unclear. This study aimed to examine whether acute inflammatory response after STEMI affects platelet-derived thrombogenicity. METHODS: This retrospective observational single-center study included 150 patients with STEMI who were assessed for platelet-derived thrombogenicity during the acute phase. Platelet-derived thrombogenicity was assessed using the area under the flow-pressure curve for platelet chip (PL-AUC), which was measured using the total thrombus-formation analysis system (T-TAS). The peak leukocyte count was evaluated as an acute inflammatory response after STEMI. The patients were divided into two groups: the highest quartile of the peak leukocyte count and the other three quartiles combined. RESULTS: Patients with a high peak leukocyte count (＞15,222/mm3; n=37) had a higher PL-AUC upon admission (420 [386-457] vs. 385 [292-428], p=0.0018), higher PL-AUC during primary percutaneous coronary intervention (PPCI) (155 [76-229] vs. 96 [29-170], p=0.0065), a higher peak creatine kinase level (4200±2486 vs. 2373±1997, p＜0.0001), and higher PL-AUC 2 weeks after STEMI (119 [61-197] vs. 88 [46-122], p=0.048) than those with a low peak leukocyte count (≤ 15,222/mm3; n=113). The peak leukocyte count after STEMI positively correlated with PL-AUC during primary PPCI (r=0.37, p＜0.0001). A multivariable regression analysis showed the peak leukocyte count to be an independent factor for PL-AUC during PPCI (β=0.26, p=0.0065). CONCLUSIONS: An elevated leukocyte count is associated with high T-TAS-based platelet-derived thrombogenicity during the acute phase of STEMI.

DOI： 10.5551/jat.64395

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Legs Elevation Method may be Useful for Diagnosis of Exclusion for Exercised Pulmonary Hypertension(タイトル和訳中)

鈴木徹, 相澤広太郎, 峯岸慎太郎, 小村直弘, 川浦範之, 小西正紹, 岩橋徳明, 石上友章, 菅野晃靖, 日比潔

日本循環器学会学術集会抄録集 88回 PJ062 - 3 2024.3

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Ratio of left ventricular outflow tract area to aortic annulus area and complete atrioventricular block after transcatheter aortic valve replacement for aortic stenosis. International journal

Shinnosuke Kikuchi, Yugo Minamimoto, Kensuke Matsushita, Tomoki Cho, Kengo Terasaka, Yohei Hanajima, Hidefumi Nakahashi, Masaomi Gohbara, Yuichiro Kimura, Shota Yasuda, Kozo Okada, Yasushi Matsuzawa, Noriaki Iwahashi, Masami Kosuge, Toshiaki Ebina, Olivier Morel, Patrick Ohlmann, Keiji Uchida, Kiyoshi Hibi

International journal of cardiology 397 131608 - 131608 2024.2

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BACKGROUND: Mechanical compression of cardiac conduction system by transcatheter heart valves leads to complete atrioventricular block (CAVB) after transcatheter aortic valve replacement (TAVR). Bulging of ventricular septum in the left ventricular outflow tract (LVOT) may be associated with greater compression of conduction system, leading to irreversible CAVB. OBJECTIVE: This study aimed to investigate the association of ventricular septal bulging with TAVR-related CAVB and permanent pacemaker implantation (PPI). METHODS: Among 294 consecutive patients with severe aortic stenosis who underwent TAVR between July 2017 and February 2023, 271 were included in the analysis. As a quantitative evaluation of bulging of the ventricular septum, the ratio of LVOT area to aortic annulus area (L/A ratio) was measured at the systolic phase of computed tomography images. RESULTS: TAVR-related CAVB occurred in 64 patients (23.6%). Twenty-eight patients (10.3%) required PPI. The optimal thresholds of L/A ratio for predicting TAVR-related CAVB and PPI were 1.0181 and 0.985, respectively. Patients with less than the cut-off values had higher rate of TAVR-related CAVB and PPI than those above (28.3% vs 13.1%, p = 0.0063; 14.7% vs 4.4%, p = 0.0077, respectively). A multivariate analysis showed that L/A ratio < 1.0181 was an independent predictor of TAVR-related CAVB (odds ratio [OR] 2.65, p = 0.011), in addition to prior right bundle branch block (OR 3.76, p = 0.0005), use of a self-expanding valve (OR 1.99, p = 0.030), and short membranous septum length (OR 0.96, p = 0.037). Only L/A ratio < 0.985 was independently associated with PPI (OR 3.70, p = 0.011). CONCLUSION: Low L/A ratio is a predictor of TAVR-related CAVB and PPI.

DOI： 10.1016/j.ijcard.2023.131608

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Influence of Obstructive Apnea Index on Persistent Left Ventricular Dysfunction in Patients with ST-Segment Elevation Myocardial Infarction. International journal

Jin Kirigaya, Noriaki Iwahashi, Tomoaki Ishigami, Takeru Abe, Masaomi Gohbara, Yohei Hanajima, Mutsuo Horii, Kozo Okada, Yasushi Matsuzawa, Masami Kosuge, Toshiaki Ebina, Kiyoshi Hibi

Journal of clinical medicine 13 ( 4 ) 2024.2

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Background: We retrospectively investigated the effects of the severity and classification of sleep-disordered breathing (SDB) on left ventricular (LV) function in patients with ST-segment elevation myocardial infarction (STEMI). Methods: A total of 115 patients with STEMIs underwent a sleep study using a multichannel frontopolar electroencephalography recording device (Sleep Profiler) one week after STEMI onset. We evaluated LV global longitudinal strain (LV-GLS) using two-dimensional echocardiography at one week and seven months. Patients were classified as no SDB (AHI < 5 events/h), obstructive SDB (over 50% of apnea events are obstructive), and central SDB (over 50% of apnea events are central). Due to the device's limitations in distinguishing obstructive from central hypopnea, SDB classification was based on apnea index percentages. Results: The obstructive apnea index (OAI) was significantly associated with LV-GLS at one week (r = 0.24, p = 0.027) and seven months (r = 0.21, p = 0.020). No such correlations were found for the central apnea index and SDB classification. Multivariable regression analysis showed that the OAI was independently associated with LV-GLS at one week (β = 0.24, p = 0.002) and seven months (β = 0.20, p = 0.008). Conclusions: OAI is associated with persistent LV dysfunction assessed by LV-GLS in STEMI.

DOI： 10.3390/jcm13040986

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Coronary protection using a pressure wire during transcatheter aortic valve implantation.

Shinnosuke Kikuchi, Kengo Terasaka, Yugo Minamimoto, Tomoki Cho, Kozo Okada, Yasushi Matsuzawa, Noriaki Iwahashi, Keiji Uchida, Kiyoshi Hibi

Journal of cardiology cases 29 ( 2 ) 73 - 77 2024.2

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UNLABELLED: Coronary obstruction is a rare but life-threatening complication of transcatheter aortic valve implantation (TAVI). This article describes the case of a patient with severe aortic valve stenosis treated with TAVI, during which preventive coronary wiring using a pressure wire was performed for coronary protection. After the deployment of the transcatheter heart valve (THV), the values of the fractional flow reserve (FFR) and resting full-cycle ratio (RFR) remarkably decreased, although the findings of transesophageal echocardiography and coronary angiography did not suggest coronary obstruction. Intravascular ultrasound revealed severe stenosis in the left main trunk due to the displacement of the calcified native leaflets. The decrease in the FFR and RFR values after THV deployment led to a diagnosis of partial coronary obstruction, and percutaneous coronary intervention was successfully performed. In patients at a high risk for coronary obstruction, coronary protection with a pressure wire is useful for the diagnosis and prevention of coronary flow deterioration during TAVI. Functional assessment using a pressure wire before and after TAVI may contribute to the accurate diagnosis of coronary obstruction. LEARNING OBJECTIVE: Accurate diagnosis of coronary obstruction during transcatheter aortic valve implantation (TAVI) is important for successful management. In patients at a high risk for coronary obstruction, coronary protection with a pressure wire is useful for the diagnosis and prevention of coronary flow deterioration during TAVI. The remarkable decrease in the fractional flow reserve and resting full-cycle ratio values after the deployment of the transcatheter heart valve may suggest coronary obstruction.

DOI： 10.1016/j.jccase.2023.10.008

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Clinical Usefulness of Echocardiographic Measurement of Proximal Aortic Diameter in Early Differentiation Between Type A Acute Aortic Dissection and ST-Segment-Elevation Myocardial Infarction. International journal

Jin Kirigaya, Noriaki Iwahashi, Takeru Abe, Masaomi Gohbara, Yohei Hanajima, Mutsuo Horii, Kozo Okada, Yasushi Matsuzawa, Shota Yasuda, Masami Kosuge, Toshiaki Ebina, Ichiro Takeuchi, Keiji Uchida, Kouichi Tamura, Kiyoshi Hibi

Journal of the American Heart Association e029506 2023.10

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Background Contradictions between management modalities of type A acute aortic dissection (TAAAD) and ST-elevation-myocardial infarction (STEMI) may result in clinical catastrophe. Therefore, we aimed to explore which 2-dimensional echocardiography (2DE) findings are optimal for differentiating TAAAD from STEMI. Methods and Results This study included 340 patients with STEMI and 340 patients with TAAAD who underwent 2DE in the emergency department between 2012 and 2021. The proximal ascending aorta (PAA) diameter and other echocardiographic parameters were analyzed. PAA diameters were measured at 4 levels in the parasternal view: Valsalva, the sinotubular junction (STJ), the PAA at 1 cm above the STJ, and the PAA at 2 cm above the STJ. Receiver-operating characteristic curve analysis showed that Valsalva, STJ, PAA at 1 cm above the STJ, and PAA at 2 cm above the STJ were significant predictors of TAAAD (areas under the curve: 0.777, 0.924, 0.965, and 0.975, respectively; P<0.001) with the respective cutoff values of 39.4, 38.5, 39.8, and 41.2 mm. Multivariable analysis suggested that all 2DE parameters were significant predictors of TAAAD. Among the 2DE parameters examined, the incorporation of PAA at 2 cm above the STJ to clinical indicators exhibited the most significant diagnostic capability (C-statistics, 0.97; net reclassification improvement, 1.81; integrated discrimination improvement, 0.61). When only TAAAD with coronary malperfusion and STEMI were analyzed, the diagnostic utility of PAA at 1 cm above the STJ was evident (C-statistics, 0.99; net reclassification improvement, 1.79; integrated discrimination improvement, 0.67), with PAA at 2 cm above the STJ ranking second in diagnostic significance (C-statistics, 0.99; net reclassification improvement, 1.12; integrated discrimination improvement, 0.66). Conclusions PAA measurements were the most beneficial for diagnosing TAAAD in all 2DE findings and TAAAD from STEMI.

DOI： 10.1161/JAHA.123.029506

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Impact of Low-Density Lipoprotein Cholesterol Levels at Acute Coronary Syndrome Admission on Long-Term Clinical Outcomes.

Ryosuke Sato, Yasushi Matsuzawa, Tomohiro Yoshii, Eiichi Akiyama, Masaaki Konishi, Hidefumi Nakahashi, Yugo Minamimoto, Yuichiro Kimura, Kozo Okada, Nobuhiko Maejima, Noriaki Iwahashi, Masami Kosuge, Toshiaki Ebina, Kazuo Kimura, Kouichi Tamura, Kiyoshi Hibi

Journal of atherosclerosis and thrombosis 2023.10

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AIM: Low-density lipoprotein cholesterol (LDL-C) level reduction is highly effective in preventing the occurrence of a cardiovascular event. Contrariwise, an inverse association exists between LDL-C levels and prognosis in some patients with cardiovascular diseases-the so-called "cholesterol paradox." This study aimed to investigate whether the LDL-C level on admission affects the long-term prognosis in patients who develop acute coronary syndrome (ACS) and to examine factors associated with poor prognosis in patients with low LDL-C levels. METHODS: We enrolled 410 statin-naïve patients with ACS, whom we divided into low- and high-LDL-C groups based on an admission LDL-C cut-off (obtained from the Youden index) of 122 mg/dL. Endothelial function was assessed using the reactive hyperemia index 1 week after statin initiation. The primary composite endpoint included all-cause death, as well as myocardial infarction and ischemic stroke occurrences. RESULTS: During a median follow-up period of 6.1 years, 76 patients experienced the primary endpoint. Multivariate Cox regression analysis revealed that patients in the low LDL-C group had a 2.3-fold higher risk of experiencing the primary endpoint than those in the high LDL-C group (hazard ratio, 2.34; 95% confidence interval, 1.29-4.27; p=0.005). In the low LDL-C group, slow gait speed (frailty), elevated chronic-phase high-sensitivity C-reactive protein levels (chronic inflammation), and endothelial dysfunction were significantly associated with the primary endpoint. CONCLUSIONS: Patients with low LDL-C levels at admission due to ACS had a significantly worse long-term prognosis than those with high LDL-C levels; frailty, chronic inflammation, and endothelial dysfunction were poor prognostic factors.

DOI： 10.5551/jat.64368

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先天性横隔膜ヘルニア術後の若年女性に発症した肺高血圧症の1例

相澤広太郎, 日比潔, 石上友章, 岩橋徳明, 小西正昭, 細田順也, 川浦範之, 小村直弘, 峯岸慎太郎, 鈴木徹

日本内科学会関東地方会 689回 30 - 30 2023.9

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先天性横隔膜ヘルニア術後の若年女性に発症した肺高血圧症の1例

相澤広太郎, 日比潔, 石上友章, 岩橋徳明, 小西正昭, 細田順也, 川浦範之, 小村直弘, 峯岸慎太郎, 鈴木徹

日本内科学会関東地方会 689回 30 - 30 2023.9

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肺高血圧診断基準変更の意義肺高血圧症の新基準は早期薬物介入の可能性を高める

岩橋徳明, 小村直弘, 鈴木徹, 川浦範之, 堀井睦夫, 菅野晃靖, 石上友章, 田村功一, 日比潔

日本心臓病学会学術集会抄録 71回 S6 - 6 2023.9

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STEMIのprimary PCIにおける若年術者と上級術者の長期予後比較

郷原正臣, 桐ヶ谷仁, 桐ヶ谷英邦, 菊地進之介, 中橋秀文, 南本祐吾, 岩田究, 小村直弘, 岡田興造, 松澤泰志, 小西正紹, 川浦範之, 岩橋徳明, 菅野晃靖, 海老名俊明, 日比潔

日本心血管インターベンション治療学会抄録集 31回 MP57 - 1 2023.8

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Echocardiographic Findings of Malignant Lymphoma with Cardiac Involvement: A Single-center Retrospective Observational Study.

Toshiaki Ebina, Yuka Sano, Michiko Hirabayashi, Tomomi Tsurumi, Mika Watanabe, Mio Furukawa, Wakana Matsuo, Hazuki Nagasawa, Haruka Hirose, Mutsuo Horii, Yuki Nakajima, Shin Fujisawa, Noriaki Iwahashi, Kiyoshi Hibi

Internal medicine (Tokyo, Japan) 2023.5

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Objectives Although malignant lymphoma (ML) can occur in every organ, diagnosing cardiac involvement without cardiac manifestations is difficult. We therefore investigated the incidence of cardiac involvement in ML in our hospital and clarified the transthoracic echocardiography (TTE) findings of cardiac involvement. Methods Patients with ML referred to our hospital between January 2013 and December 2019 were retrospectively reviewed. Patients During the study period, 453 patients were identified. The mean age was 64.9 years old, and 54% of the patients were men. Results Diffuse large B-cell lymphoma (DLBCL) was the most common lymphoma, followed by follicular lymphoma. Of the 453 patients, 394 (87.0%) underwent TTE at the initial diagnosis or during the clinical course. The performance rates of TTE in DLBCL, Hodgkin lymphoma, and mantle cell lymphoma were above 90%. Cardiac involvement was detected in 6 (five with DLBCL and one with B-cell lymphoma) (1.5%) of the 394 patients who underwent TTE. The involved lesions of the heart varied, and five patients had pericardial effusion. Five patients had a preserved left ventricular ejection fraction. All patients were treated with chemotherapy, and some were treated with radiation and surgery. Conclusion Cardiac involvement was observed in six (1.5%) of the patients with ML who underwent TTE. B-cell lymphoma, especially DLBCL, is a common ML with cardiac involvement. Although five patients had pericardial effusion, the involved lesions of the heart were not uniform. TTE is a useful imaging modality to noninvasively and repeatedly evaluate the tumor characteristics, response to ML treatment, and cardiac function.

DOI： 10.2169/internalmedicine.1902-23

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Endothelial dysfunction predicts bleeding and cardiovascular death in acute coronary syndrome. International journal

Tomohiro Yoshii, Yasushi Matsuzawa, So Kato, Ryosuke Sato, Youhei Hanajima, Shinnosuke Kikuchi, Hidefumi Nakahashi, Masaaki Konishi, Eiichi Akiyama, Yugo Minamimoto, Yuichiro Kimura, Kozo Okada, Nobuhiko Maejima, Noriaki Iwahashi, Toshiaki Ebina, Kiyoshi Hibi, Masami Kosuge, Toshihiro Misumi, Kouichi Tamura, Kazuo Kimura

International journal of cardiology 376 11 - 17 2023.4

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BACKGROUNDS: Recently, there has been increasing awareness that bleeding may lead to adverse outcomes. Endothelial dysfunction is associated with increased risk of cardiovascular and bleeding events. This study aimed to investigate the association of endothelial dysfunction with major bleeding and specific causes of death in addition to major adverse cardiovascular events in patients with acute coronary syndrome. METHODS: This single-centre retrospective observational study was conducted at a tertiary-care hospital; patients with acute coronary syndrome were included between June 2010 and November 2014 (median follow-up, 6.1 years). The reactive hyperaemia index was assessed before their discharge; reactive hyperaemia index <1.67 was defined as endothelial dysfunction. The main outcomes were the incidence of major bleeding, all-cause death, cardiovascular death, non-cardiovascular death, resuscitated cardiac arrest, non-fatal myocardial infarction, non-fatal stroke, and hospitalisation for heart failure. RESULTS: Among the included 674 patients with acute coronary syndrome, 264 (39.2%) had endothelial dysfunction. Multivariable Cox-hazard analyses revealed an independent predictive value of endothelial dysfunction for major bleeding (hazard ratio 2.29, 95% confidence interval 1.17-4.48, P = 0.016) and major adverse cardiovascular events (hazard ratio 2.04, 95% confidence interval 1.43-2.89, P < 0.001). The endothelial dysfunction group patients had a 2.5-fold greater risk of cardiovascular death; however, no association was found with non-cardiovascular death. CONCLUSION: Endothelial dysfunction assessed using reactive hyperaemia index predicted future major cardiovascular event as well as major bleeding and cardiovascular death in patients with acute coronary syndrome.

DOI： 10.1016/j.ijcard.2023.01.079

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Relationship between Microbiota-derived Trimethylamine N-oxide Levels and Long-term Prognosis after Guideline-based Secondary Prevention Therapy in Patients with Acute Myocardial Infarction(タイトル和訳中)

中橋秀文, 松澤泰志, 岩橋徳明, 岡田興造, 木村裕一郎, 南本祐吾, 郷原正臣, 菊地進之介, 小菅雅美, 木村一雄, 田村功一, 日比潔

日本循環器学会学術集会抄録集 87回 OJ02 - 2 2023.3

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Clinical impact of left ventricular systolic dysfunction in patients undergoing dialysis access surgery

Sanae Saka, Masaaki Konishi, Daisuke Kamimura, Hiromichi Wakui, Yasushi Matsuzawa, Kozo Okada, Jin Kirigaya, Noriaki Iwahashi, Teruyasu Sugano, Tomoaki Ishigami, Nobuhito Hirawa, Kiyoshi Hibi, Toshiaki Ebina, Kazuo Kimura, Kouichi Tamura

Clinical and Experimental Nephrology 2023.2

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Publishing type：Research paper (scientific journal) Publisher：Springer Science and Business Media LLC

DOI： 10.1007/s10157-023-02323-3

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Other Link： https://link.springer.com/article/10.1007/s10157-023-02323-3/fulltext.html
Culprit Lesion Morphology of Rapidly Progressive and Extensive Anterior-Wall ST-Segment Elevation Myocardial Infarction

Kozo Okada, Kiyoshi Hibi, Shinnosuke Kikuchi, Hidekuni Kirigaya, Yohei Hanajima, Ryosuke Sato, Hidefumi Nakahashi, Yugo Minamimoto, Yasushi Matsuzawa, Nobuhiko Maejima, Noriaki Iwahashi, Masami Kosuge, Toshiaki Ebina, Kouichi Tamura, Kazuo Kimura

Circulation: Cardiovascular Imaging 15 ( 11 ) 2022.11

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Publishing type：Research paper (scientific journal) Publisher：Ovid Technologies (Wolters Kluwer Health)

Background:

Rapidly progressive, extensive myocardial injury/infarction (RPEMI) beyond the concept of wave-front phenomenon can be observed even when achieving timely reperfusion; however, the pathogenesis of RPEMI remains unknown. This retrospective study investigated clinical and lesion characteristics of RPEMI, focusing on culprit-lesion morphology (CLM).

Methods:

Among patients with extensive anterior-wall ST-segment elevation myocardial infarction due to proximal left anterior descending artery lesions who had reperfusion within 3 hours of symptom onset, 60 patients undergoing both intravascular ultrasound and cardiac magnetic resonance imaging were enrolled. Myocardial injury/infarction before reperfusion therapy was assessed by QRS scores at hospitalization electrocardiogram, and the extent of myocardial injury/infarction was evaluated by cardiac magnetic resonance imaging, which measured area at risk, infarct size, myocardial salvage index, microvascular obstruction, and left ventricular ejection fraction. RPEMI was defined as lower left ventricular ejection fraction (less median value) with microvascular obstruction.

Results:

Despite comparable onset-to-door and onset-to-reperfusion times and area at risk, patients with RPEMI showed higher QRS scores at hospitalization (5 [4.3–6] versus 3 [2–4], P <0.001) and infarct size (26.5±9.1 versus 20.4±10.5%, P =0.04), and a tendency toward lower myocardial salvage index (0.27±0.14 versus 0.36±0.20, P =0.10) compared with those without. Patients with versus without RPEMI more frequently observed specific CLM on intravascular ultrasound, characterized by the combination of vulnerable plaques, plaque ruptures, and/or large thrombi. When stratified by CLM-score composed of these 3 criteria, higher CLM-scores were or tended to be associated with higher QRS scores and incidence of RPEMI. In multivariate analyses including no-reflow phenomenon and final coronary-flow deterioration, increased CLM-score (≥2) was independently associated with high QRS scores and RPEMI (odd ratio 11.25 [95% CI, 2.43–52.00]; P =0.002).

Conclusions:

Vulnerable CLM was a consistent determinant of advanced myocardial injury/infarction both before and after reperfusion therapy and may play a pivotal role in the development of RPEMI.

DOI： 10.1161/circimaging.122.014497

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Prognostic impact of upper and lower extremity muscle mass in heart failure. International journal

Masaaki Konishi, Eiichi Akiyama, Yasushi Matsuzawa, Ryosuke Sato, Shinnosuke Kikuchi, Hidefumi Nakahashi, Kozo Okada, Noriaki Iwahashi, Masami Kosuge, Toshiaki Ebina, Kiyoshi Hibi, Toshihiro Misumi, Kouichi Tamura, Kazuo Kimura

ESC heart failure 10 ( 1 ) 732 - 737 2022.10

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AIMS: Reduced skeletal muscle mass is a major component of sarcopenia, associated with impaired exercise capacity and poor prognosis in patients with heart failure (HF). Measurement of skeletal muscle mass by dual-energy X-ray absorptiometry may be affected by fluid retention, typically in the patients' lower extremities. The aim of the present study was to elucidate the association between upper and lower extremity skeletal muscle mass (USM and LSM) and all-cause mortality in hospitalized patients with HF, after discharge. METHODS: This was a single-centre observational cohort study of 418 patients (59% were men) admitted with a diagnosis of HF (71 ± 13 years), with a left ventricular ejection fraction of 39 ± 16%. USM and LSM were measured by dual-energy X-ray absorptiometry with patients in a stable state after decongestion therapy. RESULTS: The USM and LSM were 5.29 ± 1.18 and 13.78 ± 3.20 kg for men and 3.37 ± 0.68 and 9.19 ± 1.80 kg for women. A positive correlation was obtained between USM and LSM with mid-upper arm circumference (r = 0.684, P < 0.001) and calf circumference (r = 0.822, P < 0.001), respectively. During a median follow-up of 37 months, 92 (22.0%) of the 418 patients died. A Kaplan-Meier analysis revealed that sex-specific quartiles of USM/height2 and LSM/height2 were associated with all-cause mortality (both P < 0.001 by the log-rank test). In Cox models adjusted by age, sex, creatinine, haemoglobin, NYHA class, and height2 , the hazard ratio with 95% confidence intervals for all-cause mortality was 0.557 [0.393-0.783] (P < 0.001) for USM per 1 kg, and 0.783 [0.689-0.891] (P < 0.001) for LSM per 1 kg. The receiver-operator-characteristic curve analysis showed a comparable area under the curve between the USM/height2 and LSM/height2 (0.557 vs. 0.568, P = 0.562) in predicting all-cause mortality. The ratio of USM to LSM was significantly lower in 37 patients with residual leg oedema than in the 360 patients without oedema (36.1% vs. 38.1%, P = 0.004), suggesting the influence of oedema on measured LSM. CONCLUSIONS: Both USM and LSM had a prognostic implication on mortality after discharge in HF, even though LSM may have been affected by leg oedema. These findings indicate that clinicians should not ignore a patient's USM or LSM in the prognostication of patients with HF.

DOI： 10.1002/ehf2.14195

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Post-procedural quantitative flow ratio gradient and target lesion revascularization after drug-coated balloon or plain-old balloon angioplasty. Reviewed International journal

Hidekuni Kirigaya, Kozo Okada, Kiyoshi Hibi, Nobuhiko Maejima, Noriaki Iwahashi, Yasushi Matsuzawa, Yugo Minamimoto, Masami Kosuge, Toshiaki Ebina, Kouichi Tamura, Kazuo Kimura

Journal of cardiology 80 ( 6 ) 511 - 517 2022.7

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BACKGROUND: The optimal endpoint after balloon angioplasty remains poorly defined. This study aimed to characterize post-balloon angioplasty anatomical and physiological indexes by quantitative flow ratio (QFR) and to compare their prognostic impacts on long-term clinical outcomes. METHODS: This retrospective study included 106 lesions from 106 patients who underwent percutaneous coronary interventions with drug-coated-balloon (n = 69) or plain-old-balloon-angioplasty (n = 37). Analyses measured minimum lumen diameter (MLD) and percent diameter stenosis (%DS) as anatomical indexes; QFR of target vessel (QFR-vessel) and QFR-gradient (ΔQFR between proximal and distal segments of the lesion) as physiological indexes. Primary endpoint was target lesion revascularization (TLR) after the index procedure. RESULTS: TLR occurred in 21 (20 %) lesions. TLR group showed significantly smaller QFR-vessel (0.79 ± 0.12 vs. 0.85 ± 0.12, p = 0.03), as well as greater QFR-gradient (0.12 ± 0.07 vs. 0.04 ± 0.03, p < 0.0001) at post-procedure compared with non-TLR group. The percentage of angiographically significant dissection was also more frequently observed in TLR group compared with non-TLR group (47.6 % vs. 14.1 %, p < 0.0001 for log-rank). In the multivariate analysis, angiographically significant dissection and QFR-gradient at post-procedure was significantly associated with TLR. In the receiver-operating characteristics curve analysis, the area under the curve for predicting post-procedural TLR was significantly greater for QFR-gradient than for MLD and residual %DS (p < 0.0001 for MLD and p = 0.0003 for residual %DS at post-procedure). The best cut-off value of post-procedural QFR-gradient for predicting TLR was 0.08. CONCLUSIONS: Post-procedural QFR-gradient across the lesion was a statistically independent and stronger predictor of TLR, compared with anatomical indexes.

DOI： 10.1016/j.jjcc.2022.07.007

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A Simple Risk Score to Differentiate Between Coronary Artery Obstruction and Coronary Artery Spasm of Patients With Acute Coronary Syndrome Without Persistent ST-Segment Elevation.

Masaomi Gohbara, Noriaki Iwahashi, Kozo Okada, Yutaka Ogino, Yohei Hanajima, Jin Kirigaya, Yugo Minamimoto, Yasushi Matsuzawa, Manabu Nitta, Masaaki Konishi, Kiyoshi Hibi, Masami Kosuge, Toshiaki Ebina, Teruyasu Sugano, Toshiyuki Ishikawa, Kouichi Tamura, Kazuo Kimura

Circulation journal : official journal of the Japanese Circulation Society 86 ( 10 ) 1509 - 1518 2022.5

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BACKGROUND: The aim of this study was to create a risk scoring model to differentiate obstructive coronary artery (CA) from CA spasm in the etioology of acute coronary syndrome (ACS).Methods and Results: We included 753 consecutive patients with ACS without persistent ST-segment elevation (p-STE). The exclusion criteria were: (1) out-of-hospital cardiac arrest; (2) cardiogenic shock; (3) hemodialysis; (4) atrial fibrillation/flutter; (5) severe valvular disease; (6) no coronary angiography; (7) non-obstructive coronary artery without "definite" vasospastic angina definition; and/or (8) missing data. From the multivariate logistic regression analysis for prediction of obstructive CA, an integer score of 2 to each 0.5 increment in odds ratio was given, and values were divided into quartiles according to the total score. The scores were as follows: age >70 years (6 points), non-STE myocardial infarction (9 points), diabetes mellitus (5 points), B-type natriuretic peptide >90 pg/mL (7 points), neutrophil to lymphocyte ratio >2 (5 points), and high-density lipoprotein cholesterol <50 mg/dL (5 points). CA spasm-induced ACS occurred in 50.0% in Quartile 1 (total score: 0-13), 20.5% in Quartile 2 (total score: 14-19), 4.9% in Quartile 3 (total score: 20-26), and 2.2% in Quartile 4 (total score: 27-37) (P<0.001), indicating that a total score of <20 was a potential clinical indicator of CA spasm-induced ACS. CONCLUSIONS: CA spasm-induced ACS should be suspected if a total score of <20, and a spasm provocation test was being considered.

DOI： 10.1253/circj.CJ-22-0096

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Impact of Firmicutes to Bacteroidetes Ratio on the Cardiovascular Events in Male Patients with Acute Myocardial Infarction(和訳中)

中橋秀文, 松澤泰志, 日比潔, 岩橋徳明, 岡田興造, 木村裕一郎, 南本祐吾, 荻野尭, 佐藤亮佑, 菊地進之介, 小菅雅美, 田村功一, 木村一雄

日本循環器学会学術集会抄録集 86回 PJ15 - 4 2022.3

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Clinical and Lesion Characteristics of Rapidly Progressive and Extensive Anterior-wall ST-segment Elevation Myocardial Infarction(和訳中)

岡田興造, 日比潔, 菊地進之介, 桐ヶ谷英邦, 花島陽平, 佐藤亮佑, 中橋秀文, 南本勇吾, 松澤泰志, 岩橋徳明, 小菅雅美, 海老名俊明, 田村功一, 木村一雄

日本循環器学会学術集会抄録集 86回 PJ52 - 6 2022.3

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Impact of red blood cell distribution width and mean platelet volume in patients with ST-segment elevation myocardial infarction.

Toshiaki Ebina, Shiori Tochihara, Mai Okazaki, Kazuyo Koike, Yuko Tsuto, Megumi Tayama, Yukiko Takanami, Haruka Hirose, Mutsuo Horii, Kozo Okada, Yasushi Matsuzawa, Nobuhiko Maejima, Noriaki Iwahashi, Kiyoshi Hibi, Masami Kosuge, Kouichi Tamura, Kazuo Kimura

Heart and vessels 37 ( 3 ) 392 - 399 2022.3

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DOI： 10.1007/s00380-021-01936-6

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男性の急性心筋梗塞患者の心血管イベントに対し腸内細菌種のFirmicutesとBacteroidetesの比率が及ぼす影響(Impact of Firmicutes to Bacteroidetes Ratio on the Cardiovascular Events in Male Patients with Acute Myocardial Infarction)

中橋秀文, 松澤泰志, 日比潔, 岩橋徳明, 岡田興造, 木村裕一郎, 南本祐吾, 荻野尭, 佐藤亮佑, 菊地進之介, 小菅雅美, 田村功一, 木村一雄

日本循環器学会学術集会抄録集 86回 PJ15 - 4 2022.3

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Ratio of Left Ventricular Outflow Tract Area and Aortic Annulus Area Predicts Atrioventricular Block in Transcatheter Aortic Valve Implantation(和訳中)

Kikuchi Shinnosuke, Hibi Kiyoshi, Minamimoto Yugo, Cho Tomoki, Terasaka Kengo, Okada Kozo, Matsuzawa Yasushi, Iwahashi Noriaki, Kosuge Masami, Ebina Toshiaki, Uchida Keiji, Tamura Kouichi, Kimura Kazuo

日本循環器学会学術集会抄録集 86回 MPE08 - 6 2022.3

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Angle between Aortic Annulus and Myocardium in LVOT and Artioventricular Block in Patients with Aortic Stenosis Undergoing TAVI(和訳中)

Kikuchi Shinnosuke, Hibi Kiyoshi, Minamimoto Yugo, Cho Tomoki, Terasaka Kengo, Okada Kozo, Matsuzawa Yasushi, Iwahashi Noriaki, Kosuge Masami, Ebina Toshiaki, Uchida Keiji, Tamura Kouichi, Kimura Kazuo

日本循環器学会学術集会抄録集 86回 MPE08 - 9 2022.3

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Feasibility and safety of transradial balloon aortic valvuloplasty in patients with severe aortic stenosis.

Yugo Minamimoto, Kiyoshi Hibi, Jin Kirigaya, Hironori Takahashi, Kensuke Matsushita, Noriaki Iwahashi, Yasushi Matsuzawa, Nobuhiko Maejima, Masami Kosuge, Toshiaki Ebina, Teruyasu Sugano, Toshiyuki Ishikawa, Kouichi Tamura, Kazuo Kimura

Cardiovascular intervention and therapeutics 37 ( 3 ) 558 - 565 2022.1

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DOI： 10.1007/s12928-021-00825-z

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Direct Oral Anticoagulant Therapy for Isolated Distal Deep Vein Thrombosis Associated with Cancer in Routine Clinical Practice. International journal

Yutaka Ogino, Tomoaki Ishigami, Ryosuke Sato, Hidefumi Nakahashi, Yugo Minamimoto, Yuichiro Kimura, Kozo Okada, Yasushi Matsuzawa, Noriaki Iwahashi, Kiyoshi Hibi, Masami Kosuge, Toshiaki Ebina, Toshiyuki Ishikawa, Kouichi Tamura, Kazuo Kimura

Journal of clinical medicine 10 ( 20 ) 2021.10

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DOI： 10.3390/jcm10204648

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Impact of sarcopenic obesity on long-term clinical outcomes after ST-segment elevation myocardial infarction. International journal

Ryosuke Sato, Kozo Okada, Eiichi Akiyama, Masaaki Konishi, Yasushi Matsuzawa, Hidefumi Nakahashi, Yugo Minamimoto, Yuichiro Kimura, Nobuhiko Maejima, Noriaki Iwahashi, Kiyoshi Hibi, Masami Kosuge, Toshiaki Ebina, Kouichi Tamura, Kazuo Kimura

Atherosclerosis 335 135 - 141 2021.10

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DOI： 10.1016/j.atherosclerosis.2021.08.038

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Global Strain Measured by Three-Dimensional Speckle Tracking Echocardiography Is a Useful Predictor for 10-Year Prognosis After a First ST-Elevation Acute Myocardial Infarction.

Noriaki Iwahashi, Jin Kirigaya, Masaomi Gohbara, Takeru Abe, Mutsuo Horii, Yohei Hanajima, Noriko Toya, Hironori Takahashi, Yugo Minamimoto, Yuichiro Kimura, Eiichi Akiyama, Kozo Okada, Yasushi Matsuzawa, Nobuhiko Maejima, Kiyoshi Hibi, Masami Kosuge, Toshiaki Ebina, Kouichi Tamura, Kazuo Kimura

Circulation journal : official journal of the Japanese Circulation Society 85 ( 10 ) 1735 - 1743 2021.9

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BACKGROUND: Three-dimensional (3D) speckle tracking echocardiography (STE) after ST-elevation acute myocardial infarction (STEMI) is associated with left ventricular (LV) remodeling and 1-year prognosis. This study investigated the clinical significance of 3D-STE in predicting the long-term prognosis of patients with STEMI.Methods and Results:A total of 270 patients (mean age 64.6 years) with first-time STEMI treated with reperfusion therapy were enrolled. At 24 h after admission, standard 2D echocardiography and 3D full-volume imaging were performed, and 2D-STE and 3D-STE were calculated. Patients were followed up for a median of 119 months (interquartile range: 96-129 months). The primary endpoint was occurrence of a major adverse cardiac event (MACE: cardiac death, heart failure with hospitalization), and 64 patients experienced MACEs. Receiver operating characteristic curves and Cox hazard multivariate analysis showed that the 3D-STE indices were stronger predictors of MACE compared with those of 2D-STE. Additionally, 3D-global longitudinal strain (GLS) was the strongest predictor for MACE followed by 3D-global circumferential strain (GCS). The Kaplan-Meier curve demonstrated that 3D-GLS >-11.0 was an independent predictor for MACE (log-rank χ2=132.2, P<0.0001). When combined with 3D-GCS >-18.3, patients with higher values of 3D-GLS and 3D-GCS were found to be at extremely high risk for MACE. CONCLUSIONS: Global strain measured by 3D-STE immediately after the onset of STEMI is a clinically significant predictor of 10-year prognosis.

DOI： 10.1253/circj.CJ-21-0183

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急性冠症候群における慢性炎症-フレイル連関と予後への影響

佐藤亮佑, 松澤泰志, 秋山英一, 小西正紹, 吉井智洋, 中橋秀文, 南本祐吾, 木村一雄, 前島信彦, 岩橋徳明, 日比潔, 小菅雅美, 海老名俊明, 田村功一

日本心臓病学会学術集会抄録 69回 O - 248 2021.9

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ST上昇型心筋梗塞におけるprimary PCI中の血小板血栓形成能に及ぼすモルヒネの影響

菊地進之介, 瀧澤良哉, 塚原健吾, 岡田興造, 松澤泰志, 岩橋徳明, 日比潔, 小菅雅美, 海老名俊明, 田村功一, 木村一雄

日本心臓病学会学術集会抄録 69回 O - 063 2021.9

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Clinical Significance of Late Diastolic Tissue Doppler Velocity at 24 Hours or 14 Days After Onset of ST-Elevation Acute Myocardial Infarction.

Noriaki Iwahashi, Masaomi Gohbara, Takeru Abe, Jin Kirigaya, Mutsuo Horii, Yohei Hanajima, Hironori Takahashi, Yugo Minamimoto, Yuichiro Kimura, Eiichi Akiyama, Kozo Okada, Yasushi Matsuzawa, Nobuhiko Maejima, Kiyoshi Hibi, Toshiaki Ebina, Masami Kosuge, Kouichi Tamura, Kazuo Kimura

Circulation reports 3 ( 7 ) 396 - 404 2021.7

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Background: The significance of late diastolic velocity (a') obtained by tissue Doppler imaging (TDI), which reveals atrial function, in ST-elevation myocardial infarction (STEMI) remains unclear. This study evaluated the association of TDI parameters determined either immediately or 2 weeks after percutaneous coronary intervention (PCI) with long-term outcomes. Methods and Results: In all, 740 patients with first-time STEMI underwent immediate PCI (i.e., within 12 h of onset). Echocardiography was performed in 307 patients 2 weeks after onset (Group A; mean age 64 years, 249 males), in 277 patients immediately after PCI (Group B; mean age 65 years, 229 males), and in 156 patients twice (i.e., immediately and 2 weeks after PCI; Group C; mean age 65 years, 135 males). Patients were followed-up for up to 10 years (mean 81 months). The primary endpoints were cardiac death or heart failure hospitalization. Major adverse cardiovascular events (MACE) occurred in 143 patients (19%) during the follow-up period. Both univariate and multivariate Cox hazard analyses were used to determine predictors of MACE. At 24 h and 2 weeks after STEMI onset, a' and E/e' were the strongest predictors of MACE, respectively. Conclusions: TDI parameters have different implications depending on the timing of echocardiography after a first-time STEMI. Based on the results of this study, atrial dysfunction measured by TDI 24 h after STEMI onset may indicate a poor prognosis.

DOI： 10.1253/circrep.CR-21-0056

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Skeletal muscle mass is associated with glycemic variability in patients with ST-segment elevation myocardial infarction.

Masaomi Gohbara, Noriaki Iwahashi, Ryosuke Sato, Eiichi Akiyama, Masaaki Konishi, Hidefumi Nakahashi, Shunsuke Kataoka, Hironori Takahashi, Jin Kirigaya, Yugo Minamimoto, Kozo Okada, Yasushi Matsuzawa, Nobuhiko Maejima, Kiyoshi Hibi, Masami Kosuge, Toshiaki Ebina, Teruyasu Sugano, Toshiyuki Ishikawa, Kouichi Tamura, Kazuo Kimura

Heart and vessels 36 ( 7 ) 945 - 954 2021.7

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DOI： 10.1007/s00380-021-01781-7

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Prognostic impact of muscle and fat mass in patients with heart failure. International journal

Masaaki Konishi, Eiichi Akiyama, Yasushi Matsuzawa, Ryosuke Sato, Shinnosuke Kikuchi, Hidefumi Nakahashi, Nobuhiko Maejima, Noriaki Iwahashi, Masami Kosuge, Toshiaki Ebina, Kiyoshi Hibi, Toshihiro Misumi, Stephan von Haehling, Stefan D Anker, Kouichi Tamura, Kazuo Kimura

Journal of cachexia, sarcopenia and muscle 12 ( 3 ) 568 - 576 2021.6

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DOI： 10.1002/jcsm.12702

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Diagnostic performance and limitation of quantitative flow ratio for functional assessment of intermediate coronary stenosis. International journal

Hidekuni Kirigaya, Kozo Okada, Kiyoshi Hibi, Nobuhiko Maejima, Noriaki Iwahashi, Yasushi Matsuzawa, Eiichi Akiyama, Yugo Minamimoto, Masami Kosuge, Toshiaki Ebina, Kouichi Tamura, Kazuo Kimura

Journal of cardiology 77 ( 5 ) 492 - 499 2021.5

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DOI： 10.1016/j.jjcc.2020.11.002

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Characteristics and Prognosis of Patients with Vasospastic Angina Diagnosed by a Provocation Test with Secondary Prevention Implantable Cardioverter Defibrillator.

Yutaka Ogino, Toshiyuki Ishikawa, Yugo Minamimoto, Masayoshi Kiyokuni, Yuichiro Kimura, Eiichi Akiyama, Kozo Okada, Masaaki Konishi, Junya Hosoda, Yasushi Matsuzawa, Nobuhiko Maejima, Noriaki Iwahashi, Katsumi Matsumoto, Kiyoshi Hibi, Masami Kosuge, Toshiaki Ebina, Kouichi Tamura, Kazuo Kimura

International heart journal 62 ( 2 ) 224 - 229 2021.3

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DOI： 10.1536/ihj.20-360

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ST上昇型急性心筋梗塞後の10年予後を予測する新たな因子としての3Dスペックルトラッキング(Three Dimensional Speckle Tracking as a Novel Predictor of Ten Year Prognosis after ST Elevation Acute Myocardial Infarction)

岩橋徳明, 桐仁, 堀井睦夫, 花島陽平, 岡田興造, 松澤泰志, 前島信彦, 日比潔, 小菅雅美, 海老名俊明, 田村功一, 木村一雄

日本循環器学会学術集会抄録集 85回 OJ50 - 3 2021.3

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心機能および大動脈弁閉鎖不全症は重症大動脈弁狭窄症患者における経カテーテル大動脈弁置換術後の左室リバースリモデリングを予測する(Cardiac Function and Aortic Regurgitation Predict Left Ventricular Reverse-Remodeling after Transcatheter Aortic Valve Replacement in Patients with Severe Aortic Stenosis)

Minamimoto Yugo, Hibi Kiyoshi, Choh Tomoki, Iwahashi Noriaki, Kikuchi Shinnosuke, Kirigaya Jin, Akiyama Eiichi, Okada Kozo, Matsuzawa Yasushi, Maejima Nobuhiko, Kosuge Masami, Ebina Toshiaki, Uchida Keiji, Tamura Kouichi, Kimura Kazuo

日本循環器学会学術集会抄録集 85回 OE136 - 6 2021.3

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再灌流療法を施行するST上昇型急性心筋梗塞患者における発症時ECG所見の臨床的意義(Clinical Implications of ECG Findings at Presentation in Patients with ST-segment Elevation Acute Myocardial Infarction Undergoing Reperfusion Therapy)

小菅雅美, 日比潔, 岩橋徳明, 松澤泰志, 前島信彦, 竹内一郎, 海老名俊明, 田村功一, 木村一雄

日本循環器学会学術集会抄録集 85回 SS13 - 2 2021.3

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急性冠症候群患者におけるアログリプチンを用いた早期介入が冠動脈プラークの退縮および安定化に及ぼす影響(Impact of Early Intervention with Alogliptin on Coronary Plaque Regression and Stabilization in Patients with Acute Coronary Syndromes)

Kikuchi Shinnosuke, Okada Kozo, Hibi Kiyoshi, Nakahashi Hidefumi, Minamimoto Yugo, Kimura Yuichiro, Akiyama Eiichi, Matsuzawa Yasushi, Maejima Nobuhiko, Iwahashi Noriaki, Kosuge Masami, Ebina Toshiaki, Tamura Kouichi, Kimura Kazuo

日本循環器学会学術集会抄録集 85回 FRS1 - 1 2021.3

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ST上昇型心筋梗塞に対する初回経皮的冠動脈インターベンション時の血小板機能に対するプラスグレル塩酸塩口腔内崩壊錠の負荷効果(Loading Effect of Prasugrel Orally Disintegrating Tablet on Platelet Function during Primary Percutaneous Coronary Intervention in ST-segment Elevation Myocardial Infarction)

Kikuchi Shinnosuke, Tsukahara Kengo, Hibi Kiyoshi, Nakahashi Hidefumi, Minamimoto Yugo, Kimura Yuichiro, Akiyama Eiichi, Okada Kozo, Matsuzawa Yasushi, Maejima Nobuhiko, Iwahashi Noriaki, Kosuge Masami, Ebina Toshiaki, Tamura Kouichi, Kimura Kazuo

日本循環器学会学術集会抄録集 85回 OE011 - 6 2021.3

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右室梗塞と乳頭筋断裂による急性僧帽弁逆流を合併した急性心筋梗塞の一例

中山尚貴, 吉井智洋, 松本淳, 南本祐吾, 松澤泰志, 岩橋徳明, 前島信彦, 内田敬二, 日比潔, 木村一雄

日本心血管インターベンション治療学会抄録集 29回 604 - 604 2021.2

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中等度冠動脈病変に対するQFRの有用性と限界

桐ヶ谷英邦, 岡田興造, 日比潔, 前島信彦, 岩橋徳明, 小菅雅美, 田村功一, 木村一雄

日本心血管インターベンション治療学会抄録集 29回 915 - 915 2021.2

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IB-IVUSによる線維性皮膜厚計測の診断精度の検討 OCTとの比較

岡田興造, 日比潔, 前島信彦, 岩橋徳明, 松澤泰志, 秋山英一, 南本勇吾, 田村功一, 木村一雄

日本心血管インターベンション治療学会抄録集 29回 944 - 944 2021.2

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Calcium Arcがバルーン拡張後の石灰化病変のクラック形成を予測するCalcium Thicknessの閾値に及ぼす影響(Influence of Calcium Arc on the Threshold of Calcium Thickness to Predict Crack Formation after Balloon Dilatation in Calcified Lesion)

前島信彦, 日比潔, 菊地進之介, 桐ヶ谷仁, 桐ヶ谷英邦, 佐藤亮佑, 中橋秀文, 南本祐吾, 中山尚貴, 秋山英一, 松澤泰志, 岡田興造, 岩橋徳明, 小菅雅美, 海老名俊明, 木村一雄

日本心血管インターベンション治療学会抄録集 29回 1321 - 1321 2021.2

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Clinical impact of admission urinary 8-hydroxydeoxyguanosine level for predicting cardiovascular mortality in patients with acute coronary syndrome.

Masaomi Gohbara, Noriaki Iwahashi, Hidefumi Nakahashi, Shunsuke Kataoka, Hironori Takahashi, Jin Kirigaya, Yugo Minamimoto, Eiichi Akiyama, Kozo Okada, Yasushi Matsuzawa, Masaaki Konishi, Nobuhiko Maejima, Kiyoshi Hibi, Masami Kosuge, Toshiaki Ebina, Teruyasu Sugano, Toshiyuki Ishikawa, Kouichi Tamura, Kazuo Kimura

Heart and vessels 36 ( 1 ) 38 - 47 2021.1

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DOI： 10.1007/s00380-020-01663-4

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Decreased Appendicular Skeletal Muscle Mass is Associated with Poor Outcomes after ST-Segment Elevation Myocardial Infarction.

Ryosuke Sato, Eiichi Akiyama, Masaaki Konishi, Yasushi Matsuzawa, Hiroyuki Suzuki, Chika Kawashima, Yuichiro Kimura, Kozo Okada, Nobuhiko Maejima, Noriaki Iwahashi, Kiyoshi Hibi, Masami Kosuge, Toshiaki Ebina, Stephan von Haehling, Stefan D Anker, Kouichi Tamura, Kazuo Kimura

Journal of atherosclerosis and thrombosis 27 ( 12 ) 1278 - 1287 2020.12

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DOI： 10.5551/jat.52282

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Efficacy and safety of early initiation of eplerenone treatment in patients with acute heart failure (EARLIER trial): a multicenter, randomized, double-blind, placebo-controlled trial. International journal

Masanori Asakura, Shin Ito, Takahisa Yamada, Yoshihiko Saito, Kazuo Kimura, Akira Yamashina, Atsushi Hirayama, Youichi Kobayashi, Akihisa Hanatani, Mitsuru Tsujimoto, Satoshi Yasuda, Yukio Abe, Yorihiko Higashino, Youdo Tamaki, Hiroshi Sugino, Hiroyuki Niinuma, Yoshitaka Okuhara, Toshimi Koitabashi, Shin-Ichi Momomura, Kuniya Asai, Akihiro Nomura, Hiroya Kawai, Yasuhiro Satoh, Tsutomu Yoshikawa, Ken-Ichi Hirata, Yoshiaki Yokoi, Jun Tanaka, Yoshisato Shibata, Yasuhiro Maejima, Shunsuke Tamaki, Hiroyuki Kawta, Noriaki Iwahashi, Masatake Kobayashi, Yoshiharu Higuchi, Akiko Kada, Haruko Yamamoto, Masafumi Kitakaze

European heart journal. Cardiovascular pharmacotherapy 8 ( 2 ) 108 - 117 2020.11

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AIMS: A mineralocorticoid receptor antagonist (MRA) is effective in patients with chronic heart failure; however, the effects of the early initiation of an MRA in patients with acute heart failure (AHF) have not been elucidated. METHODS AND RESULTS: In this multicenter, randomized, double-blind, placebo-controlled, parallel-group study, we focused on the safety and effectiveness of the treatment with eplerenone, a selective MRA in 300 patients with AHF, that is, 149 in the eplerenone group and 151 in the placebo group in 27 Japanese institutions. The key inclusion criteria were (1) patients aged 20 years or older and (2) those with left ventricular ejection fraction of ≤ 40%. The primary outcome was a composite of cardiac death or first re-hospitalization due to cardiovascular disease within 6 months. The mean age of the participants was 66.8 years, 27.3% were women, and the median levels of brain natriuretic peptide were 376.0 pg/mL. The incidences of the primary outcome were 19.5% in the eplerenone group and 17.2% in the placebo group (hazard ratio (HR): 1.09, 95% confidence interval (CI): 0.642-1.855). In prespecified secondary outcomes, HR for the composite endpoint, cardiovascular death, or first re-hospitalization due to heart failure (HF) within 6 months was 0.55 (95% CI: 0.213 to 1.434). The safety profile for eplerenone was as expected. CONCLUSION: The early initiation of eplerenone in patients with AHF could safely be utilized. The reduction of the incidence of a composite of cardiovascular death or first re-hospitalization for cardiovascular diseases by eplerenone is inconclusive because of inadequate power.

DOI： 10.1093/ehjcvp/pvaa132

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Impact of Myocardial Bridge on Life-Threatening Ventricular Arrhythmia in Patients With Implantable Cardioverter Defibrillator. International journal

Kozo Okada, Kiyoshi Hibi, Yutaka Ogino, Nobuhiko Maejima, Shinnosuke Kikuchi, Hidekuni Kirigaya, Jin Kirigaya, Ryosuke Sato, Hidefumi Nakahashi, Yugo Minamimoto, Yuichiro Kimura, Eiichi Akiyama, Yasushi Matsuzawa, Noriaki Iwahashi, Masami Kosuge, Toshiaki Ebina, Kouichi Tamura, Kazuo Kimura

Journal of the American Heart Association 9 ( 21 ) e017455 2020.11

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DOI： 10.1161/JAHA.120.017455

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Optimal timing of echocardiography for heart failure inpatients in Japanese institutions: OPTIMAL Study. International journal

Hidekazu Tanaka, Yosuke Nabeshima, Tetsuji Kitano, Sakura Nagumo, Miki Tsujiuchi, Mio Ebato, Hiroyuki Mataki, Masanori Takada, Taichi Hayashi, Daisuke Sato, Yoko Miyasaka, Keiko Araki, Noriaki Iwahashi, Masaaki Takeuchi, Satoshi Nakatani

ESC heart failure 7 ( 6 ) 4213 - 4221 2020.10

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AIMS: Guidelines for the diagnosis and treatment of acute and chronic heart failure (HF) provided by the European Society of Cardiology state that echocardiography is recommended for the assessment of the myocardial structure and function of subjects with suspected HF including HF with reduced (HFrEF), mid-range (HFmrEF), and preserved ejection fraction (HFpEF) as class I of recommendation and level C of evidence. However, the impact of timing of echocardiography on survival for hospitalized HF patients or the prevalence of echocardiography during their stay has not yet been fully investigated. Therefore, we designed and conducted a prospective multicentre study, Optimal Timing of Echocardiography for Heart Failure Inpatients in Japanese Institutions (OPTIMAL) study, to investigate and evaluate the prevalence of echocardiography during the in-hospital stay of HF patients, and the impact of timing of echocardiography on their survival. METHODS AND RESULTS: OPTIMAL was based on a nationwide, prospective, multicentre registry at 10 institutions in Japan endorsed by the Japanese Society of Echocardiography. A total of 601 patients hospitalized with HF were enrolled between August 2016 and July 2018 at the participating centres. Their mean age was 73.9 ± 13.0 years, left ventricular ejection fraction was 37.0% (26.0-50.0), and 256 patients (42.6%) were female. Admission echocardiography (admission echo) was categorized as either standard or point-of-care echocardiography performed within 3 days of admission, as was pre-discharge echocardiography (pre-discharge echo) within 3 days of discharge. The primary endpoint was defined as cardiovascular death over a median follow-up period of 18.9 months (9.3-26.5 months). Admission echo was performed for 476 patients (79.2%) and pre-discharge echo for 216 patients (35.9%). The primary endpoint of cardiovascular death occurred in 65 patients (10.8%). Kaplan-Meier curve findings indicated that survival of patients with pre-discharge echo was significantly better than that of patients without it (log-rank P < 0.001), and the same findings were obtained for patients with HFrEF, HFmrEF, and HFpEF. However, survival of patients with and without admission echo was similar (log-rank P = 0.33). CONCLUSIONS: This OPTIMAL study prospectively showed the importance of pre-discharge echo for hospitalized HF patients. Careful attention is needed regarding the haemodynamic status of HF patients by administering pre-discharge echo to avoid HF re-hospitalization after discharge, and pre-discharge echo may provide additional information for deciding the appropriate discharge time. Our findings may thus offer a new insight into the management of hospitalized HF patients.

DOI： 10.1002/ehf2.13050

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Ubiquinol Improves Endothelial Function in Patients with Heart Failure with Reduced Ejection Fraction: A Single-Center, Randomized Double-Blind Placebo-Controlled Crossover Pilot Study. Reviewed International journal

Chika Kawashima, Yasushi Matsuzawa, Masaaki Konishi, Eiichi Akiyama, Hiroyuki Suzuki, Ryosuke Sato, Hidefumi Nakahashi, Shinnosuke Kikuchi, Yuichiro Kimura, Nobuhiko Maejima, Noriaki Iwahashi, Kiyoshi Hibi, Masami Kosuge, Toshiaki Ebina, Kouichi Tamura, Kazuo Kimura

American journal of cardiovascular drugs : drugs, devices, and other interventions 20 ( 4 ) 363 - 372 2020.8

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DOI： 10.1007/s40256-019-00384-y

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Direct Oral Anticoagulant Therapy for Cancer-Associated Venous Thromboembolism in Routine Clinical Practice.

Yutaka Ogino, Tomoaki Ishigami, Yugo Minamimoto, Yuichiro Kimura, Eiichi Akiyama, Kozo Okada, Yasushi Matsuzawa, Nobuhiko Maejima, Noriaki Iwahashi, Kiyoshi Hibi, Masami Kosuge, Toshiaki Ebina, Toshiyuki Ishikawa, Kouichi Tamura, Kazuo Kimura

Circulation journal : official journal of the Japanese Circulation Society 84 ( 8 ) 1330 - 1338 2020.7

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DOI： 10.1253/circj.CJ-20-0084

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医療の質を担保した循環器診療における働き方改革単独主治医システムと複数主治医システムにおける時間外労働の比較 YCU病院経営プログラム下でのシミュレーション研究(Overtime Work in Single- versus Multiple-attending Doctor System: A Simulation Study under the YCU Hospital Management Program)

小西正紹, 秋山英一, 岡田興造, 松澤泰志, 木村裕一郎, 前島信彦, 岩橋徳明, 日比潔, 田村功一, 後藤隆久, 木村一雄

日本循環器学会学術集会抄録集 84回シンポジウム6 - 3 2020.7

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循環器診療における包括的心臓リハビリテーションの役割心筋梗塞および心不全患者に対する包括的心臓リハビリテーションにおける栄養指標としての骨格筋の役割(Role of Skeletal Muscle as an Indicator of Nutrition in Comprehensive Cardiac Rehabilitation in Myocardial Infarction and Heart Failure)

佐藤亮佑, 秋山英一, 小西正紹, 松澤泰志, 木村裕一郎, 前島信彦, 岩橋徳明, 日比潔, 小菅雅美, 海老名俊明, 田村功一, 木村一雄

日本循環器学会学術集会抄録集 84回シンポジウム13 - 3 2020.7

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心筋梗塞後のフレイル評価指標としての内皮機能と歩行速度との関連(Association between Endothelial Function and Gait Speed as a Measure of Frailty after Myocardial Infarction)

中橋秀文, 松澤泰志, 日比潔, 岩橋徳明, 前島信彦, 岡田興造, 秋山英一, 南本祐吾, 荻野尭, 佐藤亮佑, 小菅雅美, 田村功一, 木村一雄

日本循環器学会学術集会抄録集 84回 PJ1 - 6 2020.7

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ST上昇型心筋梗塞患者における一次経皮的冠動脈インターベンション時の血小板血栓形成能と白血球増加との関連(Association between Platelet Thrombus Formation Ability during Primary Percutaneous Coronary Intervention and Increased Leukocyte in Patients with ST-elevation Myocardial Infarction)

菊地進之介, 塚原健吾, 市川晋也, 南本祐吾, 荻野尭, 秋山英一, 木村裕一郎, 岡田興造, 松澤泰志, 前島信彦, 岩橋徳明, 日比潔, 小菅雅美, 海老名俊明, 田村功一, 木村一雄

日本循環器学会学術集会抄録集 84回 PJ12 - 6 2020.7

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Impact of serum lipoprotein (a) level on coronary plaque progression and cardiovascular events in statin-treated patients with acute coronary syndrome: a yokohama-acs substudy. International journal

Kensuke Matsushita, Kiyoshi Hibi, Naohiro Komura, Yuichiro Kimura, Yasushi Matsuzawa, Masaaki Konishi, Nobuhiko Maejima, Noriaki Iwahashi, Masami Kosuge, Toshiaki Ebina, Kouichi Tamura, Kazuo Kimura

Journal of cardiology 76 ( 1 ) 66 - 72 2020.7

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BACKGROUND: Lipoprotein (a) [Lp(a)] has been reported to be a residual risk factor in patients who have achieved target lipid levels. The aim of the present study was to investigate the associations of Lp(a) with plaque progression and major cardiovascular events in patients with acute coronary syndromes (ACS). METHODS: The Yokohama-ACS study included 102 patients with ACS who underwent intravascular ultrasound (IVUS) at baseline and at 10-month follow-up after percutaneous coronary intervention (PCI). The patients were randomly assigned to receive either moderate- or low-intensity statin therapy. IVUS was performed to measure the plaque volume at non-culprit lesions. We enrolled 76 patients for whom Lp(a) levels at 10-month follow-up were available. RESULTS: The patients were divided into 2 groups according whether their Lp(a) levels were ≤20 mg/dl [low Lp(a) group; n = 49] or >20 mg/dl [high Lp(a) group; n = 27]. Baseline characteristics and low-density lipoprotein cholesterol levels at 10-month follow-up were similar in the low Lp(a) group and high Lp(a) group (87 ± 29 mg/dl vs. 93 ± 27 mg/dl, p = 0.42). The low Lp(a) group had significant plaque regression, whereas the high Lp(a) group showed slight plaque progression (-6.8% vs. 2.5%, p = 0.02). Ninety-five percent of the prognostic data were obtained 5 years after PCI. The cumulative event-free survival rate was significantly lower in the high Lp(a) group (p = 0.02; log-rank test). CONCLUSIONS: Lp(a) levels may be an alternative predictor of further plaque regression and the likelihood of major adverse cardiovascular events in statin-treated ACS patients.

DOI： 10.1016/j.jjcc.2020.01.005

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急性冠症候群後の肥満非糖尿病患者における血糖変動と糖代謝の相関(Correlation between Glycemic Variability and Glucose Metabolism in Obese Non-diabetic Patients after Acute Coronary Syndrome)

花島陽平, 岩橋徳明, 桐ヶ谷仁, 堀井睦夫, 南本祐吾, 秋山英一, 岡田興造, 松澤泰志, 前島信彦, 日比潔, 小菅雅美, 海老名俊明, 田村功一, 木村一雄

日本循環器学会学術集会抄録集 84回 PJ25 - 5 2020.7

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Platelet-Derived Thrombogenicity Measured by Total Thrombus-Formation Analysis System in Patients With ST-Segment Elevation Myocardial Infarction Undergoing Primary Percutaneous Coronary Intervention.

Shinnosuke Kikuchi, Kengo Tsukahara, Shinya Ichikawa, Takeru Abe, Yugo Minamimoto, Yuichiro Kimura, Eiichi Akiyama, Naoki Nakayama, Kozo Okada, Yasushi Matsuzawa, Masaaki Konishi, Nobuhiko Maejima, Noriaki Iwahashi, Kiyoshi Hibi, Masami Kosuge, Toshiaki Ebina, Kouichi Tamura, Kazuo Kimura

Circulation journal : official journal of the Japanese Circulation Society 84 ( 6 ) 975 - 984 2020.5

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DOI： 10.1253/circj.CJ-19-1043

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二次予防にICD移植を受けた冠血管攣縮性狭心症症例の臨床的特徴器質的冠動脈狭窄症例との比較

荻野尭, 木村一雄, 日比潔, 岩橋徳明, 松澤泰志, 前島信彦, 岡田興造, 木村裕一郎, 秋山英一, 南本祐吾, 佐藤亮祐, 中橋秀文, 桐ヶ谷仁, 桐ヶ谷英邦, 堤勝彦

日本冠疾患学会誌 ( Suppl.2019 ) 159 - 159 2019.12

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透析患者におけるQFRを用いた機能的虚血評価の有効性に関する研究

桐ヶ谷英邦, 岡田興造, 日比潔, 前島信彦, 岩橋徳明, 小菅雅美, 海老名俊明, 田村功一, 木村一雄

日本冠疾患学会誌 ( Suppl.2019 ) 158 - 158 2019.12

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Clinical Impact of Glycemic Variability on Left Ventricular Dysfunction Ata Chronic Phase in Patients Witha First St-segment Elevation Myocardial Infarction

Jin Kirigaya, Jin Kirigaya, Noriaki Iwahashi, Masaomi Gohbara, Eiichi Akiyama, Kozo Okada, Yasushi Matsuzawa, Nobuhiko Maejima, Kiyoshi Hibi, Masami Kosuge, Toshiaki Ebina, Kouichi Tamura, Kazuo Kimura

CIRCULATION 140 2019.11

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The Impact of Arterial Stiffness Assessed by Cardio-ankle Vascular Index on Long-term Outcome in Patients With Acute Coronary Syndrome

Jin Kirigaya, Noriaki Iwahashi, Masaomi Gohbara, Eiichi Akiyama, Kozo Okada, Yasushi Matsuzawa, Nobuhiko Maejima, Kiyoshi Hibi, Masami Kosuge, Toshiaki Ebina, Kouichi Tamura, Kazuo Kimura

CIRCULATION 140 2019.11

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Prognostic Value of Skeletal Muscle Loss With Abnormal Abdominal Fat Distribution in Patients With St-segment Elevation Myocardial Infarction

Ryosuke Satou, Kozo Okada, Eiichi Akiyama, Yasushi Matsuzawa, Masaaki Konishi, Nobuhiko Maejima, Noriaki Iwahashi, Kiyoshi Hibi, Masami Kosuge, Kouichi Tamura, Toshiaki Ebina, Kazuo Kimura

CIRCULATION 140 2019.11

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心破裂を来したたこつぼ症候群の1例

水上紗緒里, 桐ヶ谷英邦, 松澤泰志, 岩橋徳明, 前島信彦, 岡田興造, 秋山英一, 日比潔, 小菅雅美, 木村一雄

日本内科学会関東地方会 654回 33 - 33 2019.10

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Feasibility of IVUS-Derived FFR as a Novel Technique to Estimate Functional Severity of Coronary Stenosis

Kuninobu Kashiyama, Shinjo Sonoda, Kensuke Matsushita, Kozo Okada, Eiichi Akiyama, Yasushi Matsuzawa, Nobuhiko Maejima, Noriaki Iwahashi, Kengo Tsukahara, Masami Kosuge, Toshiaki Ebina, Kiyoshi Hibi, Kouichi Tamura, Kazuo Kimura, M. Brooke Hollak, Paul G. Yock, Alan C. Yeung, Yasuhiro Honda

JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY 74 ( 13 ) B325 - B325 2019.10

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DOI： 10.1016/j.jacc.2019.08.407

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Association Between Platelet Aggregability During Primary Percutaneous Coronary Intervention and Increased Leukocyte in Patients With ST-Segment Elevation Myocardial Infarction

Shinnosuke Kikuchi, Kengo Tsukahara, Shinya Ichikawa, Eiichi Akiyama, Kozo Okada, Yasushi Matsuzawa, Nobuhiko Maejima, Noriaki Iwahashi, Kiyoshi Hibi, Masami Kosuge, Toshiaki Ebina, Kouichi Tamura, Kazuo Kimura

JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY 74 ( 13 ) B160 - B160 2019.10

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DOI： 10.1016/j.jacc.2019.08.215

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Impact of Early Intervention With Alogliptin on Coronary Plaque Regression in Patients with Acute Coronary Syndromes: A Prospective, Single-Center, Randomized Trial

Shinnosuke Kikuchi, Kozo Okada, Kiyoshi Hibi, Naoki Nakayama, Eiichi Akiyama, Yasushi Matsuzawa, Nobuhiko Maejima, Noriaki Iwahashi, Masami Kosuge, Toshiaki Ebina, Kouichi Tamura, Kazuo Kimura

JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY 74 ( 13 ) B818 - B818 2019.10

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DOI： 10.1016/j.jacc.2019.08.984

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Quantitative Flow Ratio for Assessment of Nonculprit Coronary Lesions in Patients With ST-Segment Elevation Myocardial Infarction

Hidekuni Kirigaya, Kozo Okada, Kiyoshi Hibi, Eiichi Akiyama, Yasushi Matsuzawa, Noriaki Iwahashi, Nobuhiko Maejima, Masami Kosuge, Kazuo Kimura

JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY 74 ( 13 ) B323 - B323 2019.10

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DOI： 10.1016/j.jacc.2019.08.405

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Urgent Control of Rapid Atrial Fibrillation by Landiolol in Patients With Acute Decompensated Heart Failure With Severely Reduced Ejection Fraction.

Noriaki Iwahashi, Hironori Takahashi, Takeru Abe, Kozo Okada, Eiichi Akiyama, Yasushi Matsuzawa, Masaaki Konishi, Nobuhiko Maejima, Kiyoshi Hibi, Masami Kosuge, Toshiaki Ebina, Kouichi Tamura, Kazuo Kimura

Circulation reports 1 ( 10 ) 422 - 430 2019.9

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Background: We investigated the clinical usefulness of landiolol for rapid atrial fibrillation (AF) in patients with acute decompensated heart failure (ADHF) and identify the patients eligible for landiolol. Methods and Results: A total of 101 ADHF patients with reduced ejection fraction (HFrEF) with rapid AF were enrolled. Immediately after admission, an initial dose of landiolol was given (1 μg/kg-1/min-1), and then the dose was increased to decrease heart rate (HR) to <110 beats/min and change HR (∆HR) >20% in ≤24 h. Thirty-seven were monitored using right heart catheterization at 3 points (baseline, 1 μg/kg-1/min-1, and maximum dose). We checked the major adverse events (MAE) during initial hospitalization, which included cardiac death, HF prolongation (required i.v. treatment at 30 days), and worsening renal function. The average maximum dose of landiolol was 3.8±2.3 μg/kg-1/min-1. HR (P<0.0001) and pulmonary capillary wedge pressure (P=0.0008) decreased safely. MAE occurred in 39 patients. The patients with left ventricular (LV) end-diastolic volume index <84.0 mL/m2 and mean blood pressure (mean BP) >97 mmHg had less frequent MAE (P<0.0001). Conclusions: Landiolol was effective for safely controlling rapid AF in patients with HFrEF with ADHF, leading to hemodynamic improvement and avoidance of short-term MAE, especially in patients with relatively smaller LV and higher BP.

DOI： 10.1253/circrep.CR-19-0076

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高齢者冠動脈疾患と多臓器連関冠動脈疾患の各ステージにおける心・骨格筋・脂肪関連

佐藤亮佑, 小西正紹, 秋山英一, 松澤泰志, 岡田興造, 前島信彦, 岩橋徳明, 日比潔, 小菅雅美, 海老名俊明, 田村功一, 木村一雄

日本心臓病学会学術集会抄録 67回 S15 - 2 2019.9

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実臨床におけるVTEに対するDOAC治療横浜市立大学附属2病院での検討

荻野尭, 木村一雄, 小菅雅美, 海老名俊明, 日比潔, 岩橋徳明, 松澤泰志, 岡田興造, 秋山英一, 石川利之, 木村裕一郎, 前島信彦, 南本祐吾

日本心臓病学会学術集会抄録 67回 O - 128 2019.9

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ST上昇型急性心筋梗塞患者における体組成の予後への影響

佐藤亮佑, 秋山英一, 松澤泰志, 小西正紹, 木村裕一郎, 岡田興造, 前島信彦, 岩橋徳明, 日比潔, 小菅雅美, 海老名俊明, 田村功一, 木村一雄

日本心臓病学会学術集会抄録 67回 O - 357 2019.9

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耐糖能障害を有する急性冠症候群における持続血糖モニタリングシステムにて計測した血糖変動と予後の検討

花島陽平, 高橋広軌, 岩橋徳明, 桐ヶ谷仁, 秋山英一, 木村裕一郎, 岡田興造, 松澤泰志, 前島信彦, 小菅雅美, 日比潔, 海老名俊明, 田村功一, 木村一雄

日本心臓病学会学術集会抄録 67回 O - 377 2019.9

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循環器医が考える糖尿病管理の未来像急性冠症候群症例において血糖変動は重要な予後規定因子である

岩橋徳明, 松澤泰志, 前島信彦, 小菅雅美, 日比潔, 海老名俊明, 田村功一, 木村一雄

日本心臓病学会学術集会抄録 67回 SS - 4 2019.9

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透析患者における体液シフト心不全患者での考察

小西正紹, 秋山英一, 松澤泰志, 佐藤亮佑, 岡田興造, 岩橋徳明, 日比潔, 海老名俊明, 小菅雅美, 前島信彦, 田村功一, 木村一雄

日本心臓病学会学術集会抄録 67回 SS - 4 2019.9

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Microbiota-derived Trimethylamine N-oxide Predicts Cardiovascular Risk After STEMI. Reviewed International journal

Yasushi Matsuzawa, Hidefumi Nakahashi, Masaaki Konishi, Ryosuke Sato, Chika Kawashima, Shinnosuke Kikuchi, Eiichi Akiyama, Noriaki Iwahashi, Nobuhiko Maejima, Kozo Okada, Toshiaki Ebina, Kiyoshi Hibi, Masami Kosuge, Tomoaki Ishigami, Kouichi Tamura, Kazuo Kimura

Scientific reports 9 ( 1 ) 11647 - 11647 2019.8

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DOI： 10.1038/s41598-019-48246-6

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Acute anterior myocardial infarction with pectus carinatum. Reviewed

Kikuchi S, Nakahashi H, Kimura Y, Akiyama E, Okada K, Matsuzawa Y, Konishi M, Maejima N, Iwahashi N, Hibi K, Kosuge M, Ebina T, Tamura K, Kimura K

Journal of electrocardiology 55 51 - 53 2019.7

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DOI： 10.1016/j.jelectrocard.2019.04.004

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Comparison between instantaneous wave-free ratio versus morphometric assessments by intracoronary imaging. Reviewed

Kensuke Matsushita, Kiyoshi Hibi, Kozo Okada, Kentaro Sakamaki, Eiichi Akiyama, Yuichiro Kimura, Yasushi Matsuzawa, Nobuhiko Maejima, Noriaki Iwahashi, Kengo Tsukahara, Masami Kosuge, Toshiaki Ebina, Peter J Fitzgerald, Yasuhiro Honda, Kouichi Tamura, Kazuo Kimura

Heart and vessels 34 ( 6 ) 926 - 935 2019.6

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DOI： 10.1007/s00380-018-1320-4

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Impact of Total Antithrombotic Effect on Bleeding Complications in Patients Receiving Multiple Antithrombotic Agents. Reviewed

Shinya Ichikawa, Kengo Tsukahara, Shinnosuke Kikuchi, Yugo Minamimoto, Yuichiro Kimura, Kozo Okada, Yasushi Matsuzawa, Masaaki Konishi, Nobuhiko Maejima, Noriaki Iwahashi, Kiyoshi Hibi, Masami Kosuge, Toshiaki Ebina, Kouichi Tamura, Kazuo Kimura

Circulation journal : official journal of the Japanese Circulation Society 83 ( 6 ) 1309 - 1316 2019.5

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DOI： 10.1253/circj.CJ-18-1236

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初回ST部分上昇型心筋梗塞の患者における入院6時間後の高血糖は梗塞サイズを予測する(Hyperglycemia at 6 Hours can Predict Infarct Size in Patients with a First-time ST Elevation Acute Myocardial Infarction)

堀井睦夫, 岩橋徳明, 桐ヶ谷仁, 高橋広軌, 中山尚貴, 秋山英一, 木村裕一郎, 岡田興造, 松澤泰志, 小西正紹, 前島信彦, 小菅雅美, 日比潔, 海老名俊明, 田村功一, 木村一雄

日本循環器学会学術集会抄録集 83回 PJ002 - 5 2019.3

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ST上昇型心筋梗塞患者における睡眠呼吸障害と造影剤誘発性腎障害との関連(Association between Sleep-disordered Breathing and Contrast-Induced Nephropathy in Patients with ST-Segment Elevation Myocardial Infarction)

桐ヶ谷仁, 岩橋徳明, 岡田興造, 松澤泰志, 小西正紹, 前島信彦, 小菅雅美, 日比潔, 海老名俊明, 田村功一, 木村一雄

日本循環器学会学術集会抄録集 83回 PJ039 - 7 2019.3

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内皮機能および心血管リスクの線形用量反応関係(A Linear dose-Response Relationship between Endothelial Function and Cardiovascular Risk)

松澤泰志, 杉山正悟, 小西正紹, 秋山英一, 佐藤亮佑, 中橋秀文, 日比潔, 岩橋徳明, 前島信彦, 岡田興造, 小菅雅美, 田村功一, 木村一雄

日本循環器学会学術集会抄録集 83回 PJ045 - 6 2019.3

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ST上昇型心筋梗塞患者におけるサルコペニアの要素と内皮機能障害との関係(Relationship between Components of Sarcopenia and Endothelial Dysfunction in Patients with ST-segment Elevation Myocardial Infarction)

佐藤亮佑, 松澤泰志, 秋山英一, 小西正紹, 中橋秀文, 木村裕一郎, 岡田興造, 前島信彦, 岩橋徳明, 小菅雅美, 海老名俊明, 日比潔, 田村功一, 木村一雄

日本循環器学会学術集会抄録集 83回 PJ047 - 6 2019.3

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急性冠症候群後の心血管イベントを予測する心臓足首血管指数とGRACEリスクスコアの併用評価の有用性(Usefulness of Combined Assessments of Cardioankle Vascular Index and GRACE Risk Score for Predicting Cardiovascular Events after Acute Coronary Syndrome)

桐ヶ谷仁, 岩橋徳明, 岡田興造, 松澤泰志, 小西正紹, 前島信彦, 小菅雅美, 日比潔, 海老名俊明, 田村功一, 木村一雄

日本循環器学会学術集会抄録集 83回 PJ086 - 5 2019.3

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ST上昇型心筋梗塞患者において8-hydroxy-2-deoxyguanosineはPrimary PCI後の梗塞サイズと関連する(8-hydroxy-2-deoxyguanosine is Relevant to Infarct Size after Primary Percutaneous Coronary Intervention in Patients with ST-segment Elevation Myocardial Infarction)

南本祐吾, 岩橋徳明, 中橋秀文, 松澤泰志, 小西正紹, 前島信彦, 日比潔, 小菅雅美, 海老名俊明, 田村功一, 木村一雄

日本循環器学会学術集会抄録集 83回 OJ15 - 9 2019.3

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CHARACTERISTIC AND PROGNOSIS OF VASOSPASTIC ANGINA PATIENTS WITH IMPLANTABLE CARDIOVERTER DEFIBRILLATOR FOR SECONDARY PREVENTION: COMPARISON WITH ORGANIC CORONARY STENOSIS

Yutaka Ogino, Kazuo Kimura, Kiyoshi Hibi, Yasushi Matsuzawa, Noriaki Iwahashi, Nobuhiko Maejima, Masami Kosuge, Toshiaki Ebina, Masaaki Konishi

JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY 73 ( 9 ) 487 - 487 2019.3

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DOI： 10.1016/S0735-1097(19)31095-2

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ST上昇型心筋梗塞患者の上肢および下肢における骨格筋量の予後に対する作用(Prognostic Effect of Skeletal Muscle Mass in Upper and Lower Extremities in Patients with ST-segment Elevation Myocardial Infarction)

佐藤亮佑, 秋山英一, 小西正紹, 松澤泰志, 木村裕一郎, 岡田興造, 前島信彦, 岩橋徳明, 小菅雅美, 海老名俊明, 日比潔, 田村功一, 木村一雄

日本循環器学会学術集会抄録集 83回 OJ15 - 7 2019.3

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Association of endothelial function with thin-cap fibroatheroma as assessed by optical coherence tomography in patients with acute coronary syndromes. Reviewed International journal

Yasushi Matsuzawa, Kiyoshi Hibi, Kenichiro Saka, Masaaki Konishi, Eiichi Akiyama, Naoki Nakayama, Toshiaki Ebina, Masami Kosuge, Noriaki Iwahashi, Nobuhiko Maejima, Kouichi Tamura, Kazuo Kimura

Therapeutics and clinical risk management 15 285 - 291 2019

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DOI： 10.2147/TCRM.S184457

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Myocardial Infarction Caused by Accelerated Plaque Formation Related to Myocardial Bridge in a Young Man. Reviewed International journal

Shinnosuke Kikuchi, Kozo Okada, Kiyoshi Hibi, Nobuhiko Maejima, Yasushi Matsuzawa, Masaaki Konishi, Yuichiro Kimura, Masami Kosuge, Noriaki Iwahashi, Toshiaki Ebina, Kouichi Tamura, Kazuo Kimura

The Canadian journal of cardiology 34 ( 12 ) 1687.e13-1687.e15 - 1687.e15 2018.12

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DOI： 10.1016/j.cjca.2018.08.023

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Glycemic Variability Immediately After Hospitalization Can Predict Left Ventricle Remodeling in ST-Segment Elevation Myocardial Infarction Patients

Takahashi Hironori, Noriaki Iwahashi, Kozo Okada, Yasushi Matsuzawa, Masaaki Konishi, Nobuhiko Maejima, Kiyoshi Hibi, Masami Kosuge, Toshiaki Ebina, Kouichi Tamura, Kazuo Kimura

CIRCULATION 138 2018.11

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Prognostic Impact of Muscle, Fat, and Bone Mass in Patients With Heart Failure

Masaaki Konishi, Eiichi Akiyama, Yasushi Matsuzawa, Ryosuke Sato, Hidefumi Nakahashi, Shinnnosuke Kikuchi, Nobuhiko Maejima, Noriaki Iwahashi, Kiyoshi Hibi, Masami Kosuge, Kouichi Tamura, Kazuo Kimura

CIRCULATION 138 2018.11

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頸動脈ステント留置術後に発症した冠攣縮性狭心症の1例

藤野洋平, 松澤泰志, 木村裕一郎, 小西正紹, 前島信彦, 岩橋徳明, 日比潔, 小菅雅美, 海老名俊明, 田村功一, 木村一雄

日本心臓病学会学術集会抄録 66回 EP - 266 2018.9

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超高齢社会における循環器疾患管理におけるフレイルの意義を考える高齢心筋梗塞患者における歩行スピードで評価したフレイルの重要性

松澤泰志, 小西正紹, 佐藤亮祐, 中橋秀文, 川島千佳, 菊地進之介, 前島信彦, 岩橋徳明, 日比潔, 海老名俊明, 小菅雅美, 田村功一, 木村一雄

日本心臓病学会学術集会抄録 66回 S19 - 5 2018.9

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Relationship between enzymatic infarct size and total platelet aggregability during primary percutaneous coronary intervention in patients with ST-elevation myocardial infarction

Shinnosuke Kikuchi, Kengo Tsukahara, Shinya Ichikawa, Yugo Minamimoto, Kozo Okada, Yasushi Matsuzawa, Masaaki Konishi, Nobuhiko Maejima, Noriaki Iwahashi, Kiyoshi Hibi, Masami Kosuge, Toshiaki Ebina, Kouichi Tamura, Kazuo Kimura

JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY 72 ( 13 ) B313 - B313 2018.9

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DOI： 10.1016/j.jacc.2018.08.2016

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Clinical predictors of discordance between instantaneous wavefree ratio and fractional flow reserve

Hidekuni Kirigaya, Kensuke Matsushita, Kozo Okada, Noriaki Iwahashi, Nobuhiko Maejima, Toshiaki Ebina, Kouichi Tamura, Kiyoshi Hibi, Kazuo Kimura

JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY 72 ( 13 ) B65 - B65 2018.9

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DOI： 10.1016/j.jacc.2018.08.1261

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急性心筋梗塞において高インスリン血症/インスリン抵抗性は左室リモデリングの危険因子である

岩橋徳明, 松澤泰志, 小西正紹, 前島信彦, 日比潔, 小菅雅美, 海老名俊明, 田村功一, 木村一雄

日本心臓病学会学術集会抄録 66回 EP - 010 2018.9

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不安定狭心症を契機に高安動脈炎の診断となった高齢女性の1例

菊地進之介, 岡田興造, 木村裕一郎, 松澤泰志, 小西正紹, 前島信彦, 岩橋徳明, 日比潔, 小菅雅美, 海老名俊明, 田村功一, 木村一雄

日本心臓病学会学術集会抄録 66回 EP - 067 2018.9

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ST上昇型急性心筋梗塞において血糖変動が慢性期の左室収縮能に与える影響 2Dスペックルトラッキング法による検討

桐ヶ谷仁, 岩橋徳明, 松澤泰志, 小西正紹, 小菅雅美, 日比潔, 海老名俊明, 木村一雄, 田村功一

日本心臓病学会学術集会抄録 66回 P - 023 2018.9

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Glycemic variability determined with a continuous glucose monitoring system can predict prognosis after acute coronary syndrome. Reviewed International journal

Hironori Takahashi, Noriaki Iwahashi, Jin Kirigaya, Shunsuke Kataoka, Yugo Minamimoto, Masaomi Gohbara, Takeru Abe, Kozo Okada, Yasushi Matsuzawa, Masaaki Konishi, Nobuhiko Maejima, Kiyoshi Hibi, Masami Kosuge, Toshiaki Ebina, Kouichi Tamura, Kazuo Kimura

Cardiovascular diabetology 17 ( 1 ) 116 - 116 2018.8

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BACKGROUND: Impaired glucose metabolism is an established risk factor for coronary artery disease. Previous studies revealed that glycemic variability (GV) is also important for glucose metabolism in patients with acute coronary syndrome (ACS). We explored the association between GV and prognosis in patients with ACS. METHODS: A total of 417 patients with ACS who received reperfusion wore a continuous glucose monitoring system (CGMS) in a stable phase after admission and were monitored for at least 24 consecutive h. The mean amplitude of glycemic excursion (MAGE) was calculated as a marker of GV. We divided into two groups based on the highest tertile levels of MAGE (MAGE = 52 mg/dl). The groups were followed up for a median of 39 months [IQR 24-50 months]. The primary endpoint was the incidence of major adverse cardiovascular and cerebrovascular events (MACCE). RESULT: During follow-up, 66 patients experienced MACCE (5 patients had cardiovascular death, 14 had recurrence of ACS, 27 had angina requiring revascularization, 8 had acute decompensated heart failure, and 16 had a stroke). MACCE was more frequently observed in the high MAGE group (23.5% vs. 11.6%, p = 0.002). In multivariate analysis, high MAGE was an independent predictive factor of poor prognosis for MACCE (odds ratio, 1.84; 95% confidence interval, 1.01-3.36; p = 0.045). CONCLUSION: Glycemic variability determined with a CGMS is a predictor of prognosis in patients with ACS without severe DM. Trial registration UMIN 000010620. Registered April 1st 2012.

DOI： 10.1186/s12933-018-0761-5

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ST上昇型心筋梗塞に対するprimary PCI中の血小板凝集能と酵素梗塞サイズの関係

菊地進之介, 塚原健吾, 岡田興造, 木村裕一郎, 松澤泰志, 小西正紹, 前島信彦, 岩橋徳明, 日比潔, 小菅雅美, 海老名俊明, 田村功一, 木村一雄

日本心血管インターベンション治療学会抄録集 27回 MO455 - MO455 2018.8

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重症大動脈弁狭窄症患者に対する経橈骨動脈大動脈弁拡張術の可能性、有効性、安全性

南本祐吾, 日比潔, 松下絢介, 岩橋徳明, 松澤泰志, 前島信彦, 小菅雅美, 海老名俊明, 木村一雄

日本心血管インターベンション治療学会抄録集 27回 MO278 - MO278 2018.8

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急性心筋梗塞患者ではtrimethylamine N-oxide増加が冠動脈複雑プラークの進行と関連する(The Increase in Trimethylamine N-oxide is Associated with the Progression of Coronary Plaque Complexity in Patients with Acute Myocardial Infarction) Reviewed

中橋秀文, 松澤泰志, 日比潔, 岩橋徳明, 前島信彦, 小西正紹, 木村裕一郎, 小菅雅美, 田村功一, 木村一雄

日本循環器学会学術集会抄録集 82回 OJ16 - 6 2018.3

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初期経皮的冠動脈インターベンションと待機的経皮的冠動脈インターベンションを受けた患者に対するprasugrel初回投与後の血小板凝集性の比較(Comparison of Platelet Aggregability after a Loading Dose of Prasugrel in Patients Undergoing Primary versus Elective Percutaneous Coronary Intervention)

Kikuchi Shinnosuke, Tsukahara Kengo, Kimura Yuichiro, Matsuzawa Yasushi, Maejima Nobuhiko, Iwahashi Noriaki, Hibi Kiyoshi, Kosuge Masami, Ebina Toshiaki, Tamura Koichi, Kimura Kazuo

日本循環器学会学術集会抄録集 82回 OE43 - 7 2018.3

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ST上昇型心筋梗塞患者において糖尿病が血小板凝集性に及ぼす影響(The Influence of Diabetes on Platelet Aggregability in Patients with ST-elevation Myocardial Infarction)

Kikuchi Shinnosuke, Tsukahara Kengo, Kimura Yuichiro, Matsuzawa Yasushi, Maejima Nobuhiko, Iwahashi Noriaki, Hibi Kiyoshi, Kosuge Masami, Ebina Toshiaki, Tamura Koichi, Kimura Kazuo

日本循環器学会学術集会抄録集 82回 OE75 - 9 2018.3

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ST部分上昇型心筋梗塞後の高齢フレイル患者における心不全予防のための骨格筋を標的とする戦略(Skeletal Muscle-targeted Strategy for Heart Failure Prevention in Elderly, Frail Patients after ST-elevation Myocardial Infarction)

小西正紹, 松澤泰志, 秋山英一, 木村裕一郎, 前島信彦, 岩橋徳明, 日比潔, 小菅雅美, 海老名俊明, 木村一雄, 田村功一

日本循環器学会学術集会抄録集 82回 PL8 - 6 2018.3

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aVR誘導のST部分上昇の消失がみられないことは非ST部分上昇型急性冠動脈症候群患者の1年有害転帰を予測する(No ST-Segment Elevation Resolution in Lead aVR Strongly Predicts 1-Year Adverse Outcomes in Patients with Non-ST-Segment Elevation Acute Coronary Syndrome)

小菅雅美, 日比潔, 岩橋徳明, 前島信彦, 松澤泰志, 小西正紹, 海老名俊明, 木村裕一郎, 田村功一, 木村一雄

日本循環器学会学術集会抄録集 82回 OJ16 - 1 2018.3

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aVR誘導のST部分下降は下壁急性心筋梗塞患者の30日有害転帰を予測する(ST-Segment Depression in Lead aVR Predicts 30-day Adverse Outcomes in Patients with Inferior Acute Myocardial Infarction)

小菅雅美, 日比潔, 岩橋徳明, 前島信彦, 松澤泰志, 小西正紹, 海老名俊明, 木村裕一郎, 田村功一, 木村一雄

日本循環器学会学術集会抄録集 82回 OJ16 - 2 2018.3

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急性期の血糖変動からSTEMI患者の左室リモデリングが予測可能である(Glycemic Variability at Acute Phase can Predict Left Ventricle Remodeling in Patients with STEMI)

高橋広軌, 岩橋徳明, 南本祐吾, 桐ヶ谷仁, 木村裕一郎, 松澤泰志, 小西正紹, 前島信彦, 日比潔, 小菅雅美, 海老名俊明, 田村功一, 木村一雄

日本循環器学会学術集会抄録集 82回 PJ002 - 6 2018.3

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Low Skeletal Muscle Mass Index is Associated With Cardiovascular Events in Patients After ST-Segment Elevation Myocardial Infarction

Ryosuke Satou, Yasushi Matsuzawa, Eiichi Akiyama, Chika Kawashima, Hiroyuki Suzuki, Masaaki Konishi, Nobuhiko Maejima, Noriaki Iwahashi, Kiyoshi Hibi, Masami Kosuge, Kazuo Kimura, Kouichi Tamura, Toshiaki Ebina

CIRCULATION 136 2017.11

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Clinical Significance of Control of Rapid Atrial Fibrillation by Landiolol in Patients With Heart Failure With Severely Reduced Ejection Fraction: The Role of Ultra-Short-Acting beta 1-Selective Blocker

Noriaki Iwahashi, Hironori Takahashi, Jin Kirigaya, Yugo Minamimoto, Yuichiro Kimura, Yasushi Matsuzawa, Masaaki Konishi, Nobuhiko Maejima, Kiyoshi Hibi, Masami Kosuge, Toshiaki Ebina, Kazuo Kimura, Kouichi Tamura

CIRCULATION 136 2017.11

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Endothelial Dysfunction is Associated With Cardiovascular Events in Male Patients After ST-Segment Elevation Myocardial Infarction

Ryosuke Satou, Yasushi Matsuzawa, Eiichi Akiyama, Chika Kawashima, Hiroyuki Suzuki, Masaaki Konishi, Nobuhiko Maejima, Noriaki Iwahashi, Kiyoshi Hibi, Masami Kosuge, Toshiaki Ebina, Kazuo Kimura, Kouichi Tamura

CIRCULATION 136 2017.11

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Prolonged Fever After ST-Segment Elevation Myocardial Infarction and Long-Term Cardiac Outcomes. Reviewed International journal

Chika Kawashima, Yasushi Matsuzawa, Eiichi Akiyama, Masaaki Konishi, Hiroyuki Suzuki, Katsutaka Hashiba, Toshiaki Ebina, Masami Kosuge, Kiyoshi Hibi, Kengo Tsukahara, Noriaki Iwahashi, Nobuhiko Maejima, Kentaro Sakamaki, Satoshi Umemura, Kazuo Kimura, Kouichi Tamura

Journal of the American Heart Association 6 ( 7 ) 2017.7

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DOI： 10.1161/JAHA.116.005463

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左前下行枝と非左前下行枝における機能的評価とOFDIの関係

松下絢介, 日比潔, 岡田興造, 木村裕一郎, 松澤泰志, 前島信彦, 岩橋徳明, 小菅雅美, 海老名俊明, ピーター・フィッツジェラルド, 本多康浩, 木村一雄

日本心血管インターベンション治療学会抄録集 26回 MO108 - MO108 2017.7

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高度石灰化病変に対するローターブレーター治療におけるPolishの効果について OCTによる検討

前島信彦, 日比潔, 川島千佳, 高橋広軌, 菊地進之介, 桐ヶ谷仁, 佐藤亮佑, 中橋秀文, 松下絢介, 南本祐吾, 松澤泰志, 小西正紹, 岩橋徳明, 小菅雅美, 海老名俊明, 木村一雄

日本心血管インターベンション治療学会抄録集 26回 MO263 - MO263 2017.7

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Physiology-guided PCI 生き残るのは、FFR?それともiFR?それともFFRCT? iFRとFFRの解剖学的狭窄度との関係

松下絢介, 日比潔, 岡田興造, 木村裕一郎, 松澤泰志, 前島信彦, 岩橋徳明, 小菅雅美, 海老名俊明, ピーター・フィッツジェラルド, 本多康浩, 木村一雄

日本心血管インターベンション治療学会抄録集 26回 RD25 - 1 2017.7

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急変時の対応、合併症への対処経カテーテル大動脈弁留置術直後に心タンポナーデを発症し、緊急開胸になった1例大動脈造影からいち早く合併症を予測する

塩入知子, 櫻田尚武, 井川健, 杉山昌弘, 森幸絵, 坂野智一, 石川栄二, 菊地達也, 日比潔, 輕部義久, 松下絢介, 南本祐吾, 笠間啓一郎, 岩橋徳明, 内田敬二, 益田宗孝, 木村一雄

日本心血管インターベンション治療学会抄録集 26回 CPD1 - 2 2017.7

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Primary PCIを受けたST部分上昇型心筋梗塞患者における灌流障害と血小板凝集の関係(Relationship between Reperfusion Injury and Platelet Aggregation in Patients with ST-segment Elevation Myocardial Infarction Undergoing Primary Percutaneous Coronary Intervention)

Ichikawa Shinya, Tsukahara Kengo, Kikuchi Shinnosuke, Kimura Yuichiro, Matsuzawa Yasushi, Maejima Nobuhiko, Iwahashi Noriaki, Hibi Kiyoshi, Kosuge Masami, Ebina Toshiaki, Kimura Kazuo, Tamura Koichi

日本循環器学会学術集会抄録集 81回 PE - 817 2017.3

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急性前壁STEMI患者においてOCTで評価したプラーク形態が受診時の心筋損傷に及ぼす影響(Impact of Plaque Morphology as Assessed by OCT on Myocardial Damage at Presentation in Patients with Acute Anterior STEMI)

Maejima Nobuhiko, Kosuge Masami, Hibi Kiyoshi, Kikuchi Shinnosuke, Kirigaya Jin, Takahashi Hironori, Kawashima Chika, Satou Ryosuke, Nakahashi Hidefumi, Ichikawa Shinya, Kuji Shotaro, Matsushita Kensuke, Minamimoto Yugo, Kimura Yuichiro, Matsuzawa Yasushi, Hashiba Katsutaka, Konishi Masaaki, Iwahashi Noriaki, Ebina Toshiaki, Kimura Kazuo, Tamura Koichi

日本循環器学会学術集会抄録集 81回 PE - 492 2017.3

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ST上昇型心筋梗塞患者の心血管事象に対する低体格指数の年齢依存的予測能(Age-dependent Prognostic Value of Low Body Mass Index for Cardiovascular Events in Patients with ST-segment Elevation Myocardial Infarction)

Matsuzawa Yasushi, Konishi Masaaki, Kawashima Chika, Satou Ryosuke, Akiyama Eiichi, Nakahashi Hidefumi, Ichikawa Shinya, Kikuchi Shinnosuke, Minamimoto Yugo, Maejima Nobuhiko, Iwahashi Noriaki, Kosuge Masami, Ebina Toshiaki, Kimura Kazuo

日本循環器学会学術集会抄録集 81回 OE - 303 2017.3

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ST上昇型心筋梗塞を伴う糖尿病患者における総血栓形成解析システムを用いた血小板反応性の評価(Assessment of Platelet Reactivity Using the Total Thrombus-formation Analysis System in Diabetics with ST-elevation Myocardial Infarction)

Kikuchi Shinnosuke, Tsukahara Kengo, Ichikawa Shinya, Kimura Yuichiro, Matsuzawa Yasushi, Maejima Nobuhiko, Iwahashi Noriaki, Hibi Kiyoshi, Kosuge Masami, Ebina Toshiaki, Kimura Kazuo, Tamura Koichi

日本循環器学会学術集会抄録集 81回 OE - 389 2017.3

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洞不全症候群、発作性心房細動に対してカテーテルアブレーションを施行したが、ペースメーカー植込みを回避できなかった1例

増田由茉, 木村裕一郎, 菊地進之介, 岩橋徳明, 日比潔, 海老名俊明, 小菅雅美, 木村一雄

日本内科学会関東地方会 630回 67 - 67 2017.2

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Combined impact of chronic kidney disease and contrast-induced nephropathy on long-term outcomes in patients with ST-segment elevation acute myocardial infarction who undergo primary percutaneous coronary intervention. Reviewed

Hidefumi Nakahashi, Masami Kosuge, Kentaro Sakamaki, Masayoshi Kiyokuni, Toshiaki Ebina, Kiyoshi Hibi, Kengo Tsukahara, Noriaki Iwahashi, Shotaro Kuji, Mari S Oba, Satoshi Umemura, Kazuo Kimura

Heart and vessels 32 ( 1 ) 22 - 29 2017.1

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DOI： 10.1007/s00380-016-0836-8

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Pharmacodynamic Assessment of Platelet Reactivity After a Loading Dose of Prasugrel or Clopidogrel in Patients With ST-Segment Elevation Myocardial Infarction. Reviewed

Shinya Ichikawa, Kengo Tsukahara, Yugo Minamimoto, Yuichiro Kimura, Yasushi Matsuzawa, Nobuhiko Maejima, Noriaki Iwahashi, Kiyoshi Hibi, Masami Kosuge, Toshiaki Ebina, Kazuo Kimura

Circulation journal : official journal of the Japanese Circulation Society 80 ( 12 ) 2520 - 2527 2016.11

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DOI： 10.1253/circj.CJ-16-0513

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Association between epicardial adipose tissue volume and myocardial salvage in patients with a first ST-segment elevation myocardial infarction: An epicardial adipose tissue paradox. Reviewed International journal

Masaomi Gohbara, Noriaki Iwahashi, Eiichi Akiyama, Nobuhiko Maejima, Kengo Tsukahara, Kiyoshi Hibi, Masami Kosuge, Toshiaki Ebina, Satoshi Umemura, Kazuo Kimura

Journal of cardiology 68 ( 5 ) 399 - 405 2016.11

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DOI： 10.1016/j.jjcc.2015.10.018

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The Combination of Dyssynchrony and Global Longitudinal Strain by 3D Speckle Tracking After ST-Elevation Myocardial Infarction is an Useful Predictor

Noriaki Iwahashi, Hironori Takahashi, Yasushi Matsuzawa, Nobuhiko Maejima, Kiyoshi Hibi, Masami Kosuge, Toshiaki Ebina, Kazuo Kimura

CIRCULATION 134 2016.11

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Impact of Change in Red Cell Distribution Width on Long-term Outcomes in Patients With Acute Myocardial Infarction Undergoing Primary Percutaneous Coronary Intervention

Hidefumi Nakahashi, Masami Kosuge, Masayoshi Kiyokuni, Toshiaki Ebina, Kiyoshi Hibi, Noriaki Iwahashi, Nobuhiko Maejima, Yasushi Matsuzawa, Yuichiro Kimura, Kazuo Kimura

CIRCULATION 134 2016.11

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Impact of Change in Red Cell Distribution Width on Long-term Outcomes in Patients With Acute Myocardial Infarction Undergoing Primary Percutaneous Coronary Intervention

Hidefumi Nakahashi, Masami Kosuge, Masayoshi Kiyokuni, Toshiaki Ebina, Kiyoshi Hibi, Noriaki Iwahashi, Nobuhiko Maejima, Yasushi Matsuzawa, Yuichiro Kimura, Kazuo Kimura

CIRCULATION 134 2016.11

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STEMI症例におけるインスリン抵抗性と梗塞サイズ・拡張能・リモデリングの比較

岩橋徳明, 片岡俊介, 南本祐吾, 松澤泰志, 前島信彦, 日比潔, 小菅雅美, 海老名俊明, 木村一雄

日本心臓病学会学術集会抄録 64回 P - 060 2016.9

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透析患者・非透析患者におけるiFR・FFR値の関係

松下絢介, 日比潔, 松澤泰志, 木村裕一郎, 前島信彦, 岩橋徳明, 小菅雅美, 海老名俊明, 梅村敏, 木村一雄

日本心臓病学会学術集会抄録 64回 P - 067 2016.9

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慢性心不全患者に対する還元型コエンザイムQ10投与の血管内皮機能改善効果

川島千佳, 松澤泰志, 秋山英一, 前島信彦, 岩橋徳明, 日比潔, 小菅雅美, 海老名俊明, 木村一雄

日本心臓病学会学術集会抄録 64回 P - 463 2016.9

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急性心筋梗塞後にHFpEFに陥る症例の特徴

岩橋徳明, 片岡俊介, 日比潔, 小菅雅美, 海老名俊明, 木村一雄, 前島信彦, 松澤泰志, 南本祐吾

日本心臓病学会学術集会抄録 64回 P - 551 2016.9

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急性心筋梗塞緊急冠動脈ステント留置例における造影剤腎症の重症度と3年予後との関係 Reviewed

中橋秀文, 小菅雅美, 清國雅義, 海老名俊明, 日比潔, 岩橋徳明, 前島信彦, 松澤泰志, 秋山英一, 木村裕一郎, 梅村敏, 木村一雄

日本心臓病学会学術集会抄録 64回 P - 051 2016.9

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多剤抗血栓薬服用患者におけるマイクロチップ型フローチャンバーシステムを用いた血栓形成能の定量的評価

市川晋也, 塚原健吾, 木村裕一郎, 松澤泰志, 前島信彦, 岩橋徳明, 日比潔, 小菅雅美, 海老名俊明, 木村一雄

日本心臓病学会学術集会抄録 64回 O - 205 2016.9

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ペースメーカー植込み後、徐脈依存性に心房刺激閾値上昇を認め、phase 4ブロックの関与が考えられた洞不全症候群の1例

木村裕一郎, 住田晋一, 前島信彦, 岩橋徳明, 日比潔, 海老名俊明, 石川利之, 木村一雄

日本心臓病学会学術集会抄録 64回 P - 042 2016.9

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FFR・iFRの乖離例の特徴

松下絢介, 日比潔, 木村裕一郎, 松澤泰志, 前島信彦, 岩橋徳明, 小菅雅美, 海老名俊明, 梅村敏, 木村一雄

日本心血管インターベンション治療学会抄録集 25回 MO148 - MO148 2016.7

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回転式アテレクトミーを施行する高度石灰化病変においてバルーン後に石灰化組織に生じた亀裂の臨床的意義について

前島信彦, 日比潔, 久慈正太郎, 南本祐吾, 松下絢介, 松澤泰志, 羽柴克孝, 岩橋徳明, 小菅雅美, 海老名俊明, 木村一雄

日本心血管インターベンション治療学会抄録集 25回 MO154 - MO154 2016.7

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Lesion Specific Strategy by Using Imaging Modality 中等度狭窄病変におけるFFR・iFRと冠動脈内イメージングの関係

松下絢介, 日比潔, 岡田興造, 木村裕一郎, 松澤泰志, 前島信彦, 岩橋徳明, 小菅雅美, 海老名俊明, 住田晋一, フィッツジェラルド・ピーター, 本多康浩, 梅村敏, 木村一雄

日本心血管インターベンション治療学会抄録集 25回 PD04 - 1 2016.7

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Effects of 4 Statins on Regression of Coronary Plaque in Acute Coronary Syndrome. Reviewed

Kensuke Matsushita, Kiyoshi Hibi, Naohiro Komura, Eiichi Akiyama, Nobuhiko Maejima, Noriaki Iwahashi, Kengo Tsukahara, Masami Kosuge, Toshiaki Ebina, Shinichi Sumita, Satoshi Umemura, Kazuo Kimura

Circulation journal : official journal of the Japanese Circulation Society 80 ( 7 ) 1634 - 43 2016.6

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DOI： 10.1253/circj.CJ-15-1379

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Symptomatic radiation-induced cardiac disease in long-term survivors of esophageal cancer. Reviewed International journal

Ichiro Ogino, Shigenobu Watanabe, Noriaki Iwahashi, Masami Kosuge, Kentaro Sakamaki, Chikara Kunisaki, Kazuo Kimura

Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al] 192 ( 6 ) 359 - 67 2016.6

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DOI： 10.1007/s00066-016-0956-1

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Clinical Impact of the Cardio-Ankle Vascular Index for Predicting Cardiovascular Events After Acute Coronary Syndrome. Reviewed

Masaomi Gohbara, Noriaki Iwahashi, Yuka Sano, Eiichi Akiyama, Nobuhiko Maejima, Kengo Tsukahara, Kiyoshi Hibi, Masami Kosuge, Toshiaki Ebina, Satoshi Umemura, Kazuo Kimura

Circulation journal : official journal of the Japanese Circulation Society 80 ( 6 ) 1420 - 6 2016.5

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DOI： 10.1253/circj.CJ-15-1257

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Relationship Between Thickness of Calcium on Optical Coherence Tomography and Crack Formation After Balloon Dilatation in Calcified Plaque Requiring Rotational Atherectomy. Reviewed

Nobuhiko Maejima, Kiyoshi Hibi, Kenichiro Saka, Eiichi Akiyama, Masaaki Konishi, Mitsuaki Endo, Noriaki Iwahashi, Kengo Tsukahara, Masami Kosuge, Toshiaki Ebina, Satoshi Umemura, Kazuo Kimura

Circulation journal : official journal of the Japanese Circulation Society 80 ( 6 ) 1413 - 9 2016.5

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DOI： 10.1253/circj.CJ-15-1059

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急性心筋梗塞後の長期転帰に対する赤血球分布幅の予後的価値(Predictive Value of Red Cell Distribution Width for Long-term Outcomes after Acute Myocardial Infarction) Reviewed

Nakahashi Hidefumi, Kosuge Masami, Kiyokuni Masayoshi, Ebina Toshiaki, Hibi Kiyoshi, Tsukahara Kengo, Iwahashi Noriaki, Maejima Nobuhiko, Akiyama Eiichi, Umemura Satoshi, Kimura Kazuo

Circulation Journal 80 ( Suppl.I ) 2946 - 2946 2016.3

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慢性腎臓病と造影剤腎症が急性心筋梗塞患者の長期転帰に及ぼす複合的影響(Combined Impact of Chronic Kidney Disease and Contrast-Induced Nephropathy on Long-term Outcomes in Patients with Acute Myocardial Infarction) Reviewed

Nakahashi Hidefumi, Kosuge Masami, Kiyokuni Masayoshi, Ebina Toshiaki, Hibi Kiyoshi, Tsukahara Kengo, Iwahashi Noriaki, Maejima Nobuhiko, Akiyama Eiichi, Umemura Satoshi, Kimura Kazuo

Circulation Journal 80 ( Suppl.I ) 2859 - 2859 2016.3

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急性心筋梗塞患者において慢性腎疾患と貧血が長期転帰に及ぼす複合的影響(Combined Impact of Chronic Kidney Disease and Anemia on Long-term Outcomes in Patients with Acute Myocardial Infarction) Reviewed

Nakahashi Hidefumi, Kosuge Masami, Kiyokuni Masayoshi, Ebina Toshiaki, Hibi Kiyoshi, Tsukahara Kengo, Iwahashi Noriaki, Maejima Nobuhiko, Akiyama Eiichi, Umemura Satoshi, Kimura Kazuo

Circulation Journal 80 ( Suppl.I ) 2935 - 2935 2016.3

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Simultaneous fat and bone assessment in hospitalized heart failure patients using non-contrast-enhanced computed tomography. Reviewed International journal

Masaaki Konishi, Eiichi Akiyama, Hiroyuki Suzuki, Noriaki Iwahashi, Nobuhiko Maejima, Kengo Tsukahara, Kiyoshi Hibi, Masami Kosuge, Toshiaki Ebina, Yasushi Matsuzawa, Satoshi Umemura, Kazuo Kimura

Journal of cardiology 67 ( 1 ) 92 - 7 2016.1

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DOI： 10.1016/j.jjcc.2015.03.016

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Glycemic Variability on Continuous Glucose Monitoring System Correlates With Non-Culprit Vessel Coronary Plaque Vulnerability in Patients With First-Episode Acute Coronary Syndrome - Optical Coherence Tomography Study. Reviewed

Masaomi Gohbara, Kiyoshi Hibi, Takayuki Mitsuhashi, Nobuhiko Maejima, Noriaki Iwahashi, Shunsuke Kataoka, Eiichi Akiyama, Kengo Tsukahara, Masami Kosuge, Toshiaki Ebina, Satoshi Umemura, Kazuo Kimura

Circulation journal : official journal of the Japanese Circulation Society 80 ( 1 ) 202 - 10 2016

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DOI： 10.1253/circj.CJ-15-0790

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Plasma Glucagon-Like Peptide-1 and Tissue Characteristics of Coronary Plaque in Non-Diabetic Acute Coronary Syndrome Patients. Reviewed

Takayuki Mitsuhashi, Kiyoshi Hibi, Masaaki Konishi, Nobuhiko Maejima, Noriaki Iwahashi, Kengo Tsukahara, Masami Kosuge, Toshiaki Ebina, Satoshi Umemura, Kazuo Kimura

Circulation journal : official journal of the Japanese Circulation Society 80 ( 2 ) 469 - 76 2016

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DOI： 10.1253/circj.CJ-15-0718

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Urgent Control of Rapid Atrial Tachyarrhythmia Using Landiolol in Patients With Heart Failure With Severely Reduced Ejection Fraction : An Ultra-Short-Acting beta-blocker for Emergency ADHF

Noriaki Iwahashi, Masaomi Gohbara, Shunsuke Kataoka, Yugo Minamimoto, Eiichi Akiyama, Nobuhiko Maejima, Kengo Tsukahara, Kiyoshi Hibi, Masami Kosuge, Masami Kosuge, Toshiaki Ebina, Satoshi Umemura, Kazuo Kimura

CIRCULATION 132 2015.11

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Characteristics of Patients with HFpEF Followed up after a Reperfused First STEMI: The Risk/Benefit of the Administration of Diuretics

Noriaki Iwahashi, Toshiaki Ebina, Satoshi Umemura, Kazuo Kimura

JOURNAL OF CARDIAC FAILURE 21 ( 10 ) S156 - S156 2015.10

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DOI： 10.1016/j.cardfail.2015.08.062

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The Control of Rapid Atrial Tachyarrhythmia in Patients with Heart Failure with Severely Reduced Ejection Fraction: Usefulness of Landiolol

Noriaki Iwahashi, Toshiaki Ebina, Satoshi Umemura, Kazuo Kimura

JOURNAL OF CARDIAC FAILURE 21 ( 10 ) S153 - S153 2015.10

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DOI： 10.1016/j.cardfail.2015.08.045

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急性心筋梗塞緊急冠インターベンション施行例における慢性腎臓病と造影剤腎症が院内予後に及ぼす影響 Reviewed

中橋秀文, 小菅雅美, 清國雅義, 海老名俊明, 日比潔, 塚原健吾, 岩橋徳明, 前島信彦, 羽柴克孝, 秋山英一, 梅村敏, 木村一雄

日本心臓病学会学術集会抄録 63回 891 - 891 2015.9

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回転式アテレクトミーを必要とする高度石灰化病変におけるOCTガイドPCIの有用性

前島信彦, 日比潔, 久慈正太郎, 南本祐吾, 秋山英一, 松澤泰志, 岩橋徳明, 塚原健吾, 小菅雅美, 海老名俊明, 梅村敏, 木村一雄

日本心臓病学会学術集会抄録 63回 273 - 273 2015.9

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AMIにおける3Dスペックルトラッキングを用いて算出されるglobal circumferential strainの役割に関する検討

岩橋徳明, 郷原正臣, 片岡俊介, 秋山英一, 前島信彦, 塚原健吾, 日比潔, 小菅雅美, 海老名俊明, 梅村敏, 木村一雄

日本心臓病学会学術集会抄録 63回 790 - 790 2015.9

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マイクロフローチャンバーシステムを用いた抗血栓薬の定量的評価

市川晋也, 塚原健吾, 秋山英一, 岩橋徳明, 前島信彦, 日比潔, 小菅雅美, 海老名俊明, 梅村敏, 木村一雄

日本心臓病学会学術集会抄録 63回 953 - 953 2015.9

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一時的下大静脈フィルターが留置された急性静脈血栓塞栓症におけるフィルター内血栓

塚原健吾, 羽柴克孝, 海老名俊明, 日比潔, 岩橋徳明, 前島信彦, 秋山英一, 木村一雄, 梅村敏

日本心臓病学会学術集会抄録 63回 962 - 962 2015.9

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心疾患患者における糖尿病の管理急性冠症候群の血糖変動の意義

郷原正臣, 岩橋徳明, 片岡俊介, 秋山英一, 前島信彦, 塚原健吾, 日比潔, 小菅雅美, 海老名俊明, 梅村敏, 木村一雄

日本心臓病学会学術集会抄録 63回 1074 - 1074 2015.9

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初回ST上昇型急性心筋梗塞におけるQRS時間と梗塞サイズの関係

岩橋徳明, 郷原正臣, 片岡俊介, 秋山英一, 前島信彦, 塚原健吾, 日比潔, 小菅雅美, 海老名俊明, 梅村敏, 木村一雄

日本心臓病学会学術集会抄録 63回 1106 - 1106 2015.9

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IVUS・OFDIによる計測値の比較検討

松下絢介, 日比潔, 岡田興造, 秋山英一, 前島信彦, 岩橋徳明, 塚原健吾, 小菅雅美, 海老名俊明, フィッツジェラルド・ピーター, 本多康浩, 梅村敏, 木村一雄

日本心臓病学会学術集会抄録 63回 1208 - 1208 2015.9

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GLOBAL LONGITUDINAL STRAIN BY 3D SPECKLE TRACKING AFTER ST-ELEVATION MYOCARDIAL INFARCTION IS USEFUL FOR PREDICTING LEFT VENTRICULAR REMODELING: COMPARISON WITH TC99M-SESTAMIBI

Noriaki Iwahashi, Masaomi Gohbara, Shunsuke Kataoka, Eiichi Akiyama, Nobuhiko Maejima, Kengo Tsukahara, Kiyoshi Hibi, Masami Kosuge, Toshiaki Ebina, Satoshi Umemura, Kazuo Kimura

JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY 65 ( 10 ) A1228 - A1228 2015.3

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DOI： 10.1016/S0735-1097(15)61228-1

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ESTIMATION OF ACUTE ONSET GLOBAL LONGITUDINAL STRAIN BY 3D SPECKLE TRACKING AFTER ST-ELEVATION MYOCARDIAL INFARCTION IS USEFUL FOR PREDICTION OF FINAL INFARCT SIZE AND LEFT VENTRICULAR REMODELING

Noriaki Iwahashi, Masaomi Gohbara, Eiichi Akiyama, Shunsuke Kataoka, Nobuhiko Maejima, Kengo Tsukahara, Kiyoshi Hibi, Masami Kosuge, Toshiaki Ebina, Satoshi Umemura, Kazuo Kimura

JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY 65 ( 10 ) A1212 - A1212 2015.3

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DOI： 10.1016/S0735-1097(15)61212-8

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THE COMBINATION OF DYSSYNCHRONY AND GLOBAL LONGITUDINAL STRAIN BY 3D SPECKLE TRACKING AFTER ST-ELEVATION MYOCARDIAL INFARCTION IS USEFUL FOR PREDICTION OF FINAL INFARCT SIZE AND LEFT VENTRICULAR REMODELING

Noriaki Iwahashi, Masaomi Gohbara, Shunsuke Kataoka, Eiichi Akiyama, Nobuhiko Maejima, Kengo Tsukahara, Kiyoshi Hibi, Masami Kosuge, Toshiaki Ebina, Satoshi Umemura, Kazuo Kimura

JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY 65 ( 10 ) A192 - A192 2015.3

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DOI： 10.1016/S0735-1097(15)60192-9

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Hypercapnia in patients with acute heart failure. Reviewed International journal

Masaaki Konishi, Eiichi Akiyama, Hiroyuki Suzuki, Noriaki Iwahashi, Nobuhiko Maejima, Kengo Tsukahara, Kiyoshi Hibi, Masami Kosuge, Toshiaki Ebina, Kentaro Sakamaki, Yasushi Matsuzawa, Mitsuaki Endo, Satoshi Umemura, Kazuo Kimura

ESC heart failure 2 ( 1 ) 12 - 19 2015.3

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DOI： 10.1002/ehf2.12023

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Right Ventricular Dysfunction Plays an Important Role in Predicting Non-Response to Tolvaptan Treatment in Patients With Heart Failure With Reduced Ejection Fraction With Chronic Kidney Disease

Noriaki Iwahashi, Masaomi Gohbara, Shunsuke Kataoka, Eiichi Akiyama, Nobuhiko Maejima, Kengo Tsukahara, Kiyoshi Hibi, Masami Kosuge, Toshiaki Ebina, Satoshi Umemura, Kazuo Kimura

CIRCULATION 130 2014.11

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The Combination of Dyssynchrony and Global Longitudinal Strain by 3D Speckle Tracking After ST-Elevation Myocardial Infarction is Useful for Prediction of Final Infarct Size and Left Ventricular Remodeling

Noriaki Iwahashi, Masaomi Gohbara, Shunsuke Kataoka, Eiichi Akiyama, Nobuhiko Maejima, Kengo Tsukahara, Kiyoshi Hibi, Masami Kosuge, Toshiaki Ebina, Satoshi Umemura, Kazuo Kimura

CIRCULATION 130 2014.11

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Estimation of Acute Onset Global Longitudinal Strain by 3D Speckle Tracking After ST -Elevation Myocardial Infarction is Useful for Predicting Left Ventricular Remodeling

Noriaki Iwahashi, Masaomi Gohbara, Eiichi Akiyama, Nobuhiko Maejima, Kengo Tsukahara, Kiyoshi Hibi, Masami Kosuge, Toshiaki Ebina, Satoshi Umemura, Kazuo Kimura

CIRCULATION 130 2014.11

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Impact of Insulin Resistance on Left Ventricular Remodeling in Patients With a First-Time ST Elevation Acute Myocardial Infarction Without Overt Diabetes Mellitus

Noriaki Iwahashi, Masaomi Gohbara, Shunsuke Kataoka, Eiichi Akiyama, Nobuhiko Maejima, KEngo Tsukahara, Kiyoshi Hibi, Masami Kosuge, Toshiaki Ebina, Satoshi Umemura, Kazuo Kimura

CIRCULATION 130 2014.11

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RV Dysfunction Plays an Important Role in Predicting Non-response to Tolvaptan in Patients with Heart Failure with Reduced Ejection Fraction

Noriaki Iwahashi, Toshiaki Ebina, Kazuo Kimura

JOURNAL OF CARDIAC FAILURE 20 ( 10 ) S174 - S175 2014.10

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DOI： 10.1016/j.cardfail.2014.07.245

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Evaluating the Morphological and Hemodynamic Status in Patients with Ischemic Heart Failure Using Several Imaging Modalities

Noriaki Iwahashi, Toshiaki Ebina, Kazuo Kimura

JOURNAL OF CARDIAC FAILURE 20 ( 10 ) S136 - S136 2014.10

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DOI： 10.1016/j.cardfail.2014.07.021

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Intensive And Moderate Lipid Lowering Therapy To Prevent Progression Of Coronary Atherosclerosis In Patients With Acute Coronary Syndrome Reviewed

Matsushita Kensuke, Hibi Kiyoshi, Kuji Shotaro, Suzuki Hiroyuki, Gohbara Masaomi, Nakayama Naoki, Takano Keiko, Maejima Nobuhiko, Iwahashi Noriaki, Tsukahara Kengo, Kosuge Masami, Ebina Toshiaki, Umemura Satoshi, Kimura Kazuo

JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY 64 ( 11 ) B101 - B101 2014.9

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DOI： 10.1016/j.jacc.2014.07.396

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下肢末梢動脈疾患の血管内イメージングより冠動脈疾患を予測できるか?

南本祐吾, 日比潔, 塚原健吾, 海老名俊明, 小菅雅美, 岩橋徳明, 前島信彦, 秋山英一, 高野桂子, 中山尚貴, 郷原正臣, 片岡俊介, 鈴木弘之, 松下絢介, 木村一雄, 梅村敏

日本心臓病学会学術集会抄録 62回 P - 482 2014.9

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非ST上昇型急性冠症候群におけるSYNTAXスコアと責任血管のプラーク形態との関係 OCTを用いた検討

坂賢一郎, 日比潔, 奥田純, 前島信彦, 岩橋徳明, 塚原健吾, 小菅正美, 海老名俊明, 梅村敏, 木村一雄

日本内分泌学会雑誌 90 ( 2 ) 753 - 753 2014.9

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急性冠症候群患者における夜間血圧変動と左室肥大や頸動脈硬化との関連の検討

片岡俊介, 秋山英一, 前島信彦, 岩橋徳明, 塚原健吾, 日比潔, 小菅雅美, 海老名俊明, 梅村敏, 木村一雄

日本内分泌学会雑誌 90 ( 2 ) 759 - 759 2014.9

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持続血糖測定器CGMSで評価した血糖変動はST上昇型急性心筋梗塞患者の左室リモデリングの予測因子である

郷原正臣, 岩橋徳明, 秋山英一, 前島信彦, 塚原健吾, 日比潔, 小菅雅美, 海老名俊明, 梅村敏, 木村一雄

日本内分泌学会雑誌 90 ( 2 ) 761 - 761 2014.9

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前胸部誘導で陰性T波を認める左前下行枝病変の急性冠症候群、急性肺塞栓、たこつぼ型心筋症の心電図学的鑑別

小菅雅美, 海老名俊明, 日比潔, 塚原健吾, 岩橋徳明, 前島信彦, 秋山英一, 梅村敏, 木村一雄

日本心臓病学会学術集会抄録 62回 O - 129 2014.9

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3次元ストレインを用いたGlobal longitudinal Strainは初回ST上昇が急性心筋梗塞のリモデリング予測に有用である

岩橋徳明, 郷原正臣, 前島信彦, 塚原健吾, 日比潔, 小菅雅美, 海老名俊明, 石川利之, 梅村敏, 木村一雄

日本心臓病学会学術集会抄録 62回 P - 037 2014.9

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冠攣縮性狭心症による心肺停止蘇生例の特徴と予後

中山尚貴, 秋山英一, 前島信彦, 岩橋徳明, 塚原健吾, 日比潔, 海老名俊明, 住田晋一, 木村一雄, 梅村敏

日本心臓病学会学術集会抄録 62回 P - 328 2014.9

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インスリン抵抗性は初回ST上昇型急性心筋梗塞における左室リモデリングの規定因子である

岩橋徳明, 郷原正臣, 前島信彦, 塚原健吾, 日比潔, 小菅雅美, 海老名俊明, 石川利之, 梅村敏, 木村一雄

日本心臓病学会学術集会抄録 62回 O - 490 2014.9

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急性前壁梗塞再灌流例で若年男性の肥満患者は院内予後が不良である

小菅雅美, 海老名俊明, 日比潔, 塚原健吾, 岩橋徳明, 前島信彦, 秋山英一, 梅村敏, 木村一雄

日本心臓病学会学術集会抄録 62回 O - 501 2014.9

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急性冠症候群患者に対するストロングスタチンとスタンダードスタチンのプラーク退縮率の比較

松下絢介, 日比潔, 前島信彦, 岩橋徳明, 塚原健吾, 小菅雅美, 海老名俊明, 住田晋一, 梅村敏, 木村一雄

日本内分泌学会雑誌 90 ( 2 ) 747 - 747 2014.9

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CLINICAL SIGNIFICANCE OF TWISTING MOTION ESTIMATED BY 3D SPECKLE TRACKING STRAIN ACUTELY AFTER ONSET OF ST-ELEVATION MYOCARDIAL INFARCTION

Noriaki Iwahashi, Masaomi Gohbara, Masaaki Konishi, Kengo Tsukahara, Yoshio Tahara, Kiyoshi Hibi, Masami Kosuge, Toshiaki Ebina, Satoshi Umemura, Kazuo Kimura

JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY 63 ( 12 ) A175 - A175 2014.4

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DOI： 10.1016/S0735-1097(14)60175-3

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一時的下大静脈フィルターを留置した静脈血栓塞栓症におけるアルガトロバンの有用性

塚原健吾, 海老名俊明, 小菅雅美, 日比潔, 岩橋徳明, 前島信彦, 小西正紹, 木村一雄

日本血栓止血学会誌 25 ( 2 ) 268 - 268 2014.4

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Higher level at admission and subsequent decline in hemoglobin in patients with acute pulmonary edema. Reviewed

Masaaki Konishi, Yasushi Matsuzawa, Hiroyuki Suzuki, Eiichi Akiyama, Noriaki Iwahashi, Nobuhiko Maejima, Mitsuaki Endo, Kengo Tsukahara, Kiyoshi Hibi, Masami Kosuge, Toshiaki Ebina, Kentaro Sakamaki, Satoshi Morita, Satoshi Umemura, Kazuo Kimura

Circulation journal : official journal of the Japanese Circulation Society 78 ( 4 ) 896 - 902 2014

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DOI： 10.1253/circj.CJ-13-1163

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急性冠症候群患者に対するストロングスタチンとスタンダードスタチンのプラーク退縮率の比較

松下絢介, 日比潔, 高野桂子, 秋山英一, 小西正昭, 前島信彦, 岩橋徳明, 塚原健吾, 田原良雄, 小菅雅美, 海老名俊明, 木村一雄

日本冠疾患学会雑誌 19 ( Suppl. ) 184 - 184 2013.12

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Relation Between Echocardiograms After Return of Spontaneous Circulation and Neurologic Outcomes in Patients Treated With Hypothermia After Out-of-hospital Ventricular Fibrillation Cardiac Arrest: J-PULSE-Hypo Registry

Yoshio Tahara, Kazuo Kimura, Noriaki Iwahashi, Naoto Morimura, Ken Nagao, Naohiro Yonemoto, Hiroyuki Yokoyama, Hiroshi Nonogi

CIRCULATION 128 ( 22 ) 2013.11

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The Relationship Between the Volume of Epicardial Adipose Tissue and the Infarct Size in Patients With a First STEMI: Cardiac MRI Study

Masaomi Gohbara, Noriaki Iwahashi, Masaaki Konishi, Nobuhiko Maejima, Kengo Tsukahara, Yoshio Tahara, Kiyoshi Hibi, Masami Kosuge, Toshiaki Ebina, Satoshi Umemura, Kazuo Kimura

CIRCULATION 128 ( 22 ) 2013.11

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Glycemic Variability Determined by a Continuous Glucose Monitoring System Predicts the Extent of the Peri-Infarct Zone and Left Ventricular Remodeling in Patients With a First-Time ST-Segment Elevation Myocardial Infarction.: Cardiac MRI study

Masaomi Gohbara, Noriaki Iwahashi, Shunsuke Kataoka, Kozo Okada, Masaaki Konishi, Nobuhiko Maejima, Kengo Tsukahara, Yoshio Tahara, Kiyoshi Hibi, Masami Kosuge, Toshiaki Ebina, Satoshi Umemura, Kazuo Kimura

CIRCULATION 128 ( 22 ) 2013.11

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Early Hemoglobin Decrease in Heart Failure With Acute Pulmonary Edema

Masaaki Konishi, Yasushi Matsuzawa, Hiroyuki Suzuki, Eiichi Akiyama, Noriaki Iwahashi, Kiyoshi Hibi, Masami Kosuge, Toshiaki Ebina, Kentaro Sakamaki, Satoshi Morita, Satoshi Umemura, Kazuo Kimura

CIRCULATION 128 ( 22 ) 2013.11

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Impact of Central Obesity on Long-term Cardiovascular Events in Younger Patients With ST-Elevation Myocardial Infarction

Keiko Takano, Kiyoshi Hibi, Masaaki Konishi, Nobuhiko Maeiima, Noriaki Iwahashi, Kengo Tsukahara, Masami Kosuge, Toshiaki Ebina, Kazuo Kimura, Satoshi Umemura

CIRCULATION 128 ( 22 ) 2013.11

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Clinical Usefulness of Twisting Motion Estimated by D-3 Speckle Tracking Strain Acutely After Onset of ST-Elevation Myocardial Infarction

Noriaki Iwahashi, Masaomi Gohbara, Masaaki Konishi, Nobuhiko Majima, Kengo Tsukahara, Yoshio Tahara, Kiyoshi Hibi, Masami Kosuge, Toshiaki Ebina, Toshiyuki Ishikawa, Satoshi Umemura, Kazuo Kimura

CIRCULATION 128 ( 22 ) 2013.11

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Right Ventricular Dysfunction Plays an Important Role in Predicting Non-Response to Tolvaptan Treatment in Patients With Heart Failure With Reduced Ejection Fraction: Strain Echocardiography Study

Noriaki Iwahashi, Masaomi Gohbara, Masaaki Konishi, Nobuhiko Maejima, Kengo Tsukahara, Yoshio Tahara, Kiyoshi Hibi, Masami Kosuge, Toshiaki Ebina, Toshiyuki Ishikawa, Satoshi Umemura, Kazuo Kimura

CIRCULATION 128 ( 22 ) 2013.11

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Global Longitudinal Strain Estimated by 3D Speckle Tracking Acutely After Onset of ST-Elevation Myocardial Infarction is Useful to Predict Final Infarct Size and Left Ventricular Remodeling

Noriaki Iwahashi, Masaomi Gohbara, Masaaki Konishi, Nobuhiko Maejima, Kengo Tsukahara, Yoshio Tahara, Kiyoshi Hibi, Masami Kosuge, Toshiaki Ebina, Toshiyuki Ishikawa, Satoshi Umemura, Kazuo Kimura

CIRCULATION 128 ( 22 ) 2013.11

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回転式アテレクトミーを必要とする高度石灰化病変において光干渉断層法(OCT)はバルーン拡張後の石灰化組織の亀裂を予想できるか?

前島信彦, 日比潔, 中山尚貴, 高野桂子, 秋山英一, 小西正紹, 岩橋徳明, 塚原健吾, 田原良雄, 小菅雅美, 海老名俊明, 梅村敏, 木村一雄

日本心臓病学会誌 8 ( Suppl.I ) 295 - 295 2013.9

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心不全患者に対するTolvaptan投与に関する患者背景や投与期間による有効性や予後に関する後ろ向き検討

岩橋徳明, 郷原正臣, 前島信彦, 塚原健吾, 田原良雄, 日比潔, 小菅雅美, 海老名俊明, 石川利之, 梅村敏, 木村一雄

日本心臓病学会誌 8 ( Suppl.I ) 300 - 300 2013.9

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急性下壁梗塞におけるV5-6誘導のST上昇と再灌流後の微小循環障害との関係

小菅雅美, 海老名俊明, 日比潔, 塚原健吾, 前島信彦, 田原良雄, 岩橋徳明, 郷原正臣, 永嶋善幸, 小西正紹, 梅村敏, 木村一雄

日本心臓病学会誌 8 ( Suppl.I ) 313 - 313 2013.9

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急性前壁梗塞で若年男性の肥満患者では再灌流後に微小循環障害を高率に認める

小菅雅美, 海老名俊明, 日比潔, 塚原健吾, 田原良雄, 前島信彦, 永嶋善幸, 郷原正臣, 岩橋徳明, 小西正紹, 梅村敏, 木村一雄

日本心臓病学会誌 8 ( Suppl.I ) 313 - 313 2013.9

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初回ST上昇型心筋梗塞におけるPeri-Infarct Zoneの検討心臓MRIにおける研究

郷原正臣, 岩橋徳明, 小西正紹, 前島信彦, 塚原健吾, 田原良雄, 日比潔, 小菅雅美, 海老名俊明, 梅村敏, 木村一雄

日本心臓病学会誌 8 ( Suppl.I ) 331 - 331 2013.9

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非ST上昇型急性冠症候群の臨床像

田原良雄, 木村一雄, 小菅雅美, 海老名俊明, 日比潔, 塚原健吾, 岩橋徳明, 前島信彦, 小西正紹, 秋山英一, 高野桂子, 郷原正臣, 永嶋善幸, 鈴木弘之, 片岡俊介, 梅村敏

日本心臓病学会誌 8 ( Suppl.I ) 345 - 345 2013.9

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整形外科術後の深部静脈血栓症の発症予測にRH-PATを使用した血管内皮機能検査が有効である

鈴木弘之, 松澤泰志, 小西正紹, 秋山英一, 海老名俊明, 日比潔, 小菅雅美, 塚原健吾, 岩橋徳明, 前島信彦, 岡田興造, 郷原正臣, 永嶋善幸, 梅村敏, 木村一雄

日本心臓病学会誌 8 ( Suppl.I ) 387 - 387 2013.9

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3次元スペックルトラッキングによる左室ねじれ運動の評価は初回ST上昇型急性心筋梗塞の梗塞サイズとリモデリング予測に有用である

岩橋徳明, 郷原正臣, 前島信彦, 塚原健吾, 田原良雄, 日比潔, 小菅雅美, 海老名俊明, 石川利之, 梅村敏, 木村一雄

日本心臓病学会誌 8 ( Suppl.I ) 477 - 477 2013.9

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心不全患者に対するTolvaptan投与の体重減少に関与する因子および予後への影響

岩橋徳明, 郷原正臣, 前島信彦, 塚原健吾, 田原良雄, 日比潔, 小菅雅美, 海老名俊明, 石川利之, 梅村敏, 木村一雄

日本心臓病学会誌 8 ( Suppl.I ) 549 - 549 2013.9

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若年ST上昇型心筋梗塞患者における中心性肥満が心血管イベントに与える影響について

高野桂子, 日比潔, 小西正紹, 前島信彦, 岩橋徳明, 塚原健吾, 田原良雄, 小菅雅美, 海老名俊明, 木村一雄

脈管学 53 ( Suppl. ) S193 - S193 2013.9

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入院直後および入院期間中のヘモグロビン値低下は急性心不全プロファイルを反映する

小西正紹, 鈴木弘之, 永嶋善幸, 郷原正臣, 松澤泰志, 前島信彦, 岩橋徳明, 塚原健吾, 日比潔, 田原良雄, 海老名俊明, 梅村敏, 木村一雄

日本心臓病学会誌 8 ( Suppl.I ) 555 - 555 2013.9

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初回STEMI患者における梗塞サイズとEpicardial Adipose Tissueの関係心臓MRIによる研究

郷原正臣, 岩橋徳明, 小西正紹, 前島信彦, 塚原健吾, 田原良雄, 日比潔, 小菅雅美, 海老名俊明, 梅村敏, 木村一雄

日本心臓病学会誌 8 ( Suppl.I ) 586 - 586 2013.9

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冠動脈穿孔症例の冠動脈造影(CAG)・血管内超音波(IVUS)上の特徴

松下絢介, 日比潔, 永嶋善幸, 郷原正臣, 中山尚貴, 高野桂子, 秋山英一, 小西正紹, 前島信彦, 岩橋徳明, 塚原健吾, 田原良雄, 小菅雅美, 海老名俊明, 梅村敏, 木村一雄

日本心臓病学会誌 8 ( Suppl.I ) 603 - 603 2013.9

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器質性および冠攣縮性狭心症の合併から心肺停止に至った一例

秋山英一, 鈴木弘之, 松澤泰志, 岡田興造, 小西正紹, 坂賢一郎, 遠藤光明, 前島信彦, 岩橋徳明, 田原良雄, 塚原健吾, 日比潔, 小菅雅美, 海老名俊明, 梅村敏, 木村一雄

日本心臓病学会誌 8 ( Suppl.I ) 648 - 648 2013.9

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整形外科術後の深部静脈血栓症の発症予測にRH-PATを使用した血管内皮機能検査が有効である

鈴木弘之, 松澤泰志, 小西正紹, 秋山英一, 高野桂子, 中山尚貴, 片岡俊介, 海老名俊明, 小菅雅美, 日比潔, 塚原健吾, 岩橋徳明, 前島信彦, 梅村敏, 木村一雄

脈管学 53 ( Suppl. ) S127 - S127 2013.9

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Polyvascular diseseを有する冠動脈インターベンション施行例の予後

塚原健吾, 木村一雄, 海老名俊明, 小菅雅美, 日比潔, 田原良雄, 岩橋徳明, 前島信彦, 小西正紹, 梅村敏

日本心臓病学会誌 8 ( Suppl.I ) 348 - 348 2013.9

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急変冠症候群患者における、夜間血圧変動と左室肥大や頸動脈硬化との関連の検討

片岡俊介, 岡田興造, 郷原正臣, 永嶋善幸, 秋山英一, 松澤泰志, 小西正紹, 前島信彦, 岩橋徳明, 塚原健吾, 田原良雄, 日比潔, 小菅雅美, 海老名俊明, 梅村敏, 木村一雄

日本心臓病学会誌 8 ( Suppl.I ) 381 - 381 2013.9

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CLINICAL USEFULNESS OF 3D SPECKLE TRACKING STRAIN ACUTELY ONSET AFTER STEMI

Noriaki Iwahashi, Masaomi Gohbara, Kozo Okada, Nobuhiko Maejima, Mitsuaki Endo, Kengo Tsukahara, Yoshio Tahara, Kiyoshi Hibi, Masami Kosuge, Toshiaki Ebina, Satoshi Umemura, Kazuo Kimura

JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY 61 ( 10 ) E1102 - E1102 2013.3

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DOI： 10.1016/S0735-1097(13)61102-X

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TWISTING MOTION ESTIMATED BY 3D SPECKLE-TRACKING STRAIN ACUTELY ONSET AFTER STEMI PREDICTS INFARCT SIZE AND LV REMODELING

Noriaki Iwahashi, Masaomi Gohbara, Kozo Okada, Nobuhiko Maejima, Mitsuaki Endo, Kengo Tsukahara, Yoshio Tahara, Kiyoshi Hibi, Masami Kosuge, Toshiaki Ebina, Satoshi Umemura, Kazuo Kimura

JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY 61 ( 10 ) E908 - E908 2013.3

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DOI： 10.1016/S0735-1097(13)60908-0

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MONOCYTOSIS AFTER MYOCARDIAL INFARCTION ACCELERATES ATHEROSCLEROSIS: RESULTS OF A FIVE-YEAR FOLLOW-UP STUDY

Keiko Takano, Kiyoshi Hibi, Masaaki Konishi, Yasushi Matsuzawa, Toshiaki Ebina, Masami Kosuge, Yoshio Tahara, Kengo Tsukahara, Mitsuaki Endo, Noriaki Iwahashi, Nobuhiko Maejima, Kenichirou Saka, Kozo Okada, Eiichi Akiyama, Masaomi Gobara, Zenkou Nagashima, Hiroyuki Suzuki, Kazuo Kimura, Satoshi Umemura

JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY 61 ( 10 ) E198 - E198 2013.3

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DOI： 10.1016/S0735-1097(13)60199-0

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E/e' Two Weeks after Onset Is a Powerful Predictor of Cardiac Death and Heart Failure in Patients with a First-Time ST Elevation Acute Myocardial Infarction

Noriaki Iwahashi, Kazuo Kimura, Masami Kosuge, Kengo Tsukahara, Kiyoshi Hibi, Toshiaki Ebina, Mari Saito, Satoshi Umemura

JOURNAL OF THE AMERICAN SOCIETY OF ECHOCARDIOGRAPHY 25 ( 12 ) 1290 - 1298 2012.12

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DOI： 10.1016/j.echo.2012.09.010

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急性冠症候群に対する治療戦略非ST上昇型急性冠症候群の臨床像

田原良雄, 木村一雄, 小菅雅美, 海老名俊明, 日比潔, 塚原健吾, 岩橋徳明, 前島信彦, 遠藤光明

日本冠疾患学会雑誌 18 ( 4 ) 323 - 323 2012.12

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画像診断を治療に活かす IVUSを如何に治療に活かすか

日比潔, 遠藤光明, 坂賢一郎, 前島信彦, 松澤泰志, 田原良雄, 塚原健吾, 岩橋徳明, 岡田興造, 住田晋一, 小西正紹, 鈴木弘之, 海老名俊明, 梅村敏, 木村一雄

日本冠疾患学会雑誌 18 ( 4 ) 332 - 332 2012.12

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血糖変動と冠動脈プラーク組織性状との関係急性冠症候群患者における検討

岡田興造, 日比潔, 永嶋善幸, 郷原正臣, 秋山英一, 松澤泰志, 小西正紹, 坂賢一郎, 遠藤光明, 前島信彦, 岩橋徳明, 塚原健吾, 小菅雅美, 海老名俊明, 木村一雄

日本冠疾患学会雑誌 18 ( 4 ) 407 - 407 2012.12

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Left Ventricular Filling Pressure Assessed by E/e ' of Women is Higher than Men in Patients with a First ST Elevation Acute Myocardial Infarction

Noriaki Iwahashi, Kazuo Kimura, Masaomi Gohbara, Mistauaki Endo, Nobihiko Maejima, Kengo Tsukahara, Yoshio Tahara, Kiyoshi Hibi, Masami Kosuge, Toshiaki Ebina, Shinichi Sumita, Toshiyuki Ishikawa, Kazuaki Uchino, Satoshi Umemura

CIRCULATION 126 ( 21 ) 2012.11

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Left Ventricular Dyssynchrony Estimated by 3D Speckle Tracking Echocardiography Acutely Onset after ST-Elevation Myocardial Infarction Predicts Final Infarct Size and Remodeling

Noriaki Iwahashi, Kazuo Kimura, Masaomi Gohbara, Zenko Nagashima, Kozo Okada, Mistuaki Endo, Nobuhiko Maejima, Kengo Tsukahara, Yoshio Tahara, Kiyoshi Hibi, Masami Kosuge, Toshiaki Ebina, Taro Hattori, Mochizuki Hidekazu, Atsuyoshi Miyauchi, Yukiko Ouchi, Eiji Ishikawa, Satoshi Umemura

CIRCULATION 126 ( 21 ) 2012.11

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非ST上昇型急性冠症候群における責任病変形態と入院後の高感度CRP(hs-CRP)上昇との関係 OCTを用いた検討

坂賢一郎, 前島信彦, 日比潔, 鈴木弘之, 永嶋善幸, 岡田興造, 松澤泰志, 岩橋徳明, 遠藤光明, 塚原健吾, 田原良雄, 小菅雅美, 海老名俊明, 梅村敏, 木村一雄

日本心臓病学会誌 7 ( Suppl.I ) 316 - 316 2012.8

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Hypertensive Acute Heart Failure Syndromeに認められた奇異性血液濃縮

小西正紹, 木村一雄, 海老名俊明, 小菅雅美, 日比潔, 塚原健吾, 岩橋徳明, 遠藤光明, 前島信彦, 坂賢一郎, 羽柴克孝, 岡田興造, 松澤泰志, 郷原正臣, 永嶋善幸, 梅村敏

日本心臓病学会誌 7 ( Suppl.I ) 330 - 330 2012.8

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たこつぼ型心筋症と再灌流後の非Q波急性前壁梗塞の陰性T波の違い

小菅雅美, 海老名俊明, 日比潔, 塚原健吾, 岩橋徳明, 前島信彦, 遠藤光明, 松澤泰志, 岡田興造, 小西正紹, 梅村敏, 木村一雄

日本心臓病学会誌 7 ( Suppl.I ) 331 - 331 2012.8

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急性前壁梗塞における入院時QRSスコアと再灌流後の微小循環障害との関係

小菅雅美, 海老名俊明, 日比潔, 塚原健吾, 岩橋徳明, 前島信彦, 遠藤光明, 松澤泰志, 岡田興造, 郷原正臣, 梅村敏, 木村一雄

日本心臓病学会誌 7 ( Suppl.I ) 331 - 331 2012.8

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急性心筋梗塞緊急冠動脈造影検査施行例における造影剤腎症と長期予後との関係

清國雅義, 小菅雅美, 松澤泰志, 前島信彦, 遠藤光明, 岩橋徳明, 塚原健吾, 田原良雄, 日比潔, 海老名俊明, 住田晋一, 猿渡力, 梅村敏, 木村一雄

日本心臓病学会誌 7 ( Suppl.I ) 431 - 431 2012.8

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急性冠症候群非責任病変プラークにおける性差 OCTを用いた検討

前島信彦, 坂賢一郎, 日比潔, 岩橋徳明, 遠藤光明, 塚原健吾, 田原良雄, 小菅雅美, 海老名俊明, 梅村敏, 木村一雄

日本心臓病学会誌 7 ( Suppl.I ) 465 - 465 2012.8

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ST上昇型心筋梗塞患者における至適薬物療法下での血管内皮機能障害規定因子の検討

鈴木弘之, 松澤泰志, 小西正紹, 秋山英一, 岡田興造, 坂賢一郎, 前島信彦, 遠藤光明, 岩橋徳明, 塚原健吾, 日比潔, 小菅雅美, 海老名俊明, 梅村敏, 木村一雄

日本心臓病学会誌 7 ( Suppl.I ) 472 - 472 2012.8

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3次元超音波でのDyssynchronyは初回ST上昇型急性心筋梗塞の梗塞サイズの推定とリモデリング予測に有用である

岩橋徳明, 木村一雄, 郷原正臣, 遠藤光明, 前島信彦, 塚原健吾, 田原良雄, 日比潔, 小菅雅美, 海老名俊明, 梅村敏

日本心臓病学会誌 7 ( Suppl.I ) 506 - 506 2012.8

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Real-time 3D Echocardiographyを用いた左室重量測定の有用性の検討心臓MRIとの検証

郷原正臣, 岩橋徳明, 前島信彦, 遠藤光明, 塚原健吾, 田原良雄, 日比潔, 小菅雅美, 海老名俊明, 梅村敏, 木村一雄

日本心臓病学会誌 7 ( Suppl.I ) 341 - 341 2012.8

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Real-Time 3D Echocardiographyを用いた右室機能解析の有用性の検討心臓MRIとの検証

郷原正臣, 岩橋徳明, 前島信彦, 遠藤光明, 塚原健吾, 田原良雄, 日比潔, 小菅雅美, 海老名俊明, 梅村敏, 木村一雄

日本心臓病学会誌 7 ( Suppl.I ) 405 - 405 2012.8

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3次元スペックルトラッキング法は初回ST上昇型急性心筋梗塞における梗塞サイズの推定に有用である

岩橋徳明, 木村一雄, 遠藤光明, 海老名俊明, 郷原正臣, 小菅雅美, 前島信彦, 田原良雄, 日比潔, 梅村敏

日本心臓病学会誌 7 ( Suppl.I ) 407 - 407 2012.8

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INFLUENCE OF ACCESS SITE AND ENHANCED RESPONSE TO ANTIPLATELET THERAPY ON ACCESS SITE BLEEDING IN PATIENTS UNDERGOING PERCUTANEOUS CORONARY INTERVENTION

Kengo Tsukahara, Kazuo Kimura, Toshiaki Ebina, Masami Kosuge, Kiyoshi Hibi, Noriaki Iwahashi, Mitsuaki Endo, Nobuhiko Maejima, Satoshi Umemura

JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY 59 ( 13 ) E1407 - E1407 2012.3

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DOI： 10.1016/S0735-1097(12)61408-9

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LEFT VENTRICULAR DYSSYNCHRONY ESTIMATED BY REAL TIME 3D ECHOCARDIOGRAPHY ACUTELY ONSET AFTER ST-ELEVATION MYOCARDIAL INFARCTION PREDICTS FINAL INFARCT SIZE AND LEFT VENTRICULAR REMODELING

Noriaki Iwahashi, Masami Kosuge, Mitsuaki Endo, Nobuhiko Maejima, Kengo Tsukahara, Kiyoshi Hibi, Toshiaki Ebina, Satoshi Umemura, Kazuo Kimura

JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY 59 ( 13 ) E1114 - E1114 2012.3

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DOI： 10.1016/S0735-1097(12)61115-2

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Elevated Heart Rate Two Weeks after Onset, Despite Successful Reperfusion Therapy, Indicates Poor Prognosis in Patients with a First ST-Elevation Acute Myocardial Infarction

Noriaki Iwahashi, Masami Kosuge, Mitsuaki Endo, Nobuhiko Maejima, Kengo Tsukahara, Yoshio Tahara, Kiyoshi Hibi, Toshiaki Ebina, Shinichi Sumita, Toshiyuki Ishikawa, Kazuaki Uchino, Satoshi Umemura, Kazuo Kimura

CIRCULATION 124 ( 21 ) 2011.11

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急性冠症候群における冠動脈多枝病変と責任病変の形態との関係 OCTを用いた研究

坂賢一郎, 日比潔, 前島信彦, 岡田興造, 松澤泰志, 遠藤光明, 岩橋徳明, 塚原健吾, 小菅雅美, 海老名正明, 梅村敏, 木村一雄

日本冠疾患学会雑誌 17 ( 4 ) 364 - 364 2011.11

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Left Ventricular Dyssynchrony Estimated by Real time 3D Echocardiography Acutely Onset after ST-Elevation Myocardial Infarction Predicts Left Ventricular Remodeling

Noriaki Iwahashi, Masami Kosuge, Nobuhiko Maejima, Mitsuaki Endo, Kengo Tsukahara, Yoshio Tahara, Kiyoshi Hibi, Toshiaki Ebina, Shinichi Sumita, Kazuaki Uchino, Toshiyuki Ishikawa, Satoshi Umemura, Kazuo Kimura

CIRCULATION 124 ( 21 ) 2011.11

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Usefulness of Plasma B-Type Natriuretic Peptide in the Assessment of Disease Severity and Prediction of Outcome after Aortic Valve Replacement in Patients with Severe Aortic Stenosis

Noriaki Iwahashi, Satoshi Nakatani, Satoshi Umemura, Kazuo Kimura, Masafumi Kitakaze

JOURNAL OF THE AMERICAN SOCIETY OF ECHOCARDIOGRAPHY 24 ( 9 ) 984 - 991 2011.9

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DOI： 10.1016/j.echo.2011.03.012

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糖尿病の既往のない急性冠症候群症例における高インスリン血症と病変形態との関係 OCTを用いた検討

坂賢一郎, 日比潔, 前島信彦, 岡田興造, 松澤泰志, 小西正紹, 羽柴克孝, 岩橋徳明, 遠藤光明, 塚原健吾, 小菅雅美, 海老名俊明, 梅村敏, 木村一雄

日本心臓病学会誌 6 ( Suppl.I ) 251 - 251 2011.8

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急性心筋梗塞緊急冠動脈造影施行例において造影剤腎症の定義が及ぼす影響についての検討

清國雅義, 小菅雅美, 猿渡力, 海老名俊明, 日比潔, 田原良雄, 塚原健吾, 岩橋徳明, 遠藤光明, 前島信彦, 梅村敏, 木村一雄

日本心臓病学会誌 6 ( Suppl.I ) 266 - 266 2011.8

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冠動脈ステント留置術後の心血管事故の指標としての血小板反応性と炎症マーカー

塚原健吾, 木村一雄, 海老名俊明, 小菅雅美, 日比潔, 岩橋徳明, 遠藤光明, 前島信彦, 坂賢一郎, 羽柴克孝, 小西正紹, 松澤泰志, 岡田興造, 梅村敏

日本心臓病学会誌 6 ( Suppl.I ) 290 - 290 2011.8

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ACS患者における耐糖能障害はインクレチン低反応と関連する

小西正紹, 木村一雄, 住田晋一, 海老名俊明, 日比潔, 遠藤光明, 塚原健吾, 岩橋徳明, 前島信彦, 松澤泰志, 坂賢一郎, 羽柴克孝, 岡田興造, 鈴木弘之, 小菅雅美, 梅村敏

日本心臓病学会誌 6 ( Suppl.I ) 321 - 321 2011.8

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E/e'とQRSスコアを組み合わせて検討することは初回ST上昇型急性心筋梗塞の予後予測に有用である

岩橋徳明, 小菅雅美, 鈴木弘之, 岡田興造, 羽柴克孝, 坂賢一郎, 小西正紹, 遠藤光明, 前島信彦, 塚原健吾, 田原良雄, 日比潔, 海老名俊明, 梅村敏, 木村一雄

日本心臓病学会誌 6 ( Suppl.I ) 434 - 434 2011.8

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狭心症患者における責任病変の組織性状に対する推定糸球体濾過量(eGFR)と高感度CRP(hs-CRP)の影響について

坂賢一郎, 日比潔, 前島信彦, 岡田興造, 松澤泰志, 小西正紹, 羽柴克孝, 遠藤光明, 岩橋徳明, 塚原健吾, 小菅雅美, 海老名俊明, 梅村敏, 木村一雄

日本心臓病学会誌 6 ( Suppl.I ) 471 - 471 2011.8

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再灌流療法に成功した初回ST上昇型急性心筋梗塞の予後予測における慢性期の心拍数の意義

岩橋徳明, 小菅雅美, 坂賢一郎, 羽柴克孝, 前島信彦, 遠藤光明, 塚原健吾, 田原良雄, 日比潔, 海老名俊明, 梅村敏, 木村一雄

日本心臓病学会誌 6 ( Suppl.I ) 489 - 489 2011.8

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再灌流療法に成功した初回ST上昇型急性心筋梗塞においてE/e'は女性において高値である

岩橋徳明, 小菅雅美, 羽柴克孝, 坂賢一郎, 遠藤光明, 前島信彦, 塚原健吾, 田原良雄, 日比潔, 海老名俊明, 梅村敏, 木村一雄

日本心臓病学会誌 6 ( Suppl.I ) 429 - 429 2011.8

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高感度アッセイにより検出された、急性心筋梗塞プレコンディショニングに伴う超急性期の微小なトロポニン上昇

小西正紹, 木村一雄, 住田晋一, 海老名俊明, 遠藤光明, 日比潔, 塚原健吾, 岩橋徳明, 前島信彦, 松澤泰志, 坂賢一郎, 羽柴克孝, 岡田興造, 鈴木弘之, 小菅雅美, 梅村敏

日本心臓病学会誌 6 ( Suppl.I ) 243 - 243 2011.8

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非ST上昇型急性冠症候群における重症左主幹部/3枝病変の判別

小菅雅美, 海老名俊明, 日比潔, 岩橋徳明, 前島信彦, 遠藤光明, 塚原健吾, 坂賢一郎, 羽柴克孝, 松澤泰志, 小西正紹, 岡田興造, 永嶋善幸, 梅村敏, 木村一雄

日本心臓病学会誌 6 ( Suppl.I ) 244 - 244 2011.8

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Impact of concomitant use of proton-pump inhibitors and thienopyridine derivatives on the antiplatelet effects

Kengo Tsukahara, Kazuo Kimura, Satoshi Morita, Toshiaki Ebina, Masami Kosuge, Kiyoshi Hibi, Noriaki Iwahashi, Mitsuaki Endo, Nobuhiko Maejima, Teruyasu Sugano, Satoshi Umemura

JOURNAL OF CARDIOLOGY 57 ( 3 ) 275 - 282 2011.5

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DOI： 10.1016/j.jjcc.2011.01.003

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ASSESSMENT OF MORPHOLOGICAL FEATURES OF PLAQUES WITH ULTRASOUND ATTENUATION IN PATIENTS WITH ACUTE CORONARY SYNDROME USING OPTICAL COHERENCE TOMOGRAPHY

Nobuhiko Maejima, Kiyoshi Hibi, Kenichiro Saka, Hiroyuki Suzuki, Zenkou Nagashima, Naoki Nakayama, Masayoshi Kiyokuni, Kozo Okada, Yasushi Matsuzawa, Masaaki Konishi, Katsutaka Hashiba, Mitsuaki Endo, Noriaki Iwahashi, Kengo Tsukahara, Yoshio Tahara, Masami Kosuge, Toshiaki Ebina, Satoshi Umemura, Kazuo Kimura

JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY 57 ( 14 ) E1741 - E1741 2011.4

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DOI： 10.1016/S0735-1097(11)61741-5

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LEFT ATRIAL VOLUME INDEX (LAVI) OVER LATE DIASTOLIC MITRAL ANNULAR VELOCITY (A') IS A POWERFUL PREDICTOR OF CARDIAC DEATH AND CONGESTIVE HEART FAILURE (CHF) IN PATIENTS WITH A FIRST ST-ELEVATION ACUTE MYOCARDIAL INFARCTION (STEMI)

Noriaki Iwahashi, Masami Kosuge, Mitsuaki Endo, Nobuhiko Maejima, Kengo Tsukahara, Yoshio Tahara, Kiyoshi Hibi, Toshiaki Ebina, Shinichi Sumita, Satoshi Umemura, Kazuo Kimura

JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY 57 ( 14 ) E702 - E702 2011.4

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DOI： 10.1016/S0735-1097(11)60702-X

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THE RELATIONSHIP BETWEEN HIGH ON-TREATMENT PLATELET REACTIVITY AND RAPID ANGIOGRAPHIC PROGRESSION OF NON-CULPRIT CORONARY LESIONS IN PATIENTS WITH ACUTE CORONARY SYNDROMES

Kengo Tsukahara, Kazuo Kimura, Toshiaki Ebina, Masami Kosuge, Kiyoshi Hibi, Noriaki Iwahashi, Mitsuaki Endo, Nobuhiko Maejima, Satoshi Umemura

JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY 57 ( 14 ) E928 - E928 2011.4

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DOI： 10.1016/S0735-1097(11)60928-5

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当院における経皮的心肺補助法を要した重症肺塞栓症の治療実績

羽柴克孝, 海老名俊明, 小菅雅美, 日比潔, 塚原健吾, 岩橋徳明, 遠藤光明, 前島信彦, 木村一雄, 猿渡力

心臓 43 ( 7 ) 977 - 977 2011

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DOI： 10.11281/shinzo.43.977

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High-Response to Antiplatelet Therapy and the Increasing Risk of Bleeding

Kengo Tsukahara, Kazuo Kimura, Toshiaki Ebina, Masami Kosuge, Kiyoshi Hibi, Noriaki Iwahashi, Nobuhiko Maejima, Mitsuaki Endo, Satoshi Umemura

CIRCULATION 122 ( 21 ) 2010.11

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ACSに対する再還流療法の現状と問題点都市部における急性心筋梗塞に対する再灌流療法の現状と問題点

遠藤光明, 岡田興造, 松澤泰志, 羽柴克孝, 小西正紹, 坂賢一郎, 前島信彦, 岩橋徳明, 塚原健吾, 日比潔, 田原良雄, 小菅雅美, 海老名俊明, 梅村敏, 木村一雄

日本冠疾患学会雑誌 16 ( 4 ) 289 - 289 2010.11

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急性心筋梗塞緊急冠動脈施行例で急性期高血糖は造影剤腎症発症の予測因子である

清國雅義, 小菅雅美, 海老名俊明, 日比潔, 塚原健吾, 岩橋徳明, 遠藤光明, 前島信彦, 坂賢一郎, 羽柴克孝, 小西正明, 松澤泰志, 岡田興造, 中山尚貴, 木村一雄

日本冠疾患学会雑誌 16 ( 4 ) 393 - 393 2010.11

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Left Atrial Volume Index (LAVI) over Late Diastolic Mitral Annular Velocity (a') is a Powerful Predictor of Cardiac Death and Heart Failure in Patients with a First ST Elevation Acute Myocardial Infarction

Noriaki Iwahashi, Masami Kosuge, Mitsuaki Endo, Nobuhiko Maejima, Kengo Tsukahara, Yoshio Tahara, Kiyoshi Hibi, Toshiaki Ebina, Shinichi Sumita, Satoshi Umemura, Kazuo Kimura

CIRCULATION 122 ( 21 ) 2010.11

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初回ST上昇型急性心筋梗塞における入院時Apo-B/A-1比の臨床的意義

岩橋徳明, 小菅雅美, 羽柴克孝, 坂賢一郎, 松澤泰志, 清國雅義, 前島信彦, 岡田興造, 中山尚貴, 塚原健吾, 田原良雄, 日比潔, 海老名俊明, 梅村敏, 木村一雄

日本心臓病学会誌 5 ( Suppl.I ) 482 - 482 2010.8

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急性冠症候群非責任病変におけるプラークの組織学的特徴 IB-IVUSおよびOCTを用いた検討

前島信彦, 日比潔, 坂賢一郎, 中山尚貴, 遠藤光明, 岩橋徳明, 塚原健吾, 田原良雄, 小菅雅美, 海老名俊明, 梅村敏, 木村一雄

日本心臓病学会誌 5 ( Suppl.I ) 234 - 234 2010.8

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陰性T波によるたこつぼ型心筋症と再疎通後の急性前壁梗塞の鑑別法

小菅雅美, 海老名俊明, 日比潔, 岩橋徳明, 塚原健吾, 前島信彦, 田原良雄, 坂賢一郎, 羽柴克孝, 清國雅義, 中山尚貴, 松澤泰志, 木村一雄, 梅村敏

日本心臓病学会誌 5 ( Suppl.I ) 288 - 288 2010.8

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冠動脈ステント留置術における潰瘍治療薬の使用と消化管出血および心血管事故

塚原健吾, 木村一雄, 海老名俊明, 小菅雅美, 日比潔, 岩橋徳明, 前島信彦, 羽柴克孝, 松澤泰志, 清國雅義, 中山尚貴, 菅野晃靖, 梅村敏

日本心臓病学会誌 5 ( Suppl.I ) 290 - 290 2010.8

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急性心筋梗塞緊急冠動脈造影施行例における急性期高血糖と造影剤腎症の発症との関係

清國雅義, 小菅雅美, 海老名俊明, 日比潔, 田原良雄, 塚原健吾, 岩橋徳明, 前島信彦, 遠藤光明, 木村一雄, 梅村敏

日本心臓病学会誌 5 ( Suppl.I ) 329 - 329 2010.8

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急性前壁梗塞発症時に嘔気・嘔吐を認める例の臨床像

小菅雅美, 海老名俊明, 日比潔, 岩橋徳明, 前島信彦, 遠藤光明, 塚原健吾, 田原良雄, 坂賢一郎, 羽柴克孝, 清國雅義, 松澤泰志, 木村一雄, 梅村敏

日本心臓病学会誌 5 ( Suppl.I ) 338 - 338 2010.8

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急性冠症候群における酸化ストレスと抗酸化力の動態に関する検討

南一敏, 小菅雅美, 海老名俊明, 日比潔, 塚原健吾, 岩橋徳明, 大塚文之, 猿渡力, 木村一雄, 梅村敏

日本心臓病学会誌 5 ( Suppl.I ) 375 - 375 2010.8

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狭心症患者における推定糸球体濾過量(eGFR)と責任病変のプラーク性状との関係 IB-IVUSとOCTを用いた検討

坂賢一郎, 日比潔, 前島信彦, 中山尚貴, 清國雅義, 羽柴克孝, 大塚文之, 岩橋徳明, 塚原健吾, 小菅雅美, 海老名俊明, 梅村敏, 木村一雄

日本心臓病学会誌 5 ( Suppl.I ) 431 - 431 2010.8

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初回ST上昇型急性心筋梗塞における下大静脈(IVC)径とE/e'の組み合わせの有用性

岩橋徳明, 羽柴克孝, 海老名俊明, 坂賢一郎, 小菅雅美, 松澤泰志, 岡田興造, 前島信彦, 大塚文之, 中山尚貴, 塚原健吾, 田原良雄, 日比潔, 梅村敏, 木村一雄

日本心臓病学会誌 5 ( Suppl.I ) 467 - 467 2010.8

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頸動脈内中膜複合体は初回ST上昇型急性心筋梗塞における予後規定因子である

岩橋徳明, 小菅雅美, 岡田興造, 清國雅義, 羽柴克孝, 小西正紹, 塚原健吾, 前島信彦, 田原良雄, 日比潔, 海老名俊明, 坂賢一郎, 松澤泰志, 梅村敏, 木村一雄

日本心臓病学会誌 5 ( Suppl.I ) 311 - 311 2010.8

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Impact of High-Responsiveness to Dual Antiplatelet Therapy on Bleeding Complications in Patients Receiving Drug-Eluting Stents

Kengo Tsukahara, Kazuo Kimura, Satoshi Morita, Toshiaki Ebina, Masami Kosuge, Kiyoshi Hibi, Jun Okuda, Noriaki Iwahashi, Nobuhiko Maejima, Tatsuya Nakachi, Fumiyuki Ohtsuka, Katsutaka Hashiba, Yoshio Tahara, Teruyasu Sugano, Satoshi Umemura

CIRCULATION JOURNAL 74 ( 4 ) 679 - 685 2010.4

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DOI： 10.1253/circj.CJ-09-0601

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ペースメーカー治療を行った嚥下性失神の1例

峯岸裕蔵, 中山尚貴, 住田晋一, 小菅雅美, 岩橋徳明, 奥田純, 塚原健吾, 日比潔, 海老名俊明, 木村一雄

日本内科学会関東地方会 569回 51 - 51 2010.2

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Impact of the ApoB/A1-Ratio on the Prediction of the Elevation of Left Ventricular Filling Pressure After a First STEMI

Noriaki Iwahashi, Masami Kosuge, Jun Okuda, Kengo Tsukahara, Yoshio Tahara, Kiyoshi Hibi, Toshiaki Ebina, Shinichi Sumita, Toshiaki Ishikawa, Kazuaki Uchino, Satoshi Umemura, Kazuo Kimura

CIRCULATION 120 ( 18 ) S489 - S489 2009.11

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Prognostic Implications of Left Ventricular Mass and Geometry Following a First ST-Elevation Acute Myocardial Infarction

Noriaki Iwahashi, Masami Kosuge, Jun Okuda, Kengo Tsukahara, Yoshio Tahara, Kiyoshi Hibi, Toshiaki Ebina, Shinichi Sumita, Toshiaki Ishikawa, Kazuaki Uchino, Satoshi Umemura, Satoshi Umemura, Kazuo Kimura

CIRCULATION 120 ( 18 ) S356 - S356 2009.11

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Web of Science

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急性冠症候群非責任病変におけるプラークの組織学的特徴 OCTを用いた検討

前島信彦, 日比潔, 中山尚貴, 小村直弘, 坂賢一郎, 大塚文之, 岩橋徳明, 奥田純, 塚原健吾, 小菅雅美, 海老名俊明, 木村一雄

日本冠疾患学会雑誌 15 ( 4 ) 376 - 376 2009.11

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非ST上昇型急性冠症候群における腎障害と冠動脈硬化病変の進行との関係

仲地達哉, 小菅雅美, 日比潔, 海老名俊明, 塚原健吾, 奥田純, 岩橋徳明, 田原良雄, 木村一雄

日本冠疾患学会雑誌 15 ( 4 ) 353 - 353 2009.11

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急性冠症候群患者におけるスタチン投与によるLDLコレステロール/HDLコレステロール比の変化とプラーク体積の変化の検討

小村直弘, 日比潔, 中山尚貴, 清國雅義, 南一敏, 羽柴克孝, 大塚文之, 仲地達哉, 前島信彦, 岩橋徳明, 奥田純, 塚原健吾, 小菅雅美, 海老名俊明, 梅村敏, 木村一雄

日本心臓病学会誌 4 ( Suppl.I ) 282 - 282 2009.8

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狭心症責任病変プラーク組織性状は血清HDL-C値とCRP値と関連する integrated backscatter intravascular ultrasound(IB-IVUS)での検討

中山尚貴, 日比潔, 清國雅義, 南一敏, 小村直弘, 羽柴克孝, 大塚文之, 仲地達哉, 前島信彦, 岩橋徳明, 奥田純, 塚原健吾, 小菅雅美, 海老名俊明, 梅村敏, 木村一雄

日本心臓病学会誌 4 ( Suppl.I ) 282 - 282 2009.8

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チエノピリジン誘導体とプロトンポンプ阻害薬の併用例における血小板凝集能

塚原健吾, 木村一雄, 海老名俊明, 菅野晃靖, 小菅雅美, 日比潔, 奥田純, 岩橋徳明, 前島信彦, 仲地達哉, 大塚文之, 羽柴克孝, 梅村敏

日本心臓病学会誌 4 ( Suppl.I ) 286 - 286 2009.8

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急性冠症候群責任病変における血管内超音波で認める超音波減衰性プラークのOCTによる組織学的特徴

前島信彦, 日比潔, 中山尚貴, 小村直弘, 羽柴克孝, 坂賢一郎, 大塚文之, 仲地達哉, 岩橋徳明, 奥田純, 塚原健吾, 田原良雄, 小菅雅美, 海老名俊明, 梅村敏, 木村一雄

日本心臓病学会誌 4 ( Suppl.I ) 303 - 303 2009.8

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急性心筋梗塞血栓溶解療法施行例で急性期高血糖は梗塞前狭心症による梗塞サイズ縮小効果を減弱させる

清國雅義, 小菅雅美, 海老名俊明, 日比潔, 塚原健吾, 奥田純, 岩橋徳明, 前島信彦, 仲地達哉, 大塚文之, 羽柴克孝, 小村直弘, 南一敏, 中山尚貴, 木村一雄, 梅村敏

日本心臓病学会誌 4 ( Suppl.I ) 311 - 311 2009.8

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E/e'を含む組織ドプラー法指標は初回急性前壁梗塞において強力な予後規定因子である

岩橋徳明, 小菅雅美, 清國雅義, 南一敏, 小村直弘, 羽柴克孝, 大塚文之, 仲地達哉, 前島信彦, 奥田純, 塚原健吾, 田原良雄, 日比潔, 海老名俊明

日本心臓病学会誌 4 ( Suppl.I ) 312 - 312 2009.8

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右室組織ドプラー法の初回ST上昇型急性心筋梗塞の評価における活用法に関する検討

岩橋徳明, 小菅雅美, 南一敏, 中山尚貴, 小村直弘, 羽柴克孝, 大塚文之, 仲地達哉, 前島信彦, 奥田純, 塚原健吾, 田原良雄, 日比潔, 海老名俊明, 梅村敏, 木村一雄

日本心臓病学会誌 4 ( Suppl.I ) 357 - 357 2009.8

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急性心筋梗塞発症前のスタチン内服は造影剤腎症の発症リスクを低下させる

清國雅義, 小菅雅美, 海老名俊明, 日比潔, 塚原健吾, 奥田純, 岩橋徳明, 前島信彦, 仲地達哉, 大塚文之, 羽柴克孝, 小村直弘, 南一敏, 中山尚貴, 木村一雄, 梅村敏

日本心臓病学会誌 4 ( Suppl.I ) 390 - 390 2009.8

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初回ST上昇型急性心筋梗塞における組織ドプラー法諸指標の有用性に関する検討

岩橋徳明, 小菅雅美, 小村直弘, 中山尚貴, 南一敏, 羽柴克孝, 大塚文之, 仲地達哉, 前島信彦, 奥田純, 塚原健吾, 田原良雄, 日比潔, 海老名俊明, 梅村敏, 木村一雄

日本心臓病学会誌 4 ( Suppl.I ) 396 - 396 2009.8

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初回ST上昇型急性心筋梗塞における心臓超音波諸指標とBNPの関係

岩橋徳明, 小菅雅美, 中山尚貴, 清國雅義, 小村直弘, 羽柴克孝, 大塚文之, 仲地達哉, 前島信彦, 奥田純, 塚原健吾, 田原良雄, 日比潔, 海老名俊明, 梅村敏, 木村一雄

日本心臓病学会誌 4 ( Suppl.I ) 398 - 398 2009.8

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経皮的心肺補助法を要した重症肺塞栓と急性心筋梗塞の比較

羽柴克孝, 奥田純, 海老名俊明, 小菅雅美, 日比潔, 塚原健吾, 岩橋徳明, 前島信彦, 仲地達哉, 大塚文之, 坂賢一郎, 田原良雄, 梅村敏, 木村一雄

日本心臓病学会誌 4 ( Suppl.I ) 447 - 447 2009.8

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非ST上昇型急性冠症候群における腎機能障害と冠動脈硬化病変の進行との関係

仲地達哉, 小菅雅美, 日比潔, 海老名俊明, 塚原健吾, 奥田純, 岩橋徳明, 田原良雄, 梅村敏, 木村一雄

日本心臓病学会誌 4 ( Suppl.I ) 204 - 204 2009.8

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来院時完全右脚ブロックを合併した左主幹部を責任病変とする急性心筋梗塞症の臨床像

奥田純, 小菅雅美, 住田晋一, 海老名俊明, 日比潔, 田原良雄, 塚原健吾, 岩橋徳明, 梅村敏, 木村一雄

日本心臓病学会誌 4 ( Suppl.I ) 205 - 205 2009.8

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急性下壁梗塞におけるV4R誘導のST上昇による右室虚血診断の問題点

小菅雅美, 海老名俊明, 日比潔, 奥田純, 岩橋徳明, 塚原健吾, 大塚文之, 前島信彦, 羽柴克孝, 清國雅義, 南一敏, 仲地達哉, 中山尚貴, 小村直弘, 木村一雄, 梅村敏

日本心臓病学会誌 4 ( Suppl.I ) 205 - 205 2009.8

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非糖尿病の急性心筋梗塞症例における耐糖能障害と冠動脈リモデリングとの関連

大塚文之, 日比潔, 小菅雅美, 小村直弘, 前島信彦, 仲地達哉, 羽柴克孝, 岩橋徳明, 奥田純, 塚原健吾, 田原良雄, 海老名俊明, 梅村敏, 木村一雄

日本心臓病学会誌 4 ( Suppl.I ) 234 - 234 2009.8

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肺動脈弁感染性心内膜炎の診断にリアルタイム3D経食道心臓超音波検査が有用であった一例

岩橋徳明, 小菅雅美, 羽柴克孝, 南一敏, 清國雅義, 前島信彦, 大塚文之, 中山尚貴, 仲地達哉, 奥田純, 塚原健吾, 田原良雄, 日比潔, 海老名俊明, 梅村敏, 木村一雄

日本心臓病学会誌 4 ( Suppl.I ) 240 - 240 2009.8

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電気的除細動抵抗性心室細動に対するアミオダロン使用例の検討

田原良雄, 鈴木範行, 坂賢一郎, 松澤泰志, 清國雅義, 南一敏, 中山尚貴, 羽柴克孝, 前島信彦, 岩橋徳明, 塚原健吾, 奥田純, 日比潔, 海老名俊明, 木村一雄, 梅村敏

日本心臓病学会誌 4 ( Suppl.I ) 242 - 242 2009.8

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急性冠症候群非責任病変におけるプラークの組織学的特徴 OCTを用いた検討

前島信彦, 日比潔, 中山尚貴, 小村直弘, 羽柴克孝, 坂賢一郎, 大塚文之, 仲地達哉, 岩橋徳明, 奥田純, 塚原健吾, 田原良雄, 小菅雅美, 海老名俊明, 梅村敏, 木村一雄

日本心臓病学会誌 4 ( Suppl.I ) 245 - 245 2009.8

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重症肺塞栓症の治療における経皮的心肺補助法の有効性の検討

羽柴克孝, 奥田純, 海老名俊明, 小菅雅美, 日比潔, 塚原健吾, 岩橋徳明, 木村一雄, 猿渡力

Therapeutic Research 30 ( 5 ) 644 - 644 2009.5

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Tissue Doppler Imaging Including E/e ' Is a Powerful Predictor of Major Adverse Cardio Cerebrovascular Events in Patients With a First Anterior ST-Elevation Acute Myocardial Infarction

Noriaki Iwahashi, Masami Kosuge, Jun Okuda, Kengo Tsukahara, Yoshio Tahara, Kiyoshi Hibi, Toshiaki Ebina, Shinichi Sumita, Toshiyuki Ishikawa, Kazuaki Uchino, Satoshi Umemura, Kazuo Kimura

JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY 53 ( 10 ) A234 - A234 2009.3

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急性前壁梗塞における急性期の白血球数増加と再疎通後の左室機能との関係

小菅雅美, 海老名俊明, 日比潔, 塚原健吾, 奥田純, 岩橋徳明, 仲地達哉, 梅村敏, 木村一雄

日本冠疾患学会雑誌 14 ( 4 ) 380 - 380 2008.11

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待機的PCIにおける血小板凝集能亢進例の検討

塚原健吾, 木村一雄, 海老名俊明, 小菅雅美, 日比潔, 奥田純, 岩橋徳明, 田原良雄, 梅村敏

日本冠疾患学会雑誌 14 ( 4 ) 367 - 367 2008.11

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非ST上昇型急性冠症候群の急性期に認める一過性肝障害についての検討

仲地達哉, 小菅雅美, 海老名俊明, 日比潔, 塚原健吾, 奥田純, 岩橋徳明, 梅村敏, 木村一雄

日本冠疾患学会雑誌 14 ( 4 ) 380 - 380 2008.11

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Hyper-Responder to Dual Antiplatelet Therapy and Bleeding Complications

Kengo Tsukahara, Kazuo Kimura, Toshiaki Ebina, Masami Kosuge, Kiyoshi Hibi, Jun Okuda, Noriaki Iwahashi, Satoshi Umemura

CIRCULATION 118 ( 18 ) S477 - S477 2008.10

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たこつぼ型心筋症に心室中隔穿孔を合併した一例

南一敏, 小菅雅美, 岩橋徳明, 奥田純, 塚原健吾, 日比潔, 海老名俊明, 梅村敏, 木村一雄, 河合祥雄

日本心臓病学会誌 2 ( Suppl.I ) 310 - 310 2008.8

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ST上昇型急性心筋梗塞症における冠動脈プラーク破裂とHDLコレステロール値及び喫煙との関連

大塚文之, 日比潔, 草間郁好, 遠藤光明, 三橋孝之, 小村直弘, 小菅雅美, 岩橋徳明, 奥田純, 塚原健吾, 田原良雄, 海老名俊明, 梅村敏, 木村一雄

日本心臓病学会誌 2 ( Suppl.I ) 363 - 363 2008.8

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急性下壁梗塞におけるV5-6誘導のST上昇の臨床的意義

小菅雅美, 海老名俊明, 日比潔, 奥田純, 岩橋徳明, 塚原健吾, 大塚文之, 羽柴克孝, 清國雅義, 南一敏, 木村一雄, 梅村敏

日本心臓病学会誌 2 ( Suppl.I ) 404 - 404 2008.8

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非ST上昇型急性冠症候群冠インターベンション施行例における非責任病変の冠動脈硬化進展の規定因子

仲地達哉, 小菅雅美, 日比潔, 海老名俊明, 塚原健吾, 奥田純, 岩橋徳明, 田原良雄, 梅村敏, 木村一雄

日本心臓病学会誌 2 ( Suppl.I ) 434 - 434 2008.8

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薬物溶出性ステント留置例における血小板凝集能と予後

塚原健吾, 木村一雄, 海老名俊明, 小菅雅美, 日比潔, 奥田純, 岩橋徳明, 仲地達哉, 三橋孝之, 大塚文之, 小村直弘, 羽柴克孝, 中山尚貴, 梅村敏

日本心臓病学会誌 2 ( Suppl.I ) 439 - 439 2008.8

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早期再灌流療法に成功した初回ST上昇型急性冠症候群の拡張期弛緩能に関する検討 Tissue Strain Imagingでの検討

岩橋徳明, 羽柴克孝, 奥田純, 海老名俊明, 三橋孝之, 小菅雅美, 小村直弘, 大塚文之, 南一敏, 仲地達哉, 塚原健吾, 田原良雄, 日比潔, 梅村敏, 木村一雄

日本心臓病学会誌 2 ( Suppl.I ) 457 - 457 2008.8

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ST上昇型急性冠症候群における再灌流療法後のIschemic Diastolic Stunningの評価にTSI法を用いたストレインレート法は有効である

岩橋徳明, 小菅雅美, 中山尚貴, 小村直弘, 羽柴克孝, 大塚文之, 仲地達哉, 三橋孝之, 奥田純, 塚原健吾, 日比潔, 田原良雄, 海老名俊明, 梅村敏, 木村一雄

日本心臓病学会誌 2 ( Suppl.I ) 458 - 458 2008.8

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急性前壁梗塞再疎通後の梗塞サイズの予測におけるST-segment elevation resolutionの問題点

奥田純, 小菅雅美, 海老名俊明, 日比潔, 塚原健吾, 岩橋徳明, 仲地達哉, 三橋孝之, 田原良雄, 梅村敏, 木村一雄

日本心臓病学会誌 2 ( Suppl.I ) 473 - 473 2008.8

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非ST上昇型急性冠症候群で急性期に自然経過で腎機能悪化を呈する例の臨床像

仲地達哉, 小菅雅美, 日比潔, 海老名俊明, 塚原健吾, 奥田純, 岩橋徳明, 田原良雄, 梅村敏, 木村一雄

日本心臓病学会誌 2 ( Suppl.I ) 497 - 497 2008.8

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性別および年齢別にみた急性心筋梗塞症の臨床像の違い

小菅雅美, 海老名俊明, 日比潔, 奥田純, 岩橋徳明, 塚原健吾, 三橋孝之, 中山尚貴, 仲地達哉, 木村一雄, 梅村敏

日本心臓病学会誌 2 ( Suppl.I ) 240 - 240 2008.8

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急性心筋梗塞症におけるPCI後のNo-reflowと梗塞サイズ、心機能との関連、およびIVUSでのNo-reflowの予測因子についての検討

遠藤光明, 日比潔, 海老名俊明, 小菅雅美, 塚原健吾, 奥田純, 岩橋徳明, 三橋孝之, 大塚文之, 草間郁好, 小村直弘, 清国雅義, 清水智明, 猿渡力, 梅村敏, 木村一雄

日本心臓病学会誌 2 ( Suppl.I ) 259 - 259 2008.8

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非糖尿病耐糖能異常患者におけるインスリン抵抗性とintegrated backscatter IVUS(IB-IVUS)を用いた冠動脈プラーク組織性状との関係

三橋孝之, 日比潔, 小村直弘, 大塚文之, 南一敏, 羽柴克孝, 仲地達哉, 岩橋徳明, 前島信彦, 奥田純, 塚原健吾, 田原良雄, 小菅雅美, 海老名俊明, 梅村敏, 木村一雄

日本心臓病学会誌 2 ( Suppl.I ) 279 - 279 2008.8

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心肺停止に対するPCPS使用例の予後

田原良雄, 鈴木範行, 小菅宇之, 南一敏, 清國雅義, 中山尚貴, 小村直弘, 羽柴克孝, 大塚文之, 三橋孝之, 仲地達也, 岩橋徳明, 奥田純, 塚原健吾, 日比潔, 小菅雅美, 海老名俊明, 住田晋一, 木村一雄, 梅村敏

循環制御 29 ( Suppl. ) 79 - 79 2008.5

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急性心筋梗塞による院外心肺停止症例に対するPCPSの有用性

田原良雄, 木村一雄, 羽柴克孝, 岩橋徳明, 奥田純, 塚原健吾, 日比潔, 小菅雅美, 海老名俊明, 豊田洋, 小菅宇之, 荒田慎寿, 岩下眞之, 森脇義弘, 鈴木範行

J-ReSS 1 29 - 29 2008.3

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Noninvasive estimation of left ventricular filling pressure by E/e is a powerful predictor of major adverse cardiac and cerebrovascular events in patients with a first ST elevation acute myocardial infarction

Noriaki Iwahashi, Kazuo Kimura, Jun Okuda, Kengo Tsukahara, Yoshio Tahara, Kiyoshi Hibi, Masami Kosuge, Toshiaki Ebina, Shinnichi Sumita, Toshiyuki Ishikawa, Kazuaki Uchino, Satoshi Umemura

JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY 51 ( 10 ) A295 - A295 2008.3

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Real time/live three-dimensional transthoracic echocardiography is a clinically useful diagnostic tool for acute aortic dissection

Noriaki Iwahashi, Kazuo Kimura, Jun Okuda, Kengo Tsukahara, Yoshio Tahara, Kiyoshi Hibi, Masami Kosuge, Toshiaki Ebina, Shinichi Sumita, Toshiyuki Ishikawa, Kazuaki Uchino, Satoshi Umemura

JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY 51 ( 10 ) A313 - A313 2008.3

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Assessment of transmural strain profile using tissue strain imaging is an useful method to evaluate the time course of myocardial stunning in patients with reperfused ST elevation acute coronary syndrome

Noriaki Iwahashi, Kazuo Kimura, Jun Okuda, Kengo Tsukahara, Yoshio Tahara, Kiyoshi Hibi, Masami Kosuge, Toshialki Ebina, Shinichi Sumita, Toshiyuki Ishikawa, Kazuaki Uchmo, Satoshi Umemura

JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY 51 ( 10 ) A253 - A253 2008.3

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急性冠症候群おける明らかな石灰化によらない超音波減衰と冠インターベンション後の造影遅延との関係

遠藤光明, 日比潔, 小村直弘, 大塚文之, 三橋孝之, 岩橋徳明, 奥田純, 塚原健吾, 小菅雅美, 海老名俊明, 木村一雄, 梅村敏

日本冠疾患学会雑誌 13 ( 4 ) 350 - 350 2007.11

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非糖尿病患者におけるインスリン抵抗性とIB-IVUSを用いた冠動脈プラーク組織性状との関係

三橋孝之, 日比潔, 小菅雅美, 海老名俊明, 塚原健吾, 奥田純, 岩橋徳明, 遠藤光明, 大塚文之, 仲地達哉, 草間郁好, 小村直弘, 清國雅義, 木村一雄, 梅村敏

日本冠疾患学会雑誌 13 ( 4 ) 348 - 348 2007.11

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急性心筋梗塞血栓溶解療法施行例における発症前のスタチン投与と再疎通後の心筋傷害との関係

清国雅義, 小菅雅美, 奥田純, 海老名俊明, 日比潔, 塚原健吾, 岩橋徳明, 梅村敏, 木村一雄

日本冠疾患学会雑誌 13 ( 4 ) 349 - 349 2007.11

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Noninvasive estimation of left ventricular filling pressure by E/e' is a powerful predictor of major adverse cardiac and cerebrovascular events in patients with a first ST elevation acute myocardial infarction

Noriaki Iwahashi, Kazuo Kimura, Jun Okuda, Kengo Tsukahara, Kiyoshi Hibi, Masami Kosuge, Toshiaki Ebina, Yoshio Tahara

CIRCULATION 116 ( 16 ) 598 - 598 2007.10

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複数のアテローム血栓症の併存例における血小板凝集能

塚原健吾, 木村一雄, 海老名俊明, 小菅雅美, 日比潔, 奥田純, 岩橋徳明, 梅村敏

日本血栓止血学会誌 18 ( 5 ) 490 - 490 2007.10

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待機的PCIにおける血小板凝集能の検討

塚原健吾, 木村一雄, 海老名俊明, 小菅雅美, 日比潔, 奥田純, 岩橋徳明, 遠藤光明, 仲地達哉, 三橋孝之, 大塚文之, 草間郁好, 小村直弘, 梅村敏

Journal of Cardiology 50 ( Suppl.I ) 561 - 561 2007.8

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早期再灌流療法に成功したST上昇型急性冠症候群における局所ストレインに関する検討

岩橋徳明, 小村直弘, 草間郁好, 大塚文之, 三橋孝之, 仲地達哉, 遠藤光明, 奥田純, 塚原健吾, 田原良雄, 日比潔, 小菅雅美, 海老名俊明, 木村一雄, 梅村敏

Journal of Cardiology 50 ( Suppl.I ) 328 - 328 2007.8

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非糖尿病患者におけるインスリン抵抗性とIntegrated Backscatter IVUS(IB-IVUS)を用いた冠動脈プラーク組織性状との関係

三橋孝之, 日比潔, 小菅雅美, 住田晋一, 海老名俊明, 田原良雄, 塚原健吾, 奥田純, 岩橋徳明, 遠藤光明, 仲地達哉, 大塚文之, 草間郁好, 羽柴克孝, 小村直弘, 南一敏, 清国雅義, 中山尚貴, 木村一雄, 梅村敏

Journal of Cardiology 50 ( Suppl.I ) 271 - 271 2007.8

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急性心筋梗塞症例における、明らかな石灰化によらない超音波減衰と冠動脈インターベンション後の造影遅延の関係

遠藤光明, 日比潔, 海老名俊明, 小菅雅美, 塚原健吾, 奥田純, 岩橋徳明, 仲地達哉, 三橋孝之, 大塚文之, 草間郁好, 羽柴克孝, 小村直之, 南一敏, 清国雅義, 清水智明, 梅村敏, 木村一雄

Journal of Cardiology 50 ( Suppl.I ) 294 - 294 2007.8

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急性心筋梗塞前のスタチン内服は血栓溶解療法施行後の再疎通時間を向上させるか?

清國雅義, 奥田純, 小菅雅美, 住田晋一, 海老名俊明, 日比潔, 田原良雄, 塚原健吾, 岩橋徳明, 遠藤光明, 仲地達哉, 三橋孝之, 大塚文之, 羽柴克孝, 草間郁好, 小村直弘, 南一敏, 中山尚貴, 木村一雄, 梅村敏

Journal of Cardiology 50 ( Suppl.I ) 475 - 475 2007.8

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冠動脈近位部と遠位部でプラーク組織性状は異なるか? Integrated backscatter intravascular ultrasound(IB-IVUS)を用いた検討

小村直弘, 日比潔, 清国雅義, 南一敏, 羽柴克孝, 草間郁好, 大塚文之, 三橋孝之, 仲地達哉, 遠藤光明, 岩橋徳明, 奥田純, 塚原健吾, 小菅雅美, 住田晋一, 海老名俊明, 木村一雄, 梅村敏

Journal of Cardiology 50 ( Suppl.I ) 555 - 555 2007.8

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不安定狭心症の急性期に一過性肝障害を呈する症例の臨床像

仲地達哉, 小菅雅美, 海老名俊明, 住田晋一, 日比潔, 塚原健吾, 奥田純, 田原良雄, 岩橋徳明, 木村一雄, 梅村敏

Journal of Cardiology 50 ( Suppl.I ) 557 - 557 2007.8

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角度補正組織ストレインドプラー法によるST上昇型急性冠症候群における局所心筋障害の評価 99mTc-MIBIとの対照研究

岩橋徳明, 木村一雄, 遠藤光明, 三橋孝之, 小村直弘, 草間郁好, 大塚文之, 仲地達哉, 奥田純, 小菅雅美, 塚原健吾, 田原良雄, 日比潔, 海老名俊明, 梅村敏, 望月秀一, 石川栄二

Journal of Cardiology 50 ( Suppl.I ) 328 - 328 2007.8

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トロポニン陰性の非ST上昇型急性冠症候群におけるD-dimer上昇の意義

塚原健吾, 木村一雄, 海老名俊明, 小菅雅美, 日比潔, 奥田純, 岩橋徳明, 遠藤光明, 仲地達哉, 三橋孝之, 大塚文之, 草間郁好, 小村直弘, 梅村敏

Journal of Cardiology 50 ( Suppl.I ) 339 - 339 2007.8

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急性下壁梗塞におけるV5-6誘導のST上昇の臨床的意義

小菅雅美, 海老名俊明, 日比潔, 塚原健吾, 岩橋徳明, 奥田純, 遠藤光明, 大塚文之, 三橋孝之, 羽柴克孝, 仲地達哉, 木村一雄, 梅村敏

Journal of Cardiology 50 ( Suppl.I ) 405 - 405 2007.8

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前胸部誘導で陰性T波を認める急性肺塞栓と急性冠症候群の鑑別

小菅雅美, 海老名俊明, 日比潔, 奥田純, 岩橋徳明, 塚原健吾, 遠藤光明, 仲地達哉, 大塚文之, 小村直弘, 木村一雄, 梅村敏

Journal of Cardiology 50 ( Suppl.I ) 406 - 406 2007.8

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非ST上昇型急性冠症候群における入院24時間後のC反応性蛋白測定の臨床的意義

小菅雅美, 海老名俊明, 日比潔, 奥田純, 岩橋徳明, 塚原健吾, 三橋孝之, 遠藤光明, 羽柴克孝, 田原良雄, 草間郁好, 木村一雄, 梅村敏

Journal of Cardiology 50 ( Suppl.I ) 454 - 454 2007.8

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Real time経胸壁3D心エコーによる急性大動脈解離の診断

岩橋徳明, 遠藤光明, 奥田純, 海老名俊明, 三橋孝之, 小菅雅美, 小村直弘, 草間郁好, 大塚文之, 仲地達哉, 塚原健吾, 田原良雄, 日比潔, 梅村敏, 木村一雄

Journal of Cardiology 50 ( Suppl.I ) 472 - 472 2007.8

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初回ST上昇型急性冠症候群においてE/e'は一年以内の再入院の予測因子である

岩橋徳明, 木村一雄, 小村直弘, 草間郁好, 大塚文之, 仲地達哉, 三橋孝之, 遠藤光明, 奥田純, 塚原健吾, 日比潔, 小菅雅美, 田原良雄, 海老名俊明, 梅村敏

Journal of Cardiology 50 ( Suppl.I ) 473 - 473 2007.8

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Language：Japanese Publisher：(一社)日本心臓病学会

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急性心筋梗塞症に対するステント留置時のステント径と微小循環障害の関係

奥田純, 小菅雅美, 海老名俊明, 住田晋一, 日比潔, 田原良雄, 塚原健吾, 岩橋徳明, 木村一雄, 梅村敏

Journal of Cardiology 50 ( Suppl.I ) 474 - 474 2007.8

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血管内超音波によるSirolimus-eluting stent留置後の慢性期ステント圧着不良についての検討 Bare metal stentとの比較

遠藤光明, 日比潔, 海老名俊明, 小菅雅美, 塚原健吾, 奥田純, 岩橋徳明, 仲地達哉, 三橋孝之, 大塚文之, 草間郁好, 羽柴克孝, 小村直弘, 南一敏, 清国雅義, 梅村敏, 木村一雄

Journal of Cardiology 50 ( Suppl.I ) 313 - 313 2007.8

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Effects of Angiotensin-II receptor blockers on coronary atherosclerosis in patients with acute myocardial infarction taking angiotensin-converting-enzyme inhibitors: Final results of captopril combined with valsartan in acute myocardial infarction study (CVAS)

Hideto Yano, Kiyoshi Hibi, Hiroyuki Ozaki, Ikuyoshi Kusama, Mitsuaki Endou, Takayuki Mitsuhashi, Naohiro Komura, Toshiaki Ebina, Masami Kosuge, Kengo Tsukahara, Jun Okuda, Noriaki Iwahashi, Tatsuya Nakachi, Fumiyuki Otsuka, Satoshi Umemura, Kazuo Kimura

JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY 49 ( 9 ) 316A - 316A 2007.3

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Web of Science

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A full recovery case from sudden cardiac arresi with an automated external defibrillator placed in a sports center

Nakayama Naoki, Nakachi Tatsuya, Endo Mitsuaki, Mitsuhashi Takayuki, Otsuka Fumiyuki, Kusama Ikuyoshi, Komura Naohiro, Kimura Kazuo, Hashiba Katsutaka, Tahara Yoshio, Kosuge Takayuki, Ozaki Hiroyuki, Sugiyama Mitsugi, Ebina Toshiaki, Kosuge Masami, Hibi Kiyoshi, Tsukahara Kengo, Okuda Jun, Iwahashi Noriaki, Yano Hideto

Shinzo 39 ( 3 ) 54 - 57 2007

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DOI： 10.11281/shinzo1969.39.Supplement3_54

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Acute improvement in myocardial function assessed by myocardial strain and strain rate after aortic valve replacement for aortic stenosis

Noriaki Iwahashi, Satoshi Nakatani, Hideaki Kanzaki, Takuya Hasegawa, Haruhiko Abe, Masafumi Kitakaze

JOURNAL OF THE AMERICAN SOCIETY OF ECHOCARDIOGRAPHY 19 ( 10 ) 1238 - 1244 2006.10

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DOI： 10.1016/j.echo.2006.04.041

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急性肺動脈血栓塞栓症のリスク層別における陰性T波の臨床的意義

小菅雅美, 海老名俊明, 日比潔, 塚原健吾, 奥田純, 岩橋徳明, 仲地達哉, 大塚文之, 三橋孝之, 小村直弘, 田原良雄, 矢野英人, 尾崎弘幸, 羽柴克孝, 木村一雄, 梅村敏

Journal of Cardiology 48 ( Suppl.I ) 663 - 663 2006.9

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急性前壁心筋梗塞症におけるST上昇の経時的変化の意義

奥田純, 木村一雄, 小菅雅美, 海老名俊明, 日比潔, 塚原健吾, 田原良雄, 岩橋徳明, 羽柴克孝, 梅村敏

Journal of Cardiology 48 ( Suppl.I ) 671 - 671 2006.9

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急性心筋梗塞患者におけるメタボリック症候群の臨床像

小菅雅美, 海老名俊明, 日比潔, 塚原健吾, 奥田純, 岩橋徳明, 遠藤光明, 仲地達哉, 大塚文之, 三橋孝之, 小村直弘, 矢野英人, 尾崎弘幸, 草間郁好, 木村一雄, 梅村敏

Journal of Cardiology 48 ( Suppl.I ) 705 - 705 2006.9

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早期再灌流療法に成功したST上昇型急性心筋梗塞症例におけるストレインに関する検討

岩橋徳明, 木村一雄, 仲地達哉, 矢野英人, 奥田純, 塚原健吾, 日比潔, 小菅雅美, 田原良雄, 海老名俊明, 梅村敏

Journal of Cardiology 48 ( Suppl.I ) 429 - 429 2006.9

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不安定狭心症患者における非責任病変の冠動脈病変形態と動脈硬化進展との関係

仲地達哉, 小菅雅美, 海老名俊明, 住田晋一, 日比潔, 塚原健吾, 奥田純, 岩橋徳明, 田原良男, 木村一雄, 梅村敏

Journal of Cardiology 48 ( Suppl.I ) 631 - 631 2006.9

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多発複雑病変を有する症例における非責任中等度病変の進行

岩橋徳明, 木村一雄, 草間育好, 尾崎弘幸, 奥田純, 塚原健吾, 日比潔, 小菅雅美, 海老名俊明, 田原良雄, 梅村敏

Journal of Cardiology 48 ( Suppl.I ) 633 - 633 2006.9

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Plaque Ruptureの位置に冠リモデリングは影響するか? 血管内超音波を用いた検討

草間郁好, 日比潔, 尾崎弘幸, 矢野英人, 海老名俊明, 小菅雅美, 塚原健吾, 奥田純, 岩橋徳明, 遠藤光明, 仲地達哉, 三橋孝之, 大塚文之, 小村直弘, 梅村敏, 木村一雄

Journal of Cardiology 48 ( Suppl.I ) 428 - 428 2006.9

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不安定狭心症患者におけるCRP上昇と非責任病変の冠動脈硬化進展との関係

仲地達哉, 小菅雅美, 海老名俊明, 住田晋一, 日比潔, 塚原健吾, 奥田純, 田原良男, 岩橋徳明, 木村一雄, 梅村敏

Journal of Cardiology 48 ( Suppl.I ) 310 - 310 2006.9

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Impact of plaque rupture on myocardial infarct size in ST-elevation anterior acute myocardial infarction

Kusama, I, K Hibi, M Kosuge, N Nozawa, H Ozaki, H Yano, T Ebina, S Sumita, M Kanna, K Tsukahara, J Okuda, N Iwahashi, T Nakachi, Y Tahara, S Umemura, K Kimura

JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY 47 ( 4 ) 212A - 212A 2006.2

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非ST上昇型急性冠症候群における退院後の心事故予測因子の検討

田原良雄, 木村一雄, 小菅雅美, 海老名俊明, 日比潔, 漢那雅彦, 塚原健吾, 奥田純, 野沢直樹, 岩橋徳明, 尾崎弘幸, 矢野英人, 仲地達哉, 羽柴克孝, 杉山貢

日本冠疾患学会雑誌 11 ( 4 ) 275 - 275 2005.11

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ST上昇型急性下壁梗塞におけるaVR誘導のST低下の臨床的意義

小菅雅美, 木村一雄, 海老名俊明, 日比潔, 漢那雅彦, 塚原健吾, 奥田純, 野澤直樹, 岩橋徳明, 矢野英人, 尾崎弘幸, 仲地達哉, 草間郁好, 梅村敏

日本冠疾患学会雑誌 11 ( 4 ) 274 - 274 2005.11

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大動脈弁狭窄症におけるBNP測定の意義

岩橋徳明, 中谷敏, 神崎秀明, 金智隆, 花谷彰久, 橋村一彦, 山岸正和, 北風政史

Journal of Cardiology 44 ( Suppl.I ) 353 - 353 2004.8

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高度の無動を呈するparkinsonism患者にみられた圧迫性腕神経叢障害 Reviewed

岩橋徳明, 薄敬一郎, 松本麻理, 城倉健, 小宮山純

神経内科、vol49 No1 1998

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血行再建を伴わないCTEPHに対する肺血管拡張薬の効果を再考する:当院でのSelexipagとRiociguatの肺血行動態への効果の比較検討

小村直弘, 菅野晃靖, 鈴木徹, 小西正紹, 岩橋徳明, 石上友章, 日比潔

日本心臓病学会学術集会(Web) 72nd 2024

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バルサルバ洞動脈瘤が塞栓源と考えられた若年発症の血栓性急性心筋梗塞の1例

山内健輔, 鈴木徹, 石井怜, 乙竹泰, 相澤広太郎, 阿部茉莉愛, 菅原拓哉, 中島理恵, 小村直弘, 川浦範之, 小西正紹, 岩橋徳明, 石上友章, 山口由衣, 日比潔

日本心臓病学会学術集会(Web) 72nd 2024

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Clinical Utility of Machine Learning-Derived Vocal-Biomarker in the Management of Heart Failure

Kozo Okada, Yasuhiro Omiya, Daisuke Mizuguchi, Koji Endo, Yusuke Kobayashi, Yasushi Matsuzawa, Noriaki Iwahashi, Masami Kosuge, Toshiaki Ebina, Kouichi Tamura, Kiyoshi Hibi

CIRCULATION 146 2022.11

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なにそれ,どうする?教科書ではわからないギモンに迫る MINOCAとINOCAに心エコーでせまる

岩橋徳明

心エコー 23 ( 9 ) 2022

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Impressively Reported Cases(77)Transcatheter Aortic Valve Implantation (TAVI) in a Patient with Severe Aortic Stenosis and Left Ventricular Outflow Tract Obstruction

42 ( 8 ) 542 - 546 2018.8

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CiNii Books

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Other Link： http://search.jamas.or.jp/link/ui/2019029384
術後慢性期に血栓弁となったTAVIの一例

桐ヶ谷仁, 岩橋徳明, 松澤泰志, 岡田興造, 小西正昭, 前島信彦, 小菅雅美, 日比潔, 木村一雄, 田村功一

超音波医学 45 ( Suppl. ) S622 - S622 2018.4

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Glycemic Variability at Acute Phase can Predict Left Ventricle Remodeling in Patients with STEMI(和訳中)

高橋広軌, 岩橋徳明, 南本祐吾, 桐ケ谷仁, 木村裕一郎, 松澤泰志, 小西正紹, 前島信彦, 日比潔, 小菅雅美, 海老名俊明, 田村功一, 木村一雄

日本循環器学会学術集会抄録集 82回 PJ002 - 6 2018.3

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Skeletal Muscle-targeted Strategy for Heart Failure Prevention in Elderly, Frail Patients after ST-elevation Myocardial Infarction(和訳中)

小西正紹, 松澤泰志, 秋山英一, 木村裕一郎, 前島信彦, 岩橋徳明, 日比潔, 小菅雅美, 海老名俊明, 木村一雄, 田村功一

日本循環器学会学術集会抄録集 82回 PL8 - 6 2018.3

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No ST-Segment Elevation Resolution in Lead aVR Strongly Predicts 1-Year Adverse Outcomes in Patients with Non-ST-Segment Elevation Acute Coronary Syndrome(和訳中)

小菅雅美, 日比潔, 岩橋徳明, 前島信彦, 松澤泰志, 小西正紹, 海老名俊明, 木村裕一郎, 田村功一, 木村一雄

日本循環器学会学術集会抄録集 82回 OJ16 - 1 2018.3

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ST-Segment Depression in Lead aVR Predicts 30-day Adverse Outcomes in Patients with Inferior Acute Myocardial Infarction(和訳中)

小菅雅美, 日比潔, 岩橋徳明, 前島信彦, 松澤泰志, 小西正紹, 海老名俊明, 木村裕一郎, 田村功一, 木村一雄

日本循環器学会学術集会抄録集 82回 ( 13 ) OJ16 - 2 2018.3

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DOI： 10.1016/S0735-1097(16)30476-4

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The Increase in Trimethylamine N-oxide is Associated with the Progression of Coronary Plaque Complexity in Patients with Acute Myocardial Infarction(和訳中)

中橋秀文, 松澤泰志, 日比潔, 岩橋徳明, 前島信彦, 小西正紹, 木村裕一郎, 小菅雅美, 田村功一, 木村一雄

日本循環器学会学術集会抄録集 82回 OJ16 - 6 2018.3

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ST上昇型急性心筋梗塞患者における四肢骨格筋量の予後への影響

佐藤亮佑, 松澤泰志, 秋山英一, 小西正昭, 前島信彦, 岩橋徳明, 小菅雅美, 日比潔, 木村一雄, 田村功一

日本冠疾患学会雑誌 ( Suppl. ) 159 - 159 2017.12

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急性心筋梗塞患者における腸内細菌由来Trimethylamine-N-oxide変化と冠動脈病変の重症度変化との関係

中橋秀文, 松澤泰志, 日比潔, 岩橋徳明, 前島信彦, 小西正紹, 木村裕一郎, 小菅雅美, 木村一雄, 田村功一

日本冠疾患学会雑誌 ( Suppl. ) 139 - 139 2017.12

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The Change in Gut Microbiota-Dependent Trimethylamine N-oxide Between Acute and Chronic Phase Related to the Progression of Coronary Plaque Complexity in Patients With Acute Myocardial Infarction

Hidefumi Nakahashi, Yasushi Matsuzawa, Toshiaki Ebina, Kiyoshi Hibi, Noriaki Iwahashi, Nobuhiko Maejima, Masaaki Konishi, Yuichirou Kimura, Naoki Nakayama, Masami Kosuge, Kazuo Kimura, Kouichi Tamura

CIRCULATION 136 2017.11

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左室収縮の保たれた心不全における骨格筋量・脂肪量が予後に与える影響

小西正紹, 秋山英一, 松澤泰志, 佐藤亮祐, 木村裕一郎, 前島信彦, 岩橋徳明, 日比潔, 木村一雄, 田村功一

日本サルコペニア・フレイル学会雑誌 1 ( 2 ) 152 - 152 2017.10

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急性心筋梗塞緊急冠動脈ステント留置例における来院時腎機能が急性腎障害と院内予後との関係に及ぼす影響

中橋秀文, 小菅雅美, 清國雅義, 海老名俊明, 日比潔, 岩橋徳明, 前島信彦, 小西正紹, 松澤泰志, 木村裕一郎, 田村功一, 木村一雄

日本心臓病学会学術集会抄録 65回 P - 029 2017.9

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持続血糖測定器(CGM)により測定される血糖変動(MAGE)

岩橋徳明, 高橋広軌, 桐ヶ谷仁, 南本祐吾, 木村裕一郎, 松澤泰志, 小西正紹, 前島信彦, 日比潔, 小菅雅美, 海老名俊明, 木村一雄, 田村功一

日本心臓病学会学術集会抄録 65回 SS10 - 5 2017.9

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心不全と合併疾患対策心臓悪液質・サルコペニアと栄養・貧血体液シフトの観点から

小西正紹, 秋山英一, 佐藤亮佑, 川島千佳, 松澤泰志, 木村裕一郎, 前島信彦, 岩橋徳明, 日比潔, 小菅雅美, 海老名俊明, 木村一雄, 田村功一

日本心臓病学会学術集会抄録 65回 PD3 - 4 2017.9

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血糖変動はST上昇型急性前壁心筋梗塞患者における左室リモデリングおよび左室リバースリモデリングに影響を与える

南本祐吾, 岩橋徳明, 桐ヶ谷仁, 高橋広軌, 松澤泰志, 前島信彦, 日比潔, 小菅雅美, 海老名俊明, 木村一雄, 田村功一

日本心臓病学会学術集会抄録 65回 O - 161 2017.9

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3枝病変を有する前壁STEMIに対するLADのPCI後に亜急性ステント血栓症を起こし、心不全加療難渋のためCABGを施行した1例

菊地進之介, 木村裕一郎, 松澤泰志, 小西正紹, 前島信彦, 岩橋徳明, 日比潔, 小菅雅美, 海老名俊明, 木村一雄, 田村功一

日本心臓病学会学術集会抄録 65回 P - 013 2017.9

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非ST上昇型急性冠症候群と動脈スティフネスの関連性

桐ヶ谷仁, 岩橋徳明, 松澤泰志, 小西正紹, 前島信彦, 日比潔, 小菅雅美, 海老名俊明, 木村一雄, 田村功一

日本心臓病学会学術集会抄録 65回 P - 015 2017.9

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ST上昇型急性心筋梗塞に対するprimary PCIと非ST上昇型急性冠症候群/安定虚血性心疾患に対するelective PCIにおける血栓性の評価

菊地進之介, 塚原健吾, 市川晋也, 木村裕一郎, 松澤泰志, 前島信彦, 岩橋徳明, 日比潔, 小菅雅美, 海老名俊明, 木村一雄, 田村功一

日本心血管インターベンション治療学会抄録集 26回 MO462 - MO462 2017.7

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血糖変動はST部分上昇型前壁心筋梗塞既往患者の右室全体機能と関連している UCGストレイン解析(Glycemic Variability is Associated with Right Ventricular Global Function in Patients with Anterior ST-segment Elevation Myocardial Infarction: UCG Strain Analysis)

片岡俊介, 岩橋徳明, 前島信彦, 日比潔, 小菅雅美, 海老名俊明, 木村一雄, 田村功一

日本循環器学会学術集会抄録集 81回 PJ - 755 2017.3

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急性心筋梗塞患者において赤血球分布幅の変化が長期転帰に及ぼす影響(Impact of Change in Red Cell Distribution Width on Long-term Outcomes in Patients with Acute Myocardical Infarction)

中橋秀文, 小菅雅美, 清國雅義, 海老名俊明, 日比潔, 岩橋徳明, 前島信彦, 小西正紹, 松澤泰志, 木村裕一郎, 木村一雄, 田村功一

日本循環器学会学術集会抄録集 81回 OJ - 105 2017.3

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たこつぼ心筋症と再灌流された非Q波前壁急性心筋梗塞間の鑑別のための簡単な心電図判定基準(Simple Electrocardiographic Criteria for Discriminating between Takotsubo Cardiomyopathy and Reperfused Non-Q Wave Anterior Acute Myocardial Infarction)

小菅雅美, 海老名俊明, 日比潔, 岩橋徳明, 前島信彦, 松澤泰志, 木村裕一郎, 木村一雄, 田村功一

日本循環器学会学術集会抄録集 81回 ( 13 ) OJ - 141 2017.3

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DOI： 10.1016/S0735-1097(16)30528-9

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A型急性大動脈解離患者においてaVR誘導でのST上昇は30日死亡率に関する最強の予測因子である(ST-Segment Elevation in Lead aVR is the Strongest Predictor of 30-Day Mortality in Patients with Type A Acute Aortic Dissection)

小菅雅美, 内田敬二, 海老名俊明, 日比潔, 岩橋徳明, 前島信彦, 松澤泰志, 木村裕一郎, 益田宗孝, 木村一雄, 田村功一

日本循環器学会学術集会抄録集 81回 OJ - 142 2017.3

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初回ST上昇型心筋梗塞の血管スティフネスおよびLV充満圧と相関する血糖変動(Glycemic Variability Correlated with Vascular Stiffness and LV Filling Pressure of First STsegment Elevation Myocardial Infarction)

桐ヶ谷仁, 岩橋徳明, 松澤泰志, 前島信彦, 日比潔, 小菅雅美, 海老名俊明, 木村一雄, 田村功一

日本循環器学会学術集会抄録集 81回 OJ - 184 2017.3

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高インスリン血症/insulin抵抗性は、梗塞サイズが比較的小さくても初発STEMI患者の左室リモデリングの原因となる(Hyperinsulinemia/Insulin Resistance Causes Left Ventricular Remodeling in Patients with a First STEMI despite Having Smaller Infarction)

岩橋徳明, 桐ヶ谷仁, 南本祐吾, 片岡俊介, 高橋広軌, 木村裕一郎, 松澤泰志, 前島信彦, 日比潔, 小菅雅美, 海老名俊明, 木村一雄, 田村功一

日本循環器学会学術集会抄録集 81回 PJ - 105 2017.3

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ST部分上昇型心筋梗塞の発症後急性期の3Dスペックルトラッキングストレインで推定したtwisting motionの臨床有用性 Tc99m-sestamibiとの比較(Clinical Usefulness of Twisting Motion Estimated by 3D-Speckle Tracking Strain Acutely after Onset of ST-Elevation Myocardial Infarction: Comparison with Tc99m-sestamibi)

岩橋徳明, 南本祐吾, 高橋広軌, 桐ヶ谷仁, 木村裕一郎, 松澤泰志, 前島信彦, 日比潔, 小菅雅美, 海老名俊明, 木村一雄, 田村功一

日本循環器学会学術集会抄録集 81回 PJ - 117 2017.3

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急性肺塞栓症と急性冠症候群を鑑別する簡便な心電図判定基準(Simple Electrocardiographic Criteria for Discriminating between Acute Pulmonary Embolism and Acute Coronary Syndrome)

小菅雅美, 海老名俊明, 日比潔, 岩橋徳明, 前島信彦, 松澤泰志, 木村裕一郎, 木村一雄, 田村功一

日本循環器学会学術集会抄録集 81回 ( 13 ) PJ - 198 2017.3

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DOI： 10.1016/S0735-1097(16)30529-0

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冠動脈疾患患者における石灰化結節の発現率、予測因子、および形態血管内光干渉断層撮影(Incidence, Predictors, and Morphology of Calcified Nodule in Patients with Coronary Artery Disease: An Intravascular Optical Coherence Tomography)

久慈正太郎, 日比潔, 前島信彦, 木村裕一郎, 松澤泰志, 岩橋徳明, 小菅雅美, 海老名俊明, 住田晋一, 木村一雄, 田村功一

日本循環器学会学術集会抄録集 81回 PJ - 433 2017.3

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急性心不全患者の四肢骨格筋量の予後的影響における性差(Gender Differences in Prognostic Impact of Appendicular Skeletal Muscle Mass in Patients with Acute Heart Failure)

秋山英一, 小西正紹, 松澤泰志, 佐藤亮佑, 川島千佳, 鈴木弘之, 前島信彦, 岩橋徳明, 塚原健吾, 日比潔, 小菅雅美, 海老名俊明, 木村一雄, 田村功一

日本循環器学会学術集会抄録集 81回 PJ - 686 2017.3

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急性心筋梗塞患者において貧血と赤血球分布幅が長期転帰に及ぼす複合的影響(Combined Impact of Anemia and Red Cell Distribution Width on Long-term Outcomes in Patients with Acute Myocardial Infarction)

中橋秀文, 小菅雅美, 清國雅義, 海老名俊明, 日比潔, 岩橋徳明, 前島信彦, 小西正紹, 松澤泰志, 木村裕一郎, 木村一雄, 田村功一

日本循環器学会学術集会抄録集 81回 PJ - 710 2017.3

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血糖変動によりST上昇型心筋梗塞患者のLV機能が予測可能である MRIストレイン解析(Glycemic Variability can Predict LV Function in Patients with ST-elevation Myocardial Infarction: MRI Strain Analysis)

高橋広軌, 岩橋徳明, 片岡俊介, 松澤泰志, 前島信彦, 日比潔, 小菅雅美, 海老名俊明, 木村一雄, 田村功一

日本循環器学会学術集会抄録集 81回 PJ - 754 2017.3

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The Combination of Dyssynchrony and Global Longitudinal Strain by 3D Speckle Tracking After ST-Elevation Myocardial Infarction is an Useful Predictor

Noriaki Iwahashi, Hironori Takahashi, Yasushi Matsuzawa, Nobuhiko Maejima, Kiyoshi Hibi, Masami Kosuge, Toshiaki Ebina, Kazuo Kimura

CIRCULATION 134 2016.11

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Frailty as Assessed by Gait Speed is Associated With Peripheral Endothelial Dysfunction in Older Patients With ST-segment Elevation Myocardial Infarction

Ryosuke Satou, Yasushi Matsuzawa, Eiichi Akiyama, Hiroyuki Suzuki, Chika Kawashima, Masaaki Konishi, Katsutaka Hashiba, Nobuhiko Maejima, Noriaki Iwahashi, Kiyoshi Hibi, Masami Kosuge, Toshiaki Ebina, Shinichi Sumita, Kazuo Kimura, Yuuichiro Kimura

CIRCULATION 134 2016.11

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ST-Segment Elevation in Lead aVR Strongly Predicts In-hospital Mortality in Patients With Type A Acute Aortic Dissection

Masami Kosuge, Keiji Uchida, Norihisa Karube, Toshiaki Ebina, Kiyoshi Hibi, Noriaki Iwahashi, Nobuhiko Maejima, Yasushi Matsuzawa, Munetaka Masuda, Kazuo Kimura

CIRCULATION 134 2016.11

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Comparison between Instantaneous Wave-Free Ratio and Fractional Flow Reserve versus Morphometric Assessments by Intracoronary Imaging Devices

Kensuke Matsushita, Kiyoshi Hibi, Kozo Okada, Yasushi Matsuzawa, Yuichiro Kimura, Nobuhiko Maejima, Noriaki Iwahashi, Anton Moritz, Toshiaki Ebina, Peter J. Fitzgerald, Yasuhiro Honda, Kazuo Kimura

JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY 68 ( 18 ) B218 - B218 2016.11

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DOI： 10.1016/j.jacc.2016.09.676

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No ST-Segment Elevation Resolution in Lead aVR Strongly Predicts In-hospital Adverse Outcomes in Patients With Non-ST-Segment Elevation Acute Coronary Syndrome

Masami Kosuge, Toshiaki Ebina, Kiyoshi Hibi, Noriaki Iwahashi, Nobuhiko Maejima, Yasushi Matsuzawa, Kazuo Kimura

CIRCULATION 134 2016.11

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Frailty as Assessed by Gait Speed is Associated With Peripheral Endothelial Dysfunction in Older Patients With ST-segment Elevation Myocardial Infarction

Ryosuke Satou, Yasushi Matsuzawa, Eiichi Akiyama, Hiroyuki Suzuki, Chika Kawashima, Masaaki Konishi, Katsutaka Hashiba, Nobuhiko Maejima, Noriaki Iwahashi, Kiyoshi Hibi, Masami Kosuge, Toshiaki Ebina, Shinichi Sumita, Kazuo Kimura, Yuuichiro Kimura

CIRCULATION 134 2016.11

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Ubiquinol Improves Endothelial Function in Patients With Heart Failure With Reduced Ejection Fraction: A Single Center, Randomized Double-Blind Placebo-Controlled Cross-Over Study

Chika Kawashima, Yasushi Matsuzawa, Eiichi Akiyama, Ryosuke Sato, Masaaki Konishi, Hiroyuki Suzuki, Yuichiro Kimura, Toshiaki Ebina, Masami Kosuge, Kiyoshi Hibi, Noriaki Iwahashi, Nobuhiko Maejima, Kazuo Kimura

CIRCULATION 134 2016.11

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Differences in ST-T Changes Between Takotsubo Cardiomyopathy and Reperfused Non-Q-Wave Anterior Acute Myocardial Infarction

Masami Kosuge, Toshiaki Ebina, Kiyoshi Hibi, Noriaki Iwahashi, Nobuhiko Maejima, Yasushi Matsuzawa, Kazuo Kimura

CIRCULATION 134 2016.11

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No ST-Segment Elevation Resolution in Lead aVR Strongly Predicts In-hospital Adverse Outcomes in Patients With Non-ST-Segment Elevation Acute Coronary Syndrome

Masami Kosuge, Toshiaki Ebina, Kiyoshi Hibi, Noriaki Iwahashi, Nobuhiko Maejima, Yasushi Matsuzawa, Kazuo Kimura

CIRCULATION 134 2016.11

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Low Skeletal Muscle Mass Index is Associated With Cardiovascular Events in Patients After ST-segment Elevation Myocardial Infarction

Ryosuke Satou, Yasushi Matsuzawa, Eiichi Akiyama, Hiroyuki Suzuki, Chika Kawashima, Masaaki Konishi, Yuuichiro Kimura, Katsutaka Hashiba, Nobuhiko Maejima, Noriaki Iwahashi, Kiyoshi Hibi, Masami Kosuge, Toshiaki Ebina, Shinichi Sumita, Kazuo Kimura

CIRCULATION 134 2016.11

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Clinical characteristics of patients with discordant results for fractional flow reserve and instantaneous wave-flow ratio

Kensuke Matsushita, Kiyoshi Hibi, Yasushi Matsuzawa, Yuichiro Kimura, Nobuhiko Maejima, Noriaki Iwahashi, Anton Moritz, Toshiaki Ebina, Kazuo Kimura

JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY 68 ( 18 ) B217 - B217 2016.11

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DOI： 10.1016/j.jacc.2016.09.675

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ST-Segment Elevation in Lead aVR Strongly Predicts In-hospital Mortality in Patients With Type A Acute Aortic Dissection

Masami Kosuge, Keiji Uchida, Norihisa Karube, Toshiaki Ebina, Kiyoshi Hibi, Noriaki Iwahashi, Nobuhiko Maejima, Yasushi Matsuzawa, Munetaka Masuda, Kazuo Kimura

CIRCULATION 134 2016.11

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Differences in ST-T Changes Between Takotsubo Cardiomyopathy and Reperfused Non-Q-Wave Anterior Acute Myocardial Infarction

Masami Kosuge, Toshiaki Ebina, Kiyoshi Hibi, Noriaki Iwahashi, Nobuhiko Maejima, Yasushi Matsuzawa, Kazuo Kimura

CIRCULATION 134 2016.11

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Low Skeletal Muscle Mass Index is Associated With Cardiovascular Events in Patients After ST-segment Elevation Myocardial Infarction

Ryosuke Satou, Yasushi Matsuzawa, Eiichi Akiyama, Hiroyuki Suzuki, Chika Kawashima, Masaaki Konishi, Yuuichiro Kimura, Katsutaka Hashiba, Nobuhiko Maejima, Noriaki Iwahashi, Kiyoshi Hibi, Masami Kosuge, Toshiaki Ebina, Shinichi Sumita, Kazuo Kimura

CIRCULATION 134 2016.11

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Ubiquinol Improves Endothelial Function in Patients With Heart Failure With Reduced Ejection Fraction: A Single Center, Randomized Double-Blind Placebo-Controlled Cross-Over Study

Chika Kawashima, Yasushi Matsuzawa, Eiichi Akiyama, Ryosuke Sato, Masaaki Konishi, Hiroyuki Suzuki, Yuichiro Kimura, Toshiaki Ebina, Masami Kosuge, Kiyoshi Hibi, Noriaki Iwahashi, Nobuhiko Maejima, Kazuo Kimura

CIRCULATION 134 2016.11

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Glycemic Variability is Associated with Left Ventricular Global Systolic Function in Patients with Anterior ST-Segment Elevation Myocardial Infarction

Shunsuke Kataoka, Noriaki Iwahashi, Kazuo Kimura

JOURNAL OF CARDIAC FAILURE 22 ( 9 ) S173 - S173 2016.9

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DOI： 10.1016/j.cardfail.2016.07.113

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Symptomatic heart disease (SHD) caused by radiotherapy for esophageal cancer

61 ( 9 ) 1105 - 1113 2016.9

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Pericardial Fat Loss in Heart Failure With Reduced Ejection Fraction

Masaaki Konishi, Eiichi Akiyama, Noriaki Iwahashi, Toshiaki Ebina, Kazuo Kimura

JOURNAL OF CARDIAC FAILURE 22 ( 9 ) S219 - S219 2016.9

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DOI： 10.1016/j.cardfail.2016.07.348

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Glycemic variability predicts left ventricular reverse remodeling in patients with ST-segment elevation acute myocardial infarction

Y. Minamimoto, N. Iwahashi, M. Gohbara, S. Kataoka, E. Akiyama, Y. Matsuzawa, N. Maejima, K. Tsukahara, K. Hibi, M. Kosuge, T. Ebina, K. Kimura

EUROPEAN HEART JOURNAL 37 925 - 925 2016.8

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Glycemic variability is associated with left ventricular global systolic function in patients with anterior ST-segment elevation myocardial infarction

S. Kataoka, N. Iwahashi, M. Gohbara, E. Akiyama, N. Maejima, K. Tsukahara, K. Hibi, M. Kosuge, T. Ebina, K. Kimura

EUROPEAN HEART JOURNAL 37 928 - 928 2016.8

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BLEEDING RISK STRATIFICATION USING MICROCHIP FLOW-CHAMBER SYSTEM IN PATIENTS RECEIVING MULTIPLE ANTITHROMBOTIC AGENTS

Shinya Ichikawa, Kengo Tsukahara, Eiichi Akiyama, Nobuhiko Maejima, Noriaki Iwahashi, Kiyoshi Hibi, Masami Kosuge, Toshiaki Ebina, Satoshi Umemura, Kazuo Kimura

JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY 67 ( 13 ) 2101 - 2101 2016.4

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DOI： 10.1016/S0735-1097(16)32102-7

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GLYCEMIC VARIABILITY PREDICTS LEFT VENTRICULAR REVERSE REMODELING IN PATIENTS WITH ST-SEGMENT ELEVATION ACUTE MYOCARDIAL INFARCTION

Yugo Minamimoto, Noriaki Iwahashi, Masaomi Gohbara, Shunsuke Kataoka, Eiichi Akiyama, Nobuhiko Maejima, Kengo Tsukahara, Kiyoshi Hibi, Masami Kosuge, Toshiaki Ebina, Satoshi Umemura, Kazuo Kimura

JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY 67 ( 13 ) 490 - 490 2016.4

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DOI： 10.1016/S0735-1097(16)30491-0

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URINARY ALBUMIN EXCRETION PREDICTS RAPID PROGRESSION OF CORONARY ARTERY DISEASE IN PATIENTS WITH ACUTE CORONARY SYNDROME

Shunsuke Kataoka, Noriaki Iwahashi, Masaomi Gohbara, Eiichi Akiyama, Nobuhiko Maejima, Kengo Tsukahara, Kiyoshi Hibi, Masami Kosuge, Kazuo Kimura, Satoshi Umemura

JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY 67 ( 13 ) 494 - 494 2016.4

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DOI： 10.1016/S0735-1097(16)30495-8

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RELATIONSHIP BETWEEN THICKNESS OF CALCIUM AND CRACK FORMATION AFTER BALLOON DILATATION IN CALCIFIED PLAQUE REQUIRING ROTATIONAL ATHERECTOMY: SERIAL OPTICAL COHERENCE TOMOGRAPHY STUDY

Nobuhiko Maejima, Kiyoshi Hibi, Shotaro Kuji, Kensuke Matsushita, Yugo Minamimoto Minamimoto, Eiichi Akiyama, Yasushi Matsuzawa, Katsutaka Hashiba, Noriaki Iwahashi, Kengo Tsukahara, Masami Kosuge, Toshiaki Ebina, Satoshi Umemura, Kazuo Kimura

JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY 67 ( 13 ) 377 - 377 2016.4

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DOI： 10.1016/S0735-1097(16)30378-3

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Glycemic variability determined by continuous glucose monitoring system predicts left ventricular remodeling in patients with a first ST-segment elevation myocardial infarction

M. Gohbara, N. Iwahashi, S. Kataoka, Y. Hayakawa, K. Sakamaki, E. Akiyama, N. Maejima, K. Tsukahara, K. Hibi, M. Kosuge, T. Ebina, S. Umemura, K. Kimura

Diabetes Technology and Therapeutics 18 S14 - S15 2016.2

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DOI： 10.1089/dia.2016.2502

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Urgent Control of Rapid Atrial Tachyarrhythmia Using Landiolol in Patients With Heart Failure With Severely Reduced Ejection Fraction : An Ultra-Short-Acting beta-blocker for Emergency ADHF

Noriaki Iwahashi, Masaomi Gohbara, Shunsuke Kataoka, Yugo Minamimoto, Eiichi Akiyama, Nobuhiko Maejima, Kengo Tsukahara, Kiyoshi Hibi, Masami Kosuge, Masami Kosuge, Toshiaki Ebina, Satoshi Umemura, Kazuo Kimura

CIRCULATION 132 2015.11

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Low Appendicular Skeletal Muscle Mass is Associated With High Coronary Plaque Complexity in Patients With ST-segment Elevation Myocardial Infarction

Ryosuke Satou, Eiichi Akiyama, Hiroyuki Suzuki, Chika Kawashima, Yasushi Matsuzawa, Masaaki Konishi, Katsutaka Hashiba, Nobuhiko Maejima, Noriaki Iwahashi, Kengo Tsukahara, Kiyoshi Hibi, Masami Kosuge, Toshiaki Ebina, Shinichi Sumita, Satoshi Umemura, Kazuo Kimura

CIRCULATION 132 2015.11

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Predictive Values of ST-segment Elevation in Lead aVR for the Diagnosis of Left Main or 3-Vessel Disease in Patients With Non-ST-segment Elevation Acute Coronary Syndrome

Masami Kosuge, Toshiaki Ebina, Kiyoshi Hibi, Kengo Tsukahara, Noriaki Iwahashi, Nobuhiko Maejima, Eiichi Akiyama, Satoshi Umemura, Kazuo Kimura

CIRCULATION 132 2015.11

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Characteristics of Patients with HFpEF Followed up after a Reperfused First STEMI: The Risk/Benefit of the Administration of Diuretics

Noriaki Iwahashi, Toshiaki Ebina, Satoshi Umemura, Kazuo Kimura

JOURNAL OF CARDIAC FAILURE 21 ( 10 ) S156 - S156 2015.10

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DOI： 10.1016/j.cardfail.2015.08.062

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The Control of Rapid Atrial Tachyarrhythmia in Patients with Heart Failure with Severely Reduced Ejection Fraction: Usefulness of Landiolol

Noriaki Iwahashi, Toshiaki Ebina, Satoshi Umemura, Kazuo Kimura

JOURNAL OF CARDIAC FAILURE 21 ( 10 ) S153 - S153 2015.10

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DOI： 10.1016/j.cardfail.2015.08.045

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Association between blood glucose variability and coronary plaque instability in patients with acute coronary syndromes. International journal

Kozo Okada, Kiyoshi Hibi, Masaomi Gohbara, Shunsuke Kataoka, Keiko Takano, Eiichi Akiyama, Yasushi Matsuzawa, Kenichiro Saka, Nobuhiko Maejima, Mitsuaki Endo, Noriaki Iwahashi, Kengo Tsukahara, Masami Kosuge, Toshiaki Ebina, Peter J Fitzgerald, Yasuhiro Honda, Satoshi Umemura, Kazuo Kimura

Cardiovascular diabetology 14 111 - 111 2015.8

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DOI： 10.1186/s12933-015-0275-3

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Filter thrombosis in patients with venous thromboembolism undergoing a temporary inferior vena cava filter insertion

K. Tsukahara, K. Hashiba, T. Ebina, K. Hibi, N. Iwahashi, N. Maejima, E. Akiyama, K. Kimura, S. Umemura

EUROPEAN HEART JOURNAL 36 1137 - 1137 2015.8

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Hypercapnia in patients with acute heart failure

M. Konishi, E. Akiyama, N. Iwahashi, N. Maejima, K. Tsukahara, K. Hibi, M. Kosuge, T. Ebina, K. Kimura

EUROPEAN HEART JOURNAL 36 155 - 155 2015.8

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Prognostic Value of ST-Segment Elevation in Lead aVR in Patients With Type A Acute Aortic Dissection. International journal

Masami Kosuge, Keiji Uchida, Kiyotaka Imoto, Susumu Isoda, Norihisa Karube, Toshiaki Ebina, Kiyoshi Hibi, Hidefumi Nakahashi, Kengo Tsukahara, Noriaki Iwahashi, Nobuhiko Maejima, Munetaka Masuda, Satoshi Umemura, Kazuo Kimura

Journal of the American College of Cardiology 65 ( 23 ) 2570 - 1 2015.6

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DOI： 10.1016/j.jacc.2015.02.075

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Hypercapnia in patients with acute heart failure

M. Masaaki Konishi, E. Akiyama, H. Suzuki, N. Iwahashi, N. Maejima, K. Tsukahara, K. Hibi, M. Kosuge, T. Ebina, K. Kimura

EUROPEAN JOURNAL OF HEART FAILURE 17 9 - 9 2015.5

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マイクロチップ型フローチャンバーシステムを用いた血栓形成能の評価

ICHIKAWA SHIN'YA, TSUKAHARA KENGO, AKIYAMA EIICHI, MAEJIMA NOBUHIKO, IWAHASHI NORIAKI, HIBI KIYOSHI, KOSUGE MASAMI, EBINA TOSHIAKI, UMEMURA SATOSHI, KIMURA KAZUO

日本血栓止血学会誌 26 ( 2 ) 199 2015.4

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Relation Between the SYNTAX Score and Culprit Vessel Vulnerability in Non-ST-Segment Elevation Acute Coronary Syndrome

Kenichiro Saka, Kiyoshi Hibi, Ken Kozuma, Nobuhiko Maejima, Kozo Okada, Yasushi Matsuzawa, Mitsuaki Endo, Noriaki Iwahashi, Kengo Tsukahara, Masami Kosuge, Toshiaki Ebina, Satoshi Umemura, Kazuo Kimura

JACC-CARDIOVASCULAR IMAGING 8 ( 4 ) 496 - 498 2015.4

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DOI： 10.1016/j.jcmg.2014.07.022

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THE COMBINATION OF DYSSYNCHRONY AND GLOBAL LONGITUDINAL STRAIN BY 3D SPECKLE TRACKING AFTER ST-ELEVATION MYOCARDIAL INFARCTION IS USEFUL FOR PREDICTION OF FINAL INFARCT SIZE AND LEFT VENTRICULAR REMODELING

Noriaki Iwahashi, Masaomi Gohbara, Shunsuke Kataoka, Eiichi Akiyama, Nobuhiko Maejima, Kengo Tsukahara, Kiyoshi Hibi, Masami Kosuge, Toshiaki Ebina, Satoshi Umemura, Kazuo Kimura

JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY 65 ( 10 ) A192 - A192 2015.3

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DOI： 10.1016/S0735-1097(15)60192-9

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ESTIMATION OF ACUTE ONSET GLOBAL LONGITUDINAL STRAIN BY 3D SPECKLE TRACKING AFTER ST-ELEVATION MYOCARDIAL INFARCTION IS USEFUL FOR PREDICTION OF FINAL INFARCT SIZE AND LEFT VENTRICULAR REMODELING

Noriaki Iwahashi, Masaomi Gohbara, Eiichi Akiyama, Shunsuke Kataoka, Nobuhiko Maejima, Kengo Tsukahara, Kiyoshi Hibi, Masami Kosuge, Toshiaki Ebina, Satoshi Umemura, Kazuo Kimura

JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY 65 ( 10 ) A1212 - A1212 2015.3

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DOI： 10.1016/S0735-1097(15)61212-8

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EARLY COMPLETE ATRIOVENTRICULAR BLOCK WITH FAST ATRIAL RATE STRONGLY PREDICTS IN-HOSPITAL ADVERSE CLINICAL OUTCOMES IN PATIENTS WITH REPERFUSED INFERIOR ACUTE MYOCARDIAL INFARCTION

Masami Kosuge, Toshiaki Ebina, Kiyoshi Hibi, Noriaki Iwahashi, Nobuhiko Maejima, Kengo Tsukahara, Eiichi Akiyama, Satoshi Umemura, Kazuo Kimura

JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY 65 ( 10 ) A180 - A180 2015.3

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DOI： 10.1016/S0735-1097(15)60180-2

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GLOBAL LONGITUDINAL STRAIN BY 3D SPECKLE TRACKING AFTER ST-ELEVATION MYOCARDIAL INFARCTION IS USEFUL FOR PREDICTING LEFT VENTRICULAR REMODELING: COMPARISON WITH TC99M-SESTAMIBI

Noriaki Iwahashi, Masaomi Gohbara, Shunsuke Kataoka, Eiichi Akiyama, Nobuhiko Maejima, Kengo Tsukahara, Kiyoshi Hibi, Masami Kosuge, Toshiaki Ebina, Satoshi Umemura, Kazuo Kimura

JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY 65 ( 10 ) A1228 - A1228 2015.3

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DOI： 10.1016/S0735-1097(15)61228-1

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Morphological features of non-culprit plaques on optical coherence tomography and integrated backscatter intravascular ultrasound in patients with acute coronary syndromes

Nobuhiko Maejima, Kiyoshi Hibi, Kenichiro Saka, Naoki Nakayama, Yasushi Matsuzawa, Mitsuaki Endo, Noriaki Iwahashi, Jun Okuda, Kengo Tsukahara, Yoshio Tahara, Masami Kosuge, Toshiaki Ebina, Satoshi Umemura, Kazuo Kimura

EUROPEAN HEART JOURNAL-CARDIOVASCULAR IMAGING 16 ( 2 ) 190 - 197 2015.2

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Aims We sought to compare the morphological features of non-culprit plaques with > 50% diameter stenosis in patients with acute coronary syndromes (ACS) with those of culprit plaques in patients with ACS and stable angina pectoris ( SAP) using optical coherence tomography (OCT) and integrated backscatter intravascular ultrasound (IB-IVUS).
Methods and results A total of 150 culprit and non-culprit coronary plaques (non-culprit vessels) in 150 patients with coronary artery disease were interrogated by OCT before percutaneous coronary intervention (PCI). Patients were categorized as follows: 73 culprit plaques in patients with ACS (ACS-C), 32 non-culprit plaques in patients with ACS (ACS-NC), and 45 culprit plaques in patients with SAP. The fibrous cap thickness was thinner in the ACS-C and ACS-NC groups than in the SAP group and was thinnest in the ACS-C group (ACS-C vs. ACS-NC vs. SAP, 60 vs. 82 vs. 114 mm, P < 0.001). IB-IVUS sub-analysis of 95 patients demonstrated that % lipid volume was greater and % fibrous volume was lower in the ACS-NC group than those in the SAP group (ACS-C vs. ACS-NC vs. SAP, 56.3 +/- 11.0 vs. 59.9 +/- 11.2 vs. 50.1 +/- 13.9%, P < 0.05 and 39.5 +/- 9.0 vs. 35.0 +/- 9.0 vs. 43.9 +/- 11.3%, P < 0.01, respectively).
Conclusion Plaques of non-culprit vessels in patients with ACS had a thinner fibrous cap and a higher percentage of lipid content than culprit plaques in patients with SAP. However, the fibrous cap thickness was thinner in the culprit lesions in patients with ACS than in the non-culprit lesions in patients with ACS, while plaque compositions were not significantly different between the groups.

DOI： 10.1093/ehjci/jeu173

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Morphological features of non-culprit plaques on optical coherence tomography and integrated backscatter intravascular ultrasound in patients with acute coronary syndromes

Nobuhiko Maejima, Kiyoshi Hibi, Kenichiro Saka, Naoki Nakayama, Yasushi Matsuzawa, Mitsuaki Endo, Noriaki Iwahashi, Jun Okuda, Kengo Tsukahara, Yoshio Tahara, Masami Kosuge, Toshiaki Ebina, Satoshi Umemura, Kazuo Kimura

EUROPEAN HEART JOURNAL-CARDIOVASCULAR IMAGING 16 ( 2 ) 190 - 197 2015.2

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Aims We sought to compare the morphological features of non-culprit plaques with > 50% diameter stenosis in patients with acute coronary syndromes (ACS) with those of culprit plaques in patients with ACS and stable angina pectoris ( SAP) using optical coherence tomography (OCT) and integrated backscatter intravascular ultrasound (IB-IVUS).
Methods and results A total of 150 culprit and non-culprit coronary plaques (non-culprit vessels) in 150 patients with coronary artery disease were interrogated by OCT before percutaneous coronary intervention (PCI). Patients were categorized as follows: 73 culprit plaques in patients with ACS (ACS-C), 32 non-culprit plaques in patients with ACS (ACS-NC), and 45 culprit plaques in patients with SAP. The fibrous cap thickness was thinner in the ACS-C and ACS-NC groups than in the SAP group and was thinnest in the ACS-C group (ACS-C vs. ACS-NC vs. SAP, 60 vs. 82 vs. 114 mm, P < 0.001). IB-IVUS sub-analysis of 95 patients demonstrated that % lipid volume was greater and % fibrous volume was lower in the ACS-NC group than those in the SAP group (ACS-C vs. ACS-NC vs. SAP, 56.3 +/- 11.0 vs. 59.9 +/- 11.2 vs. 50.1 +/- 13.9%, P < 0.05 and 39.5 +/- 9.0 vs. 35.0 +/- 9.0 vs. 43.9 +/- 11.3%, P < 0.01, respectively).
Conclusion Plaques of non-culprit vessels in patients with ACS had a thinner fibrous cap and a higher percentage of lipid content than culprit plaques in patients with SAP. However, the fibrous cap thickness was thinner in the culprit lesions in patients with ACS than in the non-culprit lesions in patients with ACS, while plaque compositions were not significantly different between the groups.

DOI： 10.1093/ehjci/jeu173

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Glycemic Variability on Continuous Glucose Monitoring System Predicts Rapid Progression of Non-Culprit Lesions in Patients With Acute Coronary Syndrome.

Shunsuke Kataoka, Masaomi Gohbara, Noriaki Iwahashi, Kentaro Sakamaki, Tatsuya Nakachi, Eiichi Akiyama, Nobuhiko Maejima, Kengo Tsukahara, Kiyoshi Hibi, Masami Kosuge, Toshiaki Ebina, Satoshi Umemura, Kazuo Kimura

Circulation journal : official journal of the Japanese Circulation Society 79 ( 10 ) 2246 - 54 2015

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DOI： 10.1253/circj.CJ-15-0496

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Glycemic Variability Determined by Continuous Glucose Monitoring System Predicts Left Ventricular Remodeling in Patients With a First ST-Segment Elevation Myocardial Infarction.

Masaomi Gohbara, Noriaki Iwahashi, Shunsuke Kataoka, Yoshikazu Hayakawa, Kentaro Sakamaki, Eiichi Akiyama, Nobuhiko Maejima, Kengo Tsukahara, Kiyoshi Hibi, Masami Kosuge, Toshiaki Ebina, Satoshi Umemura, Kazuo Kimura

Circulation journal : official journal of the Japanese Circulation Society 79 ( 5 ) 1092 - 9 2015

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DOI： 10.1253/circj.CJ-14-1226

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Right Ventricular Dysfunction Plays an Important Role in Predicting Non-Response to Tolvaptan Treatment in Patients With Heart Failure With Reduced Ejection Fraction With Chronic Kidney Disease

Noriaki Iwahashi, Masaomi Gohbara, Shunsuke Kataoka, Eiichi Akiyama, Nobuhiko Maejima, Kengo Tsukahara, Kiyoshi Hibi, Masami Kosuge, Toshiaki Ebina, Satoshi Umemura, Kazuo Kimura

CIRCULATION 130 2014.11

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Impact of In-hospital Acute Phase Cardiac Rehabilitation on Long-term Cardiovascular Outcomes in Acute Myocardial Infarction Patients

Chika Kawashima, Yasushi Mtsuzawa, Hiroyuki Suzuki, Eiichi Akiyama, Nobuhiko Maejima, Noriaki Iwahashi, Kengo Tsukahara, Kiyoshi Hibi, Masami Kosuge, Toshiaki Ebina, Satoshi Umemura, Kazuo Kimura

CIRCULATION 130 2014.11

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Estimation of Acute Onset Global Longitudinal Strain by 3D Speckle Tracking After ST -Elevation Myocardial Infarction is Useful for Predicting Left Ventricular Remodeling

Noriaki Iwahashi, Masaomi Gohbara, Eiichi Akiyama, Nobuhiko Maejima, Kengo Tsukahara, Kiyoshi Hibi, Masami Kosuge, Toshiaki Ebina, Satoshi Umemura, Kazuo Kimura

CIRCULATION 130 2014.11

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Glycemic Variability as Determined by a Continuous Glucose Monitoring System Predicts Left Ventricular Dysfunction in Patients With a First ST-Segment Elevation Myocardial Infarction

Masaomi Gohbara, Noriaki Iwahashi, Shunsuke Kataoka, Eiichi Akiyama, Nobuhiko Maejima, Kengo Tsukahara, Kiyoshi Hibi, Masami Kosuge, Toshiaki Ebina, Satoshi Umemura, Kazuo Kimura

CIRCULATION 130 2014.11

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Optimal Gait Speed Cut-off Values According to Age and Gender in Predicting Cardiovascular Events in Patients after Acute Myocardial Infarction

Chika Kawashima, Yasushi Matsuzawa, Hiroyuki Suzuki, Eiichi Akiyama, Nobuhiko Maejima, Noriaki Iwahashi, Kengo Tsukahara, Kiyoshi Hibi, Masami Kosuge, Toshiaki Ebina, Satoshi Umemura, Kazuo Kimura

CIRCULATION 130 2014.11

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ST-Segment Elevation in Leads V5-6 Predicts In-Hospital Adverse Outcomes in Patients With Reperfused Inferior Acute Myocardial Infarction

Masami Kosuge, Toshiaki Ebina, Kiyoshi Hibi, Kengo Tsukahara, Noriaki Iwahashi, Nobuhiko Maejima, Eiichi Akiyama, Satoshi Umemura, Kazuo Kimura

CIRCULATION 130 2014.11

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Diagnostic Efficacy of Instantaneous Wave-free Ratio (iFR), Resting Distal Coronary Artery Pressure / Aortic Pressure, and iFR During Adenosine Administration Among Intermediate Coronary Lesions

Kensuke Matsushita, Kiyoshi Hibi, Eiichi Akiyama, Keiko Takano, Nobuhiko Maejima, Noriaki Iwahashi, Kengo Tsukahara, Masami Kosuge, Toshiaki Ebina, Shinichi Sumida, Satoshi Umemura, Kazuo Kimura

CIRCULATION 130 2014.11

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ST-Segment Elevation in Lead AVR Strongly Predicts Long-Term Adverse Outcomes in Patients With Non-ST-Segment Elevation Acute Coronary Syndrome

Masami Kosuge, Toshiaki Ebina, Kiyoshi Hibi, Kengo Tsukahara, Noriaki Iwahashi, Nobuhiko Maejima, Eiichi Akiyama, Satoshi Umemura, Kazuo Kimura

CIRCULATION 130 2014.11

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Impact of Insulin Resistance on Left Ventricular Remodeling in Patients With a First-Time ST Elevation Acute Myocardial Infarction Without Overt Diabetes Mellitus

Noriaki Iwahashi, Masaomi Gohbara, Shunsuke Kataoka, Eiichi Akiyama, Nobuhiko Maejima, KEngo Tsukahara, Kiyoshi Hibi, Masami Kosuge, Toshiaki Ebina, Satoshi Umemura, Kazuo Kimura

CIRCULATION 130 2014.11

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The Combination of Dyssynchrony and Global Longitudinal Strain by 3D Speckle Tracking After ST-Elevation Myocardial Infarction is Useful for Prediction of Final Infarct Size and Left Ventricular Remodeling

Noriaki Iwahashi, Masaomi Gohbara, Shunsuke Kataoka, Eiichi Akiyama, Nobuhiko Maejima, Kengo Tsukahara, Kiyoshi Hibi, Masami Kosuge, Toshiaki Ebina, Satoshi Umemura, Kazuo Kimura

CIRCULATION 130 2014.11

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Less Body Fat and Skeletal Muscle Mass Correlate with the Severity of Acute Decompensated Heart Failure

Eiichi Akiyama, Masaaki Konishi, Noriaki Iwahashi, Toshiaki Ebina, Kazuo Kimura

JOURNAL OF CARDIAC FAILURE 20 ( 10 ) S161 - S161 2014.10

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DOI： 10.1016/j.cardfail.2014.07.173

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Hypercapnia in Acute Heart Failure Patients with or Without Pulmonary Edema

Masaaki Konishi, Eiichi Akiyama, Noriaki Iwahashi, Toshiaki Ebina, Kazuo Kimura

JOURNAL OF CARDIAC FAILURE 20 ( 10 ) S168 - S168 2014.10

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DOI： 10.1016/j.cardfail.2014.07.209

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Glucagon-like peptide-1 levels on admission for acute myocardial infarction with or without acute hyperglycemia

Masaaki Konishi, Eiichi Akiyama, Yasushi Matsuzawa, Hiroyuki Suzuki, Nobuhiko Maejima, Noriaki Iwahashi, Kengo Tsukahara, Kiyoshi Hibi, Masami Kosuge, Toshiaki Ebina, Satoshi Umemura, Kazuo Kimura

INTERNATIONAL JOURNAL OF CARDIOLOGY 176 ( 3 ) 1214 - 1216 2014.10

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DOI： 10.1016/j.ijcard.2014.07.221

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RV Dysfunction Plays an Important Role in Predicting Non-response to Tolvaptan in Patients with Heart Failure with Reduced Ejection Fraction

Noriaki Iwahashi, Toshiaki Ebina, Kazuo Kimura

JOURNAL OF CARDIAC FAILURE 20 ( 10 ) S174 - S175 2014.10

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DOI： 10.1016/j.cardfail.2014.07.245

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Evaluating the Morphological and Hemodynamic Status in Patients with Ischemic Heart Failure Using Several Imaging Modalities

Noriaki Iwahashi, Toshiaki Ebina, Kazuo Kimura

JOURNAL OF CARDIAC FAILURE 20 ( 10 ) S136 - S136 2014.10

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DOI： 10.1016/j.cardfail.2014.07.021

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急性前壁梗塞再灌流例で若年男性の肥満患者は梗塞サイズが大きく院内予後は不良である

KOSUGE MASAMI, EBINA TOSHIAKI, HIBI KIYOSHI, TSUKAHARA KENGO, IWAHASHI NORIAKI, MAEJIMA NOBUHIKO, AKIYAMA EIICHI, KIMURA KAZUO, UMEMURA SATOSHI

日本内分泌学会雑誌 90 ( 2 ) 759 2014.9

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初回ST上昇型急性心筋梗塞患者における梗塞サイズと心外周囲脂肪Epicardial Adipose Tissueの関係―心臓MRIによる研究―

GOHARA MASAOMI, IWAHASHI NORIAKI, AKIYAMA EIICHI, MAEJIMA NOBUHIKO, TSUKAHARA KENGO, HIBI KIYOSHI, KOSUGE MASAMI, EBINA TOSHIAKI, UMEMURA SATOSHI, KIMURA KAZUO

日本内分泌学会雑誌 90 ( 2 ) 762 2014.9

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Relationship between thin-cap fibroatheroma and plaque progression in patients with coronary artery disease-an intravascular ultrasound and optical coherence tomography study-

K. Takano, K. Hibi, K. Matsushita, N. Maejima, N. Iwahashi, K. Tsukahara, Y. Tahara, M. Kosuge, T. Ebina, K. Kimura

EUROPEAN HEART JOURNAL 35 1145 - 1145 2014.9

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Serial FD-OCT assessment of complex calcified coronary plaque requiring rotational atherectomy

N. Maejima, K. Hibi, M. Konishi, N. Iwahashi, K. Tsukahara, Y. Tahara, M. Kosuge, T. Ebina, S. Umemura, K. Kimura

EUROPEAN HEART JOURNAL 35 1146 - 1146 2014.9

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Clinical usefulness of a QRS scoring system for estimating rapid progression of myocardial infarction in patients with ST-segment elevation myocardial infarction

M. Gohbara, N. Iwahashi, N. Maejima, K. Tsukahara, K. Hibi, M. Kosuge, T. Ebina, S. Umemura, K. Kimura

EUROPEAN HEART JOURNAL 35 460 - 460 2014.9

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Clinical features and prognosis of patients who survived cardiac arrest due to coronary spasm

N. Nakayama, M. Konishi, N. Maejima, N. Iwahashi, K. Tsukahara, K. Hibi, T. Ebina, S. Sumita, K. Kimura, S. Umemura

EUROPEAN HEART JOURNAL 35 937 - 938 2014.9

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Utility of Noninvasive Endothelial Function Test for Prediction of Deep Vein Thrombosis After Total Hip or Knee Arthroplasty

Hiroyuki Suzuki, Yasushi Matsuzawa, Masaaki Konishi, Eiichi Akiyama, Keiko Takano, Naoki Nakayama, Shunsuke Kataoka, Toshiaki Ebina, Masami Kosuge, Kiyoshi Hibi, Kengo Tsukahara, Noriaki Iwahashi, Mitsuaki Endo, Nobuhiko Maejima, Kentaro Shinohara, Naoya Taki, Naoto Mitsugi, Masataka Taguri, Seigo Sugiyama, Hisao Ogawa, Satoshi Umemura, Kazuo Kimura

CIRCULATION JOURNAL 78 ( 7 ) 1723 - + 2014.7

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DOI： 10.1253/circj.CJ-13-1325

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THE EFFECT OF ROTATIONAL ATHERECTOMY ON COMPLEX CALCIFIED CORONARY LESIONS: SERIAL OPTICAL COHERENCE TOMOGRAPHY STUDY

Nobuhiko Maejima, Kiyoshi Hibi, Masaaki Konishi, Noriaki Iwahashi, Kengo Tsukahara, Yoshio Tahara, Masami Kosuge, Toshiaki Ebina, Satoshi Umemura, Kazuo Kimura

JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY 63 ( 12 ) A1779 - A1779 2014.4

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DOI： 10.1016/S0735-1097(14)61782-4

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ASSOCIATION BETWEEN ABDOMINAL FAT DISTRIBUTION AND CORONARY TISSUE CHARACTERISTICS IN PATIENTS WITH ACUTE CORONARY SYNDROMES

Kozo Okada, Kiyoshi Hibi, Yasuhiro Honda, Toshiaki Ebina, Kengo Tsukahara, Masami Kosuge, Yoshio Tahara, Noriaki Iwahashi, Nobuhiko Maejima, Masaaki Konishi, Eiichi Akiyama, Keiko Takano, Naoki Nakayama, Masaomi Gohbara, Zenko Nagashima, Shunsuke Kataoka, Hiroyuki Suzuki, Satoshi Umemura, Kazuo Kimura

JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY 63 ( 12 ) A1796 - A1796 2014.4

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DOI： 10.1016/S0735-1097(14)61799-X

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HIGHER GLUCAGON-LIKE PEPTIDE-1 LEVELS ON ADMISSION WERE ASOCIATED WITH REDUCED INFARCT SIZE AFTER SUCCESSFUL REPERFUSION OF ST ELEVATION ACUTE MYOCARDIAL INFARCTION

Masaaki Konishi, Eiichi Akiyama, Hiroyuki Suzuki, Nobuhiko Maejima, Noriaki Iwahashi, Kengo Tsukahara, Kiyoshi Hibi, Masami Kosuge, Toshiaki Ebina, Satoshi Umemura, Kazuo Kimura

JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY 63 ( 12 ) A249 - A249 2014.4

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DOI： 10.1016/S0735-1097(14)60249-7

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SARCOPENIA IS ASSOCIATED WITH THE SEVERITY OF HEART FAILURE IN PATIENTS WITH ACUTE DECOMPENSATED HEART FAILURE

Eiichi Akiyama, Masaaki Konishi, Yasushi Matsuzawa, Mitsuaki Endo, Hiroyuki Suzuki, Naoki Nakayama, Nobuhiko Maejima, Noriaki Iwahashi, Kengo Tsukahara, Yoshio Tahara, Kiyoshi Hibi, Toshiaki Ebina, Satoshi Umemura, Kazuo Kimura

JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY 63 ( 12 ) A545 - A545 2014.4

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DOI： 10.1016/S0735-1097(14)60545-3

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CLINICAL SIGNIFICANCE OF TWISTING MOTION ESTIMATED BY 3D SPECKLE TRACKING STRAIN ACUTELY AFTER ONSET OF ST-ELEVATION MYOCARDIAL INFARCTION

Noriaki Iwahashi, Masaomi Gohbara, Masaaki Konishi, Kengo Tsukahara, Yoshio Tahara, Kiyoshi Hibi, Masami Kosuge, Toshiaki Ebina, Satoshi Umemura, Kazuo Kimura

JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY 63 ( 12 ) A175 - A175 2014.4

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DOI： 10.1016/S0735-1097(14)60175-3

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Differences in Negative T Waves Between Acute Pulmonary Embolism and Acute Coronary Syndrome

Masami Kosuge, Toshiaki Ebina, Kiyoshi Hibi, Kengo Tsukahara, Noriaki Iwahashi, Satoshi Umemura, Kazuo Kimura

CIRCULATION JOURNAL 78 ( 2 ) 483 - 489 2014.2

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Relation Between Echocardiograms After Return of Spontaneous Circulation and Neurologic Outcomes in Patients Treated With Hypothermia After Out-of-hospital Ventricular Fibrillation Cardiac Arrest: J-PULSE-Hypo Registry

Yoshio Tahara, Kazuo Kimura, Noriaki Iwahashi, Naoto Morimura, Ken Nagao, Naohiro Yonemoto, Hiroyuki Yokoyama, Hiroshi Nonogi

CIRCULATION 128 ( 22 ) 2013.11

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Clinical Significance of Blood Glucose Variability Pattern in the Acute Phase of ST-segment Myocardial Infarction (STEMI)

Kozo Okada, Masaomi Gohbara, Shunsuke Kataoka, Kengo Tsukahara, Toshiaki Ebina, Kiyoshi Hibi, Masami Kosuge, Yoshio Tahara, Nobuhiko Maejima, Noriaki Iwahashi, Masaaki Konishi, Yasushi Matsuzawa, Eiichi Akiyama, Keiko Takano, Naoki Nakayama, Zenko Nagashima, Hiroyuki Suzuki, Shunsuke Matsushita, Satoshi Umemura, Kazuo Kimura

CIRCULATION 128 ( 22 ) 2013.11

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Clinical Usefulness of Twisting Motion Estimated by D-3 Speckle Tracking Strain Acutely After Onset of ST-Elevation Myocardial Infarction

Noriaki Iwahashi, Masaomi Gohbara, Masaaki Konishi, Nobuhiko Majima, Kengo Tsukahara, Yoshio Tahara, Kiyoshi Hibi, Masami Kosuge, Toshiaki Ebina, Toshiyuki Ishikawa, Satoshi Umemura, Kazuo Kimura

CIRCULATION 128 ( 22 ) 2013.11

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Right Ventricular Dysfunction Plays an Important Role in Predicting Non-Response to Tolvaptan Treatment in Patients With Heart Failure With Reduced Ejection Fraction: Strain Echocardiography Study

Noriaki Iwahashi, Masaomi Gohbara, Masaaki Konishi, Nobuhiko Maejima, Kengo Tsukahara, Yoshio Tahara, Kiyoshi Hibi, Masami Kosuge, Toshiaki Ebina, Toshiyuki Ishikawa, Satoshi Umemura, Kazuo Kimura

CIRCULATION 128 ( 22 ) 2013.11

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Differences in Negative T Waves Between Severe Acute Pulmonary Embolism and Acute Coronary Syndrome

Masami Kosuge, Toshiaki Ebina, Kiyoshi Hibi, Kengo Tsukhara, Nobuhiko Maejima, Noriaki Iwahashi, Yoshio Tahara, Masaaki Konishi, Satoshi Umemura, Kazuo Kimura

CIRCULATION 128 ( 22 ) 2013.11

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Global Longitudinal Strain Estimated by 3D Speckle Tracking Acutely After Onset of ST-Elevation Myocardial Infarction is Useful to Predict Final Infarct Size and Left Ventricular Remodeling

Noriaki Iwahashi, Masaomi Gohbara, Masaaki Konishi, Nobuhiko Maejima, Kengo Tsukahara, Yoshio Tahara, Kiyoshi Hibi, Masami Kosuge, Toshiaki Ebina, Toshiyuki Ishikawa, Satoshi Umemura, Kazuo Kimura

CIRCULATION 128 ( 22 ) 2013.11

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Clinical Implication of ST-Segment Elevation in Lead aVR in Patients With Non-ST-Segment Elevation Acute Coronary Syndrome

Masami Kosuge, Toshiaki Ebina, Kiyoshi Hibi, Kengo Tsukahara, Nobuhiko Maejima, Noriaki Iwahashi, Yoshio Tahara, Masaaki Konishi, Satoshi Umemura, Kazuo Kimura

CIRCULATION 128 ( 22 ) 2013.11

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Lower Levels of Low-Density Lipoprotein Cholesterol on Admission Was Associated With Remaining Severe Endothelial Dysfunction After Statin Administration in Patients With ST-Segment Elevation Myocardial Infarction

Hiroyuki Suzuki, Yasushi Matsuzawa, Masaaki Konishi, Eiichi Akiyama, Keiko Takano, Naoki Nakayama, Shunsuke Kataoka, Toshiaki Ebina, Masami Kosuge, Kiyoshi Hibi, Kengo Tsukahara, Noriaki Iwahashi, Nobuaki Maejima, Satoshi Umemura, Kazuo Kimura

CIRCULATION 128 ( 22 ) 2013.11

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Acute Hemoglobin Decrease and Possible Fluid Shift during Heart Failure Hospitalization in Hemodialysis Patients

Masaaki Konishi, Yasushi Matsuzawa, Eiichi Akiyama, Noriaki Iwahashi, Toshiaki Ebina, Satoshi Umemura, Kazuo Kimura

JOURNAL OF CARDIAC FAILURE 19 ( 10 ) S168 - S169 2013.10

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DOI： 10.1016/j.cardfail.2013.08.463

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Association between Glycemic Variability and Coronary Tissue Characteristics in Patients with Acute Coronary Syndromes

Kozo Okada, Kiyoshi Hibi, Yasuhiro Honda, Masaomi Gobara, Shunsuke Kataoka, Toshiaki Ebina, Masami Kosuge, Yoshio Tahara, Kengo Tsukahara, Nobuhiko Maejima, Noriaki Iwahashi, Masaaki Konishi, Yasushi Matsuzawa, Eiichi Akiyama, Naoki Nakayama, Zenko Nagashima, Hiroyuki Suzuki, Satoshi Umemura, Kazuo Kimura

JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY 62 ( 18 ) B195 - B195 2013.10

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DOI： 10.1016/j.jacc.2013.08.1391

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Effect of microchannel and hs-CRP levels on the incidence of in-stent restenosis in patients with acute coronary syndrome

K. Saka, K. Hibi, N. Maejima, N. Iwahashi, M. Endo, K. Tsukahara, Y. Tahara, M. Kosuge, T. Ebina, K. Kimura

EUROPEAN HEART JOURNAL 34 712 - 712 2013.8

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Association between gait speed as a measure of frailty and risk of cardiovascular events after myocardial infarction. International journal

Yasushi Matsuzawa, Masaaki Konishi, Eiichi Akiyama, Hiroyuki Suzuki, Naoki Nakayama, Masayoshi Kiyokuni, Shinichi Sumita, Toshiaki Ebina, Masami Kosuge, Kiyoshi Hibi, Kengo Tsukahara, Noriaki Iwahashi, Mitsuaki Endo, Nobuhiko Maejima, Kenichiro Saka, Katsutaka Hashiba, Kozo Okada, Masataka Taguri, Satoshi Morita, Seigo Sugiyama, Hisao Ogawa, Hironobu Sashika, Satoshi Umemura, Kazuo Kimura

Journal of the American College of Cardiology 61 ( 19 ) 1964 - 72 2013.5

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DOI： 10.1016/j.jacc.2013.02.020

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THE EFFECT OF NIGHTTIME BLOOD PRESSURE VARIABILITY ON LEFT VENTRICULAR HYPERTROPHY AND CAROTID INTIMA MEDIA THICKNESS IN PATIENTS WITH NSTEMI

Shunsuke Kataoka, Kozo Okada, Masaomi Gohbara, Noriaki Iwahashi, Kengo Tsukahara, Yoshio Tahara, Kiyoshi Hibi, Masami Kosuge, Toshiaki Ebina, Satoshi Umemura, Kazuo Kimura

JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY 61 ( 10 ) E1475 - E1475 2013.3

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DOI： 10.1016/S0735-1097(13)61475-8

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MONOCYTOSIS AFTER MYOCARDIAL INFARCTION ACCELERATES ATHEROSCLEROSIS: RESULTS OF A FIVE-YEAR FOLLOW-UP STUDY

Keiko Takano, Kiyoshi Hibi, Masaaki Konishi, Yasushi Matsuzawa, Toshiaki Ebina, Masami Kosuge, Yoshio Tahara, Kengo Tsukahara, Mitsuaki Endo, Noriaki Iwahashi, Nobuhiko Maejima, Kenichirou Saka, Kozo Okada, Eiichi Akiyama, Masaomi Gobara, Zenkou Nagashima, Hiroyuki Suzuki, Kazuo Kimura, Satoshi Umemura

JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY 61 ( 10 ) E198 - E198 2013.3

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DOI： 10.1016/S0735-1097(13)60199-0

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YOUNG OBESE MEN ARE CHARACTERIZED BY MULTIPLE CORONARY RISK FACTORS, A LARGER INFARCT SIZE, AND IMPAIRED MYOCARDIAL REPERFUSION IN PATIENTS WITH ANTERIOR ACUTE MYOCARDIAL INFARCTION

Masami Kosuge, Toshiaki Ebina, Kiyoshi Hibi, Kengo Tsukahara, Noriaki Iwahashi, Nobuhiko Maejima, Yoshio Tahara, Satoshi Umemura, Kazuo Kimura

JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY 61 ( 10 ) E34 - E34 2013.3

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DOI： 10.1016/S0735-1097(13)60035-2

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ASSOCIATION BETWEEN HIGHER GLUCOSE VARIABILITY, DETERMINED BY CONTINUOUS GLUCOSE MONITORING SYSTEM, AND POOR CLINICAL CHARACTERISTICS IN STEMI PATIENTS WITH DYSGLYCEMIA, IN COMPARISON WITH CONVENTIONAL GLYCEMIC PARAMETERS

Kozo Okada, Shunsuke Kataoka, Masami Gohbara, Hiroyuki Suzuki, Zenko Nagashima, Keiko Takano, Eiichi Akiyama, Yasushi Matsuzawa, Masaaki Konishi, Nobuhiko Maejima, Mitsuaki Endo, Noriaki Iwahashi, Kengo Tsukahara, Yoshio Tahara, Kenichiro Saka, Kiyoshi Hibi, Masami Kosuge, Toshiaki Ebina, Satoshi Umemura, Kazuo Kimura

JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY 61 ( 10 ) E93 - E93 2013.3

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DOI： 10.1016/S0735-1097(13)60094-7

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TWISTING MOTION ESTIMATED BY 3D SPECKLE-TRACKING STRAIN ACUTELY ONSET AFTER STEMI PREDICTS INFARCT SIZE AND LV REMODELING

Noriaki Iwahashi, Masaomi Gohbara, Kozo Okada, Nobuhiko Maejima, Mitsuaki Endo, Kengo Tsukahara, Yoshio Tahara, Kiyoshi Hibi, Masami Kosuge, Toshiaki Ebina, Satoshi Umemura, Kazuo Kimura

JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY 61 ( 10 ) E908 - E908 2013.3

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DOI： 10.1016/S0735-1097(13)60908-0

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Differences in negative T waves among acute coronary syndrome, acute pulmonary embolism, and Takotsubo cardiomyopathy. International journal

Masami Kosuge, Toshiaki Ebina, Kiyoshi Hibi, Kengo Tsukahara, Noriaki Iwahashi, Masaomi Gohbara, Yasushi Matsuzawa, Kozo Okada, Satoshi Morita, Satoshi Umemura, Kazuo Kimura

European heart journal. Acute cardiovascular care 1 ( 4 ) 349 - 57 2012.12

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DOI： 10.1177/2048872612466790

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E/e' Two Weeks after Onset Is a Powerful Predictor of Cardiac Death and Heart Failure in Patients with a First-Time ST Elevation Acute Myocardial Infarction

Noriaki Iwahashi, Kazuo Kimura, Masami Kosuge, Kengo Tsukahara, Kiyoshi Hibi, Toshiaki Ebina, Mari Saito, Satoshi Umemura

JOURNAL OF THE AMERICAN SOCIETY OF ECHOCARDIOGRAPHY 25 ( 12 ) 1290 - 1298 2012.12

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DOI： 10.1016/j.echo.2012.09.010

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ST-Segment Elevation in Lead aVR Strongly Predicts 3-Year Adverse Outcomes in Patients With Non-ST-Segment Elevation Acute Coronary Syndrome

Masami Kosuge, Toshiaki Ebina, Kiyoshi Hibi, Kengo Tsukahara, Noriaki Iwahashi, Nobuhiko Maejima, Mitsuaki Endo, Satoshi Morita, Satoshi Umemura, Kazuo Kimura

CIRCULATION 126 ( 21 ) 2012.11

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ST-Segment Depression in Lead aVR Predicts In-Hospital Adverse Outcomes in Patients With Inferior Wall Acute Myocardial Infarction

Masami Kosuge, Toshiaki Ebina, Kiyoshi Hibi, Noriaki Iwahashi, Kengo Tsukahara, Nobuhiko Maejima, Mitsuaki Endo, Satoshi Morita, Satoshi Umemura, Kazuo Kimura

CIRCULATION 126 ( 21 ) 2012.11

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Left Ventricular Dyssynchrony Estimated by 3D Speckle Tracking Echocardiography Acutely Onset after ST-Elevation Myocardial Infarction Predicts Final Infarct Size and Remodeling

Noriaki Iwahashi, Kazuo Kimura, Masaomi Gohbara, Zenko Nagashima, Kozo Okada, Mistuaki Endo, Nobuhiko Maejima, Kengo Tsukahara, Yoshio Tahara, Kiyoshi Hibi, Masami Kosuge, Toshiaki Ebina, Taro Hattori, Mochizuki Hidekazu, Atsuyoshi Miyauchi, Yukiko Ouchi, Eiji Ishikawa, Satoshi Umemura

CIRCULATION 126 ( 21 ) 2012.11

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Left Ventricular Filling Pressure Assessed by E/e ' of Women is Higher than Men in Patients with a First ST Elevation Acute Myocardial Infarction

Noriaki Iwahashi, Kazuo Kimura, Masaomi Gohbara, Mistauaki Endo, Nobihiko Maejima, Kengo Tsukahara, Yoshio Tahara, Kiyoshi Hibi, Masami Kosuge, Toshiaki Ebina, Shinichi Sumita, Toshiyuki Ishikawa, Kazuaki Uchino, Satoshi Umemura

CIRCULATION 126 ( 21 ) 2012.11

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Impact of the Contrast-Induced Nephropathy Definition on Long-term Outcome in Patients With Acute Myocardial Infarction Undergoing Primary Percutaneous Coronary Intervention

Masayoshi Kiyokuni, Masami Kosuge, Toshiaki Ebina, Kiyoshi Hibi, Kengo Tsukahara, Noriaki Iwahashi, Nobuhiko Maejima, Mitsuaki Endo, Yasushi Matsuzawa, Tsutomu Endo, Kazuo Kimura

CIRCULATION 126 ( 21 ) 2012.11

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Paradoxical Hemoconcentration on Admission of Acute Hypertensive Heart Failure Syndrome

Masaaki Konishi, Masaomi Gobara, Eiichi Akiyama, Kozo Okada, Yasushi Matsuzawa, Kenichirou Saka, Noriaki Iwahashi, Nobuhiko Maejima, Mitsuaki Endo, Kengo Tsukahara, Kiyoshi Hibi, Toshiaki Ebina, Kazuo Kimura, Satoshi Umemura

CIRCULATION 126 ( 21 ) 2012.11

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Slow Gait Speed Associated with Advanced Endothelial Dysfunction in Elderly Patients with ST-Segment Elevation Myocardial Infarction

Hiroyuki Suzuki, Yasushi Matsuzawa, Masaaki Konishi, Eiichi Akiyama, Toshiaki Ebina, Kiyoshi Hibi, Masami Kosuge, Kengo Tsukahara, Mitsuaki Endo, Noriaki Iwahashi, Nobuhiko Maejima, Kenichiro Saka, Satoshi Umemura, Kazuo Kimura

CIRCULATION 126 ( 21 ) 2012.11

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Higher Active Glucagon-Like Peptide-1 Level on Admission Was Associated with Reduced Infarct Size in Patients with ST Elevation Acute Myocardial Infarction

Masaaki Konishi, Masaomi Gobara, Eiichi Akiyama, Kozo Okada, Yasushi Matsuzawa, Kenichirou Saka, Nobuhiko Maejima, Noriaki Iwahashi, Mitsuaki Endo, Kengo Tsukahara, Kiyoshi Hibi, Toshiaki Ebina, Kazuo Kimura, Satoshi Umemura

CIRCULATION 126 ( 21 ) 2012.11

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Simple and Accurate Electrocardiographic Criteria for Differentiation Among Acute Coronary Syndrome, Acute Pulmonary Embolism, and Takotsubo Cardiomyopathy

Masami Kosuge, Toshiaki Ebina, Kiyoshi Hibi, Kengo Tsukahara, Noriaki Iwahashi, Nobuhiko Maejima, Mitsuaki Endo, Satoshi Morita, Satoshi Umemura, Kazuo Kimura

CIRCULATION 126 ( 21 ) 2012.11

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Long-term Effects of Ezetimibe Plus Statin Combination vs Double-dose Statin Therapy on Low-density Lipoprotein Cholesterol Lowering in Coronary Artery Disease Patients Pre-treated with Statins; Focus on Proprotein Convertase Subtilisin/Kexin Type 9

Kozo Okada, Noriaki Iwahashi, Tsutomu Endo, Hideo Himeno, Kazuki Fukui, Shunichi Kobayashi, Makoto Shimizu, Yuji Iwasawa, Yukiko Morita, Atsushi Wada, Tomohiko Shigemasa, Yasuyuki Mochida, Tomoaki Shimizu, Reimin Sawada, Kazuaki Uchino, Satoshi Umemura, Kazuo Kimura

CIRCULATION 126 ( 21 ) 2012.11

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Glucose Variability Determined by Continuous Glucose Monitoring System Is More Associated with Poor Clinical Characteristics in ST-Segment Elevation Myocardial Infarction Patients with Type 2 Diabetes Mellitus and Impaired Glucose Tolerance, in Comparison with Hemoglobin A1c Levels

Kozo Okada, Masaomi Gobara, Noriaki Iwahashi, Zenko Nagashima, Hiroyuki Suzuki, Keiko Takano, Eiichi Akiyama, Yasushi Matsuzawa, Masaaki Konishi, Kenichiro Saka, Nobuhiko Maejima, Mitsuaki Endo, Kengo Tsukahara, Yoshio Tahara, Kiyoshi Hibi, Masami Kosuge, Toshiaki Eniba, Kazuo Kimura

CIRCULATION 126 ( 21 ) 2012.11

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Long-term effects of ezetimibe-plus-statin therapy on low-density lipoprotein cholesterol levels as compared with double-dose statin therapy in patients with coronary artery disease

Kozo Okada, Noriaki Iwahashi, Tsutomu Endo, Hideo Himeno, Kazuki Fukui, Shunichi Kobayashi, Makoto Shimizu, Yuji Iwasawa, Yukiko Morita, Atsushi Wada, Tomohiko Shigemasa, Yasuyuki Mochida, Tomoaki Shimizu, Reimin Sawada, Kazuaki Uchino, Satoshi Umemura, Kazuo Kimura

ATHEROSCLEROSIS 224 ( 2 ) 454 - 456 2012.10

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DOI： 10.1016/j.atherosclerosis.2012.07.036

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Relation between peak high sensitivity CRP levels before coronary angiography and culprit lesion morphology in non-ST-segment elevation acute coronary syndrome -An optical coherence tomography study-

Kenichiro Saka, Kiyoshi Hibi, Nobuhiko Maejima, Kozo Okada, Yasushi Matsuzawa, Masaaki Konishi, Noriaki Iwahashi, Mitsuaki Endo, Kengo Tsukahara, Masami Kosuge, Toshiaki Ebina, Satoshi Umemura, Kazuo Kimura

JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY 60 ( 17 ) B75 - B76 2012.10

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Effect of statin pretreatment on the morphology of coronary culprit plaques in patients with stable angina pectoris -An intravascular ultrasound and optical coherence tomography study-

Kenichiro Saka, Kiyoshi Hibi, Nobuhiko Maejima, Kozo Okada, Yasushi Matsuzawa, Masaaki Konishi, Noriaki Iwahashi, Mitsuaki Endo, Kengo Tsukahara, Masami Kosuge, Toshiaki Ebina, Satoshi Umemura, Kazuo Kimura

JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY 60 ( 17 ) B75 - B75 2012.10

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Acute heart failure patients with high initial blood pressure shows paradoxical hemoconcentrateion on admission

M. Konishi, K. Kimura, T. Ebina, K. Hibi, K. Tsukahara, M. Endo, N. Iwahashi, N. Maejima, K. Saka, S. Umemura

EUROPEAN HEART JOURNAL 33 935 - 935 2012.8

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USEFULNESS OF FOUR DIMENSIONAL ECHOCARDIOGRAPHY TO ASSESS LEFT VENTRICULAR MASS: VALIDATION WITH CARDIAC MRI

Masaomi Gohbara, Noriaki Iwahashi, Nobuhiko Maejima, Mitsuaki Endo, Kengo Tsukahara, Kiyoshi Hibi, Masami Kosuge, Toshiaki Ebina, Satoshi Umemura, Kazuo Kimura

JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY 59 ( 13 ) E1108 - E1108 2012.3

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DOI： 10.1016/S0735-1097(12)61109-7

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INFLUENCE OF ACCESS SITE AND ENHANCED RESPONSE TO ANTIPLATELET THERAPY ON ACCESS SITE BLEEDING IN PATIENTS UNDERGOING PERCUTANEOUS CORONARY INTERVENTION

Kengo Tsukahara, Kazuo Kimura, Toshiaki Ebina, Masami Kosuge, Kiyoshi Hibi, Noriaki Iwahashi, Mitsuaki Endo, Nobuhiko Maejima, Satoshi Umemura

JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY 59 ( 13 ) E1407 - E1407 2012.3

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DOI： 10.1016/S0735-1097(12)61408-9

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ST-SEGMENT DEPRESSION IN LEAD AVR STRONGLY PREDICTS ADVERSE OUTCOMES IN PATIENTS WITH ANTEROLATERAL ST-SEGMENT ELEVATION ACUTE MYOCARDIAL INFARCTION

Masami Kosuge, Toshiaki Ebina, Kiyoshi Hibi, Noriaki Iwahashi, Kengo Tsukahara, Nobuhiko Maejima, Mitsuaki Endo, Satoshi Morita, Toshiyuki Ishikawa, Kazuaki Uchino, Satoshi Umemura, Kazuo Kimura

JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY 59 ( 13 ) E415 - E415 2012.3

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DOI： 10.1016/S0735-1097(12)60416-1

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THE MECHANISM OF LONG-TERM LOW-DENSITY LIPOPROTEIN CHOLESTEROL LOWERING EFFECT OF EZETIMIBE-PLUS-STATIN COMBINATION THERAPY IN CORONARY ARTERY DISEASE PATIENTS; COMPARED WITH DOUBLE-DOSE STATIN THERAPY

Kozo Okada, Kazuo Kimura, Noriaki Iwahashi, Tsutomu Endo, Himeno Hideo, Makoto Shimizu, Atsushi Wada, Atsushi Wada, Kazuaki Uchino, Satoshi Umemura

JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY 59 ( 13 ) E1541 - E1541 2012.3

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DOI： 10.1016/S0735-1097(12)61542-3

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ST-SEGMENT DEPRESSION IN LEAD AVR COMBINED WITH NO ST-SEGMENT ELEVATION IN LEAD V1 DIFFERENTIATES TAKOTSUBO CARDIOMYOPATHY FROM ANTERIOR ACUTE MYOCARDIAL INFARCTION

Masami Kosuge, Toshiaki Ebina, Kiyoshi Hibi, Noriaki Iwahashi, Kengo Tsukahara, Nobuhiko Maejima, Mitsuaki Endo, Satoshi Morita, Toshiyuki Ishikawa, Kazuaki Uchino, Satoshi Umemura, Kazuo Kimura

JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY 59 ( 13 ) E423 - E423 2012.3

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DOI： 10.1016/S0735-1097(12)60424-0

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USEFULNESS OF RIGHT VENTRICULAR VOLUME ANALYSIS WITH FOUR DIMENSIONAL ECHOCARDIOGRAPHY TO MEASURE RIGHT VENTRICULAR VOLUME AND FUNCTION: VALIDATION WITH CARDIAC MRI

Masaomi Gohbara, Noriaki Iwahashi, Nobuhiko Maejima, Mitsuaki Endo, Kengo Tsukahara, Kiyoshi Hibi, Masami Kosuge, Toshiaki Ebina, Satoshi Umemura, Kazuo Kimura

JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY 59 ( 13 ) E1147 - E1147 2012.3

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DOI： 10.1016/S0735-1097(12)61148-6

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RELATION BETWEEN THE SYNTAX SCORE AND CULPRIT LESION MORPHOLOGY IN NON-ST-SEGMENT ELEVATION ACUTE CORONARY SYNDROME -AN OPTICAL COHERENCE TOMOGRAPHY STUDY

Kenichiro Saka, Kiyoshi Hibi, Nobuhiko Maejima, Mitsuaki Endo, Noriaki Iwahashi, Kengo Tsukahara, Masami Kosuge, Toshiaki Ebina, Satoshi Umemura, Kazuo Kimura

JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY 59 ( 13 ) E136 - E136 2012.3

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DOI： 10.1016/S0735-1097(12)60137-5

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ASSESSMENT OF CORONARY DISSECTION AFTER PERCUTANOUS CORONARY INTERVENTION BY OPTICAL COHERENCE TOMOGRAPHY -COMPARISON WITH INTRAVASCULAR ULTRASOUND-

Nobuhiko Maejima, Kiyoshi Hibi, Kenichiro Saka, Mitsuaki Endo, Noriaki Iwahashi, Kengo Tsukahara, Masami Kosuge, Toshiaki Ebina, Satoshi Umemura, Kazuo Kimura

JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY 59 ( 13 ) E144 - E144 2012.3

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DOI： 10.1016/S0735-1097(12)60145-4

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LEFT VENTRICULAR DYSSYNCHRONY ESTIMATED BY REAL TIME 3D ECHOCARDIOGRAPHY ACUTELY ONSET AFTER ST-ELEVATION MYOCARDIAL INFARCTION PREDICTS FINAL INFARCT SIZE AND LEFT VENTRICULAR REMODELING

Noriaki Iwahashi, Masami Kosuge, Mitsuaki Endo, Nobuhiko Maejima, Kengo Tsukahara, Kiyoshi Hibi, Toshiaki Ebina, Satoshi Umemura, Kazuo Kimura

JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY 59 ( 13 ) E1114 - E1114 2012.3

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DOI： 10.1016/S0735-1097(12)61115-2

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Percutaneous cardiopulmonary support in pulmonary embolism with cardiac arrest

Katsutaka Hashiba, Jun Okuda, Nobuhiko Maejima, Noriaki Iwahashi, Kengo Tsukahara, Yoshio Tahara, Kiyoshi Hibi, Masami Kosuge, Toshiaki Ebina, Tsutomu Endo, Satoshi Umemura, Kazuo Kimura

RESUSCITATION 83 ( 2 ) 183 - 187 2012.2

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DOI： 10.1016/j.resuscitation.2011.10.019

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Implications of ST-Segment Elevation in Leads V-5 and V-6 in Patients With Reperfused Inferior Wall Acute Myocardial Infarction

Masami Kosuge, Toshiaki Ebina, Kiyoshi Hibi, Noriaki Iwahashi, Satoshi Morita, Mitsuaki Endo, Nobuhiki Maejima, Masaomi Gouhara, Zenkou Nagashima, Satoshi Umemura, Kazuo Kimura

AMERICAN JOURNAL OF CARDIOLOGY 109 ( 3 ) 314 - 319 2012.2

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DOI： 10.1016/j.amjcard.2011.09.013

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Differences in Negative T Waves Between Takotsubo Cardiomyopathy and Reperfused Anterior Acute Myocardial Infarction

Masami Kosuge, Toshiaki Ebina, Kiyoshi Hibi, Noriaki Iwahashi, Kengo Tsukahara, Mitsuaki Endo, Nobuhiko Maejima, Zenko Nagashima, Hiroyuki Suzuki, Satoshi Morita, Satoshi Umemura, Kazuo Kimura

CIRCULATION JOURNAL 76 ( 2 ) 462 - 468 2012.2

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DOI： 10.1253/circj.CJ-11-1036

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PCI in patients with vulnerable plaque using Finter device

日比潔, 遠藤光明, 上妻謙, 坂賢一, 前島信彦, 塚原健吾, 松澤泰志, 岩橋徳明, 田原良雄, 高野桂子, 岡田興三, 海老名俊明, 一色高明, 梅村敏, 木村一雄

日本冠疾患学会雑誌 18 ( 4 ) 2012

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Effects of aortic valve replacement on left ventricular dyssynchrony in aortic stenosis with narrow QRS complex. International journal

Haruhiko Abe, Satoshi Nakatani, Hideaki Kanzaki, Noriaki Iwahashi, Takuya Hasegawa, Masafumi Kitakaze, Kunio Miyatake

Journal of the American Society of Echocardiography : official publication of the American Society of Echocardiography 24 ( 12 ) 1358 - 64 2011.12

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DOI： 10.1016/j.echo.2011.09.005

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Left Ventricular Dyssynchrony Estimated by Real time 3D Echocardiography Acutely Onset after ST-Elevation Myocardial Infarction Predicts Left Ventricular Remodeling

Noriaki Iwahashi, Masami Kosuge, Nobuhiko Maejima, Mitsuaki Endo, Kengo Tsukahara, Yoshio Tahara, Kiyoshi Hibi, Toshiaki Ebina, Shinichi Sumita, Kazuaki Uchino, Toshiyuki Ishikawa, Satoshi Umemura, Kazuo Kimura

CIRCULATION 124 ( 21 ) 2011.11

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Duration of Temporary Inferior Vena Cava Filter for Acute Pulmonary Embolism

Katsutaka Hashiba, Yasushi Matsuzawa, Toshiaki Ebina, Masami Kosuge, Kiyoshi Hibi, Yoshio Tahara, Kengo Tsukahara, Noriaki Iwahashi, Mitsuaki Endo, Nobuhiko Maejima, Kenichiro Saka, Masaaki Konishi, Kozo Okada, Eiichi Akiyama, Masaomi Goubara, Zenkou Nagashima, Hiroyuki Suzuki, Kazuo Kimura

CIRCULATION 124 ( 21 ) 2011.11

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The Prevalence and Comorbidity of Nonspecific Troponin Elevation Detected by Highly Sensitive Assay in Patients with Acute Chest Pain

Masaaki Konishi, Hiroyuki Suzuki, Kozo Okada, Yasushi Matsuzawa, Katsutaka Hashiba, Kenichirou Saka, Nobuhiko Maejima, Noriaki Iwahashi, Mitsuaki Endo, Kengo Tsukahara, Kiyoshi Hibi, Toshiaki Ebina, Kazuo Kimura, Satoshi Umemura

CIRCULATION 124 ( 21 ) 2011.11

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Comparison of Prognostic Values of Contemporary Contrast-Induced Nephropathy Definitions in Patients with Acute Myocardial Infarction Undergoing Emergency Coronary Angiography

Masayoshi Kiyokuni, Masami Kosuge, Tsutomu Endo, Toshiaki Ebina, Kiyoshi Hibi, Kengo Tsukahara, Noriaki Iwahashi, Mitsuaki Endo, Nobuhiko Maejima, Satoshi Umemura, Kazuo Kimura

CIRCULATION 124 ( 21 ) 2011.11

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Clinical Implications of ST-Segment Elevation in Leads V5-6 in Patients with Reperfused Inferior Wall Acute Myocardial Infarction

Masami Kosuge, Toshiaki Ebina, Kiyoshi Hibi, Mitsuaki Endo, Nobuhiko Maejima, Noriaki Iwahashi, Satoshi Morita, Kazuaki Uchino, Toshiyuki Ishikawa, Satoshi Umemura, Kazuo Kimura

CIRCULATION 124 ( 21 ) 2011.11

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Differences in Electrocardiographic Findings Between Takotsubo Cardiomyopathy and Reperfused Non-Q-Wave Anterior Acute Myocardial Infarction

Masami Kosuge, Toshiaki Ebina, Kiyoshi Hibi, Kengo Tsukahara, Noriaki Iwahashi, Mitsuaki Endo, Nobuhiko Maejima, Satoshi Morita, Kazuaki Uchino, Toshiyuki Ishikawa, Satoshi Umemura, Kazuo Kimura

CIRCULATION 124 ( 21 ) 2011.11

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Long-Term Effect of Ezetimibe-Plus-Statin vs Double-Dose Statin on Low-Density Lipoprotein Cholesterol Lowering in Coronary Artery Disease Patients Pre-Treated with a Statin; Focus on Cholesterol Absorption and Synthesis

Kozo Okada, Kazuo Kimura, Noriaki Iwahashi, Tsutomu Endo, Hideo Himeno, Kazuki Fukui, Shunichi Kobayashi, Makoto Shimizu, Yuji Iwasawa, Yukiko Morita, Atsushi Wada, Tomohiko Shigemasa, Yasuyuki Mochida, Tomoaki Shimizu, Reimin Sawada, Kazuaki Uchino, Satoshi Umemura

CIRCULATION 124 ( 21 ) 2011.11

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Gait Speed and Cardiovascular Events After Myocardial Infarction

Yasushi Matsuzawa, Masaaki Konishi, Masayoshi Kiyokuni, Eiichi Akiyama, Hiroyuki Suzuki, Toshiaki Ebina, Masami Kosuge, Kiyoshi Hibi, Yoshio Tahara, Kengo Tsukahara, Noriaki Iwahashi, Mitsuaki Endo, Nobuhiko Maejima, Kenichiro Saka, Katsutaka Hashiba, Kozo Okada, Zenko Nagashima, Masataka Taguri, Masaomi Gohbara, Satoshi Umemura, Kazuo Kimura

CIRCULATION 124 ( 21 ) 2011.11

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ST-Segment Elevation in Lead aVR Strongly Predicts Adverse Outcomes at 1 Year in Patients with Non-ST-Segment Elevation Acute Coronary Syndrome

Masami Kosuge, Toshiaki Ebina, Kiyoshi Hibi, Noriaki Iwahashi, Nobuhiko Maejima, Mitsuaki Endo, Kengo Tsukahara, Satoshi Morita, Kazuaki Uchino, Toshiyuki Ishikawa, Satoshi Umemura, Kazuo Kimura

CIRCULATION 124 ( 21 ) 2011.11

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Elevated Heart Rate Two Weeks after Onset, Despite Successful Reperfusion Therapy, Indicates Poor Prognosis in Patients with a First ST-Elevation Acute Myocardial Infarction

Noriaki Iwahashi, Masami Kosuge, Mitsuaki Endo, Nobuhiko Maejima, Kengo Tsukahara, Yoshio Tahara, Kiyoshi Hibi, Toshiaki Ebina, Shinichi Sumita, Toshiyuki Ishikawa, Kazuaki Uchino, Satoshi Umemura, Kazuo Kimura

CIRCULATION 124 ( 21 ) 2011.11

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Relation between the multivessel disease and culprit lesion morphology in acute coronary syndrome -An optical coherence tomography study-

Kenichiro Saka, Kiyoshi Hibi, Nobuhiko Maejima, Tomokazu Sakano, Yasushi Matsuzawa, Noriaki Iwahashi, Mitsuaki Endo, Kengo Tsukahara, Masaaki Ebina, Satoshi Umemura, Kazuo Kimura

JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY 58 ( 20 ) B176 - B176 2011.11

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Clinical Usefulness of Additional Treatment With Ezetimibe in Patients With Coronary Artery Disease on Statin Therapy - From the Viewpoint of Cholesterol Metabolism

Kozo Okada, Kazuo Kimura, Noriaki Iwahashi, Tsutomu Endo, Hideo Himeno, Kazuki Fukui, Shunichi Kobayashi, Makoto Shimizu, Yuji Iwasawa, Yukiko Morita, Atsushi Wada, Tomohiko Shigemasa, Yasuyuki Mochida, Tomoaki Shimizu, Reimin Sawada, Kazuaki Uchino, Satoshi Umemura

CIRCULATION JOURNAL 75 ( 10 ) 2496 - 2504 2011.10

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DOI： 10.1253/circj.CJ-11-0391

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Usefulness of Plasma B-Type Natriuretic Peptide in the Assessment of Disease Severity and Prediction of Outcome after Aortic Valve Replacement in Patients with Severe Aortic Stenosis

Noriaki Iwahashi, Satoshi Nakatani, Satoshi Umemura, Kazuo Kimura, Masafumi Kitakaze

JOURNAL OF THE AMERICAN SOCIETY OF ECHOCARDIOGRAPHY 24 ( 9 ) 984 - 991 2011.9

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DOI： 10.1016/j.echo.2011.03.012

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心筋梗塞の冠インターベンション (特集心筋梗塞診療の最新情報) -- (治療の実際)

岩橋徳明, 木村一雄

臨牀と研究 88 ( 9 ) 1117 - 1123 2011.9

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Other Link： http://search.jamas.or.jp/link/ui/2011352694
Up-to-Date Information Ischemic Cardiac Disease 急性心筋梗塞に対する再灌流療法

岩橋徳明, 木村一雄

サーキュレーション・アップ・トゥ・デート 6 ( 4 ) 396 - 405 2011.8

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Impact of concomitant use of proton-pump inhibitors and thienopyridine derivatives on the antiplatelet effects

Kengo Tsukahara, Kazuo Kimura, Satoshi Morita, Toshiaki Ebina, Masami Kosuge, Kiyoshi Hibi, Noriaki Iwahashi, Mitsuaki Endo, Nobuhiko Maejima, Teruyasu Sugano, Satoshi Umemura

JOURNAL OF CARDIOLOGY 57 ( 3 ) 275 - 282 2011.5

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DOI： 10.1016/j.jjcc.2011.01.003

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THE RELATIONSHIP BETWEEN HIGH ON-TREATMENT PLATELET REACTIVITY AND RAPID ANGIOGRAPHIC PROGRESSION OF NON-CULPRIT CORONARY LESIONS IN PATIENTS WITH ACUTE CORONARY SYNDROMES

Kengo Tsukahara, Kazuo Kimura, Toshiaki Ebina, Masami Kosuge, Kiyoshi Hibi, Noriaki Iwahashi, Mitsuaki Endo, Nobuhiko Maejima, Satoshi Umemura

JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY 57 ( 14 ) E928 - E928 2011.4

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DOI： 10.1016/S0735-1097(11)60928-5

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EFFECT OF HIGH SENSITIVITY CRP LEVELS AND IMPAIRED RENAL FUNCTION ON THE TISSUE CHARACTERISTICS AND MORPHOLOGY OF CORONARY CULPRIT PLAQUES IN PATIENTS WITH STABLE ANGINA PECTORIS AND MILD-TO- MODERATE CHRONIC KIDNEY DISEASE: AN INTEGRATED BACKSCATTER INTRAVASCULAR ULTRASOUND AND OPTICAL COHERENCE TOMOGRAPHY STUDY

Kenichiro Saka, Kiyoshi Hibi, Nobuhiko Maejima, Naoki Nakayama, Hiroyuki Suzuki, Zenko Nagashima, Masayoshi Kiyokuni, Kouzou Okada, Yasushi Matsuzawa, Masaaki Konishi, Katsutaka Hashiba, Noriaki Iwahashi, Mitsuaki Endo, Kenigo Tsukahara, Yoshio Tahara, Masami Kosuge, Toshiaki Ebina, Satoshi Umemura, Kazuo Kimura

JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY 57 ( 14 ) E1739 - E1739 2011.4

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DOI： 10.1016/S0735-1097(11)61739-7

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POSTPRANDIAL GLUCAGON-LIKE PEPTIDE-1 LEVELS REFLECT IMPAIRED GLUCOSE TOLERANCE AND EXTENT OF CORONARY ATHEROSCLEROSIS IN NON-DIABETIC PATIENTS WITH CORONARY ARTERY DISEASE

Fumiyuki Otsuka, Masaaki Konishi, Masami Kosuge, Yasushi Matsuzawa, Zenkou Nagashima, Nobuhiko Maejima, Mitsuaki Endo, Noriaki Iwahashi, Kengo Tsukahara, Kiyoshi Hibi, Toshiaki Ebina, Satoshi Umemura, Kazuo Kimura

JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY 57 ( 14 ) E629 - E629 2011.4

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DOI： 10.1016/S0735-1097(11)60629-3

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LONG-TERM EFFECT OF EZETIMIBE-STATIN COMBINATION THERAPY ON LOW-DENSITY LIPOPROTEIN CHOLESTEROL LOWERING IN PATIENTS WITH CORONARY ARTERY DISEASE; FOCUS ON CHOLESTEROL ABSORPTION AND SYNTHESIS

Kozo Okada, Kazuki Fukui, Hideo Himeno, Tutomu Endo, Makoto Shimizu, Shunichi Kobayashi, Tomohiko Shigemasa, Yukiko Morita, Atsushi Wada, Tomoaki Shimizu, Yasuyuki Mochida, Reimin Sawada, Tomoaki Ishigami, Kazuaki Uchino, Noriaki Iwahashi, Kazuo Kimura, Satoshi Umemura

JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY 57 ( 14 ) E524 - E524 2011.4

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DOI： 10.1016/S0735-1097(11)60524-X

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GREATER ST-SEGMENT ELEVATION IN LEAD AVR IS ASSOCIATED WITH WORSE OUTCOMES IN PATIENTS WITH NON-ST-SEGMENT ELEVATION ACUTE CORONARY SYNDROME

Masami Kosuge, Toshiaki Ebina, Kiyoshi Hibi, Satoshi Morita, Mitsuaki Endo, Nobuhiko Maejima, Noriaki Iwahashi, Kengo Tsukahara, Toshiyuki Ishikawa, Kazuaki Iwahashi, Satoshi Umemura, Kazuo Kimura

JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY 57 ( 14 ) E974 - E974 2011.4

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DOI： 10.1016/S0735-1097(11)60974-1

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Relation Between Hyperinsulinemia and Nonculprit Plaque Characteristics in Nondiabetic Patients With Acute Coronary Syndromes

Takayuki Mitsuhashi, Kiyoshi Hibi, Masami Kosuge, Satoshi Morita, Naohiro Komura, Ikuyoshi Kusama, Fumiyuki Otsuka, Mitsuaki Endo, Noriaki Iwahashi, Jun Okuda, Kengo Tsukahara, Toshiaki Ebina, Satoshi Umemura, Kazuo Kimura

JACC-CARDIOVASCULAR IMAGING 4 ( 4 ) 392 - 401 2011.4

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DOI： 10.1016/j.jcmg.2011.02.004

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LEFT ATRIAL VOLUME INDEX (LAVI) OVER LATE DIASTOLIC MITRAL ANNULAR VELOCITY (A') IS A POWERFUL PREDICTOR OF CARDIAC DEATH AND CONGESTIVE HEART FAILURE (CHF) IN PATIENTS WITH A FIRST ST-ELEVATION ACUTE MYOCARDIAL INFARCTION (STEMI)

Noriaki Iwahashi, Masami Kosuge, Mitsuaki Endo, Nobuhiko Maejima, Kengo Tsukahara, Yoshio Tahara, Kiyoshi Hibi, Toshiaki Ebina, Shinichi Sumita, Satoshi Umemura, Kazuo Kimura

JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY 57 ( 14 ) E702 - E702 2011.4

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DOI： 10.1016/S0735-1097(11)60702-X

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An Early and Simple Predictor of Severe Left Main and/or Three-Vessel Disease in Patients With Non-ST-Segment Elevation Acute Coronary Syndrome

Masami Kosuge, Toshiaki Ebina, Kiyoshi Hibi, Satoshi Morita, Mitsuaki Endo, Nobuhiki Maejima, Noriaki Iwahashi, Kozo Okada, Toshiyuki Ishikawa, Satoshi Umemura, Kazuo Kimura

AMERICAN JOURNAL OF CARDIOLOGY 107 ( 4 ) 495 - 500 2011.2

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DOI： 10.1016/j.amjcard.2010.10.005

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High QRS score on admission strongly predicts impaired myocardial reperfusion in patients with a first anterior acute myocardial infarction.

Masami Kosuge, Toshiaki Ebina, Kiyoshi Hibi, Noriaki Iwahashi, Kengo Tsukahara, Mitsuaki Endo, Nobuhiko Maejima, Katsutaka Hashiba, Hiroyuki Suzuki, Satoshi Umemura, Kazuo Kimura

Circulation journal : official journal of the Japanese Circulation Society 75 ( 3 ) 626 - 32 2011

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DOI： 10.1253/circj.CJ-10-1053

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Impact of statin pretreatment on the incidence of plaque rupture in ST-elevation acute myocardial infarction

Fumiyuki Otsuka, Kiyoshi Hibi, Ikuyoshi Kusama, Mitsuaki Endo, Masami Kosuge, Noriaki Iwahashi, Jun Okuda, Kengo Tsukahara, Toshiaki Ebina, Sunao Kojima, Seigo Sugiyama, Hisao Ogawa, Satoshi Umemura, Kazuo Kimura

ATHEROSCLEROSIS 213 ( 2 ) 505 - 511 2010.12

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DOI： 10.1016/j.atherosclerosis.2010.09.005

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The Development of Negative T Waves After Initial ST-Segment Elevation Differs Between Takotsubo Cardiomyopathy and Reperfused Anterior Acute Myocardial Infarction

Masami Kosuge, Toshiaki Ebina, Kiyoshi Hibi, Satoshi Morita, Noriaki Iwahashi, Mitsuaki Endo, Nobuhiko Maejima, Kengo Tsukahara, Kazuaki Uchino, Toshiyuki Ishikawa, Satoshi Umemura, Kazuo Kimura

CIRCULATION 122 ( 21 ) 2010.11

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High QRS Score on Admission Strongly Predicts Impaired Myocardial Reperfusion in Patients With a First Anterior Acute Myocardial Infarction

Masami Kosuge, Toshiaki Ebina, Kiyoshi Hibi, Satoshi Morita, Noriaki Iwahashi, Mitsuaki Endo, Nobuhiko Maejima, Kengo Tsukahara, Satoshi Umemura, Kazuo Kimura

CIRCULATION 122 ( 21 ) 2010.11

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The Definition Utilized Influences the Rates and Predictors of Contrast-Induced Nephropathy After Emergency Coronary Angiography For Acute Myocardial Infarction

Masayoshi Kiyokuni, Masami Kosuge, Toshiaki Ebina, Kiyoshi Hibi, Kengo Tsukahara, Noriaki Iwahashi, Mitsuaki Endo, Nobuhiko Maejima, Satoshi Umemura, Kazuo Kimura

CIRCULATION 122 ( 21 ) 2010.11

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Measuring the Baseline Cholesterol Absorption and Synthesis Marker Can Predict the LDL-C Lowering Response to Ezetimibe-Statin Combination Therapy in Patients with Coronary Artery Disease: A Multi-Center Prospective Randomized Trial

Kozo Okada, Taku Fukuoka, Toshihiko Saitoh, Tutomu Endo, Kazuaki Uchino, Kazuaki Fukui, Shunichi Kobayashi, Makoto Shimizu, Yuji Iwasawa, Yukiko Morita, Atsushi Wada, Tomohiko Shigemasa, Yasuyuki Mochida, Noriaki Iwahashi, Satoshi Umemura, Kazuo Kimura

CIRCULATION 122 ( 21 ) 2010.11

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High-Response to Antiplatelet Therapy and the Increasing Risk of Bleeding

Kengo Tsukahara, Kazuo Kimura, Toshiaki Ebina, Masami Kosuge, Kiyoshi Hibi, Noriaki Iwahashi, Nobuhiko Maejima, Mitsuaki Endo, Satoshi Umemura

CIRCULATION 122 ( 21 ) 2010.11

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ST-Segment Elevation in Lead aVR is the Strongest Predictor of Severe Left Main or 3-Vessel Disease in Patients with Non-ST-Segment Elevation Acute Coronary Syndrome

Masami Kosuge, Toshiaki Ebina, Kiyoshi Hibi, Satoshi Morita, Noriaki Iwahashi, Nobuhiki Maejima, Mitsuaki Endo, Kengo Tsukahara, Kazuaki Uchino, Toshiyuki Ishikawa, Satoshi Umemura, Kazuo Kimura

CIRCULATION 122 ( 21 ) 2010.11

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Left Atrial Volume Index (LAVI) over Late Diastolic Mitral Annular Velocity (a') is a Powerful Predictor of Cardiac Death and Heart Failure in Patients with a First ST Elevation Acute Myocardial Infarction

Noriaki Iwahashi, Masami Kosuge, Mitsuaki Endo, Nobuhiko Maejima, Kengo Tsukahara, Yoshio Tahara, Kiyoshi Hibi, Toshiaki Ebina, Shinichi Sumita, Satoshi Umemura, Kazuo Kimura

CIRCULATION 122 ( 21 ) 2010.11

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P2-035 薬剤溶出ステントを留置された患者への服薬指導と院外薬局への情報提供の必要性 : ステント血栓症発症事例からの検討(一般演題ポスター発表,薬剤管理指導・情報提供,臨床から学び臨床へと還元する医療薬学)

橋本容子, 川上佳那子, 岩橋徳明, 宮崎三恵子, 海老名俊明, 木村一雄, 橋本真也

日本医療薬学会年会講演要旨集 20 396 - 396 2010.10

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Simple and Accurate Electrocardiographic Criteria to Differentiate Takotsubo Cardiomyopathy From Anterior Acute Myocardial Infarction

Masami Kosuge, Toshiaki Ebina, Kiyoshi Hibi, Satoshi Morita, Jun Okuda, Noriaki Iwahashi, Kengo Tsukahara, Tatsuya Nakachi, Masayoshi Kiyokuni, Toshiyuki Ishikawa, Satoshi Umemura, Kazuo Kimura

JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY 55 ( 22 ) 2514 - 2516 2010.6

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DOI： 10.1016/j.jacc.2009.12.059

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Impact of Ultrasound Attenuation and Plaque Rupture as Detected by Intravascular Ultrasound on the Incidence of No-Reflow Phenomenon After Percutaneous Coronary Intervention in ST-Segment Elevation Myocardial Infarction

Mitsuaki Endo, Kiyoshi Hibi, Tomoaki Shimizu, Naohiro Komura, Ikuyoshi Kusama, Fumiyuki Otsuka, Takayuki Mitsuhashi, Noriaki Iwahashi, Jun Okuda, Kengo Tsukahara, Masami Kosuge, Toshiaki Ebina, Satoshi Umemura, Kazuo Kimura

JACC-CARDIOVASCULAR INTERVENTIONS 3 ( 5 ) 540 - 549 2010.5

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DOI： 10.1016/j.jcin.2010.01.015

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Impact of High-Responsiveness to Dual Antiplatelet Therapy on Bleeding Complications in Patients Receiving Drug-Eluting Stents

Kengo Tsukahara, Kazuo Kimura, Satoshi Morita, Toshiaki Ebina, Masami Kosuge, Kiyoshi Hibi, Jun Okuda, Noriaki Iwahashi, Nobuhiko Maejima, Tatsuya Nakachi, Fumiyuki Ohtsuka, Katsutaka Hashiba, Yoshio Tahara, Teruyasu Sugano, Satoshi Umemura

CIRCULATION JOURNAL 74 ( 4 ) 679 - 685 2010.4

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DOI： 10.1253/circj.CJ-09-0601

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Plaque Location in the Left Anterior Descending Coronary Artery and Tissue Characteristics in Angina Pectoris: An Integrated Backscatter Intravascular Ultrasound Study

Naohiro Komura, Kiyoshi Hibi, Ikuyoshi Kusama, Fumiyuki Otsuka, Takayuki Mitsuhashi, Mitsuaki Endo, Noriaki Iwahashi, Jun Okuda, Kengo Tsukahara, Masami Kosuge, Toshiaki Ebina, Satoshi Umemura, Kazuo Kimura

CIRCULATION JOURNAL 74 ( 1 ) 142 - 147 2010.1

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DOI： 10.1253/circj.CJ-09-0389

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Association Between Admission Neutrophil to Lymphocyte Ratio and Angiographical Findings in Patients With Non-ST-Segment Elevation Acute Coronary Syndromes

Tatsuya Nakachi, Masami Kosuge, Kiyoshi Hibi, Toshiaki Ebina, Kengo Tsukahara, Jun Okuda, Noriaki Iwahashi, Yoshio Tahara, Satoshi Umemura, Kazuo Kimura

CIRCULATION 120 ( 18 ) S1009 - S1009 2009.11

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Prognostic Implications of Left Ventricular Mass and Geometry Following a First ST-Elevation Acute Myocardial Infarction

Noriaki Iwahashi, Masami Kosuge, Jun Okuda, Kengo Tsukahara, Yoshio Tahara, Kiyoshi Hibi, Toshiaki Ebina, Shinichi Sumita, Toshiaki Ishikawa, Kazuaki Uchino, Satoshi Umemura, Satoshi Umemura, Kazuo Kimura

CIRCULATION 120 ( 18 ) S356 - S356 2009.11

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Prolonged QRS Duration is a Strong Predictor of Adverse Outcomes in Patients With Non-ST-Segment Elevation Acute Coronary Syndrome

Masami Kosuge, Kazuo Kimura, Satoshi Morita, Toshiyuki Ishikawa, Toshiaki Ebina, Kiyoshi Hibi, Jyun Okuda, Noriaki Iwahashi, Kengo Tsukahara, Kazuaki Uchino, Satoshi Umemura

CIRCULATION 120 ( 18 ) S1007 - S1007 2009.11

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Positive T Wave in Lead aVR and No Negative T Wave in Lead V1 Distinguishes Tako-tsubo Cardiomyopathy From Recanalized Anterior Acute Myocardial Infarction

Masami Kosuge, Kazuo Kimura, Satoshi Morita, Toshiaki Ebina, Kiyoshi Hibi, Jyun Okuda, Noriaki Iwahashi, Kengo Tsukahara, Kazuaki Uchino, Toshiyuki Ishikawa, Satoshi Umemura

CIRCULATION 120 ( 18 ) S775 - S775 2009.11

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A Simple Electrocardiographic Criterion for Differentiating Tako-tsubo Cardiomyopathy From Anterior Acute Myocardial Infarction

Masami Kosuge, Toshiaki Ebina, Kiyoshi Hibi, Satoshi Morita, Noriaki Iwahashi, Jyun Okuda, Kengo Tsukahara, Kazuaki Uchino, Toshiyuki Ishikawa, Satoshi Umemura, Kazuo Kimura

CIRCULATION 120 ( 18 ) S1007 - S1007 2009.11

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ST-Segment Depression in Lead aVR: A Useful Predictor of Impaired Myocardial Reperfusion in Patients With Anterolateral ST-Segment Elevation Acute Myocardial Infarction

Masami Kosuge, Toshiaki Ebina, Kiyoshi Hibi, Satoshi Morita, Toshiyuki Ishikawa, Kazuaki Uchino, Kengo Tsukahara, Noriaki Iwahashi, Jyun Okuda, Satoshi Umemura, Kazuo Kimura

CIRCULATION 120 ( 18 ) S1007 - S1008 2009.11

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Impact of the ApoB/A1-Ratio on the Prediction of the Elevation of Left Ventricular Filling Pressure After a First STEMI

Noriaki Iwahashi, Masami Kosuge, Jun Okuda, Kengo Tsukahara, Yoshio Tahara, Kiyoshi Hibi, Toshiaki Ebina, Shinichi Sumita, Toshiaki Ishikawa, Kazuaki Uchino, Satoshi Umemura, Kazuo Kimura

CIRCULATION 120 ( 18 ) S489 - S489 2009.11

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A Case of Acute Occlusion of the Left Circumflex Artery after Stenting for the Proximal Left Anterior Descending Artery, Successful Bail Out by Kissing Stent : Case Report

OKUDA Jun, HIBI Kiyoshi, EBINA Toshiaki, KOSUGE Masami, TSUKAHARA Kengo, IWAHASHI Noriaki, UMEMURA Satoshi, KIMURA Kazuo

Cardiovascular intervention and therapeutics 1 ( 1 ) 65 - 70 2009.9

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Impact of Drug-eluting Stents on the Peristent Tissue Compositions: A Serial Volumetric Analysis Using Quantitative Integrated Backscatter Intravascular Ultrasound

Kiyoshi Hibi, Mitsuaki Endo, Nobuhiko Maejima, Naoki Nakayama, Naohiro Komura, Fumiyuki Otsuka, Noriaki Iwahashi, Jun Okuda, Kengo Tsukahara, Masami Kosuge, Toshiaki Ebina, Satoshi Umemura, Kazuo Kimura

AMERICAN JOURNAL OF CARDIOLOGY 104 ( 6A ) 17D - 18D 2009.9

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PJ-521 Association between Admission Neutrophil to Lymphocyte Ratio and Angiographical Findings in Patients with Non-ST-Segment Elevation Acute Coronary Syndrome(PJ088,ACS/AMI (Clinical/Pathophysiology) 2 (IHD),Poster Session (Japanese),The 73rd Annual Scientific Meeting of The Japanese Circulation Society)

Nakachi Tatsuya, Kosuge Masami, Hibi Kiyoshi, Ebina Toshiaki, Tukahara Kengo, Okuda Jun, Iwahashi Noriaki, Tahara Yoshio, Umemura Satoshi, Kimura Kazuo

Circulation journal : official journal of the Japanese Circulation Society 73 678 - 678 2009.3

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PJ-257 Clinical Characteristics and Prognosis of Patients with Acute Myocardial Infarction due to Left Main Coronary Artery Disease(PJ043,ACS/AMI (Clinical/Treatment) 2 (IHD),Poster Session (Japanese),The 73rd Annual Scientific Meeting of The Japanese Circulation Society)

Okuda Jun, Kosuge Masami, Ebina Toshiaki, Sumita shinichi, Hibi Kiyoshi, Tahara Yoshio, Tukahara Kengo, Iwahashi Noriaki, maejima nobuhiko, Nakachi Tatsuya, mitsuhashi takayuki, Ohtsuka Fumiyuki, hashiba Katsutaka, Komura Naohiro, Minami Kazutoshi, Kiyokuni Masayoshi, Nakayama Naoki, Umemura Satoshi, Kimura Kazuo

Circulation journal : official journal of the Japanese Circulation Society 73 610 - 610 2009.3

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PJ-264 Impact of Drug-Eluting Stents on the Peristent Plaque Compositions : A Serial Volumetric Analysis Using Quantitative Integrated Backscatter Intravascular Ultrasound(PJ045,Coronary Revascularization, PCI (DES) 1 (IHD),Poster Session (Japanese),The 73rd Annual Scientific Meeting of The Japanese Circulation Society)

Endo Mitsuaki, Hibi Kiyoshi, Komura Naohiro, Ohtsuka Fumiyuki, Mitsuhashi Takayuki, Iwahashi Noriaki, Nozawa Naoki, Okuda Jun, Tukahara Kengo, Kosuge Masami, Ebina Toshiaki, Endo Tsutomu, Umemura Satoshi, Kimura Kazuo

Circulation journal : official journal of the Japanese Circulation Society 73 612 - 612 2009.3

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PJ-386 E/e' is the Strongest Predictor of Major Adverse Cardio-Cerebrovascular Events in Patients with a First Anterior ST-Elevation Acute Myocardial Infarction(PJ065,ACS/AMI (Clinical/Treatment) 3 (IHD),Poster Session (Japanese),The 73rd Annual Scientific Meeting of The Japanese Circulation Society)

Iwahashi Noriaki, Kosuge Masami, Kiyokuni Masayoshi, Nakayama Naoki, Komura Naohiro, Minami Kazutoshi, Hashiba Katsutaka, Ohtsuka Fumiyuki, Nakachi Tatsuya, Mitsuhashi Takayuki, Maejima Nobuhiko, Okuda Jun, Tukahara Kengo, Tahara Yoshio, Hibi Kiyoshi, Ebina Toshiaki, Ishikawa Toshiyuki, Umemura Satoshi, Kimura Kazuo

Circulation journal : official journal of the Japanese Circulation Society 73 643 - 643 2009.3

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PJ-112 Impact of Carotid Artery IMT on the Subclinical Regional Myocardial Dysfunction and MACCE within 1Year : Tissue Strain Imaging Study(PJ019,Atherosclerosis (Clinical/Treatment) 1 (IHD),Poster Session (Japanese),The 73rd Annual Scientific Meeting of The Japanese Circulation Society)

Hirabayashi Michiko, Iwahashi Noriaki, Harada Yukie, Yonezawa Hiromi, Sumita Shinichi, Kimura Kazuo, Miyajima Eiji

Circulation journal : official journal of the Japanese Circulation Society 73 574 - 574 2009.3

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PJ-656 Non-high-density Lipoprotein Cholesterol Levels are Associated with Multiple Complex Coronary Lesions in Patients with Acute Myocardial Infarction(PJ110,ACS/AMI (Clinical/Pathophysiology) 1 (IHD),Poster Session (Japanese),The 73rd Annual Scientific Meeting of The Japanese Circulation Society)

Ohtsuka Fumiyuki, Hibi Kiyoshi, Kosuge Masami, Mitsuhashi Takayuki, Nakachi Tatsuya, Komura Naohiro, Iwahashi Noriaki, Okuda Jun, Tukahara Kengo, Tahara Yoshio, Ebina Toshiaki, Umemura Satoshi, Kimura Kazuo

Circulation journal : official journal of the Japanese Circulation Society 73 711 - 711 2009.3

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OE-005 Impact of Long-term Statin Pretreatment on the Incidence of Plaque Rupture and Infarct Size in ST-elevation Acute Myocardial Infarction(OE01,Cardiovascular Pharmacology (Clinical) (H),Oral Presentation (English),The 73rd Annual Scientific Meeting of The Japanese Circulation Society)

Ohtsuka Fumiyuki, Hibi Kiyoshi, Kosuge Masami, Mitsuhashi Takayuki, Nakachi Tatsuya, Komura Naohiro, Iwahashi Noriaki, Okuda Jun, Tukahara Kengo, Tahara Yoshio, Ebina Toshiaki, Umemura Satoshi, Kimura Kazuo

Circulation journal : official journal of the Japanese Circulation Society 73 175 - 175 2009.3

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OJ-131 Statin Pretreatment Prevents Contrast-Induced Nephopathy in Patients with Acute Myocardial Infarction(OJ22,ACS/AMI (Clinical/Pathophysiology) (IHD),Oral Presentation (Japanese),The 73rd Annual Scientific Meeting of The Japanese Circulation Society)

Kiyokuni Masayoshi, Kosuge Masami, Ebina Toshiaki, Hibi Kiyoshi, Tahara Yoshio, Tukahara Kengo, Okuda Jun, Iwahashi Noriaki, Maejima Nobuhiko, Nakachi Tatsuya, Mitsuhashi Takayuki, Ohtsuka Fumiyuki, Hashiba Katsutaka, Komura Naohiro, Minami Kazutoshi, Nakayama Naoki, Umemura Satoshi, Kimura Kazuo

Circulation journal : official journal of the Japanese Circulation Society 73 318 - 318 2009.3

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PE-569 Different Influence of Insulin Resistance and Low Density Lipoprotein Cholesterol on the Tissue Components of Culprit and Non-Culprit Plaques(PE095,Atherosclerosis (Clinical/Pathophysiology) (IHD),Poster Session (English),The 73rd Annual Scientific Meeting of the Japanese Circulation Society)

Mitsuhashi Takayuki, Hibi Kiyoshi, Nakayama Naoki, Komura Naohiro, Ohtsuka Fumiyuki, Maejima Nobuhiko, Kiyokuni Masayoshi, Minami Kazutoshi, Hashiba Katsutaka, Nakachi Tatsuya, Iwahashi Noriaki, Okuda Jun, Tukahara Kengo, Tahara Yoshio, Kosuge Masami, Ebina Toshiaki, Umemura Satoshi, Kimura Kazuo

Circulation journal : official journal of the Japanese Circulation Society 73 543 - 543 2009.3

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PJ-230 Medial Annular E/e' has a Strongest Relationship with Plasma BNP among Echocardiographical Parameters after a First ST-Elevation AMI(PJ039,Cardiac Function (Clinical) 2 (M),Poster Session (Japanese),The 73rd Annual Scientific Meeting of The Japanese Circulation Society)

Iwahashi Noriaki, Kosuge Masami, Kiyokuni Masayoshi, Nakayama Naoki, Komura Naohiro, Minami Kazutoshi, Hashiba Katsutaka, Ohtsuka Fumiyuki, Nakachi Tatsuya, Mitsuhashi Takayuki, Maejima Nobuhiko, Okuda Jun, Tukahara Kengo, Tahara Yoshio, Hibi Kiyoshi, Ebina Toshiaki, Ishikawa Toshiyuki, Umemura Satoshi, Kimura Kazuo

Circulation journal : official journal of the Japanese Circulation Society 73 603 - 604 2009.3

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PJ-766 Acute Hyperglycemia Attenuates the Beneficial Effects of Preinfarction Angina in Patients with Acute Myocardial Infarction Treated with Fibrinolysis(PJ129,Myocardial Ischemia-reperfusion (Basic, Clinical) (IHD),Poster Session (Japanese),The 73rd Annual Scientific Meeting of The Japanese Circulation Society)

Kiyokuni Masayoshi, Kosuge Masami, Ebina Toshiaki, Hibi Kiyoshi, Tahara Yoshio, Tukahara Kengo, Okuda Jun, Iwahashi Noriaki, Maejima Nobuhiko, Nakachi Tatsuya, Mitsuhashi Takayuki, Ohtsuka Fumiyuki, Hashiba Katsutaka, Komura Naohiro, Minami Kazutoshi, Nakayama Naoki, Umemura Satoshi, Kimura Kazuo

Circulation journal : official journal of the Japanese Circulation Society 73 739 - 739 2009.3

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PJ-815 Can Integrated Backscatter Intravascular Ultrasound Predict the Thickness of Coronary Calcification as Assessed by Optical Coherence Tomography(PJ137,Intravascular Imagings 1 (I),Poster Session (Japanese),The 73rd Annual Scientific Meeting of The Japanese Circulation Society)

Maejima Nobuhiko, Hibi Kiyoshi, Nakayama Naoki, Kiyokuni Masayoshi, Minami Kazutoshi, Komura Naohiro, Hashiba Katsutaka, Ohtsuka Fumiyuki, Mitsuhashi Takayuki, Nakachi Tatsuya, Iwahashi Noriaki, Okuda Jun, Tukahara Kengo, Tahara Yoshio, Kosuge Masami, Ebina Toshiaki, Sumita Shinichi, Umemura Satoshi, Kimura Kazuo

Circulation journal : official journal of the Japanese Circulation Society 73 751 - 752 2009.3

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PJ-485 Ratio of Late Transmitral Velocity to Averaged Mitral Annular Late Diastolic Velocity is Powerful Index after a First ST-Elevation AMI(PJ082,Echo/Doppler (Myocardium) (I),Poster Session (Japanese),The 73rd Annual Scientific Meeting of The Japanese Circulation Society)

Iwahashi Noriaki, Kosuge Masami, Kiyokuni Masayoshi, Nakayama Naoki, Komura Naohiro, Minami Kazutoshi, Hashiba Katsutaka, Ohtsuka Fumiyuki, Nakachi Tatsuya, Mitsuhashi Takayuki, Maejima Nobuhiko, Okuda Jun, Tukahara Kengo, Tahara Yoshio, Hibi Kiyoshi, Ebina Toshiaki, Ishikawa Toshiyuki, Umemura Satoshi, Kimura Kazuo

Circulation journal : official journal of the Japanese Circulation Society 73 668 - 668 2009.3

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Intensive and Moderate Lipid Lowering Therapy to Prevent Progression of Coronary Atherosclerosis in Patients With Acute Coronary Syndrome in Japan: A Serial Intravascular Ultrasound Study

Naohiro Komura, Kiyoshi Hibi, Fumiyuki Otsuka, Takayuki Mitsuhashi, Noriaki Iwahashi, Jun Okuda, Kenngo Tsukahara, Masami Kosuge, Toshiaki Ebina, Satoshi Umemura, Kazuo Kimura

JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY 53 ( 10 ) A204 - A204 2009.3

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Impact of Drug-Eluting Stents on the Peristent Plaque Compositions: A Serial Volumetric Analysis Using Quantitative Integrated Backscatter Intravascular Ultrasound

Mitsuaki Endo, Kiyoshi Hibi, Naohiro Komura, Fumiyuki Otsuka, Takayuki Mitsuhashi, Noriaki Iwahashi, Naoki Nozawa, Jun Okuda, Kengo Tsukahara, Masami Kosuge, Toshiaki Ebina, Tsutomu Endo, Satoshi Umemura, Kazuo Kimura

JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY 53 ( 10 ) A13 - A13 2009.3

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Different Influence of Insulin Resistance and Low-Density Lipoprotein Cholesterol on the Tissue Components of Culprit and Nonculprit Plaques in Patients With Unstable Angina

Takayuki Mitsuhashi, Kiyoshi Hibi, Naoki Nakayama, Naohiro Komura, Fumiyuki Otsuka, Nobuhiko Maejima, Masayoshi Kiyokuni, Kazutoshi Minami, Katsutaka Hashiba, Tatsuya Nakachi, Noriaki Iwahashi, Jun Okuda, Kengo Tsukahara, Yoshio Tahara, Masami Kosuge, Toshiaki Ebina, Shinichi Sumita, Satoshi Umemura, Kazuo Kimura

JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY 53 ( 10 ) A423 - A423 2009.3

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Renal Dysfunction and Rapid Coronary Artery Disease Progression in Patients With Non-ST-Segment Elevation Acute Coronary Syndrome

Tatsuya Nakachi, Masami Kosuge, Kiyoshi Hibi, Toshiaki Ebina, Kengo Tsukahara, Jun Okuda, Noriaki Iwahashi, Yoshio Tahara, Satoshi Umemura, Kazuo Kimura

JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY 53 ( 10 ) A353 - A354 2009.3

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Tissue Doppler Imaging Including E/e ' Is a Powerful Predictor of Major Adverse Cardio Cerebrovascular Events in Patients With a First Anterior ST-Elevation Acute Myocardial Infarction

Noriaki Iwahashi, Masami Kosuge, Jun Okuda, Kengo Tsukahara, Yoshio Tahara, Kiyoshi Hibi, Toshiaki Ebina, Shinichi Sumita, Toshiyuki Ishikawa, Kazuaki Uchino, Satoshi Umemura, Kazuo Kimura

JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY 53 ( 10 ) A234 - A234 2009.3

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Effects of Pretreatment With Statins on Infarct Size in Patients With Acute Myocardial Infarction Who Receive Fibrinolytic Therapy

Masayoshi Kiyokuni, Masami Kosuge, Toshiaki Ebina, Kiyoshi Hibi, Kengo Tsukahara, Jun Okuda, Noriaki Iwahashi, Nobuhiko Maejima, Ikuyoshi Kusama, Naohiro Komura, Naoki Nakayama, Satoshi Umemura, Kazuo Kimura

CIRCULATION JOURNAL 73 ( 2 ) 330 - 335 2009.2

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Early, simple, noninvasive predictors of left main or 3-vessel disease in patients with non-ST-segment elevation acute coronary syndromes

KOSUGE M, Ebina Toshiaki, Hibi Kiyoshi, Okuda Jun, Iwahashi Noriaki, Tukahara Kengo, Mitsuhashi Takayuki, Hashiba Katsutaka, Ohtsuka Fumiyuki, Komura Naohiro, Nakayama Naoki, Tahara Yoshio, Minami Kazutoshi, Kiyokuni Masayoshi, Maejima Nobuhiko, Nakachi Tatsuya, Umemura Satoshi, Kimura Kazuo

Circ J 608 - 608 2009

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20) 重症多枝冠攣縮の不安定狭心症の診断に12誘導心電図連続モニタリングが有用であった1例(第207回日本循環器学会関東甲信越地方会)

南一敏, 小菅雅美, 海老名俊明, 日比潔, 塚原健吾, 奥田純, 岩橋徳明, 木村一雄, 梅村敏

Circulation journal : official journal of the Japanese Circulation Society 72 1011 - 1011 2008.10

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Impact of Long-Term Statin Pretreatment on the Incidence of Plaque Rupture and Infarct Size in ST-Elevation Acute Myocardial Infarction

Fumiyuki Otsuka, Kiyoshi Hibi, Ikuyoshi Kusama, Mitsuaki Endo, Masami Kosuge, Takayuki Mitsuhashi, Naohiro Komura, Noriaki Iwahashi, Jun Okuda, Kengo Tsukahara, Yoshio Tahara, Toshiaki Ebina, Satoshi Umemura, Kazuo Kimura

CIRCULATION 118 ( 18 ) S584 - S584 2008.10

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Posterior Involvement Attenuates Predictive Value of ST-Segment Elevation in Lead V4R for Right Ventricular Involvement in Inferior Acute Myocardial Infarction

Masami Kosuge, Kazuo Kimura, Toshiaki Ebina, Kiyoshi Hibi, Kengo Tsukahara, Jyun Okuda, Noriaki Iwahashi, Toshiyuki Ishikawa, Kazuaki Uchino, Satoshi Umemura

CIRCULATION 118 ( 18 ) S578 - S579 2008.10

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Impaired Glucose Tolerance is Associated With Positive Coronary Artery Remodeling in Non-diabetic Patients with ST-elevation Acute Myocardial Infarction

Fumiyuki Otsuka, Kiyoshi Hibi, Ikuyoshi Kusama, Mitsuaki Endo, Masami Kosuge, Takayuki Mitsuhashi, Naohiro Komura, Noriaki Iwahashi, Jun Okuda, Kengo Tsukahara, Yoshio Tahara, Toshiaki Ebina, Satoshi Umemura, Kazuo Kimura

CIRCULATION 118 ( 18 ) S1113 - S1113 2008.10

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Early, Simple, Noninvasive Predictors of Left Main or 3-Vessel Disease in Patients with Non-ST-Segment Elevation Acute Coronary Syndrome

Masaml Kesuge, Kazuo Kimura, Toshiyuki Ishikawa, Kazuald Uchino, Toshiaki Ebina, Kiyoshi Hibi, Noriaki Iwahashi, Kengo Tsukahara, Jyun Okuda, Satoshi Umemura

CIRCULATION 118 ( 18 ) S579 - S580 2008.10

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Effects of Long-term Pretreatment with Statins on Infarct Size in Patients with Acute Myocardial Infarction who Receive Fibrinolytic Therapy

Masayoshi Kiyokuni, Masami Kosuge, Shinichi Sumita, Toshiaki Ebina, Kiyoshi Hibi, Yoshio Tahara, Kengo Tsukahara, Jun Okuda, Noriaki Iwahashi, Satoshi Umemura, Kazuo Kimura

JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY 45 S16 - S16 2008.10

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DOI： 10.1016/j.yjmcc.2008.09.643

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Hyper-Responder to Dual Antiplatelet Therapy and Bleeding Complications

Kengo Tsukahara, Kazuo Kimura, Toshiaki Ebina, Masami Kosuge, Kiyoshi Hibi, Jun Okuda, Noriaki Iwahashi, Satoshi Umemura

CIRCULATION 118 ( 18 ) S477 - S477 2008.10

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91) 長時間作用型カルシウム拮抗薬の大量服用により二峰性の急性循環不全をきたした1例(第206回日本循環器学会関東甲信越地方会)

西田憲史, 田原良雄, 豊田洋, 小菅宇之, 鈴木範行, 中山尚貴, 羽柴克孝, 岩橋徳明, 奥田純, 塚原健吾, 日比潔, 小菅雅美, 海老名俊明, 木村一雄

Circulation journal : official journal of the Japanese Circulation Society 72 948 - 948 2008.4

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FRS-044 Deep Ultrasound Attenuation Detected by Intravascular Ultrasound Impacts Quantitative Coronary Flow during Percutaneous Coronary Intervention in Acute Myocardial Infarction(New Clinical Approach for Acute Myocardial Infarction(IHD),Featured Research Session,The 72nd Annual Scientific Meeting of the Japanese Circulation Society)

Endo Mitsuaki, Hibi Kiyoshi, Shimizu Tomoaki, Kiyokuni Masayoshi, Nakayama Naoki, Minami Kazutoshi, Komura Naohiro, Hashiba Katsutaka, Kusama Ikuyoshi, Ohtsuka Fumiyuki, Nakachi Tatsuya, Mitsuhashi Takayuki, Iwahashi Noriaki, Kosuge Jun, Tsukahara Kengo, Tahara Yoshio, Kosuge Masami, Ebina Toshiaki, Sumita Shinichi, Umemura Satoshi, Kimura Kazuo

Circulation journal : official journal of the Japanese Circulation Society 72 153 - 153 2008.3

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PJ-766 Predictive Value of the Change in White Blood Cell Count for Left Ventricular Function Following Anterior Acute Myocardial Infarction(Acute myocardial infarction, clinical(pathophysiology)(03)(IHD),Poster Session(Japanese),The 72nd Annual Scientific Meeting of the Japanese Circulation Society)

Kosuge Masami, Kimura Kazuo, Ebina Toshiaki, Hibi Kiyoshi, Okuda Jun, Iwahashi Noriaki, Tukahara Kengo, Endoh Mitsuaki, Mituhasi Takayuki, Nakachi Tatsuya, Hashiba Katsutaka, Ohtsuka Fumiyuki, Kiyokuni Masayoshi, Nakayama Naoki, Minami Kazutoshi, Umemura Satoshi

Circulation journal : official journal of the Japanese Circulation Society 72 704 - 704 2008.3

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PJ-765 Relation of High-Density Lipoprotein Cholesterol and Cigarette Smoking to the Incidence of Plaque Rupture in ST-elevation Myocardial Infarction(Acute myocardial infarction, clinical(pathophysiology)(03)(IHD),Poster Session(Japanese),The 72nd Annual Scientific Meeting of the Japanese Circulation Society)

Otsuka Fumiyuki, Hibi Kiyoshi, Kusama Ikuyoshi, Endoh Mitsuaki, Mitsuhashi Takayuki, Komura Naohiro, Kosuge Masami, Iwahashi Noriaki, Okuda Jun, Tukahara Kengo, Tahara Yoshio, Ebina Toshiaki, Umemura Satoshi, Kimura Kazuo

Circulation journal : official journal of the Japanese Circulation Society 72 704 - 704 2008.3

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OJ-259 Impact of Hyperinsulinemia on Tissue Characteristics of Non-culprit Plaque in Non-diabetic Patients with Acute Coronary Syndrome(Diabetes / Obesity / Metabolic syndrome(03)(H),Oral Presentation (Japanese),The 72nd Annual Scientific Meeting of the Japanese Circulation Society)

Mitsuhashi Takayuki, Hibi Kiyoshi, Kosuge Masami, Sumita Shinichi, Ebina Toshiaki, Tahara Yoshio, Tukahara Kengo, Okuda Jun, Iwahashi Noriaki, Endoh Mitsuaki, Nakachi Tatsuya, Ohtsuka Fumiyuki, Kusama Ikuyoshi, Komura Naohiro, Minami Kazutoshi, Umemura Satoshi, Kimura Kazuo

Circulation journal : official journal of the Japanese Circulation Society 72 354 - 354 2008.3

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PJ-575 C-Reactive Protein Elevation and Rapid Angiographic Progression of Nonculprit Lesion in Patients With Non-ST-segment Elevation Acute Coronary Syndrome(Acute coronary syndrome, basic/clinical(05)(IHD),Poster Session(Japanese),The 72nd Annual Scientific Meeting of the Japanese Circulation Society)

Nakachi Tatsuya, Kosuge Masami, Ebina Toshiaki, Hibi Kiyoshi, Tukahara Kengo, Okuda Jun, Iwahashi Noriaki, Tahara Yoshio, Sugano Teruyasu, Umemura Satoshi, Kimura Kazuo

Circulation journal : official journal of the Japanese Circulation Society 72 657 - 657 2008.3

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PJ-583 Does Statin Pre-treatment Promote Thrombolysis in Patients with Acute Myocardial Infarction Treated with Thrombolytic Therapy?(Acute myocardial infarction, clinical(diagnosis/treatment)(11)(IHD),Poster Session(Japanese),The 72nd Annual Scientific Meeting of the Japanese Circulation Society)

Kiyokuni Masayoshi, Kosuge Masami, Okuda Jun, Ebina Toshiaki, Hibi Kiyoshi, Tahara Yoshio, Tukahara Kengo, Iwahashi Noriaki, Endoh Mitsuaki, Mitsuhashi Takayuki, Nakati Tatsuya, Ohtsuka Fumiyuki, Kusama Ikuyoshi, Hashiba Katsutaka, Komura Naohiro, Minami Kazutoshi, Nakayama Naoki, Kimura Kazuo, Umemura Satoshi

Circulation journal : official journal of the Japanese Circulation Society 72 659 - 659 2008.3

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PJ-420 Impact of Chronic Statin Pre-treatment on the Incidence of Plaque Rupture Detected by Intravascular Ultrasound in ST-elevation Acute Myocardial Infarction(Cardiovascular pharmacology, basic/clinical(05)(H),Poster Session(Japanese),The 72nd Annual Scientific Meeting of the Japanese Circulation Society)

Otsuka Fumiyuki, Hibi Kiyoshi, Kusama Ikuyoshi, Endoh Mitsuaki, Mitsuhashi Takayuki, Komura Naohiro, Kosuge Masami, Iwahashi Noriaki, Okuda Jun, Tukahara Kengo, Tahara Yoshio, Ebina Toshiaki, Umemura Satoshi, Kimura Kazuo

Circulation journal : official journal of the Japanese Circulation Society 72 617 - 618 2008.3

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FRS-098 Strain-rate by Tissue Strain Imaging is Powerful Tool to Evaluate Ischemic Diastolic Stunning Course after Reperfused ST-Elevation Acute Coronary Syndrome(Leading Edge in Echocardiographic Technologies(2)(I),Featured Research Session,The 72nd Annual Scientific Meeting of the Japanese Circulation Society)

Iwahashi Noriaki, Kimura Kazuo, Nakayama Naoki, Kiyokuni Masayoshi, Minami Kazutoshi, Komura Naohiro, Hashiba Katsutaka, Kusama Ikuyoshi, Ohtsuka Fumiyuki, Mitsuhashi Takayuki, Nakachi Tatsuya, Endoh Mitsuaki, Okuda Jun, Tukahara Kengo, Tahara Yoshio, Hibi Kiyoshi, Kosuge Masami, Sugano Teruyasu, Ebina Toshiaki, Ishikawa Toshiyuki, Umemura Satoshi

Circulation journal : official journal of the Japanese Circulation Society 72 170 - 170 2008.3

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PJ-088 Impact of Early Reperfusion Therapy on The Regional Left Ventricular Relaxation of ST-elevation Acute Coronary Syndrome : Tissue Strain Imaging Study(Echo/Doppler(12)(I),Poster Session(Japanese),The 72nd Annual Scientific Meeting of the Japanese Circulation Society)

Iwahashi Noriaki, Kimura Kazuo, Nakayama Naoki, Kiyokuni Masayoshi, Minami Kazutoshi, Komura Naohiro, Hashiba Katsutaka, Kusama Ikuyoshi, Ohtsuka Fumiyuki, Mitsuhashi Takayuki, Nakachi Tatsuya, Endoh Mitsuaki, Okuda Jun, Tukahara Kengo, Tahara Yoshio, Hibi Kiyoshi, Kosuge Masami, Ebina Toshiaki, Ishikawa Toshiyuki, Umemura Satoshi

Circulation journal : official journal of the Japanese Circulation Society 72 532 - 532 2008.3

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PE-269 Does Tissue Characteristics Differ Between Proximal and Distal Segment of Left Anterior Descending Coronary Artery? : Integrated Backscatter Intravascular Ultrasound Study(Atherosclerosis, clinical(06)(IHD),Poster Session(English),The 72nd Annual Scientific Meeting of the Japanese Circulation Society)

Komura Naohiro, Hibi Kiyoshi, Minami Kazutoshi, Kusama Ikuyoshi, Ohtsuka Fumiyuki, Mitsuhashi Takayuki, Endoh Mitsuaki, Iwahashi Noriaki, Okuda Jun, Tukahara Kengo, Kosuge Masami, Ebina Toshiaki, Umemura Satoshi, Kimura Kazuo

Circulation journal : official journal of the Japanese Circulation Society 72 427 - 427 2008.3

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PJ-685 Transmural Myocardial Strain Profile is an Useful Method to Estimate the Regional Myocardial Damage after Reperfused ST-Elevation Acute Myocardial Infarction(Echo / Doppler(17)(I),Poster Session(Japanese),The 72nd Annual Scientific Meeting of the Japanese Circulation Society)

Iwahashi Noriaki, Kimura Kazuo, Kiyokuni Masayoshi, Minami Kazutoshi, Komura Naohiro, Kusama Ikuyoshi, Hashiba Katsutaka, Ohtsuka Fumiyuki, Mitsuhashi Takayuki, Nakachi Tatsuya, Endoh Mitsuaki, Okuda Jun, Tukahara Kengo, Tahara Yoshio, Hibi Kiyoshi, Kosuge Masami, Sugano Teruyasu, Ebina Toshiaki, Nakayama Naoki, Ishikawa Toshiyuki, Umemura Satoshi

Circulation journal : official journal of the Japanese Circulation Society 72 684 - 685 2008.3

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Assessment of transmural strain profile using tissue strain imaging is an useful method to evaluate the time course of myocardial stunning in patients with reperfused ST elevation acute coronary syndrome

Noriaki Iwahashi, Kazuo Kimura, Jun Okuda, Kengo Tsukahara, Yoshio Tahara, Kiyoshi Hibi, Masami Kosuge, Toshialki Ebina, Shinichi Sumita, Toshiyuki Ishikawa, Kazuaki Uchmo, Satoshi Umemura

JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY 51 ( 10 ) A253 - A253 2008.3

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Noninvasive estimation of left ventricular filling pressure by E/e is a powerful predictor of major adverse cardiac and cerebrovascular events in patients with a first ST elevation acute myocardial infarction

Noriaki Iwahashi, Kazuo Kimura, Jun Okuda, Kengo Tsukahara, Yoshio Tahara, Kiyoshi Hibi, Masami Kosuge, Toshiaki Ebina, Shinnichi Sumita, Toshiyuki Ishikawa, Kazuaki Uchino, Satoshi Umemura

JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY 51 ( 10 ) A295 - A295 2008.3

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Clinical implications of serial changes in ST-segment elevation after reperfusion in patients with anterior acute myocardial infarction.

Jun Okuda, Masami Kosuge, Toshiaki Ebina, Kiyoshi Hibi, Kengo Tsukahara, Noriaki Iwahashi, Mitsuaki Endo, Tatsuya Nakachi, Takayuki Mitsuhashi, Fumiyuki Otsuka, Ikuyoshi Kusama, Katsutaka Hashiba, Naohiro Komura, Satoshi Umemura, Kazuo Kimura

Circulation journal : official journal of the Japanese Circulation Society 72 ( 3 ) 409 - 14 2008.3

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DOI： 10.1253/circj.72.409

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Impact of hyperinsulinemia on tissue characteristics of non-culprit plaque in non-diabetic patients with acute coronary syndrome

Takayuki Mitsuhashi, Kiyoshi Hibi, Masami Kosuge, Toshialki Ebina, Shingo Tsukahara, Jun Okuda, Noriaki Iwahashi, Mitsuaki Endo, Fumiyuki Otsuka, Lkuyoshi Kusama, Naohiro Komura, Satoshi Umemura, Kazuo Kimura

JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY 51 ( 10 ) A332 - A332 2008.3

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Real time/live three-dimensional transthoracic echocardiography is a clinically useful diagnostic tool for acute aortic dissection

Noriaki Iwahashi, Kazuo Kimura, Jun Okuda, Kengo Tsukahara, Yoshio Tahara, Kiyoshi Hibi, Masami Kosuge, Toshiaki Ebina, Shinichi Sumita, Toshiyuki Ishikawa, Kazuaki Uchino, Satoshi Umemura

JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY 51 ( 10 ) A313 - A313 2008.3

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Impact of chronic statin treatment before the onset of ST-elevation acute myocardial infarction on the incidence of plaque rupture detected by intravascular ultrasound

Fumiyuki Otsuka, Kiyoshi Hibi, Ikuyoshi Kusama, Mitsuaki Endou, Takayuki Mitsuhashi, Naohiro Komura, Masami Kosuge, Noriaki Iwahashi, Jyun Okuda, Kengo Tsukahara, Yoshio Tahara, Toshiaki Ebina, Kazuo Kimura, Satoshi Umemura

JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY 51 ( 10 ) A351 - A351 2008.3

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Relation of high-density lipoprotein cholesterol and cigarette smoking to the incidence of plaque rupture detected by intravascular ultrasound in ST-elevation acute myocardial infarction

Fumiyuki Otsuka, Kiyoshi Hibi, Ikuyoshi Kusama, Mitsuaki Endou, Takayuki Mitsuhashi, Naohiro Komura, Masami Kosuge, Noriaki Iwahashi, Jyun Okuda, Kengo Tsukahara, Yoshio Tahara, Toshiaki Ebina, Kazuo Kimura, Satoshi Umemura

JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY 51 ( 10 ) A366 - A366 2008.3

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Noninvasive estimation of left ventricular filling pressure by E/e' is a powerful predictor of major adverse cardiac and cerebrovascular events in patients with a first ST elevation acute myocardial infarction

Noriaki Iwahashi, Kazuo Kimura, Jun Okuda, Kengo Tsukahara, Kiyoshi Hibi, Masami Kosuge, Toshiaki Ebina, Yoshio Tahara

CIRCULATION 116 ( 16 ) 598 - 598 2007.10

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Inducing hypothermia after experimental cardiac arrest with intranasal cooling alone or in combination with cold saline infusion is efficient

Katsutaka Hashiba, Kazuo Kimura, Nakayama Naoki, Yoshio Taara, Noriaki Iwahashi, Jun Okuda, Kengo Tsukahara, Kiyoshi Hibi, Masami Kosuge, Toshiaki Ebina, Satoshi Umemura

CIRCULATION 116 ( 16 ) 581 - 581 2007.10

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ST-Segment elevation resolution in lead aVR: A strong predictor of adverse outcomes in patients with Non-ST-segment elevation acute coronary syndrome

Masami Kosuge, Kazuo Kimura, Toshiaki Ebina, Kiyoshi Hibi, Toshiyuki Ishikawa, Noriaki Iwahashi, Jyun Okuda, Kengo Tsukahara, Kazuaki Uchino, Satoshi Umemura

CIRCULATION 116 ( 16 ) 723 - 723 2007.10

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Impact of insulin resistance on tissue characteristics of non-culprit plaque in non-diabetic patients with acute coronary syndrome

Takayuki Mitsuhashi, KJiyoshi Hibi, Naohiro Komura, Ikuyoshi Kusama, Fumiyuki Otsuka, Mitsuaki Endou, Noriaki Iwahashi, Jun Okuda, Kengo Tsukahara, Masami Kosuge, Toshiaki Ebina, Satoshi Umemura, Kazuo Kimura

CIRCULATION 116 ( 16 ) 796 - 796 2007.10

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Impact of plaque rupture on infarct size in ST-segment elevation anterior acute myocardial infarction

Ikuyoshi Kusama, Kiyoshi Hibi, Masami Kosuge, Naoki Nozawa, Hiroyuki Ozaki, Hideto Yano, Shinnichi Sumita, Kengo Tsukahara, Jun Okuda, Toshiaki Ebina, Satoshi Umemura, Kazuo Kimura

JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY 50 ( 13 ) 1230 - 1237 2007.9

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OJ-004 Nausea and Vomiting as a Predictor of Adverse In-hospital Outcome in Anterior Wall Acute Myocardial Infarction(Acute myocardial infarction, clinical (pathophysiology)-2, The 71st Annual Scientific Meeting of the Japanese Circulation Society)

Kosuge Masami, Kimura Kazuo, Ebina Toshiaki, Hibi Kiyoshi, Tukahara Kengo, Okuda Jun, Iwahashi Noriaki, Endoh Mitsuaki, Tahara Yoshio, Mituhashi Takayuki, Ozaki Hiroyuki, Yano Hideto, Nakati Tatuya, Hashiba Katsutaka, Ohtsuka Fumiyuki, Kusama Ikuyoshi, Komura Naohiro, Umemura Satoshi

Circulation journal : official journal of the Japanese Circulation Society 71 254 - 254 2007.3

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PJ-009 Clinical Implications of Serial Changes in ST Segment Elevation after Reperfusion in Patients with Anterior Acute Myocardial Infarction(Acute myocardial infarction, clinical (diagnosis/treatment)-5, The 71st Annual Scientific Meeting of the Japanese Circulation Society)

Okuda Jun, Kosuge Masami, Ebina Toshiaki, Hibi Kiyoshi, Tukahara Kengo, Tahara Yoshio, Ozaki Hiroyuki, Yano Hideto, Iwahashi Noriaki, Endoh Mitsuaki, Mituhashi Takayuki, Nakachi Tatuya, Hashiba Katsutaka, Kusama Ikuyoshi, Komura Naohiro, Ohtsuka Fumiyuki, Kimura Kazuo, Umemura Satoshi

Circulation journal : official journal of the Japanese Circulation Society 71 472 - 472 2007.3

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PE-086 Elevated C-Reactive Protein Levels are Associated with Rapid Progression of Non-culprit Complex Lesion in Non-ST-segment Elevation Acute Coronary Syndromes(Acute coronary syndrome, basic/clinical-3, The 71st Annual Scientific Meeting of the Japanese Circulation Society)

Nakachi Tatsuya, Kosuge Masami, Ebina Toshiaki, Hibi Kiyoshi, Tukahara Kengo, Okuda Jun, Tahara Yoshio, Iwahashi Noriaki, Ozaki Hiroyuki, Yano Hideto, Endoh Mitsuaki, Mitsuhashi Takayuki, Ohtsuka Fumiyuki, Kusama Ikuyoshi, Komura Naohiro, Hashiba Katsutaka, Kimura Kazuo, Umemura Satoshi

Circulation journal : official journal of the Japanese Circulation Society 71 346 - 346 2007.3

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PE-297 Effects of Angiotensin-II Receptor Blockers on Coronary Atherosclerosis in Patients with Acute Myocardial Infarction Taking Angiotensin-Converting-Enzyme Inhibitors(Atherosclerosis, clinical-07, The 71st Annual Scientific Meeting of the Japanese Circulation Society)

Yano Hideto, Hibi Kiyoshi, Ozaki Hiroyuki, Kusama Ikuyoshi, Endoh Mitsuaki, Mitsuhashi Takayuki, Komura Naohiro, Ebina Toshiaki, Kosuge Masami, Tukahara Kengo, Okuda Jun, Iwahashi Noriaki, Nakachi Tatsuya, Ohtsuka Fumiyuki, Sumita Shinichi, Tahara Yoshio, Sugano Teruyasu, Umemura Satoshi, Kimura Kazuo

Circulation journal : official journal of the Japanese Circulation Society 71 399 - 399 2007.3

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PJ-477 Transmural Myocardial Strain Imaging is a Powerful Tool for Evaluating the Myocardial Stunning in Reperfused ST Elevation Acute Coronary Syndrome(Echo/Doppler-19, The 71st Annual Scientific Meeting of the Japanese Circulation Society)

Iwahashi Noriaki, Kimura Kazuo, Komura Naohiro, Kusama Ikuyoshi, Ohtsuka Fumiyuki, Mitsuhashi Takayuki, Nakachi Tatsuya, Yano Hideto, Ozaki Hiroyuki, Endoh Mitsuaki, Okuda Jun, Tukahara Kengo, Hibi Kiyoshi, Tahara Yoshio, Kosuge Masami, Sumita Shinichi, Ebina Toshiaki, Umemura Satoshi

Circulation journal : official journal of the Japanese Circulation Society 71 591 - 591 2007.3

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Effects of Angiotensin-II receptor blockers on coronary atherosclerosis in patients with acute myocardial infarction taking angiotensin-converting-enzyme inhibitors: Final results of captopril combined with valsartan in acute myocardial infarction study (CVAS)

Hideto Yano, Kiyoshi Hibi, Hiroyuki Ozaki, Ikuyoshi Kusama, Mitsuaki Endou, Takayuki Mitsuhashi, Naohiro Komura, Toshiaki Ebina, Masami Kosuge, Kengo Tsukahara, Jun Okuda, Noriaki Iwahashi, Tatsuya Nakachi, Fumiyuki Otsuka, Satoshi Umemura, Kazuo Kimura

JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY 49 ( 9 ) 316A - 316A 2007.3

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Serum amyloid A is a better predictor of clinical outcomes than C-reactive protein in non-ST-segment elevation acute coronary syndromes

Masami Kosuge, Toshiaki Ebina, Toshiyuki Ishikawa, Kiyoshi Hibi, Kengo Tsukahara, Jyun Okuda, Noriaki Iwahashi, Hiroyuki Ozaki, Hideto Yano, Kuyoshi Kusama, Tastuya Nakati, Satoshi Umemura, Kazuo Kimura

CIRCULATION JOURNAL 71 ( 2 ) 186 - 190 2007.2

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DOI： 10.1253/circj.71.186

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Acute improvement in myocardial function assessed by myocardial strain and strain rate after aortic valve replacement for aortic stenosis. International journal

Noriaki Iwahashi, Satoshi Nakatani, Hideaki Kanzaki, Takuya Hasegawa, Haruhiko Abe, Masafumi Kitakaze

Journal of the American Society of Echocardiography : official publication of the American Society of Echocardiography 19 ( 10 ) 1238 - 44 2006.10

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DOI： 10.1016/j.echo.2006.04.041

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Prognostic significance of inverted T waves in patients with acute pulmonary embolism

M Kosuge, K Kimura, T Ishikawa, T Ebina, K Hibi, K Tsukahara, M Kanna, N Iwahashi, J Okuda, N Nozawa, H Ozaki, H Yano, T Nakati, Kusama, I, S Umemura

CIRCULATION JOURNAL 70 ( 6 ) 750 - 755 2006.6

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DOI： 10.1253/circj.70.750

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OJ-258 Impact of Plaque Rupture on Myocardial Infarct Size in ST-Elevation Anterior Acute Myocardial Infarction(Acute myocardial infarction, clinical (pathophysiology)-2 (IHD) OJ43,Oral Presentation (Japanese),The 70th Anniversary Annual Scientific Meeting of the Japanese Circulation Society)

Kusama Ikuyoshi, Hibi Kiyoshi, Kosuge Masami, Nozawa Naoki, Ozaki Hiroyuki, Yano Hideto, Ebina Toshiaki, Sumita Shinichi, Kanna Masahiko, Tukahara Kengo, Okuda Jun, Iwahashi Noriaki, Nakachi Tatsuya, Tahara Yoshio, Hashiba Katsutaka, Kimura Kazuo, Sugano Teruyasu, Umemura Satoshi

Circulation journal : official journal of the Japanese Circulation Society 70 298 - 298 2006.3

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OJ-134 Elevated C-Reactive Protein on Admission is Associated with Rapid Progression of Atherosclerosis after Coronary Stenting in Unstable Angina(Atherosclerosis, clinical-4 (H) OJ23,Oral Presentation (Japanese),The 70th Anniversary Annual Scientific Meeting of the Japanese Circulation Society)

Nakachi Tatsuya, Kimura Kazuo, Kosuge Masami, Ebina Toshiaki, Sumita Shinnichi, Ebina Toshiaki, Hibi Kiyoshi, Kanna Masahiko, Tukahara Kengo, Okuda Jun, Nozawa Naoki, Iwahashi Noriaki, Ozaki Hiroyuki, Yano Hideto, Kusama Ikuyoshi, Tahara Yoshio, Hashiba Katsutaka, Sugano Teruyasu, Umemura Satoshi

Circulation journal : official journal of the Japanese Circulation Society 70 268 - 268 2006.3

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OJ-092 Mean Platelet Volume on Admission Predicts Microvascular Perfusion and Clinical Outcomes in Patients with Acute Myocardial Infarction(Acute myocardial infarction, clinical (diagnosis/treatment)-3 (IHD) OJ16,Oral Presentation (Japanese),The 70th Anniversary Annual Scientific Meeting of the Japanese Circulation Society)

Kanna Masahiko, Kimura Kazuo, Ebina Toshiaki, Kosuge Masami, Hibi Kiyoshi, Tukahara Kengo, Okuda Jun, Nozawa Naoki, Iwahashi Noriaki, Yano Hideto, Ozaki Hiroyuki, Nakaji Tatsuya, Kusama Ikuyoshi, Umemura Satoshi

Circulation journal : official journal of the Japanese Circulation Society 70 256 - 257 2006.3

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PJ-724 Impact of Elevated Troponin T at Admission on the Non-culprit Plaque Progression in Clinical Unstable Angina Pectoris : an Intravascular Ultrasound Analysis(Atherosclerosis, clinical-14 (H) PJ122,Poster Session (Japanese),The 70th Anniversary Annual Scientific Meeting of the Japanese Circulation Society)

Yano Hideto, Hibi Kiyoshi, Nozawa Naoki, Ozaki Hiroyuki, Kusama Ikuyoshi, Nakachi tatsuya, Iwahashi Noriaki, Okuda Jun, Tukahara Kengo, Kanna Masahiko, Ebina Toshiaki, sumita shinichi, Kosuge Masami, Kimura Kazuo, Tahara Yoshio, Sugano Teruyasu, Umemura Satoshi

Circulation journal : official journal of the Japanese Circulation Society 70 668 - 668 2006.3

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PJ-722 The Non-culprit Complex Plaque of the Patients with Multiple Complex Coronary Plaques(Atherosclerosis, clinical-14 (H) PJ122,Poster Session (Japanese),The 70th Anniversary Annual Scientific Meeting of the Japanese Circulation Society)

Iwahashi Noriaki, Kimura Kazuo, Kusama Ikuyoshi, Nakachi Tatsuya, Ozaki Hiroyuki, Yano Hideto, Nozawa Naoki, Tukahara Kengo, Kanna Masahiko, Tahara Yoshio, Hibi Kiyoshi, Kosuge Masami, Umemura Satoshi

Circulation journal : official journal of the Japanese Circulation Society 70 667 - 667 2006.3

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OE-260 Effects of Angiotensin-II Receptor Blockers on Coronary Atherosclerosis in Patients with Acute Myocardial Infarction Taking Angiotensin-Coverting-Enzyme Inhibitors : Intravascular Ultrasound (IVUS) Analysis(Atherosclerosis, clinical-2 (H) OE44,Oral Presentation (English),The 70th Anniversary Annual Scientific Meeting of the Japanese Circulation Society)

Yano Hideto, Hibi Kiyoshi, Nozawa Naoki, Ozaki Hiroyuki, Kusama Ikuyoshi, Nakachi Tatsuya, Iwahashi Noriaki, Okuda Jun, Tukahara Kengo, Kanna Masahiko, Ebina Toshiaki, sumita sinichi, Kosuge Masami, Kimura Kazuo, Tahara Yoshio, sugano teruyasu, Umemura Satoshi

Circulation journal : official journal of the Japanese Circulation Society 70 213 - 213 2006.3

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OJ-294 Elevated Inflammatory Activity is Associated with Rapid Progression of Complex Coronary Lesion in Patients with Unstable Angina(Acute coronary syndrome, basic/clinical-3 (IHD) OJ49,Oral Presentation (Japanese),The 70th Anniversary Annual Scientific Meeting of the Japanese Circulation Society)

Nakachi Tatsuya, Kimura Kazuo, Kosuge Masami, Ebina Toshiaki, Sumita Shinnichi, Hibi Kiyoshi, Tukahara Kengo, Kanna Masahiko, Kanna Masahiko, Okuda Jun, Nozawa Naoki, Iwahashi Noriaki, Ozaki Hiroyuki, Yano Hideto, Kusama Ikuyoshi, Tahara Yoshio, Hashiba Katsutaka, Sugano Teruyasu, Umemura Satoshi

Circulation journal : official journal of the Japanese Circulation Society 70 307 - 308 2006.3

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Differences between men and women in terms of clinical features of ST-segment elevation acute myocardial infarction

M Kosuge, K Kimura, T Ishikawa, T Ebina, K Hibi, K Tsukahara, M Kanna, N Iwahashi, J Okuda, N Nozawa, H Ozaki, H Yano, T Nakati, Kusama, I, S Umemura

CIRCULATION JOURNAL 70 ( 3 ) 222 - 226 2006.3

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DOI： 10.1253/circj.70.222

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Combined prognostic utility of ST segment in lead aVR and troponin T on admission in non-ST-segment elevation acute coronary syndromes

M Kosuge, K Kimura, T Ishikawa, T Ebina, K Hibi, K Tsukahara, M Kanna, N Iwahashi, J Okuda, N Nozawa, H Ozaki, H Yano, Kusama, I, S Umemura

AMERICAN JOURNAL OF CARDIOLOGY 97 ( 3 ) 334 - 339 2006.2

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DOI： 10.1016/j.amjcard.2005.08.049

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Effects of angiotensin-II receptor blockers on coronary atherosclerosis in patients with acute myocardial infarction taking angiotensin-coverting-enzyme inhibitors: An intravascular ultrasound (IVUS) study

H Yano, K Hibi, K Kimura, N Nozawa, H Ozaki, Kusama, I, M Kosuge, T Ebina, T Nakachi, N Iwahashi, J Okuda, K Tsukahara, M Kanna, S Umemura

JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY 47 ( 4 ) 215A - 215A 2006.2

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Serum amyloid a is a better predictor of clinical outcome than C-reactive protein in non-ST-segment elevation acute coronary syndrome

M Kosuge, K Kimura, T Ebina, K Hibi, N Nozawa, Kusama, I, H Yano, J Okuda, N Iwahashi, T Nakaji, H Ozaki, M Kanna, T Ishikawa, K Tsukahara, S Umemura

JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY 47 ( 4 ) 225A - 225A 2006.2

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Complex plaques and coronary plaque progression in patients with acute myocardial infarction

H Ozaki, K Hibi, H Yano, T Elbina, S Sumita, M Kosuge, M Kanna, K Tsukahara, J Okuda, N Nozawa, N Iwahashi, T Nakachi, L Kusama, Y Tahara, S Umemura, K Kimura

JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY 47 ( 4 ) 329A - 329A 2006.2

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Impact of elevated troponin T level at admission on the non-culprit plaque progression in clinical unstable angina pectoris: A volumetric, intravascular ultrasound analysis

H Yano, K Hibi, K Kimura, N Nozawa, H Ozaki, Kusama, I, M Kosuge, T Ebina, T Nakachi, N Iwahashi, J Okuda, K Tsukahara, M Kanna, S Umemura

JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY 47 ( 4 ) 183A - 183A 2006.2

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Myocardial Diastolic Dysfunction in Aortic Stenosis Assessed by a New Method Using Transmural Myocardial Strain Profile(Echo/Doppler 5 (I), The 69th Annual Scientific Meeting of the Japanese Circulation Society)

Wakami Kazuaki, Nakatani Satoshi, Gotoh Takatoshi, Iwahashi Noriaki, Maruo Takeshi, Hasegawa Takuya, Kanzaki Hideaki, Kitakaze Masafumi, Miyatake Kunio

Circulation journal : official journal of the Japanese Circulation Society 69 283 - 283 2005.3

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Clinical Significance of Plasma Brain Natriuretic Peptide as a Noninvasive Marker of Disease Severity in Aortic Regurgitation(Valvular Heart Disease/Pericarditis/Cardiac Tumor 1 (M), The 69th Annual Scientific Meeting of the Japanese Circulation Society)

Iwahashi Noriaki, Nakatani Satoshi, Kanzaki Hideaki, Kimu Chiyun, Hanatani Akihisa, Hashimura Kazuhiko, Yamagishi Masakazu, Kitakaze Masafumi

Circulation journal : official journal of the Japanese Circulation Society 69 170 - 170 2005.3

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Acute Improvement in Myocardial Function Assessed by Strain and Strain Rate Echocardiography After Aortic Valve Replacement for Aortic Stenosis(Echo/Doppler 6 (I), The 69th Annual Scientific Meeting of the Japanese Circulation Society)

Iwahashi Noriaki, Nakatani Satoshi, Wakami Kazuaki, Hasegawa Takuya, Abe Haruhiko, Katoh Mahoto, Tanaka Jun, Kanzaki Hideaki, Kitakaze Masafumi, Miyatake Kunio

Circulation journal : official journal of the Japanese Circulation Society 69 396 - 396 2005.3

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Cardiac tumor as an initial manifestation of acquired immunodeficiency syndrome

N Iwahashi, S Nakatani, H Kakuchi, M Yamagishi, K Fukuchi, Y Ishida, K Hirooka, Y Koretsune, C Ueta, T Shirasaka, M Kitakaze

CIRCULATION JOURNAL 69 ( 2 ) 243 - 245 2005.2

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DOI： 10.1253/circj.69.243

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脊髄虚血を合併した急性大動脈解離の1例

IWAHASHI NORIAKI, NISHIGAMI KAZUHIRO, NAGAYA NORITOSHI, HAYASHI TOKIO, NAKANISHI NORIFUMI, NONOGI HIROSHI, OE HIROSHI, HIGASHI MASAHIRO, TANAKA RYOICHI

心臓 36 ( 10 ) 693 - 698 2004.10

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DOI： 10.11281/shinzo1969.36.10_693

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Presentations

急性心筋梗塞における心臓超音波検査 International conference

岩橋徳明

日本心エコー図学会 2016.4

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低心機能急性心不全症例における頻脈性心房性不整脈のオノアクトを用いた心拍コントロール

岩橋徳明, 海老名俊明, 梅村敏, 木村一雄

第19回日本心不全学会学術集会、大阪 2015.10

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早期再灌流療法後にHFpEFに進展するSTEMI症例の特徴: 経口利尿剤のメリットと危険性

岩橋徳明, 海老名俊明, 梅村敏, 木村一雄

第19回日本心不全学会学術集会、大阪 2015.10

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虚血性心不全：虚血性心不全症例における各種モダリティーを用いた形態および血行動態評価の重要性

岩橋徳明

第18回日本心不全学会学術集会；大阪 2014.10

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岩橋徳明（教育公演）急性心筋梗塞の予後予測におけるベッドサイド心筋ストレイン法の役割

岩橋徳明

第35回日本冠疾患学会学術集会教育講演 2021.12

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岩橋徳明（教育公演）急性冠動脈症候群の合併症、総論第32回日本心エコー図学会学術集会、教育セッション：急性冠症候群の合併症.

岩橋徳明

2021.4

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シンポジウム・会長特別講演岩橋徳明、桐ヶ谷仁、南本祐吾、花島陽平、秋山英一、岡田興造、松澤泰志、前島信彦、日比潔、小菅雅美、海老名俊明、田村功一、木村一雄.急性冠症候群における血糖変動は重要な予後予測因子である。循環器医が考える糖尿病管理. 第63回日本心臓病学会学術集会.2019年9月13日.名古屋.

岩橋徳明

2019.9

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特別講演シンポジウム、心不全に活かす岩橋徳明、海老名俊明、木村一雄。心房細動合併急性心不全における心拍コントロールにおける超音波検査の意義、ランジオロールの治療における検討。日本超音波医学会学術集会総会。神戸。2018年6月。

岩橋徳明

2017

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新技術を臨床に生かす

岩橋徳明

日本超音波医学会総会；大阪 2013.5

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教育講演心エコーを始めるにあたって. 第259回日本循環器学会関東甲信越地方会教育

岩橋徳明

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Echocardiography for ACS International conference

IWAHASHI Noriaki

2016.5

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Language：English

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Research Projects

岩橋徳明 2021年新規心不全薬における心臓超音波検査の意義日本ベーリンガーインゲルハイム株式会社ライフサイエンス・リサーチサポート

2021.4

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2020年急性心筋梗塞における睡眠障害の血管や心機能に及ぼす影響に関する研究日本ベーリンガーインゲルハイム株式会社ライフサイエンス・リサーチサポート

2020年急性心筋梗塞における睡眠障害の血管や心機能に及ぼす影響に関する研究日本ベーリンガーインゲルハイム株式会社ライフサイエンス・リサーチサポート

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Teaching Experience

Ischemic heart disease

2023.11

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Cardiac catheterization

2023.4

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Myocardial infarction

2023.4

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Pulmonary hypertension

2023.4

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Coronary intervention

2023.4

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急性心不全

2012.4

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慢性心不全

2007.4

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Emergency medicine

2005.5

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診療録の記載、目的、方法、意義、考えから

2005 Institution：横浜市立大学

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心臓超音波

2005

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感染性心内膜炎

2005

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救命救急師養成

2005 - 2008

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Social Activities

岩橋徳明. 特発性拡張型・肥大型・拘束型心筋症, 心不全全般の管理横浜市難病講演会

Role(s)： Appearance,　Lecturer,　Advisor

2015

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Type：Lecture

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